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SNRPN cDNA ORF clone, Homo sapiens (human)

Gene Symbol SNRPN
Entrez Gene ID 6638
Full Name small nuclear ribonucleoprotein polypeptide N
Synonyms HCERN3, PWCR, RT-LI, SM-D, SMN, SNRNP-N, SNURF-SNRPN, sm-N
General protein information
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

15

15q11.2

Summary The protein encoded by this gene is one polypeptide of a small nuclear ribonucleoprotein complex and belongs to the snRNP SMB/SMN family. The protein plays a role in pre-mRNA processing, possibly tissue-specific alternative splicing events. Although individual snRNPs are believed to recognize specific nucleic acid sequences through RNA-RNA base pairing, the specific role of this family member is unknown. The protein arises from a bicistronic transcript that also encodes a protein identified as the SNRPN upstream reading frame (SNURF). Multiple transcription initiation sites have been identified and extensive alternative splicing occurs in the 5' untranslated region. Additional splice variants have been described but sequences for the complete transcripts have not been determined. The 5' UTR of this gene has been identified as an imprinting center. Alternative splicing or deletion caused by a translocation event in this paternally-expressed region is responsible for Angelman syndrome or Prader-Willi syndrome due to parental imprint switch failure. [provided by RefSeq, Jul 2008]. lac of sum
Disorder MIM:

182279

Disorder Html: Prader-Willi syndrome, 176270 (3)





The following SNRPN gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SNRPN cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu17081 NM_003097 Homo sapiens small nuclear ribonucleoprotein polypeptide N (SNRPN), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$139.30
$199.00
OHu17081 NM_022805 Homo sapiens small nuclear ribonucleoprotein polypeptide N (SNRPN), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$139.30
$199.00
OHu17081 NM_022806 Homo sapiens small nuclear ribonucleoprotein polypeptide N (SNRPN), transcript variant 3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$139.30
$199.00
OHu17081 NM_022807 Homo sapiens small nuclear ribonucleoprotein polypeptide N (SNRPN), transcript variant 4, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$139.30
$199.00
OHu17081 NM_022808 Homo sapiens small nuclear ribonucleoprotein polypeptide N (SNRPN), transcript variant 5, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$139.30
$199.00

*Business Day
**You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.


CloneID OHu17081
Accession Version NM_003097.3 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 723bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product small nuclear ribonucleoprotein-associated protein N
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from X15892.1 and U41303.1. On or before Aug 31, 2013 this sequence version replaced gi:530405199, gi:169207847, gi:113425512, gi:13027651. Summary: The protein encoded by this gene is one polypeptide of a small nuclear ribonucleoprotein complex and belongs to the snRNP SMB/SMN family. The protein plays a role in pre-mRNA processing, possibly tissue-specific alternative splicing events. Although individual snRNPs are believed to recognize specific nucleic acid sequences through RNA-RNA base pairing, the specific role of this family member is unknown. The protein arises from a bicistronic transcript that also encodes a protein identified as the SNRPN upstream reading frame (SNURF). Multiple transcription initiation sites have been identified and extensive alternative splicing occurs in the 5' untranslated region. Additional splice variants have been described but sequences for the complete transcripts have not been determined. The 5' UTR of this gene has been identified as an imprinting center. Alternative splicing or deletion caused by a translocation event in this paternally-expressed region is responsible for Angelman syndrome or Prader-Willi syndrome due to parental imprint switch failure. [provided by RefSeq, Jul 2008]. Transcript Variant: This variant (1) utilizes alternative exon 1 and represents the predominant variant. Since this variant alone contains exon 1, it is the only one which also contains the complete open reading frame for SNURF. Alternative splicing takes place only in the 5' UTR, resulting in variants that all share exons 2-10, encoding identical proteins. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##RefSeq-Attributes-START## bicistronic transcript :: PMID: 10318933 imprinted gene :: PMID: 7512861 ##RefSeq-Attributes-END## ##Evidence-Data-START## Transcript exon combination :: U41303.1, BC018809.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

1
61
121
181
241
301
361
421
481
541
601
661
721
ATGACTGTTG GCAAGAGTAG CAAGATGCTG CAGCACATTG ACTATAGAAT GAGATGTATC 
CTGCAAGATG GCCGAATCTT CATTGGCACC TTTAAGGCTT TTGACAAGCA TATGAATTTG
ATCCTCTGTG ATTGTGATGA GTTCAGAAAG ATCAAGCCAA AGAATGCGAA GCAACCAGAG
CGTGAAGAAA AGCGGGTTTT GGGTCTGGTG TTGCTGCGTG GGGAGAACTT GGTATCCATG
ACTGTGGAGG GGCCACCCCC CAAAGATACT GGCATTGCTC GGGTACCACT TGCTGGAGCT
GCTGGAGGCC CTGGGGTTGG TAGGGCAGCT GGTAGAGGAG TACCAGCTGG TGTGCCAATT
CCCCAGGCCC CTGCTGGATT GGCAGGCCCT GTCCGAGGAG TTGGGGGACC ATCCCAGCAG
GTAATGACTC CACAGGGAAG AGGCACTGTA GCAGCTGCTG CTGTTGCTGC GACTGCCAGT
ATTGCTGGAG CCCCAACACA GTACCCACCA GGACGGGGCA CTCCGCCCCC ACCCGTCGGC
AGAGCAACCC CACCTCCAGG CATTATGGCT CCTCCACCTG GTATGAGACC ACCCATGGGC
CCACCAATTG GGCTTCCCCC TGCTCGAGGG ACGCCAATAG GCATGCCGCC TCCGGGAATG
AGACCCCCTC CACCAGGCAT TAGAGGTCCA CCTCCCCCAG GAATGCGTCC ACCAAGACCT
TAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeqNP_003088.1
CDS466..1188
Misc Feature(1)1..75(+)
Misc Feature(2)62..277(+)
Misc Feature(3)367..369(+)
Misc Feature(4)478..714(+)
Misc Feature(5)487..711(+)
Misc Feature(6)514..594(+)
Misc Feature(7)523..702(+)
Misc Feature(8)571..690(+)
Misc Feature(9)670..705(+)
Misc Feature(10)988..1173(+)
Exon (1)1..75
Gene:SNRPN
Gene Synonym:
Exon (2)76..171
Gene:SNRPN
Gene Synonym:
Exon (3)172..322
Gene:SNRPN
Gene Synonym:
Exon (4)323..468
Gene:SNRPN
Gene Synonym:
Exon (5)469..620
Gene:SNRPN
Gene Synonym:
Exon (6)621..732
Gene:SNRPN
Gene Synonym:
Exon (7)733..885
Gene:SNRPN
Gene Synonym:
Exon (8)886..1024
Gene:SNRPN
Gene Synonym:
Exon (9)1025..1150
Gene:SNRPN
Gene Synonym:
Exon (10)1151..1326
Gene:SNRPN
Gene Synonym:
Translation
Position Chain Variation Link
7 7 c, g dbSNP:541877352
12 12 a, g dbSNP:781581137
16 16 a, g dbSNP:370477576
18 18 c, t dbSNP:781381799
19 19 a, g dbSNP:375357277
25 25 g, t dbSNP:749365354
27 27 c, t dbSNP:563550744
28 28 a, t dbSNP:774303237
31 31 -, g dbSNP:756725184
31 31 c, g, t dbSNP:372506458
32 32 a, c, g, t dbSNP:199920294
33 33 c, t dbSNP:766021223
34 34 a, g dbSNP:546019816
35 35 c, t dbSNP:540110981
36 36 c, g, t dbSNP:368646285
38 38 a, g dbSNP:769799598
40 40 c, t dbSNP:781733715
48 48 c, g dbSNP:746205195
49 49 g, t dbSNP:756341117
53 53 a, c dbSNP:370974348
58 58 c, t dbSNP:148206963
60 60 c, g, t dbSNP:140138645
61 61 a, g, t dbSNP:749134956
72 72 c, g dbSNP:773029016
74 74 a, c dbSNP:760436951
78 78 a, g dbSNP:770705956
80 80 c, t dbSNP:776280755
88 88 c, t dbSNP:426541
96 96 a, g dbSNP:371527962
102 102 a, c dbSNP:779706602
106 106 a, g dbSNP:775190608
108 108 a, g dbSNP:762505215
112 112 c, t dbSNP:768170160
113 113 a, g dbSNP:199839388
130 130 a, c dbSNP:760960743
131 131 a, c dbSNP:11555312
134 134 g, t dbSNP:766822978
140 140 c, t dbSNP:754147955
141 141 a, g dbSNP:755265989
153 153 c, t dbSNP:779082047
165 165 a, g dbSNP:752792774
169 169 a, g dbSNP:376718476
170 170 a, g dbSNP:145306813
181 181 c, g dbSNP:755907959
184 184 c, t dbSNP:779865576
185 185 a, c dbSNP:758784397
186 186 c, t dbSNP:372295822
190 190 c, g dbSNP:148434270
191 191 c, t dbSNP:375510236
192 192 a, g, t dbSNP:142583293
193 193 c, t dbSNP:150955815
204 204 a, c, g dbSNP:765651266
207 207 a, g dbSNP:775831235
213 213 a, c dbSNP:763207021
215 215 a, g dbSNP:764282322
221 221 a, g dbSNP:751683227
224 224 c, t dbSNP:757200665
234 234 a, g dbSNP:781290013
235 235 a, g dbSNP:201516822
243 243 a, g dbSNP:767497295
246 246 c, t dbSNP:750271724
247 247 a, g, t dbSNP:200974605
259 259 c, g dbSNP:780059834
279 279 a, g dbSNP:749060545
281 281 c, t dbSNP:556831171
282 282 a, g dbSNP:778377202
284 284 a, g dbSNP:747719993
285 285 c, t dbSNP:115773942
289 289 a, g dbSNP:777204652
294 294 c, t dbSNP:372124469
296 296 a, g dbSNP:770257423
301 301 c, t dbSNP:369310410
305 305 a, g dbSNP:763259089
307 307 c, t dbSNP:768955159
310 310 a, t dbSNP:372969461
313 313 c, g dbSNP:774369656
325 325 c, t dbSNP:146374207
327 327 a, c dbSNP:3210366
330 330 c, g dbSNP:3210367
335 335 a, c dbSNP:11555010
356 356 g, t dbSNP:190439178
375 375 c, t dbSNP:557418874
377 377 c, t dbSNP:705
378 378 a, g dbSNP:201873312
385 385 a, c dbSNP:770742454
390 390 -, tatc dbSNP:772922093
426 426 a, c, g dbSNP:767553112
427 427 a, g dbSNP:75184959
434 434 c, g dbSNP:766395506
442 442 a, g dbSNP:199694871
446 446 g, t dbSNP:763736287
456 456 a, c, t dbSNP:368498622
465 465 c, t dbSNP:758068137
466 466 a, g dbSNP:777191177
472 472 a, g dbSNP:751103846
503 503 c, t dbSNP:756691188
510 510 -, t dbSNP:770445659
538 538 a, c dbSNP:780552612
539 539 a, g dbSNP:749853771
540 540 a, g dbSNP:567291118
547 547 a, t dbSNP:779184888
549 549 c, t dbSNP:748523454
567 567 g, t dbSNP:772205730
582 582 g, t dbSNP:377759095
591 591 c, t dbSNP:745944032
618 618 a, c dbSNP:747086080
620 620 a, g dbSNP:771074349
632 632 c, t dbSNP:571239725
633 633 a, g dbSNP:762669644
639 639 a, g dbSNP:763936171
646 646 c, g dbSNP:774128917
647 647 a, g dbSNP:761495657
648 648 c, t dbSNP:373215950
679 679 c, t dbSNP:749922581
683 683 a, g dbSNP:755610165
714 714 c, g dbSNP:765663018
720 720 a, g dbSNP:753186914
722 722 c, t dbSNP:758956901
723 723 c, t dbSNP:778345787
726 726 a, c, g, t dbSNP:200650114
732 732 c, t dbSNP:200092176
742 742 g, t dbSNP:200334709
750 750 a, g dbSNP:747941335
753 753 a, g dbSNP:771792556
765 765 c, t dbSNP:772865283
801 801 a, g dbSNP:760439672
805 805 g, t dbSNP:370688371
812 812 c, t dbSNP:200977523
813 813 c, t dbSNP:759079550
825 825 -, c dbSNP:34310223
827 827 c, t dbSNP:565012889
828 828 a, c dbSNP:142287541
830 830 a, c dbSNP:762396703
834 834 c, t dbSNP:767992679
873 873 a, t dbSNP:368006860
886 886 a, g dbSNP:777534123
892 892 a, t dbSNP:376675210
909 909 c, t dbSNP:746827268
910 910 a, g dbSNP:756947921
912 912 c, t dbSNP:781125322
919 919 -, gct dbSNP:761391559
927 927 a, t dbSNP:368621460
932 932 c, t dbSNP:372352489
935 935 c, t dbSNP:775190561
939 939 c, t dbSNP:1048231
943 943 a, g dbSNP:748700221
955 955 g, t dbSNP:772663663
961 961 a, g dbSNP:773523359
965 965 a, g dbSNP:761114054
970 970 c, t dbSNP:377153548
987 987 a, t dbSNP:776971923
990 990 a, g dbSNP:369947986
996 996 a, t dbSNP:765419900
997 997 c, g dbSNP:752794820
999 999 c, g, t dbSNP:35757423
1002 1002 c, t dbSNP:764108793
1003 1003 a, g dbSNP:374810704
1012 1012 a, g dbSNP:369210394
1014 1014 c, g dbSNP:781177011
1019 1019 c, t dbSNP:750225490
1021 1021 c, t dbSNP:71461576
1038 1038 c, t dbSNP:775919725
1041 1041 a, c dbSNP:763124504
1042 1042 c, g dbSNP:768904469
1043 1043 c, t dbSNP:774320395
1053 1053 a, g dbSNP:761947143
1059 1059 c, t dbSNP:767568767
1067 1067 c, t dbSNP:773223686
1071 1071 a, c dbSNP:760673179
1077 1077 g, t dbSNP:766149753
1089 1089 c, g, t dbSNP:200487846
1097 1097 c, t dbSNP:764893207
1098 1098 a, g dbSNP:372752818
1102 1102 a, g dbSNP:762574002
1112 1112 c, t dbSNP:777253872
1113 1113 a, g dbSNP:746441330
1122 1122 a, g dbSNP:375488054
1129 1129 c, t dbSNP:780336659
1146 1146 g, t dbSNP:749619229
1156 1156 c, t dbSNP:199833583
1173 1173 a, t dbSNP:755315127
1201 1201 c, g, t dbSNP:376058438
1203 1203 a, c dbSNP:772389635
1207 1207 c, g dbSNP:773471460
1208 1208 a, t dbSNP:747036997
1211 1211 c, t dbSNP:770805478
1212 1212 a, t dbSNP:369397502
1213 1213 c, g, t dbSNP:112904440
1215 1215 g, t dbSNP:759379892
1221 1221 c, t dbSNP:374839284
1227 1227 a, g dbSNP:554720050
1229 1229 a, g dbSNP:775235918
1230 1230 c, t dbSNP:762643841
1231 1231 a, g dbSNP:189125295
1237 1237 c, t dbSNP:751103806
1253 1253 a, g dbSNP:537311445
1316 1316 a, g dbSNP:143504129
1322 1322 c, t dbSNP:2732052

Target ORF information:

RefSeq Version NM_003097
Organism Homo sapiens (human)
Definition Homo sapiens small nuclear ribonucleoprotein polypeptide N (SNRPN), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_003097

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
ATGACTGTTG GCAAGAGTAG CAAGATGCTG CAGCACATTG ACTATAGAAT GAGATGTATC 
CTGCAAGATG GCCGAATCTT CATTGGCACC TTTAAGGCTT TTGACAAGCA TATGAATTTG
ATCCTCTGTG ATTGTGATGA GTTCAGAAAG ATCAAGCCAA AGAATGCGAA GCAACCAGAG
CGTGAAGAAA AGCGGGTTTT GGGTCTGGTG TTGCTGCGTG GGGAGAACTT GGTATCCATG
ACTGTGGAGG GGCCACCCCC CAAAGATACT GGCATTGCTC GGGTACCACT TGCTGGAGCT
GCTGGAGGCC CTGGGGTTGG TAGGGCAGCT GGTAGAGGAG TACCAGCTGG TGTGCCAATT
CCCCAGGCCC CTGCTGGATT GGCAGGCCCT GTCCGAGGAG TTGGGGGACC ATCCCAGCAG
GTAATGACTC CACAGGGAAG AGGCACTGTA GCAGCTGCTG CTGTTGCTGC GACTGCCAGT
ATTGCTGGAG CCCCAACACA GTACCCACCA GGACGGGGCA CTCCGCCCCC ACCCGTCGGC
AGAGCAACCC CACCTCCAGG CATTATGGCT CCTCCACCTG GTATGAGACC ACCCATGGGC
CCACCAATTG GGCTTCCCCC TGCTCGAGGG ACGCCAATAG GCATGCCGCC TCCGGGAATG
AGACCCCCTC CACCAGGCAT TAGAGGTCCA CCTCCCCCAG GAATGCGTCC ACCAAGACCT
TAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu17081
Accession Version NM_022805.2 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 723bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product small nuclear ribonucleoprotein-associated protein N
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from U41303.1 and L80004.1. On Apr 4, 2003 this sequence version replaced gi:13027643. Summary: The protein encoded by this gene is one polypeptide of a small nuclear ribonucleoprotein complex and belongs to the snRNP SMB/SMN family. The protein plays a role in pre-mRNA processing, possibly tissue-specific alternative splicing events. Although individual snRNPs are believed to recognize specific nucleic acid sequences through RNA-RNA base pairing, the specific role of this family member is unknown. The protein arises from a bicistronic transcript that also encodes a protein identified as the SNRPN upstream reading frame (SNURF). Multiple transcription initiation sites have been identified and extensive alternative splicing occurs in the 5' untranslated region. Additional splice variants have been described but sequences for the complete transcripts have not been determined. The 5' UTR of this gene has been identified as an imprinting center. Alternative splicing or deletion caused by a translocation event in this paternally-expressed region is responsible for Angelman syndrome or Prader-Willi syndrome due to parental imprint switch failure. [provided by RefSeq, Jul 2008]. Transcript Variant: This variant (2) lacks exon 1 but utilizes upstream, non-coding exons u1A, u2 and u4. Alternative splicing takes place only in the 5' UTR, resulting in variants that all share exons 2-10, encoding identical proteins. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##RefSeq-Attributes-START## imprinted gene :: PMID: 7512861 ##RefSeq-Attributes-END## ##Evidence-Data-START## Transcript exon combination :: L80004.1, AK222633.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2144335 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

1
61
121
181
241
301
361
421
481
541
601
661
721
ATGACTGTTG GCAAGAGTAG CAAGATGCTG CAGCACATTG ACTATAGAAT GAGATGTATC 
CTGCAAGATG GCCGAATCTT CATTGGCACC TTTAAGGCTT TTGACAAGCA TATGAATTTG
ATCCTCTGTG ATTGTGATGA GTTCAGAAAG ATCAAGCCAA AGAATGCGAA GCAACCAGAG
CGTGAAGAAA AGCGGGTTTT GGGTCTGGTG TTGCTGCGTG GGGAGAACTT GGTATCCATG
ACTGTGGAGG GGCCACCCCC CAAAGATACT GGCATTGCTC GGGTACCACT TGCTGGAGCT
GCTGGAGGCC CTGGGGTTGG TAGGGCAGCT GGTAGAGGAG TACCAGCTGG TGTGCCAATT
CCCCAGGCCC CTGCTGGATT GGCAGGCCCT GTCCGAGGAG TTGGGGGACC ATCCCAGCAG
GTAATGACTC CACAGGGAAG AGGCACTGTA GCAGCTGCTG CTGTTGCTGC GACTGCCAGT
ATTGCTGGAG CCCCAACACA GTACCCACCA GGACGGGGCA CTCCGCCCCC ACCCGTCGGC
AGAGCAACCC CACCTCCAGG CATTATGGCT CCTCCACCTG GTATGAGACC ACCCATGGGC
CCACCAATTG GGCTTCCCCC TGCTCGAGGG ACGCCAATAG GCATGCCGCC TCCGGGAATG
AGACCCCCTC CACCAGGCAT TAGAGGTCCA CCTCCCCCAG GAATGCGTCC ACCAAGACCT
TAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeqNP_073716.1
CDS745..1467
Misc Feature(1)1..166(+)
Misc Feature(2)167..240(+)
Misc Feature(3)241..354(+)
Misc Feature(4)646..648(+)
Misc Feature(5)757..993(+)
Misc Feature(6)766..990(+)
Misc Feature(7)793..873(+)
Misc Feature(8)802..981(+)
Misc Feature(9)850..969(+)
Misc Feature(10)949..984(+)
Misc Feature(11)1267..1452(+)
Exon (1)1..166
Gene:SNRPN
Gene Synonym:
Exon (2)167..240
Gene:SNRPN
Gene Synonym:
Exon (3)241..354
Gene:SNRPN
Gene Synonym:
Exon (4)355..450
Gene:SNRPN
Gene Synonym:
Exon (5)451..601
Gene:SNRPN
Gene Synonym:
Exon (6)602..747
Gene:SNRPN
Gene Synonym:
Exon (7)748..899
Gene:SNRPN
Gene Synonym:
Exon (8)900..1011
Gene:SNRPN
Gene Synonym:
Exon (9)1012..1164
Gene:SNRPN
Gene Synonym:
Exon (10)1165..1303
Gene:SNRPN
Gene Synonym:
Exon (11)1304..1429
Gene:SNRPN
Gene Synonym:
Exon (12)1430..1605
Gene:SNRPN
Gene Synonym:
Translation
Position Chain Variation Link
7 7 a, g dbSNP:61159950
53 53 -, ct dbSNP:566898641
66 66 a, g dbSNP:778919662
96 96 a, g dbSNP:540775620
131 131 c, t dbSNP:142805794
141 141 a, g dbSNP:752873
145 145 c, t dbSNP:758138656
161 161 c, t dbSNP:558839901
176 176 c, t dbSNP:80135925
191 191 a, c dbSNP:531664883
224 224 a, c, g dbSNP:550112116
240 240 c, g dbSNP:565041964
272 272 c, t dbSNP:571418891
280 280 a, t dbSNP:115572613
321 321 c, t dbSNP:547200109
349 349 c, t dbSNP:565390737
357 357 a, g dbSNP:770705956
359 359 c, t dbSNP:776280755
367 367 c, t dbSNP:426541
375 375 a, g dbSNP:371527962
381 381 a, c dbSNP:779706602
385 385 a, g dbSNP:775190608
387 387 a, g dbSNP:762505215
391 391 c, t dbSNP:768170160
392 392 a, g dbSNP:199839388
409 409 a, c dbSNP:760960743
410 410 a, c dbSNP:11555312
413 413 g, t dbSNP:766822978
419 419 c, t dbSNP:754147955
420 420 a, g dbSNP:755265989
432 432 c, t dbSNP:779082047
444 444 a, g dbSNP:752792774
448 448 a, g dbSNP:376718476
449 449 a, g dbSNP:145306813
460 460 c, g dbSNP:755907959
463 463 c, t dbSNP:779865576
464 464 a, c dbSNP:758784397
465 465 c, t dbSNP:372295822
469 469 c, g dbSNP:148434270
470 470 c, t dbSNP:375510236
471 471 a, g, t dbSNP:142583293
472 472 c, t dbSNP:150955815
483 483 a, c, g dbSNP:765651266
486 486 a, g dbSNP:775831235
492 492 a, c dbSNP:763207021
494 494 a, g dbSNP:764282322
500 500 a, g dbSNP:751683227
503 503 c, t dbSNP:757200665
513 513 a, g dbSNP:781290013
514 514 a, g dbSNP:201516822
522 522 a, g dbSNP:767497295
525 525 c, t dbSNP:750271724
526 526 a, g, t dbSNP:200974605
538 538 c, g dbSNP:780059834
558 558 a, g dbSNP:749060545
560 560 c, t dbSNP:556831171
561 561 a, g dbSNP:778377202
563 563 a, g dbSNP:747719993
564 564 c, t dbSNP:115773942
568 568 a, g dbSNP:777204652
573 573 c, t dbSNP:372124469
575 575 a, g dbSNP:770257423
580 580 c, t dbSNP:369310410
584 584 a, g dbSNP:763259089
586 586 c, t dbSNP:768955159
589 589 a, t dbSNP:372969461
592 592 c, g dbSNP:774369656
604 604 c, t dbSNP:146374207
606 606 a, c dbSNP:3210366
609 609 c, g dbSNP:3210367
614 614 a, c dbSNP:11555010
635 635 g, t dbSNP:190439178
654 654 c, t dbSNP:557418874
656 656 c, t dbSNP:705
657 657 a, g dbSNP:201873312
664 664 a, c dbSNP:770742454
669 669 -, tatc dbSNP:772922093
705 705 a, c, g dbSNP:767553112
706 706 a, g dbSNP:75184959
713 713 c, g dbSNP:766395506
721 721 a, g dbSNP:199694871
725 725 g, t dbSNP:763736287
735 735 a, c, t dbSNP:368498622
744 744 c, t dbSNP:758068137
745 745 a, g dbSNP:777191177
751 751 a, g dbSNP:751103846
782 782 c, t dbSNP:756691188
789 789 -, t dbSNP:770445659
817 817 a, c dbSNP:780552612
818 818 a, g dbSNP:749853771
819 819 a, g dbSNP:567291118
826 826 a, t dbSNP:779184888
828 828 c, t dbSNP:748523454
846 846 g, t dbSNP:772205730
861 861 g, t dbSNP:377759095
870 870 c, t dbSNP:745944032
897 897 a, c dbSNP:747086080
899 899 a, g dbSNP:771074349
911 911 c, t dbSNP:571239725
912 912 a, g dbSNP:762669644
918 918 a, g dbSNP:763936171
925 925 c, g dbSNP:774128917
926 926 a, g dbSNP:761495657
927 927 c, t dbSNP:373215950
958 958 c, t dbSNP:749922581
962 962 a, g dbSNP:755610165
993 993 c, g dbSNP:765663018
999 999 a, g dbSNP:753186914
1001 1001 c, t dbSNP:758956901
1002 1002 c, t dbSNP:778345787
1005 1005 a, c, g, t dbSNP:200650114
1011 1011 c, t dbSNP:200092176
1021 1021 g, t dbSNP:200334709
1029 1029 a, g dbSNP:747941335
1032 1032 a, g dbSNP:771792556
1044 1044 c, t dbSNP:772865283
1080 1080 a, g dbSNP:760439672
1084 1084 g, t dbSNP:370688371
1091 1091 c, t dbSNP:200977523
1092 1092 c, t dbSNP:759079550
1104 1104 -, c dbSNP:34310223
1106 1106 c, t dbSNP:565012889
1107 1107 a, c dbSNP:142287541
1109 1109 a, c dbSNP:762396703
1113 1113 c, t dbSNP:767992679
1152 1152 a, t dbSNP:368006860
1165 1165 a, g dbSNP:777534123
1171 1171 a, t dbSNP:376675210
1188 1188 c, t dbSNP:746827268
1189 1189 a, g dbSNP:756947921
1191 1191 c, t dbSNP:781125322
1198 1198 -, gct dbSNP:761391559
1206 1206 a, t dbSNP:368621460
1211 1211 c, t dbSNP:372352489
1214 1214 c, t dbSNP:775190561
1218 1218 c, t dbSNP:1048231
1222 1222 a, g dbSNP:748700221
1234 1234 g, t dbSNP:772663663
1240 1240 a, g dbSNP:773523359
1244 1244 a, g dbSNP:761114054
1249 1249 c, t dbSNP:377153548
1266 1266 a, t dbSNP:776971923
1269 1269 a, g dbSNP:369947986
1275 1275 a, t dbSNP:765419900
1276 1276 c, g dbSNP:752794820
1278 1278 c, g, t dbSNP:35757423
1281 1281 c, t dbSNP:764108793
1282 1282 a, g dbSNP:374810704
1291 1291 a, g dbSNP:369210394
1293 1293 c, g dbSNP:781177011
1298 1298 c, t dbSNP:750225490
1300 1300 c, t dbSNP:71461576
1317 1317 c, t dbSNP:775919725
1320 1320 a, c dbSNP:763124504
1321 1321 c, g dbSNP:768904469
1322 1322 c, t dbSNP:774320395
1332 1332 a, g dbSNP:761947143
1338 1338 c, t dbSNP:767568767
1346 1346 c, t dbSNP:773223686
1350 1350 a, c dbSNP:760673179
1356 1356 g, t dbSNP:766149753
1368 1368 c, g, t dbSNP:200487846
1376 1376 c, t dbSNP:764893207
1377 1377 a, g dbSNP:372752818
1381 1381 a, g dbSNP:762574002
1391 1391 c, t dbSNP:777253872
1392 1392 a, g dbSNP:746441330
1401 1401 a, g dbSNP:375488054
1408 1408 c, t dbSNP:780336659
1425 1425 g, t dbSNP:749619229
1435 1435 c, t dbSNP:199833583
1452 1452 a, t dbSNP:755315127
1480 1480 c, g, t dbSNP:376058438
1482 1482 a, c dbSNP:772389635
1486 1486 c, g dbSNP:773471460
1487 1487 a, t dbSNP:747036997
1490 1490 c, t dbSNP:770805478
1491 1491 a, t dbSNP:369397502
1492 1492 c, g, t dbSNP:112904440
1494 1494 g, t dbSNP:759379892
1500 1500 c, t dbSNP:374839284
1506 1506 a, g dbSNP:554720050
1508 1508 a, g dbSNP:775235918
1509 1509 c, t dbSNP:762643841
1510 1510 a, g dbSNP:189125295
1516 1516 c, t dbSNP:751103806
1532 1532 a, g dbSNP:537311445
1595 1595 a, g dbSNP:143504129
1601 1601 c, t dbSNP:2732052

Target ORF information:

RefSeq Version NM_022805
Organism Homo sapiens (human)
Definition Homo sapiens small nuclear ribonucleoprotein polypeptide N (SNRPN), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_022805

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
ATGACTGTTG GCAAGAGTAG CAAGATGCTG CAGCACATTG ACTATAGAAT GAGATGTATC 
CTGCAAGATG GCCGAATCTT CATTGGCACC TTTAAGGCTT TTGACAAGCA TATGAATTTG
ATCCTCTGTG ATTGTGATGA GTTCAGAAAG ATCAAGCCAA AGAATGCGAA GCAACCAGAG
CGTGAAGAAA AGCGGGTTTT GGGTCTGGTG TTGCTGCGTG GGGAGAACTT GGTATCCATG
ACTGTGGAGG GGCCACCCCC CAAAGATACT GGCATTGCTC GGGTACCACT TGCTGGAGCT
GCTGGAGGCC CTGGGGTTGG TAGGGCAGCT GGTAGAGGAG TACCAGCTGG TGTGCCAATT
CCCCAGGCCC CTGCTGGATT GGCAGGCCCT GTCCGAGGAG TTGGGGGACC ATCCCAGCAG
GTAATGACTC CACAGGGAAG AGGCACTGTA GCAGCTGCTG CTGTTGCTGC GACTGCCAGT
ATTGCTGGAG CCCCAACACA GTACCCACCA GGACGGGGCA CTCCGCCCCC ACCCGTCGGC
AGAGCAACCC CACCTCCAGG CATTATGGCT CCTCCACCTG GTATGAGACC ACCCATGGGC
CCACCAATTG GGCTTCCCCC TGCTCGAGGG ACGCCAATAG GCATGCCGCC TCCGGGAATG
AGACCCCCTC CACCAGGCAT TAGAGGTCCA CCTCCCCCAG GAATGCGTCC ACCAAGACCT
TAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu17081
Accession Version NM_022806.2 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 723bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product small nuclear ribonucleoprotein-associated protein N
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from U41303.1 and L80005.1. On Apr 4, 2003 this sequence version replaced gi:13027645. Summary: The protein encoded by this gene is one polypeptide of a small nuclear ribonucleoprotein complex and belongs to the snRNP SMB/SMN family. The protein plays a role in pre-mRNA processing, possibly tissue-specific alternative splicing events. Although individual snRNPs are believed to recognize specific nucleic acid sequences through RNA-RNA base pairing, the specific role of this family member is unknown. The protein arises from a bicistronic transcript that also encodes a protein identified as the SNRPN upstream reading frame (SNURF). Multiple transcription initiation sites have been identified and extensive alternative splicing occurs in the 5' untranslated region. Additional splice variants have been described but sequences for the complete transcripts have not been determined. The 5' UTR of this gene has been identified as an imprinting center. Alternative splicing or deletion caused by a translocation event in this paternally-expressed region is responsible for Angelman syndrome or Prader-Willi syndrome due to parental imprint switch failure. [provided by RefSeq, Jul 2008]. Transcript Variant: This variant (3) lacks exon 1 but utilizes upstream, non-coding exons u1B, u2 and u4. Alternative splicing takes place only in the 5' UTR, resulting in variants that all share exons 2-10, encoding identical proteins. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##RefSeq-Attributes-START## imprinted gene :: PMID: 7512861 ##RefSeq-Attributes-END## ##Evidence-Data-START## CDS exon combination :: L80004.1, BC000611.2 [ECO:0000331] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2144120 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

1
61
121
181
241
301
361
421
481
541
601
661
721
ATGACTGTTG GCAAGAGTAG CAAGATGCTG CAGCACATTG ACTATAGAAT GAGATGTATC 
CTGCAAGATG GCCGAATCTT CATTGGCACC TTTAAGGCTT TTGACAAGCA TATGAATTTG
ATCCTCTGTG ATTGTGATGA GTTCAGAAAG ATCAAGCCAA AGAATGCGAA GCAACCAGAG
CGTGAAGAAA AGCGGGTTTT GGGTCTGGTG TTGCTGCGTG GGGAGAACTT GGTATCCATG
ACTGTGGAGG GGCCACCCCC CAAAGATACT GGCATTGCTC GGGTACCACT TGCTGGAGCT
GCTGGAGGCC CTGGGGTTGG TAGGGCAGCT GGTAGAGGAG TACCAGCTGG TGTGCCAATT
CCCCAGGCCC CTGCTGGATT GGCAGGCCCT GTCCGAGGAG TTGGGGGACC ATCCCAGCAG
GTAATGACTC CACAGGGAAG AGGCACTGTA GCAGCTGCTG CTGTTGCTGC GACTGCCAGT
ATTGCTGGAG CCCCAACACA GTACCCACCA GGACGGGGCA CTCCGCCCCC ACCCGTCGGC
AGAGCAACCC CACCTCCAGG CATTATGGCT CCTCCACCTG GTATGAGACC ACCCATGGGC
CCACCAATTG GGCTTCCCCC TGCTCGAGGG ACGCCAATAG GCATGCCGCC TCCGGGAATG
AGACCCCCTC CACCAGGCAT TAGAGGTCCA CCTCCCCCAG GAATGCGTCC ACCAAGACCT
TAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeqNP_073717.1
CDS756..1478
Misc Feature(1)1..177(+)
Misc Feature(2)178..251(+)
Misc Feature(3)252..365(+)
Misc Feature(4)657..659(+)
Misc Feature(5)768..1004(+)
Misc Feature(6)777..1001(+)
Misc Feature(7)804..884(+)
Misc Feature(8)813..992(+)
Misc Feature(9)861..980(+)
Misc Feature(10)960..995(+)
Misc Feature(11)1278..1463(+)
Exon (1)1..177
Gene:SNRPN
Gene Synonym:
Exon (2)178..251
Gene:SNRPN
Gene Synonym:
Exon (3)252..365
Gene:SNRPN
Gene Synonym:
Exon (4)366..461
Gene:SNRPN
Gene Synonym:
Exon (5)462..612
Gene:SNRPN
Gene Synonym:
Exon (6)613..758
Gene:SNRPN
Gene Synonym:
Exon (7)759..910
Gene:SNRPN
Gene Synonym:
Exon (8)911..1022
Gene:SNRPN
Gene Synonym:
Exon (9)1023..1175
Gene:SNRPN
Gene Synonym:
Exon (10)1176..1314
Gene:SNRPN
Gene Synonym:
Exon (11)1315..1440
Gene:SNRPN
Gene Synonym:
Exon (12)1441..1616
Gene:SNRPN
Gene Synonym:
Translation
Position Chain Variation Link
1 1 a, c dbSNP:531983841
20 20 c, t dbSNP:746318333
29 29 c, g dbSNP:145889115
40 40 a, g dbSNP:567196678
44 44 g, t dbSNP:74005355
51 51 g, t dbSNP:145814686
74 74 a, g dbSNP:146599298
77 77 c, t dbSNP:753201810
94 94 g, t dbSNP:567787688
110 110 c, t dbSNP:538301088
156 156 a, g dbSNP:181347216
187 187 c, t dbSNP:80135925
202 202 a, c dbSNP:531664883
235 235 a, c, g dbSNP:550112116
251 251 c, g dbSNP:565041964
283 283 c, t dbSNP:571418891
291 291 a, t dbSNP:115572613
332 332 c, t dbSNP:547200109
360 360 c, t dbSNP:565390737
368 368 a, g dbSNP:770705956
370 370 c, t dbSNP:776280755
378 378 c, t dbSNP:426541
386 386 a, g dbSNP:371527962
392 392 a, c dbSNP:779706602
396 396 a, g dbSNP:775190608
398 398 a, g dbSNP:762505215
402 402 c, t dbSNP:768170160
403 403 a, g dbSNP:199839388
420 420 a, c dbSNP:760960743
421 421 a, c dbSNP:11555312
424 424 g, t dbSNP:766822978
430 430 c, t dbSNP:754147955
431 431 a, g dbSNP:755265989
443 443 c, t dbSNP:779082047
455 455 a, g dbSNP:752792774
459 459 a, g dbSNP:376718476
460 460 a, g dbSNP:145306813
471 471 c, g dbSNP:755907959
474 474 c, t dbSNP:779865576
475 475 a, c dbSNP:758784397
476 476 c, t dbSNP:372295822
480 480 c, g dbSNP:148434270
481 481 c, t dbSNP:375510236
482 482 a, g, t dbSNP:142583293
483 483 c, t dbSNP:150955815
494 494 a, c, g dbSNP:765651266
497 497 a, g dbSNP:775831235
503 503 a, c dbSNP:763207021
505 505 a, g dbSNP:764282322
511 511 a, g dbSNP:751683227
514 514 c, t dbSNP:757200665
524 524 a, g dbSNP:781290013
525 525 a, g dbSNP:201516822
533 533 a, g dbSNP:767497295
536 536 c, t dbSNP:750271724
537 537 a, g, t dbSNP:200974605
549 549 c, g dbSNP:780059834
569 569 a, g dbSNP:749060545
571 571 c, t dbSNP:556831171
572 572 a, g dbSNP:778377202
574 574 a, g dbSNP:747719993
575 575 c, t dbSNP:115773942
579 579 a, g dbSNP:777204652
584 584 c, t dbSNP:372124469
586 586 a, g dbSNP:770257423
591 591 c, t dbSNP:369310410
595 595 a, g dbSNP:763259089
597 597 c, t dbSNP:768955159
600 600 a, t dbSNP:372969461
603 603 c, g dbSNP:774369656
615 615 c, t dbSNP:146374207
617 617 a, c dbSNP:3210366
620 620 c, g dbSNP:3210367
625 625 a, c dbSNP:11555010
646 646 g, t dbSNP:190439178
665 665 c, t dbSNP:557418874
667 667 c, t dbSNP:705
668 668 a, g dbSNP:201873312
675 675 a, c dbSNP:770742454
680 680 -, tatc dbSNP:772922093
716 716 a, c, g dbSNP:767553112
717 717 a, g dbSNP:75184959
724 724 c, g dbSNP:766395506
732 732 a, g dbSNP:199694871
736 736 g, t dbSNP:763736287
746 746 a, c, t dbSNP:368498622
755 755 c, t dbSNP:758068137
756 756 a, g dbSNP:777191177
762 762 a, g dbSNP:751103846
793 793 c, t dbSNP:756691188
800 800 -, t dbSNP:770445659
828 828 a, c dbSNP:780552612
829 829 a, g dbSNP:749853771
830 830 a, g dbSNP:567291118
837 837 a, t dbSNP:779184888
839 839 c, t dbSNP:748523454
857 857 g, t dbSNP:772205730
872 872 g, t dbSNP:377759095
881 881 c, t dbSNP:745944032
908 908 a, c dbSNP:747086080
910 910 a, g dbSNP:771074349
922 922 c, t dbSNP:571239725
923 923 a, g dbSNP:762669644
929 929 a, g dbSNP:763936171
936 936 c, g dbSNP:774128917
937 937 a, g dbSNP:761495657
938 938 c, t dbSNP:373215950
969 969 c, t dbSNP:749922581
973 973 a, g dbSNP:755610165
1004 1004 c, g dbSNP:765663018
1010 1010 a, g dbSNP:753186914
1012 1012 c, t dbSNP:758956901
1013 1013 c, t dbSNP:778345787
1016 1016 a, c, g, t dbSNP:200650114
1022 1022 c, t dbSNP:200092176
1032 1032 g, t dbSNP:200334709
1040 1040 a, g dbSNP:747941335
1043 1043 a, g dbSNP:771792556
1055 1055 c, t dbSNP:772865283
1091 1091 a, g dbSNP:760439672
1095 1095 g, t dbSNP:370688371
1102 1102 c, t dbSNP:200977523
1103 1103 c, t dbSNP:759079550
1115 1115 -, c dbSNP:34310223
1117 1117 c, t dbSNP:565012889
1118 1118 a, c dbSNP:142287541
1120 1120 a, c dbSNP:762396703
1124 1124 c, t dbSNP:767992679
1163 1163 a, t dbSNP:368006860
1176 1176 a, g dbSNP:777534123
1182 1182 a, t dbSNP:376675210
1199 1199 c, t dbSNP:746827268
1200 1200 a, g dbSNP:756947921
1202 1202 c, t dbSNP:781125322
1209 1209 -, gct dbSNP:761391559
1217 1217 a, t dbSNP:368621460
1222 1222 c, t dbSNP:372352489
1225 1225 c, t dbSNP:775190561
1229 1229 c, t dbSNP:1048231
1233 1233 a, g dbSNP:748700221
1245 1245 g, t dbSNP:772663663
1251 1251 a, g dbSNP:773523359
1255 1255 a, g dbSNP:761114054
1260 1260 c, t dbSNP:377153548
1277 1277 a, t dbSNP:776971923
1280 1280 a, g dbSNP:369947986
1286 1286 a, t dbSNP:765419900
1287 1287 c, g dbSNP:752794820
1289 1289 c, g, t dbSNP:35757423
1292 1292 c, t dbSNP:764108793
1293 1293 a, g dbSNP:374810704
1302 1302 a, g dbSNP:369210394
1304 1304 c, g dbSNP:781177011
1309 1309 c, t dbSNP:750225490
1311 1311 c, t dbSNP:71461576
1328 1328 c, t dbSNP:775919725
1331 1331 a, c dbSNP:763124504
1332 1332 c, g dbSNP:768904469
1333 1333 c, t dbSNP:774320395
1343 1343 a, g dbSNP:761947143
1349 1349 c, t dbSNP:767568767
1357 1357 c, t dbSNP:773223686
1361 1361 a, c dbSNP:760673179
1367 1367 g, t dbSNP:766149753
1379 1379 c, g, t dbSNP:200487846
1387 1387 c, t dbSNP:764893207
1388 1388 a, g dbSNP:372752818
1392 1392 a, g dbSNP:762574002
1402 1402 c, t dbSNP:777253872
1403 1403 a, g dbSNP:746441330
1412 1412 a, g dbSNP:375488054
1419 1419 c, t dbSNP:780336659
1436 1436 g, t dbSNP:749619229
1446 1446 c, t dbSNP:199833583
1463 1463 a, t dbSNP:755315127
1491 1491 c, g, t dbSNP:376058438
1493 1493 a, c dbSNP:772389635
1497 1497 c, g dbSNP:773471460
1498 1498 a, t dbSNP:747036997
1501 1501 c, t dbSNP:770805478
1502 1502 a, t dbSNP:369397502
1503 1503 c, g, t dbSNP:112904440
1505 1505 g, t dbSNP:759379892
1511 1511 c, t dbSNP:374839284
1517 1517 a, g dbSNP:554720050
1519 1519 a, g dbSNP:775235918
1520 1520 c, t dbSNP:762643841
1521 1521 a, g dbSNP:189125295
1527 1527 c, t dbSNP:751103806
1543 1543 a, g dbSNP:537311445
1606 1606 a, g dbSNP:143504129
1612 1612 c, t dbSNP:2732052

Target ORF information:

RefSeq Version NM_022806
Organism Homo sapiens (human)
Definition Homo sapiens small nuclear ribonucleoprotein polypeptide N (SNRPN), transcript variant 3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_022806

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
ATGACTGTTG GCAAGAGTAG CAAGATGCTG CAGCACATTG ACTATAGAAT GAGATGTATC 
CTGCAAGATG GCCGAATCTT CATTGGCACC TTTAAGGCTT TTGACAAGCA TATGAATTTG
ATCCTCTGTG ATTGTGATGA GTTCAGAAAG ATCAAGCCAA AGAATGCGAA GCAACCAGAG
CGTGAAGAAA AGCGGGTTTT GGGTCTGGTG TTGCTGCGTG GGGAGAACTT GGTATCCATG
ACTGTGGAGG GGCCACCCCC CAAAGATACT GGCATTGCTC GGGTACCACT TGCTGGAGCT
GCTGGAGGCC CTGGGGTTGG TAGGGCAGCT GGTAGAGGAG TACCAGCTGG TGTGCCAATT
CCCCAGGCCC CTGCTGGATT GGCAGGCCCT GTCCGAGGAG TTGGGGGACC ATCCCAGCAG
GTAATGACTC CACAGGGAAG AGGCACTGTA GCAGCTGCTG CTGTTGCTGC GACTGCCAGT
ATTGCTGGAG CCCCAACACA GTACCCACCA GGACGGGGCA CTCCGCCCCC ACCCGTCGGC
AGAGCAACCC CACCTCCAGG CATTATGGCT CCTCCACCTG GTATGAGACC ACCCATGGGC
CCACCAATTG GGCTTCCCCC TGCTCGAGGG ACGCCAATAG GCATGCCGCC TCCGGGAATG
AGACCCCCTC CACCAGGCAT TAGAGGTCCA CCTCCCCCAG GAATGCGTCC ACCAAGACCT
TAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu17081
Accession Version NM_022807.2 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 723bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product small nuclear ribonucleoprotein-associated protein N
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from U41303.1 and L80005.1. This sequence is a reference standard in the RefSeqGene project. On Apr 4, 2003 this sequence version replaced gi:13027647. Summary: The protein encoded by this gene is one polypeptide of a small nuclear ribonucleoprotein complex and belongs to the snRNP SMB/SMN family. The protein plays a role in pre-mRNA processing, possibly tissue-specific alternative splicing events. Although individual snRNPs are believed to recognize specific nucleic acid sequences through RNA-RNA base pairing, the specific role of this family member is unknown. The protein arises from a bicistronic transcript that also encodes a protein identified as the SNRPN upstream reading frame (SNURF). Multiple transcription initiation sites have been identified and extensive alternative splicing occurs in the 5' untranslated region. Additional splice variants have been described but sequences for the complete transcripts have not been determined. The 5' UTR of this gene has been identified as an imprinting center. Alternative splicing or deletion caused by a translocation event in this paternally-expressed region is responsible for Angelman syndrome or Prader-Willi syndrome due to parental imprint switch failure. [provided by RefSeq, Jul 2008]. Transcript Variant: This variant (4) lacks exon 1 but utilizes upstream, non-coding exons u1B' (downstream alternative splice donor site for u1B), u1B*, u2 and u4. Alternative splicing takes place only in the 5' UTR, resulting in variants that all share exons 2-10, encoding identical proteins. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##RefSeq-Attributes-START## imprinted gene :: PMID: 7512861 ##RefSeq-Attributes-END## ##Evidence-Data-START## Transcript exon combination :: L80005.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA962337, SAMEA962346 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

1
61
121
181
241
301
361
421
481
541
601
661
721
ATGACTGTTG GCAAGAGTAG CAAGATGCTG CAGCACATTG ACTATAGAAT GAGATGTATC 
CTGCAAGATG GCCGAATCTT CATTGGCACC TTTAAGGCTT TTGACAAGCA TATGAATTTG
ATCCTCTGTG ATTGTGATGA GTTCAGAAAG ATCAAGCCAA AGAATGCGAA GCAACCAGAG
CGTGAAGAAA AGCGGGTTTT GGGTCTGGTG TTGCTGCGTG GGGAGAACTT GGTATCCATG
ACTGTGGAGG GGCCACCCCC CAAAGATACT GGCATTGCTC GGGTACCACT TGCTGGAGCT
GCTGGAGGCC CTGGGGTTGG TAGGGCAGCT GGTAGAGGAG TACCAGCTGG TGTGCCAATT
CCCCAGGCCC CTGCTGGATT GGCAGGCCCT GTCCGAGGAG TTGGGGGACC ATCCCAGCAG
GTAATGACTC CACAGGGAAG AGGCACTGTA GCAGCTGCTG CTGTTGCTGC GACTGCCAGT
ATTGCTGGAG CCCCAACACA GTACCCACCA GGACGGGGCA CTCCGCCCCC ACCCGTCGGC
AGAGCAACCC CACCTCCAGG CATTATGGCT CCTCCACCTG GTATGAGACC ACCCATGGGC
CCACCAATTG GGCTTCCCCC TGCTCGAGGG ACGCCAATAG GCATGCCGCC TCCGGGAATG
AGACCCCCTC CACCAGGCAT TAGAGGTCCA CCTCCCCCAG GAATGCGTCC ACCAAGACCT
TAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeqNP_073718.1
CDS891..1613
Misc Feature(1)1..204(+)
Misc Feature(2)205..312(+)
Misc Feature(3)313..386(+)
Misc Feature(4)387..500(+)
Misc Feature(5)792..794(+)
Misc Feature(6)903..1139(+)
Misc Feature(7)912..1136(+)
Misc Feature(8)939..1019(+)
Misc Feature(9)948..1127(+)
Misc Feature(10)996..1115(+)
Misc Feature(11)1095..1130(+)
Misc Feature(12)1413..1598(+)
Exon (1)1..204
Gene:SNRPN
Gene Synonym:
Exon (2)205..312
Gene:SNRPN
Gene Synonym:
Exon (3)313..386
Gene:SNRPN
Gene Synonym:
Exon (4)387..500
Gene:SNRPN
Gene Synonym:
Exon (5)501..596
Gene:SNRPN
Gene Synonym:
Exon (6)597..747
Gene:SNRPN
Gene Synonym:
Exon (7)748..893
Gene:SNRPN
Gene Synonym:
Exon (8)894..1045
Gene:SNRPN
Gene Synonym:
Exon (9)1046..1157
Gene:SNRPN
Gene Synonym:
Exon (10)1158..1310
Gene:SNRPN
Gene Synonym:
Exon (11)1311..1449
Gene:SNRPN
Gene Synonym:
Exon (12)1450..1575
Gene:SNRPN
Gene Synonym:
Exon (13)1576..1751
Gene:SNRPN
Gene Synonym:
Translation
Position Chain Variation Link
1 1 a, c dbSNP:531983841
20 20 c, t dbSNP:746318333
29 29 c, g dbSNP:145889115
40 40 a, g dbSNP:567196678
44 44 g, t dbSNP:74005355
51 51 g, t dbSNP:145814686
74 74 a, g dbSNP:146599298
77 77 c, t dbSNP:753201810
94 94 g, t dbSNP:567787688
110 110 c, t dbSNP:538301088
156 156 a, g dbSNP:181347216
207 207 a, g dbSNP:190646376
219 219 c, t dbSNP:7170796
280 280 a, g dbSNP:550305467
291 291 c, t dbSNP:571569609
307 307 a, g dbSNP:58890023
322 322 c, t dbSNP:80135925
337 337 a, c dbSNP:531664883
370 370 a, c, g dbSNP:550112116
386 386 c, g dbSNP:565041964
418 418 c, t dbSNP:571418891
426 426 a, t dbSNP:115572613
467 467 c, t dbSNP:547200109
495 495 c, t dbSNP:565390737
503 503 a, g dbSNP:770705956
505 505 c, t dbSNP:776280755
513 513 c, t dbSNP:426541
521 521 a, g dbSNP:371527962
527 527 a, c dbSNP:779706602
531 531 a, g dbSNP:775190608
533 533 a, g dbSNP:762505215
537 537 c, t dbSNP:768170160
538 538 a, g dbSNP:199839388
555 555 a, c dbSNP:760960743
556 556 a, c dbSNP:11555312
559 559 g, t dbSNP:766822978
565 565 c, t dbSNP:754147955
566 566 a, g dbSNP:755265989
578 578 c, t dbSNP:779082047
590 590 a, g dbSNP:752792774
594 594 a, g dbSNP:376718476
595 595 a, g dbSNP:145306813
606 606 c, g dbSNP:755907959
609 609 c, t dbSNP:779865576
610 610 a, c dbSNP:758784397
611 611 c, t dbSNP:372295822
615 615 c, g dbSNP:148434270
616 616 c, t dbSNP:375510236
617 617 a, g, t dbSNP:142583293
618 618 c, t dbSNP:150955815
629 629 a, c, g dbSNP:765651266
632 632 a, g dbSNP:775831235
638 638 a, c dbSNP:763207021
640 640 a, g dbSNP:764282322
646 646 a, g dbSNP:751683227
649 649 c, t dbSNP:757200665
659 659 a, g dbSNP:781290013
660 660 a, g dbSNP:201516822
668 668 a, g dbSNP:767497295
671 671 c, t dbSNP:750271724
672 672 a, g, t dbSNP:200974605
684 684 c, g dbSNP:780059834
704 704 a, g dbSNP:749060545
706 706 c, t dbSNP:556831171
707 707 a, g dbSNP:778377202
709 709 a, g dbSNP:747719993
710 710 c, t dbSNP:115773942
714 714 a, g dbSNP:777204652
719 719 c, t dbSNP:372124469
721 721 a, g dbSNP:770257423
726 726 c, t dbSNP:369310410
730 730 a, g dbSNP:763259089
732 732 c, t dbSNP:768955159
735 735 a, t dbSNP:372969461
738 738 c, g dbSNP:774369656
750 750 c, t dbSNP:146374207
752 752 a, c dbSNP:3210366
755 755 c, g dbSNP:3210367
760 760 a, c dbSNP:11555010
781 781 g, t dbSNP:190439178
800 800 c, t dbSNP:557418874
802 802 c, t dbSNP:705
803 803 a, g dbSNP:201873312
810 810 a, c dbSNP:770742454
815 815 -, tatc dbSNP:772922093
851 851 a, c, g dbSNP:767553112
852 852 a, g dbSNP:75184959
859 859 c, g dbSNP:766395506
867 867 a, g dbSNP:199694871
871 871 g, t dbSNP:763736287
881 881 a, c, t dbSNP:368498622
890 890 c, t dbSNP:758068137
891 891 a, g dbSNP:777191177
897 897 a, g dbSNP:751103846
928 928 c, t dbSNP:756691188
935 935 -, t dbSNP:770445659
963 963 a, c dbSNP:780552612
964 964 a, g dbSNP:749853771
965 965 a, g dbSNP:567291118
972 972 a, t dbSNP:779184888
974 974 c, t dbSNP:748523454
992 992 g, t dbSNP:772205730
1007 1007 g, t dbSNP:377759095
1016 1016 c, t dbSNP:745944032
1043 1043 a, c dbSNP:747086080
1045 1045 a, g dbSNP:771074349
1057 1057 c, t dbSNP:571239725
1058 1058 a, g dbSNP:762669644
1064 1064 a, g dbSNP:763936171
1071 1071 c, g dbSNP:774128917
1072 1072 a, g dbSNP:761495657
1073 1073 c, t dbSNP:373215950
1104 1104 c, t dbSNP:749922581
1108 1108 a, g dbSNP:755610165
1139 1139 c, g dbSNP:765663018
1145 1145 a, g dbSNP:753186914
1147 1147 c, t dbSNP:758956901
1148 1148 c, t dbSNP:778345787
1151 1151 a, c, g, t dbSNP:200650114
1157 1157 c, t dbSNP:200092176
1167 1167 g, t dbSNP:200334709
1175 1175 a, g dbSNP:747941335
1178 1178 a, g dbSNP:771792556
1190 1190 c, t dbSNP:772865283
1226 1226 a, g dbSNP:760439672
1230 1230 g, t dbSNP:370688371
1237 1237 c, t dbSNP:200977523
1238 1238 c, t dbSNP:759079550
1250 1250 -, c dbSNP:34310223
1252 1252 c, t dbSNP:565012889
1253 1253 a, c dbSNP:142287541
1255 1255 a, c dbSNP:762396703
1259 1259 c, t dbSNP:767992679
1298 1298 a, t dbSNP:368006860
1311 1311 a, g dbSNP:777534123
1317 1317 a, t dbSNP:376675210
1334 1334 c, t dbSNP:746827268
1335 1335 a, g dbSNP:756947921
1337 1337 c, t dbSNP:781125322
1344 1344 -, gct dbSNP:761391559
1352 1352 a, t dbSNP:368621460
1357 1357 c, t dbSNP:372352489
1360 1360 c, t dbSNP:775190561
1364 1364 c, t dbSNP:1048231
1368 1368 a, g dbSNP:748700221
1380 1380 g, t dbSNP:772663663
1386 1386 a, g dbSNP:773523359
1390 1390 a, g dbSNP:761114054
1395 1395 c, t dbSNP:377153548
1412 1412 a, t dbSNP:776971923
1415 1415 a, g dbSNP:369947986
1421 1421 a, t dbSNP:765419900
1422 1422 c, g dbSNP:752794820
1424 1424 c, g, t dbSNP:35757423
1427 1427 c, t dbSNP:764108793
1428 1428 a, g dbSNP:374810704
1437 1437 a, g dbSNP:369210394
1439 1439 c, g dbSNP:781177011
1444 1444 c, t dbSNP:750225490
1446 1446 c, t dbSNP:71461576
1463 1463 c, t dbSNP:775919725
1466 1466 a, c dbSNP:763124504
1467 1467 c, g dbSNP:768904469
1468 1468 c, t dbSNP:774320395
1478 1478 a, g dbSNP:761947143
1484 1484 c, t dbSNP:767568767
1492 1492 c, t dbSNP:773223686
1496 1496 a, c dbSNP:760673179
1502 1502 g, t dbSNP:766149753
1514 1514 c, g, t dbSNP:200487846
1522 1522 c, t dbSNP:764893207
1523 1523 a, g dbSNP:372752818
1527 1527 a, g dbSNP:762574002
1537 1537 c, t dbSNP:777253872
1538 1538 a, g dbSNP:746441330
1547 1547 a, g dbSNP:375488054
1554 1554 c, t dbSNP:780336659
1571 1571 g, t dbSNP:749619229
1581 1581 c, t dbSNP:199833583
1598 1598 a, t dbSNP:755315127
1626 1626 c, g, t dbSNP:376058438
1628 1628 a, c dbSNP:772389635
1632 1632 c, g dbSNP:773471460
1633 1633 a, t dbSNP:747036997
1636 1636 c, t dbSNP:770805478
1637 1637 a, t dbSNP:369397502
1638 1638 c, g, t dbSNP:112904440
1640 1640 g, t dbSNP:759379892
1646 1646 c, t dbSNP:374839284
1652 1652 a, g dbSNP:554720050
1654 1654 a, g dbSNP:775235918
1655 1655 c, t dbSNP:762643841
1656 1656 a, g dbSNP:189125295
1662 1662 c, t dbSNP:751103806
1678 1678 a, g dbSNP:537311445
1741 1741 a, g dbSNP:143504129
1747 1747 c, t dbSNP:2732052

Target ORF information:

RefSeq Version NM_022807
Organism Homo sapiens (human)
Definition Homo sapiens small nuclear ribonucleoprotein polypeptide N (SNRPN), transcript variant 4, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_022807

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
ATGACTGTTG GCAAGAGTAG CAAGATGCTG CAGCACATTG ACTATAGAAT GAGATGTATC 
CTGCAAGATG GCCGAATCTT CATTGGCACC TTTAAGGCTT TTGACAAGCA TATGAATTTG
ATCCTCTGTG ATTGTGATGA GTTCAGAAAG ATCAAGCCAA AGAATGCGAA GCAACCAGAG
CGTGAAGAAA AGCGGGTTTT GGGTCTGGTG TTGCTGCGTG GGGAGAACTT GGTATCCATG
ACTGTGGAGG GGCCACCCCC CAAAGATACT GGCATTGCTC GGGTACCACT TGCTGGAGCT
GCTGGAGGCC CTGGGGTTGG TAGGGCAGCT GGTAGAGGAG TACCAGCTGG TGTGCCAATT
CCCCAGGCCC CTGCTGGATT GGCAGGCCCT GTCCGAGGAG TTGGGGGACC ATCCCAGCAG
GTAATGACTC CACAGGGAAG AGGCACTGTA GCAGCTGCTG CTGTTGCTGC GACTGCCAGT
ATTGCTGGAG CCCCAACACA GTACCCACCA GGACGGGGCA CTCCGCCCCC ACCCGTCGGC
AGAGCAACCC CACCTCCAGG CATTATGGCT CCTCCACCTG GTATGAGACC ACCCATGGGC
CCACCAATTG GGCTTCCCCC TGCTCGAGGG ACGCCAATAG GCATGCCGCC TCCGGGAATG
AGACCCCCTC CACCAGGCAT TAGAGGTCCA CCTCCCCCAG GAATGCGTCC ACCAAGACCT
TAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu17081
Accession Version NM_022808.2 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 723bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product small nuclear ribonucleoprotein-associated protein N
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from U41303.1 and L80005.1. On Apr 4, 2003 this sequence version replaced gi:13027649. Summary: The protein encoded by this gene is one polypeptide of a small nuclear ribonucleoprotein complex and belongs to the snRNP SMB/SMN family. The protein plays a role in pre-mRNA processing, possibly tissue-specific alternative splicing events. Although individual snRNPs are believed to recognize specific nucleic acid sequences through RNA-RNA base pairing, the specific role of this family member is unknown. The protein arises from a bicistronic transcript that also encodes a protein identified as the SNRPN upstream reading frame (SNURF). Multiple transcription initiation sites have been identified and extensive alternative splicing occurs in the 5' untranslated region. Additional splice variants have been described but sequences for the complete transcripts have not been determined. The 5' UTR of this gene has been identified as an imprinting center. Alternative splicing or deletion caused by a translocation event in this paternally-expressed region is responsible for Angelman syndrome or Prader-Willi syndrome due to parental imprint switch failure. [provided by RefSeq, Jul 2008]. Transcript Variant: This variant (5) lacks exon 1 but utilizes upstream, non-coding exons u1B' (downstream alternative splice donor site for u1B), u2 and u4. Alternative splicing takes place only in the 5' UTR, resulting in variants that all share exons 2-10, encoding identical proteins. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##RefSeq-Attributes-START## imprinted gene :: PMID: 7512861 ##RefSeq-Attributes-END## ##Evidence-Data-START## CDS exon combination :: L80004.1, BC000611.2 [ECO:0000331] RNAseq introns :: single sample supports all introns SAMEA2154665 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

1
61
121
181
241
301
361
421
481
541
601
661
721
ATGACTGTTG GCAAGAGTAG CAAGATGCTG CAGCACATTG ACTATAGAAT GAGATGTATC 
CTGCAAGATG GCCGAATCTT CATTGGCACC TTTAAGGCTT TTGACAAGCA TATGAATTTG
ATCCTCTGTG ATTGTGATGA GTTCAGAAAG ATCAAGCCAA AGAATGCGAA GCAACCAGAG
CGTGAAGAAA AGCGGGTTTT GGGTCTGGTG TTGCTGCGTG GGGAGAACTT GGTATCCATG
ACTGTGGAGG GGCCACCCCC CAAAGATACT GGCATTGCTC GGGTACCACT TGCTGGAGCT
GCTGGAGGCC CTGGGGTTGG TAGGGCAGCT GGTAGAGGAG TACCAGCTGG TGTGCCAATT
CCCCAGGCCC CTGCTGGATT GGCAGGCCCT GTCCGAGGAG TTGGGGGACC ATCCCAGCAG
GTAATGACTC CACAGGGAAG AGGCACTGTA GCAGCTGCTG CTGTTGCTGC GACTGCCAGT
ATTGCTGGAG CCCCAACACA GTACCCACCA GGACGGGGCA CTCCGCCCCC ACCCGTCGGC
AGAGCAACCC CACCTCCAGG CATTATGGCT CCTCCACCTG GTATGAGACC ACCCATGGGC
CCACCAATTG GGCTTCCCCC TGCTCGAGGG ACGCCAATAG GCATGCCGCC TCCGGGAATG
AGACCCCCTC CACCAGGCAT TAGAGGTCCA CCTCCCCCAG GAATGCGTCC ACCAAGACCT
TAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeqNP_073719.1
CDS783..1505
Misc Feature(1)1..204(+)
Misc Feature(2)205..278(+)
Misc Feature(3)279..392(+)
Misc Feature(4)684..686(+)
Misc Feature(5)795..1031(+)
Misc Feature(6)804..1028(+)
Misc Feature(7)831..911(+)
Misc Feature(8)840..1019(+)
Misc Feature(9)888..1007(+)
Misc Feature(10)987..1022(+)
Misc Feature(11)1305..1490(+)
Exon (1)1..204
Gene:SNRPN
Gene Synonym:
Exon (2)205..278
Gene:SNRPN
Gene Synonym:
Exon (3)279..392
Gene:SNRPN
Gene Synonym:
Exon (4)393..488
Gene:SNRPN
Gene Synonym:
Exon (5)489..639
Gene:SNRPN
Gene Synonym:
Exon (6)640..785
Gene:SNRPN
Gene Synonym:
Exon (7)786..937
Gene:SNRPN
Gene Synonym:
Exon (8)938..1049
Gene:SNRPN
Gene Synonym:
Exon (9)1050..1202
Gene:SNRPN
Gene Synonym:
Exon (10)1203..1341
Gene:SNRPN
Gene Synonym:
Exon (11)1342..1467
Gene:SNRPN
Gene Synonym:
Exon (12)1468..1643
Gene:SNRPN
Gene Synonym:
Translation
Position Chain Variation Link
1 1 a, c dbSNP:531983841
20 20 c, t dbSNP:746318333
29 29 c, g dbSNP:145889115
40 40 a, g dbSNP:567196678
44 44 g, t dbSNP:74005355
51 51 g, t dbSNP:145814686
74 74 a, g dbSNP:146599298
77 77 c, t dbSNP:753201810
94 94 g, t dbSNP:567787688
110 110 c, t dbSNP:538301088
156 156 a, g dbSNP:181347216
214 214 c, t dbSNP:80135925
229 229 a, c dbSNP:531664883
262 262 a, c, g dbSNP:550112116
278 278 c, g dbSNP:565041964
310 310 c, t dbSNP:571418891
318 318 a, t dbSNP:115572613
359 359 c, t dbSNP:547200109
387 387 c, t dbSNP:565390737
395 395 a, g dbSNP:770705956
397 397 c, t dbSNP:776280755
405 405 c, t dbSNP:426541
413 413 a, g dbSNP:371527962
419 419 a, c dbSNP:779706602
423 423 a, g dbSNP:775190608
425 425 a, g dbSNP:762505215
429 429 c, t dbSNP:768170160
430 430 a, g dbSNP:199839388
447 447 a, c dbSNP:760960743
448 448 a, c dbSNP:11555312
451 451 g, t dbSNP:766822978
457 457 c, t dbSNP:754147955
458 458 a, g dbSNP:755265989
470 470 c, t dbSNP:779082047
482 482 a, g dbSNP:752792774
486 486 a, g dbSNP:376718476
487 487 a, g dbSNP:145306813
498 498 c, g dbSNP:755907959
501 501 c, t dbSNP:779865576
502 502 a, c dbSNP:758784397
503 503 c, t dbSNP:372295822
507 507 c, g dbSNP:148434270
508 508 c, t dbSNP:375510236
509 509 a, g, t dbSNP:142583293
510 510 c, t dbSNP:150955815
521 521 a, c, g dbSNP:765651266
524 524 a, g dbSNP:775831235
530 530 a, c dbSNP:763207021
532 532 a, g dbSNP:764282322
538 538 a, g dbSNP:751683227
541 541 c, t dbSNP:757200665
551 551 a, g dbSNP:781290013
552 552 a, g dbSNP:201516822
560 560 a, g dbSNP:767497295
563 563 c, t dbSNP:750271724
564 564 a, g, t dbSNP:200974605
576 576 c, g dbSNP:780059834
596 596 a, g dbSNP:749060545
598 598 c, t dbSNP:556831171
599 599 a, g dbSNP:778377202
601 601 a, g dbSNP:747719993
602 602 c, t dbSNP:115773942
606 606 a, g dbSNP:777204652
611 611 c, t dbSNP:372124469
613 613 a, g dbSNP:770257423
618 618 c, t dbSNP:369310410
622 622 a, g dbSNP:763259089
624 624 c, t dbSNP:768955159
627 627 a, t dbSNP:372969461
630 630 c, g dbSNP:774369656
642 642 c, t dbSNP:146374207
644 644 a, c dbSNP:3210366
647 647 c, g dbSNP:3210367
652 652 a, c dbSNP:11555010
673 673 g, t dbSNP:190439178
692 692 c, t dbSNP:557418874
694 694 c, t dbSNP:705
695 695 a, g dbSNP:201873312
702 702 a, c dbSNP:770742454
707 707 -, tatc dbSNP:772922093
743 743 a, c, g dbSNP:767553112
744 744 a, g dbSNP:75184959
751 751 c, g dbSNP:766395506
759 759 a, g dbSNP:199694871
763 763 g, t dbSNP:763736287
773 773 a, c, t dbSNP:368498622
782 782 c, t dbSNP:758068137
783 783 a, g dbSNP:777191177
789 789 a, g dbSNP:751103846
820 820 c, t dbSNP:756691188
827 827 -, t dbSNP:770445659
855 855 a, c dbSNP:780552612
856 856 a, g dbSNP:749853771
857 857 a, g dbSNP:567291118
864 864 a, t dbSNP:779184888
866 866 c, t dbSNP:748523454
884 884 g, t dbSNP:772205730
899 899 g, t dbSNP:377759095
908 908 c, t dbSNP:745944032
935 935 a, c dbSNP:747086080
937 937 a, g dbSNP:771074349
949 949 c, t dbSNP:571239725
950 950 a, g dbSNP:762669644
956 956 a, g dbSNP:763936171
963 963 c, g dbSNP:774128917
964 964 a, g dbSNP:761495657
965 965 c, t dbSNP:373215950
996 996 c, t dbSNP:749922581
1000 1000 a, g dbSNP:755610165
1031 1031 c, g dbSNP:765663018
1037 1037 a, g dbSNP:753186914
1039 1039 c, t dbSNP:758956901
1040 1040 c, t dbSNP:778345787
1043 1043 a, c, g, t dbSNP:200650114
1049 1049 c, t dbSNP:200092176
1059 1059 g, t dbSNP:200334709
1067 1067 a, g dbSNP:747941335
1070 1070 a, g dbSNP:771792556
1082 1082 c, t dbSNP:772865283
1118 1118 a, g dbSNP:760439672
1122 1122 g, t dbSNP:370688371
1129 1129 c, t dbSNP:200977523
1130 1130 c, t dbSNP:759079550
1142 1142 -, c dbSNP:34310223
1144 1144 c, t dbSNP:565012889
1145 1145 a, c dbSNP:142287541
1147 1147 a, c dbSNP:762396703
1151 1151 c, t dbSNP:767992679
1190 1190 a, t dbSNP:368006860
1203 1203 a, g dbSNP:777534123
1209 1209 a, t dbSNP:376675210
1226 1226 c, t dbSNP:746827268
1227 1227 a, g dbSNP:756947921
1229 1229 c, t dbSNP:781125322
1236 1236 -, gct dbSNP:761391559
1244 1244 a, t dbSNP:368621460
1249 1249 c, t dbSNP:372352489
1252 1252 c, t dbSNP:775190561
1256 1256 c, t dbSNP:1048231
1260 1260 a, g dbSNP:748700221
1272 1272 g, t dbSNP:772663663
1278 1278 a, g dbSNP:773523359
1282 1282 a, g dbSNP:761114054
1287 1287 c, t dbSNP:377153548
1304 1304 a, t dbSNP:776971923
1307 1307 a, g dbSNP:369947986
1313 1313 a, t dbSNP:765419900
1314 1314 c, g dbSNP:752794820
1316 1316 c, g, t dbSNP:35757423
1319 1319 c, t dbSNP:764108793
1320 1320 a, g dbSNP:374810704
1329 1329 a, g dbSNP:369210394
1331 1331 c, g dbSNP:781177011
1336 1336 c, t dbSNP:750225490
1338 1338 c, t dbSNP:71461576
1355 1355 c, t dbSNP:775919725
1358 1358 a, c dbSNP:763124504
1359 1359 c, g dbSNP:768904469
1360 1360 c, t dbSNP:774320395
1370 1370 a, g dbSNP:761947143
1376 1376 c, t dbSNP:767568767
1384 1384 c, t dbSNP:773223686
1388 1388 a, c dbSNP:760673179
1394 1394 g, t dbSNP:766149753
1406 1406 c, g, t dbSNP:200487846
1414 1414 c, t dbSNP:764893207
1415 1415 a, g dbSNP:372752818
1419 1419 a, g dbSNP:762574002
1429 1429 c, t dbSNP:777253872
1430 1430 a, g dbSNP:746441330
1439 1439 a, g dbSNP:375488054
1446 1446 c, t dbSNP:780336659
1463 1463 g, t dbSNP:749619229
1473 1473 c, t dbSNP:199833583
1490 1490 a, t dbSNP:755315127
1518 1518 c, g, t dbSNP:376058438
1520 1520 a, c dbSNP:772389635
1524 1524 c, g dbSNP:773471460
1525 1525 a, t dbSNP:747036997
1528 1528 c, t dbSNP:770805478
1529 1529 a, t dbSNP:369397502
1530 1530 c, g, t dbSNP:112904440
1532 1532 g, t dbSNP:759379892
1538 1538 c, t dbSNP:374839284
1544 1544 a, g dbSNP:554720050
1546 1546 a, g dbSNP:775235918
1547 1547 c, t dbSNP:762643841
1548 1548 a, g dbSNP:189125295
1554 1554 c, t dbSNP:751103806
1570 1570 a, g dbSNP:537311445
1633 1633 a, g dbSNP:143504129
1639 1639 c, t dbSNP:2732052

Target ORF information:

RefSeq Version NM_022808
Organism Homo sapiens (human)
Definition Homo sapiens small nuclear ribonucleoprotein polypeptide N (SNRPN), transcript variant 5, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_022808

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
ATGACTGTTG GCAAGAGTAG CAAGATGCTG CAGCACATTG ACTATAGAAT GAGATGTATC 
CTGCAAGATG GCCGAATCTT CATTGGCACC TTTAAGGCTT TTGACAAGCA TATGAATTTG
ATCCTCTGTG ATTGTGATGA GTTCAGAAAG ATCAAGCCAA AGAATGCGAA GCAACCAGAG
CGTGAAGAAA AGCGGGTTTT GGGTCTGGTG TTGCTGCGTG GGGAGAACTT GGTATCCATG
ACTGTGGAGG GGCCACCCCC CAAAGATACT GGCATTGCTC GGGTACCACT TGCTGGAGCT
GCTGGAGGCC CTGGGGTTGG TAGGGCAGCT GGTAGAGGAG TACCAGCTGG TGTGCCAATT
CCCCAGGCCC CTGCTGGATT GGCAGGCCCT GTCCGAGGAG TTGGGGGACC ATCCCAGCAG
GTAATGACTC CACAGGGAAG AGGCACTGTA GCAGCTGCTG CTGTTGCTGC GACTGCCAGT
ATTGCTGGAG CCCCAACACA GTACCCACCA GGACGGGGCA CTCCGCCCCC ACCCGTCGGC
AGAGCAACCC CACCTCCAGG CATTATGGCT CCTCCACCTG GTATGAGACC ACCCATGGGC
CCACCAATTG GGCTTCCCCC TGCTCGAGGG ACGCCAATAG GCATGCCGCC TCCGGGAATG
AGACCCCCTC CACCAGGCAT TAGAGGTCCA CCTCCCCCAG GAATGCGTCC ACCAAGACCT
TAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

 
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