The following SPINK1 gene sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SPINK1 gene which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
||ORF Nucleotide Sequence (Length: 240bp)
||pcDNA3.1+/C-(K)DYK or customized vector
|Tag on pcDNA3.1+/C-(K)DYK
||C terminal DYKDDDDK tags
|ORF Insert Method
||CloneEZ® Seamless cloning technology
||Homo sapiens (human)
||pancreatic secretory trypsin inhibitor precursor
||REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from CB159576.1, BC025790.1 and
This sequence is a reference standard in the RefSeqGene project.
On or before Jun 20, 2014 this sequence version replaced
Summary: The protein encoded by this gene is a trypsin inhibitor,
which is secreted from pancreatic acinar cells into pancreatic
juice. It is thought to function in the prevention of
trypsin-catalyzed premature activation of zymogens within the
pancreas and the pancreatic duct. Mutations in this gene are
associated with hereditary pancreatitis and tropical calcific
pancreatitis. [provided by RefSeq, Oct 2008].
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
Transcript exon combination :: CB159576.1 [ECO:0000332]
RNAseq introns :: single sample supports all introns
COMPLETENESS: complete on the 3' end.