×

SNRPN cDNA ORF clone, Homo sapiens (human)

Gene Symbol SNRPN
Entrez Gene ID 6638
Full Name small nuclear ribonucleoprotein polypeptide N
Synonyms HCERN3, PWCR, RT-LI, SM-D, SMN, SNRNP-N, SNURF-SNRPN, sm-N
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

15

15q11.2

Summary The protein encoded by this gene is one polypeptide of a small nuclear ribonucleoprotein complex and belongs to the snRNP SMB/SMN family. The protein plays a role in pre-mRNA processing, possibly tissue-specific alternative splicing events. Although individual snRNPs are believed to recognize specific nucleic acid sequences through RNA-RNA base pairing, the specific role of this family member is unknown. The protein arises from a bicistronic transcript that also encodes a protein identified as the SNRPN upstream reading frame (SNURF). Multiple transcription initiation sites have been identified and extensive alternative splicing occurs in the 5' untranslated region. Additional splice variants have been described but sequences for the complete transcripts have not been determined. The 5' UTR of this gene has been identified as an imprinting center. Alternative splicing or deletion caused by a translocation event in this paternally-expressed region is responsible for Angelman syndrome or Prader-Willi syndrome due to parental imprint switch failure. [provided by RefSeq, Jul 2008]. lac of sum
Disorder MIM:

182279

Disorder Html: Prader-Willi syndrome, 176270 (3)

mRNA and Protein(s)

mRNA Protein Name
NM_003097 NP_003088 small nuclear ribonucleoprotein-associated protein N
NM_022805 NP_073716 small nuclear ribonucleoprotein-associated protein N
NM_022806 NP_073717 small nuclear ribonucleoprotein-associated protein N
NM_022807 NP_073718 small nuclear ribonucleoprotein-associated protein N
NM_022808 NP_073719 small nuclear ribonucleoprotein-associated protein N



Homo sapiens (human) SNRPN NP_003088.1
Pan troglodytes (chimpanzee) SNRPN NP_001243726.1
Macaca mulatta (Rhesus monkey) SNRPN XP_001108013.1
Canis lupus familiaris (dog) SNRPN XP_005618293.1
Bos taurus (cattle) SNRPN NP_001073265.1
Mus musculus (house mouse) Snrpn NP_001076430.1
Rattus norvegicus (Norway rat) Snrpn NP_112379.1
Gallus gallus (chicken) SNRPB NP_989930.1
Danio rerio (zebrafish) snrpb NP_991230.1
Drosophila melanogaster (fruit fly) SmB NP_001188780.1
Caenorhabditis elegans snr-2 NP_493348.1
Xenopus (Silurana) tropicalis (western clawed frog) snrpb NP_001001198.1


GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following SNRPN gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SNRPN cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu17081
NM_003097 Homo sapiens small nuclear ribonucleoprotein polypeptide N (SNRPN), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$99.50-$139.30
$199.00
OHu17081
NM_022805 Homo sapiens small nuclear ribonucleoprotein polypeptide N (SNRPN), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$99.50-$139.30
$199.00
OHu17081
NM_022806 Homo sapiens small nuclear ribonucleoprotein polypeptide N (SNRPN), transcript variant 3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$99.50-$139.30
$199.00
OHu17081
NM_022807 Homo sapiens small nuclear ribonucleoprotein polypeptide N (SNRPN), transcript variant 4, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$99.50-$139.30
$199.00
OHu17081
NM_022808 Homo sapiens small nuclear ribonucleoprotein polypeptide N (SNRPN), transcript variant 5, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$99.50-$139.30
$199.00
Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone 30% OFF
2-4 Clone 40% OFF
5 or more Clone 50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu17081
Clone ID Related Accession (Same CDS sequence) NM_003097 , NM_022805 , NM_022806 , NM_022807 , NM_022808
Accession Version NM_003097.3 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 723bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product small nuclear ribonucleoprotein-associated protein N
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from X15892.1 and U41303.1. On or before Aug 31, 2013 this sequence version replaced gi:530405199, gi:169207847, gi:113425512, gi:13027651. Transcript Variant: This variant (1) utilizes alternative exon 1 and represents the predominant variant. Since this variant alone contains exon 1, it is the only one which also contains the complete open reading frame for SNURF. Alternative splicing takes place only in the 5' UTR, resulting in variants that all share exons 2-10, encoding identical proteins. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##RefSeq-Attributes-START## bicistronic transcript :: PMID: 10318933 imprinted gene :: PMID: 7512861 ##RefSeq-Attributes-END## ##Evidence-Data-START## Transcript exon combination :: U41303.1, BC018809.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

1
61
121
181
241
301
361
421
481
541
601
661
721
ATGACTGTTG GCAAGAGTAG CAAGATGCTG CAGCACATTG ACTATAGAAT GAGATGTATC 
CTGCAAGATG GCCGAATCTT CATTGGCACC TTTAAGGCTT TTGACAAGCA TATGAATTTG
ATCCTCTGTG ATTGTGATGA GTTCAGAAAG ATCAAGCCAA AGAATGCGAA GCAACCAGAG
CGTGAAGAAA AGCGGGTTTT GGGTCTGGTG TTGCTGCGTG GGGAGAACTT GGTATCCATG
ACTGTGGAGG GGCCACCCCC CAAAGATACT GGCATTGCTC GGGTACCACT TGCTGGAGCT
GCTGGAGGCC CTGGGGTTGG TAGGGCAGCT GGTAGAGGAG TACCAGCTGG TGTGCCAATT
CCCCAGGCCC CTGCTGGATT GGCAGGCCCT GTCCGAGGAG TTGGGGGACC ATCCCAGCAG
GTAATGACTC CACAGGGAAG AGGCACTGTA GCAGCTGCTG CTGTTGCTGC GACTGCCAGT
ATTGCTGGAG CCCCAACACA GTACCCACCA GGACGGGGCA CTCCGCCCCC ACCCGTCGGC
AGAGCAACCC CACCTCCAGG CATTATGGCT CCTCCACCTG GTATGAGACC ACCCATGGGC
CCACCAATTG GGCTTCCCCC TGCTCGAGGG ACGCCAATAG GCATGCCGCC TCCGGGAATG
AGACCCCCTC CACCAGGCAT TAGAGGTCCA CCTCCCCCAG GAATGCGTCC ACCAAGACCT
TAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_003088.1
CDS466..1188
Misc Feature(1)1..75(+)
Misc Feature(2)62..277(+)
Misc Feature(3)367..369(+)
Misc Feature(4)478..714(+)
Misc Feature(5)487..711(+)
Misc Feature(6)514..594(+)
Misc Feature(7)523..702(+)
Misc Feature(8)571..690(+)
Misc Feature(9)670..705(+)
Misc Feature(10)988..1173(+)
Exon (1)1..75
Gene:SNRPN
Gene Synonym:
Exon (2)76..171
Gene:SNRPN
Gene Synonym:
Exon (3)172..322
Gene:SNRPN
Gene Synonym:
Exon (4)323..468
Gene:SNRPN
Gene Synonym:
Exon (5)469..620
Gene:SNRPN
Gene Synonym:
Exon (6)621..732
Gene:SNRPN
Gene Synonym:
Exon (7)733..885
Gene:SNRPN
Gene Synonym:
Exon (8)886..1024
Gene:SNRPN
Gene Synonym:
Exon (9)1025..1150
Gene:SNRPN
Gene Synonym:
Exon (10)1151..1326
Gene:SNRPN
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_003097
Organism Homo sapiens (human)
Definition Homo sapiens small nuclear ribonucleoprotein polypeptide N (SNRPN), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_003097

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
ATGACTGTTG GCAAGAGTAG CAAGATGCTG CAGCACATTG ACTATAGAAT GAGATGTATC 
CTGCAAGATG GCCGAATCTT CATTGGCACC TTTAAGGCTT TTGACAAGCA TATGAATTTG
ATCCTCTGTG ATTGTGATGA GTTCAGAAAG ATCAAGCCAA AGAATGCGAA GCAACCAGAG
CGTGAAGAAA AGCGGGTTTT GGGTCTGGTG TTGCTGCGTG GGGAGAACTT GGTATCCATG
ACTGTGGAGG GGCCACCCCC CAAAGATACT GGCATTGCTC GGGTACCACT TGCTGGAGCT
GCTGGAGGCC CTGGGGTTGG TAGGGCAGCT GGTAGAGGAG TACCAGCTGG TGTGCCAATT
CCCCAGGCCC CTGCTGGATT GGCAGGCCCT GTCCGAGGAG TTGGGGGACC ATCCCAGCAG
GTAATGACTC CACAGGGAAG AGGCACTGTA GCAGCTGCTG CTGTTGCTGC GACTGCCAGT
ATTGCTGGAG CCCCAACACA GTACCCACCA GGACGGGGCA CTCCGCCCCC ACCCGTCGGC
AGAGCAACCC CACCTCCAGG CATTATGGCT CCTCCACCTG GTATGAGACC ACCCATGGGC
CCACCAATTG GGCTTCCCCC TGCTCGAGGG ACGCCAATAG GCATGCCGCC TCCGGGAATG
AGACCCCCTC CACCAGGCAT TAGAGGTCCA CCTCCCCCAG GAATGCGTCC ACCAAGACCT
TAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu17081
Clone ID Related Accession (Same CDS sequence) NM_003097 , NM_022805 , NM_022806 , NM_022807 , NM_022808
Accession Version NM_022805.2 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 723bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product small nuclear ribonucleoprotein-associated protein N
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from U41303.1 and L80004.1. On Apr 4, 2003 this sequence version replaced gi:13027643. Transcript Variant: This variant (2) lacks exon 1 but utilizes upstream, non-coding exons u1A, u2 and u4. Alternative splicing takes place only in the 5' UTR, resulting in variants that all share exons 2-10, encoding identical proteins. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##RefSeq-Attributes-START## imprinted gene :: PMID: 7512861 ##RefSeq-Attributes-END## ##Evidence-Data-START## Transcript exon combination :: L80004.1, AK222633.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2144335 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

1
61
121
181
241
301
361
421
481
541
601
661
721
ATGACTGTTG GCAAGAGTAG CAAGATGCTG CAGCACATTG ACTATAGAAT GAGATGTATC 
CTGCAAGATG GCCGAATCTT CATTGGCACC TTTAAGGCTT TTGACAAGCA TATGAATTTG
ATCCTCTGTG ATTGTGATGA GTTCAGAAAG ATCAAGCCAA AGAATGCGAA GCAACCAGAG
CGTGAAGAAA AGCGGGTTTT GGGTCTGGTG TTGCTGCGTG GGGAGAACTT GGTATCCATG
ACTGTGGAGG GGCCACCCCC CAAAGATACT GGCATTGCTC GGGTACCACT TGCTGGAGCT
GCTGGAGGCC CTGGGGTTGG TAGGGCAGCT GGTAGAGGAG TACCAGCTGG TGTGCCAATT
CCCCAGGCCC CTGCTGGATT GGCAGGCCCT GTCCGAGGAG TTGGGGGACC ATCCCAGCAG
GTAATGACTC CACAGGGAAG AGGCACTGTA GCAGCTGCTG CTGTTGCTGC GACTGCCAGT
ATTGCTGGAG CCCCAACACA GTACCCACCA GGACGGGGCA CTCCGCCCCC ACCCGTCGGC
AGAGCAACCC CACCTCCAGG CATTATGGCT CCTCCACCTG GTATGAGACC ACCCATGGGC
CCACCAATTG GGCTTCCCCC TGCTCGAGGG ACGCCAATAG GCATGCCGCC TCCGGGAATG
AGACCCCCTC CACCAGGCAT TAGAGGTCCA CCTCCCCCAG GAATGCGTCC ACCAAGACCT
TAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_073716.1
CDS745..1467
Misc Feature(1)1..166(+)
Misc Feature(2)167..240(+)
Misc Feature(3)241..354(+)
Misc Feature(4)646..648(+)
Misc Feature(5)757..993(+)
Misc Feature(6)766..990(+)
Misc Feature(7)793..873(+)
Misc Feature(8)802..981(+)
Misc Feature(9)850..969(+)
Misc Feature(10)949..984(+)
Misc Feature(11)1267..1452(+)
Exon (1)1..166
Gene:SNRPN
Gene Synonym:
Exon (2)167..240
Gene:SNRPN
Gene Synonym:
Exon (3)241..354
Gene:SNRPN
Gene Synonym:
Exon (4)355..450
Gene:SNRPN
Gene Synonym:
Exon (5)451..601
Gene:SNRPN
Gene Synonym:
Exon (6)602..747
Gene:SNRPN
Gene Synonym:
Exon (7)748..899
Gene:SNRPN
Gene Synonym:
Exon (8)900..1011
Gene:SNRPN
Gene Synonym:
Exon (9)1012..1164
Gene:SNRPN
Gene Synonym:
Exon (10)1165..1303
Gene:SNRPN
Gene Synonym:
Exon (11)1304..1429
Gene:SNRPN
Gene Synonym:
Exon (12)1430..1605
Gene:SNRPN
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_022805
Organism Homo sapiens (human)
Definition Homo sapiens small nuclear ribonucleoprotein polypeptide N (SNRPN), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_022805

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
ATGACTGTTG GCAAGAGTAG CAAGATGCTG CAGCACATTG ACTATAGAAT GAGATGTATC 
CTGCAAGATG GCCGAATCTT CATTGGCACC TTTAAGGCTT TTGACAAGCA TATGAATTTG
ATCCTCTGTG ATTGTGATGA GTTCAGAAAG ATCAAGCCAA AGAATGCGAA GCAACCAGAG
CGTGAAGAAA AGCGGGTTTT GGGTCTGGTG TTGCTGCGTG GGGAGAACTT GGTATCCATG
ACTGTGGAGG GGCCACCCCC CAAAGATACT GGCATTGCTC GGGTACCACT TGCTGGAGCT
GCTGGAGGCC CTGGGGTTGG TAGGGCAGCT GGTAGAGGAG TACCAGCTGG TGTGCCAATT
CCCCAGGCCC CTGCTGGATT GGCAGGCCCT GTCCGAGGAG TTGGGGGACC ATCCCAGCAG
GTAATGACTC CACAGGGAAG AGGCACTGTA GCAGCTGCTG CTGTTGCTGC GACTGCCAGT
ATTGCTGGAG CCCCAACACA GTACCCACCA GGACGGGGCA CTCCGCCCCC ACCCGTCGGC
AGAGCAACCC CACCTCCAGG CATTATGGCT CCTCCACCTG GTATGAGACC ACCCATGGGC
CCACCAATTG GGCTTCCCCC TGCTCGAGGG ACGCCAATAG GCATGCCGCC TCCGGGAATG
AGACCCCCTC CACCAGGCAT TAGAGGTCCA CCTCCCCCAG GAATGCGTCC ACCAAGACCT
TAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu17081
Clone ID Related Accession (Same CDS sequence) NM_003097 , NM_022805 , NM_022806 , NM_022807 , NM_022808
Accession Version NM_022806.2 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 723bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product small nuclear ribonucleoprotein-associated protein N
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from U41303.1 and L80005.1. On Apr 4, 2003 this sequence version replaced gi:13027645. Transcript Variant: This variant (3) lacks exon 1 but utilizes upstream, non-coding exons u1B, u2 and u4. Alternative splicing takes place only in the 5' UTR, resulting in variants that all share exons 2-10, encoding identical proteins. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##RefSeq-Attributes-START## imprinted gene :: PMID: 7512861 ##RefSeq-Attributes-END## ##Evidence-Data-START## CDS exon combination :: L80004.1, BC000611.2 [ECO:0000331] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2144120 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

1
61
121
181
241
301
361
421
481
541
601
661
721
ATGACTGTTG GCAAGAGTAG CAAGATGCTG CAGCACATTG ACTATAGAAT GAGATGTATC 
CTGCAAGATG GCCGAATCTT CATTGGCACC TTTAAGGCTT TTGACAAGCA TATGAATTTG
ATCCTCTGTG ATTGTGATGA GTTCAGAAAG ATCAAGCCAA AGAATGCGAA GCAACCAGAG
CGTGAAGAAA AGCGGGTTTT GGGTCTGGTG TTGCTGCGTG GGGAGAACTT GGTATCCATG
ACTGTGGAGG GGCCACCCCC CAAAGATACT GGCATTGCTC GGGTACCACT TGCTGGAGCT
GCTGGAGGCC CTGGGGTTGG TAGGGCAGCT GGTAGAGGAG TACCAGCTGG TGTGCCAATT
CCCCAGGCCC CTGCTGGATT GGCAGGCCCT GTCCGAGGAG TTGGGGGACC ATCCCAGCAG
GTAATGACTC CACAGGGAAG AGGCACTGTA GCAGCTGCTG CTGTTGCTGC GACTGCCAGT
ATTGCTGGAG CCCCAACACA GTACCCACCA GGACGGGGCA CTCCGCCCCC ACCCGTCGGC
AGAGCAACCC CACCTCCAGG CATTATGGCT CCTCCACCTG GTATGAGACC ACCCATGGGC
CCACCAATTG GGCTTCCCCC TGCTCGAGGG ACGCCAATAG GCATGCCGCC TCCGGGAATG
AGACCCCCTC CACCAGGCAT TAGAGGTCCA CCTCCCCCAG GAATGCGTCC ACCAAGACCT
TAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_073717.1
CDS756..1478
Misc Feature(1)1..177(+)
Misc Feature(2)178..251(+)
Misc Feature(3)252..365(+)
Misc Feature(4)657..659(+)
Misc Feature(5)768..1004(+)
Misc Feature(6)777..1001(+)
Misc Feature(7)804..884(+)
Misc Feature(8)813..992(+)
Misc Feature(9)861..980(+)
Misc Feature(10)960..995(+)
Misc Feature(11)1278..1463(+)
Exon (1)1..177
Gene:SNRPN
Gene Synonym:
Exon (2)178..251
Gene:SNRPN
Gene Synonym:
Exon (3)252..365
Gene:SNRPN
Gene Synonym:
Exon (4)366..461
Gene:SNRPN
Gene Synonym:
Exon (5)462..612
Gene:SNRPN
Gene Synonym:
Exon (6)613..758
Gene:SNRPN
Gene Synonym:
Exon (7)759..910
Gene:SNRPN
Gene Synonym:
Exon (8)911..1022
Gene:SNRPN
Gene Synonym:
Exon (9)1023..1175
Gene:SNRPN
Gene Synonym:
Exon (10)1176..1314
Gene:SNRPN
Gene Synonym:
Exon (11)1315..1440
Gene:SNRPN
Gene Synonym:
Exon (12)1441..1616
Gene:SNRPN
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_022806
Organism Homo sapiens (human)
Definition Homo sapiens small nuclear ribonucleoprotein polypeptide N (SNRPN), transcript variant 3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_022806

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
ATGACTGTTG GCAAGAGTAG CAAGATGCTG CAGCACATTG ACTATAGAAT GAGATGTATC 
CTGCAAGATG GCCGAATCTT CATTGGCACC TTTAAGGCTT TTGACAAGCA TATGAATTTG
ATCCTCTGTG ATTGTGATGA GTTCAGAAAG ATCAAGCCAA AGAATGCGAA GCAACCAGAG
CGTGAAGAAA AGCGGGTTTT GGGTCTGGTG TTGCTGCGTG GGGAGAACTT GGTATCCATG
ACTGTGGAGG GGCCACCCCC CAAAGATACT GGCATTGCTC GGGTACCACT TGCTGGAGCT
GCTGGAGGCC CTGGGGTTGG TAGGGCAGCT GGTAGAGGAG TACCAGCTGG TGTGCCAATT
CCCCAGGCCC CTGCTGGATT GGCAGGCCCT GTCCGAGGAG TTGGGGGACC ATCCCAGCAG
GTAATGACTC CACAGGGAAG AGGCACTGTA GCAGCTGCTG CTGTTGCTGC GACTGCCAGT
ATTGCTGGAG CCCCAACACA GTACCCACCA GGACGGGGCA CTCCGCCCCC ACCCGTCGGC
AGAGCAACCC CACCTCCAGG CATTATGGCT CCTCCACCTG GTATGAGACC ACCCATGGGC
CCACCAATTG GGCTTCCCCC TGCTCGAGGG ACGCCAATAG GCATGCCGCC TCCGGGAATG
AGACCCCCTC CACCAGGCAT TAGAGGTCCA CCTCCCCCAG GAATGCGTCC ACCAAGACCT
TAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu17081
Clone ID Related Accession (Same CDS sequence) NM_003097 , NM_022805 , NM_022806 , NM_022807 , NM_022808
Accession Version NM_022807.2 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 723bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product small nuclear ribonucleoprotein-associated protein N
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from U41303.1 and L80005.1. This sequence is a reference standard in the RefSeqGene project. On Apr 4, 2003 this sequence version replaced gi:13027647. Transcript Variant: This variant (4) lacks exon 1 but utilizes upstream, non-coding exons u1B' (downstream alternative splice donor site for u1B), u1B*, u2 and u4. Alternative splicing takes place only in the 5' UTR, resulting in variants that all share exons 2-10, encoding identical proteins. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##RefSeq-Attributes-START## imprinted gene :: PMID: 7512861 ##RefSeq-Attributes-END## ##Evidence-Data-START## Transcript exon combination :: L80005.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA962337, SAMEA962346 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

1
61
121
181
241
301
361
421
481
541
601
661
721
ATGACTGTTG GCAAGAGTAG CAAGATGCTG CAGCACATTG ACTATAGAAT GAGATGTATC 
CTGCAAGATG GCCGAATCTT CATTGGCACC TTTAAGGCTT TTGACAAGCA TATGAATTTG
ATCCTCTGTG ATTGTGATGA GTTCAGAAAG ATCAAGCCAA AGAATGCGAA GCAACCAGAG
CGTGAAGAAA AGCGGGTTTT GGGTCTGGTG TTGCTGCGTG GGGAGAACTT GGTATCCATG
ACTGTGGAGG GGCCACCCCC CAAAGATACT GGCATTGCTC GGGTACCACT TGCTGGAGCT
GCTGGAGGCC CTGGGGTTGG TAGGGCAGCT GGTAGAGGAG TACCAGCTGG TGTGCCAATT
CCCCAGGCCC CTGCTGGATT GGCAGGCCCT GTCCGAGGAG TTGGGGGACC ATCCCAGCAG
GTAATGACTC CACAGGGAAG AGGCACTGTA GCAGCTGCTG CTGTTGCTGC GACTGCCAGT
ATTGCTGGAG CCCCAACACA GTACCCACCA GGACGGGGCA CTCCGCCCCC ACCCGTCGGC
AGAGCAACCC CACCTCCAGG CATTATGGCT CCTCCACCTG GTATGAGACC ACCCATGGGC
CCACCAATTG GGCTTCCCCC TGCTCGAGGG ACGCCAATAG GCATGCCGCC TCCGGGAATG
AGACCCCCTC CACCAGGCAT TAGAGGTCCA CCTCCCCCAG GAATGCGTCC ACCAAGACCT
TAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_073718.1
CDS891..1613
Misc Feature(1)1..204(+)
Misc Feature(2)205..312(+)
Misc Feature(3)313..386(+)
Misc Feature(4)387..500(+)
Misc Feature(5)792..794(+)
Misc Feature(6)903..1139(+)
Misc Feature(7)912..1136(+)
Misc Feature(8)939..1019(+)
Misc Feature(9)948..1127(+)
Misc Feature(10)996..1115(+)
Misc Feature(11)1095..1130(+)
Misc Feature(12)1413..1598(+)
Exon (1)1..204
Gene:SNRPN
Gene Synonym:
Exon (2)205..312
Gene:SNRPN
Gene Synonym:
Exon (3)313..386
Gene:SNRPN
Gene Synonym:
Exon (4)387..500
Gene:SNRPN
Gene Synonym:
Exon (5)501..596
Gene:SNRPN
Gene Synonym:
Exon (6)597..747
Gene:SNRPN
Gene Synonym:
Exon (7)748..893
Gene:SNRPN
Gene Synonym:
Exon (8)894..1045
Gene:SNRPN
Gene Synonym:
Exon (9)1046..1157
Gene:SNRPN
Gene Synonym:
Exon (10)1158..1310
Gene:SNRPN
Gene Synonym:
Exon (11)1311..1449
Gene:SNRPN
Gene Synonym:
Exon (12)1450..1575
Gene:SNRPN
Gene Synonym:
Exon (13)1576..1751
Gene:SNRPN
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_022807
Organism Homo sapiens (human)
Definition Homo sapiens small nuclear ribonucleoprotein polypeptide N (SNRPN), transcript variant 4, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_022807

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
ATGACTGTTG GCAAGAGTAG CAAGATGCTG CAGCACATTG ACTATAGAAT GAGATGTATC 
CTGCAAGATG GCCGAATCTT CATTGGCACC TTTAAGGCTT TTGACAAGCA TATGAATTTG
ATCCTCTGTG ATTGTGATGA GTTCAGAAAG ATCAAGCCAA AGAATGCGAA GCAACCAGAG
CGTGAAGAAA AGCGGGTTTT GGGTCTGGTG TTGCTGCGTG GGGAGAACTT GGTATCCATG
ACTGTGGAGG GGCCACCCCC CAAAGATACT GGCATTGCTC GGGTACCACT TGCTGGAGCT
GCTGGAGGCC CTGGGGTTGG TAGGGCAGCT GGTAGAGGAG TACCAGCTGG TGTGCCAATT
CCCCAGGCCC CTGCTGGATT GGCAGGCCCT GTCCGAGGAG TTGGGGGACC ATCCCAGCAG
GTAATGACTC CACAGGGAAG AGGCACTGTA GCAGCTGCTG CTGTTGCTGC GACTGCCAGT
ATTGCTGGAG CCCCAACACA GTACCCACCA GGACGGGGCA CTCCGCCCCC ACCCGTCGGC
AGAGCAACCC CACCTCCAGG CATTATGGCT CCTCCACCTG GTATGAGACC ACCCATGGGC
CCACCAATTG GGCTTCCCCC TGCTCGAGGG ACGCCAATAG GCATGCCGCC TCCGGGAATG
AGACCCCCTC CACCAGGCAT TAGAGGTCCA CCTCCCCCAG GAATGCGTCC ACCAAGACCT
TAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu17081
Clone ID Related Accession (Same CDS sequence) NM_003097 , NM_022805 , NM_022806 , NM_022807 , NM_022808
Accession Version NM_022808.2 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 723bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product small nuclear ribonucleoprotein-associated protein N
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from U41303.1 and L80005.1. On Apr 4, 2003 this sequence version replaced gi:13027649. Transcript Variant: This variant (5) lacks exon 1 but utilizes upstream, non-coding exons u1B' (downstream alternative splice donor site for u1B), u2 and u4. Alternative splicing takes place only in the 5' UTR, resulting in variants that all share exons 2-10, encoding identical proteins. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##RefSeq-Attributes-START## imprinted gene :: PMID: 7512861 ##RefSeq-Attributes-END## ##Evidence-Data-START## CDS exon combination :: L80004.1, BC000611.2 [ECO:0000331] RNAseq introns :: single sample supports all introns SAMEA2154665 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

1
61
121
181
241
301
361
421
481
541
601
661
721
ATGACTGTTG GCAAGAGTAG CAAGATGCTG CAGCACATTG ACTATAGAAT GAGATGTATC 
CTGCAAGATG GCCGAATCTT CATTGGCACC TTTAAGGCTT TTGACAAGCA TATGAATTTG
ATCCTCTGTG ATTGTGATGA GTTCAGAAAG ATCAAGCCAA AGAATGCGAA GCAACCAGAG
CGTGAAGAAA AGCGGGTTTT GGGTCTGGTG TTGCTGCGTG GGGAGAACTT GGTATCCATG
ACTGTGGAGG GGCCACCCCC CAAAGATACT GGCATTGCTC GGGTACCACT TGCTGGAGCT
GCTGGAGGCC CTGGGGTTGG TAGGGCAGCT GGTAGAGGAG TACCAGCTGG TGTGCCAATT
CCCCAGGCCC CTGCTGGATT GGCAGGCCCT GTCCGAGGAG TTGGGGGACC ATCCCAGCAG
GTAATGACTC CACAGGGAAG AGGCACTGTA GCAGCTGCTG CTGTTGCTGC GACTGCCAGT
ATTGCTGGAG CCCCAACACA GTACCCACCA GGACGGGGCA CTCCGCCCCC ACCCGTCGGC
AGAGCAACCC CACCTCCAGG CATTATGGCT CCTCCACCTG GTATGAGACC ACCCATGGGC
CCACCAATTG GGCTTCCCCC TGCTCGAGGG ACGCCAATAG GCATGCCGCC TCCGGGAATG
AGACCCCCTC CACCAGGCAT TAGAGGTCCA CCTCCCCCAG GAATGCGTCC ACCAAGACCT
TAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_073719.1
CDS783..1505
Misc Feature(1)1..204(+)
Misc Feature(2)205..278(+)
Misc Feature(3)279..392(+)
Misc Feature(4)684..686(+)
Misc Feature(5)795..1031(+)
Misc Feature(6)804..1028(+)
Misc Feature(7)831..911(+)
Misc Feature(8)840..1019(+)
Misc Feature(9)888..1007(+)
Misc Feature(10)987..1022(+)
Misc Feature(11)1305..1490(+)
Exon (1)1..204
Gene:SNRPN
Gene Synonym:
Exon (2)205..278
Gene:SNRPN
Gene Synonym:
Exon (3)279..392
Gene:SNRPN
Gene Synonym:
Exon (4)393..488
Gene:SNRPN
Gene Synonym:
Exon (5)489..639
Gene:SNRPN
Gene Synonym:
Exon (6)640..785
Gene:SNRPN
Gene Synonym:
Exon (7)786..937
Gene:SNRPN
Gene Synonym:
Exon (8)938..1049
Gene:SNRPN
Gene Synonym:
Exon (9)1050..1202
Gene:SNRPN
Gene Synonym:
Exon (10)1203..1341
Gene:SNRPN
Gene Synonym:
Exon (11)1342..1467
Gene:SNRPN
Gene Synonym:
Exon (12)1468..1643
Gene:SNRPN
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_022808
Organism Homo sapiens (human)
Definition Homo sapiens small nuclear ribonucleoprotein polypeptide N (SNRPN), transcript variant 5, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_022808

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
ATGACTGTTG GCAAGAGTAG CAAGATGCTG CAGCACATTG ACTATAGAAT GAGATGTATC 
CTGCAAGATG GCCGAATCTT CATTGGCACC TTTAAGGCTT TTGACAAGCA TATGAATTTG
ATCCTCTGTG ATTGTGATGA GTTCAGAAAG ATCAAGCCAA AGAATGCGAA GCAACCAGAG
CGTGAAGAAA AGCGGGTTTT GGGTCTGGTG TTGCTGCGTG GGGAGAACTT GGTATCCATG
ACTGTGGAGG GGCCACCCCC CAAAGATACT GGCATTGCTC GGGTACCACT TGCTGGAGCT
GCTGGAGGCC CTGGGGTTGG TAGGGCAGCT GGTAGAGGAG TACCAGCTGG TGTGCCAATT
CCCCAGGCCC CTGCTGGATT GGCAGGCCCT GTCCGAGGAG TTGGGGGACC ATCCCAGCAG
GTAATGACTC CACAGGGAAG AGGCACTGTA GCAGCTGCTG CTGTTGCTGC GACTGCCAGT
ATTGCTGGAG CCCCAACACA GTACCCACCA GGACGGGGCA CTCCGCCCCC ACCCGTCGGC
AGAGCAACCC CACCTCCAGG CATTATGGCT CCTCCACCTG GTATGAGACC ACCCATGGGC
CCACCAATTG GGCTTCCCCC TGCTCGAGGG ACGCCAATAG GCATGCCGCC TCCGGGAATG
AGACCCCCTC CACCAGGCAT TAGAGGTCCA CCTCCCCCAG GAATGCGTCC ACCAAGACCT
TAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

book

Protein interaction network of alternatively spliced isoforms from brain links genetic risk factors for autism
Nat Commun 5, 3650 (2014)
Corominas R, Yang X, Lin GN, Kang S, Shen Y, Ghamsari L, Broly M, Rodriguez M, Tam S, Trigg SA, Fan C, Yi S, Tasan M, Lemmens I, Kuang X, Zhao N, Malhotra D, Michaelson JJ, Vacic V, Calderwood MA, Roth FP, Tavernier J, Horvath S, Salehi-Ashtiani K, Korkin D, Sebat J, Hill DE, Hao T, Vidal M and Iakoucheva LM.


book

Genome-wide association study of chronic periodontitis in a general German population
J. Clin. Periodontol. 40 (11), 977-985 (2013)
Teumer A, Holtfreter B, Volker U, Petersmann A, Nauck M, Biffar R, Volzke H, Kroemer HK, Meisel P, Homuth G and Kocher T.


book

The IC-SNURF-SNRPN transcript serves as a host for multiple small nucleolar RNA species and as an antisense RNA for UBE3A
Hum. Mol. Genet. 10 (23), 2687-2700 (2001)
Runte M, Huttenhofer A, Gross S, Kiefmann M, Horsthemke B and Buiting K.


book

Prader-Willi syndrome is caused by disruption of the SNRPN gene
Am. J. Hum. Genet. 64 (1), 70-76 (1999)
Kuslich CD, Kobori JA, Mohapatra G, Gregorio-King C and Donlon TA.


book

Identification of novel exons 3' to the human SNRPN gene
Genomics 40 (1), 132-137 (1997)
Buiting K, Dittrich B, Endele S and Horsthemke B.


book

Maternal imprinting of human SNRPN, a gene deleted in Prader-Willi syndrome
Nat. Genet. 6 (2), 163-167 (1994)
Reed ML and Leff SE.


book

Autism Spectrum Disorders
(in) Pagon RA, Adam MP, Ardinger HH, Bird TD, Dolan CR, Fong CT, Smith RJH and Stephens K (Eds.); GENEREVIEWS(R); (1993)
Miles,J.H., McCathren,R.B., Stichter,J. and Shinawi,M.


book

Small nuclear ribonucleoprotein polypeptide N (SNRPN), an expressed gene in the Prader-Willi syndrome critical region
Nat. Genet. 2 (4), 265-269 (1992)
Ozcelik T, Leff S, Robinson W, Donlon T, Lalande M, Sanjines E, Schinzel A and Francke U.


book

The gene encoding the small nuclear ribonucleoprotein-associated protein N is expressed at high levels in neurons
J. Biol. Chem. 267 (12), 8521-8529 (1992)
Schmauss C, Brines ML and Lerner MR.


book

A comparison of snRNP-associated Sm-autoantigens: human N, rat N and human B/B'
Nucleic Acids Res. 17 (4), 1733-1743 (1989)
Schmauss C, McAllister G, Ohosone Y, Hardin JA and Lerner MR.


 
*
*
*
*