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STAT5B signal transducer and activator of transcription 5B [Homo sapiens (human)]

Gene Symbol STAT5B
Entrez Gene ID 6777
Full Name signal transducer and activator of transcription 5B
Synonyms STAT5
General protein information
Preferred Names
signal transducer and activator of transcription 5B
Names
signal transducer and activator of transcription 5B
transcription factor STAT5B
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

17

17q11.2

Summary The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. This gene was found to fuse to retinoic acid receptor-alpha (RARA) gene in a small subset of acute promyelocytic leukemias (APLL). The dysregulation of the signaling pathways mediated by this protein may be the cause of the APLL. [provided by RefSeq, Jul 2008]. lac of sum
Disorder MIM:

604260

Disorder Html: Leukemia, acute promyelocytic, STAT5B/RARA type (3); Growth hormone





The following STAT5B gene sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the STAT5B gene which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu50617 XM_005257625 PREDICTED: Homo sapiens signal transducer and activator of transcription 5B (STAT5B), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 12-14 Quote Price
OHu50618 XM_005257626 PREDICTED: Homo sapiens signal transducer and activator of transcription 5B (STAT5B), transcript variant X2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $319
OHu25538 NM_012448 Homo sapiens signal transducer and activator of transcription 5B (STAT5B), mRNA. pcDNA3.1+/C-(K)DYK or customized vector 5-7 Quote Price

*Business Day
**You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.


CloneID OHu50617
Accession Version XM_005257625.2
Sequence Information ORF Nucleotide Sequence (Length: 2082bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product signal transducer and activator of transcription 5B isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_010783.16) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 12, 2015 this sequence version replaced gi:530412764. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
ATGAACACGT ATGACCGCTG CCCCATGGAG CTGGTCCGCT GCATCCGCCA TATATTGTAC 
AATGAACAGA GGTTGGTCCG AGAAGCCAAC AATGGTAGCT CTCCAGCTGG AAGCCTTGCT
GATGCCATGT CCCAGAAACA CCTCCAGATC AACCAGACGT TTGAGGAGCT GCGACTGGTC
ACGCAGGACA CAGAGAATGA GTTAAAAAAG CTGCAGCAGA CTCAGGAGTA CTTCATCATC
CAGTACCAGG AGAGCCTGAG GATCCAAGCT CAGTTTGGCC CGCTGGCCCA GCTGAGCCCC
CAGGAGCGTC TGAGCCGGGA GACGGCCCTC CAGCAGAAGC AGGTGTCTCT GGAGGCCTGG
TTGCAGCGTG AGGCACAGAC ACTGCAGCAG TACCGCGTGG AGCTGGCCGA GAAGCACCAG
AAGACCCTGC AGCTGCTGCG GAAGCAGCAG ACCATCATCC TGGATGACGA GCTGATCCAG
TGGAAGCGGC GGCAGCAGCT GGCCGGGAAC GGCGGGCCCC CCGAGGGCAG CCTGGACGTG
CTACAGTCCT GGTGTGAGAA GTTGGCCGAG ATCATCTGGC AGAACCGGCA GCAGATCCGC
AGGGCTGAGC ACCTCTGCCA GCAGCTGCCC ATCCCCGGCC CAGTGGAGGA GATGCTGGCC
GAGGTCAACG CCACCATCAC GGACATTATC TCAGCCCTGG TGACCAGCAC GTTCATCATT
GAGAAGCAGC CTCCTCAGGT CCTGAAGACC CAGACCAAGT TTGCAGCCAC TGTGCGCCTG
CTGGTGGGCG GGAAGCTGAA CGTGCACATG AACCCCCCCC AGGTGAAGGC CACCATCATC
AGTGAGCAGC AGGCCAAGTC TCTGCTCAAG AACGAGAACA CCCGCAATGA TTACAGTGGC
GAGATCTTGA ACAACTGCTG CGTCATGGAG TACCACCAAG CCACAGGCAC CCTTAGTGCC
CACTTCAGGA ATATGTCCCT GAAACGAATT AAGAGGTCAG ACCGTCGTGG GGCAGAGTCG
GTGACAGAAG AAAAATTTAC AATCCTGTTT GAATCCCAGT TCAGTGTTGG TGGAAATGAG
CTGGTTTTTC AAGTCAAGAC CCTGTCCCTG CCAGTGGTGG TGATCGTTCA TGGCAGCCAG
GACAACAATG CGACGGCCAC TGTTCTCTGG GACAATGCTT TTGCAGAGCC TGGCAGGGTG
CCATTTGCCG TGCCTGACAA AGTGCTGTGG CCACAGCTGT GTGAGGCGCT CAACATGAAA
TTCAAGGCCG AAGTGCAGAG CAACCGGGGC CTGACCAAGG AGAACCTCGT GTTCCTGGCG
CAGAAACTGT TCAACAACAG CAGCAGCCAC CTGGAGGACT ACAGTGGCCT GTCTGTGTCC
TGGTCCCAGT TCAACAGGGA GAATTTACCA GGACGGAATT ACACTTTCTG GCAATGGTTT
GACGGTGTGA TGGAAGTGTT AAAAAAACAT CTCAAGCCTC ATTGGAATGA TGGGGCCATT
TTGGGGTTTG TAAACAAGCA ACAGGCCCAT GACCTACTCA TTAACAAGCC AGATGGGACC
TTCCTCCTGA GATTCAGTGA CTCAGAAATT GGCGGCATCA CCATTGCTTG GAAGTTTGAT
TCTCAGGAAA GAATGTTTTG GAATCTGATG CCTTTTACCA CCAGAGACTT CTCCATTCGG
TCCCTAGCCG ACCGCTTGGG AGACTTGAAT TACCTTATCT ACGTGTTTCC TGATCGGCCA
AAAGATGAAG TATACTCCAA ATACTACACA CCAGTTCCCT GCGAGTCTGC TACTGCTAAA
GCTGTTGATG GATACGTGAA GCCACAGATC AAGCAAGTGG TCCCTGAGTT TGTGAACGCA
TCTGCAGATG CCGGGGGCGG CAGCGCCACG TACATGGACC AGGCCCCCTC CCCAGCTGTG
TGTCCCCAGG CTCACTATAA CATGTACCCA CAGAACCCTG ACTCAGTCCT TGACACCGAT
GGGGACTTCG ATCTGGAGGA CACAATGGAC GTAGCGCGGC GTGTGGAGGA GCTCCTGGGC
CGGCCAATGG ACAGTCAGTG GATCCCGCAC GCACAATCGT GA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqXP_005257682.1
CDS87..2168
Misc Feature(1)90..179(+)
Misc Feature(2)216..794(+)
Misc Feature(3)798..1553(+)
Misc Feature(4)1521..1955(+)
Misc Feature(5)1602..1736(+)
Misc Feature(6)1731..1781(+)
Misc Feature(7)1761..1916(+)
Translation
Position Chain Variation Link
42 42 -, c dbSNP:34224133
60 60 c, t dbSNP:750016838
82 82 c, t dbSNP:767959957
94 94 c, t dbSNP:766427008
95 95 a, g dbSNP:760931428
102 102 c, t dbSNP:199894785
119 119 g, t dbSNP:768466007
120 120 a, g dbSNP:748978416
132 132 c, t dbSNP:775502922
133 133 a, g dbSNP:769688321
134 134 a, c dbSNP:745807026
141 141 c, t dbSNP:780896511
148 148 a, g dbSNP:756794353
149 149 c, t dbSNP:576854811
159 159 c, t dbSNP:777518670
166 166 a, g dbSNP:758843144
174 174 a, g dbSNP:374711620
179 179 c, t dbSNP:555285694
193 193 c, t dbSNP:2277619
200 200 c, t dbSNP:770921312
207 207 a, g dbSNP:760681474
215 215 -, gtc dbSNP:764574191
227 227 c, t dbSNP:772912945
232 232 a, c dbSNP:771586939
233 233 c, g dbSNP:148793995
239 239 c, g dbSNP:778582220
244 244 a, c dbSNP:768919211
245 245 a, g dbSNP:144367484
252 252 a, g dbSNP:780393081
258 258 c, t dbSNP:121908502
259 259 a, c, g dbSNP:149614939
268 268 c, t dbSNP:138255473
269 269 a, g dbSNP:556691083
273 273 -, t dbSNP:35910895
278 278 a, g dbSNP:147066043
283 283 a, g dbSNP:764319884
286 286 a, g dbSNP:200923475
290 290 a, g dbSNP:759250756
304 304 a, c dbSNP:753748722
309 309 c, g dbSNP:759946844
329 329 a, g dbSNP:61755324
340 340 a, g dbSNP:376439732
364 364 c, g dbSNP:746169589
367 367 a, c, t dbSNP:143092033
368 368 a, g dbSNP:747457595
373 373 a, c dbSNP:777956676
379 379 c, t dbSNP:758519390
386 386 c, t dbSNP:748406387
403 403 a, g dbSNP:779220548
408 408 a, g dbSNP:755979362
412 412 c, t dbSNP:139065819
425 425 a, g dbSNP:563111908
429 429 c, g dbSNP:757272257
431 431 c, g dbSNP:751423677
441 441 g, t dbSNP:377601290
442 442 c, g dbSNP:762397922
454 454 a, g dbSNP:200900246
466 466 c, t dbSNP:764799602
468 468 c, t dbSNP:759101528
480 480 c, t dbSNP:777110652
482 482 c, t dbSNP:377043175
483 483 a, g dbSNP:761283639
494 494 c, t dbSNP:555155085
554 554 c, t dbSNP:764709139
591 591 a, g dbSNP:759281260
593 593 a, g dbSNP:753400820
599 599 c, t dbSNP:766796346
603 603 c, g dbSNP:760893128
624 624 a, g dbSNP:773861955
653 653 c, t dbSNP:771823136
667 667 a, t dbSNP:375808218
673 673 a, g dbSNP:376599040
684 684 c, t dbSNP:199982340
685 685 a, g dbSNP:754523154
688 688 a, g dbSNP:748817046
699 699 a, c dbSNP:779603963
722 722 a, c, t dbSNP:142321005
732 732 a, g dbSNP:750074223
735 735 a, g dbSNP:768028861
741 741 c, t dbSNP:757650048
746 746 c, t dbSNP:752128975
748 748 a, c dbSNP:572536541
749 749 a, g dbSNP:763508760
755 755 c, t dbSNP:372624709
756 756 a, g dbSNP:553989095
767 767 a, g dbSNP:759793357
771 771 a, g, t dbSNP:539091753
796 796 c, t dbSNP:753213429
797 797 a, g dbSNP:59491077
801 801 a, g dbSNP:759562375
803 803 c, t dbSNP:754071605
805 805 c, t dbSNP:754879860
809 809 a, g dbSNP:766656341
822 822 c, g dbSNP:760876362
857 857 c, t dbSNP:774063058
860 860 a, g dbSNP:768467135
861 861 c, t dbSNP:762833594
862 862 a, g dbSNP:143171571
875 875 c, t dbSNP:769445041
876 876 a, g dbSNP:745315653
878 878 a, g dbSNP:780841478
887 887 c, t dbSNP:770762035
888 888 a, g dbSNP:750053820
891 891 c, t dbSNP:778035877
899 899 c, t dbSNP:188781721
901 901 c, g dbSNP:753166147
903 903 a, c dbSNP:779416144
905 905 a, c dbSNP:61749920
906 906 -, c dbSNP:761761205
906 906 a, c, t dbSNP:144993426
906 906 -, c dbSNP:764965457
916 916 a, c dbSNP:28706683
917 917 c, t dbSNP:766426761
944 944 a, g dbSNP:760927580
959 959 c, t dbSNP:750619589
961 961 a, g dbSNP:202077096
965 965 c, t dbSNP:763821368
966 966 a, g dbSNP:199998167
968 968 c, t dbSNP:144060305
980 980 c, t dbSNP:780140449
986 986 c, t dbSNP:756173306
1007 1007 c, t dbSNP:200710135
1010 1010 c, t dbSNP:765486148
1023 1023 a, c dbSNP:767714314
1030 1030 c, t dbSNP:757419103
1036 1036 c, t dbSNP:752592229
1072 1072 a, g dbSNP:373996796
1092 1092 c, t dbSNP:781121963
1093 1093 a, g dbSNP:757544937
1101 1101 a, g dbSNP:751798472
1106 1106 a, g dbSNP:765151427
1139 1139 a, g dbSNP:111880437
1153 1153 g, t dbSNP:753839151
1188 1188 c, t dbSNP:770018533
1190 1190 a, g dbSNP:760116387
1196 1196 a, g dbSNP:776951968
1207 1207 c, t dbSNP:201911697
1241 1241 a, g dbSNP:775941580
1248 1248 a, g dbSNP:747016816
1259 1259 c, t dbSNP:777993133
1285 1285 a, t dbSNP:778265187
1295 1295 c, g dbSNP:772239606
1296 1296 a, g dbSNP:748404440
1306 1306 a, g dbSNP:146678334
1319 1319 a, g dbSNP:769636293
1333 1333 c, t dbSNP:200200711
1334 1334 a, g dbSNP:781030237
1355 1355 a, c, t dbSNP:373036522
1358 1358 a, g dbSNP:777292743
1359 1359 c, g dbSNP:757850017
1367 1367 c, t dbSNP:752406003
1369 1369 a, g dbSNP:764726823
1373 1373 a, c, g dbSNP:143172354
1385 1385 a, g dbSNP:140632704
1387 1387 a, g dbSNP:766828492
1394 1394 c, t dbSNP:761303284
1395 1395 a, g dbSNP:142918872
1408 1408 a, g dbSNP:375789837
1428 1428 a, g dbSNP:761733940
1437 1437 c, g dbSNP:569804189
1440 1440 a, g dbSNP:768821055
1441 1441 a, t dbSNP:749508222
1442 1442 a, g dbSNP:776333900
1448 1448 c, t dbSNP:139437059
1460 1460 c, t dbSNP:758513855
1470 1470 a, t dbSNP:777627496
1483 1483 a, g dbSNP:547984168
1494 1494 c, t dbSNP:561888537
1520 1520 a, g dbSNP:775637267
1529 1529 c, t dbSNP:75130700
1532 1532 c, t dbSNP:763332867
1549 1549 a, g dbSNP:374070270
1556 1556 c, t dbSNP:746737564
1559 1559 c, t dbSNP:572365056
1568 1568 c, t dbSNP:771960501
1625 1625 c, g dbSNP:1065376
1634 1634 a, g dbSNP:376254568
1643 1643 g, t dbSNP:765507952
1653 1653 c, t dbSNP:759739934
1658 1658 a, g dbSNP:773037490
1667 1667 c, t dbSNP:771869116
1676 1676 g, t dbSNP:144158108
1679 1679 c, t dbSNP:761686912
1687 1687 c, g dbSNP:774286856
1692 1692 c, g dbSNP:121908501
1710 1710 a, c dbSNP:367846125
1712 1712 a, g dbSNP:144106094
1731 1731 c, t dbSNP:150697956
1739 1739 g, t dbSNP:767238307
1746 1746 a, g dbSNP:761602572
1763 1763 c, t dbSNP:1057936
1765 1765 a, g dbSNP:201246187
1769 1769 c, t dbSNP:768697949
1775 1775 c, t dbSNP:141979661
1776 1776 a, g dbSNP:148568485
1795 1795 a, c dbSNP:370769279
1799 1799 c, t dbSNP:370257486
1808 1808 c, t dbSNP:147503881
1821 1821 c, t dbSNP:773533491
1822 1822 a, g dbSNP:776285574
1826 1826 a, g dbSNP:771200360
1840 1840 a, g dbSNP:747470866
1850 1850 c, t dbSNP:777984202
1863 1863 c, t dbSNP:758951069
1865 1865 c, t dbSNP:186347987
1869 1869 a, g dbSNP:778995803
1877 1877 c, t dbSNP:755002810
1888 1888 c, t dbSNP:200333924
1890 1890 a, g dbSNP:779977175
1892 1892 c, t dbSNP:756400339
1894 1894 a, g dbSNP:200738371
1901 1901 c, t dbSNP:369507540
1907 1907 a, g dbSNP:764006844
1919 1919 a, g dbSNP:753163911
1921 1921 a, t dbSNP:752681313
1922 1922 a, g dbSNP:777259731
1925 1925 a, g dbSNP:765329195
1934 1934 a, g dbSNP:781501709
1943 1943 c, t dbSNP:201825895
1944 1944 a, g dbSNP:752593400
1946 1946 a, g dbSNP:778825869
1952 1952 a, t dbSNP:754980286
1956 1956 a, g dbSNP:551009906
1958 1958 c, t dbSNP:143157773
1964 1964 c, t dbSNP:529306345
1965 1965 a, g dbSNP:750095303
1970 1970 c, t dbSNP:767216293
1975 1975 c, t dbSNP:139131471
1976 1976 a, g dbSNP:774739413
1982 1982 a, g dbSNP:768971207
1989 1989 g, t dbSNP:200042237
2019 2019 c, t dbSNP:372734271
2028 2028 a, g dbSNP:769925436
2034 2034 a, c dbSNP:745998088
2054 2054 c, t dbSNP:765726344
2061 2061 a, g dbSNP:760069627
2063 2063 c, t dbSNP:776893445
2065 2065 a, g dbSNP:372909572
2066 2066 c, g, t dbSNP:773512310
2069 2069 a, g dbSNP:368735480
2075 2075 c, t dbSNP:749104172
2086 2086 a, g dbSNP:779876449
2090 2090 a, g dbSNP:756044618
2096 2096 c, t dbSNP:146467656
2097 2097 a, g dbSNP:780699949
2102 2102 a, g dbSNP:756695652
2104 2104 a, g dbSNP:751214121
2107 2107 a, g dbSNP:763716770
2120 2120 c, t dbSNP:758060015
2128 2128 a, g dbSNP:138115420
2133 2133 a, g dbSNP:765607800
2138 2138 c, t dbSNP:760154055
2141 2141 c, t dbSNP:546587896
2148 2148 a, c dbSNP:777230664
2152 2152 c, t dbSNP:752309096
2156 2156 c, t dbSNP:375173590
2157 2157 a, g dbSNP:760771231
2162 2162 a, g dbSNP:568497349
2163 2163 c, t dbSNP:547016204
2164 2164 c, t dbSNP:748370281
2165 2165 a, g dbSNP:775177987
2170 2170 c, t dbSNP:375927948
2172 2172 c, t dbSNP:769580915
2173 2173 a, g dbSNP:371610966
2174 2174 c, t dbSNP:781038869
2175 2175 a, g dbSNP:527627852
2177 2177 c, t dbSNP:746576126
2179 2179 g, t dbSNP:560198087
2180 2180 c, t dbSNP:114275908
2193 2193 c, t dbSNP:752357162
2200 2200 g, t dbSNP:779170624
2202 2202 c, t dbSNP:2230097
2204 2204 a, c, t dbSNP:367656244
2217 2217 a, c dbSNP:767061487
2237 2237 c, t dbSNP:34320895
2240 2240 a, g dbSNP:755801250
2246 2246 c, t dbSNP:562669599
2266 2266 a, g dbSNP:543937773
2285 2285 a, g dbSNP:773901213
2338 2338 (tg)20, 22, 23 dbSNP:3222523
2351 2351 -, ttgt dbSNP:201167281
2352 2352 -, tgtg dbSNP:57573850
2352 2352 -, tg dbSNP:111734751
2353 2353 -, tt dbSNP:768754690
2354 2354 c, t dbSNP:573378468
2354 2354 -, t dbSNP:34396327
2355 2355 g, t dbSNP:1869364
2378 2378 -, tgtg dbSNP:770796002
2378 2378 -, tg dbSNP:770079556
2379 2379 -, gt dbSNP:397840818
2380 2380 -, tg dbSNP:146723548
2380 2380 c, t dbSNP:539831609
2381 2381 -, tg dbSNP:369424383
2392 2392 c, t dbSNP:180927761
2393 2393 a, g dbSNP:572099089
2409 2409 c, t dbSNP:190849391
2443 2443 a, g dbSNP:575762109
2499 2499 a, g dbSNP:75341760
2517 2517 c, t dbSNP:143357938
2640 2640 c, t dbSNP:568560438
2676 2676 c, t dbSNP:187214937
2711 2711 c, t dbSNP:756745694
2717 2717 c, t dbSNP:535021090
2719 2719 c, t dbSNP:114475755
2756 2756 c, t dbSNP:181812855
2774 2774 g, t dbSNP:533239913
2789 2789 a, g dbSNP:568985190
2803 2803 c, t dbSNP:549000823
2815 2815 a, t dbSNP:765673447
2852 2852 c, t dbSNP:755565616
2856 2856 c, t dbSNP:754196319
2868 2868 a, g dbSNP:528994237
2872 2872 a, g dbSNP:766769074
2901 2901 g, t dbSNP:561454695
2913 2913 -, at dbSNP:773623045
2949 2949 a, g dbSNP:117074548
2954 2954 c, t dbSNP:750676055
2957 2957 c, g dbSNP:528094698
2972 2972 a, g dbSNP:569658173
2991 2991 c, g dbSNP:139332839
3037 3037 c, t dbSNP:761815470
3062 3062 c, t dbSNP:113824843
3063 3063 a, g dbSNP:146827392
3090 3090 a, g dbSNP:774551681
3103 3103 a, g dbSNP:557630320
3109 3109 g, t dbSNP:542452702
3110 3110 c, t dbSNP:575040646
3137 3137 g, t dbSNP:553526475
3189 3189 c, t dbSNP:781180792
3195 3195 a, g dbSNP:535083491
3198 3198 c, g dbSNP:141028136
3263 3263 a, t dbSNP:148224780
3272 3272 c, t dbSNP:539396877
3277 3277 c, t dbSNP:768477548
3313 3313 c, t dbSNP:569123522
3343 3343 c, t dbSNP:78682061
3365 3365 a, c dbSNP:190178825
3380 3380 a, g dbSNP:775399441
3404 3404 a, g dbSNP:567884387
3410 3410 -, g dbSNP:35987392
3423 3423 a, g dbSNP:546302398
3452 3452 c, t dbSNP:143058452
3454 3454 a, g dbSNP:769730435
3470 3470 c, t dbSNP:376858672
3471 3471 a, g dbSNP:563975009
3514 3514 a, g dbSNP:747203679
3524 3524 a, g dbSNP:545777471
3534 3534 c, g dbSNP:549947506
3543 3543 c, t dbSNP:563976387
3564 3564 c, t dbSNP:780994364
3565 3565 a, g dbSNP:770415612
3566 3566 g, t dbSNP:116244359
3572 3572 a, g dbSNP:575102422
3583 3583 c, t dbSNP:553589699
3590 3590 c, t dbSNP:746486622
3591 3591 a, g dbSNP:541195855
3623 3623 c, t dbSNP:577264997
3679 3679 a, t dbSNP:558721369
3705 3705 a, g dbSNP:184810925
3715 3715 -, t dbSNP:34694406
3728 3728 a, g dbSNP:373852784
3730 3730 -, a dbSNP:528234693
3782 3782 a, g dbSNP:116906338
3810 3810 a, g dbSNP:149034065
3813 3813 a, t dbSNP:556577422
3814 3814 -, attt dbSNP:770152434
3814 3814 a, g dbSNP:181312613
3830 3830 c, t dbSNP:111883304
3857 3857 c, g, t dbSNP:112972196
3931 3931 a, g dbSNP:780358197
3933 3933 a, g dbSNP:188617884
3935 3935 c, t dbSNP:564340503
3936 3936 a, g dbSNP:756476830
3944 3944 g, t dbSNP:538575383
4000 4000 c, t dbSNP:750588480
4001 4001 a, g dbSNP:767622858
4042 4042 c, t dbSNP:762164467
4065 4065 a, g dbSNP:551942072
4069 4069 c, g dbSNP:530550813
4071 4071 g, t dbSNP:146438448
4094 4094 c, g dbSNP:548933669
4100 4100 g, t dbSNP:145236827
4108 4108 c, t dbSNP:751566413
4127 4127 a, g dbSNP:547241866
4145 4145 a, g dbSNP:183533045
4178 4178 a, g dbSNP:779546182
4269 4269 a, g dbSNP:757776699
4303 4303 c, t dbSNP:191284679
4305 4305 c, t dbSNP:754414220
4312 4312 c, t dbSNP:767007096
4314 4314 c, t dbSNP:188882610
4336 4336 c, t dbSNP:113234237
4356 4356 a, c dbSNP:140444425
4381 4381 a, c dbSNP:543521202
4413 4413 c, t dbSNP:576042434
4420 4420 c, t dbSNP:764287553
4436 4436 c, t dbSNP:185708008
4480 4480 c, t dbSNP:762930453
4486 4486 c, g, t dbSNP:59138731
4487 4487 a, g dbSNP:146750609
4527 4527 c, t dbSNP:15456
4533 4533 a, c dbSNP:535386024
4555 4555 c, g dbSNP:149725455
4595 4595 a, c dbSNP:1046104
4602 4602 a, g dbSNP:527587051
4626 4626 c, t dbSNP:769643619
4646 4646 -, a dbSNP:373091385

Target ORF information:

RefSeq Version XM_005257625
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens signal transducer and activator of transcription 5B (STAT5B), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_005257625

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
ATGAACACGT ATGACCGCTG CCCCATGGAG CTGGTCCGCT GCATCCGCCA TATATTGTAC 
AATGAACAGA GGTTGGTCCG AGAAGCCAAC AATGGTAGCT CTCCAGCTGG AAGCCTTGCT
GATGCCATGT CCCAGAAACA CCTCCAGATC AACCAGACGT TTGAGGAGCT GCGACTGGTC
ACGCAGGACA CAGAGAATGA GTTAAAAAAG CTGCAGCAGA CTCAGGAGTA CTTCATCATC
CAGTACCAGG AGAGCCTGAG GATCCAAGCT CAGTTTGGCC CGCTGGCCCA GCTGAGCCCC
CAGGAGCGTC TGAGCCGGGA GACGGCCCTC CAGCAGAAGC AGGTGTCTCT GGAGGCCTGG
TTGCAGCGTG AGGCACAGAC ACTGCAGCAG TACCGCGTGG AGCTGGCCGA GAAGCACCAG
AAGACCCTGC AGCTGCTGCG GAAGCAGCAG ACCATCATCC TGGATGACGA GCTGATCCAG
TGGAAGCGGC GGCAGCAGCT GGCCGGGAAC GGCGGGCCCC CCGAGGGCAG CCTGGACGTG
CTACAGTCCT GGTGTGAGAA GTTGGCCGAG ATCATCTGGC AGAACCGGCA GCAGATCCGC
AGGGCTGAGC ACCTCTGCCA GCAGCTGCCC ATCCCCGGCC CAGTGGAGGA GATGCTGGCC
GAGGTCAACG CCACCATCAC GGACATTATC TCAGCCCTGG TGACCAGCAC GTTCATCATT
GAGAAGCAGC CTCCTCAGGT CCTGAAGACC CAGACCAAGT TTGCAGCCAC TGTGCGCCTG
CTGGTGGGCG GGAAGCTGAA CGTGCACATG AACCCCCCCC AGGTGAAGGC CACCATCATC
AGTGAGCAGC AGGCCAAGTC TCTGCTCAAG AACGAGAACA CCCGCAATGA TTACAGTGGC
GAGATCTTGA ACAACTGCTG CGTCATGGAG TACCACCAAG CCACAGGCAC CCTTAGTGCC
CACTTCAGGA ATATGTCCCT GAAACGAATT AAGAGGTCAG ACCGTCGTGG GGCAGAGTCG
GTGACAGAAG AAAAATTTAC AATCCTGTTT GAATCCCAGT TCAGTGTTGG TGGAAATGAG
CTGGTTTTTC AAGTCAAGAC CCTGTCCCTG CCAGTGGTGG TGATCGTTCA TGGCAGCCAG
GACAACAATG CGACGGCCAC TGTTCTCTGG GACAATGCTT TTGCAGAGCC TGGCAGGGTG
CCATTTGCCG TGCCTGACAA AGTGCTGTGG CCACAGCTGT GTGAGGCGCT CAACATGAAA
TTCAAGGCCG AAGTGCAGAG CAACCGGGGC CTGACCAAGG AGAACCTCGT GTTCCTGGCG
CAGAAACTGT TCAACAACAG CAGCAGCCAC CTGGAGGACT ACAGTGGCCT GTCTGTGTCC
TGGTCCCAGT TCAACAGGGA GAATTTACCA GGACGGAATT ACACTTTCTG GCAATGGTTT
GACGGTGTGA TGGAAGTGTT AAAAAAACAT CTCAAGCCTC ATTGGAATGA TGGGGCCATT
TTGGGGTTTG TAAACAAGCA ACAGGCCCAT GACCTACTCA TTAACAAGCC AGATGGGACC
TTCCTCCTGA GATTCAGTGA CTCAGAAATT GGCGGCATCA CCATTGCTTG GAAGTTTGAT
TCTCAGGAAA GAATGTTTTG GAATCTGATG CCTTTTACCA CCAGAGACTT CTCCATTCGG
TCCCTAGCCG ACCGCTTGGG AGACTTGAAT TACCTTATCT ACGTGTTTCC TGATCGGCCA
AAAGATGAAG TATACTCCAA ATACTACACA CCAGTTCCCT GCGAGTCTGC TACTGCTAAA
GCTGTTGATG GATACGTGAA GCCACAGATC AAGCAAGTGG TCCCTGAGTT TGTGAACGCA
TCTGCAGATG CCGGGGGCGG CAGCGCCACG TACATGGACC AGGCCCCCTC CCCAGCTGTG
TGTCCCCAGG CTCACTATAA CATGTACCCA CAGAACCCTG ACTCAGTCCT TGACACCGAT
GGGGACTTCG ATCTGGAGGA CACAATGGAC GTAGCGCGGC GTGTGGAGGA GCTCCTGGGC
CGGCCAATGG ACAGTCAGTG GATCCCGCAC GCACAATCGT GA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu50618
Accession Version XM_005257626.3
Sequence Information ORF Nucleotide Sequence (Length: 1494bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product signal transducer and activator of transcription 5B isoform X2
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_010783.16) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 12, 2015 this sequence version replaced gi:578831312. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
ATGGCTGTGT GGATACAAGC TCAGCAGCTC CAAGGAGAAG CCCTTCATCA GATGCAAGCG 
TTATATGGCC AGCATTTTCC CATTGAGGTG CGGCATTATT TATCCCAGTG GATTGAAAGC
CAAGCATGGG ACTCAGTAGA TCTTGATAAT CCACAGGAGA ACATTAAGGC CACCCAGCTC
CTGGAGGGCC TGGTGCAGGA GCTGCAGAAG AAGGCAGAGC ACCAGGTGGG GGAAGATGGG
TTTTTACTGA AGATCAAGCT GGGGCACTAT GCCACACAGC TCCAGAACAC GTATGACCGC
TGCCCCATGG AGCTGGTCCG CTGCATCCGC CATATATTGT ACAATGAACA GAGGTTGGTC
CGAGAAGCCA ACAATGGTAG CTCTCCAGCT GGAAGCCTTG CTGATGCCAT GTCCCAGAAA
CACCTCCAGA TCAACCAGAC GTTTGAGGAG CTGCGACTGG TCACGCAGGA CACAGAGAAT
GAGTTAAAAA AGCTGCAGCA GACTCAGGAG TACTTCATCA TCCAGTACCA GGAGAGCCTG
AGGATCCAAG CTCAGTTTGG CCCGCTGGCC CAGCTGAGCC CCCAGGAGCG TCTGAGCCGG
GAGACGGCCC TCCAGCAGAA GCAGGTGTCT CTGGAGGCCT GGTTGCAGCG TGAGGCACAG
ACACTGCAGC AGTACCGCGT GGAGCTGGCC GAGAAGCACC AGAAGACCCT GCAGCTGCTG
CGGAAGCAGC AGACCATCAT CCTGGATGAC GAGCTGATCC AGTGGAAGCG GCGGCAGCAG
CTGGCCGGGA ACGGCGGGCC CCCCGAGGGC AGCCTGGACG TGCTACAGTC CTGGTGTGAG
AAGTTGGCCG AGATCATCTG GCAGAACCGG CAGCAGATCC GCAGGGCTGA GCACCTCTGC
CAGCAGCTGC CCATCCCCGG CCCAGTGGAG GAGATGCTGG CCGAGGTCAA CGCCACCATC
ACGGACATTA TCTCAGCCCT GGTGACCAGC ACGTTCATCA TTGAGAAGCA GCCTCCTCAG
GTCCTGAAGA CCCAGACCAA GTTTGCAGCC ACTGTGCGCC TGCTGGTGGG CGGGAAGCTG
AACGTGCACA TGAACCCCCC CCAGGTGAAG GCCACCATCA TCAGTGAGCA GCAGGCCAAG
TCTCTGCTCA AGAACGAGAA CACCCGCAAT GATTACAGTG GCGAGATCTT GAACAACTGC
TGCGTCATGG AGTACCACCA AGCCACAGGC ACCCTTAGTG CCCACTTCAG GAATATGTCC
CTGAAACGAA TTAAGAGGTC AGACCGTCGT GGGGCAGAGT CGGTGACAGA AGAAAAATTT
ACAATCCTGT TTGAATCCCA GTTCAGTGTT GGTGGAAATG AGCTGGTTTT TCAAGTCAAG
ACCCTGTCCC TGCCAGTGGT GGTGATCGTT CATGGCAGCC AGGACAACAA TGCGACGGCC
ACTGTTCTCT GGGACAATGC TTTTGCAGAG CCTAATATAG GATTTGACTG TTAG
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqXP_005257683.1
CDS224..1717
Misc Feature(1)227..601(+)
Misc Feature(2)635..1213(+)
Misc Feature(3)1217..>1696(+)
Translation
Position Chain Variation Link
88 88 c, t dbSNP:550574417
91 91 a, g dbSNP:535413649
154 154 -, gggcgggc dbSNP:539889607
214 214 a, g dbSNP:765106938
222 222 a, c dbSNP:754494821
225 225 c, t dbSNP:112572423
227 227 a, g dbSNP:113461014
230 230 a, g dbSNP:144024535
236 236 a, t dbSNP:376041480
256 256 a, g dbSNP:760427357
304 304 -, c dbSNP:34224133
322 322 c, t dbSNP:750016838
344 344 c, t dbSNP:767959957
362 362 a, g dbSNP:755543502
363 363 a, t dbSNP:750113759
378 378 a, t dbSNP:139130762
380 380 c, g dbSNP:762274331
385 385 c, t dbSNP:201916641
394 394 c, t dbSNP:200136266
396 396 c, t dbSNP:763601763
403 403 c, g dbSNP:200624718
404 404 c, t dbSNP:769947666
410 410 a, g dbSNP:759481948
420 420 a, g dbSNP:750520285
427 427 a, g dbSNP:776922169
451 451 g, t dbSNP:553370889
461 461 a, g dbSNP:747225467
470 470 c, t dbSNP:146176992
487 487 -, g dbSNP:746112176
493 493 c, t dbSNP:768410888
501 501 a, g dbSNP:749258998
503 503 c, t dbSNP:199645527
513 513 c, t dbSNP:766427008
514 514 a, g dbSNP:760931428
521 521 c, t dbSNP:199894785
538 538 g, t dbSNP:768466007
539 539 a, g dbSNP:748978416
551 551 c, t dbSNP:775502922
552 552 a, g dbSNP:769688321
553 553 a, c dbSNP:745807026
560 560 c, t dbSNP:780896511
567 567 a, g dbSNP:756794353
568 568 c, t dbSNP:576854811
578 578 c, t dbSNP:777518670
585 585 a, g dbSNP:758843144
593 593 a, g dbSNP:374711620
598 598 c, t dbSNP:555285694
612 612 c, t dbSNP:2277619
619 619 c, t dbSNP:770921312
626 626 a, g dbSNP:760681474
634 634 -, gtc dbSNP:764574191
646 646 c, t dbSNP:772912945
651 651 a, c dbSNP:771586939
652 652 c, g dbSNP:148793995
658 658 c, g dbSNP:778582220
663 663 a, c dbSNP:768919211
664 664 a, g dbSNP:144367484
671 671 a, g dbSNP:780393081
677 677 c, t dbSNP:121908502
678 678 a, c, g dbSNP:149614939
687 687 c, t dbSNP:138255473
688 688 a, g dbSNP:556691083
692 692 -, t dbSNP:35910895
697 697 a, g dbSNP:147066043
702 702 a, g dbSNP:764319884
705 705 a, g dbSNP:200923475
709 709 a, g dbSNP:759250756
723 723 a, c dbSNP:753748722
728 728 c, g dbSNP:759946844
748 748 a, g dbSNP:61755324
759 759 a, g dbSNP:376439732
783 783 c, g dbSNP:746169589
786 786 a, c, t dbSNP:143092033
787 787 a, g dbSNP:747457595
792 792 a, c dbSNP:777956676
798 798 c, t dbSNP:758519390
805 805 c, t dbSNP:748406387
822 822 a, g dbSNP:779220548
827 827 a, g dbSNP:755979362
831 831 c, t dbSNP:139065819
844 844 a, g dbSNP:563111908
848 848 c, g dbSNP:757272257
850 850 c, g dbSNP:751423677
860 860 g, t dbSNP:377601290
861 861 c, g dbSNP:762397922
873 873 a, g dbSNP:200900246
885 885 c, t dbSNP:764799602
887 887 c, t dbSNP:759101528
899 899 c, t dbSNP:777110652
901 901 c, t dbSNP:377043175
902 902 a, g dbSNP:761283639
913 913 c, t dbSNP:555155085
973 973 c, t dbSNP:764709139
1010 1010 a, g dbSNP:759281260
1012 1012 a, g dbSNP:753400820
1018 1018 c, t dbSNP:766796346
1022 1022 c, g dbSNP:760893128
1043 1043 a, g dbSNP:773861955
1072 1072 c, t dbSNP:771823136
1086 1086 a, t dbSNP:375808218
1092 1092 a, g dbSNP:376599040
1103 1103 c, t dbSNP:199982340
1104 1104 a, g dbSNP:754523154
1107 1107 a, g dbSNP:748817046
1118 1118 a, c dbSNP:779603963
1141 1141 a, c, t dbSNP:142321005
1151 1151 a, g dbSNP:750074223
1154 1154 a, g dbSNP:768028861
1160 1160 c, t dbSNP:757650048
1165 1165 c, t dbSNP:752128975
1167 1167 a, c dbSNP:572536541
1168 1168 a, g dbSNP:763508760
1174 1174 c, t dbSNP:372624709
1175 1175 a, g dbSNP:553989095
1186 1186 a, g dbSNP:759793357
1190 1190 a, g, t dbSNP:539091753
1215 1215 c, t dbSNP:753213429
1216 1216 a, g dbSNP:59491077
1220 1220 a, g dbSNP:759562375
1222 1222 c, t dbSNP:754071605
1224 1224 c, t dbSNP:754879860
1228 1228 a, g dbSNP:766656341
1241 1241 c, g dbSNP:760876362
1276 1276 c, t dbSNP:774063058
1279 1279 a, g dbSNP:768467135
1280 1280 c, t dbSNP:762833594
1281 1281 a, g dbSNP:143171571
1294 1294 c, t dbSNP:769445041
1295 1295 a, g dbSNP:745315653
1297 1297 a, g dbSNP:780841478
1306 1306 c, t dbSNP:770762035
1307 1307 a, g dbSNP:750053820
1310 1310 c, t dbSNP:778035877
1318 1318 c, t dbSNP:188781721
1320 1320 c, g dbSNP:753166147
1322 1322 a, c dbSNP:779416144
1324 1324 a, c dbSNP:61749920
1325 1325 -, c dbSNP:761761205
1325 1325 a, c, t dbSNP:144993426
1325 1325 -, c dbSNP:764965457
1335 1335 a, c dbSNP:28706683
1336 1336 c, t dbSNP:766426761
1363 1363 a, g dbSNP:760927580
1378 1378 c, t dbSNP:750619589
1380 1380 a, g dbSNP:202077096
1384 1384 c, t dbSNP:763821368
1385 1385 a, g dbSNP:199998167
1387 1387 c, t dbSNP:144060305
1399 1399 c, t dbSNP:780140449
1405 1405 c, t dbSNP:756173306
1426 1426 c, t dbSNP:200710135
1429 1429 c, t dbSNP:765486148
1442 1442 a, c dbSNP:767714314
1449 1449 c, t dbSNP:757419103
1455 1455 c, t dbSNP:752592229
1491 1491 a, g dbSNP:373996796
1511 1511 c, t dbSNP:781121963
1512 1512 a, g dbSNP:757544937
1520 1520 a, g dbSNP:751798472
1525 1525 a, g dbSNP:765151427
1558 1558 a, g dbSNP:111880437
1572 1572 g, t dbSNP:753839151
1607 1607 c, t dbSNP:770018533
1609 1609 a, g dbSNP:760116387
1615 1615 a, g dbSNP:776951968
1626 1626 c, t dbSNP:201911697
1660 1660 a, g dbSNP:775941580
1667 1667 a, g dbSNP:747016816
1678 1678 c, t dbSNP:777993133

Target ORF information:

RefSeq Version XM_005257626
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens signal transducer and activator of transcription 5B (STAT5B), transcript variant X2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_005257626

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
ATGGCTGTGT GGATACAAGC TCAGCAGCTC CAAGGAGAAG CCCTTCATCA GATGCAAGCG 
TTATATGGCC AGCATTTTCC CATTGAGGTG CGGCATTATT TATCCCAGTG GATTGAAAGC
CAAGCATGGG ACTCAGTAGA TCTTGATAAT CCACAGGAGA ACATTAAGGC CACCCAGCTC
CTGGAGGGCC TGGTGCAGGA GCTGCAGAAG AAGGCAGAGC ACCAGGTGGG GGAAGATGGG
TTTTTACTGA AGATCAAGCT GGGGCACTAT GCCACACAGC TCCAGAACAC GTATGACCGC
TGCCCCATGG AGCTGGTCCG CTGCATCCGC CATATATTGT ACAATGAACA GAGGTTGGTC
CGAGAAGCCA ACAATGGTAG CTCTCCAGCT GGAAGCCTTG CTGATGCCAT GTCCCAGAAA
CACCTCCAGA TCAACCAGAC GTTTGAGGAG CTGCGACTGG TCACGCAGGA CACAGAGAAT
GAGTTAAAAA AGCTGCAGCA GACTCAGGAG TACTTCATCA TCCAGTACCA GGAGAGCCTG
AGGATCCAAG CTCAGTTTGG CCCGCTGGCC CAGCTGAGCC CCCAGGAGCG TCTGAGCCGG
GAGACGGCCC TCCAGCAGAA GCAGGTGTCT CTGGAGGCCT GGTTGCAGCG TGAGGCACAG
ACACTGCAGC AGTACCGCGT GGAGCTGGCC GAGAAGCACC AGAAGACCCT GCAGCTGCTG
CGGAAGCAGC AGACCATCAT CCTGGATGAC GAGCTGATCC AGTGGAAGCG GCGGCAGCAG
CTGGCCGGGA ACGGCGGGCC CCCCGAGGGC AGCCTGGACG TGCTACAGTC CTGGTGTGAG
AAGTTGGCCG AGATCATCTG GCAGAACCGG CAGCAGATCC GCAGGGCTGA GCACCTCTGC
CAGCAGCTGC CCATCCCCGG CCCAGTGGAG GAGATGCTGG CCGAGGTCAA CGCCACCATC
ACGGACATTA TCTCAGCCCT GGTGACCAGC ACGTTCATCA TTGAGAAGCA GCCTCCTCAG
GTCCTGAAGA CCCAGACCAA GTTTGCAGCC ACTGTGCGCC TGCTGGTGGG CGGGAAGCTG
AACGTGCACA TGAACCCCCC CCAGGTGAAG GCCACCATCA TCAGTGAGCA GCAGGCCAAG
TCTCTGCTCA AGAACGAGAA CACCCGCAAT GATTACAGTG GCGAGATCTT GAACAACTGC
TGCGTCATGG AGTACCACCA AGCCACAGGC ACCCTTAGTG CCCACTTCAG GAATATGTCC
CTGAAACGAA TTAAGAGGTC AGACCGTCGT GGGGCAGAGT CGGTGACAGA AGAAAAATTT
ACAATCCTGT TTGAATCCCA GTTCAGTGTT GGTGGAAATG AGCTGGTTTT TCAAGTCAAG
ACCCTGTCCC TGCCAGTGGT GGTGATCGTT CATGGCAGCC AGGACAACAA TGCGACGGCC
ACTGTTCTCT GGGACAATGC TTTTGCAGAG CCTAATATAG GATTTGACTG TTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu25538
Accession Version NM_012448.3
Sequence Information ORF Nucleotide Sequence (Length: 2364bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product signal transducer and activator of transcription 5B
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC065227.1 and U47686.1. This sequence is a reference standard in the RefSeqGene project. On Feb 11, 2004 this sequence version replaced gi:21618343. Summary: The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. This gene was found to fuse to retinoic acid receptor-alpha (RARA) gene in a small subset of acute promyelocytic leukemias (APLL). The dysregulation of the signaling pathways mediated by this protein may be the cause of the APLL. [provided by RefSeq, Jul 2008]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC065227.1, AB208920.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
ATGGCTGTGT GGATACAAGC TCAGCAGCTC CAAGGAGAAG CCCTTCATCA GATGCAAGCG 
TTATATGGCC AGCATTTTCC CATTGAGGTG CGGCATTATT TATCCCAGTG GATTGAAAGC
CAAGCATGGG ACTCAGTAGA TCTTGATAAT CCACAGGAGA ACATTAAGGC CACCCAGCTC
CTGGAGGGCC TGGTGCAGGA GCTGCAGAAG AAGGCAGAGC ACCAGGTGGG GGAAGATGGG
TTTTTACTGA AGATCAAGCT GGGGCACTAT GCCACACAGC TCCAGAACAC GTATGACCGC
TGCCCCATGG AGCTGGTCCG CTGCATCCGC CATATATTGT ACAATGAACA GAGGTTGGTC
CGAGAAGCCA ACAATGGTAG CTCTCCAGCT GGAAGCCTTG CTGATGCCAT GTCCCAGAAA
CACCTCCAGA TCAACCAGAC GTTTGAGGAG CTGCGACTGG TCACGCAGGA CACAGAGAAT
GAGTTAAAAA AGCTGCAGCA GACTCAGGAG TACTTCATCA TCCAGTACCA GGAGAGCCTG
AGGATCCAAG CTCAGTTTGG CCCGCTGGCC CAGCTGAGCC CCCAGGAGCG TCTGAGCCGG
GAGACGGCCC TCCAGCAGAA GCAGGTGTCT CTGGAGGCCT GGTTGCAGCG TGAGGCACAG
ACACTGCAGC AGTACCGCGT GGAGCTGGCC GAGAAGCACC AGAAGACCCT GCAGCTGCTG
CGGAAGCAGC AGACCATCAT CCTGGATGAC GAGCTGATCC AGTGGAAGCG GCGGCAGCAG
CTGGCCGGGA ACGGCGGGCC CCCCGAGGGC AGCCTGGACG TGCTACAGTC CTGGTGTGAG
AAGTTGGCCG AGATCATCTG GCAGAACCGG CAGCAGATCC GCAGGGCTGA GCACCTCTGC
CAGCAGCTGC CCATCCCCGG CCCAGTGGAG GAGATGCTGG CCGAGGTCAA CGCCACCATC
ACGGACATTA TCTCAGCCCT GGTGACCAGC ACGTTCATCA TTGAGAAGCA GCCTCCTCAG
GTCCTGAAGA CCCAGACCAA GTTTGCAGCC ACTGTGCGCC TGCTGGTGGG CGGGAAGCTG
AACGTGCACA TGAACCCCCC CCAGGTGAAG GCCACCATCA TCAGTGAGCA GCAGGCCAAG
TCTCTGCTCA AGAACGAGAA CACCCGCAAT GATTACAGTG GCGAGATCTT GAACAACTGC
TGCGTCATGG AGTACCACCA AGCCACAGGC ACCCTTAGTG CCCACTTCAG GAATATGTCC
CTGAAACGAA TTAAGAGGTC AGACCGTCGT GGGGCAGAGT CGGTGACAGA AGAAAAATTT
ACAATCCTGT TTGAATCCCA GTTCAGTGTT GGTGGAAATG AGCTGGTTTT TCAAGTCAAG
ACCCTGTCCC TGCCAGTGGT GGTGATCGTT CATGGCAGCC AGGACAACAA TGCGACGGCC
ACTGTTCTCT GGGACAATGC TTTTGCAGAG CCTGGCAGGG TGCCATTTGC CGTGCCTGAC
AAAGTGCTGT GGCCACAGCT GTGTGAGGCG CTCAACATGA AATTCAAGGC CGAAGTGCAG
AGCAACCGGG GCCTGACCAA GGAGAACCTC GTGTTCCTGG CGCAGAAACT GTTCAACAAC
AGCAGCAGCC ACCTGGAGGA CTACAGTGGC CTGTCTGTGT CCTGGTCCCA GTTCAACAGG
GAGAATTTAC CAGGACGGAA TTACACTTTC TGGCAATGGT TTGACGGTGT GATGGAAGTG
TTAAAAAAAC ATCTCAAGCC TCATTGGAAT GATGGGGCCA TTTTGGGGTT TGTAAACAAG
CAACAGGCCC ATGACCTACT CATTAACAAG CCAGATGGGA CCTTCCTCCT GAGATTCAGT
GACTCAGAAA TTGGCGGCAT CACCATTGCT TGGAAGTTTG ATTCTCAGGA AAGAATGTTT
TGGAATCTGA TGCCTTTTAC CACCAGAGAC TTCTCCATTC GGTCCCTAGC CGACCGCTTG
GGAGACTTGA ATTACCTTAT CTACGTGTTT CCTGATCGGC CAAAAGATGA AGTATACTCC
AAATACTACA CACCAGTTCC CTGCGAGTCT GCTACTGCTA AAGCTGTTGA TGGATACGTG
AAGCCACAGA TCAAGCAAGT GGTCCCTGAG TTTGTGAACG CATCTGCAGA TGCCGGGGGC
GGCAGCGCCA CGTACATGGA CCAGGCCCCC TCCCCAGCTG TGTGTCCCCA GGCTCACTAT
AACATGTACC CACAGAACCC TGACTCAGTC CTTGACACCG ATGGGGACTT CGATCTGGAG
GACACAATGG ACGTAGCGCG GCGTGTGGAG GAGCTCCTGG GCCGGCCAAT GGACAGTCAG
TGGATCCCGC ACGCACAATC GTGA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_036580.2
CDS170..2533
Misc Feature(1)164..166(+)
Misc Feature(2)173..547(+)
Misc Feature(3)548..550(+)
Misc Feature(4)551..553(+)
Misc Feature(5)581..1159(+)
Misc Feature(6)746..748(+)
Misc Feature(7)863..1132(+)
Misc Feature(8)1163..1918(+)
Misc Feature(9)1886..2320(+)
Misc Feature(10)1967..2101(+)
Misc Feature(11)2096..2146(+)
Misc Feature(12)2126..2281(+)
Misc Feature(13)2204..2206(+)
Misc Feature(14)2264..2266(+)
Misc Feature(15)2264..2266(+)
Misc Feature(16)2264..2266(+)
Misc Feature(17)2264..2266(+)
Misc Feature(18)2342..2344(+)
Misc Feature(19)2360..2362(+)
Misc Feature(20)2387..2389(+)
Misc Feature(21)2396..2398(+)
Exon (1)1..159
Gene:STAT5B
Gene Synonym:
Exon (2)160..297
Gene:STAT5B
Gene Synonym:
Exon (3)298..454
Gene:STAT5B
Gene Synonym:
Exon (4)455..544
Gene:STAT5B
Gene Synonym:
Exon (5)545..719
Gene:STAT5B
Gene Synonym:
Exon (6)720..850
Gene:STAT5B
Gene Synonym:
Exon (7)851..1002
Gene:STAT5B
Gene Synonym:
Exon (8)1003..1158
Gene:STAT5B
Gene Synonym:
Exon (9)1159..1338
Gene:STAT5B
Gene Synonym:
Exon (10)1339..1426
Gene:STAT5B
Gene Synonym:
Exon (11)1427..1549
Gene:STAT5B
Gene Synonym:
Exon (12)1550..1642
Gene:STAT5B
Gene Synonym:
Exon (13)1643..1849
Gene:STAT5B
Gene Synonym:
Exon (14)1850..1944
Gene:STAT5B
Gene Synonym:
Exon (15)1945..2075
Gene:STAT5B
Gene Synonym:
Exon (16)2076..2246
Gene:STAT5B
Gene Synonym:
Exon (17)2247..2298
Gene:STAT5B
Gene Synonym:
Exon (18)2299..2406
Gene:STAT5B
Gene Synonym:
Exon (19)2407..5094
Gene:STAT5B
Gene Synonym:
Translation
Position Chain Variation Link
34 34 c, t dbSNP:550574417
37 37 a, g dbSNP:535413649
100 100 -, gggcgggc dbSNP:539889607
160 160 a, g dbSNP:765106938
168 168 a, c dbSNP:754494821
171 171 c, t dbSNP:112572423
173 173 a, g dbSNP:113461014
176 176 a, g dbSNP:144024535
182 182 a, t dbSNP:376041480
202 202 a, g dbSNP:760427357
250 250 -, c dbSNP:34224133
268 268 c, t dbSNP:750016838
290 290 c, t dbSNP:767959957
308 308 a, g dbSNP:755543502
309 309 a, t dbSNP:750113759
324 324 a, t dbSNP:139130762
326 326 c, g dbSNP:762274331
331 331 c, t dbSNP:201916641
340 340 c, t dbSNP:200136266
342 342 c, t dbSNP:763601763
349 349 c, g dbSNP:200624718
350 350 c, t dbSNP:769947666
356 356 a, g dbSNP:759481948
366 366 a, g dbSNP:750520285
373 373 a, g dbSNP:776922169
397 397 g, t dbSNP:553370889
407 407 a, g dbSNP:747225467
416 416 c, t dbSNP:146176992
433 433 -, g dbSNP:746112176
439 439 c, t dbSNP:768410888
447 447 a, g dbSNP:749258998
449 449 c, t dbSNP:199645527
459 459 c, t dbSNP:766427008
460 460 a, g dbSNP:760931428
467 467 c, t dbSNP:199894785
484 484 g, t dbSNP:768466007
485 485 a, g dbSNP:748978416
497 497 c, t dbSNP:775502922
498 498 a, g dbSNP:769688321
499 499 a, c dbSNP:745807026
506 506 c, t dbSNP:780896511
513 513 a, g dbSNP:756794353
514 514 c, t dbSNP:576854811
524 524 c, t dbSNP:777518670
531 531 a, g dbSNP:758843144
539 539 a, g dbSNP:374711620
544 544 c, t dbSNP:555285694
558 558 c, t dbSNP:2277619
565 565 c, t dbSNP:770921312
572 572 a, g dbSNP:760681474
580 580 -, gtc dbSNP:764574191
592 592 c, t dbSNP:772912945
597 597 a, c dbSNP:771586939
598 598 c, g dbSNP:148793995
604 604 c, g dbSNP:778582220
609 609 a, c dbSNP:768919211
610 610 a, g dbSNP:144367484
617 617 a, g dbSNP:780393081
623 623 c, t dbSNP:121908502
624 624 a, c, g dbSNP:149614939
633 633 c, t dbSNP:138255473
634 634 a, g dbSNP:556691083
638 638 -, t dbSNP:35910895
643 643 a, g dbSNP:147066043
648 648 a, g dbSNP:764319884
651 651 a, g dbSNP:200923475
655 655 a, g dbSNP:759250756
669 669 a, c dbSNP:753748722
674 674 c, g dbSNP:759946844
694 694 a, g dbSNP:61755324
705 705 a, g dbSNP:376439732
729 729 c, g dbSNP:746169589
732 732 a, c, t dbSNP:143092033
733 733 a, g dbSNP:747457595
738 738 a, c dbSNP:777956676
744 744 c, t dbSNP:758519390
751 751 c, t dbSNP:748406387
768 768 a, g dbSNP:779220548
773 773 a, g dbSNP:755979362
777 777 c, t dbSNP:139065819
790 790 a, g dbSNP:563111908
794 794 c, g dbSNP:757272257
796 796 c, g dbSNP:751423677
806 806 g, t dbSNP:377601290
807 807 c, g dbSNP:762397922
819 819 a, g dbSNP:200900246
831 831 c, t dbSNP:764799602
833 833 c, t dbSNP:759101528
845 845 c, t dbSNP:777110652
847 847 c, t dbSNP:377043175
848 848 a, g dbSNP:761283639
859 859 c, t dbSNP:555155085
919 919 c, t dbSNP:764709139
956 956 a, g dbSNP:759281260
958 958 a, g dbSNP:753400820
964 964 c, t dbSNP:766796346
968 968 c, g dbSNP:760893128
989 989 a, g dbSNP:773861955
1018 1018 c, t dbSNP:771823136
1032 1032 a, t dbSNP:375808218
1038 1038 a, g dbSNP:376599040
1049 1049 c, t dbSNP:199982340
1050 1050 a, g dbSNP:754523154
1053 1053 a, g dbSNP:748817046
1064 1064 a, c dbSNP:779603963
1087 1087 a, c, t dbSNP:142321005
1097 1097 a, g dbSNP:750074223
1100 1100 a, g dbSNP:768028861
1106 1106 c, t dbSNP:757650048
1111 1111 c, t dbSNP:752128975
1113 1113 a, c dbSNP:572536541
1114 1114 a, g dbSNP:763508760
1120 1120 c, t dbSNP:372624709
1121 1121 a, g dbSNP:553989095
1132 1132 a, g dbSNP:759793357
1136 1136 a, g, t dbSNP:539091753
1161 1161 c, t dbSNP:753213429
1162 1162 a, g dbSNP:59491077
1166 1166 a, g dbSNP:759562375
1168 1168 c, t dbSNP:754071605
1170 1170 c, t dbSNP:754879860
1174 1174 a, g dbSNP:766656341
1187 1187 c, g dbSNP:760876362
1222 1222 c, t dbSNP:774063058
1225 1225 a, g dbSNP:768467135
1226 1226 c, t dbSNP:762833594
1227 1227 a, g dbSNP:143171571
1240 1240 c, t dbSNP:769445041
1241 1241 a, g dbSNP:745315653
1243 1243 a, g dbSNP:780841478
1252 1252 c, t dbSNP:770762035
1253 1253 a, g dbSNP:750053820
1256 1256 c, t dbSNP:778035877
1264 1264 c, t dbSNP:188781721
1266 1266 c, g dbSNP:753166147
1268 1268 a, c dbSNP:779416144
1270 1270 a, c dbSNP:61749920
1271 1271 -, c dbSNP:761761205
1271 1271 a, c, t dbSNP:144993426
1271 1271 -, c dbSNP:764965457
1281 1281 a, c dbSNP:28706683
1282 1282 c, t dbSNP:766426761
1309 1309 a, g dbSNP:760927580
1324 1324 c, t dbSNP:750619589
1326 1326 a, g dbSNP:202077096
1330 1330 c, t dbSNP:763821368
1331 1331 a, g dbSNP:199998167
1333 1333 c, t dbSNP:144060305
1345 1345 c, t dbSNP:780140449
1351 1351 c, t dbSNP:756173306
1372 1372 c, t dbSNP:200710135
1375 1375 c, t dbSNP:765486148
1388 1388 a, c dbSNP:767714314
1395 1395 c, t dbSNP:757419103
1401 1401 c, t dbSNP:752592229
1437 1437 a, g dbSNP:373996796
1457 1457 c, t dbSNP:781121963
1458 1458 a, g dbSNP:757544937
1466 1466 a, g dbSNP:751798472
1471 1471 a, g dbSNP:765151427
1504 1504 a, g dbSNP:111880437
1518 1518 g, t dbSNP:753839151
1553 1553 c, t dbSNP:770018533
1555 1555 a, g dbSNP:760116387
1561 1561 a, g dbSNP:776951968
1572 1572 c, t dbSNP:201911697
1606 1606 a, g dbSNP:775941580
1613 1613 a, g dbSNP:747016816
1624 1624 c, t dbSNP:777993133
1650 1650 a, t dbSNP:778265187
1660 1660 c, g dbSNP:772239606
1661 1661 a, g dbSNP:748404440
1671 1671 a, g dbSNP:146678334
1684 1684 a, g dbSNP:769636293
1698 1698 c, t dbSNP:200200711
1699 1699 a, g dbSNP:781030237
1720 1720 a, c, t dbSNP:373036522
1723 1723 a, g dbSNP:777292743
1724 1724 c, g dbSNP:757850017
1732 1732 c, t dbSNP:752406003
1734 1734 a, g dbSNP:764726823
1738 1738 a, c, g dbSNP:143172354
1750 1750 a, g dbSNP:140632704
1752 1752 a, g dbSNP:766828492
1759 1759 c, t dbSNP:761303284
1760 1760 a, g dbSNP:142918872
1773 1773 a, g dbSNP:375789837
1793 1793 a, g dbSNP:761733940
1802 1802 c, g dbSNP:569804189
1805 1805 a, g dbSNP:768821055
1806 1806 a, t dbSNP:749508222
1807 1807 a, g dbSNP:776333900
1813 1813 c, t dbSNP:139437059
1825 1825 c, t dbSNP:758513855
1835 1835 a, t dbSNP:777627496
1848 1848 a, g dbSNP:547984168
1859 1859 c, t dbSNP:561888537
1885 1885 a, g dbSNP:775637267
1894 1894 c, t dbSNP:75130700
1897 1897 c, t dbSNP:763332867
1914 1914 a, g dbSNP:374070270
1921 1921 c, t dbSNP:746737564
1924 1924 c, t dbSNP:572365056
1933 1933 c, t dbSNP:771960501
1990 1990 c, g dbSNP:1065376
1999 1999 a, g dbSNP:376254568
2008 2008 g, t dbSNP:765507952
2018 2018 c, t dbSNP:759739934
2023 2023 a, g dbSNP:773037490
2032 2032 c, t dbSNP:771869116
2041 2041 g, t dbSNP:144158108
2044 2044 c, t dbSNP:761686912
2052 2052 c, g dbSNP:774286856
2057 2057 c, g dbSNP:121908501
2075 2075 a, c dbSNP:367846125
2077 2077 a, g dbSNP:144106094
2096 2096 c, t dbSNP:150697956
2104 2104 g, t dbSNP:767238307
2111 2111 a, g dbSNP:761602572
2128 2128 c, t dbSNP:1057936
2130 2130 a, g dbSNP:201246187
2134 2134 c, t dbSNP:768697949
2140 2140 c, t dbSNP:141979661
2141 2141 a, g dbSNP:148568485
2160 2160 a, c dbSNP:370769279
2164 2164 c, t dbSNP:370257486
2173 2173 c, t dbSNP:147503881
2186 2186 c, t dbSNP:773533491
2187 2187 a, g dbSNP:776285574
2191 2191 a, g dbSNP:771200360
2205 2205 a, g dbSNP:747470866
2215 2215 c, t dbSNP:777984202
2228 2228 c, t dbSNP:758951069
2230 2230 c, t dbSNP:186347987
2234 2234 a, g dbSNP:778995803
2242 2242 c, t dbSNP:755002810
2253 2253 c, t dbSNP:200333924
2255 2255 a, g dbSNP:779977175
2257 2257 c, t dbSNP:756400339
2259 2259 a, g dbSNP:200738371
2266 2266 c, t dbSNP:369507540
2272 2272 a, g dbSNP:764006844
2284 2284 a, g dbSNP:753163911
2286 2286 a, t dbSNP:752681313
2287 2287 a, g dbSNP:777259731
2290 2290 a, g dbSNP:765329195
2299 2299 a, g dbSNP:781501709
2308 2308 c, t dbSNP:201825895
2309 2309 a, g dbSNP:752593400
2311 2311 a, g dbSNP:778825869
2317 2317 a, t dbSNP:754980286
2321 2321 a, g dbSNP:551009906
2323 2323 c, t dbSNP:143157773
2329 2329 c, t dbSNP:529306345
2330 2330 a, g dbSNP:750095303
2335 2335 c, t dbSNP:767216293
2340 2340 c, t dbSNP:139131471
2341 2341 a, g dbSNP:774739413
2347 2347 a, g dbSNP:768971207
2354 2354 g, t dbSNP:200042237
2384 2384 c, t dbSNP:372734271
2393 2393 a, g dbSNP:769925436
2399 2399 a, c dbSNP:745998088
2419 2419 c, t dbSNP:765726344
2426 2426 a, g dbSNP:760069627
2428 2428 c, t dbSNP:776893445
2430 2430 a, g dbSNP:372909572
2431 2431 c, g, t dbSNP:773512310
2434 2434 a, g dbSNP:368735480
2440 2440 c, t dbSNP:749104172
2451 2451 a, g dbSNP:779876449
2455 2455 a, g dbSNP:756044618
2461 2461 c, t dbSNP:146467656
2462 2462 a, g dbSNP:780699949
2467 2467 a, g dbSNP:756695652
2469 2469 a, g dbSNP:751214121
2472 2472 a, g dbSNP:763716770
2485 2485 c, t dbSNP:758060015
2493 2493 a, g dbSNP:138115420
2498 2498 a, g dbSNP:765607800
2503 2503 c, t dbSNP:760154055
2506 2506 c, t dbSNP:546587896
2513 2513 a, c dbSNP:777230664
2517 2517 c, t dbSNP:752309096
2521 2521 c, t dbSNP:375173590
2522 2522 a, g dbSNP:760771231
2527 2527 a, g dbSNP:568497349
2528 2528 c, t dbSNP:547016204
2529 2529 c, t dbSNP:748370281
2530 2530 a, g dbSNP:775177987
2535 2535 c, t dbSNP:375927948
2537 2537 c, t dbSNP:769580915
2538 2538 a, g dbSNP:371610966
2539 2539 c, t dbSNP:781038869
2540 2540 a, g dbSNP:527627852
2542 2542 c, t dbSNP:746576126
2544 2544 g, t dbSNP:560198087
2545 2545 c, t dbSNP:114275908
2558 2558 c, t dbSNP:752357162
2565 2565 g, t dbSNP:779170624
2567 2567 c, t dbSNP:2230097
2569 2569 a, c, t dbSNP:367656244
2582 2582 a, c dbSNP:767061487
2602 2602 c, t dbSNP:34320895
2605 2605 a, g dbSNP:755801250
2611 2611 c, t dbSNP:562669599
2631 2631 a, g dbSNP:543937773
2650 2650 a, g dbSNP:773901213
2703 2703 (tg)20, 22, 23 dbSNP:3222523
2716 2716 -, ttgt dbSNP:201167281
2717 2717 -, tgtg dbSNP:57573850
2717 2717 -, tg dbSNP:111734751
2718 2718 -, tt dbSNP:768754690
2719 2719 c, t dbSNP:573378468
2719 2719 -, t dbSNP:34396327
2720 2720 g, t dbSNP:1869364
2743 2743 -, tgtg dbSNP:770796002
2743 2743 -, tg dbSNP:770079556
2744 2744 -, gt dbSNP:397840818
2745 2745 -, tg dbSNP:146723548
2745 2745 c, t dbSNP:539831609
2746 2746 -, tg dbSNP:369424383
2757 2757 c, t dbSNP:180927761
2758 2758 a, g dbSNP:572099089
2774 2774 c, t dbSNP:190849391
2808 2808 a, g dbSNP:575762109
2864 2864 a, g dbSNP:75341760
2882 2882 c, t dbSNP:143357938
3005 3005 c, t dbSNP:568560438
3041 3041 c, t dbSNP:187214937
3076 3076 c, t dbSNP:756745694
3082 3082 c, t dbSNP:535021090
3084 3084 c, t dbSNP:114475755
3121 3121 c, t dbSNP:181812855
3139 3139 g, t dbSNP:533239913
3154 3154 a, g dbSNP:568985190
3168 3168 c, t dbSNP:549000823
3180 3180 a, t dbSNP:765673447
3217 3217 c, t dbSNP:755565616
3221 3221 c, t dbSNP:754196319
3233 3233 a, g dbSNP:528994237
3237 3237 a, g dbSNP:766769074
3266 3266 g, t dbSNP:561454695
3278 3278 -, at dbSNP:773623045
3314 3314 a, g dbSNP:117074548
3319 3319 c, t dbSNP:750676055
3322 3322 c, g dbSNP:528094698
3337 3337 a, g dbSNP:569658173
3356 3356 c, g dbSNP:139332839
3402 3402 c, t dbSNP:761815470
3427 3427 c, t dbSNP:113824843
3428 3428 a, g dbSNP:146827392
3455 3455 a, g dbSNP:774551681
3468 3468 a, g dbSNP:557630320
3474 3474 g, t dbSNP:542452702
3475 3475 c, t dbSNP:575040646
3502 3502 g, t dbSNP:553526475
3554 3554 c, t dbSNP:781180792
3560 3560 a, g dbSNP:535083491
3563 3563 c, g dbSNP:141028136
3628 3628 a, t dbSNP:148224780
3637 3637 c, t dbSNP:539396877
3642 3642 c, t dbSNP:768477548
3678 3678 c, t dbSNP:569123522
3708 3708 c, t dbSNP:78682061
3730 3730 a, c dbSNP:190178825
3745 3745 a, g dbSNP:775399441
3769 3769 a, g dbSNP:567884387
3775 3775 -, g dbSNP:35987392
3788 3788 a, g dbSNP:546302398
3817 3817 c, t dbSNP:143058452
3819 3819 a, g dbSNP:769730435
3835 3835 c, t dbSNP:376858672
3836 3836 a, g dbSNP:563975009
3879 3879 a, g dbSNP:747203679
3889 3889 a, g dbSNP:545777471
3899 3899 c, g dbSNP:549947506
3908 3908 c, t dbSNP:563976387
3929 3929 c, t dbSNP:780994364
3930 3930 a, g dbSNP:770415612
3931 3931 g, t dbSNP:116244359
3937 3937 a, g dbSNP:575102422
3948 3948 c, t dbSNP:553589699
3955 3955 c, t dbSNP:746486622
3956 3956 a, g dbSNP:541195855
3988 3988 c, t dbSNP:577264997
4044 4044 a, t dbSNP:558721369
4070 4070 a, g dbSNP:184810925
4080 4080 -, t dbSNP:34694406
4093 4093 a, g dbSNP:373852784
4095 4095 -, a dbSNP:528234693
4147 4147 a, g dbSNP:116906338
4175 4175 a, g dbSNP:149034065
4178 4178 a, t dbSNP:556577422
4179 4179 -, attt dbSNP:770152434
4179 4179 a, g dbSNP:181312613
4195 4195 c, t dbSNP:111883304
4222 4222 c, g, t dbSNP:112972196
4296 4296 a, g dbSNP:780358197
4298 4298 a, g dbSNP:188617884
4300 4300 c, t dbSNP:564340503
4301 4301 a, g dbSNP:756476830
4309 4309 g, t dbSNP:538575383
4365 4365 c, t dbSNP:750588480
4366 4366 a, g dbSNP:767622858
4407 4407 c, t dbSNP:762164467
4430 4430 a, g dbSNP:551942072
4434 4434 c, g dbSNP:530550813
4436 4436 g, t dbSNP:146438448
4459 4459 c, g dbSNP:548933669
4465 4465 g, t dbSNP:145236827
4473 4473 c, t dbSNP:751566413
4492 4492 a, g dbSNP:547241866
4510 4510 a, g dbSNP:183533045
4543 4543 a, g dbSNP:779546182
4634 4634 a, g dbSNP:757776699
4668 4668 c, t dbSNP:191284679
4670 4670 c, t dbSNP:754414220
4677 4677 c, t dbSNP:767007096
4679 4679 c, t dbSNP:188882610
4701 4701 c, t dbSNP:113234237
4721 4721 a, c dbSNP:140444425
4746 4746 a, c dbSNP:543521202
4778 4778 c, t dbSNP:576042434
4785 4785 c, t dbSNP:764287553
4801 4801 c, t dbSNP:185708008
4845 4845 c, t dbSNP:762930453
4851 4851 c, g, t dbSNP:59138731
4852 4852 a, g dbSNP:146750609
4892 4892 c, t dbSNP:15456
4898 4898 a, c dbSNP:535386024
4920 4920 c, g dbSNP:149725455
4960 4960 a, c dbSNP:1046104
4967 4967 a, g dbSNP:527587051
4991 4991 c, t dbSNP:769643619
5011 5011 -, a dbSNP:373091385

Target ORF information:

RefSeq Version NM_012448
Organism Homo sapiens (human)
Definition Homo sapiens signal transducer and activator of transcription 5B (STAT5B), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_012448

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
ATGGCTGTGT GGATACAAGC TCAGCAGCTC CAAGGAGAAG CCCTTCATCA GATGCAAGCG 
TTATATGGCC AGCATTTTCC CATTGAGGTG CGGCATTATT TATCCCAGTG GATTGAAAGC
CAAGCATGGG ACTCAGTAGA TCTTGATAAT CCACAGGAGA ACATTAAGGC CACCCAGCTC
CTGGAGGGCC TGGTGCAGGA GCTGCAGAAG AAGGCAGAGC ACCAGGTGGG GGAAGATGGG
TTTTTACTGA AGATCAAGCT GGGGCACTAT GCCACACAGC TCCAGAACAC GTATGACCGC
TGCCCCATGG AGCTGGTCCG CTGCATCCGC CATATATTGT ACAATGAACA GAGGTTGGTC
CGAGAAGCCA ACAATGGTAG CTCTCCAGCT GGAAGCCTTG CTGATGCCAT GTCCCAGAAA
CACCTCCAGA TCAACCAGAC GTTTGAGGAG CTGCGACTGG TCACGCAGGA CACAGAGAAT
GAGTTAAAAA AGCTGCAGCA GACTCAGGAG TACTTCATCA TCCAGTACCA GGAGAGCCTG
AGGATCCAAG CTCAGTTTGG CCCGCTGGCC CAGCTGAGCC CCCAGGAGCG TCTGAGCCGG
GAGACGGCCC TCCAGCAGAA GCAGGTGTCT CTGGAGGCCT GGTTGCAGCG TGAGGCACAG
ACACTGCAGC AGTACCGCGT GGAGCTGGCC GAGAAGCACC AGAAGACCCT GCAGCTGCTG
CGGAAGCAGC AGACCATCAT CCTGGATGAC GAGCTGATCC AGTGGAAGCG GCGGCAGCAG
CTGGCCGGGA ACGGCGGGCC CCCCGAGGGC AGCCTGGACG TGCTACAGTC CTGGTGTGAG
AAGTTGGCCG AGATCATCTG GCAGAACCGG CAGCAGATCC GCAGGGCTGA GCACCTCTGC
CAGCAGCTGC CCATCCCCGG CCCAGTGGAG GAGATGCTGG CCGAGGTCAA CGCCACCATC
ACGGACATTA TCTCAGCCCT GGTGACCAGC ACGTTCATCA TTGAGAAGCA GCCTCCTCAG
GTCCTGAAGA CCCAGACCAA GTTTGCAGCC ACTGTGCGCC TGCTGGTGGG CGGGAAGCTG
AACGTGCACA TGAACCCCCC CCAGGTGAAG GCCACCATCA TCAGTGAGCA GCAGGCCAAG
TCTCTGCTCA AGAACGAGAA CACCCGCAAT GATTACAGTG GCGAGATCTT GAACAACTGC
TGCGTCATGG AGTACCACCA AGCCACAGGC ACCCTTAGTG CCCACTTCAG GAATATGTCC
CTGAAACGAA TTAAGAGGTC AGACCGTCGT GGGGCAGAGT CGGTGACAGA AGAAAAATTT
ACAATCCTGT TTGAATCCCA GTTCAGTGTT GGTGGAAATG AGCTGGTTTT TCAAGTCAAG
ACCCTGTCCC TGCCAGTGGT GGTGATCGTT CATGGCAGCC AGGACAACAA TGCGACGGCC
ACTGTTCTCT GGGACAATGC TTTTGCAGAG CCTGGCAGGG TGCCATTTGC CGTGCCTGAC
AAAGTGCTGT GGCCACAGCT GTGTGAGGCG CTCAACATGA AATTCAAGGC CGAAGTGCAG
AGCAACCGGG GCCTGACCAA GGAGAACCTC GTGTTCCTGG CGCAGAAACT GTTCAACAAC
AGCAGCAGCC ACCTGGAGGA CTACAGTGGC CTGTCTGTGT CCTGGTCCCA GTTCAACAGG
GAGAATTTAC CAGGACGGAA TTACACTTTC TGGCAATGGT TTGACGGTGT GATGGAAGTG
TTAAAAAAAC ATCTCAAGCC TCATTGGAAT GATGGGGCCA TTTTGGGGTT TGTAAACAAG
CAACAGGCCC ATGACCTACT CATTAACAAG CCAGATGGGA CCTTCCTCCT GAGATTCAGT
GACTCAGAAA TTGGCGGCAT CACCATTGCT TGGAAGTTTG ATTCTCAGGA AAGAATGTTT
TGGAATCTGA TGCCTTTTAC CACCAGAGAC TTCTCCATTC GGTCCCTAGC CGACCGCTTG
GGAGACTTGA ATTACCTTAT CTACGTGTTT CCTGATCGGC CAAAAGATGA AGTATACTCC
AAATACTACA CACCAGTTCC CTGCGAGTCT GCTACTGCTA AAGCTGTTGA TGGATACGTG
AAGCCACAGA TCAAGCAAGT GGTCCCTGAG TTTGTGAACG CATCTGCAGA TGCCGGGGGC
GGCAGCGCCA CGTACATGGA CCAGGCCCCC TCCCCAGCTG TGTGTCCCCA GGCTCACTAT
AACATGTACC CACAGAACCC TGACTCAGTC CTTGACACCG ATGGGGACTT CGATCTGGAG
GACACAATGG ACGTAGCGCG GCGTGTGGAG GAGCTCCTGG GCCGGCCAAT GGACAGTCAG
TGGATCCCGC ACGCACAATC GTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.