The following ACTC1 gene sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ACTC1 gene which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
||ORF Nucleotide Sequence (Length: 1134bp)
||pcDNA3.1+/C-(K)DYK or customized vector
|Tag on pcDNA3.1+/C-(K)DYK
||C terminal DYKDDDDK tags
|ORF Insert Method
||CloneEZ® Seamless cloning technology
||Homo sapiens (human)
||actin, alpha cardiac muscle 1 proprotein
||REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from DB504220.1, BC009978.2,
AK056592.1, CR737466.1 and AI222203.1.
This sequence is a reference standard in the RefSeqGene project.
On Aug 31, 2006 this sequence version replaced gi:46411161.
Summary: Actins are highly conserved proteins that are involved in
various types of cell motility. Polymerization of globular actin
(G-actin) leads to a structural filament (F-actin) in the form of a
two-stranded helix. Each actin can bind to four others. The protein
encoded by this gene belongs to the actin family which is comprised
of three main groups of actin isoforms, alpha, beta, and gamma. The
alpha actins are found in muscle tissues and are a major
constituent of the contractile apparatus. Defects in this gene have
been associated with idiopathic dilated cardiomyopathy (IDC) and
familial hypertrophic cardiomyopathy (FHC). [provided by RefSeq,
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
Transcript exon combination :: BC009978.2, AK129902.1 [ECO:0000332]
RNAseq introns :: single sample supports all introns
COMPLETENESS: complete on the 3' end.