The following TECTA gene sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TECTA gene which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
||ORF Nucleotide Sequence (Length: 6468bp)
||pcDNA3.1+/C-(K)DYK or customized vector
|Tag on pcDNA3.1+/C-(K)DYK
||C terminal DYKDDDDK tags
|ORF Insert Method
||CloneEZ® Seamless cloning technology
||Homo sapiens (human)
||REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from AP000646.4 and AP000826.5.
This sequence is a reference standard in the RefSeqGene project.
On Mar 29, 2007 this sequence version replaced gi:4885626.
Summary: The tectorial membrane is an extracellular matrix of the
inner ear that contacts the stereocilia bundles of specialized
sensory hair cells. Sound induces movement of these hair cells
relative to the tectorial membrane, deflects the stereocilia, and
leads to fluctuations in hair-cell membrane potential, transducing
sound into electrical signals. Alpha-tectorin is one of the major
noncollagenous components of the tectorial membrane. Mutations in
the TECTA gene have been shown to be responsible for autosomal
dominant nonsyndromic hearing impairment and a recessive form of
sensorineural pre-lingual non-syndromic deafness. [provided by
RefSeq, Jul 2008].
Sequence Note: The RefSeq transcript and protein were derived from
genomic sequence to make the sequence consistent with the reference
genome assembly. The genomic coordinates used for the transcript
record were based on transcript alignments and orthologous data.
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
RNAseq introns :: mixed/partial sample support SAMEA2161674