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STAT4 signal transducer and activator of transcription 4 [Homo sapiens (human)]

Gene Symbol STAT4
Entrez Gene ID 6775
Full Name signal transducer and activator of transcription 4
Synonyms SLEB11
General protein information
Preferred Names
signal transducer and activator of transcription 4
Names
signal transducer and activator of transcription 4
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

2

2q32.2-q32.3

Summary The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Aug 2011]. lac of sum
Disorder MIM:

600558

Disorder Html: {Rheumatoid arthritis, association with}, 180300 (3); {Systemic





The following STAT4 gene sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the STAT4 gene which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu36570 XM_005246817 PREDICTED: Homo sapiens signal transducer and activator of transcription 4 (STAT4), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 12-14 Quote Price
OHu36570 XM_011511704 PREDICTED: Homo sapiens signal transducer and activator of transcription 4 (STAT4), transcript variant X2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 12-14 Quote Price
OHu18290 XM_011511705 PREDICTED: Homo sapiens signal transducer and activator of transcription 4 (STAT4), transcript variant X3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$559
OHu18290 XM_006712719 PREDICTED: Homo sapiens signal transducer and activator of transcription 4 (STAT4), transcript variant X4, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$559
OHu60771 XM_011511706 PREDICTED: Homo sapiens signal transducer and activator of transcription 4 (STAT4), transcript variant X5, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $439
OHu18290 NM_001243835 Homo sapiens signal transducer and activator of transcription 4 (STAT4), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$559
OHu18290 NM_003151 Homo sapiens signal transducer and activator of transcription 4 (STAT4), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$759

*Business Day
**You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.


CloneID OHu36570
Accession Version XM_005246817.3
Sequence Information ORF Nucleotide Sequence (Length: 2274bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product signal transducer and activator of transcription 4 isoform X2
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_005403.18) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 12, 2015 this sequence version replaced gi:578804822. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
ATGAAGTGGG GCAGCTATTT GTCCATCATG TCTCAGTGGA ATCAAGTCCA ACAGTTAGAA 
ATCAAGTTTT TGGAGCAGGT GGATCAATTC TATGATGACA ACTTTCCCAT GGAAATTCGG
CATCTGTTGG CCCAATGGAT TGAAAATCAA GACTGGGAGG CAGCTTCTAA CAATGAAACC
ATGGCAACGA TTCTTCTTCA AAACTTGTTA ATACAACTGG ATGAACAGTT AGGTCGTGTT
TCCAAAGAGA AAAACCTACT CTTGATACAC AATCTAAAAA GAATTAGGAA GGTCCTTCAG
GGAAAATTTC ATGGAAATCC AATGCATGTA GCTGTGGTTA TTTCAAACTG TTTAAGGGAA
GAGAGGAGAA TATTGGCTGC AGCCAACATG CCTGTCCAGG GGCCTCTAGA GAAATCCTTA
CAAAGTTCTT CAGTTTCAGA AAGACAGAGG AATGTGGAGC ACAAAGTGGC TGCCATTAAA
AACAGTGTGC AGATGACAGA ACAAGATACC AAATACTTAG AAGATCTGCA AGACGAATTT
GACTACAGGT ATAAAACAAT TCAGACAATG GATCAGAGTG ACAAGAATAG TGCCATGGTG
AATCAGGAAG TTTTGACACT GCAGGAAATG CTTAACAGCC TCGATTTCAA GAGAAAGGAG
GCTCTCAGTA AAATGACCCA AATCATCCAT GAGACAGACC TGTTAATGAA CACCATGCTC
ATAGAAGAGC TGCAAGACTG GAAGCGGCGG CAGCAAATCG CCTGCATCGG GGGTCCACTC
CACAATGGGC TCGACCAGCT TCAGAACTGC TTTACACTAT TGGCAGAAAG TCTTTTCCAA
CTGAGAAGGC AATTGGAGAA ACTAGAGGAG CAATCTACCA AAATGACATA TGAAGGTGAT
CCCATTCCAA TGCAAAGAAC TCACATGCTA GAAAGAGTCA CCTTCTTGAT CTACAACCTT
TTCAAGAACT CATTTGTGGT TGAGCGACAG CCATGTATGC CAACCCACCC TCAGAGGCCG
TTGGTACTTA AAACCCTAAT TCAGTTCACT GTAAAACTAA GGCTACTAAT AAAATTGCCA
GAACTAAACT ATCAGGTAAA GGTTAAGGCA TCAATTGACA AGAATGTTTC AACTCTAAGC
AACCGAAGAT TTGTACTTTG TGGAACTAAT GTCAAAGCCA TGTCTATTGA AGAATCTTCC
AATGGGAGTC TCTCAGTAGA ATTTCGACAT TTGCAACCAA AGGAAATGAA GTCCAGTGCT
GGAGGTAAAG GAAATGAGGG CTGTCACATG GTGACTGAAG AACTTCATTC CATAACGTTT
GAAACACAGA TCTGCCTCTA TGGCCTGACC ATAGATTTGG AGACCAGCTC ATTGCCTGTG
GTGATGATTT CCAATGTCAG TCAGTTACCT AATGCTTGGG CATCCATCAT TTGGTACAAC
GTGTCAACCA ACGATTCCCA GAACTTGGTT TTCTTTAATA ATCCTCCACC TGCCACATTG
AGTCAACTAC TGGAGGTGAT GAGCTGGCAG TTTTCATCGT ACGTTGGTCG TGGTCTTAAC
TCAGATCAAC TCCATATGCT GGCAGAGAAG CTTACAGTCC AATCTAGCTA CAGTGATGGT
CACCTCACCT GGGCCAAGTT CTGCAAGGAA CATTTACCTG GTAAATCATT TACCTTTTGG
ACATGGCTTG AAGCAATATT GGATCTAATT AAGAAACACA TTCTTCCCCT TTGGATTGAT
GGGTATGTCA TGGGCTTTGT TAGCAAAGAG AAGGAACGGC TGTTGCTAAA GGATAAAATG
CCTGGCACCT TTTTATTAAG ATTCAGTGAA AGCCATCTCG GAGGAATAAC TTTCACCTGG
GTGGACCATT CTGAAAGTGG GGAAGTGAGA TTCCACTCTG TAGAACCCTA CAATAAAGGC
CGGTTGTCTG CTCTGCCATT CGCTGACATC CTGCGAGACT ACAAAGTTAT TATGGCTGAA
AACATTCCTG AAAACCCTCT GAAGTACCTA TATCCTGACA TTCCCAAAGA CAAAGCCTTC
GGTAAACACT ACAGCTCTCA GCCTTGCGAA GTTTCAAGAC CAACAGAAAG GGGTGACAAA
GGTTATGTTC CTTCTGTTTT TATCCCCATC TCAACAATCC GAAGTGATTC AACAGAGCCA
CATTCTCCAT CAGACCTTCT TCCCATGTCT CCAAGTGTGT ATGCGGTGTT GAGAGAAAAC
CTGAGTCCCA CAACAATTGA AACTGCAATG AAGTCTCCTT ATTCTGCTGA ATGA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqXP_005246874.1
CDS153..2426
Misc Feature(1)183..542(+)
Misc Feature(2)588..1121(+)
Misc Feature(3)1125..1868(+)
Misc Feature(4)1836..2279(+)
Misc Feature(5)1917..2057(+)
Misc Feature(6)2052..2102(+)
Misc Feature(7)2082..2273(+)
Translation
Position Chain Variation Link
4 4 a, g dbSNP:561968001
25 25 a, g dbSNP:376440088
52 52 c, t dbSNP:116702348
63 63 a, c dbSNP:6434450
76 76 a, g dbSNP:370842370
84 84 a, g dbSNP:539897798
126 126 a, g dbSNP:541906168
135 135 a, g dbSNP:574621309
199 199 c, t dbSNP:778760914
215 215 a, c dbSNP:754787268
221 221 c, t dbSNP:753587179
275 275 g, t dbSNP:766134008
284 284 a, c dbSNP:760427388
287 287 a, g dbSNP:750034868
293 293 c, t dbSNP:35500382
304 304 a, g dbSNP:761161672
314 314 a, g dbSNP:756950986
340 340 c, t dbSNP:750095435
362 362 a, g dbSNP:767019947
381 381 -, ttag dbSNP:766324016
386 386 a, t dbSNP:369256225
388 388 g, t dbSNP:751076320
394 394 c, t dbSNP:267599129
396 396 a, g dbSNP:763673195
414 414 c, t dbSNP:760176547
424 424 a, g dbSNP:777271668
428 428 a, g dbSNP:546810787
439 439 a, g dbSNP:202184860
451 451 a, g dbSNP:773503051
462 462 c, t dbSNP:757999757
474 474 a, g dbSNP:752105122
481 481 c, t dbSNP:778453112
489 489 a, g dbSNP:756625612
497 497 a, g dbSNP:3024838
503 503 c, t dbSNP:560856047
512 512 a, g dbSNP:762103216
522 522 a, g dbSNP:3024839
531 531 a, g dbSNP:372012413
537 537 a, g dbSNP:763055396
539 539 c, t dbSNP:775474969
553 553 a, g dbSNP:773188982
554 554 a, g dbSNP:771977877
562 562 a, t dbSNP:140675301
569 569 c, t dbSNP:145071895
570 570 c, t dbSNP:768064931
606 606 a, g, t dbSNP:370819441
611 611 a, g dbSNP:757804856
621 621 c, g dbSNP:747495835
625 625 c, t dbSNP:778170459
631 631 c, t dbSNP:551175992
639 639 a, g dbSNP:758720903
646 646 c, t dbSNP:376677137
648 648 a, g dbSNP:372399682
661 661 c, t dbSNP:775033600
668 668 -, ctta dbSNP:779446409
683 683 a, g dbSNP:35918099
686 686 c, t dbSNP:199940585
699 699 a, g dbSNP:778192508
708 708 a, g dbSNP:758709109
710 710 a, g dbSNP:748501058
722 722 c, g dbSNP:779115246
729 729 a, g dbSNP:757114207
738 738 a, t dbSNP:769304507
749 749 c, g dbSNP:543324204
782 782 a, g dbSNP:773619472
785 785 a, t dbSNP:74378111
791 791 a, c dbSNP:144713478
794 794 c, g dbSNP:753599408
809 809 a, g dbSNP:367890072
813 813 a, g dbSNP:757165202
819 819 a, g dbSNP:145218540
829 829 c, t dbSNP:778253892
833 833 a, g dbSNP:139598810
834 834 a, g dbSNP:749622712
841 841 a, g dbSNP:780454944
859 859 c, t dbSNP:770181391
869 869 a, g dbSNP:746059460
870 870 a, c dbSNP:781395541
872 872 c, t dbSNP:757282952
874 874 c, t dbSNP:746974489
875 875 a, g dbSNP:371181176
879 879 a, g dbSNP:758217844
898 898 a, g dbSNP:61756200
901 901 a, g dbSNP:764990697
911 911 c, t dbSNP:557179689
912 912 a, g, t dbSNP:201972198
913 913 c, t dbSNP:760044145
920 920 c, t dbSNP:189939340
921 921 a, g dbSNP:764656850
929 929 a, g dbSNP:763524392
934 934 a, g dbSNP:776049747
937 937 a, g dbSNP:770273474
941 941 c, g dbSNP:746170953
944 944 c, t dbSNP:138111228
945 945 a, g dbSNP:771061948
957 957 a, g dbSNP:113436186
959 959 c, t dbSNP:747018092
971 971 a, c dbSNP:776940641
973 973 c, t dbSNP:779542390
984 984 a, c dbSNP:35279173
986 986 c, t dbSNP:747228179
992 992 a, g, t dbSNP:571829920
995 995 a, g dbSNP:140221173
996 996 a, g dbSNP:748082505
997 997 a, g dbSNP:778762924
1004 1004 a, g dbSNP:768517793
1013 1013 a, g dbSNP:748998598
1017 1017 a, g dbSNP:142125913
1019 1019 a, g dbSNP:532043947
1025 1025 a, g dbSNP:755772067
1030 1030 c, t dbSNP:750090759
1037 1037 c, g dbSNP:780920887
1043 1043 c, t dbSNP:138535661
1055 1055 c, t dbSNP:374707313
1060 1060 c, t dbSNP:765796756
1063 1063 a, t dbSNP:760055169
1068 1068 a, g dbSNP:754199351
1072 1072 c, t dbSNP:200982266
1098 1098 c, t dbSNP:760872742
1100 1100 c, g dbSNP:548245892
1101 1101 a, g dbSNP:772150342
1102 1102 g, t dbSNP:761830960
1109 1109 c, t dbSNP:140970138
1110 1110 c, g, t dbSNP:749227253
1113 1113 g, t dbSNP:779772586
1133 1133 a, t dbSNP:774465481
1138 1138 a, g dbSNP:143642103
1145 1145 a, g dbSNP:762868543
1149 1149 a, g dbSNP:775435376
1151 1151 a, g dbSNP:769491603
1160 1160 c, t dbSNP:745613218
1172 1172 a, g dbSNP:559315611
1185 1185 a, t dbSNP:770753645
1200 1200 a, t dbSNP:746642521
1204 1204 c, t dbSNP:777211622
1209 1209 c, g dbSNP:757857474
1232 1232 a, c dbSNP:181250926
1248 1248 a, g dbSNP:757553644
1260 1260 a, g dbSNP:751746803
1267 1267 c, t dbSNP:764332457
1278 1278 c, g dbSNP:777972042
1296 1296 c, t dbSNP:768169551
1304 1304 -, t dbSNP:763732068
1304 1304 a, t dbSNP:750700455
1306 1306 c, t dbSNP:762403752
1316 1316 a, t dbSNP:777158012
1324 1324 c, t dbSNP:771471597
1334 1334 a, g dbSNP:376043190
1338 1338 a, g dbSNP:368876096
1357 1357 c, g dbSNP:199633613
1373 1373 a, g dbSNP:772256750
1387 1387 a, t dbSNP:775033790
1389 1389 c, t dbSNP:764645584
1390 1390 c, t dbSNP:200636478
1409 1409 c, t dbSNP:773531490
1417 1417 c, g dbSNP:772506095
1463 1463 c, t dbSNP:201192423
1465 1465 c, t dbSNP:763858532
1468 1468 c, t dbSNP:758109437
1469 1469 a, g dbSNP:145312304
1503 1503 a, g dbSNP:764815073
1516 1516 c, t dbSNP:141331848
1517 1517 a, c dbSNP:144421302
1520 1520 a, c dbSNP:530278225
1527 1527 c, g dbSNP:544508292
1547 1547 c, t dbSNP:778632183
1571 1571 a, g dbSNP:762476453
1577 1577 c, t dbSNP:200929981
1592 1592 c, t dbSNP:142491497
1603 1603 a, g, t dbSNP:146386562
1604 1604 c, t dbSNP:769952683
1605 1605 a, g dbSNP:759785386
1614 1614 a, c dbSNP:765625619
1616 1616 c, t dbSNP:138956189
1620 1620 a, g dbSNP:769270663
1633 1633 a, c dbSNP:771017653
1634 1634 c, t dbSNP:760702751
1637 1637 c, t dbSNP:79347691
1640 1640 a, c dbSNP:77509921
1650 1650 c, t dbSNP:373669618
1652 1652 g, t dbSNP:149621054
1655 1655 c, t dbSNP:138191914
1662 1662 c, t dbSNP:748906866
1691 1691 a, g dbSNP:201470036
1694 1694 c, t dbSNP:139085875
1695 1695 a, g dbSNP:749994944
1701 1701 c, t dbSNP:780829180
1702 1702 a, g dbSNP:376947712
1717 1717 a, t dbSNP:147007636
1728 1728 a, g, t dbSNP:755317297
1763 1763 c, t dbSNP:768445696
1765 1765 a, g dbSNP:760335389
1775 1775 c, t dbSNP:147850919
1776 1776 c, t dbSNP:767596903
1785 1785 a, g dbSNP:761904937
1795 1795 a, g dbSNP:774187563
1803 1803 c, t dbSNP:765178000
1819 1819 c, t dbSNP:144091208
1820 1820 a, g dbSNP:759378650
1827 1827 c, t dbSNP:373191999
1831 1831 a, g dbSNP:776531286
1874 1874 c, t dbSNP:770642587
1876 1876 g, t dbSNP:760189410
1880 1880 c, t dbSNP:540628434
1907 1907 c, t dbSNP:760443863
1929 1929 c, t dbSNP:3024933
1930 1930 a, g, t dbSNP:779069171
1935 1935 g, t dbSNP:199609035
1952 1952 a, g dbSNP:761281261
1953 1953 c, g dbSNP:773810325
1969 1969 c, t dbSNP:770306554
1985 1985 c, g dbSNP:201150110
1991 1991 c, t dbSNP:781621586
1992 1992 a, g dbSNP:771192197
1994 1994 a, g dbSNP:747310117
2029 2029 c, g dbSNP:777832373
2032 2032 c, g dbSNP:776987023
2040 2040 a, c dbSNP:771372502
2060 2060 c, g dbSNP:747300394
2074 2074 a, g dbSNP:149089413
2075 2075 g, t dbSNP:112819248
2093 2093 a, c, t dbSNP:369720896
2094 2094 g, t dbSNP:755096256
2106 2106 a, c dbSNP:759048381
2138 2138 g, t dbSNP:749296968
2141 2141 c, t dbSNP:779825681
2149 2149 c, t dbSNP:756037985
2150 2150 a, t dbSNP:750206397
2151 2151 c, t dbSNP:202018151
2162 2162 a, g dbSNP:767240927
2174 2174 c, t dbSNP:756905537
2182 2182 a, g dbSNP:751205891
2192 2192 c, t dbSNP:368134591
2193 2193 a, g dbSNP:762343259
2197 2197 a, g dbSNP:777230968
2208 2208 a, t dbSNP:766821566
2209 2209 c, g dbSNP:761189841
2219 2219 a, c, t dbSNP:368928990
2237 2237 a, c dbSNP:764742090
2241 2241 a, g dbSNP:761155615
2242 2242 a, g dbSNP:371989874
2243 2243 c, g dbSNP:768045385
2248 2248 a, c, g dbSNP:774816816
2267 2267 c, t dbSNP:550869545
2268 2268 g, t dbSNP:768782205
2279 2279 a, c dbSNP:763177887
2288 2288 a, t dbSNP:775435740
2293 2293 a, g dbSNP:370218298
2299 2299 a, g dbSNP:111535990
2304 2304 a, g dbSNP:770874469
2305 2305 a, c dbSNP:746885035
2313 2313 c, t dbSNP:772952207
2314 2314 a, g dbSNP:752431273
2345 2345 a, c dbSNP:781093912
2356 2356 c, t dbSNP:771889653
2357 2357 a, c, g dbSNP:139030621
2372 2372 c, t dbSNP:754637298
2381 2381 a, c dbSNP:748831456
2386 2386 -, caa dbSNP:776683947
2387 2387 a, g dbSNP:779652985
2396 2396 g, t dbSNP:757844095
2410 2410 c, g dbSNP:773968889
2419 2419 c, t dbSNP:768437698
2432 2432 c, t dbSNP:748882692
2434 2434 a, c dbSNP:3024906
2439 2439 c, t dbSNP:373725872
2442 2442 c, t dbSNP:199549890
2443 2443 a, c, g dbSNP:376543078
2444 2444 c, t dbSNP:758789071
2446 2446 c, t dbSNP:373617359
2448 2448 a, g dbSNP:765524533
2455 2455 c, g dbSNP:755264465
2462 2462 a, g dbSNP:778533196
2465 2465 a, g dbSNP:370883796
2471 2471 g, t dbSNP:766497133
2472 2472 g, t dbSNP:527418737
2473 2473 c, t dbSNP:750431303
2506 2506 a, g dbSNP:775951674
2515 2515 a, g dbSNP:191594904
2550 2550 a, g dbSNP:3024907
2587 2587 a, g dbSNP:148090220
2588 2588 c, t dbSNP:113109887
2598 2598 c, t dbSNP:574975927
2634 2634 a, t dbSNP:2280236
2643 2643 a, c dbSNP:770091061
2672 2672 c, t dbSNP:753311752

Target ORF information:

RefSeq Version XM_005246817
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens signal transducer and activator of transcription 4 (STAT4), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_005246817

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
ATGAAGTGGG GCAGCTATTT GTCCATCATG TCTCAGTGGA ATCAAGTCCA ACAGTTAGAA 
ATCAAGTTTT TGGAGCAGGT GGATCAATTC TATGATGACA ACTTTCCCAT GGAAATTCGG
CATCTGTTGG CCCAATGGAT TGAAAATCAA GACTGGGAGG CAGCTTCTAA CAATGAAACC
ATGGCAACGA TTCTTCTTCA AAACTTGTTA ATACAACTGG ATGAACAGTT AGGTCGTGTT
TCCAAAGAGA AAAACCTACT CTTGATACAC AATCTAAAAA GAATTAGGAA GGTCCTTCAG
GGAAAATTTC ATGGAAATCC AATGCATGTA GCTGTGGTTA TTTCAAACTG TTTAAGGGAA
GAGAGGAGAA TATTGGCTGC AGCCAACATG CCTGTCCAGG GGCCTCTAGA GAAATCCTTA
CAAAGTTCTT CAGTTTCAGA AAGACAGAGG AATGTGGAGC ACAAAGTGGC TGCCATTAAA
AACAGTGTGC AGATGACAGA ACAAGATACC AAATACTTAG AAGATCTGCA AGACGAATTT
GACTACAGGT ATAAAACAAT TCAGACAATG GATCAGAGTG ACAAGAATAG TGCCATGGTG
AATCAGGAAG TTTTGACACT GCAGGAAATG CTTAACAGCC TCGATTTCAA GAGAAAGGAG
GCTCTCAGTA AAATGACCCA AATCATCCAT GAGACAGACC TGTTAATGAA CACCATGCTC
ATAGAAGAGC TGCAAGACTG GAAGCGGCGG CAGCAAATCG CCTGCATCGG GGGTCCACTC
CACAATGGGC TCGACCAGCT TCAGAACTGC TTTACACTAT TGGCAGAAAG TCTTTTCCAA
CTGAGAAGGC AATTGGAGAA ACTAGAGGAG CAATCTACCA AAATGACATA TGAAGGTGAT
CCCATTCCAA TGCAAAGAAC TCACATGCTA GAAAGAGTCA CCTTCTTGAT CTACAACCTT
TTCAAGAACT CATTTGTGGT TGAGCGACAG CCATGTATGC CAACCCACCC TCAGAGGCCG
TTGGTACTTA AAACCCTAAT TCAGTTCACT GTAAAACTAA GGCTACTAAT AAAATTGCCA
GAACTAAACT ATCAGGTAAA GGTTAAGGCA TCAATTGACA AGAATGTTTC AACTCTAAGC
AACCGAAGAT TTGTACTTTG TGGAACTAAT GTCAAAGCCA TGTCTATTGA AGAATCTTCC
AATGGGAGTC TCTCAGTAGA ATTTCGACAT TTGCAACCAA AGGAAATGAA GTCCAGTGCT
GGAGGTAAAG GAAATGAGGG CTGTCACATG GTGACTGAAG AACTTCATTC CATAACGTTT
GAAACACAGA TCTGCCTCTA TGGCCTGACC ATAGATTTGG AGACCAGCTC ATTGCCTGTG
GTGATGATTT CCAATGTCAG TCAGTTACCT AATGCTTGGG CATCCATCAT TTGGTACAAC
GTGTCAACCA ACGATTCCCA GAACTTGGTT TTCTTTAATA ATCCTCCACC TGCCACATTG
AGTCAACTAC TGGAGGTGAT GAGCTGGCAG TTTTCATCGT ACGTTGGTCG TGGTCTTAAC
TCAGATCAAC TCCATATGCT GGCAGAGAAG CTTACAGTCC AATCTAGCTA CAGTGATGGT
CACCTCACCT GGGCCAAGTT CTGCAAGGAA CATTTACCTG GTAAATCATT TACCTTTTGG
ACATGGCTTG AAGCAATATT GGATCTAATT AAGAAACACA TTCTTCCCCT TTGGATTGAT
GGGTATGTCA TGGGCTTTGT TAGCAAAGAG AAGGAACGGC TGTTGCTAAA GGATAAAATG
CCTGGCACCT TTTTATTAAG ATTCAGTGAA AGCCATCTCG GAGGAATAAC TTTCACCTGG
GTGGACCATT CTGAAAGTGG GGAAGTGAGA TTCCACTCTG TAGAACCCTA CAATAAAGGC
CGGTTGTCTG CTCTGCCATT CGCTGACATC CTGCGAGACT ACAAAGTTAT TATGGCTGAA
AACATTCCTG AAAACCCTCT GAAGTACCTA TATCCTGACA TTCCCAAAGA CAAAGCCTTC
GGTAAACACT ACAGCTCTCA GCCTTGCGAA GTTTCAAGAC CAACAGAAAG GGGTGACAAA
GGTTATGTTC CTTCTGTTTT TATCCCCATC TCAACAATCC GAAGTGATTC AACAGAGCCA
CATTCTCCAT CAGACCTTCT TCCCATGTCT CCAAGTGTGT ATGCGGTGTT GAGAGAAAAC
CTGAGTCCCA CAACAATTGA AACTGCAATG AAGTCTCCTT ATTCTGCTGA ATGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu36570
Accession Version XM_011511704.1
Sequence Information ORF Nucleotide Sequence (Length: 2274bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product signal transducer and activator of transcription 4 isoform X2
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_005403.18) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
ATGAAGTGGG GCAGCTATTT GTCCATCATG TCTCAGTGGA ATCAAGTCCA ACAGTTAGAA 
ATCAAGTTTT TGGAGCAGGT GGATCAATTC TATGATGACA ACTTTCCCAT GGAAATTCGG
CATCTGTTGG CCCAATGGAT TGAAAATCAA GACTGGGAGG CAGCTTCTAA CAATGAAACC
ATGGCAACGA TTCTTCTTCA AAACTTGTTA ATACAACTGG ATGAACAGTT AGGTCGTGTT
TCCAAAGAGA AAAACCTACT CTTGATACAC AATCTAAAAA GAATTAGGAA GGTCCTTCAG
GGAAAATTTC ATGGAAATCC AATGCATGTA GCTGTGGTTA TTTCAAACTG TTTAAGGGAA
GAGAGGAGAA TATTGGCTGC AGCCAACATG CCTGTCCAGG GGCCTCTAGA GAAATCCTTA
CAAAGTTCTT CAGTTTCAGA AAGACAGAGG AATGTGGAGC ACAAAGTGGC TGCCATTAAA
AACAGTGTGC AGATGACAGA ACAAGATACC AAATACTTAG AAGATCTGCA AGACGAATTT
GACTACAGGT ATAAAACAAT TCAGACAATG GATCAGAGTG ACAAGAATAG TGCCATGGTG
AATCAGGAAG TTTTGACACT GCAGGAAATG CTTAACAGCC TCGATTTCAA GAGAAAGGAG
GCTCTCAGTA AAATGACCCA AATCATCCAT GAGACAGACC TGTTAATGAA CACCATGCTC
ATAGAAGAGC TGCAAGACTG GAAGCGGCGG CAGCAAATCG CCTGCATCGG GGGTCCACTC
CACAATGGGC TCGACCAGCT TCAGAACTGC TTTACACTAT TGGCAGAAAG TCTTTTCCAA
CTGAGAAGGC AATTGGAGAA ACTAGAGGAG CAATCTACCA AAATGACATA TGAAGGTGAT
CCCATTCCAA TGCAAAGAAC TCACATGCTA GAAAGAGTCA CCTTCTTGAT CTACAACCTT
TTCAAGAACT CATTTGTGGT TGAGCGACAG CCATGTATGC CAACCCACCC TCAGAGGCCG
TTGGTACTTA AAACCCTAAT TCAGTTCACT GTAAAACTAA GGCTACTAAT AAAATTGCCA
GAACTAAACT ATCAGGTAAA GGTTAAGGCA TCAATTGACA AGAATGTTTC AACTCTAAGC
AACCGAAGAT TTGTACTTTG TGGAACTAAT GTCAAAGCCA TGTCTATTGA AGAATCTTCC
AATGGGAGTC TCTCAGTAGA ATTTCGACAT TTGCAACCAA AGGAAATGAA GTCCAGTGCT
GGAGGTAAAG GAAATGAGGG CTGTCACATG GTGACTGAAG AACTTCATTC CATAACGTTT
GAAACACAGA TCTGCCTCTA TGGCCTGACC ATAGATTTGG AGACCAGCTC ATTGCCTGTG
GTGATGATTT CCAATGTCAG TCAGTTACCT AATGCTTGGG CATCCATCAT TTGGTACAAC
GTGTCAACCA ACGATTCCCA GAACTTGGTT TTCTTTAATA ATCCTCCACC TGCCACATTG
AGTCAACTAC TGGAGGTGAT GAGCTGGCAG TTTTCATCGT ACGTTGGTCG TGGTCTTAAC
TCAGATCAAC TCCATATGCT GGCAGAGAAG CTTACAGTCC AATCTAGCTA CAGTGATGGT
CACCTCACCT GGGCCAAGTT CTGCAAGGAA CATTTACCTG GTAAATCATT TACCTTTTGG
ACATGGCTTG AAGCAATATT GGATCTAATT AAGAAACACA TTCTTCCCCT TTGGATTGAT
GGGTATGTCA TGGGCTTTGT TAGCAAAGAG AAGGAACGGC TGTTGCTAAA GGATAAAATG
CCTGGCACCT TTTTATTAAG ATTCAGTGAA AGCCATCTCG GAGGAATAAC TTTCACCTGG
GTGGACCATT CTGAAAGTGG GGAAGTGAGA TTCCACTCTG TAGAACCCTA CAATAAAGGC
CGGTTGTCTG CTCTGCCATT CGCTGACATC CTGCGAGACT ACAAAGTTAT TATGGCTGAA
AACATTCCTG AAAACCCTCT GAAGTACCTA TATCCTGACA TTCCCAAAGA CAAAGCCTTC
GGTAAACACT ACAGCTCTCA GCCTTGCGAA GTTTCAAGAC CAACAGAAAG GGGTGACAAA
GGTTATGTTC CTTCTGTTTT TATCCCCATC TCAACAATCC GAAGTGATTC AACAGAGCCA
CATTCTCCAT CAGACCTTCT TCCCATGTCT CCAAGTGTGT ATGCGGTGTT GAGAGAAAAC
CTGAGTCCCA CAACAATTGA AACTGCAATG AAGTCTCCTT ATTCTGCTGA ATGA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqXP_011510006.1
CDS2137..4410
Misc Feature(1)2167..2526(+)
Misc Feature(2)2572..3105(+)
Misc Feature(3)3109..3852(+)
Misc Feature(4)3820..4263(+)
Misc Feature(5)3901..4041(+)
Misc Feature(6)4036..4086(+)
Misc Feature(7)4066..4257(+)
Translation
Position Chain Variation Link
2 2 g, t dbSNP:369382384
9 9 a, g dbSNP:532870442
15 15 c, g dbSNP:770265662
27 27 a, t dbSNP:111417394
39 39 a, g dbSNP:112057280
54 54 c, g dbSNP:563911387
84 84 c, g dbSNP:374994140
103 103 g, t dbSNP:545799987
113 113 g, t dbSNP:574967051
114 114 c, t dbSNP:563047588
167 167 c, t dbSNP:541582472
178 178 a, g dbSNP:371519869
196 196 a, g dbSNP:73058613
266 266 a, c dbSNP:747569738
323 323 a, g dbSNP:565595427
376 376 g, t dbSNP:547468855
389 389 c, t dbSNP:532137555
392 392 a, t dbSNP:568248960
408 408 c, t dbSNP:565060379
446 446 a, g dbSNP:35092718
454 454 a, c dbSNP:765802335
460 460 c, g dbSNP:531609395
499 499 a, g dbSNP:750741645
501 501 a, g dbSNP:62179632
538 538 -, t dbSNP:781105605
555 555 a, g dbSNP:375793559
595 595 -, tatca dbSNP:751788437
595 595 c, t dbSNP:542616130
603 603 a, g dbSNP:140014077
614 614 c, t dbSNP:182198062
629 629 a, t dbSNP:371551159
653 653 a, g dbSNP:545461237
664 664 a, g dbSNP:764319836
677 677 a, t dbSNP:551944323
699 699 c, t dbSNP:775638791
702 702 c, t dbSNP:556303751
703 703 a, g dbSNP:527384504
739 739 g, t dbSNP:559083027
792 792 c, t dbSNP:10931490
881 881 a, g dbSNP:138623729
888 888 c, t dbSNP:1454755
912 912 a, g dbSNP:181776352
959 959 c, t dbSNP:748145089
986 986 a, g dbSNP:757079834
1005 1005 g, t dbSNP:190741152
1024 1024 a, g dbSNP:552402031
1029 1029 c, t dbSNP:550787825
1031 1031 c, t dbSNP:535741134
1037 1037 c, g dbSNP:527435290
1043 1043 a, c dbSNP:746845358
1065 1065 g, t dbSNP:560088335
1087 1087 c, g dbSNP:542269674
1112 1112 c, t dbSNP:568452907
1145 1145 c, t dbSNP:548527834
1190 1190 a, g, t dbSNP:527283753
1240 1240 a, g dbSNP:559962633
1241 1241 a, g dbSNP:574826737
1291 1291 g, t dbSNP:150619793
1309 1309 a, g dbSNP:764776288
1311 1311 a, g dbSNP:7595886
1323 1323 a, t dbSNP:562700415
1347 1347 c, t dbSNP:75885142
1351 1351 a, g dbSNP:573942864
1366 1366 a, g dbSNP:561968001
1387 1387 a, g dbSNP:376440088
1414 1414 c, t dbSNP:116702348
1425 1425 a, c dbSNP:6434450
1438 1438 a, g dbSNP:370842370
1446 1446 a, g dbSNP:539897798
1460 1460 a, g dbSNP:575654948
1469 1469 a, g dbSNP:188131520
1481 1481 a, g dbSNP:570784008
1506 1506 a, g dbSNP:778564542
1553 1553 c, g dbSNP:749404471
1561 1561 g, t dbSNP:141737184
1568 1568 a, g dbSNP:11893452
1575 1575 a, g dbSNP:554062970
1579 1579 c, t dbSNP:553186356
1589 1589 a, g dbSNP:78196109
1603 1603 c, t dbSNP:753399538
1604 1604 a, g dbSNP:777082929
1665 1665 a, g dbSNP:73980006
1681 1681 c, t dbSNP:557695026
1704 1704 c, t dbSNP:148256107
1759 1759 a, c dbSNP:143173669
1768 1768 c, t dbSNP:149542012
1812 1812 a, c dbSNP:13392229
1831 1831 a, g dbSNP:550709201
1838 1838 c, t dbSNP:755578097
1839 1839 a, g dbSNP:535686847
1844 1844 -, t dbSNP:397869656
1852 1852 -, t dbSNP:34316236
1853 1853 -, t dbSNP:574764548
1855 1855 a, g dbSNP:745834096
1858 1858 a, t dbSNP:73980005
1872 1872 a, t dbSNP:73980003
1884 1884 a, g dbSNP:755625489
1889 1889 c, t dbSNP:373803467
1890 1890 a, g dbSNP:7589450
1922 1922 c, t dbSNP:528380150
1927 1927 a, t dbSNP:766904114
1929 1929 a, g dbSNP:564234980
1950 1950 a, g dbSNP:546134565
1966 1966 a, g dbSNP:530147009
1977 1977 c, g dbSNP:570762403
1998 1998 a, g dbSNP:563408234
2059 2059 a, t dbSNP:559402424
2074 2074 c, g dbSNP:765581076
2110 2110 a, g dbSNP:541906168
2119 2119 a, g dbSNP:574621309
2183 2183 c, t dbSNP:778760914
2199 2199 a, c dbSNP:754787268
2205 2205 c, t dbSNP:753587179
2259 2259 g, t dbSNP:766134008
2268 2268 a, c dbSNP:760427388
2271 2271 a, g dbSNP:750034868
2277 2277 c, t dbSNP:35500382
2288 2288 a, g dbSNP:761161672
2298 2298 a, g dbSNP:756950986
2324 2324 c, t dbSNP:750095435
2346 2346 a, g dbSNP:767019947
2365 2365 -, ttag dbSNP:766324016
2370 2370 a, t dbSNP:369256225
2372 2372 g, t dbSNP:751076320
2378 2378 c, t dbSNP:267599129
2380 2380 a, g dbSNP:763673195
2398 2398 c, t dbSNP:760176547
2408 2408 a, g dbSNP:777271668
2412 2412 a, g dbSNP:546810787
2423 2423 a, g dbSNP:202184860
2435 2435 a, g dbSNP:773503051
2446 2446 c, t dbSNP:757999757
2458 2458 a, g dbSNP:752105122
2465 2465 c, t dbSNP:778453112
2473 2473 a, g dbSNP:756625612
2481 2481 a, g dbSNP:3024838
2487 2487 c, t dbSNP:560856047
2496 2496 a, g dbSNP:762103216
2506 2506 a, g dbSNP:3024839
2515 2515 a, g dbSNP:372012413
2521 2521 a, g dbSNP:763055396
2523 2523 c, t dbSNP:775474969
2537 2537 a, g dbSNP:773188982
2538 2538 a, g dbSNP:771977877
2546 2546 a, t dbSNP:140675301
2553 2553 c, t dbSNP:145071895
2554 2554 c, t dbSNP:768064931
2590 2590 a, g, t dbSNP:370819441
2595 2595 a, g dbSNP:757804856
2605 2605 c, g dbSNP:747495835
2609 2609 c, t dbSNP:778170459
2615 2615 c, t dbSNP:551175992
2623 2623 a, g dbSNP:758720903
2630 2630 c, t dbSNP:376677137
2632 2632 a, g dbSNP:372399682
2645 2645 c, t dbSNP:775033600
2652 2652 -, ctta dbSNP:779446409
2667 2667 a, g dbSNP:35918099
2670 2670 c, t dbSNP:199940585
2683 2683 a, g dbSNP:778192508
2692 2692 a, g dbSNP:758709109
2694 2694 a, g dbSNP:748501058
2706 2706 c, g dbSNP:779115246
2713 2713 a, g dbSNP:757114207
2722 2722 a, t dbSNP:769304507
2733 2733 c, g dbSNP:543324204
2766 2766 a, g dbSNP:773619472
2769 2769 a, t dbSNP:74378111
2775 2775 a, c dbSNP:144713478
2778 2778 c, g dbSNP:753599408
2793 2793 a, g dbSNP:367890072
2797 2797 a, g dbSNP:757165202
2803 2803 a, g dbSNP:145218540
2813 2813 c, t dbSNP:778253892
2817 2817 a, g dbSNP:139598810
2818 2818 a, g dbSNP:749622712
2825 2825 a, g dbSNP:780454944
2843 2843 c, t dbSNP:770181391
2853 2853 a, g dbSNP:746059460
2854 2854 a, c dbSNP:781395541
2856 2856 c, t dbSNP:757282952
2858 2858 c, t dbSNP:746974489
2859 2859 a, g dbSNP:371181176
2863 2863 a, g dbSNP:758217844
2882 2882 a, g dbSNP:61756200
2885 2885 a, g dbSNP:764990697
2895 2895 c, t dbSNP:557179689
2896 2896 a, g, t dbSNP:201972198
2897 2897 c, t dbSNP:760044145
2904 2904 c, t dbSNP:189939340
2905 2905 a, g dbSNP:764656850
2913 2913 a, g dbSNP:763524392
2918 2918 a, g dbSNP:776049747
2921 2921 a, g dbSNP:770273474
2925 2925 c, g dbSNP:746170953
2928 2928 c, t dbSNP:138111228
2929 2929 a, g dbSNP:771061948
2941 2941 a, g dbSNP:113436186
2943 2943 c, t dbSNP:747018092
2955 2955 a, c dbSNP:776940641
2957 2957 c, t dbSNP:779542390
2968 2968 a, c dbSNP:35279173
2970 2970 c, t dbSNP:747228179
2976 2976 a, g, t dbSNP:571829920
2979 2979 a, g dbSNP:140221173
2980 2980 a, g dbSNP:748082505
2981 2981 a, g dbSNP:778762924
2988 2988 a, g dbSNP:768517793
2997 2997 a, g dbSNP:748998598
3001 3001 a, g dbSNP:142125913
3003 3003 a, g dbSNP:532043947
3009 3009 a, g dbSNP:755772067
3014 3014 c, t dbSNP:750090759
3021 3021 c, g dbSNP:780920887
3027 3027 c, t dbSNP:138535661
3039 3039 c, t dbSNP:374707313
3044 3044 c, t dbSNP:765796756
3047 3047 a, t dbSNP:760055169
3052 3052 a, g dbSNP:754199351
3056 3056 c, t dbSNP:200982266
3082 3082 c, t dbSNP:760872742
3084 3084 c, g dbSNP:548245892
3085 3085 a, g dbSNP:772150342
3086 3086 g, t dbSNP:761830960
3093 3093 c, t dbSNP:140970138
3094 3094 c, g, t dbSNP:749227253
3097 3097 g, t dbSNP:779772586
3117 3117 a, t dbSNP:774465481
3122 3122 a, g dbSNP:143642103
3129 3129 a, g dbSNP:762868543
3133 3133 a, g dbSNP:775435376
3135 3135 a, g dbSNP:769491603
3144 3144 c, t dbSNP:745613218
3156 3156 a, g dbSNP:559315611
3169 3169 a, t dbSNP:770753645
3184 3184 a, t dbSNP:746642521
3188 3188 c, t dbSNP:777211622
3193 3193 c, g dbSNP:757857474
3216 3216 a, c dbSNP:181250926
3232 3232 a, g dbSNP:757553644
3244 3244 a, g dbSNP:751746803
3251 3251 c, t dbSNP:764332457
3262 3262 c, g dbSNP:777972042
3280 3280 c, t dbSNP:768169551
3288 3288 -, t dbSNP:763732068
3288 3288 a, t dbSNP:750700455
3290 3290 c, t dbSNP:762403752
3300 3300 a, t dbSNP:777158012
3308 3308 c, t dbSNP:771471597
3318 3318 a, g dbSNP:376043190
3322 3322 a, g dbSNP:368876096
3341 3341 c, g dbSNP:199633613
3357 3357 a, g dbSNP:772256750
3371 3371 a, t dbSNP:775033790
3373 3373 c, t dbSNP:764645584
3374 3374 c, t dbSNP:200636478
3393 3393 c, t dbSNP:773531490
3401 3401 c, g dbSNP:772506095
3447 3447 c, t dbSNP:201192423
3449 3449 c, t dbSNP:763858532
3452 3452 c, t dbSNP:758109437
3453 3453 a, g dbSNP:145312304
3487 3487 a, g dbSNP:764815073
3500 3500 c, t dbSNP:141331848
3501 3501 a, c dbSNP:144421302
3504 3504 a, c dbSNP:530278225
3511 3511 c, g dbSNP:544508292
3531 3531 c, t dbSNP:778632183
3555 3555 a, g dbSNP:762476453
3561 3561 c, t dbSNP:200929981
3576 3576 c, t dbSNP:142491497
3587 3587 a, g, t dbSNP:146386562
3588 3588 c, t dbSNP:769952683
3589 3589 a, g dbSNP:759785386
3598 3598 a, c dbSNP:765625619
3600 3600 c, t dbSNP:138956189
3604 3604 a, g dbSNP:769270663
3617 3617 a, c dbSNP:771017653
3618 3618 c, t dbSNP:760702751
3621 3621 c, t dbSNP:79347691
3624 3624 a, c dbSNP:77509921
3634 3634 c, t dbSNP:373669618
3636 3636 g, t dbSNP:149621054
3639 3639 c, t dbSNP:138191914
3646 3646 c, t dbSNP:748906866
3675 3675 a, g dbSNP:201470036
3678 3678 c, t dbSNP:139085875
3679 3679 a, g dbSNP:749994944
3685 3685 c, t dbSNP:780829180
3686 3686 a, g dbSNP:376947712
3701 3701 a, t dbSNP:147007636
3712 3712 a, g, t dbSNP:755317297
3747 3747 c, t dbSNP:768445696
3749 3749 a, g dbSNP:760335389
3759 3759 c, t dbSNP:147850919
3760 3760 c, t dbSNP:767596903
3769 3769 a, g dbSNP:761904937
3779 3779 a, g dbSNP:774187563
3787 3787 c, t dbSNP:765178000
3803 3803 c, t dbSNP:144091208
3804 3804 a, g dbSNP:759378650
3811 3811 c, t dbSNP:373191999
3815 3815 a, g dbSNP:776531286
3858 3858 c, t dbSNP:770642587
3860 3860 g, t dbSNP:760189410
3864 3864 c, t dbSNP:540628434
3891 3891 c, t dbSNP:760443863
3913 3913 c, t dbSNP:3024933
3914 3914 a, g, t dbSNP:779069171
3919 3919 g, t dbSNP:199609035
3936 3936 a, g dbSNP:761281261
3937 3937 c, g dbSNP:773810325
3953 3953 c, t dbSNP:770306554
3969 3969 c, g dbSNP:201150110
3975 3975 c, t dbSNP:781621586
3976 3976 a, g dbSNP:771192197
3978 3978 a, g dbSNP:747310117
4013 4013 c, g dbSNP:777832373
4016 4016 c, g dbSNP:776987023
4024 4024 a, c dbSNP:771372502
4044 4044 c, g dbSNP:747300394
4058 4058 a, g dbSNP:149089413
4059 4059 g, t dbSNP:112819248
4077 4077 a, c, t dbSNP:369720896
4078 4078 g, t dbSNP:755096256
4090 4090 a, c dbSNP:759048381
4122 4122 g, t dbSNP:749296968
4125 4125 c, t dbSNP:779825681
4133 4133 c, t dbSNP:756037985
4134 4134 a, t dbSNP:750206397
4135 4135 c, t dbSNP:202018151
4146 4146 a, g dbSNP:767240927
4158 4158 c, t dbSNP:756905537
4166 4166 a, g dbSNP:751205891
4176 4176 c, t dbSNP:368134591
4177 4177 a, g dbSNP:762343259
4181 4181 a, g dbSNP:777230968
4192 4192 a, t dbSNP:766821566
4193 4193 c, g dbSNP:761189841
4203 4203 a, c, t dbSNP:368928990
4221 4221 a, c dbSNP:764742090
4225 4225 a, g dbSNP:761155615
4226 4226 a, g dbSNP:371989874
4227 4227 c, g dbSNP:768045385
4232 4232 a, c, g dbSNP:774816816
4251 4251 c, t dbSNP:550869545
4252 4252 g, t dbSNP:768782205
4263 4263 a, c dbSNP:763177887
4272 4272 a, t dbSNP:775435740
4277 4277 a, g dbSNP:370218298
4283 4283 a, g dbSNP:111535990
4288 4288 a, g dbSNP:770874469
4289 4289 a, c dbSNP:746885035
4297 4297 c, t dbSNP:772952207
4298 4298 a, g dbSNP:752431273
4329 4329 a, c dbSNP:781093912
4340 4340 c, t dbSNP:771889653
4341 4341 a, c, g dbSNP:139030621
4356 4356 c, t dbSNP:754637298
4365 4365 a, c dbSNP:748831456
4370 4370 -, caa dbSNP:776683947
4371 4371 a, g dbSNP:779652985
4380 4380 g, t dbSNP:757844095
4394 4394 c, g dbSNP:773968889
4403 4403 c, t dbSNP:768437698
4416 4416 c, t dbSNP:748882692
4418 4418 a, c dbSNP:3024906
4423 4423 c, t dbSNP:373725872
4426 4426 c, t dbSNP:199549890
4427 4427 a, c, g dbSNP:376543078
4428 4428 c, t dbSNP:758789071
4430 4430 c, t dbSNP:373617359
4432 4432 a, g dbSNP:765524533
4439 4439 c, g dbSNP:755264465
4446 4446 a, g dbSNP:778533196
4449 4449 a, g dbSNP:370883796
4455 4455 g, t dbSNP:766497133
4456 4456 g, t dbSNP:527418737
4457 4457 c, t dbSNP:750431303
4490 4490 a, g dbSNP:775951674
4499 4499 a, g dbSNP:191594904
4534 4534 a, g dbSNP:3024907
4571 4571 a, g dbSNP:148090220
4572 4572 c, t dbSNP:113109887
4582 4582 c, t dbSNP:574975927
4618 4618 a, t dbSNP:2280236
4627 4627 a, c dbSNP:770091061
4656 4656 c, t dbSNP:753311752

Target ORF information:

RefSeq Version XM_011511704
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens signal transducer and activator of transcription 4 (STAT4), transcript variant X2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011511704

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
ATGAAGTGGG GCAGCTATTT GTCCATCATG TCTCAGTGGA ATCAAGTCCA ACAGTTAGAA 
ATCAAGTTTT TGGAGCAGGT GGATCAATTC TATGATGACA ACTTTCCCAT GGAAATTCGG
CATCTGTTGG CCCAATGGAT TGAAAATCAA GACTGGGAGG CAGCTTCTAA CAATGAAACC
ATGGCAACGA TTCTTCTTCA AAACTTGTTA ATACAACTGG ATGAACAGTT AGGTCGTGTT
TCCAAAGAGA AAAACCTACT CTTGATACAC AATCTAAAAA GAATTAGGAA GGTCCTTCAG
GGAAAATTTC ATGGAAATCC AATGCATGTA GCTGTGGTTA TTTCAAACTG TTTAAGGGAA
GAGAGGAGAA TATTGGCTGC AGCCAACATG CCTGTCCAGG GGCCTCTAGA GAAATCCTTA
CAAAGTTCTT CAGTTTCAGA AAGACAGAGG AATGTGGAGC ACAAAGTGGC TGCCATTAAA
AACAGTGTGC AGATGACAGA ACAAGATACC AAATACTTAG AAGATCTGCA AGACGAATTT
GACTACAGGT ATAAAACAAT TCAGACAATG GATCAGAGTG ACAAGAATAG TGCCATGGTG
AATCAGGAAG TTTTGACACT GCAGGAAATG CTTAACAGCC TCGATTTCAA GAGAAAGGAG
GCTCTCAGTA AAATGACCCA AATCATCCAT GAGACAGACC TGTTAATGAA CACCATGCTC
ATAGAAGAGC TGCAAGACTG GAAGCGGCGG CAGCAAATCG CCTGCATCGG GGGTCCACTC
CACAATGGGC TCGACCAGCT TCAGAACTGC TTTACACTAT TGGCAGAAAG TCTTTTCCAA
CTGAGAAGGC AATTGGAGAA ACTAGAGGAG CAATCTACCA AAATGACATA TGAAGGTGAT
CCCATTCCAA TGCAAAGAAC TCACATGCTA GAAAGAGTCA CCTTCTTGAT CTACAACCTT
TTCAAGAACT CATTTGTGGT TGAGCGACAG CCATGTATGC CAACCCACCC TCAGAGGCCG
TTGGTACTTA AAACCCTAAT TCAGTTCACT GTAAAACTAA GGCTACTAAT AAAATTGCCA
GAACTAAACT ATCAGGTAAA GGTTAAGGCA TCAATTGACA AGAATGTTTC AACTCTAAGC
AACCGAAGAT TTGTACTTTG TGGAACTAAT GTCAAAGCCA TGTCTATTGA AGAATCTTCC
AATGGGAGTC TCTCAGTAGA ATTTCGACAT TTGCAACCAA AGGAAATGAA GTCCAGTGCT
GGAGGTAAAG GAAATGAGGG CTGTCACATG GTGACTGAAG AACTTCATTC CATAACGTTT
GAAACACAGA TCTGCCTCTA TGGCCTGACC ATAGATTTGG AGACCAGCTC ATTGCCTGTG
GTGATGATTT CCAATGTCAG TCAGTTACCT AATGCTTGGG CATCCATCAT TTGGTACAAC
GTGTCAACCA ACGATTCCCA GAACTTGGTT TTCTTTAATA ATCCTCCACC TGCCACATTG
AGTCAACTAC TGGAGGTGAT GAGCTGGCAG TTTTCATCGT ACGTTGGTCG TGGTCTTAAC
TCAGATCAAC TCCATATGCT GGCAGAGAAG CTTACAGTCC AATCTAGCTA CAGTGATGGT
CACCTCACCT GGGCCAAGTT CTGCAAGGAA CATTTACCTG GTAAATCATT TACCTTTTGG
ACATGGCTTG AAGCAATATT GGATCTAATT AAGAAACACA TTCTTCCCCT TTGGATTGAT
GGGTATGTCA TGGGCTTTGT TAGCAAAGAG AAGGAACGGC TGTTGCTAAA GGATAAAATG
CCTGGCACCT TTTTATTAAG ATTCAGTGAA AGCCATCTCG GAGGAATAAC TTTCACCTGG
GTGGACCATT CTGAAAGTGG GGAAGTGAGA TTCCACTCTG TAGAACCCTA CAATAAAGGC
CGGTTGTCTG CTCTGCCATT CGCTGACATC CTGCGAGACT ACAAAGTTAT TATGGCTGAA
AACATTCCTG AAAACCCTCT GAAGTACCTA TATCCTGACA TTCCCAAAGA CAAAGCCTTC
GGTAAACACT ACAGCTCTCA GCCTTGCGAA GTTTCAAGAC CAACAGAAAG GGGTGACAAA
GGTTATGTTC CTTCTGTTTT TATCCCCATC TCAACAATCC GAAGTGATTC AACAGAGCCA
CATTCTCCAT CAGACCTTCT TCCCATGTCT CCAAGTGTGT ATGCGGTGTT GAGAGAAAAC
CTGAGTCCCA CAACAATTGA AACTGCAATG AAGTCTCCTT ATTCTGCTGA ATGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu18290
Accession Version XM_011511705.1
Sequence Information ORF Nucleotide Sequence (Length: 2247bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product signal transducer and activator of transcription 4 isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_005403.18) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
ATGTCTCAGT GGAATCAAGT CCAACAGTTA GAAATCAAGT TTTTGGAGCA GGTGGATCAA 
TTCTATGATG ACAACTTTCC CATGGAAATT CGGCATCTGT TGGCCCAATG GATTGAAAAT
CAAGACTGGG AGGCAGCTTC TAACAATGAA ACCATGGCAA CGATTCTTCT TCAAAACTTG
TTAATACAAC TGGATGAACA GTTAGGTCGT GTTTCCAAAG AGAAAAACCT ACTCTTGATA
CACAATCTAA AAAGAATTAG GAAGGTCCTT CAGGGAAAAT TTCATGGAAA TCCAATGCAT
GTAGCTGTGG TTATTTCAAA CTGTTTAAGG GAAGAGAGGA GAATATTGGC TGCAGCCAAC
ATGCCTGTCC AGGGGCCTCT AGAGAAATCC TTACAAAGTT CTTCAGTTTC AGAAAGACAG
AGGAATGTGG AGCACAAAGT GGCTGCCATT AAAAACAGTG TGCAGATGAC AGAACAAGAT
ACCAAATACT TAGAAGATCT GCAAGACGAA TTTGACTACA GGTATAAAAC AATTCAGACA
ATGGATCAGA GTGACAAGAA TAGTGCCATG GTGAATCAGG AAGTTTTGAC ACTGCAGGAA
ATGCTTAACA GCCTCGATTT CAAGAGAAAG GAGGCTCTCA GTAAAATGAC CCAAATCATC
CATGAGACAG ACCTGTTAAT GAACACCATG CTCATAGAAG AGCTGCAAGA CTGGAAGCGG
CGGCAGCAAA TCGCCTGCAT CGGGGGTCCA CTCCACAATG GGCTCGACCA GCTTCAGAAC
TGCTTTACAC TATTGGCAGA AAGTCTTTTC CAACTGAGAA GGCAATTGGA GAAACTAGAG
GAGCAATCTA CCAAAATGAC ATATGAAGGT GATCCCATTC CAATGCAAAG AACTCACATG
CTAGAAAGAG TCACCTTCTT GATCTACAAC CTTTTCAAGA ACTCATTTGT GGTTGAGCGA
CAGCCATGTA TGCCAACCCA CCCTCAGAGG CCGTTGGTAC TTAAAACCCT AATTCAGTTC
ACTGTAAAAC TAAGGCTACT AATAAAATTG CCAGAACTAA ACTATCAGGT AAAGGTTAAG
GCATCAATTG ACAAGAATGT TTCAACTCTA AGCAACCGAA GATTTGTACT TTGTGGAACT
AATGTCAAAG CCATGTCTAT TGAAGAATCT TCCAATGGGA GTCTCTCAGT AGAATTTCGA
CATTTGCAAC CAAAGGAAAT GAAGTCCAGT GCTGGAGGTA AAGGAAATGA GGGCTGTCAC
ATGGTGACTG AAGAACTTCA TTCCATAACG TTTGAAACAC AGATCTGCCT CTATGGCCTG
ACCATAGATT TGGAGACCAG CTCATTGCCT GTGGTGATGA TTTCCAATGT CAGTCAGTTA
CCTAATGCTT GGGCATCCAT CATTTGGTAC AACGTGTCAA CCAACGATTC CCAGAACTTG
GTTTTCTTTA ATAATCCTCC ACCTGCCACA TTGAGTCAAC TACTGGAGGT GATGAGCTGG
CAGTTTTCAT CGTACGTTGG TCGTGGTCTT AACTCAGATC AACTCCATAT GCTGGCAGAG
AAGCTTACAG TCCAATCTAG CTACAGTGAT GGTCACCTCA CCTGGGCCAA GTTCTGCAAG
GAACATTTAC CTGGTAAATC ATTTACCTTT TGGACATGGC TTGAAGCAAT ATTGGATCTA
ATTAAGAAAC ACATTCTTCC CCTTTGGATT GATGGGTATG TCATGGGCTT TGTTAGCAAA
GAGAAGGAAC GGCTGTTGCT AAAGGATAAA ATGCCTGGCA CCTTTTTATT AAGATTCAGT
GAAAGCCATC TCGGAGGAAT AACTTTCACC TGGGTGGACC ATTCTGAAAG TGGGGAAGTG
AGATTCCACT CTGTAGAACC CTACAATAAA GGCCGGTTGT CTGCTCTGCC ATTCGCTGAC
ATCCTGCGAG ACTACAAAGT TATTATGGCT GAAAACATTC CTGAAAACCC TCTGAAGTAC
CTATATCCTG ACATTCCCAA AGACAAAGCC TTCGGTAAAC ACTACAGCTC TCAGCCTTGC
GAAGTTTCAA GACCAACAGA AAGGGGTGAC AAAGGTTATG TTCCTTCTGT TTTTATCCCC
ATCTCAACAA TCCGAAGTGA TTCAACAGAG CCACATTCTC CATCAGACCT TCTTCCCATG
TCTCCAAGTG TGTATGCGGT GTTGAGAGAA AACCTGAGTC CCACAACAAT TGAAACTGCA
ATGAAGTCTC CTTATTCTGC TGAATGA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqXP_011510007.1
CDS526..2772
Misc Feature(1)529..888(+)
Misc Feature(2)934..1467(+)
Misc Feature(3)1471..2214(+)
Misc Feature(4)2182..2625(+)
Misc Feature(5)2263..2403(+)
Misc Feature(6)2398..2448(+)
Misc Feature(7)2428..2619(+)
Translation
Position Chain Variation Link
1 1 a, g dbSNP:563408234
62 62 a, t dbSNP:559402424
77 77 c, g dbSNP:765581076
113 113 a, g dbSNP:541906168
122 122 a, g dbSNP:574621309
209 209 a, g dbSNP:546256475
213 213 a, c dbSNP:192610101
229 229 a, g dbSNP:370231404
233 233 a, c dbSNP:115556152
238 238 a, g dbSNP:187644592
275 275 a, g dbSNP:748791142
290 290 g, t dbSNP:781574343
308 308 c, g dbSNP:530512364
363 363 c, t dbSNP:148076554
366 366 a, g dbSNP:541906648
368 368 ag, tc dbSNP:386653777
368 368 a, t dbSNP:111347725
369 369 c, g dbSNP:111744432
377 377 c, g dbSNP:139069727
397 397 c, g dbSNP:756270368
403 403 c, t dbSNP:544218159
404 404 a, g dbSNP:115067441
421 421 a, g dbSNP:13030488
428 428 a, g dbSNP:754930172
453 453 c, t dbSNP:115888144
502 502 a, t dbSNP:146501907
545 545 c, t dbSNP:778760914
561 561 a, c dbSNP:754787268
567 567 c, t dbSNP:753587179
621 621 g, t dbSNP:766134008
630 630 a, c dbSNP:760427388
633 633 a, g dbSNP:750034868
639 639 c, t dbSNP:35500382
650 650 a, g dbSNP:761161672
660 660 a, g dbSNP:756950986
686 686 c, t dbSNP:750095435
708 708 a, g dbSNP:767019947
727 727 -, ttag dbSNP:766324016
732 732 a, t dbSNP:369256225
734 734 g, t dbSNP:751076320
740 740 c, t dbSNP:267599129
742 742 a, g dbSNP:763673195
760 760 c, t dbSNP:760176547
770 770 a, g dbSNP:777271668
774 774 a, g dbSNP:546810787
785 785 a, g dbSNP:202184860
797 797 a, g dbSNP:773503051
808 808 c, t dbSNP:757999757
820 820 a, g dbSNP:752105122
827 827 c, t dbSNP:778453112
835 835 a, g dbSNP:756625612
843 843 a, g dbSNP:3024838
849 849 c, t dbSNP:560856047
858 858 a, g dbSNP:762103216
868 868 a, g dbSNP:3024839
877 877 a, g dbSNP:372012413
883 883 a, g dbSNP:763055396
885 885 c, t dbSNP:775474969
899 899 a, g dbSNP:773188982
900 900 a, g dbSNP:771977877
908 908 a, t dbSNP:140675301
915 915 c, t dbSNP:145071895
916 916 c, t dbSNP:768064931
952 952 a, g, t dbSNP:370819441
957 957 a, g dbSNP:757804856
967 967 c, g dbSNP:747495835
971 971 c, t dbSNP:778170459
977 977 c, t dbSNP:551175992
985 985 a, g dbSNP:758720903
992 992 c, t dbSNP:376677137
994 994 a, g dbSNP:372399682
1007 1007 c, t dbSNP:775033600
1014 1014 -, ctta dbSNP:779446409
1029 1029 a, g dbSNP:35918099
1032 1032 c, t dbSNP:199940585
1045 1045 a, g dbSNP:778192508
1054 1054 a, g dbSNP:758709109
1056 1056 a, g dbSNP:748501058
1068 1068 c, g dbSNP:779115246
1075 1075 a, g dbSNP:757114207
1084 1084 a, t dbSNP:769304507
1095 1095 c, g dbSNP:543324204
1128 1128 a, g dbSNP:773619472
1131 1131 a, t dbSNP:74378111
1137 1137 a, c dbSNP:144713478
1140 1140 c, g dbSNP:753599408
1155 1155 a, g dbSNP:367890072
1159 1159 a, g dbSNP:757165202
1165 1165 a, g dbSNP:145218540
1175 1175 c, t dbSNP:778253892
1179 1179 a, g dbSNP:139598810
1180 1180 a, g dbSNP:749622712
1187 1187 a, g dbSNP:780454944
1205 1205 c, t dbSNP:770181391
1215 1215 a, g dbSNP:746059460
1216 1216 a, c dbSNP:781395541
1218 1218 c, t dbSNP:757282952
1220 1220 c, t dbSNP:746974489
1221 1221 a, g dbSNP:371181176
1225 1225 a, g dbSNP:758217844
1244 1244 a, g dbSNP:61756200
1247 1247 a, g dbSNP:764990697
1257 1257 c, t dbSNP:557179689
1258 1258 a, g, t dbSNP:201972198
1259 1259 c, t dbSNP:760044145
1266 1266 c, t dbSNP:189939340
1267 1267 a, g dbSNP:764656850
1275 1275 a, g dbSNP:763524392
1280 1280 a, g dbSNP:776049747
1283 1283 a, g dbSNP:770273474
1287 1287 c, g dbSNP:746170953
1290 1290 c, t dbSNP:138111228
1291 1291 a, g dbSNP:771061948
1303 1303 a, g dbSNP:113436186
1305 1305 c, t dbSNP:747018092
1317 1317 a, c dbSNP:776940641
1319 1319 c, t dbSNP:779542390
1330 1330 a, c dbSNP:35279173
1332 1332 c, t dbSNP:747228179
1338 1338 a, g, t dbSNP:571829920
1341 1341 a, g dbSNP:140221173
1342 1342 a, g dbSNP:748082505
1343 1343 a, g dbSNP:778762924
1350 1350 a, g dbSNP:768517793
1359 1359 a, g dbSNP:748998598
1363 1363 a, g dbSNP:142125913
1365 1365 a, g dbSNP:532043947
1371 1371 a, g dbSNP:755772067
1376 1376 c, t dbSNP:750090759
1383 1383 c, g dbSNP:780920887
1389 1389 c, t dbSNP:138535661
1401 1401 c, t dbSNP:374707313
1406 1406 c, t dbSNP:765796756
1409 1409 a, t dbSNP:760055169
1414 1414 a, g dbSNP:754199351
1418 1418 c, t dbSNP:200982266
1444 1444 c, t dbSNP:760872742
1446 1446 c, g dbSNP:548245892
1447 1447 a, g dbSNP:772150342
1448 1448 g, t dbSNP:761830960
1455 1455 c, t dbSNP:140970138
1456 1456 c, g, t dbSNP:749227253
1459 1459 g, t dbSNP:779772586
1479 1479 a, t dbSNP:774465481
1484 1484 a, g dbSNP:143642103
1491 1491 a, g dbSNP:762868543
1495 1495 a, g dbSNP:775435376
1497 1497 a, g dbSNP:769491603
1506 1506 c, t dbSNP:745613218
1518 1518 a, g dbSNP:559315611
1531 1531 a, t dbSNP:770753645
1546 1546 a, t dbSNP:746642521
1550 1550 c, t dbSNP:777211622
1555 1555 c, g dbSNP:757857474
1578 1578 a, c dbSNP:181250926
1594 1594 a, g dbSNP:757553644
1606 1606 a, g dbSNP:751746803
1613 1613 c, t dbSNP:764332457
1624 1624 c, g dbSNP:777972042
1642 1642 c, t dbSNP:768169551
1650 1650 -, t dbSNP:763732068
1650 1650 a, t dbSNP:750700455
1652 1652 c, t dbSNP:762403752
1662 1662 a, t dbSNP:777158012
1670 1670 c, t dbSNP:771471597
1680 1680 a, g dbSNP:376043190
1684 1684 a, g dbSNP:368876096
1703 1703 c, g dbSNP:199633613
1719 1719 a, g dbSNP:772256750
1733 1733 a, t dbSNP:775033790
1735 1735 c, t dbSNP:764645584
1736 1736 c, t dbSNP:200636478
1755 1755 c, t dbSNP:773531490
1763 1763 c, g dbSNP:772506095
1809 1809 c, t dbSNP:201192423
1811 1811 c, t dbSNP:763858532
1814 1814 c, t dbSNP:758109437
1815 1815 a, g dbSNP:145312304
1849 1849 a, g dbSNP:764815073
1862 1862 c, t dbSNP:141331848
1863 1863 a, c dbSNP:144421302
1866 1866 a, c dbSNP:530278225
1873 1873 c, g dbSNP:544508292
1893 1893 c, t dbSNP:778632183
1917 1917 a, g dbSNP:762476453
1923 1923 c, t dbSNP:200929981
1938 1938 c, t dbSNP:142491497
1949 1949 a, g, t dbSNP:146386562
1950 1950 c, t dbSNP:769952683
1951 1951 a, g dbSNP:759785386
1960 1960 a, c dbSNP:765625619
1962 1962 c, t dbSNP:138956189
1966 1966 a, g dbSNP:769270663
1979 1979 a, c dbSNP:771017653
1980 1980 c, t dbSNP:760702751
1983 1983 c, t dbSNP:79347691
1986 1986 a, c dbSNP:77509921
1996 1996 c, t dbSNP:373669618
1998 1998 g, t dbSNP:149621054
2001 2001 c, t dbSNP:138191914
2008 2008 c, t dbSNP:748906866
2037 2037 a, g dbSNP:201470036
2040 2040 c, t dbSNP:139085875
2041 2041 a, g dbSNP:749994944
2047 2047 c, t dbSNP:780829180
2048 2048 a, g dbSNP:376947712
2063 2063 a, t dbSNP:147007636
2074 2074 a, g, t dbSNP:755317297
2109 2109 c, t dbSNP:768445696
2111 2111 a, g dbSNP:760335389
2121 2121 c, t dbSNP:147850919
2122 2122 c, t dbSNP:767596903
2131 2131 a, g dbSNP:761904937
2141 2141 a, g dbSNP:774187563
2149 2149 c, t dbSNP:765178000
2165 2165 c, t dbSNP:144091208
2166 2166 a, g dbSNP:759378650
2173 2173 c, t dbSNP:373191999
2177 2177 a, g dbSNP:776531286
2220 2220 c, t dbSNP:770642587
2222 2222 g, t dbSNP:760189410
2226 2226 c, t dbSNP:540628434
2253 2253 c, t dbSNP:760443863
2275 2275 c, t dbSNP:3024933
2276 2276 a, g, t dbSNP:779069171
2281 2281 g, t dbSNP:199609035
2298 2298 a, g dbSNP:761281261
2299 2299 c, g dbSNP:773810325
2315 2315 c, t dbSNP:770306554
2331 2331 c, g dbSNP:201150110
2337 2337 c, t dbSNP:781621586
2338 2338 a, g dbSNP:771192197
2340 2340 a, g dbSNP:747310117
2375 2375 c, g dbSNP:777832373
2378 2378 c, g dbSNP:776987023
2386 2386 a, c dbSNP:771372502
2406 2406 c, g dbSNP:747300394
2420 2420 a, g dbSNP:149089413
2421 2421 g, t dbSNP:112819248
2439 2439 a, c, t dbSNP:369720896
2440 2440 g, t dbSNP:755096256
2452 2452 a, c dbSNP:759048381
2484 2484 g, t dbSNP:749296968
2487 2487 c, t dbSNP:779825681
2495 2495 c, t dbSNP:756037985
2496 2496 a, t dbSNP:750206397
2497 2497 c, t dbSNP:202018151
2508 2508 a, g dbSNP:767240927
2520 2520 c, t dbSNP:756905537
2528 2528 a, g dbSNP:751205891
2538 2538 c, t dbSNP:368134591
2539 2539 a, g dbSNP:762343259
2543 2543 a, g dbSNP:777230968
2554 2554 a, t dbSNP:766821566
2555 2555 c, g dbSNP:761189841
2565 2565 a, c, t dbSNP:368928990
2583 2583 a, c dbSNP:764742090
2587 2587 a, g dbSNP:761155615
2588 2588 a, g dbSNP:371989874
2589 2589 c, g dbSNP:768045385
2594 2594 a, c, g dbSNP:774816816
2613 2613 c, t dbSNP:550869545
2614 2614 g, t dbSNP:768782205
2625 2625 a, c dbSNP:763177887
2634 2634 a, t dbSNP:775435740
2639 2639 a, g dbSNP:370218298
2645 2645 a, g dbSNP:111535990
2650 2650 a, g dbSNP:770874469
2651 2651 a, c dbSNP:746885035
2659 2659 c, t dbSNP:772952207
2660 2660 a, g dbSNP:752431273
2691 2691 a, c dbSNP:781093912
2702 2702 c, t dbSNP:771889653
2703 2703 a, c, g dbSNP:139030621
2718 2718 c, t dbSNP:754637298
2727 2727 a, c dbSNP:748831456
2732 2732 -, caa dbSNP:776683947
2733 2733 a, g dbSNP:779652985
2742 2742 g, t dbSNP:757844095
2756 2756 c, g dbSNP:773968889
2765 2765 c, t dbSNP:768437698
2778 2778 c, t dbSNP:748882692
2780 2780 a, c dbSNP:3024906
2785 2785 c, t dbSNP:373725872
2788 2788 c, t dbSNP:199549890
2789 2789 a, c, g dbSNP:376543078
2790 2790 c, t dbSNP:758789071
2792 2792 c, t dbSNP:373617359
2794 2794 a, g dbSNP:765524533
2801 2801 c, g dbSNP:755264465
2808 2808 a, g dbSNP:778533196
2811 2811 a, g dbSNP:370883796
2817 2817 g, t dbSNP:766497133
2818 2818 g, t dbSNP:527418737
2819 2819 c, t dbSNP:750431303
2852 2852 a, g dbSNP:775951674
2861 2861 a, g dbSNP:191594904
2896 2896 a, g dbSNP:3024907
2933 2933 a, g dbSNP:148090220
2934 2934 c, t dbSNP:113109887
2944 2944 c, t dbSNP:574975927
2980 2980 a, t dbSNP:2280236
2989 2989 a, c dbSNP:770091061
3018 3018 c, t dbSNP:753311752

Target ORF information:

RefSeq Version XM_011511705
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens signal transducer and activator of transcription 4 (STAT4), transcript variant X3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011511705

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
ATGTCTCAGT GGAATCAAGT CCAACAGTTA GAAATCAAGT TTTTGGAGCA GGTGGATCAA 
TTCTATGATG ACAACTTTCC CATGGAAATT CGGCATCTGT TGGCCCAATG GATTGAAAAT
CAAGACTGGG AGGCAGCTTC TAACAATGAA ACCATGGCAA CGATTCTTCT TCAAAACTTG
TTAATACAAC TGGATGAACA GTTAGGTCGT GTTTCCAAAG AGAAAAACCT ACTCTTGATA
CACAATCTAA AAAGAATTAG GAAGGTCCTT CAGGGAAAAT TTCATGGAAA TCCAATGCAT
GTAGCTGTGG TTATTTCAAA CTGTTTAAGG GAAGAGAGGA GAATATTGGC TGCAGCCAAC
ATGCCTGTCC AGGGGCCTCT AGAGAAATCC TTACAAAGTT CTTCAGTTTC AGAAAGACAG
AGGAATGTGG AGCACAAAGT GGCTGCCATT AAAAACAGTG TGCAGATGAC AGAACAAGAT
ACCAAATACT TAGAAGATCT GCAAGACGAA TTTGACTACA GGTATAAAAC AATTCAGACA
ATGGATCAGA GTGACAAGAA TAGTGCCATG GTGAATCAGG AAGTTTTGAC ACTGCAGGAA
ATGCTTAACA GCCTCGATTT CAAGAGAAAG GAGGCTCTCA GTAAAATGAC CCAAATCATC
CATGAGACAG ACCTGTTAAT GAACACCATG CTCATAGAAG AGCTGCAAGA CTGGAAGCGG
CGGCAGCAAA TCGCCTGCAT CGGGGGTCCA CTCCACAATG GGCTCGACCA GCTTCAGAAC
TGCTTTACAC TATTGGCAGA AAGTCTTTTC CAACTGAGAA GGCAATTGGA GAAACTAGAG
GAGCAATCTA CCAAAATGAC ATATGAAGGT GATCCCATTC CAATGCAAAG AACTCACATG
CTAGAAAGAG TCACCTTCTT GATCTACAAC CTTTTCAAGA ACTCATTTGT GGTTGAGCGA
CAGCCATGTA TGCCAACCCA CCCTCAGAGG CCGTTGGTAC TTAAAACCCT AATTCAGTTC
ACTGTAAAAC TAAGGCTACT AATAAAATTG CCAGAACTAA ACTATCAGGT AAAGGTTAAG
GCATCAATTG ACAAGAATGT TTCAACTCTA AGCAACCGAA GATTTGTACT TTGTGGAACT
AATGTCAAAG CCATGTCTAT TGAAGAATCT TCCAATGGGA GTCTCTCAGT AGAATTTCGA
CATTTGCAAC CAAAGGAAAT GAAGTCCAGT GCTGGAGGTA AAGGAAATGA GGGCTGTCAC
ATGGTGACTG AAGAACTTCA TTCCATAACG TTTGAAACAC AGATCTGCCT CTATGGCCTG
ACCATAGATT TGGAGACCAG CTCATTGCCT GTGGTGATGA TTTCCAATGT CAGTCAGTTA
CCTAATGCTT GGGCATCCAT CATTTGGTAC AACGTGTCAA CCAACGATTC CCAGAACTTG
GTTTTCTTTA ATAATCCTCC ACCTGCCACA TTGAGTCAAC TACTGGAGGT GATGAGCTGG
CAGTTTTCAT CGTACGTTGG TCGTGGTCTT AACTCAGATC AACTCCATAT GCTGGCAGAG
AAGCTTACAG TCCAATCTAG CTACAGTGAT GGTCACCTCA CCTGGGCCAA GTTCTGCAAG
GAACATTTAC CTGGTAAATC ATTTACCTTT TGGACATGGC TTGAAGCAAT ATTGGATCTA
ATTAAGAAAC ACATTCTTCC CCTTTGGATT GATGGGTATG TCATGGGCTT TGTTAGCAAA
GAGAAGGAAC GGCTGTTGCT AAAGGATAAA ATGCCTGGCA CCTTTTTATT AAGATTCAGT
GAAAGCCATC TCGGAGGAAT AACTTTCACC TGGGTGGACC ATTCTGAAAG TGGGGAAGTG
AGATTCCACT CTGTAGAACC CTACAATAAA GGCCGGTTGT CTGCTCTGCC ATTCGCTGAC
ATCCTGCGAG ACTACAAAGT TATTATGGCT GAAAACATTC CTGAAAACCC TCTGAAGTAC
CTATATCCTG ACATTCCCAA AGACAAAGCC TTCGGTAAAC ACTACAGCTC TCAGCCTTGC
GAAGTTTCAA GACCAACAGA AAGGGGTGAC AAAGGTTATG TTCCTTCTGT TTTTATCCCC
ATCTCAACAA TCCGAAGTGA TTCAACAGAG CCACATTCTC CATCAGACCT TCTTCCCATG
TCTCCAAGTG TGTATGCGGT GTTGAGAGAA AACCTGAGTC CCACAACAAT TGAAACTGCA
ATGAAGTCTC CTTATTCTGC TGAATGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu18290
Accession Version XM_006712719.2
Sequence Information ORF Nucleotide Sequence (Length: 2247bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product signal transducer and activator of transcription 4 isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_005403.18) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 12, 2015 this sequence version replaced gi:578804823. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
ATGTCTCAGT GGAATCAAGT CCAACAGTTA GAAATCAAGT TTTTGGAGCA GGTGGATCAA 
TTCTATGATG ACAACTTTCC CATGGAAATT CGGCATCTGT TGGCCCAATG GATTGAAAAT
CAAGACTGGG AGGCAGCTTC TAACAATGAA ACCATGGCAA CGATTCTTCT TCAAAACTTG
TTAATACAAC TGGATGAACA GTTAGGTCGT GTTTCCAAAG AGAAAAACCT ACTCTTGATA
CACAATCTAA AAAGAATTAG GAAGGTCCTT CAGGGAAAAT TTCATGGAAA TCCAATGCAT
GTAGCTGTGG TTATTTCAAA CTGTTTAAGG GAAGAGAGGA GAATATTGGC TGCAGCCAAC
ATGCCTGTCC AGGGGCCTCT AGAGAAATCC TTACAAAGTT CTTCAGTTTC AGAAAGACAG
AGGAATGTGG AGCACAAAGT GGCTGCCATT AAAAACAGTG TGCAGATGAC AGAACAAGAT
ACCAAATACT TAGAAGATCT GCAAGACGAA TTTGACTACA GGTATAAAAC AATTCAGACA
ATGGATCAGA GTGACAAGAA TAGTGCCATG GTGAATCAGG AAGTTTTGAC ACTGCAGGAA
ATGCTTAACA GCCTCGATTT CAAGAGAAAG GAGGCTCTCA GTAAAATGAC CCAAATCATC
CATGAGACAG ACCTGTTAAT GAACACCATG CTCATAGAAG AGCTGCAAGA CTGGAAGCGG
CGGCAGCAAA TCGCCTGCAT CGGGGGTCCA CTCCACAATG GGCTCGACCA GCTTCAGAAC
TGCTTTACAC TATTGGCAGA AAGTCTTTTC CAACTGAGAA GGCAATTGGA GAAACTAGAG
GAGCAATCTA CCAAAATGAC ATATGAAGGT GATCCCATTC CAATGCAAAG AACTCACATG
CTAGAAAGAG TCACCTTCTT GATCTACAAC CTTTTCAAGA ACTCATTTGT GGTTGAGCGA
CAGCCATGTA TGCCAACCCA CCCTCAGAGG CCGTTGGTAC TTAAAACCCT AATTCAGTTC
ACTGTAAAAC TAAGGCTACT AATAAAATTG CCAGAACTAA ACTATCAGGT AAAGGTTAAG
GCATCAATTG ACAAGAATGT TTCAACTCTA AGCAACCGAA GATTTGTACT TTGTGGAACT
AATGTCAAAG CCATGTCTAT TGAAGAATCT TCCAATGGGA GTCTCTCAGT AGAATTTCGA
CATTTGCAAC CAAAGGAAAT GAAGTCCAGT GCTGGAGGTA AAGGAAATGA GGGCTGTCAC
ATGGTGACTG AAGAACTTCA TTCCATAACG TTTGAAACAC AGATCTGCCT CTATGGCCTG
ACCATAGATT TGGAGACCAG CTCATTGCCT GTGGTGATGA TTTCCAATGT CAGTCAGTTA
CCTAATGCTT GGGCATCCAT CATTTGGTAC AACGTGTCAA CCAACGATTC CCAGAACTTG
GTTTTCTTTA ATAATCCTCC ACCTGCCACA TTGAGTCAAC TACTGGAGGT GATGAGCTGG
CAGTTTTCAT CGTACGTTGG TCGTGGTCTT AACTCAGATC AACTCCATAT GCTGGCAGAG
AAGCTTACAG TCCAATCTAG CTACAGTGAT GGTCACCTCA CCTGGGCCAA GTTCTGCAAG
GAACATTTAC CTGGTAAATC ATTTACCTTT TGGACATGGC TTGAAGCAAT ATTGGATCTA
ATTAAGAAAC ACATTCTTCC CCTTTGGATT GATGGGTATG TCATGGGCTT TGTTAGCAAA
GAGAAGGAAC GGCTGTTGCT AAAGGATAAA ATGCCTGGCA CCTTTTTATT AAGATTCAGT
GAAAGCCATC TCGGAGGAAT AACTTTCACC TGGGTGGACC ATTCTGAAAG TGGGGAAGTG
AGATTCCACT CTGTAGAACC CTACAATAAA GGCCGGTTGT CTGCTCTGCC ATTCGCTGAC
ATCCTGCGAG ACTACAAAGT TATTATGGCT GAAAACATTC CTGAAAACCC TCTGAAGTAC
CTATATCCTG ACATTCCCAA AGACAAAGCC TTCGGTAAAC ACTACAGCTC TCAGCCTTGC
GAAGTTTCAA GACCAACAGA AAGGGGTGAC AAAGGTTATG TTCCTTCTGT TTTTATCCCC
ATCTCAACAA TCCGAAGTGA TTCAACAGAG CCACATTCTC CATCAGACCT TCTTCCCATG
TCTCCAAGTG TGTATGCGGT GTTGAGAGAA AACCTGAGTC CCACAACAAT TGAAACTGCA
ATGAAGTCTC CTTATTCTGC TGAATGA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqXP_006712782.1
CDS24..2270
Misc Feature(1)27..386(+)
Misc Feature(2)432..965(+)
Misc Feature(3)969..1712(+)
Misc Feature(4)1680..2123(+)
Misc Feature(5)1761..1901(+)
Misc Feature(6)1896..1946(+)
Misc Feature(7)1926..2117(+)
Translation
Position Chain Variation Link
43 43 c, t dbSNP:778760914
59 59 a, c dbSNP:754787268
65 65 c, t dbSNP:753587179
119 119 g, t dbSNP:766134008
128 128 a, c dbSNP:760427388
131 131 a, g dbSNP:750034868
137 137 c, t dbSNP:35500382
148 148 a, g dbSNP:761161672
158 158 a, g dbSNP:756950986
184 184 c, t dbSNP:750095435
206 206 a, g dbSNP:767019947
225 225 -, ttag dbSNP:766324016
230 230 a, t dbSNP:369256225
232 232 g, t dbSNP:751076320
238 238 c, t dbSNP:267599129
240 240 a, g dbSNP:763673195
258 258 c, t dbSNP:760176547
268 268 a, g dbSNP:777271668
272 272 a, g dbSNP:546810787
283 283 a, g dbSNP:202184860
295 295 a, g dbSNP:773503051
306 306 c, t dbSNP:757999757
318 318 a, g dbSNP:752105122
325 325 c, t dbSNP:778453112
333 333 a, g dbSNP:756625612
341 341 a, g dbSNP:3024838
347 347 c, t dbSNP:560856047
356 356 a, g dbSNP:762103216
366 366 a, g dbSNP:3024839
375 375 a, g dbSNP:372012413
381 381 a, g dbSNP:763055396
383 383 c, t dbSNP:775474969
397 397 a, g dbSNP:773188982
398 398 a, g dbSNP:771977877
406 406 a, t dbSNP:140675301
413 413 c, t dbSNP:145071895
414 414 c, t dbSNP:768064931
450 450 a, g, t dbSNP:370819441
455 455 a, g dbSNP:757804856
465 465 c, g dbSNP:747495835
469 469 c, t dbSNP:778170459
475 475 c, t dbSNP:551175992
483 483 a, g dbSNP:758720903
490 490 c, t dbSNP:376677137
492 492 a, g dbSNP:372399682
505 505 c, t dbSNP:775033600
512 512 -, ctta dbSNP:779446409
527 527 a, g dbSNP:35918099
530 530 c, t dbSNP:199940585
543 543 a, g dbSNP:778192508
552 552 a, g dbSNP:758709109
554 554 a, g dbSNP:748501058
566 566 c, g dbSNP:779115246
573 573 a, g dbSNP:757114207
582 582 a, t dbSNP:769304507
593 593 c, g dbSNP:543324204
626 626 a, g dbSNP:773619472
629 629 a, t dbSNP:74378111
635 635 a, c dbSNP:144713478
638 638 c, g dbSNP:753599408
653 653 a, g dbSNP:367890072
657 657 a, g dbSNP:757165202
663 663 a, g dbSNP:145218540
673 673 c, t dbSNP:778253892
677 677 a, g dbSNP:139598810
678 678 a, g dbSNP:749622712
685 685 a, g dbSNP:780454944
703 703 c, t dbSNP:770181391
713 713 a, g dbSNP:746059460
714 714 a, c dbSNP:781395541
716 716 c, t dbSNP:757282952
718 718 c, t dbSNP:746974489
719 719 a, g dbSNP:371181176
723 723 a, g dbSNP:758217844
742 742 a, g dbSNP:61756200
745 745 a, g dbSNP:764990697
755 755 c, t dbSNP:557179689
756 756 a, g, t dbSNP:201972198
757 757 c, t dbSNP:760044145
764 764 c, t dbSNP:189939340
765 765 a, g dbSNP:764656850
773 773 a, g dbSNP:763524392
778 778 a, g dbSNP:776049747
781 781 a, g dbSNP:770273474
785 785 c, g dbSNP:746170953
788 788 c, t dbSNP:138111228
789 789 a, g dbSNP:771061948
801 801 a, g dbSNP:113436186
803 803 c, t dbSNP:747018092
815 815 a, c dbSNP:776940641
817 817 c, t dbSNP:779542390
828 828 a, c dbSNP:35279173
830 830 c, t dbSNP:747228179
836 836 a, g, t dbSNP:571829920
839 839 a, g dbSNP:140221173
840 840 a, g dbSNP:748082505
841 841 a, g dbSNP:778762924
848 848 a, g dbSNP:768517793
857 857 a, g dbSNP:748998598
861 861 a, g dbSNP:142125913
863 863 a, g dbSNP:532043947
869 869 a, g dbSNP:755772067
874 874 c, t dbSNP:750090759
881 881 c, g dbSNP:780920887
887 887 c, t dbSNP:138535661
899 899 c, t dbSNP:374707313
904 904 c, t dbSNP:765796756
907 907 a, t dbSNP:760055169
912 912 a, g dbSNP:754199351
916 916 c, t dbSNP:200982266
942 942 c, t dbSNP:760872742
944 944 c, g dbSNP:548245892
945 945 a, g dbSNP:772150342
946 946 g, t dbSNP:761830960
953 953 c, t dbSNP:140970138
954 954 c, g, t dbSNP:749227253
957 957 g, t dbSNP:779772586
977 977 a, t dbSNP:774465481
982 982 a, g dbSNP:143642103
989 989 a, g dbSNP:762868543
993 993 a, g dbSNP:775435376
995 995 a, g dbSNP:769491603
1004 1004 c, t dbSNP:745613218
1016 1016 a, g dbSNP:559315611
1029 1029 a, t dbSNP:770753645
1044 1044 a, t dbSNP:746642521
1048 1048 c, t dbSNP:777211622
1053 1053 c, g dbSNP:757857474
1076 1076 a, c dbSNP:181250926
1092 1092 a, g dbSNP:757553644
1104 1104 a, g dbSNP:751746803
1111 1111 c, t dbSNP:764332457
1122 1122 c, g dbSNP:777972042
1140 1140 c, t dbSNP:768169551
1148 1148 -, t dbSNP:763732068
1148 1148 a, t dbSNP:750700455
1150 1150 c, t dbSNP:762403752
1160 1160 a, t dbSNP:777158012
1168 1168 c, t dbSNP:771471597
1178 1178 a, g dbSNP:376043190
1182 1182 a, g dbSNP:368876096
1201 1201 c, g dbSNP:199633613
1217 1217 a, g dbSNP:772256750
1231 1231 a, t dbSNP:775033790
1233 1233 c, t dbSNP:764645584
1234 1234 c, t dbSNP:200636478
1253 1253 c, t dbSNP:773531490
1261 1261 c, g dbSNP:772506095
1307 1307 c, t dbSNP:201192423
1309 1309 c, t dbSNP:763858532
1312 1312 c, t dbSNP:758109437
1313 1313 a, g dbSNP:145312304
1347 1347 a, g dbSNP:764815073
1360 1360 c, t dbSNP:141331848
1361 1361 a, c dbSNP:144421302
1364 1364 a, c dbSNP:530278225
1371 1371 c, g dbSNP:544508292
1391 1391 c, t dbSNP:778632183
1415 1415 a, g dbSNP:762476453
1421 1421 c, t dbSNP:200929981
1436 1436 c, t dbSNP:142491497
1447 1447 a, g, t dbSNP:146386562
1448 1448 c, t dbSNP:769952683
1449 1449 a, g dbSNP:759785386
1458 1458 a, c dbSNP:765625619
1460 1460 c, t dbSNP:138956189
1464 1464 a, g dbSNP:769270663
1477 1477 a, c dbSNP:771017653
1478 1478 c, t dbSNP:760702751
1481 1481 c, t dbSNP:79347691
1484 1484 a, c dbSNP:77509921
1494 1494 c, t dbSNP:373669618
1496 1496 g, t dbSNP:149621054
1499 1499 c, t dbSNP:138191914
1506 1506 c, t dbSNP:748906866
1535 1535 a, g dbSNP:201470036
1538 1538 c, t dbSNP:139085875
1539 1539 a, g dbSNP:749994944
1545 1545 c, t dbSNP:780829180
1546 1546 a, g dbSNP:376947712
1561 1561 a, t dbSNP:147007636
1572 1572 a, g, t dbSNP:755317297
1607 1607 c, t dbSNP:768445696
1609 1609 a, g dbSNP:760335389
1619 1619 c, t dbSNP:147850919
1620 1620 c, t dbSNP:767596903
1629 1629 a, g dbSNP:761904937
1639 1639 a, g dbSNP:774187563
1647 1647 c, t dbSNP:765178000
1663 1663 c, t dbSNP:144091208
1664 1664 a, g dbSNP:759378650
1671 1671 c, t dbSNP:373191999
1675 1675 a, g dbSNP:776531286
1718 1718 c, t dbSNP:770642587
1720 1720 g, t dbSNP:760189410
1724 1724 c, t dbSNP:540628434
1751 1751 c, t dbSNP:760443863
1773 1773 c, t dbSNP:3024933
1774 1774 a, g, t dbSNP:779069171
1779 1779 g, t dbSNP:199609035
1796 1796 a, g dbSNP:761281261
1797 1797 c, g dbSNP:773810325
1813 1813 c, t dbSNP:770306554
1829 1829 c, g dbSNP:201150110
1835 1835 c, t dbSNP:781621586
1836 1836 a, g dbSNP:771192197
1838 1838 a, g dbSNP:747310117
1873 1873 c, g dbSNP:777832373
1876 1876 c, g dbSNP:776987023
1884 1884 a, c dbSNP:771372502
1904 1904 c, g dbSNP:747300394
1918 1918 a, g dbSNP:149089413
1919 1919 g, t dbSNP:112819248
1937 1937 a, c, t dbSNP:369720896
1938 1938 g, t dbSNP:755096256
1950 1950 a, c dbSNP:759048381
1982 1982 g, t dbSNP:749296968
1985 1985 c, t dbSNP:779825681
1993 1993 c, t dbSNP:756037985
1994 1994 a, t dbSNP:750206397
1995 1995 c, t dbSNP:202018151
2006 2006 a, g dbSNP:767240927
2018 2018 c, t dbSNP:756905537
2026 2026 a, g dbSNP:751205891
2036 2036 c, t dbSNP:368134591
2037 2037 a, g dbSNP:762343259
2041 2041 a, g dbSNP:777230968
2052 2052 a, t dbSNP:766821566
2053 2053 c, g dbSNP:761189841
2063 2063 a, c, t dbSNP:368928990
2081 2081 a, c dbSNP:764742090
2085 2085 a, g dbSNP:761155615
2086 2086 a, g dbSNP:371989874
2087 2087 c, g dbSNP:768045385
2092 2092 a, c, g dbSNP:774816816
2111 2111 c, t dbSNP:550869545
2112 2112 g, t dbSNP:768782205
2123 2123 a, c dbSNP:763177887
2132 2132 a, t dbSNP:775435740
2137 2137 a, g dbSNP:370218298
2143 2143 a, g dbSNP:111535990
2148 2148 a, g dbSNP:770874469
2149 2149 a, c dbSNP:746885035
2157 2157 c, t dbSNP:772952207
2158 2158 a, g dbSNP:752431273
2189 2189 a, c dbSNP:781093912
2200 2200 c, t dbSNP:771889653
2201 2201 a, c, g dbSNP:139030621
2216 2216 c, t dbSNP:754637298
2225 2225 a, c dbSNP:748831456
2230 2230 -, caa dbSNP:776683947
2231 2231 a, g dbSNP:779652985
2240 2240 g, t dbSNP:757844095
2254 2254 c, g dbSNP:773968889
2263 2263 c, t dbSNP:768437698
2276 2276 c, t dbSNP:748882692
2278 2278 a, c dbSNP:3024906
2283 2283 c, t dbSNP:373725872
2286 2286 c, t dbSNP:199549890
2287 2287 a, c, g dbSNP:376543078
2288 2288 c, t dbSNP:758789071
2290 2290 c, t dbSNP:373617359
2292 2292 a, g dbSNP:765524533
2299 2299 c, g dbSNP:755264465
2306 2306 a, g dbSNP:778533196
2309 2309 a, g dbSNP:370883796
2315 2315 g, t dbSNP:766497133
2316 2316 g, t dbSNP:527418737
2317 2317 c, t dbSNP:750431303
2350 2350 a, g dbSNP:775951674
2359 2359 a, g dbSNP:191594904
2394 2394 a, g dbSNP:3024907
2431 2431 a, g dbSNP:148090220
2432 2432 c, t dbSNP:113109887
2442 2442 c, t dbSNP:574975927
2478 2478 a, t dbSNP:2280236
2487 2487 a, c dbSNP:770091061
2516 2516 c, t dbSNP:753311752

Target ORF information:

RefSeq Version XM_006712719
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens signal transducer and activator of transcription 4 (STAT4), transcript variant X4, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_006712719

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
ATGTCTCAGT GGAATCAAGT CCAACAGTTA GAAATCAAGT TTTTGGAGCA GGTGGATCAA 
TTCTATGATG ACAACTTTCC CATGGAAATT CGGCATCTGT TGGCCCAATG GATTGAAAAT
CAAGACTGGG AGGCAGCTTC TAACAATGAA ACCATGGCAA CGATTCTTCT TCAAAACTTG
TTAATACAAC TGGATGAACA GTTAGGTCGT GTTTCCAAAG AGAAAAACCT ACTCTTGATA
CACAATCTAA AAAGAATTAG GAAGGTCCTT CAGGGAAAAT TTCATGGAAA TCCAATGCAT
GTAGCTGTGG TTATTTCAAA CTGTTTAAGG GAAGAGAGGA GAATATTGGC TGCAGCCAAC
ATGCCTGTCC AGGGGCCTCT AGAGAAATCC TTACAAAGTT CTTCAGTTTC AGAAAGACAG
AGGAATGTGG AGCACAAAGT GGCTGCCATT AAAAACAGTG TGCAGATGAC AGAACAAGAT
ACCAAATACT TAGAAGATCT GCAAGACGAA TTTGACTACA GGTATAAAAC AATTCAGACA
ATGGATCAGA GTGACAAGAA TAGTGCCATG GTGAATCAGG AAGTTTTGAC ACTGCAGGAA
ATGCTTAACA GCCTCGATTT CAAGAGAAAG GAGGCTCTCA GTAAAATGAC CCAAATCATC
CATGAGACAG ACCTGTTAAT GAACACCATG CTCATAGAAG AGCTGCAAGA CTGGAAGCGG
CGGCAGCAAA TCGCCTGCAT CGGGGGTCCA CTCCACAATG GGCTCGACCA GCTTCAGAAC
TGCTTTACAC TATTGGCAGA AAGTCTTTTC CAACTGAGAA GGCAATTGGA GAAACTAGAG
GAGCAATCTA CCAAAATGAC ATATGAAGGT GATCCCATTC CAATGCAAAG AACTCACATG
CTAGAAAGAG TCACCTTCTT GATCTACAAC CTTTTCAAGA ACTCATTTGT GGTTGAGCGA
CAGCCATGTA TGCCAACCCA CCCTCAGAGG CCGTTGGTAC TTAAAACCCT AATTCAGTTC
ACTGTAAAAC TAAGGCTACT AATAAAATTG CCAGAACTAA ACTATCAGGT AAAGGTTAAG
GCATCAATTG ACAAGAATGT TTCAACTCTA AGCAACCGAA GATTTGTACT TTGTGGAACT
AATGTCAAAG CCATGTCTAT TGAAGAATCT TCCAATGGGA GTCTCTCAGT AGAATTTCGA
CATTTGCAAC CAAAGGAAAT GAAGTCCAGT GCTGGAGGTA AAGGAAATGA GGGCTGTCAC
ATGGTGACTG AAGAACTTCA TTCCATAACG TTTGAAACAC AGATCTGCCT CTATGGCCTG
ACCATAGATT TGGAGACCAG CTCATTGCCT GTGGTGATGA TTTCCAATGT CAGTCAGTTA
CCTAATGCTT GGGCATCCAT CATTTGGTAC AACGTGTCAA CCAACGATTC CCAGAACTTG
GTTTTCTTTA ATAATCCTCC ACCTGCCACA TTGAGTCAAC TACTGGAGGT GATGAGCTGG
CAGTTTTCAT CGTACGTTGG TCGTGGTCTT AACTCAGATC AACTCCATAT GCTGGCAGAG
AAGCTTACAG TCCAATCTAG CTACAGTGAT GGTCACCTCA CCTGGGCCAA GTTCTGCAAG
GAACATTTAC CTGGTAAATC ATTTACCTTT TGGACATGGC TTGAAGCAAT ATTGGATCTA
ATTAAGAAAC ACATTCTTCC CCTTTGGATT GATGGGTATG TCATGGGCTT TGTTAGCAAA
GAGAAGGAAC GGCTGTTGCT AAAGGATAAA ATGCCTGGCA CCTTTTTATT AAGATTCAGT
GAAAGCCATC TCGGAGGAAT AACTTTCACC TGGGTGGACC ATTCTGAAAG TGGGGAAGTG
AGATTCCACT CTGTAGAACC CTACAATAAA GGCCGGTTGT CTGCTCTGCC ATTCGCTGAC
ATCCTGCGAG ACTACAAAGT TATTATGGCT GAAAACATTC CTGAAAACCC TCTGAAGTAC
CTATATCCTG ACATTCCCAA AGACAAAGCC TTCGGTAAAC ACTACAGCTC TCAGCCTTGC
GAAGTTTCAA GACCAACAGA AAGGGGTGAC AAAGGTTATG TTCCTTCTGT TTTTATCCCC
ATCTCAACAA TCCGAAGTGA TTCAACAGAG CCACATTCTC CATCAGACCT TCTTCCCATG
TCTCCAAGTG TGTATGCGGT GTTGAGAGAA AACCTGAGTC CCACAACAAT TGAAACTGCA
ATGAAGTCTC CTTATTCTGC TGAATGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu60771
Accession Version XM_011511706.1
Sequence Information ORF Nucleotide Sequence (Length: 1530bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product signal transducer and activator of transcription 4 isoform X3
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_005403.18) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
ATGAAGTGGG GCAGCTATTT GTCCATCATG TCTCAGTGGA ATCAAGTCCA ACAGTTAGAA 
ATCAAGTTTT TGGAGCAGGT GGATCAATTC TATGATGACA ACTTTCCCAT GGAAATTCGG
CATCTGTTGG CCCAATGGAT TGAAAATCAA GACTGGGAGG CAGCTTCTAA CAATGAAACC
ATGGCAACGA TTCTTCTTCA AAACTTGTTA ATACAACTGG ATGAACAGTT AGGTCGTGTT
TCCAAAGAGA AAAACCTACT CTTGATACAC AATCTAAAAA GAATTAGGAA GGTCCTTCAG
GGAAAATTTC ATGGAAATCC AATGCATGTA GCTGTGGTTA TTTCAAACTG TTTAAGGGAA
GAGAGGAGAA TATTGGCTGC AGCCAACATG CCTGTCCAGG GGCCTCTAGA GAAATCCTTA
CAAAGTTCTT CAGTTTCAGA AAGACAGAGG AATGTGGAGC ACAAAGTGGC TGCCATTAAA
AACAGTGTGC AGATGACAGA ACAAGATACC AAATACTTAG AAGATCTGCA AGACGAATTT
GACTACAGGT ATAAAACAAT TCAGACAATG GATCAGAGTG ACAAGAATAG TGCCATGGTG
AATCAGGAAG TTTTGACACT GCAGGAAATG CTTAACAGCC TCGATTTCAA GAGAAAGGAG
GCTCTCAGTA AAATGACCCA AATCATCCAT GAGACAGACC TGTTAATGAA CACCATGCTC
ATAGAAGAGC TGCAAGACTG GAAGCGGCGG CAGCAAATCG CCTGCATCGG GGGTCCACTC
CACAATGGGC TCGACCAGCT TCAGAACTGC TTTACACTAT TGGCAGAAAG TCTTTTCCAA
CTGAGAAGGC AATTGGAGAA ACTAGAGGAG CAATCTACCA AAATGACATA TGAAGGTGAT
CCCATTCCAA TGCAAAGAAC TCACATGCTA GAAAGAGTCA CCTTCTTGAT CTACAACCTT
TTCAAGAACT CATTTGTGGT TGAGCGACAG CCATGTATGC CAACCCACCC TCAGAGGCCG
TTGGTACTTA AAACCCTAAT TCAGTTCACT GTAAAACTAA GGCTACTAAT AAAATTGCCA
GAACTAAACT ATCAGGTAAA GGTTAAGGCA TCAATTGACA AGAATGTTTC AACTCTAAGC
AACCGAAGAT TTGTACTTTG TGGAACTAAT GTCAAAGCCA TGTCTATTGA AGAATCTTCC
AATGGGAGTC TCTCAGTAGA ATTTCGACAT TTGCAACCAA AGGAAATGAA GTCCAGTGCT
GGAGGTAAAG GAAATGAGGG CTGTCACATG GTGACTGAAG AACTTCATTC CATAACGTTT
GAAACACAGA TCTGCCTCTA TGGCCTGACC ATAGATTTGG AGACCAGCTC ATTGCCTGTG
GTGATGATTT CCAATGTCAG TCAGTTACCT AATGCTTGGG CATCCATCAT TTGGTACAAC
GTGTCAACCA ACGATTCCCA GGGTCTGGTC AGCTGCCAAC TATGTGCGTA CCAGAGAGTT
CCAGGGCCAT CCTATGACTC TGTTAACTAA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqXP_011510008.1
CDS164..1693
Misc Feature(1)194..553(+)
Misc Feature(2)599..1132(+)
Misc Feature(3)1136..>1633(+)
Translation
Position Chain Variation Link
4 4 c, g dbSNP:570762403
25 25 a, g dbSNP:563408234
86 86 a, t dbSNP:559402424
101 101 c, g dbSNP:765581076
137 137 a, g dbSNP:541906168
146 146 a, g dbSNP:574621309
210 210 c, t dbSNP:778760914
226 226 a, c dbSNP:754787268
232 232 c, t dbSNP:753587179
286 286 g, t dbSNP:766134008
295 295 a, c dbSNP:760427388
298 298 a, g dbSNP:750034868
304 304 c, t dbSNP:35500382
315 315 a, g dbSNP:761161672
325 325 a, g dbSNP:756950986
351 351 c, t dbSNP:750095435
373 373 a, g dbSNP:767019947
392 392 -, ttag dbSNP:766324016
397 397 a, t dbSNP:369256225
399 399 g, t dbSNP:751076320
405 405 c, t dbSNP:267599129
407 407 a, g dbSNP:763673195
425 425 c, t dbSNP:760176547
435 435 a, g dbSNP:777271668
439 439 a, g dbSNP:546810787
450 450 a, g dbSNP:202184860
462 462 a, g dbSNP:773503051
473 473 c, t dbSNP:757999757
485 485 a, g dbSNP:752105122
492 492 c, t dbSNP:778453112
500 500 a, g dbSNP:756625612
508 508 a, g dbSNP:3024838
514 514 c, t dbSNP:560856047
523 523 a, g dbSNP:762103216
533 533 a, g dbSNP:3024839
542 542 a, g dbSNP:372012413
548 548 a, g dbSNP:763055396
550 550 c, t dbSNP:775474969
564 564 a, g dbSNP:773188982
565 565 a, g dbSNP:771977877
573 573 a, t dbSNP:140675301
580 580 c, t dbSNP:145071895
581 581 c, t dbSNP:768064931
617 617 a, g, t dbSNP:370819441
622 622 a, g dbSNP:757804856
632 632 c, g dbSNP:747495835
636 636 c, t dbSNP:778170459
642 642 c, t dbSNP:551175992
650 650 a, g dbSNP:758720903
657 657 c, t dbSNP:376677137
659 659 a, g dbSNP:372399682
672 672 c, t dbSNP:775033600
679 679 -, ctta dbSNP:779446409
694 694 a, g dbSNP:35918099
697 697 c, t dbSNP:199940585
710 710 a, g dbSNP:778192508
719 719 a, g dbSNP:758709109
721 721 a, g dbSNP:748501058
733 733 c, g dbSNP:779115246
740 740 a, g dbSNP:757114207
749 749 a, t dbSNP:769304507
760 760 c, g dbSNP:543324204
793 793 a, g dbSNP:773619472
796 796 a, t dbSNP:74378111
802 802 a, c dbSNP:144713478
805 805 c, g dbSNP:753599408
820 820 a, g dbSNP:367890072
824 824 a, g dbSNP:757165202
830 830 a, g dbSNP:145218540
840 840 c, t dbSNP:778253892
844 844 a, g dbSNP:139598810
845 845 a, g dbSNP:749622712
852 852 a, g dbSNP:780454944
870 870 c, t dbSNP:770181391
880 880 a, g dbSNP:746059460
881 881 a, c dbSNP:781395541
883 883 c, t dbSNP:757282952
885 885 c, t dbSNP:746974489
886 886 a, g dbSNP:371181176
890 890 a, g dbSNP:758217844
909 909 a, g dbSNP:61756200
912 912 a, g dbSNP:764990697
922 922 c, t dbSNP:557179689
923 923 a, g, t dbSNP:201972198
924 924 c, t dbSNP:760044145
931 931 c, t dbSNP:189939340
932 932 a, g dbSNP:764656850
940 940 a, g dbSNP:763524392
945 945 a, g dbSNP:776049747
948 948 a, g dbSNP:770273474
952 952 c, g dbSNP:746170953
955 955 c, t dbSNP:138111228
956 956 a, g dbSNP:771061948
968 968 a, g dbSNP:113436186
970 970 c, t dbSNP:747018092
982 982 a, c dbSNP:776940641
984 984 c, t dbSNP:779542390
995 995 a, c dbSNP:35279173
997 997 c, t dbSNP:747228179
1003 1003 a, g, t dbSNP:571829920
1006 1006 a, g dbSNP:140221173
1007 1007 a, g dbSNP:748082505
1008 1008 a, g dbSNP:778762924
1015 1015 a, g dbSNP:768517793
1024 1024 a, g dbSNP:748998598
1028 1028 a, g dbSNP:142125913
1030 1030 a, g dbSNP:532043947
1036 1036 a, g dbSNP:755772067
1041 1041 c, t dbSNP:750090759
1048 1048 c, g dbSNP:780920887
1054 1054 c, t dbSNP:138535661
1066 1066 c, t dbSNP:374707313
1071 1071 c, t dbSNP:765796756
1074 1074 a, t dbSNP:760055169
1079 1079 a, g dbSNP:754199351
1083 1083 c, t dbSNP:200982266
1109 1109 c, t dbSNP:760872742
1111 1111 c, g dbSNP:548245892
1112 1112 a, g dbSNP:772150342
1113 1113 g, t dbSNP:761830960
1120 1120 c, t dbSNP:140970138
1121 1121 c, g, t dbSNP:749227253
1124 1124 g, t dbSNP:779772586
1144 1144 a, t dbSNP:774465481
1149 1149 a, g dbSNP:143642103
1156 1156 a, g dbSNP:762868543
1160 1160 a, g dbSNP:775435376
1162 1162 a, g dbSNP:769491603
1171 1171 c, t dbSNP:745613218
1183 1183 a, g dbSNP:559315611
1196 1196 a, t dbSNP:770753645
1211 1211 a, t dbSNP:746642521
1215 1215 c, t dbSNP:777211622
1220 1220 c, g dbSNP:757857474
1243 1243 a, c dbSNP:181250926
1259 1259 a, g dbSNP:757553644
1271 1271 a, g dbSNP:751746803
1278 1278 c, t dbSNP:764332457
1289 1289 c, g dbSNP:777972042
1307 1307 c, t dbSNP:768169551
1315 1315 -, t dbSNP:763732068
1315 1315 a, t dbSNP:750700455
1317 1317 c, t dbSNP:762403752
1327 1327 a, t dbSNP:777158012
1335 1335 c, t dbSNP:771471597
1345 1345 a, g dbSNP:376043190
1349 1349 a, g dbSNP:368876096
1368 1368 c, g dbSNP:199633613
1384 1384 a, g dbSNP:772256750
1398 1398 a, t dbSNP:775033790
1400 1400 c, t dbSNP:764645584
1401 1401 c, t dbSNP:200636478
1420 1420 c, t dbSNP:773531490
1428 1428 c, g dbSNP:772506095
1474 1474 c, t dbSNP:201192423
1476 1476 c, t dbSNP:763858532
1479 1479 c, t dbSNP:758109437
1480 1480 a, g dbSNP:145312304
1514 1514 a, g dbSNP:764815073
1527 1527 c, t dbSNP:141331848
1528 1528 a, c dbSNP:144421302
1531 1531 a, c dbSNP:530278225
1538 1538 c, g dbSNP:544508292
1558 1558 c, t dbSNP:778632183
1582 1582 a, g dbSNP:762476453
1588 1588 c, t dbSNP:200929981
1603 1603 c, t dbSNP:142491497
1614 1614 a, g, t dbSNP:146386562
1615 1615 c, t dbSNP:769952683
1616 1616 a, g dbSNP:759785386
1647 1647 a, g dbSNP:538413385
1651 1651 g, t dbSNP:755570184
1662 1662 c, t dbSNP:548718417
1719 1719 a, g dbSNP:536841663
1722 1722 c, t dbSNP:577769452
1749 1749 c, t dbSNP:752182576

Target ORF information:

RefSeq Version XM_011511706
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens signal transducer and activator of transcription 4 (STAT4), transcript variant X5, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011511706

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
ATGAAGTGGG GCAGCTATTT GTCCATCATG TCTCAGTGGA ATCAAGTCCA ACAGTTAGAA 
ATCAAGTTTT TGGAGCAGGT GGATCAATTC TATGATGACA ACTTTCCCAT GGAAATTCGG
CATCTGTTGG CCCAATGGAT TGAAAATCAA GACTGGGAGG CAGCTTCTAA CAATGAAACC
ATGGCAACGA TTCTTCTTCA AAACTTGTTA ATACAACTGG ATGAACAGTT AGGTCGTGTT
TCCAAAGAGA AAAACCTACT CTTGATACAC AATCTAAAAA GAATTAGGAA GGTCCTTCAG
GGAAAATTTC ATGGAAATCC AATGCATGTA GCTGTGGTTA TTTCAAACTG TTTAAGGGAA
GAGAGGAGAA TATTGGCTGC AGCCAACATG CCTGTCCAGG GGCCTCTAGA GAAATCCTTA
CAAAGTTCTT CAGTTTCAGA AAGACAGAGG AATGTGGAGC ACAAAGTGGC TGCCATTAAA
AACAGTGTGC AGATGACAGA ACAAGATACC AAATACTTAG AAGATCTGCA AGACGAATTT
GACTACAGGT ATAAAACAAT TCAGACAATG GATCAGAGTG ACAAGAATAG TGCCATGGTG
AATCAGGAAG TTTTGACACT GCAGGAAATG CTTAACAGCC TCGATTTCAA GAGAAAGGAG
GCTCTCAGTA AAATGACCCA AATCATCCAT GAGACAGACC TGTTAATGAA CACCATGCTC
ATAGAAGAGC TGCAAGACTG GAAGCGGCGG CAGCAAATCG CCTGCATCGG GGGTCCACTC
CACAATGGGC TCGACCAGCT TCAGAACTGC TTTACACTAT TGGCAGAAAG TCTTTTCCAA
CTGAGAAGGC AATTGGAGAA ACTAGAGGAG CAATCTACCA AAATGACATA TGAAGGTGAT
CCCATTCCAA TGCAAAGAAC TCACATGCTA GAAAGAGTCA CCTTCTTGAT CTACAACCTT
TTCAAGAACT CATTTGTGGT TGAGCGACAG CCATGTATGC CAACCCACCC TCAGAGGCCG
TTGGTACTTA AAACCCTAAT TCAGTTCACT GTAAAACTAA GGCTACTAAT AAAATTGCCA
GAACTAAACT ATCAGGTAAA GGTTAAGGCA TCAATTGACA AGAATGTTTC AACTCTAAGC
AACCGAAGAT TTGTACTTTG TGGAACTAAT GTCAAAGCCA TGTCTATTGA AGAATCTTCC
AATGGGAGTC TCTCAGTAGA ATTTCGACAT TTGCAACCAA AGGAAATGAA GTCCAGTGCT
GGAGGTAAAG GAAATGAGGG CTGTCACATG GTGACTGAAG AACTTCATTC CATAACGTTT
GAAACACAGA TCTGCCTCTA TGGCCTGACC ATAGATTTGG AGACCAGCTC ATTGCCTGTG
GTGATGATTT CCAATGTCAG TCAGTTACCT AATGCTTGGG CATCCATCAT TTGGTACAAC
GTGTCAACCA ACGATTCCCA GGGTCTGGTC AGCTGCCAAC TATGTGCGTA CCAGAGAGTT
CCAGGGCCAT CCTATGACTC TGTTAACTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu18290
Accession Version NM_001243835.1
Sequence Information ORF Nucleotide Sequence (Length: 2247bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 27-MAR-2015
Organism Homo sapiens (human)
Product signal transducer and activator of transcription 4
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC399230.1 and BC031212.1. Summary: The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Aug 2011]. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC031212.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
ATGTCTCAGT GGAATCAAGT CCAACAGTTA GAAATCAAGT TTTTGGAGCA GGTGGATCAA 
TTCTATGATG ACAACTTTCC CATGGAAATT CGGCATCTGT TGGCCCAATG GATTGAAAAT
CAAGACTGGG AGGCAGCTTC TAACAATGAA ACCATGGCAA CGATTCTTCT TCAAAACTTG
TTAATACAAC TGGATGAACA GTTAGGTCGT GTTTCCAAAG AGAAAAACCT ACTCTTGATA
CACAATCTAA AAAGAATTAG GAAGGTCCTT CAGGGAAAAT TTCATGGAAA TCCAATGCAT
GTAGCTGTGG TTATTTCAAA CTGTTTAAGG GAAGAGAGGA GAATATTGGC TGCAGCCAAC
ATGCCTGTCC AGGGGCCTCT AGAGAAATCC TTACAAAGTT CTTCAGTTTC AGAAAGACAG
AGGAATGTGG AGCACAAAGT GGCTGCCATT AAAAACAGTG TGCAGATGAC AGAACAAGAT
ACCAAATACT TAGAAGATCT GCAAGACGAA TTTGACTACA GGTATAAAAC AATTCAGACA
ATGGATCAGA GTGACAAGAA TAGTGCCATG GTGAATCAGG AAGTTTTGAC ACTGCAGGAA
ATGCTTAACA GCCTCGATTT CAAGAGAAAG GAGGCTCTCA GTAAAATGAC CCAAATCATC
CATGAGACAG ACCTGTTAAT GAACACCATG CTCATAGAAG AGCTGCAAGA CTGGAAGCGG
CGGCAGCAAA TCGCCTGCAT CGGGGGTCCA CTCCACAATG GGCTCGACCA GCTTCAGAAC
TGCTTTACAC TATTGGCAGA AAGTCTTTTC CAACTGAGAA GGCAATTGGA GAAACTAGAG
GAGCAATCTA CCAAAATGAC ATATGAAGGT GATCCCATTC CAATGCAAAG AACTCACATG
CTAGAAAGAG TCACCTTCTT GATCTACAAC CTTTTCAAGA ACTCATTTGT GGTTGAGCGA
CAGCCATGTA TGCCAACCCA CCCTCAGAGG CCGTTGGTAC TTAAAACCCT AATTCAGTTC
ACTGTAAAAC TAAGGCTACT AATAAAATTG CCAGAACTAA ACTATCAGGT AAAGGTTAAG
GCATCAATTG ACAAGAATGT TTCAACTCTA AGCAACCGAA GATTTGTACT TTGTGGAACT
AATGTCAAAG CCATGTCTAT TGAAGAATCT TCCAATGGGA GTCTCTCAGT AGAATTTCGA
CATTTGCAAC CAAAGGAAAT GAAGTCCAGT GCTGGAGGTA AAGGAAATGA GGGCTGTCAC
ATGGTGACTG AAGAACTTCA TTCCATAACG TTTGAAACAC AGATCTGCCT CTATGGCCTG
ACCATAGATT TGGAGACCAG CTCATTGCCT GTGGTGATGA TTTCCAATGT CAGTCAGTTA
CCTAATGCTT GGGCATCCAT CATTTGGTAC AACGTGTCAA CCAACGATTC CCAGAACTTG
GTTTTCTTTA ATAATCCTCC ACCTGCCACA TTGAGTCAAC TACTGGAGGT GATGAGCTGG
CAGTTTTCAT CGTACGTTGG TCGTGGTCTT AACTCAGATC AACTCCATAT GCTGGCAGAG
AAGCTTACAG TCCAATCTAG CTACAGTGAT GGTCACCTCA CCTGGGCCAA GTTCTGCAAG
GAACATTTAC CTGGTAAATC ATTTACCTTT TGGACATGGC TTGAAGCAAT ATTGGATCTA
ATTAAGAAAC ACATTCTTCC CCTTTGGATT GATGGGTATG TCATGGGCTT TGTTAGCAAA
GAGAAGGAAC GGCTGTTGCT AAAGGATAAA ATGCCTGGCA CCTTTTTATT AAGATTCAGT
GAAAGCCATC TCGGAGGAAT AACTTTCACC TGGGTGGACC ATTCTGAAAG TGGGGAAGTG
AGATTCCACT CTGTAGAACC CTACAATAAA GGCCGGTTGT CTGCTCTGCC ATTCGCTGAC
ATCCTGCGAG ACTACAAAGT TATTATGGCT GAAAACATTC CTGAAAACCC TCTGAAGTAC
CTATATCCTG ACATTCCCAA AGACAAAGCC TTCGGTAAAC ACTACAGCTC TCAGCCTTGC
GAAGTTTCAA GACCAACAGA AAGGGGTGAC AAAGGTTATG TTCCTTCTGT TTTTATCCCC
ATCTCAACAA TCCGAAGTGA TTCAACAGAG CCACATTCTC CATCAGACCT TCTTCCCATG
TCTCCAAGTG TGTATGCGGT GTTGAGAGAA AACCTGAGTC CCACAACAAT TGAAACTGCA
ATGAAGTCTC CTTATTCTGC TGAATGA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_001230764.1
CDS265..2511
Misc Feature(1)166..168(+)
Misc Feature(2)268..627(+)
Misc Feature(3)673..1206(+)
Misc Feature(4)1210..1953(+)
Misc Feature(5)1921..2364(+)
Misc Feature(6)2002..2142(+)
Misc Feature(7)2137..2187(+)
Misc Feature(8)2167..2358(+)
Misc Feature(9)2341..2343(+)
Exon (1)1..263
Gene:STAT4
Gene Synonym:
Exon (2)264..392
Gene:STAT4
Gene Synonym:
Exon (3)393..537
Gene:STAT4
Gene Synonym:
Exon (4)538..636
Gene:STAT4
Gene Synonym:
Exon (5)637..729
Gene:STAT4
Gene Synonym:
Exon (6)730..808
Gene:STAT4
Gene Synonym:
Exon (7)809..894
Gene:STAT4
Gene Synonym:
Exon (8)895..1046
Gene:STAT4
Gene Synonym:
Exon (9)1047..1205
Gene:STAT4
Gene Synonym:
Exon (10)1206..1298
Gene:STAT4
Gene Synonym:
Exon (11)1299..1358
Gene:STAT4
Gene Synonym:
Exon (12)1359..1376
Gene:STAT4
Gene Synonym:
Exon (13)1377..1470
Gene:STAT4
Gene Synonym:
Exon (14)1471..1515
Gene:STAT4
Gene Synonym:
Exon (15)1516..1599
Gene:STAT4
Gene Synonym:
Exon (16)1600..1698
Gene:STAT4
Gene Synonym:
Exon (17)1699..1834
Gene:STAT4
Gene Synonym:
Exon (18)1835..1884
Gene:STAT4
Gene Synonym:
Exon (19)1885..1979
Gene:STAT4
Gene Synonym:
Exon (20)1980..2116
Gene:STAT4
Gene Synonym:
Exon (21)2117..2308
Gene:STAT4
Gene Synonym:
Exon (22)2309..2375
Gene:STAT4
Gene Synonym:
Exon (23)2376..2484
Gene:STAT4
Gene Synonym:
Exon (24)2485..2775
Gene:STAT4
Gene Synonym:
Translation
Position Chain Variation Link
14 14 c, t dbSNP:577074531
56 56 c, t dbSNP:750900735
69 69 c, t dbSNP:116304492
81 81 c, t dbSNP:543466196
97 97 g, t dbSNP:116071025
125 125 a, g dbSNP:184318948
153 153 a, g dbSNP:113656100
201 201 a, g dbSNP:566266647
213 213 g, t dbSNP:190324596
228 228 a, g dbSNP:765694346
236 236 a, g dbSNP:762191212
240 240 a, g dbSNP:539272812
257 257 a, g dbSNP:576914834
284 284 c, t dbSNP:778760914
300 300 a, c dbSNP:754787268
306 306 c, t dbSNP:753587179
360 360 g, t dbSNP:766134008
369 369 a, c dbSNP:760427388
372 372 a, g dbSNP:750034868
378 378 c, t dbSNP:35500382
389 389 a, g dbSNP:761161672
399 399 a, g dbSNP:756950986
425 425 c, t dbSNP:750095435
447 447 a, g dbSNP:767019947
466 466 -, ttag dbSNP:766324016
471 471 a, t dbSNP:369256225
473 473 g, t dbSNP:751076320
479 479 c, t dbSNP:267599129
481 481 a, g dbSNP:763673195
499 499 c, t dbSNP:760176547
509 509 a, g dbSNP:777271668
513 513 a, g dbSNP:546810787
524 524 a, g dbSNP:202184860
536 536 a, g dbSNP:773503051
547 547 c, t dbSNP:757999757
559 559 a, g dbSNP:752105122
566 566 c, t dbSNP:778453112
574 574 a, g dbSNP:756625612
582 582 a, g dbSNP:3024838
588 588 c, t dbSNP:560856047
597 597 a, g dbSNP:762103216
607 607 a, g dbSNP:3024839
616 616 a, g dbSNP:372012413
622 622 a, g dbSNP:763055396
624 624 c, t dbSNP:775474969
638 638 a, g dbSNP:773188982
639 639 a, g dbSNP:771977877
647 647 a, t dbSNP:140675301
654 654 c, t dbSNP:145071895
655 655 c, t dbSNP:768064931
691 691 a, g, t dbSNP:370819441
696 696 a, g dbSNP:757804856
706 706 c, g dbSNP:747495835
710 710 c, t dbSNP:778170459
716 716 c, t dbSNP:551175992
724 724 a, g dbSNP:758720903
731 731 c, t dbSNP:376677137
733 733 a, g dbSNP:372399682
746 746 c, t dbSNP:775033600
753 753 -, ctta dbSNP:779446409
768 768 a, g dbSNP:35918099
771 771 c, t dbSNP:199940585
784 784 a, g dbSNP:778192508
793 793 a, g dbSNP:758709109
795 795 a, g dbSNP:748501058
807 807 c, g dbSNP:779115246
814 814 a, g dbSNP:757114207
823 823 a, t dbSNP:769304507
834 834 c, g dbSNP:543324204
867 867 a, g dbSNP:773619472
870 870 a, t dbSNP:74378111
876 876 a, c dbSNP:144713478
879 879 c, g dbSNP:753599408
894 894 a, g dbSNP:367890072
898 898 a, g dbSNP:757165202
904 904 a, g dbSNP:145218540
914 914 c, t dbSNP:778253892
918 918 a, g dbSNP:139598810
919 919 a, g dbSNP:749622712
926 926 a, g dbSNP:780454944
944 944 c, t dbSNP:770181391
954 954 a, g dbSNP:746059460
955 955 a, c dbSNP:781395541
957 957 c, t dbSNP:757282952
959 959 c, t dbSNP:746974489
960 960 a, g dbSNP:371181176
964 964 a, g dbSNP:758217844
983 983 a, g dbSNP:61756200
986 986 a, g dbSNP:764990697
996 996 c, t dbSNP:557179689
997 997 a, g, t dbSNP:201972198
998 998 c, t dbSNP:760044145
1005 1005 c, t dbSNP:189939340
1006 1006 a, g dbSNP:764656850
1014 1014 a, g dbSNP:763524392
1019 1019 a, g dbSNP:776049747
1022 1022 a, g dbSNP:770273474
1026 1026 c, g dbSNP:746170953
1029 1029 c, t dbSNP:138111228
1030 1030 a, g dbSNP:771061948
1042 1042 a, g dbSNP:113436186
1044 1044 c, t dbSNP:747018092
1056 1056 a, c dbSNP:776940641
1058 1058 c, t dbSNP:779542390
1069 1069 a, c dbSNP:35279173
1071 1071 c, t dbSNP:747228179
1077 1077 a, g, t dbSNP:571829920
1080 1080 a, g dbSNP:140221173
1081 1081 a, g dbSNP:748082505
1082 1082 a, g dbSNP:778762924
1089 1089 a, g dbSNP:768517793
1098 1098 a, g dbSNP:748998598
1102 1102 a, g dbSNP:142125913
1104 1104 a, g dbSNP:532043947
1110 1110 a, g dbSNP:755772067
1115 1115 c, t dbSNP:750090759
1122 1122 c, g dbSNP:780920887
1128 1128 c, t dbSNP:138535661
1140 1140 c, t dbSNP:374707313
1145 1145 c, t dbSNP:765796756
1148 1148 a, t dbSNP:760055169
1153 1153 a, g dbSNP:754199351
1157 1157 c, t dbSNP:200982266
1183 1183 c, t dbSNP:760872742
1185 1185 c, g dbSNP:548245892
1186 1186 a, g dbSNP:772150342
1187 1187 g, t dbSNP:761830960
1194 1194 c, t dbSNP:140970138
1195 1195 c, g, t dbSNP:749227253
1198 1198 g, t dbSNP:779772586
1218 1218 a, t dbSNP:774465481
1223 1223 a, g dbSNP:143642103
1230 1230 a, g dbSNP:762868543
1234 1234 a, g dbSNP:775435376
1236 1236 a, g dbSNP:769491603
1245 1245 c, t dbSNP:745613218
1257 1257 a, g dbSNP:559315611
1270 1270 a, t dbSNP:770753645
1285 1285 a, t dbSNP:746642521
1289 1289 c, t dbSNP:777211622
1294 1294 c, g dbSNP:757857474
1317 1317 a, c dbSNP:181250926
1333 1333 a, g dbSNP:757553644
1345 1345 a, g dbSNP:751746803
1352 1352 c, t dbSNP:764332457
1363 1363 c, g dbSNP:777972042
1381 1381 c, t dbSNP:768169551
1389 1389 -, t dbSNP:763732068
1389 1389 a, t dbSNP:750700455
1391 1391 c, t dbSNP:762403752
1401 1401 a, t dbSNP:777158012
1409 1409 c, t dbSNP:771471597
1419 1419 a, g dbSNP:376043190
1423 1423 a, g dbSNP:368876096
1442 1442 c, g dbSNP:199633613
1458 1458 a, g dbSNP:772256750
1472 1472 a, t dbSNP:775033790
1474 1474 c, t dbSNP:764645584
1475 1475 c, t dbSNP:200636478
1494 1494 c, t dbSNP:773531490
1502 1502 c, g dbSNP:772506095
1548 1548 c, t dbSNP:201192423
1550 1550 c, t dbSNP:763858532
1553 1553 c, t dbSNP:758109437
1554 1554 a, g dbSNP:145312304
1588 1588 a, g dbSNP:764815073
1601 1601 c, t dbSNP:141331848
1602 1602 a, c dbSNP:144421302
1605 1605 a, c dbSNP:530278225
1612 1612 c, g dbSNP:544508292
1632 1632 c, t dbSNP:778632183
1656 1656 a, g dbSNP:762476453
1662 1662 c, t dbSNP:200929981
1677 1677 c, t dbSNP:142491497
1688 1688 a, g, t dbSNP:146386562
1689 1689 c, t dbSNP:769952683
1690 1690 a, g dbSNP:759785386
1699 1699 a, c dbSNP:765625619
1701 1701 c, t dbSNP:138956189
1705 1705 a, g dbSNP:769270663
1718 1718 a, c dbSNP:771017653
1719 1719 c, t dbSNP:760702751
1722 1722 c, t dbSNP:79347691
1725 1725 a, c dbSNP:77509921
1735 1735 c, t dbSNP:373669618
1737 1737 g, t dbSNP:149621054
1740 1740 c, t dbSNP:138191914
1747 1747 c, t dbSNP:748906866
1776 1776 a, g dbSNP:201470036
1779 1779 c, t dbSNP:139085875
1780 1780 a, g dbSNP:749994944
1786 1786 c, t dbSNP:780829180
1787 1787 a, g dbSNP:376947712
1802 1802 a, t dbSNP:147007636
1813 1813 a, g, t dbSNP:755317297
1848 1848 c, t dbSNP:768445696
1850 1850 a, g dbSNP:760335389
1860 1860 c, t dbSNP:147850919
1861 1861 c, t dbSNP:767596903
1870 1870 a, g dbSNP:761904937
1880 1880 a, g dbSNP:774187563
1888 1888 c, t dbSNP:765178000
1904 1904 c, t dbSNP:144091208
1905 1905 a, g dbSNP:759378650
1912 1912 c, t dbSNP:373191999
1916 1916 a, g dbSNP:776531286
1959 1959 c, t dbSNP:770642587
1961 1961 g, t dbSNP:760189410
1965 1965 c, t dbSNP:540628434
1992 1992 c, t dbSNP:760443863
2014 2014 c, t dbSNP:3024933
2015 2015 a, g, t dbSNP:779069171
2020 2020 g, t dbSNP:199609035
2037 2037 a, g dbSNP:761281261
2038 2038 c, g dbSNP:773810325
2054 2054 c, t dbSNP:770306554
2070 2070 c, g dbSNP:201150110
2076 2076 c, t dbSNP:781621586
2077 2077 a, g dbSNP:771192197
2079 2079 a, g dbSNP:747310117
2114 2114 c, g dbSNP:777832373
2117 2117 c, g dbSNP:776987023
2125 2125 a, c dbSNP:771372502
2145 2145 c, g dbSNP:747300394
2159 2159 a, g dbSNP:149089413
2160 2160 g, t dbSNP:112819248
2178 2178 a, c, t dbSNP:369720896
2179 2179 g, t dbSNP:755096256
2191 2191 a, c dbSNP:759048381
2223 2223 g, t dbSNP:749296968
2226 2226 c, t dbSNP:779825681
2234 2234 c, t dbSNP:756037985
2235 2235 a, t dbSNP:750206397
2236 2236 c, t dbSNP:202018151
2247 2247 a, g dbSNP:767240927
2259 2259 c, t dbSNP:756905537
2267 2267 a, g dbSNP:751205891
2277 2277 c, t dbSNP:368134591
2278 2278 a, g dbSNP:762343259
2282 2282 a, g dbSNP:777230968
2293 2293 a, t dbSNP:766821566
2294 2294 c, g dbSNP:761189841
2304 2304 a, c, t dbSNP:368928990
2322 2322 a, c dbSNP:764742090
2326 2326 a, g dbSNP:761155615
2327 2327 a, g dbSNP:371989874
2328 2328 c, g dbSNP:768045385
2333 2333 a, c, g dbSNP:774816816
2352 2352 c, t dbSNP:550869545
2353 2353 g, t dbSNP:768782205
2364 2364 a, c dbSNP:763177887
2373 2373 a, t dbSNP:775435740
2378 2378 a, g dbSNP:370218298
2384 2384 a, g dbSNP:111535990
2389 2389 a, g dbSNP:770874469
2390 2390 a, c dbSNP:746885035
2398 2398 c, t dbSNP:772952207
2399 2399 a, g dbSNP:752431273
2430 2430 a, c dbSNP:781093912
2441 2441 c, t dbSNP:771889653
2442 2442 a, c, g dbSNP:139030621
2457 2457 c, t dbSNP:754637298
2466 2466 a, c dbSNP:748831456
2471 2471 -, caa dbSNP:776683947
2472 2472 a, g dbSNP:779652985
2481 2481 g, t dbSNP:757844095
2495 2495 c, g dbSNP:773968889
2504 2504 c, t dbSNP:768437698
2517 2517 c, t dbSNP:748882692
2519 2519 a, c dbSNP:3024906
2524 2524 c, t dbSNP:373725872
2527 2527 c, t dbSNP:199549890
2528 2528 a, c, g dbSNP:376543078
2529 2529 c, t dbSNP:758789071
2531 2531 c, t dbSNP:373617359
2533 2533 a, g dbSNP:765524533
2540 2540 c, g dbSNP:755264465
2547 2547 a, g dbSNP:778533196
2550 2550 a, g dbSNP:370883796
2556 2556 g, t dbSNP:766497133
2557 2557 g, t dbSNP:527418737
2558 2558 c, t dbSNP:750431303
2591 2591 a, g dbSNP:775951674
2600 2600 a, g dbSNP:191594904
2635 2635 a, g dbSNP:3024907
2672 2672 a, g dbSNP:148090220
2673 2673 c, t dbSNP:113109887
2683 2683 c, t dbSNP:574975927
2719 2719 a, t dbSNP:2280236
2728 2728 a, c dbSNP:770091061
2757 2757 c, t dbSNP:753311752

Target ORF information:

RefSeq Version NM_001243835
Organism Homo sapiens (human)
Definition Homo sapiens signal transducer and activator of transcription 4 (STAT4), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001243835

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
ATGTCTCAGT GGAATCAAGT CCAACAGTTA GAAATCAAGT TTTTGGAGCA GGTGGATCAA 
TTCTATGATG ACAACTTTCC CATGGAAATT CGGCATCTGT TGGCCCAATG GATTGAAAAT
CAAGACTGGG AGGCAGCTTC TAACAATGAA ACCATGGCAA CGATTCTTCT TCAAAACTTG
TTAATACAAC TGGATGAACA GTTAGGTCGT GTTTCCAAAG AGAAAAACCT ACTCTTGATA
CACAATCTAA AAAGAATTAG GAAGGTCCTT CAGGGAAAAT TTCATGGAAA TCCAATGCAT
GTAGCTGTGG TTATTTCAAA CTGTTTAAGG GAAGAGAGGA GAATATTGGC TGCAGCCAAC
ATGCCTGTCC AGGGGCCTCT AGAGAAATCC TTACAAAGTT CTTCAGTTTC AGAAAGACAG
AGGAATGTGG AGCACAAAGT GGCTGCCATT AAAAACAGTG TGCAGATGAC AGAACAAGAT
ACCAAATACT TAGAAGATCT GCAAGACGAA TTTGACTACA GGTATAAAAC AATTCAGACA
ATGGATCAGA GTGACAAGAA TAGTGCCATG GTGAATCAGG AAGTTTTGAC ACTGCAGGAA
ATGCTTAACA GCCTCGATTT CAAGAGAAAG GAGGCTCTCA GTAAAATGAC CCAAATCATC
CATGAGACAG ACCTGTTAAT GAACACCATG CTCATAGAAG AGCTGCAAGA CTGGAAGCGG
CGGCAGCAAA TCGCCTGCAT CGGGGGTCCA CTCCACAATG GGCTCGACCA GCTTCAGAAC
TGCTTTACAC TATTGGCAGA AAGTCTTTTC CAACTGAGAA GGCAATTGGA GAAACTAGAG
GAGCAATCTA CCAAAATGAC ATATGAAGGT GATCCCATTC CAATGCAAAG AACTCACATG
CTAGAAAGAG TCACCTTCTT GATCTACAAC CTTTTCAAGA ACTCATTTGT GGTTGAGCGA
CAGCCATGTA TGCCAACCCA CCCTCAGAGG CCGTTGGTAC TTAAAACCCT AATTCAGTTC
ACTGTAAAAC TAAGGCTACT AATAAAATTG CCAGAACTAA ACTATCAGGT AAAGGTTAAG
GCATCAATTG ACAAGAATGT TTCAACTCTA AGCAACCGAA GATTTGTACT TTGTGGAACT
AATGTCAAAG CCATGTCTAT TGAAGAATCT TCCAATGGGA GTCTCTCAGT AGAATTTCGA
CATTTGCAAC CAAAGGAAAT GAAGTCCAGT GCTGGAGGTA AAGGAAATGA GGGCTGTCAC
ATGGTGACTG AAGAACTTCA TTCCATAACG TTTGAAACAC AGATCTGCCT CTATGGCCTG
ACCATAGATT TGGAGACCAG CTCATTGCCT GTGGTGATGA TTTCCAATGT CAGTCAGTTA
CCTAATGCTT GGGCATCCAT CATTTGGTAC AACGTGTCAA CCAACGATTC CCAGAACTTG
GTTTTCTTTA ATAATCCTCC ACCTGCCACA TTGAGTCAAC TACTGGAGGT GATGAGCTGG
CAGTTTTCAT CGTACGTTGG TCGTGGTCTT AACTCAGATC AACTCCATAT GCTGGCAGAG
AAGCTTACAG TCCAATCTAG CTACAGTGAT GGTCACCTCA CCTGGGCCAA GTTCTGCAAG
GAACATTTAC CTGGTAAATC ATTTACCTTT TGGACATGGC TTGAAGCAAT ATTGGATCTA
ATTAAGAAAC ACATTCTTCC CCTTTGGATT GATGGGTATG TCATGGGCTT TGTTAGCAAA
GAGAAGGAAC GGCTGTTGCT AAAGGATAAA ATGCCTGGCA CCTTTTTATT AAGATTCAGT
GAAAGCCATC TCGGAGGAAT AACTTTCACC TGGGTGGACC ATTCTGAAAG TGGGGAAGTG
AGATTCCACT CTGTAGAACC CTACAATAAA GGCCGGTTGT CTGCTCTGCC ATTCGCTGAC
ATCCTGCGAG ACTACAAAGT TATTATGGCT GAAAACATTC CTGAAAACCC TCTGAAGTAC
CTATATCCTG ACATTCCCAA AGACAAAGCC TTCGGTAAAC ACTACAGCTC TCAGCCTTGC
GAAGTTTCAA GACCAACAGA AAGGGGTGAC AAAGGTTATG TTCCTTCTGT TTTTATCCCC
ATCTCAACAA TCCGAAGTGA TTCAACAGAG CCACATTCTC CATCAGACCT TCTTCCCATG
TCTCCAAGTG TGTATGCGGT GTTGAGAGAA AACCTGAGTC CCACAACAAT TGAAACTGCA
ATGAAGTCTC CTTATTCTGC TGAATGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu18290
Accession Version NM_003151.3
Sequence Information ORF Nucleotide Sequence (Length: 2247bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 27-MAR-2015
Organism Homo sapiens (human)
Product signal transducer and activator of transcription 4
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC306142.1, L78440.1 and BC031212.1. This sequence is a reference standard in the RefSeqGene project. On Aug 31, 2011 this sequence version replaced gi:21618332. Summary: The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Aug 2011]. Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: L78440.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
ATGTCTCAGT GGAATCAAGT CCAACAGTTA GAAATCAAGT TTTTGGAGCA GGTGGATCAA 
TTCTATGATG ACAACTTTCC CATGGAAATT CGGCATCTGT TGGCCCAATG GATTGAAAAT
CAAGACTGGG AGGCAGCTTC TAACAATGAA ACCATGGCAA CGATTCTTCT TCAAAACTTG
TTAATACAAC TGGATGAACA GTTAGGTCGT GTTTCCAAAG AGAAAAACCT ACTCTTGATA
CACAATCTAA AAAGAATTAG GAAGGTCCTT CAGGGAAAAT TTCATGGAAA TCCAATGCAT
GTAGCTGTGG TTATTTCAAA CTGTTTAAGG GAAGAGAGGA GAATATTGGC TGCAGCCAAC
ATGCCTGTCC AGGGGCCTCT AGAGAAATCC TTACAAAGTT CTTCAGTTTC AGAAAGACAG
AGGAATGTGG AGCACAAAGT GGCTGCCATT AAAAACAGTG TGCAGATGAC AGAACAAGAT
ACCAAATACT TAGAAGATCT GCAAGACGAA TTTGACTACA GGTATAAAAC AATTCAGACA
ATGGATCAGA GTGACAAGAA TAGTGCCATG GTGAATCAGG AAGTTTTGAC ACTGCAGGAA
ATGCTTAACA GCCTCGATTT CAAGAGAAAG GAGGCTCTCA GTAAAATGAC CCAAATCATC
CATGAGACAG ACCTGTTAAT GAACACCATG CTCATAGAAG AGCTGCAAGA CTGGAAGCGG
CGGCAGCAAA TCGCCTGCAT CGGGGGTCCA CTCCACAATG GGCTCGACCA GCTTCAGAAC
TGCTTTACAC TATTGGCAGA AAGTCTTTTC CAACTGAGAA GGCAATTGGA GAAACTAGAG
GAGCAATCTA CCAAAATGAC ATATGAAGGT GATCCCATTC CAATGCAAAG AACTCACATG
CTAGAAAGAG TCACCTTCTT GATCTACAAC CTTTTCAAGA ACTCATTTGT GGTTGAGCGA
CAGCCATGTA TGCCAACCCA CCCTCAGAGG CCGTTGGTAC TTAAAACCCT AATTCAGTTC
ACTGTAAAAC TAAGGCTACT AATAAAATTG CCAGAACTAA ACTATCAGGT AAAGGTTAAG
GCATCAATTG ACAAGAATGT TTCAACTCTA AGCAACCGAA GATTTGTACT TTGTGGAACT
AATGTCAAAG CCATGTCTAT TGAAGAATCT TCCAATGGGA GTCTCTCAGT AGAATTTCGA
CATTTGCAAC CAAAGGAAAT GAAGTCCAGT GCTGGAGGTA AAGGAAATGA GGGCTGTCAC
ATGGTGACTG AAGAACTTCA TTCCATAACG TTTGAAACAC AGATCTGCCT CTATGGCCTG
ACCATAGATT TGGAGACCAG CTCATTGCCT GTGGTGATGA TTTCCAATGT CAGTCAGTTA
CCTAATGCTT GGGCATCCAT CATTTGGTAC AACGTGTCAA CCAACGATTC CCAGAACTTG
GTTTTCTTTA ATAATCCTCC ACCTGCCACA TTGAGTCAAC TACTGGAGGT GATGAGCTGG
CAGTTTTCAT CGTACGTTGG TCGTGGTCTT AACTCAGATC AACTCCATAT GCTGGCAGAG
AAGCTTACAG TCCAATCTAG CTACAGTGAT GGTCACCTCA CCTGGGCCAA GTTCTGCAAG
GAACATTTAC CTGGTAAATC ATTTACCTTT TGGACATGGC TTGAAGCAAT ATTGGATCTA
ATTAAGAAAC ACATTCTTCC CCTTTGGATT GATGGGTATG TCATGGGCTT TGTTAGCAAA
GAGAAGGAAC GGCTGTTGCT AAAGGATAAA ATGCCTGGCA CCTTTTTATT AAGATTCAGT
GAAAGCCATC TCGGAGGAAT AACTTTCACC TGGGTGGACC ATTCTGAAAG TGGGGAAGTG
AGATTCCACT CTGTAGAACC CTACAATAAA GGCCGGTTGT CTGCTCTGCC ATTCGCTGAC
ATCCTGCGAG ACTACAAAGT TATTATGGCT GAAAACATTC CTGAAAACCC TCTGAAGTAC
CTATATCCTG ACATTCCCAA AGACAAAGCC TTCGGTAAAC ACTACAGCTC TCAGCCTTGC
GAAGTTTCAA GACCAACAGA AAGGGGTGAC AAAGGTTATG TTCCTTCTGT TTTTATCCCC
ATCTCAACAA TCCGAAGTGA TTCAACAGAG CCACATTCTC CATCAGACCT TCTTCCCATG
TCTCCAAGTG TGTATGCGGT GTTGAGAGAA AACCTGAGTC CCACAACAAT TGAAACTGCA
ATGAAGTCTC CTTATTCTGC TGAATGA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_003142.1
CDS316..2562
Misc Feature(1)301..303(+)
Misc Feature(2)319..678(+)
Misc Feature(3)724..1257(+)
Misc Feature(4)1261..2004(+)
Misc Feature(5)1972..2415(+)
Misc Feature(6)2053..2193(+)
Misc Feature(7)2188..2238(+)
Misc Feature(8)2218..2409(+)
Misc Feature(9)2392..2394(+)
Misc Feature(10)2392..2394(+)
Misc Feature(11)2476..2478(+)
Misc Feature(12)2476..2478(+)
Exon (1)1..314
Gene:STAT4
Gene Synonym:
Exon (2)315..443
Gene:STAT4
Gene Synonym:
Exon (3)444..588
Gene:STAT4
Gene Synonym:
Exon (4)589..687
Gene:STAT4
Gene Synonym:
Exon (5)688..780
Gene:STAT4
Gene Synonym:
Exon (6)781..859
Gene:STAT4
Gene Synonym:
Exon (7)860..945
Gene:STAT4
Gene Synonym:
Exon (8)946..1097
Gene:STAT4
Gene Synonym:
Exon (9)1098..1256
Gene:STAT4
Gene Synonym:
Exon (10)1257..1349
Gene:STAT4
Gene Synonym:
Exon (11)1350..1409
Gene:STAT4
Gene Synonym:
Exon (12)1410..1427
Gene:STAT4
Gene Synonym:
Exon (13)1428..1521
Gene:STAT4
Gene Synonym:
Exon (14)1522..1566
Gene:STAT4
Gene Synonym:
Exon (15)1567..1650
Gene:STAT4
Gene Synonym:
Exon (16)1651..1749
Gene:STAT4
Gene Synonym:
Exon (17)1750..1885
Gene:STAT4
Gene Synonym:
Exon (18)1886..1935
Gene:STAT4
Gene Synonym:
Exon (19)1936..2030
Gene:STAT4
Gene Synonym:
Exon (20)2031..2167
Gene:STAT4
Gene Synonym:
Exon (21)2168..2359
Gene:STAT4
Gene Synonym:
Exon (22)2360..2426
Gene:STAT4
Gene Synonym:
Exon (23)2427..2535
Gene:STAT4
Gene Synonym:
Exon (24)2536..2826
Gene:STAT4
Gene Synonym:
Translation
Position Chain Variation Link
6 6 c, g dbSNP:547879398
24 24 c, t dbSNP:529781712
59 59 a, g dbSNP:2278940
72 72 c, t dbSNP:760807371
73 73 a, g dbSNP:540874455
82 82 g, t dbSNP:751087937
124 124 a, g dbSNP:775684810
294 294 a, c dbSNP:114318317
335 335 c, t dbSNP:778760914
351 351 a, c dbSNP:754787268
357 357 c, t dbSNP:753587179
411 411 g, t dbSNP:766134008
420 420 a, c dbSNP:760427388
423 423 a, g dbSNP:750034868
429 429 c, t dbSNP:35500382
440 440 a, g dbSNP:761161672
450 450 a, g dbSNP:756950986
476 476 c, t dbSNP:750095435
498 498 a, g dbSNP:767019947
517 517 -, ttag dbSNP:766324016
522 522 a, t dbSNP:369256225
524 524 g, t dbSNP:751076320
530 530 c, t dbSNP:267599129
532 532 a, g dbSNP:763673195
550 550 c, t dbSNP:760176547
560 560 a, g dbSNP:777271668
564 564 a, g dbSNP:546810787
575 575 a, g dbSNP:202184860
587 587 a, g dbSNP:773503051
598 598 c, t dbSNP:757999757
610 610 a, g dbSNP:752105122
617 617 c, t dbSNP:778453112
625 625 a, g dbSNP:756625612
633 633 a, g dbSNP:3024838
639 639 c, t dbSNP:560856047
648 648 a, g dbSNP:762103216
658 658 a, g dbSNP:3024839
667 667 a, g dbSNP:372012413
673 673 a, g dbSNP:763055396
675 675 c, t dbSNP:775474969
689 689 a, g dbSNP:773188982
690 690 a, g dbSNP:771977877
698 698 a, t dbSNP:140675301
705 705 c, t dbSNP:145071895
706 706 c, t dbSNP:768064931
742 742 a, g, t dbSNP:370819441
747 747 a, g dbSNP:757804856
757 757 c, g dbSNP:747495835
761 761 c, t dbSNP:778170459
767 767 c, t dbSNP:551175992
775 775 a, g dbSNP:758720903
782 782 c, t dbSNP:376677137
784 784 a, g dbSNP:372399682
797 797 c, t dbSNP:775033600
804 804 -, ctta dbSNP:779446409
819 819 a, g dbSNP:35918099
822 822 c, t dbSNP:199940585
835 835 a, g dbSNP:778192508
844 844 a, g dbSNP:758709109
846 846 a, g dbSNP:748501058
858 858 c, g dbSNP:779115246
865 865 a, g dbSNP:757114207
874 874 a, t dbSNP:769304507
885 885 c, g dbSNP:543324204
918 918 a, g dbSNP:773619472
921 921 a, t dbSNP:74378111
927 927 a, c dbSNP:144713478
930 930 c, g dbSNP:753599408
945 945 a, g dbSNP:367890072
949 949 a, g dbSNP:757165202
955 955 a, g dbSNP:145218540
965 965 c, t dbSNP:778253892
969 969 a, g dbSNP:139598810
970 970 a, g dbSNP:749622712
977 977 a, g dbSNP:780454944
995 995 c, t dbSNP:770181391
1005 1005 a, g dbSNP:746059460
1006 1006 a, c dbSNP:781395541
1008 1008 c, t dbSNP:757282952
1010 1010 c, t dbSNP:746974489
1011 1011 a, g dbSNP:371181176