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STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) [Homo sapiens (human)]

Gene Symbol STAT3
Entrez Gene ID 6774
Full Name signal transducer and activator of transcription 3 (acute-phase response factor)
Synonyms ADMIO, APRF, HIES
General protein information
Preferred Names
signal transducer and activator of transcription 3
Names
signal transducer and activator of transcription 3
DNA-binding protein APRF
acute-phase response factor
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

17

17q21.31

Summary The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. This protein mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis. The small GTPase Rac1 has been shown to bind and regulate the activity of this protein. PIAS3 protein is a specific inhibitor of this protein. Three alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]. lac of sum
Disorder MIM:

102582

Disorder Html: Hyper-IgE recurrent infection syndrome, 147060 (3)





The following STAT3 gene sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the STAT3 gene which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu26660 XM_011525145 PREDICTED: Homo sapiens signal transducer and activator of transcription 3 (acute-phase response factor) (STAT3), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$559
OHu26660 XM_005257617 PREDICTED: Homo sapiens signal transducer and activator of transcription 3 (acute-phase response factor) (STAT3), transcript variant X2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$559
OHu26778 XM_005257616 PREDICTED: Homo sapiens signal transducer and activator of transcription 3 (acute-phase response factor) (STAT3), transcript variant X3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$559
OHu26606 XM_011525146 PREDICTED: Homo sapiens signal transducer and activator of transcription 3 (acute-phase response factor) (STAT3), transcript variant X4, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 12-14 Quote Price
OHu26660 NM_139276 Homo sapiens signal transducer and activator of transcription 3 (acute-phase response factor) (STAT3), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$559
OHu26778 NM_003150 Homo sapiens signal transducer and activator of transcription 3 (acute-phase response factor) (STAT3), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$779
OHu26606 NM_213662 Homo sapiens signal transducer and activator of transcription 3 (acute-phase response factor) (STAT3), transcript variant 3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 12-14 Quote Price

*Business Day
**You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.


CloneID OHu26660
Accession Version XM_011525145.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 2313bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector Document: User manual_GenEZ ORF Clone Products.pdf (pdf)
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags Document: MSDS_GenEZ ORF Clone Products.pdf (pdf)
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear Document: OHu26660D_COA.pdf (pdf)
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product signal transducer and activator of transcription 3 isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_010783.16) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
ATGGCCCAAT GGAATCAGCT ACAGCAGCTT GACACACGGT ACCTGGAGCA GCTCCATCAG 
CTCTACAGTG ACAGCTTCCC AATGGAGCTG CGGCAGTTTC TGGCCCCTTG GATTGAGAGT
CAAGATTGGG CATATGCGGC CAGCAAAGAA TCACATGCCA CTTTGGTGTT TCATAATCTC
CTGGGAGAGA TTGACCAGCA GTATAGCCGC TTCCTGCAAG AGTCGAATGT TCTCTATCAG
CACAATCTAC GAAGAATCAA GCAGTTTCTT CAGAGCAGGT ATCTTGAGAA GCCAATGGAG
ATTGCCCGGA TTGTGGCCCG GTGCCTGTGG GAAGAATCAC GCCTTCTACA GACTGCAGCC
ACTGCGGCCC AGCAAGGGGG CCAGGCCAAC CACCCCACAG CAGCCGTGGT GACGGAGAAG
CAGCAGATGC TGGAGCAGCA CCTTCAGGAT GTCCGGAAGA GAGTGCAGGA TCTAGAACAG
AAAATGAAAG TGGTAGAGAA TCTCCAGGAT GACTTTGATT TCAACTATAA AACCCTCAAG
AGTCAAGGAG ACATGCAAGA TCTGAATGGA AACAACCAGT CAGTGACCAG GCAGAAGATG
CAGCAGCTGG AACAGATGCT CACTGCGCTG GACCAGATGC GGAGAAGCAT CGTGAGTGAG
CTGGCGGGGC TTTTGTCAGC GATGGAGTAC GTGCAGAAAA CTCTCACGGA CGAGGAGCTG
GCTGACTGGA AGAGGCGGCA ACAGATTGCC TGCATTGGAG GCCCGCCCAA CATCTGCCTA
GATCGGCTAG AAAACTGGAT AACGTCATTA GCAGAATCTC AACTTCAGAC CCGTCAACAA
ATTAAGAAAC TGGAGGAGTT GCAGCAAAAA GTTTCCTACA AAGGGGACCC CATTGTACAG
CACCGGCCGA TGCTGGAGGA GAGAATCGTG GAGCTGTTTA GAAACTTAAT GAAAAGTGCC
TTTGTGGTGG AGCGGCAGCC CTGCATGCCC ATGCATCCTG ACCGGCCCCT CGTCATCAAG
ACCGGCGTCC AGTTCACTAC TAAAGTCAGG TTGCTGGTCA AATTCCCTGA GTTGAATTAT
CAGCTTAAAA TTAAAGTGTG CATTGACAAA GACTCTGGGG ACGTTGCAGC TCTCAGAGGA
TCCCGGAAAT TTAACATTCT GGGCACAAAC ACAAAAGTGA TGAACATGGA AGAATCCAAC
AACGGCAGCC TCTCTGCAGA ATTCAAACAC TTGACCCTGA GGGAGCAGAG ATGTGGGAAT
GGGGGCCGAG CCAATTGTGA TGCTTCCCTG ATTGTGACTG AGGAGCTGCA CCTGATCACC
TTTGAGACCG AGGTGTATCA CCAAGGCCTC AAGATTGACC TAGAGACCCA CTCCTTGCCA
GTTGTGGTGA TCTCCAACAT CTGTCAGATG CCAAATGCCT GGGCGTCCAT CCTGTGGTAC
AACATGCTGA CCAACAATCC CAAGAATGTA AACTTTTTTA CCAAGCCCCC AATTGGAACC
TGGGATCAAG TGGCCGAGGT CCTGAGCTGG CAGTTCTCCT CCACCACCAA GCGAGGACTG
AGCATCGAGC AGCTGACTAC ACTGGCAGAG AAACTCTTGG GACCTGGTGT GAATTATTCA
GGGTGTCAGA TCACATGGGC TAAATTTTGC AAAGAAAACA TGGCTGGCAA GGGCTTCTCC
TTCTGGGTCT GGCTGGACAA TATCATTGAC CTTGTGAAAA AGTACATCCT GGCCCTTTGG
AACGAAGGGT ACATCATGGG CTTTATCAGT AAGGAGCGGG AGCGGGCCAT CTTGAGCACT
AAGCCTCCAG GCACCTTCCT GCTAAGATTC AGTGAAAGCA GCAAAGAAGG AGGCGTCACT
TTCACTTGGG TGGAGAAGGA CATCAGCGGT AAGACCCAGA TCCAGTCCGT GGAACCATAC
ACAAAGCAGC AGCTGAACAA CATGTCATTT GCTGAAATCA TCATGGGCTA TAAGATCATG
GATGCTACCA ATATCCTGGT GTCTCCACTG GTCTATCTCT ATCCTGACAT TCCCAAGGAG
GAGGCATTCG GAAAGTATTG TCGGCCAGAG AGCCAGGAGC ATCCTGAAGC TGACCCAGGT
AGCGCTGCCC CATACCTGAA GACCAAGTTT ATCTGTGTGA CACCAACGAC CTGCAGCAAT
ACCATTGACC TGCCGATGTC CCCCCGCACT TTAGATTCAT TGATGCAGTT TGGAAATAAT
GGTGAAGGTG CTGAACCCTC AGCAGGAGGG CAGTTTGAGT CCCTCACCTT TGACATGGAG
TTGACCTCGG AGTGCGCTAC CTCCCCCATG TGA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqXP_011523447.1
CDS229..2541
Misc Feature(1)232..588(+)
Misc Feature(2)643..1185(+)
Misc Feature(3)1189..1950(+)
Misc Feature(4)1888..2373(+)
Misc Feature(5)1999..2142(+)
Misc Feature(6)2137..2187(+)
Misc Feature(7)2167..2358(+)
Translation
Position Chain Variation Link
13 13 c, g dbSNP:765882801
41 41 c, g dbSNP:566151688
44 44 c, g dbSNP:547925260
53 53 c, g dbSNP:780393027
83 83 c, t dbSNP:760179821
108 108 c, t dbSNP:528219097
109 109 a, g dbSNP:17883843
226 226 a, g dbSNP:779793392
228 228 c, g dbSNP:756099567
237 237 a, g dbSNP:749859511
266 266 a, g dbSNP:780720013
276 276 a, g dbSNP:563996007
291 291 c, g dbSNP:541045758
298 298 a, g dbSNP:751281347
300 300 c, t dbSNP:763742034
322 322 a, c dbSNP:1803125
327 327 c, t dbSNP:758631901
331 331 g, t dbSNP:748204289
363 363 a, c, t dbSNP:766994331
366 366 a, g dbSNP:760775429
371 371 a, g, t dbSNP:766875947
375 375 a, g dbSNP:767594035
387 387 c, t dbSNP:762135443
422 422 a, g dbSNP:775122881
424 424 c, g dbSNP:375760579
441 441 c, t dbSNP:530451908
453 453 a, g dbSNP:146184566
473 473 a, g dbSNP:776494537
475 475 c, t dbSNP:770878694
481 481 a, c dbSNP:746486285
531 531 c, t dbSNP:747612981
537 537 a, c, g dbSNP:17880940
548 548 a, g dbSNP:749626783
551 551 a, g dbSNP:780604324
555 555 g, t dbSNP:759676110
561 561 a, g dbSNP:750994809
564 564 a, g dbSNP:200440712
576 576 a, g dbSNP:200960081
580 580 a, t dbSNP:757305223
589 589 a, t dbSNP:751614036
591 591 a, t dbSNP:764338385
593 593 c, t dbSNP:774724351
601 601 c, g dbSNP:574370336
603 603 a, g dbSNP:747081170
605 605 a, g dbSNP:777883261
609 609 c, t dbSNP:758609919
633 633 c, t dbSNP:201846078
642 642 a, g dbSNP:765452694
648 648 a, g dbSNP:755877110
654 654 a, g dbSNP:774823374
657 657 a, g dbSNP:17878478
658 658 c, t dbSNP:761693018
663 663 a, g dbSNP:773889504
676 676 -, g dbSNP:35332755
741 741 c, t dbSNP:777828006
751 751 a, c dbSNP:758408552
763 763 c, t dbSNP:748237742
765 765 c, t dbSNP:779055365
779 779 a, g dbSNP:748184550
780 780 c, t dbSNP:202126764
786 786 a, g dbSNP:768898076
790 790 a, c dbSNP:749529243
795 795 a, t dbSNP:781034418
798 798 a, t dbSNP:756935531
815 815 a, c dbSNP:751411956
822 822 c, g dbSNP:374063766
849 849 c, t dbSNP:758449863
852 852 c, t dbSNP:752235250
855 855 a, c, g dbSNP:759225787
871 871 a, g dbSNP:753370239
879 879 c, t dbSNP:377095381
884 884 a, g dbSNP:762301765
888 888 a, g dbSNP:774652472
893 893 c, t dbSNP:764674735
894 894 a, g dbSNP:762891098
909 909 a, g dbSNP:775680553
915 915 a, g dbSNP:769885072
918 918 c, t dbSNP:746151758
921 921 g, t dbSNP:374524373
934 934 a, t dbSNP:773138024
935 935 c, g dbSNP:371541785
937 937 a, g dbSNP:376677265
939 939 c, t dbSNP:17882069
946 946 c, t dbSNP:754971639
951 951 a, c, t dbSNP:139588729
954 954 a, c dbSNP:755746762
967 967 c, t dbSNP:750141391
971 971 a, c dbSNP:757347742
974 974 c, t dbSNP:767159289
993 993 a, g dbSNP:527634708
1006 1006 c, g, t dbSNP:764478072
1018 1018 a, g dbSNP:763564047
1023 1023 a, c dbSNP:775421377
1027 1027 a, g dbSNP:749302989
1031 1031 a, c dbSNP:779422770
1032 1032 a, g dbSNP:755554248
1045 1045 c, t dbSNP:745393806
1050 1050 a, g dbSNP:780773507
1053 1053 g, t dbSNP:200098006
1062 1062 c, t dbSNP:751849047
1092 1092 c, g dbSNP:1064110
1107 1107 c, t dbSNP:147186377
1137 1137 a, g dbSNP:764577805
1141 1141 c, t dbSNP:758828674
1152 1152 a, g dbSNP:1064111
1155 1155 c, t dbSNP:779733888
1156 1156 a, g dbSNP:765856200
1167 1167 c, t dbSNP:1141111
1207 1207 c, g dbSNP:759527569
1231 1231 c, t dbSNP:193922716
1232 1232 a, g dbSNP:776115471
1239 1239 c, t dbSNP:200623682
1240 1240 a, g dbSNP:371953916
1251 1251 c, t dbSNP:777436789
1254 1254 c, t dbSNP:539947939
1267 1267 a, g dbSNP:748496600
1273 1273 a, g dbSNP:368454926
1275 1275 c, t dbSNP:779464807
1277 1277 g, t dbSNP:755524497
1278 1278 a, g dbSNP:771738153
1281 1281 a, g dbSNP:201472943
1287 1287 c, t dbSNP:774847480
1290 1290 a, g dbSNP:1141112
1301 1301 g, t dbSNP:769072802
1344 1344 c, t dbSNP:770311773
1350 1350 c, t dbSNP:376080249
1351 1351 a, g dbSNP:781724933
1355 1355 c, t dbSNP:373083464
1371 1371 c, g dbSNP:143571879
1372 1372 c, t dbSNP:113994135
1373 1373 a, g, t dbSNP:113994136
1394 1394 c, t dbSNP:397514766
1397 1397 a, g dbSNP:566350932
1403 1403 a, g dbSNP:587777648
1428 1428 c, t dbSNP:757298594
1431 1431 c, t dbSNP:189708970
1432 1432 a, g dbSNP:763754846
1443 1443 c, t dbSNP:769971732
1458 1458 c, t dbSNP:138001349
1465 1465 c, t dbSNP:146946014
1471 1471 a, g dbSNP:193922717
1473 1473 a, g dbSNP:184867029
1491 1491 a, g dbSNP:141151719
1496 1496 a, g dbSNP:113994137
1499 1499 c, t dbSNP:768739455
1508 1508 a, g dbSNP:749583802
1512 1512 c, t dbSNP:775806195
1548 1548 c, g dbSNP:770170991
1557 1557 a, c, t dbSNP:147955721
1559 1559 a, c dbSNP:771888821
1560 1560 a, g dbSNP:748180243
1572 1572 a, g dbSNP:778716670
1575 1575 c, t dbSNP:1141115
1579 1579 a, c dbSNP:768150168
1589 1589 c, t dbSNP:748564923
1591 1591 g, t dbSNP:34460718
1596 1596 a, c, t dbSNP:769425072
1606 1606 c, t dbSNP:1141116
1609 1609 c, g dbSNP:149214040
1615 1615 -, gtg dbSNP:113994138
1653 1653 a, g dbSNP:780713214
1656 1656 c, t dbSNP:369714894
1683 1683 a, c dbSNP:751900728
1687 1687 c, t dbSNP:199996352
1698 1698 a, g dbSNP:1141117
1704 1704 c, t dbSNP:1141118
1707 1707 c, t dbSNP:1141119
1710 1710 c, t dbSNP:1141120
1716 1716 c, g, t dbSNP:1141121
1720 1720 a, g dbSNP:146620441
1734 1734 c, t dbSNP:1064112
1737 1737 a, c dbSNP:763944667
1743 1743 c, t dbSNP:762743967
1747 1747 g, t dbSNP:145786768
1749 1749 c, g dbSNP:1064113
1752 1752 c, g dbSNP:1064114
1767 1767 c, g dbSNP:1064115
1781 1781 a, g dbSNP:765182656
1795 1795 a, g dbSNP:759053963
1798 1798 a, c dbSNP:776053336
1806 1806 a, c, t dbSNP:1141122
1809 1809 a, g dbSNP:1141123
1815 1815 a, t dbSNP:1141125
1821 1821 a, g dbSNP:1141126
1825 1825 c, t dbSNP:199855499
1831 1831 c, t dbSNP:769706649
1835 1835 g, t dbSNP:372641163
1842 1842 c, t dbSNP:1141127
1845 1845 c, t dbSNP:1141128
1853 1853 a, g dbSNP:781353111
1872 1872 a, c dbSNP:1141129
1875 1875 c, t dbSNP:1141131
1878 1878 c, t dbSNP:201555354
1892 1892 c, t dbSNP:754677708
1905 1905 c, t dbSNP:753693925
1908 1908 c, t dbSNP:146817483
1910 1910 a, t dbSNP:1064116
1915 1915 a, g, t dbSNP:749943696
1923 1923 a, g dbSNP:1064117
1935 1935 c, t dbSNP:1064118
1950 1950 a, g dbSNP:767204952
1953 1953 c, t dbSNP:1064119
1955 1955 c, t dbSNP:751201012
1971 1971 c, t dbSNP:1141144
1982 1982 c, t dbSNP:756779964
1998 1998 c, t dbSNP:1141145
2000 2000 a, t dbSNP:193922719
2004 2004 a, g dbSNP:370905622
2008 2008 a, g dbSNP:193922720
2011 2011 c, t dbSNP:149791519
2014 2014 a, g dbSNP:758127158
2018 2018 -, a dbSNP:33997807
2022 2022 a, g dbSNP:376413845
2026 2026 a, g dbSNP:765516506
2030 2030 a, g dbSNP:759905653
2034 2034 c, t dbSNP:777070160
2037 2037 a, g dbSNP:766899484
2052 2052 a, g dbSNP:1064120
2053 2053 a, c dbSNP:1064121
2055 2055 a, c dbSNP:1064122
2082 2082 c, t dbSNP:117691970
2083 2083 a, g dbSNP:773386939
2085 2085 a, c dbSNP:772174970
2094 2094 c, t dbSNP:748472407
2096 2096 g, t dbSNP:786205503
2106 2106 a, g dbSNP:774445141
2115 2115 c, t dbSNP:769658142
2137 2137 a, g dbSNP:113994139
2147 2147 a, t dbSNP:769031989
2148 2148 c, t dbSNP:751536580
2166 2166 c, g dbSNP:587777649
2168 2168 a, g, t dbSNP:770986654
2190 2190 c, t dbSNP:746896356
2196 2196 c, t dbSNP:777585143
2198 2198 a, g dbSNP:193922721
2202 2202 c, g dbSNP:587777650
2205 2205 c, t dbSNP:771560652
2209 2209 g, t dbSNP:747639500
2232 2232 c, t dbSNP:778501578
2250 2250 c, t dbSNP:754672701
2277 2277 c, t dbSNP:373256669
2278 2278 a, c, g dbSNP:780466766
2288 2288 a, g dbSNP:756441740
2310 2310 a, t dbSNP:139701269
2319 2319 a, t dbSNP:200529713
2332 2332 a, g dbSNP:747667389
2333 2333 c, g dbSNP:778450270
2362 2362 c, t dbSNP:193922722
2367 2367 a, g dbSNP:768290157
2378 2378 c, t dbSNP:587777647
2388 2388 a, g, t dbSNP:761802498
2390 2390 c, g dbSNP:774279920
2391 2391 a, c dbSNP:768099770
2396 2396 a, c dbSNP:748822559
2397 2397 c, g dbSNP:775171412
2402 2402 c, t dbSNP:769372865
2408 2408 c, t dbSNP:11547455
2428 2428 c, t dbSNP:746221967
2430 2430 a, g dbSNP:781470131
2446 2446 a, c dbSNP:757779747
2448 2448 c, t dbSNP:747460012
2451 2451 c, t dbSNP:778445506
2456 2456 g, t dbSNP:151033214
2466 2466 c, t dbSNP:376372615
2496 2496 c, t dbSNP:752248821
2509 2509 c, t dbSNP:142236792
2513 2513 c, t dbSNP:759106857
2516 2516 c, t dbSNP:140604473
2517 2517 a, g dbSNP:147202525
2520 2520 a, g dbSNP:368404940
2522 2522 a, g dbSNP:773766015
2523 2523 c, g, t dbSNP:145244024
2524 2524 a, g dbSNP:779485558
2527 2527 a, g dbSNP:183996904
2532 2532 c, t dbSNP:568695064
2544 2544 a, c dbSNP:749420271
2550 2550 a, g dbSNP:780221973
2553 2553 c, t dbSNP:374327257
2554 2554 a, g dbSNP:756380897
2567 2567 a, g dbSNP:368050581
2568 2568 -, g dbSNP:748972949
2572 2572 c, g, t dbSNP:374107124
2573 2573 a, g dbSNP:752520342
2576 2576 g, t dbSNP:7207492
2581 2581 c, t dbSNP:758935946
2582 2582 a, g dbSNP:557841793
2588 2588 c, t dbSNP:375752935
2597 2597 c, g dbSNP:368388401
2604 2604 c, t dbSNP:769563218
2664 2664 -, t dbSNP:201259337
2664 2664 a, t dbSNP:745710035
2695 2695 c, t dbSNP:1803126
2732 2732 a, c, g dbSNP:571072469
2752 2752 a, c dbSNP:41289087
2758 2758 a, g dbSNP:374525108
2773 2773 c, g dbSNP:530910704
2782 2782 a, g dbSNP:570130402
2789 2789 a, g dbSNP:548332594
2800 2800 a, g, t dbSNP:530088285
2802 2802 a, g dbSNP:561673659
2805 2805 -, g dbSNP:554015274
2837 2837 a, g dbSNP:746452227
2845 2845 a, g dbSNP:566824382
2860 2860 c, t dbSNP:117735406
2892 2892 -, gtt dbSNP:533596827
2909 2909 c, t dbSNP:113644902
2943 2943 a, g dbSNP:186798539
2948 2948 c, t dbSNP:777345728
2975 2975 -, a dbSNP:767787925
2976 2976 c, t dbSNP:540114461
3001 3001 c, t dbSNP:528332516
3051 3051 c, t dbSNP:563944808
3068 3068 c, t dbSNP:572165563
3076 3076 a, g dbSNP:569395714
3078 3078 a, g dbSNP:545977519
3082 3082 -, a dbSNP:368910594
3090 3090 c, t dbSNP:539172696
3123 3123 a, t dbSNP:115090026
3125 3125 g, t dbSNP:11079042
3150 3150 c, t dbSNP:759943258
3160 3160 a, c dbSNP:751996505
3210 3210 c, t dbSNP:138998960
3230 3230 a, c dbSNP:766973491
3271 3271 a, g dbSNP:555637030
3306 3306 a, g dbSNP:535612802
3323 3323 a, g dbSNP:552970845
3326 3326 g, t dbSNP:535347870
3339 3339 c, t dbSNP:577565516
3394 3394 a, g dbSNP:559241286
3404 3404 -, ga dbSNP:763595711
3434 3434 -, a dbSNP:754306251
3435 3435 -, g dbSNP:373212106
3436 3436 a, g dbSNP:537640981
3466 3466 -, t dbSNP:752673079
3484 3484 c, t dbSNP:367884098
3572 3572 a, g dbSNP:146907042
3616 3616 a, g dbSNP:536318793
3623 3623 g, t dbSNP:184030721
3655 3655 c, t dbSNP:569957236
3666 3666 a, g dbSNP:377364072
3706 3706 -, c dbSNP:35427318
3737 3737 c, t dbSNP:193126798
3770 3770 a, g dbSNP:112608032
3800 3800 c, t dbSNP:372716251
3801 3801 c, t dbSNP:149628743
3835 3835 g, t dbSNP:556139569
3849 3849 a, g dbSNP:756528147
3857 3857 a, g dbSNP:552123985
3866 3866 a, g dbSNP:3744483
3874 3874 c, t dbSNP:75018295
3890 3890 a, g dbSNP:541925122
3892 3892 a, c dbSNP:188588928
3923 3923 -, ag dbSNP:781243612
3924 3924 c, g dbSNP:183293865
3959 3959 c, t dbSNP:547767441
3962 3962 c, t dbSNP:541024608
3963 3963 a, g dbSNP:577652056
3966 3966 a, g dbSNP:559186748
3997 3997 c, t dbSNP:537273486
4004 4004 c, t dbSNP:576595680
4033 4033 a, g dbSNP:554827097
4038 4038 a, g dbSNP:190710939
4058 4058 a, g dbSNP:75454844
4078 4078 a, c dbSNP:185508151
4140 4140 a, c dbSNP:763077835
4145 4145 g, t dbSNP:111904020
4148 4148 g, t dbSNP:547430088
4169 4169 c, g dbSNP:182824638
4212 4212 c, t dbSNP:1053004
4234 4234 a, g dbSNP:373503231
4279 4279 c, g dbSNP:552467234
4282 4282 a, g dbSNP:530683057
4290 4290 c, t dbSNP:769760865
4375 4375 g, t dbSNP:10775
4382 4382 c, t dbSNP:376764794
4394 4394 a, g dbSNP:1053005
4409 4409 a, g dbSNP:548033008
4472 4472 a, g dbSNP:138326799
4542 4542 g, t dbSNP:150467429
4543 4543 a, g dbSNP:531760487
4551 4551 c, t dbSNP:541059766
4555 4555 a, g dbSNP:532120833
4612 4612 c, g dbSNP:564695836
4688 4688 a, g dbSNP:1053023
4758 4758 a, g dbSNP:576615644
4799 4799 -, t dbSNP:751300490
4862 4862 a, g dbSNP:762995262
4872 4872 a, g dbSNP:555195129
4884 4884 -, gtc dbSNP:773939681
4884 4884 c, t dbSNP:200029754
4885 4885 -, t dbSNP:398041696
4886 4886 c, t dbSNP:80323123
4905 4905 -, tt dbSNP:760910438
4906 4906 -, t dbSNP:397857989
4907 4907 g, t dbSNP:147045863

Target ORF information:

RefSeq Version XM_011525145
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens signal transducer and activator of transcription 3 (acute-phase response factor) (STAT3), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011525145

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
ATGGCCCAAT GGAATCAGCT ACAGCAGCTT GACACACGGT ACCTGGAGCA GCTCCATCAG 
CTCTACAGTG ACAGCTTCCC AATGGAGCTG CGGCAGTTTC TGGCCCCTTG GATTGAGAGT
CAAGATTGGG CATATGCGGC CAGCAAAGAA TCACATGCCA CTTTGGTGTT TCATAATCTC
CTGGGAGAGA TTGACCAGCA GTATAGCCGC TTCCTGCAAG AGTCGAATGT TCTCTATCAG
CACAATCTAC GAAGAATCAA GCAGTTTCTT CAGAGCAGGT ATCTTGAGAA GCCAATGGAG
ATTGCCCGGA TTGTGGCCCG GTGCCTGTGG GAAGAATCAC GCCTTCTACA GACTGCAGCC
ACTGCGGCCC AGCAAGGGGG CCAGGCCAAC CACCCCACAG CAGCCGTGGT GACGGAGAAG
CAGCAGATGC TGGAGCAGCA CCTTCAGGAT GTCCGGAAGA GAGTGCAGGA TCTAGAACAG
AAAATGAAAG TGGTAGAGAA TCTCCAGGAT GACTTTGATT TCAACTATAA AACCCTCAAG
AGTCAAGGAG ACATGCAAGA TCTGAATGGA AACAACCAGT CAGTGACCAG GCAGAAGATG
CAGCAGCTGG AACAGATGCT CACTGCGCTG GACCAGATGC GGAGAAGCAT CGTGAGTGAG
CTGGCGGGGC TTTTGTCAGC GATGGAGTAC GTGCAGAAAA CTCTCACGGA CGAGGAGCTG
GCTGACTGGA AGAGGCGGCA ACAGATTGCC TGCATTGGAG GCCCGCCCAA CATCTGCCTA
GATCGGCTAG AAAACTGGAT AACGTCATTA GCAGAATCTC AACTTCAGAC CCGTCAACAA
ATTAAGAAAC TGGAGGAGTT GCAGCAAAAA GTTTCCTACA AAGGGGACCC CATTGTACAG
CACCGGCCGA TGCTGGAGGA GAGAATCGTG GAGCTGTTTA GAAACTTAAT GAAAAGTGCC
TTTGTGGTGG AGCGGCAGCC CTGCATGCCC ATGCATCCTG ACCGGCCCCT CGTCATCAAG
ACCGGCGTCC AGTTCACTAC TAAAGTCAGG TTGCTGGTCA AATTCCCTGA GTTGAATTAT
CAGCTTAAAA TTAAAGTGTG CATTGACAAA GACTCTGGGG ACGTTGCAGC TCTCAGAGGA
TCCCGGAAAT TTAACATTCT GGGCACAAAC ACAAAAGTGA TGAACATGGA AGAATCCAAC
AACGGCAGCC TCTCTGCAGA ATTCAAACAC TTGACCCTGA GGGAGCAGAG ATGTGGGAAT
GGGGGCCGAG CCAATTGTGA TGCTTCCCTG ATTGTGACTG AGGAGCTGCA CCTGATCACC
TTTGAGACCG AGGTGTATCA CCAAGGCCTC AAGATTGACC TAGAGACCCA CTCCTTGCCA
GTTGTGGTGA TCTCCAACAT CTGTCAGATG CCAAATGCCT GGGCGTCCAT CCTGTGGTAC
AACATGCTGA CCAACAATCC CAAGAATGTA AACTTTTTTA CCAAGCCCCC AATTGGAACC
TGGGATCAAG TGGCCGAGGT CCTGAGCTGG CAGTTCTCCT CCACCACCAA GCGAGGACTG
AGCATCGAGC AGCTGACTAC ACTGGCAGAG AAACTCTTGG GACCTGGTGT GAATTATTCA
GGGTGTCAGA TCACATGGGC TAAATTTTGC AAAGAAAACA TGGCTGGCAA GGGCTTCTCC
TTCTGGGTCT GGCTGGACAA TATCATTGAC CTTGTGAAAA AGTACATCCT GGCCCTTTGG
AACGAAGGGT ACATCATGGG CTTTATCAGT AAGGAGCGGG AGCGGGCCAT CTTGAGCACT
AAGCCTCCAG GCACCTTCCT GCTAAGATTC AGTGAAAGCA GCAAAGAAGG AGGCGTCACT
TTCACTTGGG TGGAGAAGGA CATCAGCGGT AAGACCCAGA TCCAGTCCGT GGAACCATAC
ACAAAGCAGC AGCTGAACAA CATGTCATTT GCTGAAATCA TCATGGGCTA TAAGATCATG
GATGCTACCA ATATCCTGGT GTCTCCACTG GTCTATCTCT ATCCTGACAT TCCCAAGGAG
GAGGCATTCG GAAAGTATTG TCGGCCAGAG AGCCAGGAGC ATCCTGAAGC TGACCCAGGT
AGCGCTGCCC CATACCTGAA GACCAAGTTT ATCTGTGTGA CACCAACGAC CTGCAGCAAT
ACCATTGACC TGCCGATGTC CCCCCGCACT TTAGATTCAT TGATGCAGTT TGGAAATAAT
GGTGAAGGTG CTGAACCCTC AGCAGGAGGG CAGTTTGAGT CCCTCACCTT TGACATGGAG
TTGACCTCGG AGTGCGCTAC CTCCCCCATG TGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu26660
Accession Version XM_005257617.2 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 2313bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector Document: User manual_GenEZ ORF Clone Products.pdf (pdf)
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags Document: MSDS_GenEZ ORF Clone Products.pdf (pdf)
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear Document: OHu26660D_COA.pdf (pdf)
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product signal transducer and activator of transcription 3 isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_010783.16) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 12, 2015 this sequence version replaced gi:530412748. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
ATGGCCCAAT GGAATCAGCT ACAGCAGCTT GACACACGGT ACCTGGAGCA GCTCCATCAG 
CTCTACAGTG ACAGCTTCCC AATGGAGCTG CGGCAGTTTC TGGCCCCTTG GATTGAGAGT
CAAGATTGGG CATATGCGGC CAGCAAAGAA TCACATGCCA CTTTGGTGTT TCATAATCTC
CTGGGAGAGA TTGACCAGCA GTATAGCCGC TTCCTGCAAG AGTCGAATGT TCTCTATCAG
CACAATCTAC GAAGAATCAA GCAGTTTCTT CAGAGCAGGT ATCTTGAGAA GCCAATGGAG
ATTGCCCGGA TTGTGGCCCG GTGCCTGTGG GAAGAATCAC GCCTTCTACA GACTGCAGCC
ACTGCGGCCC AGCAAGGGGG CCAGGCCAAC CACCCCACAG CAGCCGTGGT GACGGAGAAG
CAGCAGATGC TGGAGCAGCA CCTTCAGGAT GTCCGGAAGA GAGTGCAGGA TCTAGAACAG
AAAATGAAAG TGGTAGAGAA TCTCCAGGAT GACTTTGATT TCAACTATAA AACCCTCAAG
AGTCAAGGAG ACATGCAAGA TCTGAATGGA AACAACCAGT CAGTGACCAG GCAGAAGATG
CAGCAGCTGG AACAGATGCT CACTGCGCTG GACCAGATGC GGAGAAGCAT CGTGAGTGAG
CTGGCGGGGC TTTTGTCAGC GATGGAGTAC GTGCAGAAAA CTCTCACGGA CGAGGAGCTG
GCTGACTGGA AGAGGCGGCA ACAGATTGCC TGCATTGGAG GCCCGCCCAA CATCTGCCTA
GATCGGCTAG AAAACTGGAT AACGTCATTA GCAGAATCTC AACTTCAGAC CCGTCAACAA
ATTAAGAAAC TGGAGGAGTT GCAGCAAAAA GTTTCCTACA AAGGGGACCC CATTGTACAG
CACCGGCCGA TGCTGGAGGA GAGAATCGTG GAGCTGTTTA GAAACTTAAT GAAAAGTGCC
TTTGTGGTGG AGCGGCAGCC CTGCATGCCC ATGCATCCTG ACCGGCCCCT CGTCATCAAG
ACCGGCGTCC AGTTCACTAC TAAAGTCAGG TTGCTGGTCA AATTCCCTGA GTTGAATTAT
CAGCTTAAAA TTAAAGTGTG CATTGACAAA GACTCTGGGG ACGTTGCAGC TCTCAGAGGA
TCCCGGAAAT TTAACATTCT GGGCACAAAC ACAAAAGTGA TGAACATGGA AGAATCCAAC
AACGGCAGCC TCTCTGCAGA ATTCAAACAC TTGACCCTGA GGGAGCAGAG ATGTGGGAAT
GGGGGCCGAG CCAATTGTGA TGCTTCCCTG ATTGTGACTG AGGAGCTGCA CCTGATCACC
TTTGAGACCG AGGTGTATCA CCAAGGCCTC AAGATTGACC TAGAGACCCA CTCCTTGCCA
GTTGTGGTGA TCTCCAACAT CTGTCAGATG CCAAATGCCT GGGCGTCCAT CCTGTGGTAC
AACATGCTGA CCAACAATCC CAAGAATGTA AACTTTTTTA CCAAGCCCCC AATTGGAACC
TGGGATCAAG TGGCCGAGGT CCTGAGCTGG CAGTTCTCCT CCACCACCAA GCGAGGACTG
AGCATCGAGC AGCTGACTAC ACTGGCAGAG AAACTCTTGG GACCTGGTGT GAATTATTCA
GGGTGTCAGA TCACATGGGC TAAATTTTGC AAAGAAAACA TGGCTGGCAA GGGCTTCTCC
TTCTGGGTCT GGCTGGACAA TATCATTGAC CTTGTGAAAA AGTACATCCT GGCCCTTTGG
AACGAAGGGT ACATCATGGG CTTTATCAGT AAGGAGCGGG AGCGGGCCAT CTTGAGCACT
AAGCCTCCAG GCACCTTCCT GCTAAGATTC AGTGAAAGCA GCAAAGAAGG AGGCGTCACT
TTCACTTGGG TGGAGAAGGA CATCAGCGGT AAGACCCAGA TCCAGTCCGT GGAACCATAC
ACAAAGCAGC AGCTGAACAA CATGTCATTT GCTGAAATCA TCATGGGCTA TAAGATCATG
GATGCTACCA ATATCCTGGT GTCTCCACTG GTCTATCTCT ATCCTGACAT TCCCAAGGAG
GAGGCATTCG GAAAGTATTG TCGGCCAGAG AGCCAGGAGC ATCCTGAAGC TGACCCAGGT
AGCGCTGCCC CATACCTGAA GACCAAGTTT ATCTGTGTGA CACCAACGAC CTGCAGCAAT
ACCATTGACC TGCCGATGTC CCCCCGCACT TTAGATTCAT TGATGCAGTT TGGAAATAAT
GGTGAAGGTG CTGAACCCTC AGCAGGAGGG CAGTTTGAGT CCCTCACCTT TGACATGGAG
TTGACCTCGG AGTGCGCTAC CTCCCCCATG TGA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqXP_005257674.2
CDS227..2539
Misc Feature(1)230..586(+)
Misc Feature(2)641..1183(+)
Misc Feature(3)1187..1948(+)
Misc Feature(4)1886..2371(+)
Misc Feature(5)1997..2140(+)
Misc Feature(6)2135..2185(+)
Misc Feature(7)2165..2356(+)
Translation
Position Chain Variation Link
14 14 c, g dbSNP:765882801
42 42 c, g dbSNP:566151688
45 45 c, g dbSNP:547925260
54 54 c, g dbSNP:780393027
84 84 c, t dbSNP:760179821
109 109 c, t dbSNP:528219097
110 110 a, g dbSNP:17883843
226 226 c, g dbSNP:756099567
235 235 a, g dbSNP:749859511
264 264 a, g dbSNP:780720013
274 274 a, g dbSNP:563996007
289 289 c, g dbSNP:541045758
296 296 a, g dbSNP:751281347
298 298 c, t dbSNP:763742034
320 320 a, c dbSNP:1803125
325 325 c, t dbSNP:758631901
329 329 g, t dbSNP:748204289
361 361 a, c, t dbSNP:766994331
364 364 a, g dbSNP:760775429
369 369 a, g, t dbSNP:766875947
373 373 a, g dbSNP:767594035
385 385 c, t dbSNP:762135443
420 420 a, g dbSNP:775122881
422 422 c, g dbSNP:375760579
439 439 c, t dbSNP:530451908
451 451 a, g dbSNP:146184566
471 471 a, g dbSNP:776494537
473 473 c, t dbSNP:770878694
479 479 a, c dbSNP:746486285
529 529 c, t dbSNP:747612981
535 535 a, c, g dbSNP:17880940
546 546 a, g dbSNP:749626783
549 549 a, g dbSNP:780604324
553 553 g, t dbSNP:759676110
559 559 a, g dbSNP:750994809
562 562 a, g dbSNP:200440712
574 574 a, g dbSNP:200960081
578 578 a, t dbSNP:757305223
587 587 a, t dbSNP:751614036
589 589 a, t dbSNP:764338385
591 591 c, t dbSNP:774724351
599 599 c, g dbSNP:574370336
601 601 a, g dbSNP:747081170
603 603 a, g dbSNP:777883261
607 607 c, t dbSNP:758609919
631 631 c, t dbSNP:201846078
640 640 a, g dbSNP:765452694
646 646 a, g dbSNP:755877110
652 652 a, g dbSNP:774823374
655 655 a, g dbSNP:17878478
656 656 c, t dbSNP:761693018
661 661 a, g dbSNP:773889504
674 674 -, g dbSNP:35332755
739 739 c, t dbSNP:777828006
749 749 a, c dbSNP:758408552
761 761 c, t dbSNP:748237742
763 763 c, t dbSNP:779055365
777 777 a, g dbSNP:748184550
778 778 c, t dbSNP:202126764
784 784 a, g dbSNP:768898076
788 788 a, c dbSNP:749529243
793 793 a, t dbSNP:781034418
796 796 a, t dbSNP:756935531
813 813 a, c dbSNP:751411956
820 820 c, g dbSNP:374063766
847 847 c, t dbSNP:758449863
850 850 c, t dbSNP:752235250
853 853 a, c, g dbSNP:759225787
869 869 a, g dbSNP:753370239
877 877 c, t dbSNP:377095381
882 882 a, g dbSNP:762301765
886 886 a, g dbSNP:774652472
891 891 c, t dbSNP:764674735
892 892 a, g dbSNP:762891098
907 907 a, g dbSNP:775680553
913 913 a, g dbSNP:769885072
916 916 c, t dbSNP:746151758
919 919 g, t dbSNP:374524373
932 932 a, t dbSNP:773138024
933 933 c, g dbSNP:371541785
935 935 a, g dbSNP:376677265
937 937 c, t dbSNP:17882069
944 944 c, t dbSNP:754971639
949 949 a, c, t dbSNP:139588729
952 952 a, c dbSNP:755746762
965 965 c, t dbSNP:750141391
969 969 a, c dbSNP:757347742
972 972 c, t dbSNP:767159289
991 991 a, g dbSNP:527634708
1004 1004 c, g, t dbSNP:764478072
1016 1016 a, g dbSNP:763564047
1021 1021 a, c dbSNP:775421377
1025 1025 a, g dbSNP:749302989
1029 1029 a, c dbSNP:779422770
1030 1030 a, g dbSNP:755554248
1043 1043 c, t dbSNP:745393806
1048 1048 a, g dbSNP:780773507
1051 1051 g, t dbSNP:200098006
1060 1060 c, t dbSNP:751849047
1090 1090 c, g dbSNP:1064110
1105 1105 c, t dbSNP:147186377
1135 1135 a, g dbSNP:764577805
1139 1139 c, t dbSNP:758828674
1150 1150 a, g dbSNP:1064111
1153 1153 c, t dbSNP:779733888
1154 1154 a, g dbSNP:765856200
1165 1165 c, t dbSNP:1141111
1205 1205 c, g dbSNP:759527569
1229 1229 c, t dbSNP:193922716
1230 1230 a, g dbSNP:776115471
1237 1237 c, t dbSNP:200623682
1238 1238 a, g dbSNP:371953916
1249 1249 c, t dbSNP:777436789
1252 1252 c, t dbSNP:539947939
1265 1265 a, g dbSNP:748496600
1271 1271 a, g dbSNP:368454926
1273 1273 c, t dbSNP:779464807
1275 1275 g, t dbSNP:755524497
1276 1276 a, g dbSNP:771738153
1279 1279 a, g dbSNP:201472943
1285 1285 c, t dbSNP:774847480
1288 1288 a, g dbSNP:1141112
1299 1299 g, t dbSNP:769072802
1342 1342 c, t dbSNP:770311773
1348 1348 c, t dbSNP:376080249
1349 1349 a, g dbSNP:781724933
1353 1353 c, t dbSNP:373083464
1369 1369 c, g dbSNP:143571879
1370 1370 c, t dbSNP:113994135
1371 1371 a, g, t dbSNP:113994136
1392 1392 c, t dbSNP:397514766
1395 1395 a, g dbSNP:566350932
1401 1401 a, g dbSNP:587777648
1426 1426 c, t dbSNP:757298594
1429 1429 c, t dbSNP:189708970
1430 1430 a, g dbSNP:763754846
1441 1441 c, t dbSNP:769971732
1456 1456 c, t dbSNP:138001349
1463 1463 c, t dbSNP:146946014
1469 1469 a, g dbSNP:193922717
1471 1471 a, g dbSNP:184867029
1489 1489 a, g dbSNP:141151719
1494 1494 a, g dbSNP:113994137
1497 1497 c, t dbSNP:768739455
1506 1506 a, g dbSNP:749583802
1510 1510 c, t dbSNP:775806195
1546 1546 c, g dbSNP:770170991
1555 1555 a, c, t dbSNP:147955721
1557 1557 a, c dbSNP:771888821
1558 1558 a, g dbSNP:748180243
1570 1570 a, g dbSNP:778716670
1573 1573 c, t dbSNP:1141115
1577 1577 a, c dbSNP:768150168
1587 1587 c, t dbSNP:748564923
1589 1589 g, t dbSNP:34460718
1594 1594 a, c, t dbSNP:769425072
1604 1604 c, t dbSNP:1141116
1607 1607 c, g dbSNP:149214040
1613 1613 -, gtg dbSNP:113994138
1651 1651 a, g dbSNP:780713214
1654 1654 c, t dbSNP:369714894
1681 1681 a, c dbSNP:751900728
1685 1685 c, t dbSNP:199996352
1696 1696 a, g dbSNP:1141117
1702 1702 c, t dbSNP:1141118
1705 1705 c, t dbSNP:1141119
1708 1708 c, t dbSNP:1141120
1714 1714 c, g, t dbSNP:1141121
1718 1718 a, g dbSNP:146620441
1732 1732 c, t dbSNP:1064112
1735 1735 a, c dbSNP:763944667
1741 1741 c, t dbSNP:762743967
1745 1745 g, t dbSNP:145786768
1747 1747 c, g dbSNP:1064113
1750 1750 c, g dbSNP:1064114
1765 1765 c, g dbSNP:1064115
1779 1779 a, g dbSNP:765182656
1793 1793 a, g dbSNP:759053963
1796 1796 a, c dbSNP:776053336
1804 1804 a, c, t dbSNP:1141122
1807 1807 a, g dbSNP:1141123
1813 1813 a, t dbSNP:1141125
1819 1819 a, g dbSNP:1141126
1823 1823 c, t dbSNP:199855499
1829 1829 c, t dbSNP:769706649
1833 1833 g, t dbSNP:372641163
1840 1840 c, t dbSNP:1141127
1843 1843 c, t dbSNP:1141128
1851 1851 a, g dbSNP:781353111
1870 1870 a, c dbSNP:1141129
1873 1873 c, t dbSNP:1141131
1876 1876 c, t dbSNP:201555354
1890 1890 c, t dbSNP:754677708
1903 1903 c, t dbSNP:753693925
1906 1906 c, t dbSNP:146817483
1908 1908 a, t dbSNP:1064116
1913 1913 a, g, t dbSNP:749943696
1921 1921 a, g dbSNP:1064117
1933 1933 c, t dbSNP:1064118
1948 1948 a, g dbSNP:767204952
1951 1951 c, t dbSNP:1064119
1953 1953 c, t dbSNP:751201012
1969 1969 c, t dbSNP:1141144
1980 1980 c, t dbSNP:756779964
1996 1996 c, t dbSNP:1141145
1998 1998 a, t dbSNP:193922719
2002 2002 a, g dbSNP:370905622
2006 2006 a, g dbSNP:193922720
2009 2009 c, t dbSNP:149791519
2012 2012 a, g dbSNP:758127158
2016 2016 -, a dbSNP:33997807
2020 2020 a, g dbSNP:376413845
2024 2024 a, g dbSNP:765516506
2028 2028 a, g dbSNP:759905653
2032 2032 c, t dbSNP:777070160
2035 2035 a, g dbSNP:766899484
2050 2050 a, g dbSNP:1064120
2051 2051 a, c dbSNP:1064121
2053 2053 a, c dbSNP:1064122
2080 2080 c, t dbSNP:117691970
2081 2081 a, g dbSNP:773386939
2083 2083 a, c dbSNP:772174970
2092 2092 c, t dbSNP:748472407
2094 2094 g, t dbSNP:786205503
2104 2104 a, g dbSNP:774445141
2113 2113 c, t dbSNP:769658142
2135 2135 a, g dbSNP:113994139
2145 2145 a, t dbSNP:769031989
2146 2146 c, t dbSNP:751536580
2164 2164 c, g dbSNP:587777649
2166 2166 a, g, t dbSNP:770986654
2188 2188 c, t dbSNP:746896356
2194 2194 c, t dbSNP:777585143
2196 2196 a, g dbSNP:193922721
2200 2200 c, g dbSNP:587777650
2203 2203 c, t dbSNP:771560652
2207 2207 g, t dbSNP:747639500
2230 2230 c, t dbSNP:778501578
2248 2248 c, t dbSNP:754672701
2275 2275 c, t dbSNP:373256669
2276 2276 a, c, g dbSNP:780466766
2286 2286 a, g dbSNP:756441740
2308 2308 a, t dbSNP:139701269
2317 2317 a, t dbSNP:200529713
2330 2330 a, g dbSNP:747667389
2331 2331 c, g dbSNP:778450270
2360 2360 c, t dbSNP:193922722
2365 2365 a, g dbSNP:768290157
2376 2376 c, t dbSNP:587777647
2386 2386 a, g, t dbSNP:761802498
2388 2388 c, g dbSNP:774279920
2389 2389 a, c dbSNP:768099770
2394 2394 a, c dbSNP:748822559
2395 2395 c, g dbSNP:775171412
2400 2400 c, t dbSNP:769372865
2406 2406 c, t dbSNP:11547455
2426 2426 c, t dbSNP:746221967
2428 2428 a, g dbSNP:781470131
2444 2444 a, c dbSNP:757779747
2446 2446 c, t dbSNP:747460012
2449 2449 c, t dbSNP:778445506
2454 2454 g, t dbSNP:151033214
2464 2464 c, t dbSNP:376372615
2494 2494 c, t dbSNP:752248821
2507 2507 c, t dbSNP:142236792
2511 2511 c, t dbSNP:759106857
2514 2514 c, t dbSNP:140604473
2515 2515 a, g dbSNP:147202525
2518 2518 a, g dbSNP:368404940
2520 2520 a, g dbSNP:773766015
2521 2521 c, g, t dbSNP:145244024
2522 2522 a, g dbSNP:779485558
2525 2525 a, g dbSNP:183996904
2530 2530 c, t dbSNP:568695064
2542 2542 a, c dbSNP:749420271
2548 2548 a, g dbSNP:780221973
2551 2551 c, t dbSNP:374327257
2552 2552 a, g dbSNP:756380897
2565 2565 a, g dbSNP:368050581
2566 2566 -, g dbSNP:748972949
2570 2570 c, g, t dbSNP:374107124
2571 2571 a, g dbSNP:752520342
2574 2574 g, t dbSNP:7207492
2579 2579 c, t dbSNP:758935946
2580 2580 a, g dbSNP:557841793
2586 2586 c, t dbSNP:375752935
2595 2595 c, g dbSNP:368388401
2602 2602 c, t dbSNP:769563218
2662 2662 -, t dbSNP:201259337
2662 2662 a, t dbSNP:745710035
2693 2693 c, t dbSNP:1803126
2730 2730 a, c, g dbSNP:571072469
2750 2750 a, c dbSNP:41289087
2756 2756 a, g dbSNP:374525108
2771 2771 c, g dbSNP:530910704
2780 2780 a, g dbSNP:570130402
2787 2787 a, g dbSNP:548332594
2798 2798 a, g, t dbSNP:530088285
2800 2800 a, g dbSNP:561673659
2803 2803 -, g dbSNP:554015274
2835 2835 a, g dbSNP:746452227
2843 2843 a, g dbSNP:566824382
2858 2858 c, t dbSNP:117735406
2890 2890 -, gtt dbSNP:533596827
2907 2907 c, t dbSNP:113644902
2941 2941 a, g dbSNP:186798539
2946 2946 c, t dbSNP:777345728
2973 2973 -, a dbSNP:767787925
2974 2974 c, t dbSNP:540114461
2999 2999 c, t dbSNP:528332516
3049 3049 c, t dbSNP:563944808
3066 3066 c, t dbSNP:572165563
3074 3074 a, g dbSNP:569395714
3076 3076 a, g dbSNP:545977519
3080 3080 -, a dbSNP:368910594
3088 3088 c, t dbSNP:539172696
3121 3121 a, t dbSNP:115090026
3123 3123 g, t dbSNP:11079042
3148 3148 c, t dbSNP:759943258
3158 3158 a, c dbSNP:751996505
3208 3208 c, t dbSNP:138998960
3228 3228 a, c dbSNP:766973491
3269 3269 a, g dbSNP:555637030
3304 3304 a, g dbSNP:535612802
3321 3321 a, g dbSNP:552970845
3324 3324 g, t dbSNP:535347870
3337 3337 c, t dbSNP:577565516
3392 3392 a, g dbSNP:559241286
3402 3402 -, ga dbSNP:763595711
3432 3432 -, a dbSNP:754306251
3433 3433 -, g dbSNP:373212106
3434 3434 a, g dbSNP:537640981
3464 3464 -, t dbSNP:752673079
3482 3482 c, t dbSNP:367884098
3570 3570 a, g dbSNP:146907042
3614 3614 a, g dbSNP:536318793
3621 3621 g, t dbSNP:184030721
3653 3653 c, t dbSNP:569957236
3664 3664 a, g dbSNP:377364072
3704 3704 -, c dbSNP:35427318
3735 3735 c, t dbSNP:193126798
3768 3768 a, g dbSNP:112608032
3798 3798 c, t dbSNP:372716251
3799 3799 c, t dbSNP:149628743
3833 3833 g, t dbSNP:556139569
3847 3847 a, g dbSNP:756528147
3855 3855 a, g dbSNP:552123985
3864 3864 a, g dbSNP:3744483
3872 3872 c, t dbSNP:75018295
3888 3888 a, g dbSNP:541925122
3890 3890 a, c dbSNP:188588928
3921 3921 -, ag dbSNP:781243612
3922 3922 c, g dbSNP:183293865
3957 3957 c, t dbSNP:547767441
3960 3960 c, t dbSNP:541024608
3961 3961 a, g dbSNP:577652056
3964 3964 a, g dbSNP:559186748
3995 3995 c, t dbSNP:537273486
4002 4002 c, t dbSNP:576595680
4031 4031 a, g dbSNP:554827097
4036 4036 a, g dbSNP:190710939
4056 4056 a, g dbSNP:75454844
4076 4076 a, c dbSNP:185508151
4138 4138 a, c dbSNP:763077835
4143 4143 g, t dbSNP:111904020
4146 4146 g, t dbSNP:547430088
4167 4167 c, g dbSNP:182824638
4210 4210 c, t dbSNP:1053004
4232 4232 a, g dbSNP:373503231
4277 4277 c, g dbSNP:552467234
4280 4280 a, g dbSNP:530683057
4288 4288 c, t dbSNP:769760865
4373 4373 g, t dbSNP:10775
4380 4380 c, t dbSNP:376764794
4392 4392 a, g dbSNP:1053005
4407 4407 a, g dbSNP:548033008
4470 4470 a, g dbSNP:138326799
4540 4540 g, t dbSNP:150467429
4541 4541 a, g dbSNP:531760487
4549 4549 c, t dbSNP:541059766
4553 4553 a, g dbSNP:532120833
4610 4610 c, g dbSNP:564695836
4686 4686 a, g dbSNP:1053023
4756 4756 a, g dbSNP:576615644
4797 4797 -, t dbSNP:751300490
4860 4860 a, g dbSNP:762995262
4870 4870 a, g dbSNP:555195129
4882 4882 -, gtc dbSNP:773939681
4882 4882 c, t dbSNP:200029754
4883 4883 -, t dbSNP:398041696
4884 4884 c, t dbSNP:80323123
4903 4903 -, tt dbSNP:760910438
4904 4904 -, t dbSNP:397857989
4905 4905 g, t dbSNP:147045863

Target ORF information:

RefSeq Version XM_005257617
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens signal transducer and activator of transcription 3 (acute-phase response factor) (STAT3), transcript variant X2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_005257617

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
ATGGCCCAAT GGAATCAGCT ACAGCAGCTT GACACACGGT ACCTGGAGCA GCTCCATCAG 
CTCTACAGTG ACAGCTTCCC AATGGAGCTG CGGCAGTTTC TGGCCCCTTG GATTGAGAGT
CAAGATTGGG CATATGCGGC CAGCAAAGAA TCACATGCCA CTTTGGTGTT TCATAATCTC
CTGGGAGAGA TTGACCAGCA GTATAGCCGC TTCCTGCAAG AGTCGAATGT TCTCTATCAG
CACAATCTAC GAAGAATCAA GCAGTTTCTT CAGAGCAGGT ATCTTGAGAA GCCAATGGAG
ATTGCCCGGA TTGTGGCCCG GTGCCTGTGG GAAGAATCAC GCCTTCTACA GACTGCAGCC
ACTGCGGCCC AGCAAGGGGG CCAGGCCAAC CACCCCACAG CAGCCGTGGT GACGGAGAAG
CAGCAGATGC TGGAGCAGCA CCTTCAGGAT GTCCGGAAGA GAGTGCAGGA TCTAGAACAG
AAAATGAAAG TGGTAGAGAA TCTCCAGGAT GACTTTGATT TCAACTATAA AACCCTCAAG
AGTCAAGGAG ACATGCAAGA TCTGAATGGA AACAACCAGT CAGTGACCAG GCAGAAGATG
CAGCAGCTGG AACAGATGCT CACTGCGCTG GACCAGATGC GGAGAAGCAT CGTGAGTGAG
CTGGCGGGGC TTTTGTCAGC GATGGAGTAC GTGCAGAAAA CTCTCACGGA CGAGGAGCTG
GCTGACTGGA AGAGGCGGCA ACAGATTGCC TGCATTGGAG GCCCGCCCAA CATCTGCCTA
GATCGGCTAG AAAACTGGAT AACGTCATTA GCAGAATCTC AACTTCAGAC CCGTCAACAA
ATTAAGAAAC TGGAGGAGTT GCAGCAAAAA GTTTCCTACA AAGGGGACCC CATTGTACAG
CACCGGCCGA TGCTGGAGGA GAGAATCGTG GAGCTGTTTA GAAACTTAAT GAAAAGTGCC
TTTGTGGTGG AGCGGCAGCC CTGCATGCCC ATGCATCCTG ACCGGCCCCT CGTCATCAAG
ACCGGCGTCC AGTTCACTAC TAAAGTCAGG TTGCTGGTCA AATTCCCTGA GTTGAATTAT
CAGCTTAAAA TTAAAGTGTG CATTGACAAA GACTCTGGGG ACGTTGCAGC TCTCAGAGGA
TCCCGGAAAT TTAACATTCT GGGCACAAAC ACAAAAGTGA TGAACATGGA AGAATCCAAC
AACGGCAGCC TCTCTGCAGA ATTCAAACAC TTGACCCTGA GGGAGCAGAG ATGTGGGAAT
GGGGGCCGAG CCAATTGTGA TGCTTCCCTG ATTGTGACTG AGGAGCTGCA CCTGATCACC
TTTGAGACCG AGGTGTATCA CCAAGGCCTC AAGATTGACC TAGAGACCCA CTCCTTGCCA
GTTGTGGTGA TCTCCAACAT CTGTCAGATG CCAAATGCCT GGGCGTCCAT CCTGTGGTAC
AACATGCTGA CCAACAATCC CAAGAATGTA AACTTTTTTA CCAAGCCCCC AATTGGAACC
TGGGATCAAG TGGCCGAGGT CCTGAGCTGG CAGTTCTCCT CCACCACCAA GCGAGGACTG
AGCATCGAGC AGCTGACTAC ACTGGCAGAG AAACTCTTGG GACCTGGTGT GAATTATTCA
GGGTGTCAGA TCACATGGGC TAAATTTTGC AAAGAAAACA TGGCTGGCAA GGGCTTCTCC
TTCTGGGTCT GGCTGGACAA TATCATTGAC CTTGTGAAAA AGTACATCCT GGCCCTTTGG
AACGAAGGGT ACATCATGGG CTTTATCAGT AAGGAGCGGG AGCGGGCCAT CTTGAGCACT
AAGCCTCCAG GCACCTTCCT GCTAAGATTC AGTGAAAGCA GCAAAGAAGG AGGCGTCACT
TTCACTTGGG TGGAGAAGGA CATCAGCGGT AAGACCCAGA TCCAGTCCGT GGAACCATAC
ACAAAGCAGC AGCTGAACAA CATGTCATTT GCTGAAATCA TCATGGGCTA TAAGATCATG
GATGCTACCA ATATCCTGGT GTCTCCACTG GTCTATCTCT ATCCTGACAT TCCCAAGGAG
GAGGCATTCG GAAAGTATTG TCGGCCAGAG AGCCAGGAGC ATCCTGAAGC TGACCCAGGT
AGCGCTGCCC CATACCTGAA GACCAAGTTT ATCTGTGTGA CACCAACGAC CTGCAGCAAT
ACCATTGACC TGCCGATGTC CCCCCGCACT TTAGATTCAT TGATGCAGTT TGGAAATAAT
GGTGAAGGTG CTGAACCCTC AGCAGGAGGG CAGTTTGAGT CCCTCACCTT TGACATGGAG
TTGACCTCGG AGTGCGCTAC CTCCCCCATG TGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu26778
Accession Version XM_005257616.2 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 2310bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector Document: User manual_GenEZ ORF Clone Products.pdf (pdf)
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags Document: MSDS_GenEZ ORF Clone Products.pdf (pdf)
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear Document: OHu26778D_COA.pdf (pdf)
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product signal transducer and activator of transcription 3 isoform X2
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_010783.16) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 12, 2015 this sequence version replaced gi:530412746. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
ATGGCCCAAT GGAATCAGCT ACAGCAGCTT GACACACGGT ACCTGGAGCA GCTCCATCAG 
CTCTACAGTG ACAGCTTCCC AATGGAGCTG CGGCAGTTTC TGGCCCCTTG GATTGAGAGT
CAAGATTGGG CATATGCGGC CAGCAAAGAA TCACATGCCA CTTTGGTGTT TCATAATCTC
CTGGGAGAGA TTGACCAGCA GTATAGCCGC TTCCTGCAAG AGTCGAATGT TCTCTATCAG
CACAATCTAC GAAGAATCAA GCAGTTTCTT CAGAGCAGGT ATCTTGAGAA GCCAATGGAG
ATTGCCCGGA TTGTGGCCCG GTGCCTGTGG GAAGAATCAC GCCTTCTACA GACTGCAGCC
ACTGCGGCCC AGCAAGGGGG CCAGGCCAAC CACCCCACAG CAGCCGTGGT GACGGAGAAG
CAGCAGATGC TGGAGCAGCA CCTTCAGGAT GTCCGGAAGA GAGTGCAGGA TCTAGAACAG
AAAATGAAAG TGGTAGAGAA TCTCCAGGAT GACTTTGATT TCAACTATAA AACCCTCAAG
AGTCAAGGAG ACATGCAAGA TCTGAATGGA AACAACCAGT CAGTGACCAG GCAGAAGATG
CAGCAGCTGG AACAGATGCT CACTGCGCTG GACCAGATGC GGAGAAGCAT CGTGAGTGAG
CTGGCGGGGC TTTTGTCAGC GATGGAGTAC GTGCAGAAAA CTCTCACGGA CGAGGAGCTG
GCTGACTGGA AGAGGCGGCA ACAGATTGCC TGCATTGGAG GCCCGCCCAA CATCTGCCTA
GATCGGCTAG AAAACTGGAT AACGTCATTA GCAGAATCTC AACTTCAGAC CCGTCAACAA
ATTAAGAAAC TGGAGGAGTT GCAGCAAAAA GTTTCCTACA AAGGGGACCC CATTGTACAG
CACCGGCCGA TGCTGGAGGA GAGAATCGTG GAGCTGTTTA GAAACTTAAT GAAAAGTGCC
TTTGTGGTGG AGCGGCAGCC CTGCATGCCC ATGCATCCTG ACCGGCCCCT CGTCATCAAG
ACCGGCGTCC AGTTCACTAC TAAAGTCAGG TTGCTGGTCA AATTCCCTGA GTTGAATTAT
CAGCTTAAAA TTAAAGTGTG CATTGACAAA GACTCTGGGG ACGTTGCAGC TCTCAGAGGA
TCCCGGAAAT TTAACATTCT GGGCACAAAC ACAAAAGTGA TGAACATGGA AGAATCCAAC
AACGGCAGCC TCTCTGCAGA ATTCAAACAC TTGACCCTGA GGGAGCAGAG ATGTGGGAAT
GGGGGCCGAG CCAATTGTGA TGCTTCCCTG ATTGTGACTG AGGAGCTGCA CCTGATCACC
TTTGAGACCG AGGTGTATCA CCAAGGCCTC AAGATTGACC TAGAGACCCA CTCCTTGCCA
GTTGTGGTGA TCTCCAACAT CTGTCAGATG CCAAATGCCT GGGCGTCCAT CCTGTGGTAC
AACATGCTGA CCAACAATCC CAAGAATGTA AACTTTTTTA CCAAGCCCCC AATTGGAACC
TGGGATCAAG TGGCCGAGGT CCTGAGCTGG CAGTTCTCCT CCACCACCAA GCGAGGACTG
AGCATCGAGC AGCTGACTAC ACTGGCAGAG AAACTCTTGG GACCTGGTGT GAATTATTCA
GGGTGTCAGA TCACATGGGC TAAATTTTGC AAAGAAAACA TGGCTGGCAA GGGCTTCTCC
TTCTGGGTCT GGCTGGACAA TATCATTGAC CTTGTGAAAA AGTACATCCT GGCCCTTTGG
AACGAAGGGT ACATCATGGG CTTTATCAGT AAGGAGCGGG AGCGGGCCAT CTTGAGCACT
AAGCCTCCAG GCACCTTCCT GCTAAGATTC AGTGAAAGCA GCAAAGAAGG AGGCGTCACT
TTCACTTGGG TGGAGAAGGA CATCAGCGGT AAGACCCAGA TCCAGTCCGT GGAACCATAC
ACAAAGCAGC AGCTGAACAA CATGTCATTT GCTGAAATCA TCATGGGCTA TAAGATCATG
GATGCTACCA ATATCCTGGT GTCTCCACTG GTCTATCTCT ATCCTGACAT TCCCAAGGAG
GAGGCATTCG GAAAGTATTG TCGGCCAGAG AGCCAGGAGC ATCCTGAAGC TGACCCAGGC
GCTGCCCCAT ACCTGAAGAC CAAGTTTATC TGTGTGACAC CAACGACCTG CAGCAATACC
ATTGACCTGC CGATGTCCCC CCGCACTTTA GATTCATTGA TGCAGTTTGG AAATAATGGT
GAAGGTGCTG AACCCTCAGC AGGAGGGCAG TTTGAGTCCC TCACCTTTGA CATGGAGTTG
ACCTCGGAGT GCGCTACCTC CCCCATGTGA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqXP_005257673.2
CDS229..2538
Misc Feature(1)232..588(+)
Misc Feature(2)643..1185(+)
Misc Feature(3)1189..1950(+)
Misc Feature(4)1888..2370(+)
Misc Feature(5)1999..2142(+)
Misc Feature(6)2137..2187(+)
Misc Feature(7)2167..2355(+)
Translation
Position Chain Variation Link
13 13 c, g dbSNP:765882801
41 41 c, g dbSNP:566151688
44 44 c, g dbSNP:547925260
53 53 c, g dbSNP:780393027
83 83 c, t dbSNP:760179821
108 108 c, t dbSNP:528219097
109 109 a, g dbSNP:17883843
226 226 a, g dbSNP:779793392
228 228 c, g dbSNP:756099567
237 237 a, g dbSNP:749859511
266 266 a, g dbSNP:780720013
276 276 a, g dbSNP:563996007
291 291 c, g dbSNP:541045758
298 298 a, g dbSNP:751281347
300 300 c, t dbSNP:763742034
322 322 a, c dbSNP:1803125
327 327 c, t dbSNP:758631901
331 331 g, t dbSNP:748204289
363 363 a, c, t dbSNP:766994331
366 366 a, g dbSNP:760775429
371 371 a, g, t dbSNP:766875947
375 375 a, g dbSNP:767594035
387 387 c, t dbSNP:762135443
422 422 a, g dbSNP:775122881
424 424 c, g dbSNP:375760579
441 441 c, t dbSNP:530451908
453 453 a, g dbSNP:146184566
473 473 a, g dbSNP:776494537
475 475 c, t dbSNP:770878694
481 481 a, c dbSNP:746486285
531 531 c, t dbSNP:747612981
537 537 a, c, g dbSNP:17880940
548 548 a, g dbSNP:749626783
551 551 a, g dbSNP:780604324
555 555 g, t dbSNP:759676110
561 561 a, g dbSNP:750994809
564 564 a, g dbSNP:200440712
576 576 a, g dbSNP:200960081
580 580 a, t dbSNP:757305223
589 589 a, t dbSNP:751614036
591 591 a, t dbSNP:764338385
593 593 c, t dbSNP:774724351
601 601 c, g dbSNP:574370336
603 603 a, g dbSNP:747081170
605 605 a, g dbSNP:777883261
609 609 c, t dbSNP:758609919
633 633 c, t dbSNP:201846078
642 642 a, g dbSNP:765452694
648 648 a, g dbSNP:755877110
654 654 a, g dbSNP:774823374
657 657 a, g dbSNP:17878478
658 658 c, t dbSNP:761693018
663 663 a, g dbSNP:773889504
676 676 -, g dbSNP:35332755
741 741 c, t dbSNP:777828006
751 751 a, c dbSNP:758408552
763 763 c, t dbSNP:748237742
765 765 c, t dbSNP:779055365
779 779 a, g dbSNP:748184550
780 780 c, t dbSNP:202126764
786 786 a, g dbSNP:768898076
790 790 a, c dbSNP:749529243
795 795 a, t dbSNP:781034418
798 798 a, t dbSNP:756935531
815 815 a, c dbSNP:751411956
822 822 c, g dbSNP:374063766
849 849 c, t dbSNP:758449863
852 852 c, t dbSNP:752235250
855 855 a, c, g dbSNP:759225787
871 871 a, g dbSNP:753370239
879 879 c, t dbSNP:377095381
884 884 a, g dbSNP:762301765
888 888 a, g dbSNP:774652472
893 893 c, t dbSNP:764674735
894 894 a, g dbSNP:762891098
909 909 a, g dbSNP:775680553
915 915 a, g dbSNP:769885072
918 918 c, t dbSNP:746151758
921 921 g, t dbSNP:374524373
934 934 a, t dbSNP:773138024
935 935 c, g dbSNP:371541785
937 937 a, g dbSNP:376677265
939 939 c, t dbSNP:17882069
946 946 c, t dbSNP:754971639
951 951 a, c, t dbSNP:139588729
954 954 a, c dbSNP:755746762
967 967 c, t dbSNP:750141391
971 971 a, c dbSNP:757347742
974 974 c, t dbSNP:767159289
993 993 a, g dbSNP:527634708
1006 1006 c, g, t dbSNP:764478072
1018 1018 a, g dbSNP:763564047
1023 1023 a, c dbSNP:775421377
1027 1027 a, g dbSNP:749302989
1031 1031 a, c dbSNP:779422770
1032 1032 a, g dbSNP:755554248
1045 1045 c, t dbSNP:745393806
1050 1050 a, g dbSNP:780773507
1053 1053 g, t dbSNP:200098006
1062 1062 c, t dbSNP:751849047
1092 1092 c, g dbSNP:1064110
1107 1107 c, t dbSNP:147186377
1137 1137 a, g dbSNP:764577805
1141 1141 c, t dbSNP:758828674
1152 1152 a, g dbSNP:1064111
1155 1155 c, t dbSNP:779733888
1156 1156 a, g dbSNP:765856200
1167 1167 c, t dbSNP:1141111
1207 1207 c, g dbSNP:759527569
1231 1231 c, t dbSNP:193922716
1232 1232 a, g dbSNP:776115471
1239 1239 c, t dbSNP:200623682
1240 1240 a, g dbSNP:371953916
1251 1251 c, t dbSNP:777436789
1254 1254 c, t dbSNP:539947939
1267 1267 a, g dbSNP:748496600
1273 1273 a, g dbSNP:368454926
1275 1275 c, t dbSNP:779464807
1277 1277 g, t dbSNP:755524497
1278 1278 a, g dbSNP:771738153
1281 1281 a, g dbSNP:201472943
1287 1287 c, t dbSNP:774847480
1290 1290 a, g dbSNP:1141112
1301 1301 g, t dbSNP:769072802
1344 1344 c, t dbSNP:770311773
1350 1350 c, t dbSNP:376080249
1351 1351 a, g dbSNP:781724933
1355 1355 c, t dbSNP:373083464
1371 1371 c, g dbSNP:143571879
1372 1372 c, t dbSNP:113994135
1373 1373 a, g, t dbSNP:113994136
1394 1394 c, t dbSNP:397514766
1397 1397 a, g dbSNP:566350932
1403 1403 a, g dbSNP:587777648
1428 1428 c, t dbSNP:757298594
1431 1431 c, t dbSNP:189708970
1432 1432 a, g dbSNP:763754846
1443 1443 c, t dbSNP:769971732
1458 1458 c, t dbSNP:138001349
1465 1465 c, t dbSNP:146946014
1471 1471 a, g dbSNP:193922717
1473 1473 a, g dbSNP:184867029
1491 1491 a, g dbSNP:141151719
1496 1496 a, g dbSNP:113994137
1499 1499 c, t dbSNP:768739455
1508 1508 a, g dbSNP:749583802
1512 1512 c, t dbSNP:775806195
1548 1548 c, g dbSNP:770170991
1557 1557 a, c, t dbSNP:147955721
1559 1559 a, c dbSNP:771888821
1560 1560 a, g dbSNP:748180243
1572 1572 a, g dbSNP:778716670
1575 1575 c, t dbSNP:1141115
1579 1579 a, c dbSNP:768150168
1589 1589 c, t dbSNP:748564923
1591 1591 g, t dbSNP:34460718
1596 1596 a, c, t dbSNP:769425072
1606 1606 c, t dbSNP:1141116
1609 1609 c, g dbSNP:149214040
1615 1615 -, gtg dbSNP:113994138
1653 1653 a, g dbSNP:780713214
1656 1656 c, t dbSNP:369714894
1683 1683 a, c dbSNP:751900728
1687 1687 c, t dbSNP:199996352
1698 1698 a, g dbSNP:1141117
1704 1704 c, t dbSNP:1141118
1707 1707 c, t dbSNP:1141119
1710 1710 c, t dbSNP:1141120
1716 1716 c, g, t dbSNP:1141121
1720 1720 a, g dbSNP:146620441
1734 1734 c, t dbSNP:1064112
1737 1737 a, c dbSNP:763944667
1743 1743 c, t dbSNP:762743967
1747 1747 g, t dbSNP:145786768
1749 1749 c, g dbSNP:1064113
1752 1752 c, g dbSNP:1064114
1767 1767 c, g dbSNP:1064115
1781 1781 a, g dbSNP:765182656
1795 1795 a, g dbSNP:759053963
1798 1798 a, c dbSNP:776053336
1806 1806 a, c, t dbSNP:1141122
1809 1809 a, g dbSNP:1141123
1815 1815 a, t dbSNP:1141125
1821 1821 a, g dbSNP:1141126
1825 1825 c, t dbSNP:199855499
1831 1831 c, t dbSNP:769706649
1835 1835 g, t dbSNP:372641163
1842 1842 c, t dbSNP:1141127
1845 1845 c, t dbSNP:1141128
1853 1853 a, g dbSNP:781353111
1872 1872 a, c dbSNP:1141129
1875 1875 c, t dbSNP:1141131
1878 1878 c, t dbSNP:201555354
1892 1892 c, t dbSNP:754677708
1905 1905 c, t dbSNP:753693925
1908 1908 c, t dbSNP:146817483
1910 1910 a, t dbSNP:1064116
1915 1915 a, g, t dbSNP:749943696
1923 1923 a, g dbSNP:1064117
1935 1935 c, t dbSNP:1064118
1950 1950 a, g dbSNP:767204952
1953 1953 c, t dbSNP:1064119
1955 1955 c, t dbSNP:751201012
1971 1971 c, t dbSNP:1141144
1982 1982 c, t dbSNP:756779964
1998 1998 c, t dbSNP:1141145
2000 2000 a, t dbSNP:193922719
2004 2004 a, g dbSNP:370905622
2008 2008 a, g dbSNP:193922720
2011 2011 c, t dbSNP:149791519
2014 2014 a, g dbSNP:758127158
2018 2018 -, a dbSNP:33997807
2022 2022 a, g dbSNP:376413845
2026 2026 a, g dbSNP:765516506
2030 2030 a, g dbSNP:759905653
2034 2034 c, t dbSNP:777070160
2037 2037 a, g dbSNP:766899484
2052 2052 a, g dbSNP:1064120
2053 2053 a, c dbSNP:1064121
2055 2055 a, c dbSNP:1064122
2082 2082 c, t dbSNP:117691970
2083 2083 a, g dbSNP:773386939
2085 2085 a, c dbSNP:772174970
2094 2094 c, t dbSNP:748472407
2096 2096 g, t dbSNP:786205503
2106 2106 a, g dbSNP:774445141
2115 2115 c, t dbSNP:769658142
2137 2137 a, g dbSNP:113994139
2147 2147 a, t dbSNP:769031989
2148 2148 c, t dbSNP:751536580
2166 2166 c, g dbSNP:587777649
2168 2168 a, g, t dbSNP:770986654
2190 2190 c, t dbSNP:746896356
2196 2196 c, t dbSNP:777585143
2198 2198 a, g dbSNP:193922721
2202 2202 c, g dbSNP:587777650
2205 2205 c, t dbSNP:771560652
2209 2209 g, t dbSNP:747639500
2232 2232 c, t dbSNP:778501578
2250 2250 c, t dbSNP:754672701
2277 2277 c, t dbSNP:373256669
2278 2278 a, c, g dbSNP:780466766
2288 2288 a, g dbSNP:756441740
2310 2310 a, t dbSNP:139701269
2319 2319 a, t dbSNP:200529713
2329 2329 a, g dbSNP:747667389
2330 2330 c, g dbSNP:778450270
2359 2359 c, t dbSNP:193922722
2364 2364 a, g dbSNP:768290157
2375 2375 c, t dbSNP:587777647
2385 2385 a, g, t dbSNP:761802498
2387 2387 c, g dbSNP:774279920
2388 2388 a, c dbSNP:768099770
2393 2393 a, c dbSNP:748822559
2394 2394 c, g dbSNP:775171412
2399 2399 c, t dbSNP:769372865
2405 2405 c, t dbSNP:11547455
2425 2425 c, t dbSNP:746221967
2427 2427 a, g dbSNP:781470131
2443 2443 a, c dbSNP:757779747
2445 2445 c, t dbSNP:747460012
2448 2448 c, t dbSNP:778445506
2453 2453 g, t dbSNP:151033214
2463 2463 c, t dbSNP:376372615
2493 2493 c, t dbSNP:752248821
2506 2506 c, t dbSNP:142236792
2510 2510 c, t dbSNP:759106857
2513 2513 c, t dbSNP:140604473
2514 2514 a, g dbSNP:147202525
2517 2517 a, g dbSNP:368404940
2519 2519 a, g dbSNP:773766015
2520 2520 c, g, t dbSNP:145244024
2521 2521 a, g dbSNP:779485558
2524 2524 a, g dbSNP:183996904
2529 2529 c, t dbSNP:568695064
2541 2541 a, c dbSNP:749420271
2547 2547 a, g dbSNP:780221973
2550 2550 c, t dbSNP:374327257
2551 2551 a, g dbSNP:756380897
2564 2564 a, g dbSNP:368050581
2565 2565 -, g dbSNP:748972949
2569 2569 c, g, t dbSNP:374107124
2570 2570 a, g dbSNP:752520342
2573 2573 g, t dbSNP:7207492
2578 2578 c, t dbSNP:758935946
2579 2579 a, g dbSNP:557841793
2585 2585 c, t dbSNP:375752935
2594 2594 c, g dbSNP:368388401
2601 2601 c, t dbSNP:769563218
2661 2661 -, t dbSNP:201259337
2661 2661 a, t dbSNP:745710035
2692 2692 c, t dbSNP:1803126
2729 2729 a, c, g dbSNP:571072469
2749 2749 a, c dbSNP:41289087
2755 2755 a, g dbSNP:374525108
2770 2770 c, g dbSNP:530910704
2779 2779 a, g dbSNP:570130402
2786 2786 a, g dbSNP:548332594
2797 2797 a, g, t dbSNP:530088285
2799 2799 a, g dbSNP:561673659
2802 2802 -, g dbSNP:554015274
2834 2834 a, g dbSNP:746452227
2842 2842 a, g dbSNP:566824382
2857 2857 c, t dbSNP:117735406
2889 2889 -, gtt dbSNP:533596827
2906 2906 c, t dbSNP:113644902
2940 2940 a, g dbSNP:186798539
2945 2945 c, t dbSNP:777345728
2972 2972 -, a dbSNP:767787925
2973 2973 c, t dbSNP:540114461
2998 2998 c, t dbSNP:528332516
3048 3048 c, t dbSNP:563944808
3065 3065 c, t dbSNP:572165563
3073 3073 a, g dbSNP:569395714
3075 3075 a, g dbSNP:545977519
3079 3079 -, a dbSNP:368910594
3087 3087 c, t dbSNP:539172696
3120 3120 a, t dbSNP:115090026
3122 3122 g, t dbSNP:11079042
3147 3147 c, t dbSNP:759943258
3157 3157 a, c dbSNP:751996505
3207 3207 c, t dbSNP:138998960
3227 3227 a, c dbSNP:766973491
3268 3268 a, g dbSNP:555637030
3303 3303 a, g dbSNP:535612802
3320 3320 a, g dbSNP:552970845
3323 3323 g, t dbSNP:535347870
3336 3336 c, t dbSNP:577565516
3391 3391 a, g dbSNP:559241286
3401 3401 -, ga dbSNP:763595711
3431 3431 -, a dbSNP:754306251
3432 3432 -, g dbSNP:373212106
3433 3433 a, g dbSNP:537640981
3463 3463 -, t dbSNP:752673079
3481 3481 c, t dbSNP:367884098
3569 3569 a, g dbSNP:146907042
3613 3613 a, g dbSNP:536318793
3620 3620 g, t dbSNP:184030721
3652 3652 c, t dbSNP:569957236
3663 3663 a, g dbSNP:377364072
3703 3703 -, c dbSNP:35427318
3734 3734 c, t dbSNP:193126798
3767 3767 a, g dbSNP:112608032
3797 3797 c, t dbSNP:372716251
3798 3798 c, t dbSNP:149628743
3832 3832 g, t dbSNP:556139569
3846 3846 a, g dbSNP:756528147
3854 3854 a, g dbSNP:552123985
3863 3863 a, g dbSNP:3744483
3871 3871 c, t dbSNP:75018295
3887 3887 a, g dbSNP:541925122
3889 3889 a, c dbSNP:188588928
3920 3920 -, ag dbSNP:781243612
3921 3921 c, g dbSNP:183293865
3956 3956 c, t dbSNP:547767441
3959 3959 c, t dbSNP:541024608
3960 3960 a, g dbSNP:577652056
3963 3963 a, g dbSNP:559186748
3994 3994 c, t dbSNP:537273486
4001 4001 c, t dbSNP:576595680
4030 4030 a, g dbSNP:554827097
4035 4035 a, g dbSNP:190710939
4055 4055 a, g dbSNP:75454844
4075 4075 a, c dbSNP:185508151
4137 4137 a, c dbSNP:763077835
4142 4142 g, t dbSNP:111904020
4145 4145 g, t dbSNP:547430088
4166 4166 c, g dbSNP:182824638
4209 4209 c, t dbSNP:1053004
4231 4231 a, g dbSNP:373503231
4276 4276 c, g dbSNP:552467234
4279 4279 a, g dbSNP:530683057
4287 4287 c, t dbSNP:769760865
4372 4372 g, t dbSNP:10775
4379 4379 c, t dbSNP:376764794
4391 4391 a, g dbSNP:1053005
4406 4406 a, g dbSNP:548033008
4469 4469 a, g dbSNP:138326799
4539 4539 g, t dbSNP:150467429
4540 4540 a, g dbSNP:531760487
4548 4548 c, t dbSNP:541059766
4552 4552 a, g dbSNP:532120833
4609 4609 c, g dbSNP:564695836
4685 4685 a, g dbSNP:1053023
4755 4755 a, g dbSNP:576615644
4796 4796 -, t dbSNP:751300490
4859 4859 a, g dbSNP:762995262
4869 4869 a, g dbSNP:555195129
4881 4881 -, gtc dbSNP:773939681
4881 4881 c, t dbSNP:200029754
4882 4882 -, t dbSNP:398041696
4883 4883 c, t dbSNP:80323123
4902 4902 -, tt dbSNP:760910438
4903 4903 -, t dbSNP:397857989
4904 4904 g, t dbSNP:147045863

Target ORF information:

RefSeq Version XM_005257616
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens signal transducer and activator of transcription 3 (acute-phase response factor) (STAT3), transcript variant X3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_005257616

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
ATGGCCCAAT GGAATCAGCT ACAGCAGCTT GACACACGGT ACCTGGAGCA GCTCCATCAG 
CTCTACAGTG ACAGCTTCCC AATGGAGCTG CGGCAGTTTC TGGCCCCTTG GATTGAGAGT
CAAGATTGGG CATATGCGGC CAGCAAAGAA TCACATGCCA CTTTGGTGTT TCATAATCTC
CTGGGAGAGA TTGACCAGCA GTATAGCCGC TTCCTGCAAG AGTCGAATGT TCTCTATCAG
CACAATCTAC GAAGAATCAA GCAGTTTCTT CAGAGCAGGT ATCTTGAGAA GCCAATGGAG
ATTGCCCGGA TTGTGGCCCG GTGCCTGTGG GAAGAATCAC GCCTTCTACA GACTGCAGCC
ACTGCGGCCC AGCAAGGGGG CCAGGCCAAC CACCCCACAG CAGCCGTGGT GACGGAGAAG
CAGCAGATGC TGGAGCAGCA CCTTCAGGAT GTCCGGAAGA GAGTGCAGGA TCTAGAACAG
AAAATGAAAG TGGTAGAGAA TCTCCAGGAT GACTTTGATT TCAACTATAA AACCCTCAAG
AGTCAAGGAG ACATGCAAGA TCTGAATGGA AACAACCAGT CAGTGACCAG GCAGAAGATG
CAGCAGCTGG AACAGATGCT CACTGCGCTG GACCAGATGC GGAGAAGCAT CGTGAGTGAG
CTGGCGGGGC TTTTGTCAGC GATGGAGTAC GTGCAGAAAA CTCTCACGGA CGAGGAGCTG
GCTGACTGGA AGAGGCGGCA ACAGATTGCC TGCATTGGAG GCCCGCCCAA CATCTGCCTA
GATCGGCTAG AAAACTGGAT AACGTCATTA GCAGAATCTC AACTTCAGAC CCGTCAACAA
ATTAAGAAAC TGGAGGAGTT GCAGCAAAAA GTTTCCTACA AAGGGGACCC CATTGTACAG
CACCGGCCGA TGCTGGAGGA GAGAATCGTG GAGCTGTTTA GAAACTTAAT GAAAAGTGCC
TTTGTGGTGG AGCGGCAGCC CTGCATGCCC ATGCATCCTG ACCGGCCCCT CGTCATCAAG
ACCGGCGTCC AGTTCACTAC TAAAGTCAGG TTGCTGGTCA AATTCCCTGA GTTGAATTAT
CAGCTTAAAA TTAAAGTGTG CATTGACAAA GACTCTGGGG ACGTTGCAGC TCTCAGAGGA
TCCCGGAAAT TTAACATTCT GGGCACAAAC ACAAAAGTGA TGAACATGGA AGAATCCAAC
AACGGCAGCC TCTCTGCAGA ATTCAAACAC TTGACCCTGA GGGAGCAGAG ATGTGGGAAT
GGGGGCCGAG CCAATTGTGA TGCTTCCCTG ATTGTGACTG AGGAGCTGCA CCTGATCACC
TTTGAGACCG AGGTGTATCA CCAAGGCCTC AAGATTGACC TAGAGACCCA CTCCTTGCCA
GTTGTGGTGA TCTCCAACAT CTGTCAGATG CCAAATGCCT GGGCGTCCAT CCTGTGGTAC
AACATGCTGA CCAACAATCC CAAGAATGTA AACTTTTTTA CCAAGCCCCC AATTGGAACC
TGGGATCAAG TGGCCGAGGT CCTGAGCTGG CAGTTCTCCT CCACCACCAA GCGAGGACTG
AGCATCGAGC AGCTGACTAC ACTGGCAGAG AAACTCTTGG GACCTGGTGT GAATTATTCA
GGGTGTCAGA TCACATGGGC TAAATTTTGC AAAGAAAACA TGGCTGGCAA GGGCTTCTCC
TTCTGGGTCT GGCTGGACAA TATCATTGAC CTTGTGAAAA AGTACATCCT GGCCCTTTGG
AACGAAGGGT ACATCATGGG CTTTATCAGT AAGGAGCGGG AGCGGGCCAT CTTGAGCACT
AAGCCTCCAG GCACCTTCCT GCTAAGATTC AGTGAAAGCA GCAAAGAAGG AGGCGTCACT
TTCACTTGGG TGGAGAAGGA CATCAGCGGT AAGACCCAGA TCCAGTCCGT GGAACCATAC
ACAAAGCAGC AGCTGAACAA CATGTCATTT GCTGAAATCA TCATGGGCTA TAAGATCATG
GATGCTACCA ATATCCTGGT GTCTCCACTG GTCTATCTCT ATCCTGACAT TCCCAAGGAG
GAGGCATTCG GAAAGTATTG TCGGCCAGAG AGCCAGGAGC ATCCTGAAGC TGACCCAGGC
GCTGCCCCAT ACCTGAAGAC CAAGTTTATC TGTGTGACAC CAACGACCTG CAGCAATACC
ATTGACCTGC CGATGTCCCC CCGCACTTTA GATTCATTGA TGCAGTTTGG AAATAATGGT
GAAGGTGCTG AACCCTCAGC AGGAGGGCAG TTTGAGTCCC TCACCTTTGA CATGGAGTTG
ACCTCGGAGT GCGCTACCTC CCCCATGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu26606
Accession Version XM_011525146.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 2169bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector Document: User manual_GenEZ ORF Clone Products.pdf (pdf)
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags Document: MSDS_GenEZ ORF Clone Products.pdf (pdf)
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product signal transducer and activator of transcription 3 isoform X3
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_010783.16) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
ATGGCCCAAT GGAATCAGCT ACAGCAGCTT GACACACGGT ACCTGGAGCA GCTCCATCAG 
CTCTACAGTG ACAGCTTCCC AATGGAGCTG CGGCAGTTTC TGGCCCCTTG GATTGAGAGT
CAAGATTGGG CATATGCGGC CAGCAAAGAA TCACATGCCA CTTTGGTGTT TCATAATCTC
CTGGGAGAGA TTGACCAGCA GTATAGCCGC TTCCTGCAAG AGTCGAATGT TCTCTATCAG
CACAATCTAC GAAGAATCAA GCAGTTTCTT CAGAGCAGGT ATCTTGAGAA GCCAATGGAG
ATTGCCCGGA TTGTGGCCCG GTGCCTGTGG GAAGAATCAC GCCTTCTACA GACTGCAGCC
ACTGCGGCCC AGCAAGGGGG CCAGGCCAAC CACCCCACAG CAGCCGTGGT GACGGAGAAG
CAGCAGATGC TGGAGCAGCA CCTTCAGGAT GTCCGGAAGA GAGTGCAGGA TCTAGAACAG
AAAATGAAAG TGGTAGAGAA TCTCCAGGAT GACTTTGATT TCAACTATAA AACCCTCAAG
AGTCAAGGAG ACATGCAAGA TCTGAATGGA AACAACCAGT CAGTGACCAG GCAGAAGATG
CAGCAGCTGG AACAGATGCT CACTGCGCTG GACCAGATGC GGAGAAGCAT CGTGAGTGAG
CTGGCGGGGC TTTTGTCAGC GATGGAGTAC GTGCAGAAAA CTCTCACGGA CGAGGAGCTG
GCTGACTGGA AGAGGCGGCA ACAGATTGCC TGCATTGGAG GCCCGCCCAA CATCTGCCTA
GATCGGCTAG AAAACTGGAT AACGTCATTA GCAGAATCTC AACTTCAGAC CCGTCAACAA
ATTAAGAAAC TGGAGGAGTT GCAGCAAAAA GTTTCCTACA AAGGGGACCC CATTGTACAG
CACCGGCCGA TGCTGGAGGA GAGAATCGTG GAGCTGTTTA GAAACTTAAT GAAAAGTGCC
TTTGTGGTGG AGCGGCAGCC CTGCATGCCC ATGCATCCTG ACCGGCCCCT CGTCATCAAG
ACCGGCGTCC AGTTCACTAC TAAAGTCAGG TTGCTGGTCA AATTCCCTGA GTTGAATTAT
CAGCTTAAAA TTAAAGTGTG CATTGACAAA GACTCTGGGG ACGTTGCAGC TCTCAGAGGA
TCCCGGAAAT TTAACATTCT GGGCACAAAC ACAAAAGTGA TGAACATGGA AGAATCCAAC
AACGGCAGCC TCTCTGCAGA ATTCAAACAC TTGACCCTGA GGGAGCAGAG ATGTGGGAAT
GGGGGCCGAG CCAATTGTGA TGCTTCCCTG ATTGTGACTG AGGAGCTGCA CCTGATCACC
TTTGAGACCG AGGTGTATCA CCAAGGCCTC AAGATTGACC TAGAGACCCA CTCCTTGCCA
GTTGTGGTGA TCTCCAACAT CTGTCAGATG CCAAATGCCT GGGCGTCCAT CCTGTGGTAC
AACATGCTGA CCAACAATCC CAAGAATGTA AACTTTTTTA CCAAGCCCCC AATTGGAACC
TGGGATCAAG TGGCCGAGGT CCTGAGCTGG CAGTTCTCCT CCACCACCAA GCGAGGACTG
AGCATCGAGC AGCTGACTAC ACTGGCAGAG AAACTCTTGG GACCTGGTGT GAATTATTCA
GGGTGTCAGA TCACATGGGC TAAATTTTGC AAAGAAAACA TGGCTGGCAA GGGCTTCTCC
TTCTGGGTCT GGCTGGACAA TATCATTGAC CTTGTGAAAA AGTACATCCT GGCCCTTTGG
AACGAAGGGT ACATCATGGG CTTTATCAGT AAGGAGCGGG AGCGGGCCAT CTTGAGCACT
AAGCCTCCAG GCACCTTCCT GCTAAGATTC AGTGAAAGCA GCAAAGAAGG AGGCGTCACT
TTCACTTGGG TGGAGAAGGA CATCAGCGGT AAGACCCAGA TCCAGTCCGT GGAACCATAC
ACAAAGCAGC AGCTGAACAA CATGTCATTT GCTGAAATCA TCATGGGCTA TAAGATCATG
GATGCTACCA ATATCCTGGT GTCTCCACTG GTCTATCTCT ATCCTGACAT TCCCAAGGAG
GAGGCATTCG GAAAGTATTG TCGGCCAGAG AGCCAGGAGC ATCCTGAAGC TGACCCAGGT
AGCGCTGCCC CATACCTGAA GACCAAGTTT ATCTGTGTGA CACCATTCAT TGATGCAGTT
TGGAAATAA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqXP_011523448.1
CDS229..2397
Misc Feature(1)232..588(+)
Misc Feature(2)643..1185(+)
Misc Feature(3)1189..1950(+)
Misc Feature(4)1888..2373(+)
Misc Feature(5)1999..2142(+)
Misc Feature(6)2137..2187(+)
Misc Feature(7)2167..2358(+)
Translation
Position Chain Variation Link
13 13 c, g dbSNP:765882801
41 41 c, g dbSNP:566151688
44 44 c, g dbSNP:547925260
53 53 c, g dbSNP:780393027
83 83 c, t dbSNP:760179821
108 108 c, t dbSNP:528219097
109 109 a, g dbSNP:17883843
226 226 a, g dbSNP:779793392
228 228 c, g dbSNP:756099567
237 237 a, g dbSNP:749859511
266 266 a, g dbSNP:780720013
276 276 a, g dbSNP:563996007
291 291 c, g dbSNP:541045758
298 298 a, g dbSNP:751281347
300 300 c, t dbSNP:763742034
322 322 a, c dbSNP:1803125
327 327 c, t dbSNP:758631901
331 331 g, t dbSNP:748204289
363 363 a, c, t dbSNP:766994331
366 366 a, g dbSNP:760775429
371 371 a, g, t dbSNP:766875947
375 375 a, g dbSNP:767594035
387 387 c, t dbSNP:762135443
422 422 a, g dbSNP:775122881
424 424 c, g dbSNP:375760579
441 441 c, t dbSNP:530451908
453 453 a, g dbSNP:146184566
473 473 a, g dbSNP:776494537
475 475 c, t dbSNP:770878694
481 481 a, c dbSNP:746486285
531 531 c, t dbSNP:747612981
537 537 a, c, g dbSNP:17880940
548 548 a, g dbSNP:749626783
551 551 a, g dbSNP:780604324
555 555 g, t dbSNP:759676110
561 561 a, g dbSNP:750994809
564 564 a, g dbSNP:200440712
576 576 a, g dbSNP:200960081
580 580 a, t dbSNP:757305223
589 589 a, t dbSNP:751614036
591 591 a, t dbSNP:764338385
593 593 c, t dbSNP:774724351
601 601 c, g dbSNP:574370336
603 603 a, g dbSNP:747081170
605 605 a, g dbSNP:777883261
609 609 c, t dbSNP:758609919
633 633 c, t dbSNP:201846078
642 642 a, g dbSNP:765452694
648 648 a, g dbSNP:755877110
654 654 a, g dbSNP:774823374
657 657 a, g dbSNP:17878478
658 658 c, t dbSNP:761693018
663 663 a, g dbSNP:773889504
676 676 -, g dbSNP:35332755
741 741 c, t dbSNP:777828006
751 751 a, c dbSNP:758408552
763 763 c, t dbSNP:748237742
765 765 c, t dbSNP:779055365
779 779 a, g dbSNP:748184550
780 780 c, t dbSNP:202126764
786 786 a, g dbSNP:768898076
790 790 a, c dbSNP:749529243
795 795 a, t dbSNP:781034418
798 798 a, t dbSNP:756935531
815 815 a, c dbSNP:751411956
822 822 c, g dbSNP:374063766
849 849 c, t dbSNP:758449863
852 852 c, t dbSNP:752235250
855 855 a, c, g dbSNP:759225787
871 871 a, g dbSNP:753370239
879 879 c, t dbSNP:377095381
884 884 a, g dbSNP:762301765
888 888 a, g dbSNP:774652472
893 893 c, t dbSNP:764674735
894 894 a, g dbSNP:762891098
909 909 a, g dbSNP:775680553
915 915 a, g dbSNP:769885072
918 918 c, t dbSNP:746151758
921 921 g, t dbSNP:374524373
934 934 a, t dbSNP:773138024
935 935 c, g dbSNP:371541785
937 937 a, g dbSNP:376677265
939 939 c, t dbSNP:17882069
946 946 c, t dbSNP:754971639
951 951 a, c, t dbSNP:139588729
954 954 a, c dbSNP:755746762
967 967 c, t dbSNP:750141391
971 971 a, c dbSNP:757347742
974 974 c, t dbSNP:767159289
993 993 a, g dbSNP:527634708
1006 1006 c, g, t dbSNP:764478072
1018 1018 a, g dbSNP:763564047
1023 1023 a, c dbSNP:775421377
1027 1027 a, g dbSNP:749302989
1031 1031 a, c dbSNP:779422770
1032 1032 a, g dbSNP:755554248
1045 1045 c, t dbSNP:745393806
1050 1050 a, g dbSNP:780773507
1053 1053 g, t dbSNP:200098006
1062 1062 c, t dbSNP:751849047
1092 1092 c, g dbSNP:1064110
1107 1107 c, t dbSNP:147186377
1137 1137 a, g dbSNP:764577805
1141 1141 c, t dbSNP:758828674
1152 1152 a, g dbSNP:1064111
1155 1155 c, t dbSNP:779733888
1156 1156 a, g dbSNP:765856200
1167 1167 c, t dbSNP:1141111
1207 1207 c, g dbSNP:759527569
1231 1231 c, t dbSNP:193922716
1232 1232 a, g dbSNP:776115471
1239 1239 c, t dbSNP:200623682
1240 1240 a, g dbSNP:371953916
1251 1251 c, t dbSNP:777436789
1254 1254 c, t dbSNP:539947939
1267 1267 a, g dbSNP:748496600
1273 1273 a, g dbSNP:368454926
1275 1275 c, t dbSNP:779464807
1277 1277 g, t dbSNP:755524497
1278 1278 a, g dbSNP:771738153
1281 1281 a, g dbSNP:201472943
1287 1287 c, t dbSNP:774847480
1290 1290 a, g dbSNP:1141112
1301 1301 g, t dbSNP:769072802
1344 1344 c, t dbSNP:770311773
1350 1350 c, t dbSNP:376080249
1351 1351 a, g dbSNP:781724933
1355 1355 c, t dbSNP:373083464
1371 1371 c, g dbSNP:143571879
1372 1372 c, t dbSNP:113994135
1373 1373 a, g, t dbSNP:113994136
1394 1394 c, t dbSNP:397514766
1397 1397 a, g dbSNP:566350932
1403 1403 a, g dbSNP:587777648
1428 1428 c, t dbSNP:757298594
1431 1431 c, t dbSNP:189708970
1432 1432 a, g dbSNP:763754846
1443 1443 c, t dbSNP:769971732
1458 1458 c, t dbSNP:138001349
1465 1465 c, t dbSNP:146946014
1471 1471 a, g dbSNP:193922717
1473 1473 a, g dbSNP:184867029
1491 1491 a, g dbSNP:141151719
1496 1496 a, g dbSNP:113994137
1499 1499 c, t dbSNP:768739455
1508 1508 a, g dbSNP:749583802
1512 1512 c, t dbSNP:775806195
1548 1548 c, g dbSNP:770170991
1557 1557 a, c, t dbSNP:147955721
1559 1559 a, c dbSNP:771888821
1560 1560 a, g dbSNP:748180243
1572 1572 a, g dbSNP:778716670
1575 1575 c, t dbSNP:1141115
1579 1579 a, c dbSNP:768150168
1589 1589 c, t dbSNP:748564923
1591 1591 g, t dbSNP:34460718
1596 1596 a, c, t dbSNP:769425072
1606 1606 c, t dbSNP:1141116
1609 1609 c, g dbSNP:149214040
1615 1615 -, gtg dbSNP:113994138
1653 1653 a, g dbSNP:780713214
1656 1656 c, t dbSNP:369714894
1683 1683 a, c dbSNP:751900728
1687 1687 c, t dbSNP:199996352
1698 1698 a, g dbSNP:1141117
1704 1704 c, t dbSNP:1141118
1707 1707 c, t dbSNP:1141119
1710 1710 c, t dbSNP:1141120
1716 1716 c, g, t dbSNP:1141121
1720 1720 a, g dbSNP:146620441
1734 1734 c, t dbSNP:1064112
1737 1737 a, c dbSNP:763944667
1743 1743 c, t dbSNP:762743967
1747 1747 g, t dbSNP:145786768
1749 1749 c, g dbSNP:1064113
1752 1752 c, g dbSNP:1064114
1767 1767 c, g dbSNP:1064115
1781 1781 a, g dbSNP:765182656
1795 1795 a, g dbSNP:759053963
1798 1798 a, c dbSNP:776053336
1806 1806 a, c, t dbSNP:1141122
1809 1809 a, g dbSNP:1141123
1815 1815 a, t dbSNP:1141125
1821 1821 a, g dbSNP:1141126
1825 1825 c, t dbSNP:199855499
1831 1831 c, t dbSNP:769706649
1835 1835 g, t dbSNP:372641163
1842 1842 c, t dbSNP:1141127
1845 1845 c, t dbSNP:1141128
1853 1853 a, g dbSNP:781353111
1872 1872 a, c dbSNP:1141129
1875 1875 c, t dbSNP:1141131
1878 1878 c, t dbSNP:201555354
1892 1892 c, t dbSNP:754677708
1905 1905 c, t dbSNP:753693925
1908 1908 c, t dbSNP:146817483
1910 1910 a, t dbSNP:1064116
1915 1915 a, g, t dbSNP:749943696
1923 1923 a, g dbSNP:1064117
1935 1935 c, t dbSNP:1064118
1950 1950 a, g dbSNP:767204952
1953 1953 c, t dbSNP:1064119
1955 1955 c, t dbSNP:751201012
1971 1971 c, t dbSNP:1141144
1982 1982 c, t dbSNP:756779964
1998 1998 c, t dbSNP:1141145
2000 2000 a, t dbSNP:193922719
2004 2004 a, g dbSNP:370905622
2008 2008 a, g dbSNP:193922720
2011 2011 c, t dbSNP:149791519
2014 2014 a, g dbSNP:758127158
2018 2018 -, a dbSNP:33997807
2022 2022 a, g dbSNP:376413845
2026 2026 a, g dbSNP:765516506
2030 2030 a, g dbSNP:759905653
2034 2034 c, t dbSNP:777070160
2037 2037 a, g dbSNP:766899484
2052 2052 a, g dbSNP:1064120
2053 2053 a, c dbSNP:1064121
2055 2055 a, c dbSNP:1064122
2082 2082 c, t dbSNP:117691970
2083 2083 a, g dbSNP:773386939
2085 2085 a, c dbSNP:772174970
2094 2094 c, t dbSNP:748472407
2096 2096 g, t dbSNP:786205503
2106 2106 a, g dbSNP:774445141
2115 2115 c, t dbSNP:769658142
2137 2137 a, g dbSNP:113994139
2147 2147 a, t dbSNP:769031989
2148 2148 c, t dbSNP:751536580
2166 2166 c, g dbSNP:587777649
2168 2168 a, g, t dbSNP:770986654
2190 2190 c, t dbSNP:746896356
2196 2196 c, t dbSNP:777585143
2198 2198 a, g dbSNP:193922721
2202 2202 c, g dbSNP:587777650
2205 2205 c, t dbSNP:771560652
2209 2209 g, t dbSNP:747639500
2232 2232 c, t dbSNP:778501578
2250 2250 c, t dbSNP:754672701
2277 2277 c, t dbSNP:373256669
2278 2278 a, c, g dbSNP:780466766
2288 2288 a, g dbSNP:756441740
2310 2310 a, t dbSNP:139701269
2319 2319 a, t dbSNP:200529713
2332 2332 a, g dbSNP:747667389
2333 2333 c, g dbSNP:778450270
2362 2362 c, t dbSNP:193922722
2367 2367 a, g dbSNP:768290157
2378 2378 c, t dbSNP:746221967
2380 2380 a, g dbSNP:781470131
2396 2396 a, c dbSNP:757779747
2398 2398 c, t dbSNP:747460012
2401 2401 c, t dbSNP:778445506
2406 2406 g, t dbSNP:151033214
2416 2416 c, t dbSNP:376372615
2446 2446 c, t dbSNP:752248821
2459 2459 c, t dbSNP:142236792
2463 2463 c, t dbSNP:759106857
2466 2466 c, t dbSNP:140604473
2467 2467 a, g dbSNP:147202525
2470 2470 a, g dbSNP:368404940
2472 2472 a, g dbSNP:773766015
2473 2473 c, g, t dbSNP:145244024
2474 2474 a, g dbSNP:779485558
2477 2477 a, g dbSNP:183996904
2482 2482 c, t dbSNP:568695064
2494 2494 a, c dbSNP:749420271
2500 2500 a, g dbSNP:780221973
2503 2503 c, t dbSNP:374327257
2504 2504 a, g dbSNP:756380897
2517 2517 a, g dbSNP:368050581
2518 2518 -, g dbSNP:748972949
2522 2522 c, g, t dbSNP:374107124
2523 2523 a, g dbSNP:752520342
2526 2526 g, t dbSNP:7207492
2531 2531 c, t dbSNP:758935946
2532 2532 a, g dbSNP:557841793
2538 2538 c, t dbSNP:375752935
2547 2547 c, g dbSNP:368388401
2554 2554 c, t dbSNP:769563218
2614 2614 -, t dbSNP:201259337
2614 2614 a, t dbSNP:745710035
2645 2645 c, t dbSNP:1803126
2682 2682 a, c, g dbSNP:571072469
2702 2702 a, c dbSNP:41289087
2708 2708 a, g dbSNP:374525108
2723 2723 c, g dbSNP:530910704
2732 2732 a, g dbSNP:570130402
2739 2739 a, g dbSNP:548332594
2750 2750 a, g, t dbSNP:530088285
2752 2752 a, g dbSNP:561673659
2755 2755 -, g dbSNP:554015274
2787 2787 a, g dbSNP:746452227
2795 2795 a, g dbSNP:566824382
2810 2810 c, t dbSNP:117735406
2842 2842 -, gtt dbSNP:533596827
2859 2859 c, t dbSNP:113644902
2893 2893 a, g dbSNP:186798539
2898 2898 c, t dbSNP:777345728
2925 2925 -, a dbSNP:767787925
2926 2926 c, t dbSNP:540114461
2951 2951 c, t dbSNP:528332516
3001 3001 c, t dbSNP:563944808
3018 3018 c, t dbSNP:572165563
3026 3026 a, g dbSNP:569395714
3028 3028 a, g dbSNP:545977519
3032 3032 -, a dbSNP:368910594
3040 3040 c, t dbSNP:539172696
3073 3073 a, t dbSNP:115090026
3075 3075 g, t dbSNP:11079042
3100 3100 c, t dbSNP:759943258
3110 3110 a, c dbSNP:751996505
3160 3160 c, t dbSNP:138998960
3180 3180 a, c dbSNP:766973491
3221 3221 a, g dbSNP:555637030
3256 3256 a, g dbSNP:535612802
3273 3273 a, g dbSNP:552970845
3276 3276 g, t dbSNP:535347870
3289 3289 c, t dbSNP:577565516
3344 3344 a, g dbSNP:559241286
3354 3354 -, ga dbSNP:763595711
3384 3384 -, a dbSNP:754306251
3385 3385 -, g dbSNP:373212106
3386 3386 a, g dbSNP:537640981
3416 3416 -, t dbSNP:752673079
3434 3434 c, t dbSNP:367884098
3522 3522 a, g dbSNP:146907042
3566 3566 a, g dbSNP:536318793
3573 3573 g, t dbSNP:184030721
3605 3605 c, t dbSNP:569957236
3616 3616 a, g dbSNP:377364072
3656 3656 -, c dbSNP:35427318
3687 3687 c, t dbSNP:193126798
3720 3720 a, g dbSNP:112608032
3750 3750 c, t dbSNP:372716251
3751 3751 c, t dbSNP:149628743
3785 3785 g, t dbSNP:556139569
3799 3799 a, g dbSNP:756528147
3807 3807 a, g dbSNP:552123985
3816 3816 a, g dbSNP:3744483
3824 3824 c, t dbSNP:75018295
3840 3840 a, g dbSNP:541925122
3842 3842 a, c dbSNP:188588928
3873 3873 -, ag dbSNP:781243612
3874 3874 c, g dbSNP:183293865
3909 3909 c, t dbSNP:547767441
3912 3912 c, t dbSNP:541024608
3913 3913 a, g dbSNP:577652056
3916 3916 a, g dbSNP:559186748
3947 3947 c, t dbSNP:537273486
3954 3954 c, t dbSNP:576595680
3983 3983 a, g dbSNP:554827097
3988 3988 a, g dbSNP:190710939
4008 4008 a, g dbSNP:75454844
4028 4028 a, c dbSNP:185508151
4090 4090 a, c dbSNP:763077835
4095 4095 g, t dbSNP:111904020
4098 4098 g, t dbSNP:547430088
4119 4119 c, g dbSNP:182824638
4162 4162 c, t dbSNP:1053004
4184 4184 a, g dbSNP:373503231
4229 4229 c, g dbSNP:552467234
4232 4232 a, g dbSNP:530683057
4240 4240 c, t dbSNP:769760865
4325 4325 g, t dbSNP:10775
4332 4332 c, t dbSNP:376764794
4344 4344 a, g dbSNP:1053005
4359 4359 a, g dbSNP:548033008
4422 4422 a, g dbSNP:138326799
4492 4492 g, t dbSNP:150467429
4493 4493 a, g dbSNP:531760487
4501 4501 c, t dbSNP:541059766
4505 4505 a, g dbSNP:532120833
4562 4562 c, g dbSNP:564695836
4638 4638 a, g dbSNP:1053023
4708 4708 a, g dbSNP:576615644
4749 4749 -, t dbSNP:751300490
4812 4812 a, g dbSNP:762995262
4822 4822 a, g dbSNP:555195129
4834 4834 -, gtc dbSNP:773939681
4834 4834 c, t dbSNP:200029754
4835 4835 -, t dbSNP:398041696
4836 4836 c, t dbSNP:80323123
4855 4855 -, tt dbSNP:760910438
4856 4856 -, t dbSNP:397857989
4857 4857 g, t dbSNP:147045863

Target ORF information:

RefSeq Version XM_011525146
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens signal transducer and activator of transcription 3 (acute-phase response factor) (STAT3), transcript variant X4, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011525146

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
ATGGCCCAAT GGAATCAGCT ACAGCAGCTT GACACACGGT ACCTGGAGCA GCTCCATCAG 
CTCTACAGTG ACAGCTTCCC AATGGAGCTG CGGCAGTTTC TGGCCCCTTG GATTGAGAGT
CAAGATTGGG CATATGCGGC CAGCAAAGAA TCACATGCCA CTTTGGTGTT TCATAATCTC
CTGGGAGAGA TTGACCAGCA GTATAGCCGC TTCCTGCAAG AGTCGAATGT TCTCTATCAG
CACAATCTAC GAAGAATCAA GCAGTTTCTT CAGAGCAGGT ATCTTGAGAA GCCAATGGAG
ATTGCCCGGA TTGTGGCCCG GTGCCTGTGG GAAGAATCAC GCCTTCTACA GACTGCAGCC
ACTGCGGCCC AGCAAGGGGG CCAGGCCAAC CACCCCACAG CAGCCGTGGT GACGGAGAAG
CAGCAGATGC TGGAGCAGCA CCTTCAGGAT GTCCGGAAGA GAGTGCAGGA TCTAGAACAG
AAAATGAAAG TGGTAGAGAA TCTCCAGGAT GACTTTGATT TCAACTATAA AACCCTCAAG
AGTCAAGGAG ACATGCAAGA TCTGAATGGA AACAACCAGT CAGTGACCAG GCAGAAGATG
CAGCAGCTGG AACAGATGCT CACTGCGCTG GACCAGATGC GGAGAAGCAT CGTGAGTGAG
CTGGCGGGGC TTTTGTCAGC GATGGAGTAC GTGCAGAAAA CTCTCACGGA CGAGGAGCTG
GCTGACTGGA AGAGGCGGCA ACAGATTGCC TGCATTGGAG GCCCGCCCAA CATCTGCCTA
GATCGGCTAG AAAACTGGAT AACGTCATTA GCAGAATCTC AACTTCAGAC CCGTCAACAA
ATTAAGAAAC TGGAGGAGTT GCAGCAAAAA GTTTCCTACA AAGGGGACCC CATTGTACAG
CACCGGCCGA TGCTGGAGGA GAGAATCGTG GAGCTGTTTA GAAACTTAAT GAAAAGTGCC
TTTGTGGTGG AGCGGCAGCC CTGCATGCCC ATGCATCCTG ACCGGCCCCT CGTCATCAAG
ACCGGCGTCC AGTTCACTAC TAAAGTCAGG TTGCTGGTCA AATTCCCTGA GTTGAATTAT
CAGCTTAAAA TTAAAGTGTG CATTGACAAA GACTCTGGGG ACGTTGCAGC TCTCAGAGGA
TCCCGGAAAT TTAACATTCT GGGCACAAAC ACAAAAGTGA TGAACATGGA AGAATCCAAC
AACGGCAGCC TCTCTGCAGA ATTCAAACAC TTGACCCTGA GGGAGCAGAG ATGTGGGAAT
GGGGGCCGAG CCAATTGTGA TGCTTCCCTG ATTGTGACTG AGGAGCTGCA CCTGATCACC
TTTGAGACCG AGGTGTATCA CCAAGGCCTC AAGATTGACC TAGAGACCCA CTCCTTGCCA
GTTGTGGTGA TCTCCAACAT CTGTCAGATG CCAAATGCCT GGGCGTCCAT CCTGTGGTAC
AACATGCTGA CCAACAATCC CAAGAATGTA AACTTTTTTA CCAAGCCCCC AATTGGAACC
TGGGATCAAG TGGCCGAGGT CCTGAGCTGG CAGTTCTCCT CCACCACCAA GCGAGGACTG
AGCATCGAGC AGCTGACTAC ACTGGCAGAG AAACTCTTGG GACCTGGTGT GAATTATTCA
GGGTGTCAGA TCACATGGGC TAAATTTTGC AAAGAAAACA TGGCTGGCAA GGGCTTCTCC
TTCTGGGTCT GGCTGGACAA TATCATTGAC CTTGTGAAAA AGTACATCCT GGCCCTTTGG
AACGAAGGGT ACATCATGGG CTTTATCAGT AAGGAGCGGG AGCGGGCCAT CTTGAGCACT
AAGCCTCCAG GCACCTTCCT GCTAAGATTC AGTGAAAGCA GCAAAGAAGG AGGCGTCACT
TTCACTTGGG TGGAGAAGGA CATCAGCGGT AAGACCCAGA TCCAGTCCGT GGAACCATAC
ACAAAGCAGC AGCTGAACAA CATGTCATTT GCTGAAATCA TCATGGGCTA TAAGATCATG
GATGCTACCA ATATCCTGGT GTCTCCACTG GTCTATCTCT ATCCTGACAT TCCCAAGGAG
GAGGCATTCG GAAAGTATTG TCGGCCAGAG AGCCAGGAGC ATCCTGAAGC TGACCCAGGT
AGCGCTGCCC CATACCTGAA GACCAAGTTT ATCTGTGTGA CACCATTCAT TGATGCAGTT
TGGAAATAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu26660
Accession Version NM_139276.2 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 2313bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector Document: User manual_GenEZ ORF Clone Products.pdf (pdf)
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags Document: MSDS_GenEZ ORF Clone Products.pdf (pdf)
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear Document: OHu26660D_COA.pdf (pdf)
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product signal transducer and activator of transcription 3 isoform 1
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BI461226.1, BC014482.1, AK092965.1, CB216860.1, BC008044.2, CF454565.1 and AI631896.1. This sequence is a reference standard in the RefSeqGene project. On or before May 7, 2004 this sequence version replaced gi:16596687, gi:21618339. Summary: The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. This protein mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis. The small GTPase Rac1 has been shown to bind and regulate the activity of this protein. PIAS3 protein is a specific inhibitor of this protein. Three alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]. Transcript Variant: This variant (1) represents the longest transcript, and encodes the longest isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC014482.1, AK291933.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
ATGGCCCAAT GGAATCAGCT ACAGCAGCTT GACACACGGT ACCTGGAGCA GCTCCATCAG 
CTCTACAGTG ACAGCTTCCC AATGGAGCTG CGGCAGTTTC TGGCCCCTTG GATTGAGAGT
CAAGATTGGG CATATGCGGC CAGCAAAGAA TCACATGCCA CTTTGGTGTT TCATAATCTC
CTGGGAGAGA TTGACCAGCA GTATAGCCGC TTCCTGCAAG AGTCGAATGT TCTCTATCAG
CACAATCTAC GAAGAATCAA GCAGTTTCTT CAGAGCAGGT ATCTTGAGAA GCCAATGGAG
ATTGCCCGGA TTGTGGCCCG GTGCCTGTGG GAAGAATCAC GCCTTCTACA GACTGCAGCC
ACTGCGGCCC AGCAAGGGGG CCAGGCCAAC CACCCCACAG CAGCCGTGGT GACGGAGAAG
CAGCAGATGC TGGAGCAGCA CCTTCAGGAT GTCCGGAAGA GAGTGCAGGA TCTAGAACAG
AAAATGAAAG TGGTAGAGAA TCTCCAGGAT GACTTTGATT TCAACTATAA AACCCTCAAG
AGTCAAGGAG ACATGCAAGA TCTGAATGGA AACAACCAGT CAGTGACCAG GCAGAAGATG
CAGCAGCTGG AACAGATGCT CACTGCGCTG GACCAGATGC GGAGAAGCAT CGTGAGTGAG
CTGGCGGGGC TTTTGTCAGC GATGGAGTAC GTGCAGAAAA CTCTCACGGA CGAGGAGCTG
GCTGACTGGA AGAGGCGGCA ACAGATTGCC TGCATTGGAG GCCCGCCCAA CATCTGCCTA
GATCGGCTAG AAAACTGGAT AACGTCATTA GCAGAATCTC AACTTCAGAC CCGTCAACAA
ATTAAGAAAC TGGAGGAGTT GCAGCAAAAA GTTTCCTACA AAGGGGACCC CATTGTACAG
CACCGGCCGA TGCTGGAGGA GAGAATCGTG GAGCTGTTTA GAAACTTAAT GAAAAGTGCC
TTTGTGGTGG AGCGGCAGCC CTGCATGCCC ATGCATCCTG ACCGGCCCCT CGTCATCAAG
ACCGGCGTCC AGTTCACTAC TAAAGTCAGG TTGCTGGTCA AATTCCCTGA GTTGAATTAT
CAGCTTAAAA TTAAAGTGTG CATTGACAAA GACTCTGGGG ACGTTGCAGC TCTCAGAGGA
TCCCGGAAAT TTAACATTCT GGGCACAAAC ACAAAAGTGA TGAACATGGA AGAATCCAAC
AACGGCAGCC TCTCTGCAGA ATTCAAACAC TTGACCCTGA GGGAGCAGAG ATGTGGGAAT
GGGGGCCGAG CCAATTGTGA TGCTTCCCTG ATTGTGACTG AGGAGCTGCA CCTGATCACC
TTTGAGACCG AGGTGTATCA CCAAGGCCTC AAGATTGACC TAGAGACCCA CTCCTTGCCA
GTTGTGGTGA TCTCCAACAT CTGTCAGATG CCAAATGCCT GGGCGTCCAT CCTGTGGTAC
AACATGCTGA CCAACAATCC CAAGAATGTA AACTTTTTTA CCAAGCCCCC AATTGGAACC
TGGGATCAAG TGGCCGAGGT CCTGAGCTGG CAGTTCTCCT CCACCACCAA GCGAGGACTG
AGCATCGAGC AGCTGACTAC ACTGGCAGAG AAACTCTTGG GACCTGGTGT GAATTATTCA
GGGTGTCAGA TCACATGGGC TAAATTTTGC AAAGAAAACA TGGCTGGCAA GGGCTTCTCC
TTCTGGGTCT GGCTGGACAA TATCATTGAC CTTGTGAAAA AGTACATCCT GGCCCTTTGG
AACGAAGGGT ACATCATGGG CTTTATCAGT AAGGAGCGGG AGCGGGCCAT CTTGAGCACT
AAGCCTCCAG GCACCTTCCT GCTAAGATTC AGTGAAAGCA GCAAAGAAGG AGGCGTCACT
TTCACTTGGG TGGAGAAGGA CATCAGCGGT AAGACCCAGA TCCAGTCCGT GGAACCATAC
ACAAAGCAGC AGCTGAACAA CATGTCATTT GCTGAAATCA TCATGGGCTA TAAGATCATG
GATGCTACCA ATATCCTGGT GTCTCCACTG GTCTATCTCT ATCCTGACAT TCCCAAGGAG
GAGGCATTCG GAAAGTATTG TCGGCCAGAG AGCCAGGAGC ATCCTGAAGC TGACCCAGGT
AGCGCTGCCC CATACCTGAA GACCAAGTTT ATCTGTGTGA CACCAACGAC CTGCAGCAAT
ACCATTGACC TGCCGATGTC CCCCCGCACT TTAGATTCAT TGATGCAGTT TGGAAATAAT
GGTGAAGGTG CTGAACCCTC AGCAGGAGGG CAGTTTGAGT CCCTCACCTT TGACATGGAG
TTGACCTCGG AGTGCGCTAC CTCCCCCATG TGA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_644805.1
CDS241..2553
Misc Feature(1)148..150(+)
Misc Feature(2)218..240(+)
Misc Feature(3)244..600(+)
Misc Feature(4)244..246(+)
Misc Feature(5)655..1197(+)
Misc Feature(6)688..726(+)
Misc Feature(7)1201..1962(+)
Misc Feature(8)1900..2385(+)
Misc Feature(9)2011..2154(+)
Misc Feature(10)2149..2199(+)
Misc Feature(11)2179..2370(+)
Misc Feature(12)2209..2211(+)
Misc Feature(13)2260..2262(+)
Misc Feature(14)2293..2295(+)
Misc Feature(15)2293..2295(+)
Misc Feature(16)2311..2313(+)
Misc Feature(17)2353..2355(+)
Misc Feature(18)2353..2355(+)
Misc Feature(19)2353..2355(+)
Misc Feature(20)2353..2355(+)
Misc Feature(21)2353..2355(+)
Misc Feature(22)2353..2355(+)
Misc Feature(23)2353..2355(+)
Misc Feature(24)2353..2355(+)
Misc Feature(25)2353..2355(+)
Misc Feature(26)2419..2421(+)
Misc Feature(27)2419..2421(+)
Misc Feature(28)2419..2421(+)
Misc Feature(29)2419..2421(+)
Misc Feature(30)2419..2421(+)
Misc Feature(31)2419..2421(+)
Misc Feature(32)2419..2421(+)
Exon (1)1..217
Gene:STAT3
Gene Synonym:
Exon (2)218..368
Gene:STAT3
Gene Synonym:
Exon (3)369..513
Gene:STAT3
Gene Synonym:
Exon (4)514..612
Gene:STAT3
Gene Synonym:
Exon (5)613..708
Gene:STAT3
Gene Synonym:
Exon (6)709..790
Gene:STAT3
Gene Synonym:
Exon (7)791..885
Gene:STAT3
Gene Synonym:
Exon (8)886..1037
Gene:STAT3
Gene Synonym:
Exon (9)1038..1196
Gene:STAT3
Gene Synonym:
Exon (10)1197..1289
Gene:STAT3
Gene Synonym:
Exon (11)1290..1349
Gene:STAT3
Gene Synonym:
Exon (12)1350..1379
Gene:STAT3
Gene Synonym:
Exon (13)1380..1473
Gene:STAT3
Gene Synonym:
Exon (14)1474..1521
Gene:STAT3
Gene Synonym:
Exon (15)1522..1605
Gene:STAT3
Gene Synonym:
Exon (16)1606..1704
Gene:STAT3
Gene Synonym:
Exon (17)1705..1840
Gene:STAT3
Gene Synonym:
Exon (18)1841..1893
Gene:STAT3
Gene Synonym:
Exon (19)1894..1988
Gene:STAT3
Gene Synonym:
Exon (20)1989..2128
Gene:STAT3
Gene Synonym:
Exon (21)2129..2341
Gene:STAT3
Gene Synonym:
Exon (22)2342..2384
Gene:STAT3
Gene Synonym:
Exon (23)2385..2497
Gene:STAT3
Gene Synonym:
Exon (24)2498..4973
Gene:STAT3
Gene Synonym:
Translation
Position Chain Variation Link
6 6 c, g dbSNP:765882801
34 34 c, g dbSNP:566151688
37 37 c, g dbSNP:547925260
46 46 c, g dbSNP:780393027
76 76 c, t dbSNP:760179821
101 101 c, t dbSNP:528219097
102 102 a, g dbSNP:17883843
218 218 g, t dbSNP:768635673
235 235 a, g dbSNP:749109376
238 238 a, g dbSNP:779793392
240 240 c, g dbSNP:756099567
249 249 a, g dbSNP:749859511
278 278 a, g dbSNP:780720013
288 288 a, g dbSNP:563996007
303 303 c, g dbSNP:541045758
310 310 a, g dbSNP:751281347
312 312 c, t dbSNP:763742034
334 334 a, c dbSNP:1803125
339 339 c, t dbSNP:758631901
343 343 g, t dbSNP:748204289
375 375 a, c, t dbSNP:766994331
378 378 a, g dbSNP:760775429
383 383 a, g, t dbSNP:766875947
387 387 a, g dbSNP:767594035
399 399 c, t dbSNP:762135443
434 434 a, g dbSNP:775122881
436 436 c, g dbSNP:375760579
453 453 c, t dbSNP:530451908
465 465 a, g dbSNP:146184566
485 485 a, g dbSNP:776494537
487 487 c, t dbSNP:770878694
493 493 a, c dbSNP:746486285
543 543 c, t dbSNP:747612981
549 549 a, c, g dbSNP:17880940
560 560 a, g dbSNP:749626783
563 563 a, g dbSNP:780604324
567 567 g, t dbSNP:759676110
573 573 a, g dbSNP:750994809
576 576 a, g dbSNP:200440712
588 588 a, g dbSNP:200960081
592 592 a, t dbSNP:757305223
601 601 a, t dbSNP:751614036
603 603 a, t dbSNP:764338385
605 605 c, t dbSNP:774724351
613 613 c, g dbSNP:574370336
615 615 a, g dbSNP:747081170
617 617 a, g dbSNP:777883261
621 621 c, t dbSNP:758609919
645 645 c, t dbSNP:201846078
654 654 a, g dbSNP:765452694
660 660 a, g dbSNP:755877110
666 666 a, g dbSNP:774823374
669 669 a, g dbSNP:17878478
670 670 c, t dbSNP:761693018
675 675 a, g dbSNP:773889504
688 688 -, g dbSNP:35332755
753 753 c, t dbSNP:777828006
763 763 a, c dbSNP:758408552
775 775 c, t dbSNP:748237742
777 777 c, t dbSNP:779055365
791 791 a, g dbSNP:748184550
792 792 c, t dbSNP:202126764
798 798 a, g dbSNP:768898076
802 802 a, c dbSNP:749529243
807 807 a, t dbSNP:781034418
810 810 a, t dbSNP:756935531
827 827 a, c dbSNP:751411956
834 834 c, g dbSNP:374063766
861 861 c, t dbSNP:758449863
864 864 c, t dbSNP:752235250
867 867 a, c, g dbSNP:759225787
883 883 a, g dbSNP:753370239
891 891 c, t dbSNP:377095381
896 896 a, g dbSNP:762301765
900 900 a, g dbSNP:774652472
905 905 c, t dbSNP:764674735
906 906 a, g dbSNP:762891098
921 921 a, g dbSNP:775680553
927 927 a, g dbSNP:769885072
930 930 c, t dbSNP:746151758
933 933 g, t dbSNP:374524373
946 946 a, t dbSNP:773138024
947 947 c, g dbSNP:371541785
949 949 a, g dbSNP:376677265
951 951 c, t dbSNP:17882069
958 958 c, t dbSNP:754971639
963 963 a, c, t dbSNP:139588729
966 966 a, c dbSNP:755746762
979 979 c, t dbSNP:750141391
983 983 a, c dbSNP:757347742
986 986 c, t dbSNP:767159289
1005 1005 a, g dbSNP:527634708
1018 1018 c, g, t dbSNP:764478072
1030 1030 a, g dbSNP:763564047
1035 1035 a, c dbSNP:775421377
1039 1039 a, g dbSNP:749302989
1043 1043 a, c dbSNP:779422770
1044 1044 a, g dbSNP:755554248
1057 1057 c, t dbSNP:745393806
1062 1062 a, g dbSNP:780773507
1065 1065 g, t dbSNP:200098006
1074 1074 c, t dbSNP:751849047
1104 1104 c, g dbSNP:1064110
1119 1119 c, t dbSNP:147186377
1149 1149 a, g dbSNP:764577805
1153 1153 c, t dbSNP:758828674
1164 1164 a, g dbSNP:1064111
1167 1167 c, t dbSNP:779733888
1168 1168 a, g dbSNP:765856200
1179 1179 c, t dbSNP:1141111
1219 1219 c, g dbSNP:759527569
1243 1243 c, t dbSNP:193922716
1244 1244 a, g dbSNP:776115471
1251 1251 c, t dbSNP:200623682
1252 1252 a, g dbSNP:371953916
1263 1263 c, t dbSNP:777436789
1266 1266 c, t dbSNP:539947939
1279 1279 a, g dbSNP:748496600
1285 1285 a, g dbSNP:368454926
1287 1287 c, t dbSNP:779464807
1289 1289 g, t dbSNP:755524497
1290 1290 a, g dbSNP:771738153
1293 1293 a, g dbSNP:201472943
1299 1299 c, t dbSNP:774847480
1302 1302 a, g dbSNP:1141112
1313 1313 g, t dbSNP:769072802
1356 1356 c, t dbSNP:770311773
1362 1362 c, t dbSNP:376080249
1363 1363 a, g dbSNP:781724933
1367 1367 c, t dbSNP:373083464
1383 1383 c, g dbSNP:143571879
1384 1384 c, t dbSNP:113994135
1385 1385 a, g, t dbSNP:113994136
1406 1406 c, t dbSNP:397514766
1409 1409 a, g dbSNP:566350932
1415 1415 a, g dbSNP:587777648
1440 1440 c, t dbSNP:757298594
1443 1443 c, t dbSNP:189708970
1444 1444 a, g dbSNP:763754846
1455 1455 c, t dbSNP:769971732
1470 1470 c, t dbSNP:138001349
1477 1477 c, t dbSNP:146946014
1483 1483 a, g dbSNP:193922717
1485 1485 a, g dbSNP:184867029
1503 1503 a, g dbSNP:141151719
1508 1508 a, g dbSNP:113994137
1511 1511 c, t dbSNP:768739455
1520 1520 a, g dbSNP:749583802
1524 1524 c, t dbSNP:775806195
1560 1560 c, g dbSNP:770170991
1569 1569 a, c, t dbSNP:147955721
1571 1571 a, c dbSNP:771888821
1572 1572 a, g dbSNP:748180243
1584 1584 a, g dbSNP:778716670
1587 1587 c, t dbSNP:1141115
1591 1591 a, c dbSNP:768150168
1601 1601 c, t dbSNP:748564923
1603 1603 g, t dbSNP:34460718
1608 1608 a, c, t dbSNP:769425072
1618 1618 c, t dbSNP:1141116
1621 1621 c, g dbSNP:149214040
1627 1627 -, gtg dbSNP:113994138
1665 1665 a, g dbSNP:780713214
1668 1668 c, t dbSNP:369714894
1695 1695 a, c dbSNP:751900728
1699 1699 c, t dbSNP:199996352
1710 1710 a, g dbSNP:1141117
1716 1716 c, t dbSNP:1141118
1719 1719 c, t dbSNP:1141119
1722 1722 c, t dbSNP:1141120
1728 1728 c, g, t dbSNP:1141121
1732 1732 a, g dbSNP:146620441
1746 1746 c, t dbSNP:1064112
1749 1749 a, c dbSNP:763944667
1755 1755 c, t dbSNP:762743967
1759 1759 g, t dbSNP:145786768
1761 1761 c, g