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SNRPA small nuclear ribonucleoprotein polypeptide A [Homo sapiens (human)]

Gene Symbol SNRPA
Entrez Gene ID 6626
Full Name small nuclear ribonucleoprotein polypeptide A
Synonyms Mud1, U1-A, U1A
General protein information
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

19

19q13.1

Summary The protein encoded by this gene associates with stem loop II of the U1 small nuclear ribonucleoprotein, which binds the 5' splice site of precursor mRNAs and is required for splicing. The encoded protein autoregulates itself by polyadenylation inhibition of its own pre-mRNA via dimerization and has been implicated in the coupling of splicing and polyadenylation. [provided by RefSeq, Oct 2010]. lac of sum
Disorder MIM:

182285

Disorder Html:





The following SNRPA gene sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SNRPA gene which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu15951 NM_004596 Homo sapiens small nuclear ribonucleoprotein polypeptide A (SNRPA), mRNA. pcDNA3.1+/C-(K)DYK or customized vector 5-7 $199

*Business Day
**You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.


CloneID OHu15951
Accession Version NM_004596.4 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 849bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector Document: User manual_GenEZ ORF Clone Products.pdf (pdf)
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags Document: MSDS_GenEZ ORF Clone Products.pdf (pdf)
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product U1 small nuclear ribonucleoprotein A
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from CN286572.1, BC000405.2, AC020945.6 and BQ002918.1. On Apr 28, 2010 this sequence version replaced gi:39725715. Summary: The protein encoded by this gene associates with stem loop II of the U1 small nuclear ribonucleoprotein, which binds the 5' splice site of precursor mRNAs and is required for splicing. The encoded protein autoregulates itself by polyadenylation inhibition of its own pre-mRNA via dimerization and has been implicated in the coupling of splicing and polyadenylation. [provided by RefSeq, Oct 2010]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC000405.2, X06347.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
ATGGCAGTTC CCGAGACCCG CCCTAACCAC ACTATTTATA TCAACAACCT CAATGAGAAG 
ATCAAGAAGG ATGAGCTAAA AAAGTCCCTG TACGCCATCT TCTCCCAGTT TGGCCAGATC
CTGGATATCC TGGTATCACG GAGCCTGAAG ATGAGGGGCC AGGCCTTTGT CATCTTCAAG
GAGGTCAGCA GCGCCACCAA CGCCCTGCGC TCCATGCAGG GTTTCCCTTT CTATGACAAA
CCTATGCGTA TCCAGTATGC CAAGACCGAC TCAGATATCA TTGCCAAGAT GAAAGGCACC
TTCGTGGAGC GGGACCGCAA GCGGGAGAAG AGGAAGCCCA AGAGCCAGGA GACCCCGGCC
ACCAAGAAGG CTGTGCAAGG CGGGGGAGCC ACCCCCGTGG TGGGGGCTGT CCAGGGGCCT
GTCCCGGGCA TGCCGCCGAT GACTCAGGCG CCCCGCATTA TGCACCACAT GCCGGGCCAG
CCGCCCTACA TGCCGCCCCC TGGTATGATC CCCCCGCCAG GCCTTGCACC TGGCCAGATC
CCACCAGGGG CCATGCCCCC GCAGCAGCTT ATGCCAGGAC AGATGCCCCC TGCCCAGCCT
CTTTCTGAGA ATCCACCGAA TCACATCTTG TTCCTCACCA ACCTGCCAGA GGAGACCAAC
GAGCTCATGC TGTCCATGCT TTTCAATCAG TTCCCTGGCT TCAAGGAGGT CCGTCTGGTA
CCCGGGCGGC ATGACATCGC CTTCGTGGAG TTTGACAATG AGGTACAGGC AGGGGCAGCT
CGCGATGCCC TGCAGGGCTT TAAGATCACG CAGAACAACG CCATGAAGAT CTCCTTTGCC
AAGAAGTAG
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_004587.1
CDS556..1404
Misc Feature(1)508..510(+)
Misc Feature(2)559..561(+)
Misc Feature(3)574..840(+)
Misc Feature(4)586..807(+)
Misc Feature(5)592..831(+)
Misc Feature(6)733..735(+)
Misc Feature(7)946..948(+)
Misc Feature(8)1162..1401(+)
Misc Feature(9)1183..1362(+)
Exon (1)1..628
Gene:SNRPA
Gene Synonym:
Exon (2)629..801
Gene:SNRPA
Gene Synonym:
Exon (3)802..981
Gene:SNRPA
Gene Synonym:
Exon (4)982..1155
Gene:SNRPA
Gene Synonym:
Exon (5)1156..1244
Gene:SNRPA
Gene Synonym:
Exon (6)1245..1629
Gene:SNRPA
Gene Synonym:
Translation
Position Chain Variation Link
12 12 a, g dbSNP:192585880
55 55 c, t dbSNP:185581242
56 56 c, g dbSNP:552770266
72 72 a, g dbSNP:16974492
78 78 c, t dbSNP:376964186
86 86 a, t dbSNP:111978082
88 88 a, g dbSNP:773618582
92 92 c, t dbSNP:761092524
135 135 c, g dbSNP:556509676
156 156 c, g dbSNP:575181971
176 176 c, t dbSNP:545741102
212 212 a, c dbSNP:766722242
281 281 c, t dbSNP:557973182
288 288 g, t dbSNP:1455434
315 315 a, g dbSNP:377665450
340 340 c, g dbSNP:370874353
350 350 c, t dbSNP:759905151
354 354 c, g dbSNP:182084754
368 368 c, g dbSNP:754376590
375 375 g, t dbSNP:765783027
377 377 c, g dbSNP:530185039
380 380 a, c dbSNP:570655182
418 418 c, g dbSNP:1457141
427 427 c, t dbSNP:75531803
450 450 c, t dbSNP:531273022
457 457 a, g dbSNP:536919973
477 477 c, t dbSNP:368523279
508 508 c, t dbSNP:771278280
516 516 a, c dbSNP:140145098
518 518 c, t dbSNP:11558816
524 524 c, t dbSNP:201840992
525 525 c, t dbSNP:768109901
526 526 a, c dbSNP:370795053
528 528 g, t dbSNP:761493788
529 529 c, t dbSNP:764901735
545 545 c, t dbSNP:750032542
549 549 a, t dbSNP:762754472
550 550 a, c dbSNP:766133681
552 552 c, g dbSNP:751521543
555 555 c, t dbSNP:754926843
566 566 c, t dbSNP:781175552
569 569 a, g dbSNP:528661832
573 573 c, t dbSNP:752218725
576 576 c, t dbSNP:375774122
577 577 c, g dbSNP:546755498
587 587 c, g dbSNP:771202299
588 588 g, t dbSNP:779329468
593 593 a, g dbSNP:779361733
594 594 c, t dbSNP:377659020
595 595 a, g dbSNP:772602431
600 600 c, t dbSNP:775935843
602 602 a, c, g dbSNP:761336247
603 603 c, t dbSNP:138619399
606 606 c, t dbSNP:762665160
627 627 c, t dbSNP:766141575
631 631 c, t dbSNP:765518957
632 632 -, a dbSNP:773649543
641 641 a, c dbSNP:11558817
645 645 a, c, g dbSNP:752716847
648 648 c, t dbSNP:149329472
654 654 a, c dbSNP:758798735
657 657 c, t dbSNP:375457307
663 663 a, g dbSNP:747575670
667 667 g, t dbSNP:144586987
672 672 c, g dbSNP:755452689
678 678 a, g dbSNP:777302944
685 685 c, t dbSNP:560074271
687 687 a, c, g dbSNP:748856827
691 691 a, t dbSNP:774066197
694 694 c, t dbSNP:368973112
695 695 a, g dbSNP:373207469
696 696 a, g dbSNP:775410017
699 699 c, t dbSNP:760736400
700 700 c, t dbSNP:764160217
707 707 c, t dbSNP:143591779
708 708 -, ga dbSNP:760966739
712 712 g, t dbSNP:776383821
713 713 -, ata dbSNP:769447827
729 729 c, t dbSNP:202225969
734 734 -, a dbSNP:35864792
747 747 c, t dbSNP:542547484
748 748 a, g dbSNP:750727750
756 756 c, t dbSNP:758607872
759 759 c, t dbSNP:766781321
765 765 c, t dbSNP:751887059
768 768 c, t dbSNP:376435515
771 771 c, g dbSNP:755293335
772 772 c, t dbSNP:781731783
794 794 a, g dbSNP:753084366
795 795 a, c, g, t dbSNP:2230694
800 800 c, t dbSNP:778280948
803 803 a, g dbSNP:773157493
808 808 c, t dbSNP:763038967
819 819 g, t dbSNP:770937932
822 822 c, t dbSNP:138646758
830 830 a, g dbSNP:374456745
835 835 a, g dbSNP:767980536
836 836 c, t dbSNP:752981928
840 840 c, t dbSNP:557608943
853 853 a, t dbSNP:138535346
855 855 c, t dbSNP:764531350
858 858 c, t dbSNP:201788574
861 861 a, g dbSNP:561750476
871 871 c, t dbSNP:757989135
872 872 a, c, g dbSNP:765984414
877 877 c, t dbSNP:754567162
878 878 a, g dbSNP:540507848
878 878 -, g dbSNP:763662325
879 879 a, g dbSNP:747928966
885 885 a, g dbSNP:755885235
891 891 a, g dbSNP:367777373
893 893 c, t dbSNP:777699006
894 894 c, t dbSNP:749154496
898 898 a, g dbSNP:771064652
908 908 a, c dbSNP:555710684
910 910 c, g dbSNP:746136877
911 911 c, t dbSNP:557419180
912 912 a, g, t dbSNP:775733682
926 926 c, t dbSNP:764454884
928 928 a, g dbSNP:146345577
936 936 c, t dbSNP:374319458
937 937 a, c, g dbSNP:762398926
942 942 a, c dbSNP:770591655
945 945 c, t dbSNP:751086817
947 947 a, c, t dbSNP:754474688
948 948 c, t dbSNP:752332476
951 951 c, t dbSNP:77290177
952 952 a, g dbSNP:368200642
954 954 g, t dbSNP:749279557
960 960 a, g dbSNP:757162946
963 963 g, t dbSNP:779004316
965 965 a, t dbSNP:372396909
977 977 g, t dbSNP:772134637
980 980 c, t dbSNP:775580802
981 981 a, g dbSNP:572892523
989 989 c, t dbSNP:780169966
990 990 a, g dbSNP:747247144
992 992 c, t dbSNP:768970890
995 995 c, t dbSNP:781528211
996 996 a, g dbSNP:748549557
1004 1004 c, t dbSNP:770222165
1005 1005 a, g dbSNP:773592729
1008 1008 c, t dbSNP:115500434
1009 1009 c, t dbSNP:771537539
1010 1010 a, g dbSNP:775040575
1012 1012 a, t dbSNP:760283374
1016 1016 c, t dbSNP:763766715
1017 1017 g, t dbSNP:753439418
1018 1018 a, c dbSNP:763024094
1022 1022 a, g dbSNP:761601883
1023 1023 c, t dbSNP:201615676
1029 1029 a, g dbSNP:372273946
1030 1030 a, g dbSNP:758335812
1036 1036 c, t dbSNP:780040463
1037 1037 c, t dbSNP:751695164
1038 1038 a, g dbSNP:374030639
1049 1049 c, t dbSNP:535313716
1050 1050 a, g dbSNP:146065356
1053 1053 a, c dbSNP:770344961
1056 1056 -, t dbSNP:751075123
1057 1057 c, g dbSNP:778183482
1059 1059 c, t dbSNP:749807116
1068 1068 c, t dbSNP:771436011
1070 1070 a, c, t dbSNP:774679356
1071 1071 a, g, t dbSNP:557086367
1076 1076 g, t dbSNP:761443984
1082 1082 c, t dbSNP:764992919
1085 1085 c, g dbSNP:773032435
1089 1089 c, t dbSNP:368227905
1103 1103 a, g dbSNP:766365358
1111 1111 c, t dbSNP:374666711
1116 1116 a, c, g dbSNP:755108553
1120 1120 c, g dbSNP:753022671
1129 1129 c, g dbSNP:756380978
1132 1132 a, g dbSNP:778037728
1137 1137 g, t dbSNP:749693100
1138 1138 a, g dbSNP:757513318
1141 1141 c, g dbSNP:779487577
1149 1149 c, t dbSNP:746369733
1152 1152 c, g dbSNP:768214332
1156 1156 c, t dbSNP:760821013
1159 1159 g, t dbSNP:764013546
1163 1163 a, g dbSNP:754147722
1167 1167 g, t dbSNP:761919904
1172 1172 c, t dbSNP:765631091
1183 1183 c, t dbSNP:750819200
1185 1185 a, g dbSNP:140010893
1188 1188 c, t dbSNP:780556398
1200 1200 a, g dbSNP:752001227
1215 1215 c, t dbSNP:116493527
1216 1216 a, g dbSNP:777130046
1244 1244 a, g dbSNP:749015965
1257 1257 a, c dbSNP:375879544
1266 1266 c, t dbSNP:747007224
1269 1269 g, t dbSNP:367663559
1270 1270 c, t dbSNP:144832566
1278 1278 c, t dbSNP:776580160
1290 1290 c, t dbSNP:748187408
1293 1293 c, t dbSNP:148570725
1294 1294 a, g dbSNP:773487223
1299 1299 c, t dbSNP:540430809
1312 1312 a, g dbSNP:766783077
1315 1315 c, g dbSNP:774552241
1317 1317 a, g dbSNP:561824535
1320 1320 a, g dbSNP:371832037
1328 1328 c, g dbSNP:753191262
1338 1338 a, c dbSNP:756833065
1339 1339 a, g dbSNP:764836571
1364 1364 c, t dbSNP:750149923
1365 1365 a, g dbSNP:142921812
1370 1370 a, g dbSNP:779715184
1374 1374 c, t dbSNP:142041325
1400 1400 a, t dbSNP:754741975
1402 1402 c, t dbSNP:780993076
1405 1405 c, t dbSNP:748108651
1407 1407 c, g dbSNP:562449525
1409 1409 g, t dbSNP:769916012
1418 1418 c, g dbSNP:376777993
1419 1419 a, g dbSNP:779275337
1432 1432 c, t dbSNP:749556625
1436 1436 c, t dbSNP:13108
1437 1437 a, g dbSNP:774586607
1442 1442 a, g dbSNP:200257392
1447 1447 c, t dbSNP:376380531
1452 1452 c, t dbSNP:775928659
1484 1484 a, g dbSNP:370715274
1489 1489 c, t dbSNP:773408683
1503 1503 c, t dbSNP:1058852
1516 1516 -, gtga dbSNP:577261696
1530 1530 a, g dbSNP:560449972
1535 1535 a, g dbSNP:527486727
1536 1536 c, t dbSNP:548879956
1566 1566 a, g dbSNP:575503492
1588 1588 c, t dbSNP:568558206
1626 1626 a, g dbSNP:372105982

Target ORF information:

RefSeq Version NM_004596
Organism Homo sapiens (human)
Definition Homo sapiens small nuclear ribonucleoprotein polypeptide A (SNRPA), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_004596

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
ATGGCAGTTC CCGAGACCCG CCCTAACCAC ACTATTTATA TCAACAACCT CAATGAGAAG 
ATCAAGAAGG ATGAGCTAAA AAAGTCCCTG TACGCCATCT TCTCCCAGTT TGGCCAGATC
CTGGATATCC TGGTATCACG GAGCCTGAAG ATGAGGGGCC AGGCCTTTGT CATCTTCAAG
GAGGTCAGCA GCGCCACCAA CGCCCTGCGC TCCATGCAGG GTTTCCCTTT CTATGACAAA
CCTATGCGTA TCCAGTATGC CAAGACCGAC TCAGATATCA TTGCCAAGAT GAAAGGCACC
TTCGTGGAGC GGGACCGCAA GCGGGAGAAG AGGAAGCCCA AGAGCCAGGA GACCCCGGCC
ACCAAGAAGG CTGTGCAAGG CGGGGGAGCC ACCCCCGTGG TGGGGGCTGT CCAGGGGCCT
GTCCCGGGCA TGCCGCCGAT GACTCAGGCG CCCCGCATTA TGCACCACAT GCCGGGCCAG
CCGCCCTACA TGCCGCCCCC TGGTATGATC CCCCCGCCAG GCCTTGCACC TGGCCAGATC
CCACCAGGGG CCATGCCCCC GCAGCAGCTT ATGCCAGGAC AGATGCCCCC TGCCCAGCCT
CTTTCTGAGA ATCCACCGAA TCACATCTTG TTCCTCACCA ACCTGCCAGA GGAGACCAAC
GAGCTCATGC TGTCCATGCT TTTCAATCAG TTCCCTGGCT TCAAGGAGGT CCGTCTGGTA
CCCGGGCGGC ATGACATCGC CTTCGTGGAG TTTGACAATG AGGTACAGGC AGGGGCAGCT
CGCGATGCCC TGCAGGGCTT TAAGATCACG CAGAACAACG CCATGAAGAT CTCCTTTGCC
AAGAAGTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.