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TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) [Homo sapiens (human)]

Gene Symbol TFAP2A
Entrez Gene ID 7020
Full Name transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
Synonyms AP-2, AP-2alpha, AP2TF, BOFS, TFAP2
General protein information
Preferred Names
transcription factor AP-2-alpha
Names
transcription factor AP-2-alpha
AP2-alpha
activator protein 2
AP-2 transcription factor
activating enhancer-binding protein 2-alpha
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

6

6p24

Summary The protein encoded by this gene is a transcription factor that binds the consensus sequence 5'-GCCNNNGGC-3'. The encoded protein functions as either a homodimer or as a heterodimer with similar family members. This protein activates the transcription of some genes while inhibiting the transcription of others. Defects in this gene are a cause of branchiooculofacial syndrome (BOFS). Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Dec 2009]. lac of sum
Disorder MIM:

107580

Disorder Html: Branchiooculofacial syndrome, 113620 (3)





The following TFAP2A gene sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TFAP2A gene which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu40448 XM_006715175 PREDICTED: Homo sapiens transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) (TFAP2A), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $319
OHu60957 XM_011514833 PREDICTED: Homo sapiens transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) (TFAP2A), transcript variant X2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $319
OHu16263 NM_003220 Homo sapiens transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) (TFAP2A), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $369
OHu16217 NM_001032280 Homo sapiens transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) (TFAP2A), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $379
OHu19280 NM_001042425 Homo sapiens transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) (TFAP2A), transcript variant 3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $359

*Business Day
**You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.


CloneID OHu40448
Accession Version XM_006715175.2
Sequence Information ORF Nucleotide Sequence (Length: 1449bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product transcription factor AP-2-alpha isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_007592.16) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 12, 2015 this sequence version replaced gi:578811884. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
ATGGAGGAGC CGCGCAGCAG CGGGCAGCCG AGTCCCGAGT CCCAGACTCG GCTGCGAAGC 
GGCGGAGCCC GCGGCCAGAC AGGGCCGGGA AGCGCCTGCC GCGCCGAGAG CCCCACGAGC
GCCCGGACGC GGTCCCAAGC AGCTCCTACC CGCTACGCAC GACCCCCGCT GCATCCCGAG
GACCGTCACG ACGGCACCAG CAACGGGACG GCACGGTTGC CCCAGCTGGG CACTGTAGGT
CAATCTCCCT ACACGAGCGC CCCGCCGCTG TCCCACACCC CCAATGCCGA CTTCCAGCCC
CCATACTTCC CCCCACCCTA CCAGCCTATC TACCCCCAGT CGCAAGATCC TTACTCCCAC
GTCAACGACC CCTACAGCCT GAACCCCCTG CACGCCCAGC CGCAGCCGCA GCACCCAGGC
TGGCCCGGCC AGAGGCAGAG CCAGGAGTCT GGGCTCCTGC ACACGCACCG GGGGCTGCCT
CACCAGCTGT CGGGCCTGGA TCCTCGCAGG GACTACAGGC GGCACGAGGA CCTCCTGCAC
GGCCCACACG CGCTCAGCTC AGGACTCGGA GACCTCTCGA TCCACTCCTT ACCTCACGCC
ATCGAGGAGG TCCCGCATGT AGAAGACCCG GGTATTAACA TCCCAGATCA AACTGTAATT
AAGAAAGGCC CCGTGTCCCT GTCCAAGTCC AACAGCAATG CCGTCTCCGC CATCCCTATT
AACAAGGACA ACCTCTTCGG CGGCGTGGTG AACCCCAACG AAGTCTTCTG TTCAGTTCCG
GGTCGCCTCT CGCTCCTCAG CTCCACCTCG AAGTACAAGG TCACGGTGGC GGAAGTGCAG
CGGCGGCTCT CACCACCCGA GTGTCTCAAC GCGTCGCTGC TGGGCGGAGT GCTCCGGAGG
GCGAAGTCTA AAAATGGAGG AAGATCTTTA AGAGAAAAAC TGGACAAAAT AGGATTAAAT
CTGCCTGCAG GGAGACGTAA AGCTGCCAAC GTTACCCTGC TCACATCACT AGTAGAGGGA
GAAGCTGTCC ACCTAGCCAG GGACTTTGGG TACGTGTGCG AAACCGAATT TCCTGCCAAA
GCAGTAGCTG AATTTCTCAA CCGACAACAT TCCGATCCCA ATGAGCAAGT GACAAGAAAA
AACATGCTCC TGGCTACAAA ACAGATATGC AAAGAGTTCA CCGACCTGCT GGCTCAGGAC
CGATCTCCCC TGGGGAACTC ACGGCCCAAC CCCATCCTGG AGCCCGGCAT CCAGAGCTGC
TTGACCCACT TCAACCTCAT CTCCCACGGC TTCGGCAGCC CCGCGGTGTG TGCCGCGGTC
ACGGCCCTGC AGAACTATCT CACCGAGGCC CTCAAGGCCA TGGACAAAAT GTACCTCAGC
AACAACCCCA ACAGCCACAC GGACAACAAC GCCAAAAGCA GTGACAAAGA GGAGAAGCAC
AGAAAGTGA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqXP_006715238.1
CDS94..1542
Misc Feature(1)853..1470(+)
Translation
Position Chain Variation Link
10 10 a, g dbSNP:773727736
15 15 c, t dbSNP:537427875
25 25 a, c dbSNP:148848645
26 26 a, t dbSNP:554807479
51 51 a, g dbSNP:6456450
87 87 c, g dbSNP:2763142
138 138 a, g dbSNP:775207343
187 187 c, g dbSNP:575010603
206 206 c, t dbSNP:771855642
210 210 a, g dbSNP:745726205
217 217 c, g dbSNP:774255741
227 227 c, t dbSNP:770947323
260 260 a, c dbSNP:376909867
261 261 a, g dbSNP:749291059
287 287 a, g, t dbSNP:143258135
309 309 a, g dbSNP:768948369
325 325 a, g dbSNP:9368354
329 329 g, t dbSNP:780216169
332 332 g, t dbSNP:772479857
333 333 g, t dbSNP:746272068
338 338 c, t dbSNP:779448987
339 339 a, t dbSNP:757798850
348 348 g, t dbSNP:752157129
352 352 g, t dbSNP:373246714
361 361 c, t dbSNP:754562525
362 362 c, t dbSNP:751224702
363 363 a, g dbSNP:149126243
368 368 a, c dbSNP:762787739
370 370 a, c dbSNP:750226796
371 371 c, g dbSNP:765183722
374 374 c, t dbSNP:761863117
375 375 -, cc dbSNP:753073720
376 376 a, c dbSNP:776792762
377 377 a, g dbSNP:527785340
379 379 c, g dbSNP:760904143
383 383 a, c dbSNP:775764363
385 385 c, t dbSNP:772228476
388 388 -, a dbSNP:34436436
393 393 c, t dbSNP:746209784
396 396 a, c dbSNP:779173083
399 399 c, t dbSNP:771371649
401 401 c, t dbSNP:749803917
407 407 a, c dbSNP:778321721
408 408 a, c dbSNP:754476051
413 413 a, c dbSNP:746550070
417 417 a, g dbSNP:779727040
425 425 a, g dbSNP:758018662
430 430 c, g dbSNP:750185451
435 435 a, g dbSNP:765135263
441 441 a, t dbSNP:560684169
442 442 a, c dbSNP:753822419
448 448 a, t dbSNP:764184708
450 450 c, g dbSNP:760782033
459 459 c, g dbSNP:775468691
468 468 c, t dbSNP:767736500
479 479 c, t dbSNP:200131527
480 480 c, t dbSNP:774713482
481 481 c, g dbSNP:376101872
486 486 a, c, t dbSNP:545067807
495 495 a, g dbSNP:773687604
501 501 a, g dbSNP:770326832
517 517 c, t dbSNP:746489683
518 518 c, t dbSNP:779455245
519 519 c, g dbSNP:758008816
525 525 c, g dbSNP:372468982
527 527 c, g dbSNP:778774564
534 534 c, g dbSNP:757104358
544 544 c, g dbSNP:753730365
550 550 c, t dbSNP:764088571
551 551 a, t dbSNP:756034130
564 564 a, g dbSNP:138225261
565 565 a, g dbSNP:767502053
568 568 c, t dbSNP:563009991
582 582 a, g dbSNP:544933565
585 585 a, g dbSNP:766641930
599 599 g, t dbSNP:763273543
600 600 a, c dbSNP:145673154
606 606 c, g dbSNP:200574824
607 607 c, t dbSNP:748618587
608 608 a, g dbSNP:774997299
618 618 a, c dbSNP:771478009
633 633 c, t dbSNP:745441531
642 642 a, c dbSNP:778686750
644 644 a, c dbSNP:770743434
647 647 c, t dbSNP:111353850
648 648 c, t dbSNP:369051842
657 657 a, g dbSNP:777729482
663 663 a, c dbSNP:756019412
672 672 g, t dbSNP:747353442
678 678 c, t dbSNP:752575373
680 680 c, g dbSNP:555997980
689 689 a, t dbSNP:754995203
690 690 c, t dbSNP:375321728
694 694 a, g dbSNP:751678511
702 702 a, g dbSNP:766548263
711 711 c, t dbSNP:758551492
712 712 a, g dbSNP:540208578
719 719 a, g dbSNP:111681798
722 722 a, c dbSNP:765549775
723 723 a, g dbSNP:762057151
725 725 a, g dbSNP:754264393
729 729 g, t dbSNP:528101301
756 756 a, g dbSNP:559183946
765 765 c, g dbSNP:531975577
773 773 c, t dbSNP:764532449
776 776 a, c dbSNP:146735451
780 780 -, gtccaa dbSNP:771955798
784 784 a, g dbSNP:201296512
791 791 a, g dbSNP:565071190
801 801 c, t dbSNP:143363077
805 805 a, g dbSNP:772810778
808 808 c, t dbSNP:764751482
813 813 g, t dbSNP:761543465
819 819 a, g dbSNP:372587710
823 823 a, g dbSNP:768437372
828 828 c, t dbSNP:746862188
831 831 a, c, t dbSNP:772033707
834 834 a, c dbSNP:745892262
836 836 a, g dbSNP:763437712
851 851 a, g dbSNP:202002859
856 856 c, g dbSNP:749528750
858 858 c, g dbSNP:777922831
879 879 c, t dbSNP:756526526
882 882 c, t dbSNP:369302647
901 901 c, t dbSNP:768098328
903 903 a, g dbSNP:755569103
913 913 a, g dbSNP:749849069
915 915 c, g dbSNP:764811179
936 936 a, g dbSNP:761298686
937 937 c, g dbSNP:151344524
938 938 a, c, g dbSNP:151344525
939 939 a, g dbSNP:554807432
945 945 a, c dbSNP:763782805
951 951 a, c, g dbSNP:140905560
952 952 a, g dbSNP:151344526
954 954 a, g dbSNP:151009833
980 980 a, g dbSNP:151344527
987 987 c, g, t dbSNP:142511319
988 988 c, g, t dbSNP:151344528
989 989 c, g dbSNP:151344530
991 991 a, c, g dbSNP:121909574
995 995 c, t dbSNP:151344531
1013 1013 a, g dbSNP:121909575
1019 1019 c, t dbSNP:781630462
1021 1021 c, t dbSNP:769053661
1027 1027 c, g dbSNP:747379877
1033 1033 c, g dbSNP:758652364
1048 1048 c, t dbSNP:35008125
1054 1054 c, t dbSNP:758856518
1080 1080 c, t dbSNP:753291798
1083 1083 c, t dbSNP:777278396
1084 1084 a, g dbSNP:755697313
1093 1093 c, t dbSNP:750843820
1114 1114 a, g dbSNP:267607108
1119 1119 c, t dbSNP:771879686
1131 1131 a, c dbSNP:745607212
1140 1140 c, t dbSNP:369463773
1143 1143 a, g dbSNP:778860533
1146 1146 c, t dbSNP:141711078
1147 1147 a, g dbSNP:377114324
1152 1152 c, t dbSNP:771617050
1153 1153 a, g dbSNP:756122879
1157 1157 c, t dbSNP:752860081
1160 1160 a, c dbSNP:144275164
1176 1176 a, c dbSNP:767678528
1191 1191 c, t dbSNP:1803117
1193 1193 a, g dbSNP:759768857
1199 1199 a, g dbSNP:751854479
1200 1200 a, g dbSNP:766726105
1203 1203 g, t dbSNP:763437006
1207 1207 a, g dbSNP:575186761
1215 1215 c, t dbSNP:770375179
1243 1243 c, t dbSNP:760066655
1254 1254 a, g dbSNP:758672228
1255 1255 c, g dbSNP:750693033
1260 1260 a, g dbSNP:765634102
1271 1271 a, t dbSNP:757626207
1272 1272 c, t dbSNP:754379873
1275 1275 c, t dbSNP:140377026
1285 1285 a, g dbSNP:759083592
1293 1293 c, t dbSNP:774029144
1294 1294 c, g dbSNP:9350373
1295 1295 g, t dbSNP:765898042
1296 1296 a, g dbSNP:762671343
1300 1300 c, t dbSNP:772807658
1302 1302 c, t dbSNP:375372321
1310 1310 a, g dbSNP:747986718
1322 1322 a, g dbSNP:776521790
1338 1338 c, t dbSNP:372082918
1352 1352 a, g dbSNP:768613709
1358 1358 c, t dbSNP:747045958
1368 1368 c, t dbSNP:780192295
1371 1371 c, t dbSNP:372299435
1374 1374 c, t dbSNP:550611281
1386 1386 c, t dbSNP:779059756
1398 1398 a, g dbSNP:757618280
1403 1403 a, g dbSNP:754293607
1405 1405 g, t dbSNP:778384375
1407 1407 c, g, t dbSNP:181105841
1410 1410 g, t dbSNP:765909703
1413 1413 c, g dbSNP:762430867
1414 1414 a, t dbSNP:750068981
1416 1416 c, g, t dbSNP:2230116
1434 1434 c, g dbSNP:200847258
1437 1437 c, t dbSNP:201494266
1476 1476 -, ctcagcaac dbSNP:760836149
1484 1484 a, c dbSNP:201591227
1485 1485 c, t dbSNP:3734391
1487 1487 a, g dbSNP:772175937
1491 1491 c, t dbSNP:745981703
1495 1495 a, c, g dbSNP:771307700
1503 1503 a, c dbSNP:749620758
1505 1505 c, t dbSNP:1803116
1511 1511 a, g dbSNP:778294642
1513 1513 a, g dbSNP:756614321
1524 1524 a, g dbSNP:374310228
1525 1525 -, gag dbSNP:773291481
1525 1525 a, g dbSNP:781601001
1544 1544 a, g dbSNP:757896248
1546 1546 c, t dbSNP:749936793
1547 1547 c, g dbSNP:764897160
1548 1548 c, t dbSNP:761472794
1549 1549 c, t dbSNP:753566744
1551 1551 c, t dbSNP:763868660
1552 1552 c, g dbSNP:760518852
1554 1554 -, c dbSNP:767561818
1554 1554 c, t dbSNP:775472363
1561 1561 c, t dbSNP:771942212
1566 1566 c, t dbSNP:371339437
1568 1568 a, c dbSNP:552520811
1571 1571 a, g dbSNP:771219549
1578 1578 -, cc dbSNP:761920926
1581 1581 c, t dbSNP:749517602
1582 1582 c, t dbSNP:778198576
1583 1583 a, c dbSNP:770263013
1585 1585 c, t dbSNP:748502364
1586 1586 a, c dbSNP:781698007
1586 1586 -, c dbSNP:774267757
1591 1591 a, g dbSNP:755465363
1595 1595 a, c dbSNP:530677405
1600 1600 c, t dbSNP:563344990
1608 1608 g, t dbSNP:542047656
1623 1623 c, t dbSNP:369680359
1626 1626 a, c dbSNP:574832806
1630 1630 a, c dbSNP:10456013
1634 1634 c, t dbSNP:541008118
1668 1668 c, t dbSNP:764664664
1669 1669 c, g dbSNP:188674648
1670 1670 a, g dbSNP:759057111
1680 1680 a, c dbSNP:558781203
1681 1681 c, t dbSNP:1461010
1692 1692 a, c dbSNP:576370374
1708 1708 g, t dbSNP:554863655
1785 1785 c, t dbSNP:536878759
1839 1839 a, g dbSNP:118042860
1865 1865 -, t dbSNP:34512481
1874 1874 -, t dbSNP:111823522
1875 1875 -, t dbSNP:546903889
1879 1879 a, c dbSNP:2763172
1884 1884 a, c dbSNP:201528167
1885 1885 a, t dbSNP:546690434
1901 1901 -, caa dbSNP:397885453
1912 1912 -, caa dbSNP:776813404
1913 1913 -, caa dbSNP:34426547
1927 1927 c, t dbSNP:9350372
1943 1943 a, g dbSNP:534571057
1955 1955 -, aaaaa dbSNP:560622395
1960 1960 a, t dbSNP:762265236
1974 1974 c, t dbSNP:570465051
1985 1985 c, t dbSNP:552459189
2001 2001 a, g dbSNP:151315569
2040 2040 -, aaaaa dbSNP:544361557
2055 2055 a, g dbSNP:146797011
2076 2076 a, c dbSNP:1045385
2112 2112 a, c dbSNP:548057203
2135 2135 a, g dbSNP:770745416
2138 2138 g, t dbSNP:749647128
2155 2155 a, c dbSNP:184322632
2159 2159 g, t dbSNP:529930646
2168 2168 -, g dbSNP:540540292
2174 2174 -, t dbSNP:773862113
2176 2176 a, t dbSNP:559552401
2192 2192 a, g dbSNP:201450721
2204 2204 a, g dbSNP:541132655
2217 2217 c, g dbSNP:576308493
2220 2220 a, g dbSNP:75419063
2243 2243 a, t dbSNP:564928565
2254 2254 a, g dbSNP:543460673
2270 2270 a, g dbSNP:181681871
2281 2281 g, t dbSNP:147713410
2286 2286 c, t dbSNP:201819112
2287 2287 -, t dbSNP:397965898
2288 2288 c, t dbSNP:74636495
2296 2296 c, t dbSNP:542820219
2297 2297 -, t dbSNP:61569279
2298 2298 -, t dbSNP:546035279
2298 2298 a, t dbSNP:78186274
2316 2316 c, t dbSNP:572623022
2342 2342 a, c dbSNP:574855862
2393 2393 g, t dbSNP:3088288
2397 2397 g, t dbSNP:2763171
2402 2402 a, g dbSNP:770287660
2409 2409 -, t dbSNP:768958142
2422 2422 g, t dbSNP:115631304
2467 2467 a, g dbSNP:2763170
2486 2486 a, g dbSNP:113256477
2497 2497 a, g dbSNP:185414193
2536 2536 c, t dbSNP:558581973
2544 2544 a, c dbSNP:537069740
2550 2550 a, g dbSNP:773868091
2555 2555 a, g dbSNP:781574382
2561 2561 c, g dbSNP:569833793
2624 2624 a, c dbSNP:755049370
2630 2630 g, t dbSNP:2857059
2632 2632 a, t dbSNP:2857060
2651 2651 c, t dbSNP:11553434
2661 2661 c, t dbSNP:747101844
2670 2670 a, c dbSNP:545023610
2701 2701 a, g dbSNP:80094467
2710 2710 a, g dbSNP:780237615
2715 2715 -, ct dbSNP:554956373
2716 2716 c, t dbSNP:193259940
2731 2731 -, tc dbSNP:150236619
2769 2769 a, g dbSNP:2763169
2772 2772 c, t dbSNP:758681260
2843 2843 c, t dbSNP:753621983
2847 2847 -, agt dbSNP:769945457
2856 2856 g, t dbSNP:186469860
2889 2889 a, g dbSNP:573067252
2921 2921 -, t dbSNP:398094002
2929 2929 -, t dbSNP:79168174
2953 2953 c, g dbSNP:763807060
3038 3038 a, g dbSNP:745977233
3065 3065 a, c dbSNP:2763168
3085 3085 g, t dbSNP:752628820
3130 3130 a, g dbSNP:552923535
3166 3166 a, g dbSNP:16893358
3192 3192 -, ttgt dbSNP:372257234

Target ORF information:

RefSeq Version XM_006715175
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) (TFAP2A), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_006715175

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
ATGGAGGAGC CGCGCAGCAG CGGGCAGCCG AGTCCCGAGT CCCAGACTCG GCTGCGAAGC 
GGCGGAGCCC GCGGCCAGAC AGGGCCGGGA AGCGCCTGCC GCGCCGAGAG CCCCACGAGC
GCCCGGACGC GGTCCCAAGC AGCTCCTACC CGCTACGCAC GACCCCCGCT GCATCCCGAG
GACCGTCACG ACGGCACCAG CAACGGGACG GCACGGTTGC CCCAGCTGGG CACTGTAGGT
CAATCTCCCT ACACGAGCGC CCCGCCGCTG TCCCACACCC CCAATGCCGA CTTCCAGCCC
CCATACTTCC CCCCACCCTA CCAGCCTATC TACCCCCAGT CGCAAGATCC TTACTCCCAC
GTCAACGACC CCTACAGCCT GAACCCCCTG CACGCCCAGC CGCAGCCGCA GCACCCAGGC
TGGCCCGGCC AGAGGCAGAG CCAGGAGTCT GGGCTCCTGC ACACGCACCG GGGGCTGCCT
CACCAGCTGT CGGGCCTGGA TCCTCGCAGG GACTACAGGC GGCACGAGGA CCTCCTGCAC
GGCCCACACG CGCTCAGCTC AGGACTCGGA GACCTCTCGA TCCACTCCTT ACCTCACGCC
ATCGAGGAGG TCCCGCATGT AGAAGACCCG GGTATTAACA TCCCAGATCA AACTGTAATT
AAGAAAGGCC CCGTGTCCCT GTCCAAGTCC AACAGCAATG CCGTCTCCGC CATCCCTATT
AACAAGGACA ACCTCTTCGG CGGCGTGGTG AACCCCAACG AAGTCTTCTG TTCAGTTCCG
GGTCGCCTCT CGCTCCTCAG CTCCACCTCG AAGTACAAGG TCACGGTGGC GGAAGTGCAG
CGGCGGCTCT CACCACCCGA GTGTCTCAAC GCGTCGCTGC TGGGCGGAGT GCTCCGGAGG
GCGAAGTCTA AAAATGGAGG AAGATCTTTA AGAGAAAAAC TGGACAAAAT AGGATTAAAT
CTGCCTGCAG GGAGACGTAA AGCTGCCAAC GTTACCCTGC TCACATCACT AGTAGAGGGA
GAAGCTGTCC ACCTAGCCAG GGACTTTGGG TACGTGTGCG AAACCGAATT TCCTGCCAAA
GCAGTAGCTG AATTTCTCAA CCGACAACAT TCCGATCCCA ATGAGCAAGT GACAAGAAAA
AACATGCTCC TGGCTACAAA ACAGATATGC AAAGAGTTCA CCGACCTGCT GGCTCAGGAC
CGATCTCCCC TGGGGAACTC ACGGCCCAAC CCCATCCTGG AGCCCGGCAT CCAGAGCTGC
TTGACCCACT TCAACCTCAT CTCCCACGGC TTCGGCAGCC CCGCGGTGTG TGCCGCGGTC
ACGGCCCTGC AGAACTATCT CACCGAGGCC CTCAAGGCCA TGGACAAAAT GTACCTCAGC
AACAACCCCA ACAGCCACAC GGACAACAAC GCCAAAAGCA GTGACAAAGA GGAGAAGCAC
AGAAAGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu60957
Accession Version XM_011514833.1
Sequence Information ORF Nucleotide Sequence (Length: 1164bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product transcription factor AP-2-alpha isoform X2
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_007592.16) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
ATGCGTCGGC AGGTAGCAAC CCAGCTCTTT ATGACCAGGA CCGTCACGAC GGCACCAGCA 
ACGGGACGGC ACGGTTGCCC CAGCTGGGCA CTCCTGAACC CCCTGCACGC CCAGCCGCAG
CCGCAGCACC CAGGCTGGCC CGGCCAGAGG CAGAGCCAGG AGTCTGGGCT CCTGCACACG
CACCGGGGGC TGCCTCACCA GCTGTCGGGC CTGGATCCTC GCAGGGACTA CAGGCGGCAC
GAGGACCTCC TGCACGGCCC ACACGCGCTC AGCTCAGGAC TCGGAGACCT CTCGATCCAC
TCCTTACCTC ACGCCATCGA GGAGGTCCCG CATGTAGAAG ACCCGGGTAT TAACATCCCA
GATCAAACTG TAATTAAGAA AGGCCCCGTG TCCCTGTCCA AGTCCAACAG CAATGCCGTC
TCCGCCATCC CTATTAACAA GGACAACCTC TTCGGCGGCG TGGTGAACCC CAACGAAGTC
TTCTGTTCAG TTCCGGGTCG CCTCTCGCTC CTCAGCTCCA CCTCGAAGTA CAAGGTCACG
GTGGCGGAAG TGCAGCGGCG GCTCTCACCA CCCGAGTGTC TCAACGCGTC GCTGCTGGGC
GGAGTGCTCC GGAGGGCGAA GTCTAAAAAT GGAGGAAGAT CTTTAAGAGA AAAACTGGAC
AAAATAGGAT TAAATCTGCC TGCAGGGAGA CGTAAAGCTG CCAACGTTAC CCTGCTCACA
TCACTAGTAG AGGGAGAAGC TGTCCACCTA GCCAGGGACT TTGGGTACGT GTGCGAAACC
GAATTTCCTG CCAAAGCAGT AGCTGAATTT CTCAACCGAC AACATTCCGA TCCCAATGAG
CAAGTGACAA GAAAAAACAT GCTCCTGGCT ACAAAACAGA TATGCAAAGA GTTCACCGAC
CTGCTGGCTC AGGACCGATC TCCCCTGGGG AACTCACGGC CCAACCCCAT CCTGGAGCCC
GGCATCCAGA GCTGCTTGAC CCACTTCAAC CTCATCTCCC ACGGCTTCGG CAGCCCCGCG
GTGTGTGCCG CGGTCACGGC CCTGCAGAAC TATCTCACCG AGGCCCTCAA GGCCATGGAC
AAAATGTACC TCAGCAACAA CCCCAACAGC CACACGGACA ACAACGCCAA AAGCAGTGAC
AAAGAGGAGA AGCACAGAAA GTGA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqXP_011513135.1
CDS16..1179
Misc Feature(1)490..1107(+)
Translation
Position Chain Variation Link
34 34 a, g dbSNP:532547488
39 39 a, g dbSNP:143945720
67 67 a, g, t dbSNP:143258135
89 89 a, g dbSNP:768948369
105 105 a, g dbSNP:9368354
116 116 c, t dbSNP:200131527
117 117 c, t dbSNP:774713482
118 118 c, g dbSNP:376101872
123 123 a, c, t dbSNP:545067807
132 132 a, g dbSNP:773687604
138 138 a, g dbSNP:770326832
154 154 c, t dbSNP:746489683
155 155 c, t dbSNP:779455245
156 156 c, g dbSNP:758008816
162 162 c, g dbSNP:372468982
164 164 c, g dbSNP:778774564
171 171 c, g dbSNP:757104358
181 181 c, g dbSNP:753730365
187 187 c, t dbSNP:764088571
188 188 a, t dbSNP:756034130
201 201 a, g dbSNP:138225261
202 202 a, g dbSNP:767502053
205 205 c, t dbSNP:563009991
219 219 a, g dbSNP:544933565
222 222 a, g dbSNP:766641930
236 236 g, t dbSNP:763273543
237 237 a, c dbSNP:145673154
243 243 c, g dbSNP:200574824
244 244 c, t dbSNP:748618587
245 245 a, g dbSNP:774997299
255 255 a, c dbSNP:771478009
270 270 c, t dbSNP:745441531
279 279 a, c dbSNP:778686750
281 281 a, c dbSNP:770743434
284 284 c, t dbSNP:111353850
285 285 c, t dbSNP:369051842
294 294 a, g dbSNP:777729482
300 300 a, c dbSNP:756019412
309 309 g, t dbSNP:747353442
315 315 c, t dbSNP:752575373
317 317 c, g dbSNP:555997980
326 326 a, t dbSNP:754995203
327 327 c, t dbSNP:375321728
331 331 a, g dbSNP:751678511
339 339 a, g dbSNP:766548263
348 348 c, t dbSNP:758551492
349 349 a, g dbSNP:540208578
356 356 a, g dbSNP:111681798
359 359 a, c dbSNP:765549775
360 360 a, g dbSNP:762057151
362 362 a, g dbSNP:754264393
366 366 g, t dbSNP:528101301
393 393 a, g dbSNP:559183946
402 402 c, g dbSNP:531975577
410 410 c, t dbSNP:764532449
413 413 a, c dbSNP:146735451
417 417 -, gtccaa dbSNP:771955798
421 421 a, g dbSNP:201296512
428 428 a, g dbSNP:565071190
438 438 c, t dbSNP:143363077
442 442 a, g dbSNP:772810778
445 445 c, t dbSNP:764751482
450 450 g, t dbSNP:761543465
456 456 a, g dbSNP:372587710
460 460 a, g dbSNP:768437372
465 465 c, t dbSNP:746862188
468 468 a, c, t dbSNP:772033707
471 471 a, c dbSNP:745892262
473 473 a, g dbSNP:763437712
488 488 a, g dbSNP:202002859
493 493 c, g dbSNP:749528750
495 495 c, g dbSNP:777922831
516 516 c, t dbSNP:756526526
519 519 c, t dbSNP:369302647
538 538 c, t dbSNP:768098328
540 540 a, g dbSNP:755569103
550 550 a, g dbSNP:749849069
552 552 c, g dbSNP:764811179
573 573 a, g dbSNP:761298686
574 574 c, g dbSNP:151344524
575 575 a, c, g dbSNP:151344525
576 576 a, g dbSNP:554807432
582 582 a, c dbSNP:763782805
588 588 a, c, g dbSNP:140905560
589 589 a, g dbSNP:151344526
591 591 a, g dbSNP:151009833
617 617 a, g dbSNP:151344527
624 624 c, g, t dbSNP:142511319
625 625 c, g, t dbSNP:151344528
626 626 c, g dbSNP:151344530
628 628 a, c, g dbSNP:121909574
632 632 c, t dbSNP:151344531
650 650 a, g dbSNP:121909575
656 656 c, t dbSNP:781630462
658 658 c, t dbSNP:769053661
664 664 c, g dbSNP:747379877
670 670 c, g dbSNP:758652364
685 685 c, t dbSNP:35008125
691 691 c, t dbSNP:758856518
717 717 c, t dbSNP:753291798
720 720 c, t dbSNP:777278396
721 721 a, g dbSNP:755697313
730 730 c, t dbSNP:750843820
751 751 a, g dbSNP:267607108
756 756 c, t dbSNP:771879686
768 768 a, c dbSNP:745607212
777 777 c, t dbSNP:369463773
780 780 a, g dbSNP:778860533
783 783 c, t dbSNP:141711078
784 784 a, g dbSNP:377114324
789 789 c, t dbSNP:771617050
790 790 a, g dbSNP:756122879
794 794 c, t dbSNP:752860081
797 797 a, c dbSNP:144275164
813 813 a, c dbSNP:767678528
828 828 c, t dbSNP:1803117
830 830 a, g dbSNP:759768857
836 836 a, g dbSNP:751854479
837 837 a, g dbSNP:766726105
840 840 g, t dbSNP:763437006
844 844 a, g dbSNP:575186761
852 852 c, t dbSNP:770375179
880 880 c, t dbSNP:760066655
891 891 a, g dbSNP:758672228
892 892 c, g dbSNP:750693033
897 897 a, g dbSNP:765634102
908 908 a, t dbSNP:757626207
909 909 c, t dbSNP:754379873
912 912 c, t dbSNP:140377026
922 922 a, g dbSNP:759083592
930 930 c, t dbSNP:774029144
931 931 c, g dbSNP:9350373
932 932 g, t dbSNP:765898042
933 933 a, g dbSNP:762671343
937 937 c, t dbSNP:772807658
939 939 c, t dbSNP:375372321
947 947 a, g dbSNP:747986718
959 959 a, g dbSNP:776521790
975 975 c, t dbSNP:372082918
989 989 a, g dbSNP:768613709
995 995 c, t dbSNP:747045958
1005 1005 c, t dbSNP:780192295
1008 1008 c, t dbSNP:372299435
1011 1011 c, t dbSNP:550611281
1023 1023 c, t dbSNP:779059756
1035 1035 a, g dbSNP:757618280
1040 1040 a, g dbSNP:754293607
1042 1042 g, t dbSNP:778384375
1044 1044 c, g, t dbSNP:181105841
1047 1047 g, t dbSNP:765909703
1050 1050 c, g dbSNP:762430867
1051 1051 a, t dbSNP:750068981
1053 1053 c, g, t dbSNP:2230116
1071 1071 c, g dbSNP:200847258
1074 1074 c, t dbSNP:201494266
1113 1113 -, ctcagcaac dbSNP:760836149
1121 1121 a, c dbSNP:201591227
1122 1122 c, t dbSNP:3734391
1124 1124 a, g dbSNP:772175937
1128 1128 c, t dbSNP:745981703
1132 1132 a, c, g dbSNP:771307700
1140 1140 a, c dbSNP:749620758
1142 1142 c, t dbSNP:1803116
1148 1148 a, g dbSNP:778294642
1150 1150 a, g dbSNP:756614321
1161 1161 a, g dbSNP:374310228
1162 1162 -, gag dbSNP:773291481
1162 1162 a, g dbSNP:781601001
1181 1181 a, g dbSNP:757896248
1183 1183 c, t dbSNP:749936793
1184 1184 c, g dbSNP:764897160
1185 1185 c, t dbSNP:761472794
1186 1186 c, t dbSNP:753566744
1188 1188 c, t dbSNP:763868660
1189 1189 c, g dbSNP:760518852
1191 1191 -, c dbSNP:767561818
1191 1191 c, t dbSNP:775472363
1198 1198 c, t dbSNP:771942212
1203 1203 c, t dbSNP:371339437
1205 1205 a, c dbSNP:552520811
1208 1208 a, g dbSNP:771219549
1215 1215 -, cc dbSNP:761920926
1218 1218 c, t dbSNP:749517602
1219 1219 c, t dbSNP:778198576
1220 1220 a, c dbSNP:770263013
1222 1222 c, t dbSNP:748502364
1223 1223 a, c dbSNP:781698007
1223 1223 -, c dbSNP:774267757
1228 1228 a, g dbSNP:755465363
1232 1232 a, c dbSNP:530677405
1237 1237 c, t dbSNP:563344990
1245 1245 g, t dbSNP:542047656
1260 1260 c, t dbSNP:369680359
1263 1263 a, c dbSNP:574832806
1267 1267 a, c dbSNP:10456013
1271 1271 c, t dbSNP:541008118
1305 1305 c, t dbSNP:764664664
1306 1306 c, g dbSNP:188674648
1307 1307 a, g dbSNP:759057111
1317 1317 a, c dbSNP:558781203
1318 1318 c, t dbSNP:1461010
1329 1329 a, c dbSNP:576370374
1345 1345 g, t dbSNP:554863655
1422 1422 c, t dbSNP:536878759
1476 1476 a, g dbSNP:118042860
1502 1502 -, t dbSNP:34512481
1511 1511 -, t dbSNP:111823522
1512 1512 -, t dbSNP:546903889
1516 1516 a, c dbSNP:2763172
1521 1521 a, c dbSNP:201528167
1522 1522 a, t dbSNP:546690434
1538 1538 -, caa dbSNP:397885453
1549 1549 -, caa dbSNP:776813404
1550 1550 -, caa dbSNP:34426547
1564 1564 c, t dbSNP:9350372
1580 1580 a, g dbSNP:534571057
1592 1592 -, aaaaa dbSNP:560622395
1597 1597 a, t dbSNP:762265236
1611 1611 c, t dbSNP:570465051
1622 1622 c, t dbSNP:552459189
1638 1638 a, g dbSNP:151315569
1677 1677 -, aaaaa dbSNP:544361557
1692 1692 a, g dbSNP:146797011
1713 1713 a, c dbSNP:1045385
1749 1749 a, c dbSNP:548057203
1772 1772 a, g dbSNP:770745416
1775 1775 g, t dbSNP:749647128
1792 1792 a, c dbSNP:184322632
1796 1796 g, t dbSNP:529930646
1805 1805 -, g dbSNP:540540292
1811 1811 -, t dbSNP:773862113
1813 1813 a, t dbSNP:559552401
1829 1829 a, g dbSNP:201450721
1841 1841 a, g dbSNP:541132655
1854 1854 c, g dbSNP:576308493
1857 1857 a, g dbSNP:75419063
1880 1880 a, t dbSNP:564928565
1891 1891 a, g dbSNP:543460673
1907 1907 a, g dbSNP:181681871
1918 1918 g, t dbSNP:147713410
1923 1923 c, t dbSNP:201819112
1924 1924 -, t dbSNP:397965898
1925 1925 c, t dbSNP:74636495
1933 1933 c, t dbSNP:542820219
1934 1934 -, t dbSNP:61569279
1935 1935 -, t dbSNP:546035279
1935 1935 a, t dbSNP:78186274
1953 1953 c, t dbSNP:572623022
1979 1979 a, c dbSNP:574855862
2030 2030 g, t dbSNP:3088288
2034 2034 g, t dbSNP:2763171
2039 2039 a, g dbSNP:770287660
2046 2046 -, t dbSNP:768958142
2059 2059 g, t dbSNP:115631304
2104 2104 a, g dbSNP:2763170
2123 2123 a, g dbSNP:113256477
2134 2134 a, g dbSNP:185414193
2173 2173 c, t dbSNP:558581973
2181 2181 a, c dbSNP:537069740
2187 2187 a, g dbSNP:773868091
2192 2192 a, g dbSNP:781574382
2198 2198 c, g dbSNP:569833793
2261 2261 a, c dbSNP:755049370
2267 2267 g, t dbSNP:2857059
2269 2269 a, t dbSNP:2857060
2288 2288 c, t dbSNP:11553434
2298 2298 c, t dbSNP:747101844
2307 2307 a, c dbSNP:545023610
2338 2338 a, g dbSNP:80094467
2347 2347 a, g dbSNP:780237615
2352 2352 -, ct dbSNP:554956373
2353 2353 c, t dbSNP:193259940
2368 2368 -, tc dbSNP:150236619
2406 2406 a, g dbSNP:2763169
2409 2409 c, t dbSNP:758681260
2480 2480 c, t dbSNP:753621983
2484 2484 -, agt dbSNP:769945457
2493 2493 g, t dbSNP:186469860
2526 2526 a, g dbSNP:573067252
2558 2558 -, t dbSNP:398094002
2566 2566 -, t dbSNP:79168174
2590 2590 c, g dbSNP:763807060
2675 2675 a, g dbSNP:745977233
2702 2702 a, c dbSNP:2763168
2722 2722 g, t dbSNP:752628820
2767 2767 a, g dbSNP:552923535
2803 2803 a, g dbSNP:16893358
2829 2829 -, ttgt dbSNP:372257234

Target ORF information:

RefSeq Version XM_011514833
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) (TFAP2A), transcript variant X2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011514833

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
ATGCGTCGGC AGGTAGCAAC CCAGCTCTTT ATGACCAGGA CCGTCACGAC GGCACCAGCA 
ACGGGACGGC ACGGTTGCCC CAGCTGGGCA CTCCTGAACC CCCTGCACGC CCAGCCGCAG
CCGCAGCACC CAGGCTGGCC CGGCCAGAGG CAGAGCCAGG AGTCTGGGCT CCTGCACACG
CACCGGGGGC TGCCTCACCA GCTGTCGGGC CTGGATCCTC GCAGGGACTA CAGGCGGCAC
GAGGACCTCC TGCACGGCCC ACACGCGCTC AGCTCAGGAC TCGGAGACCT CTCGATCCAC
TCCTTACCTC ACGCCATCGA GGAGGTCCCG CATGTAGAAG ACCCGGGTAT TAACATCCCA
GATCAAACTG TAATTAAGAA AGGCCCCGTG TCCCTGTCCA AGTCCAACAG CAATGCCGTC
TCCGCCATCC CTATTAACAA GGACAACCTC TTCGGCGGCG TGGTGAACCC CAACGAAGTC
TTCTGTTCAG TTCCGGGTCG CCTCTCGCTC CTCAGCTCCA CCTCGAAGTA CAAGGTCACG
GTGGCGGAAG TGCAGCGGCG GCTCTCACCA CCCGAGTGTC TCAACGCGTC GCTGCTGGGC
GGAGTGCTCC GGAGGGCGAA GTCTAAAAAT GGAGGAAGAT CTTTAAGAGA AAAACTGGAC
AAAATAGGAT TAAATCTGCC TGCAGGGAGA CGTAAAGCTG CCAACGTTAC CCTGCTCACA
TCACTAGTAG AGGGAGAAGC TGTCCACCTA GCCAGGGACT TTGGGTACGT GTGCGAAACC
GAATTTCCTG CCAAAGCAGT AGCTGAATTT CTCAACCGAC AACATTCCGA TCCCAATGAG
CAAGTGACAA GAAAAAACAT GCTCCTGGCT ACAAAACAGA TATGCAAAGA GTTCACCGAC
CTGCTGGCTC AGGACCGATC TCCCCTGGGG AACTCACGGC CCAACCCCAT CCTGGAGCCC
GGCATCCAGA GCTGCTTGAC CCACTTCAAC CTCATCTCCC ACGGCTTCGG CAGCCCCGCG
GTGTGTGCCG CGGTCACGGC CCTGCAGAAC TATCTCACCG AGGCCCTCAA GGCCATGGAC
AAAATGTACC TCAGCAACAA CCCCAACAGC CACACGGACA ACAACGCCAA AAGCAGTGAC
AAAGAGGAGA AGCACAGAAA GTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu16263
Accession Version NM_003220.2
Sequence Information ORF Nucleotide Sequence (Length: 1314bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product transcription factor AP-2-alpha isoform a
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL138885.21 and X52611.1. This sequence is a reference standard in the RefSeqGene project. On Jun 21, 2006 this sequence version replaced gi:4507440. Summary: The protein encoded by this gene is a transcription factor that binds the consensus sequence 5'-GCCNNNGGC-3'. The encoded protein functions as either a homodimer or as a heterodimer with similar family members. This protein activates the transcription of some genes while inhibiting the transcription of others. Defects in this gene are a cause of branchiooculofacial syndrome (BOFS). Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Dec 2009]. Transcript Variant: This variant (1) encodes the longest isoform (a). CCDS Note: A downstream start codon is used for this CCDS representation based on sequencing of the purified protein in PMID:3063603, which shows that the second in-frame start codon is used. An upstream start codon exists and would result in a protein that is 2 aa longer at the N-terminus, but there is currently no evidence for this longer protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##RefSeq-Attributes-START## CDS uses downstream in-frame AUG :: experimental evidence (PMID:3063603) ##RefSeq-Attributes-END## ##Evidence-Data-START## Transcript exon combination :: M36711.1, X52611.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2147596 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
ATGCTTTGGA AATTGACGGA TAATATCAAG TACGAGGACT GCGAGGACCG TCACGACGGC 
ACCAGCAACG GGACGGCACG GTTGCCCCAG CTGGGCACTG TAGGTCAATC TCCCTACACG
AGCGCCCCGC CGCTGTCCCA CACCCCCAAT GCCGACTTCC AGCCCCCATA CTTCCCCCCA
CCCTACCAGC CTATCTACCC CCAGTCGCAA GATCCTTACT CCCACGTCAA CGACCCCTAC
AGCCTGAACC CCCTGCACGC CCAGCCGCAG CCGCAGCACC CAGGCTGGCC CGGCCAGAGG
CAGAGCCAGG AGTCTGGGCT CCTGCACACG CACCGGGGGC TGCCTCACCA GCTGTCGGGC
CTGGATCCTC GCAGGGACTA CAGGCGGCAC GAGGACCTCC TGCACGGCCC ACACGCGCTC
AGCTCAGGAC TCGGAGACCT CTCGATCCAC TCCTTACCTC ACGCCATCGA GGAGGTCCCG
CATGTAGAAG ACCCGGGTAT TAACATCCCA GATCAAACTG TAATTAAGAA AGGCCCCGTG
TCCCTGTCCA AGTCCAACAG CAATGCCGTC TCCGCCATCC CTATTAACAA GGACAACCTC
TTCGGCGGCG TGGTGAACCC CAACGAAGTC TTCTGTTCAG TTCCGGGTCG CCTCTCGCTC
CTCAGCTCCA CCTCGAAGTA CAAGGTCACG GTGGCGGAAG TGCAGCGGCG GCTCTCACCA
CCCGAGTGTC TCAACGCGTC GCTGCTGGGC GGAGTGCTCC GGAGGGCGAA GTCTAAAAAT
GGAGGAAGAT CTTTAAGAGA AAAACTGGAC AAAATAGGAT TAAATCTGCC TGCAGGGAGA
CGTAAAGCTG CCAACGTTAC CCTGCTCACA TCACTAGTAG AGGGAGAAGC TGTCCACCTA
GCCAGGGACT TTGGGTACGT GTGCGAAACC GAATTTCCTG CCAAAGCAGT AGCTGAATTT
CTCAACCGAC AACATTCCGA TCCCAATGAG CAAGTGACAA GAAAAAACAT GCTCCTGGCT
ACAAAACAGA TATGCAAAGA GTTCACCGAC CTGCTGGCTC AGGACCGATC TCCCCTGGGG
AACTCACGGC CCAACCCCAT CCTGGAGCCC GGCATCCAGA GCTGCTTGAC CCACTTCAAC
CTCATCTCCC ACGGCTTCGG CAGCCCCGCG GTGTGTGCCG CGGTCACGGC CCTGCAGAAC
TATCTCACCG AGGCCCTCAA GGCCATGGAC AAAATGTACC TCAGCAACAA CCCCAACAGC
CACACGGACA ACAACGCCAA AAGCAGTGAC AAAGAGGAGA AGCACAGAAA GTGA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_003211.1
CDS253..1566
Misc Feature(1)307..309(+)
Misc Feature(2)307..309(+)
Misc Feature(3)307..309(+)
Misc Feature(4)421..438(+)
Misc Feature(5)877..1494(+)
Misc Feature(6)967..969(+)
Misc Feature(7)1090..1482(+)
Exon (1)1..297
Gene:TFAP2A
Gene Synonym:
Exon (2)298..732
Gene:TFAP2A
Gene Synonym:
Exon (3)733..784
Gene:TFAP2A
Gene Synonym:
Exon (4)785..1016
Gene:TFAP2A
Gene Synonym:
Exon (5)1017..1135
Gene:TFAP2A
Gene Synonym:
Exon (6)1136..1277
Gene:TFAP2A
Gene Synonym:
Exon (7)1278..3300
Gene:TFAP2A
Gene Synonym:
Translation
Position Chain Variation Link
24 24 a, c dbSNP:528537255
27 27 -, ctcctcgccctt dbSNP:370163373
63 63 c, g, t dbSNP:564609127
64 64 c, t dbSNP:546508077
90 90 a, g dbSNP:530986425
97 97 a, t dbSNP:563924766
110 110 c, t dbSNP:34658766
146 146 c, t dbSNP:573396734
153 153 a, c dbSNP:555081767
161 161 a, g dbSNP:771512288
164 164 c, g dbSNP:1800927
165 165 a, g dbSNP:572531421
176 176 g, t dbSNP:374812295
204 204 g, t dbSNP:754007046
206 206 c, g dbSNP:764440862
207 207 a, g dbSNP:760931984
211 211 a, c dbSNP:1139846
212 212 a, g dbSNP:753148250
216 216 c, g dbSNP:768100385
217 217 a, c dbSNP:760145973
225 225 a, g dbSNP:373787155
227 227 a, t dbSNP:554417616
229 229 a, g dbSNP:761453420
233 233 a, c, g dbSNP:76066093
238 238 c, t dbSNP:746748404
242 242 g, t dbSNP:779853155
276 276 c, t dbSNP:377304443
284 284 a, g dbSNP:745818259
285 285 c, t dbSNP:778893701
290 290 a, g dbSNP:757277133
311 311 a, g, t dbSNP:143258135
333 333 a, g dbSNP:768948369
349 349 a, g dbSNP:9368354
353 353 g, t dbSNP:780216169
356 356 g, t dbSNP:772479857
357 357 g, t dbSNP:746272068
362 362 c, t dbSNP:779448987
363 363 a, t dbSNP:757798850
372 372 g, t dbSNP:752157129
376 376 g, t dbSNP:373246714
385 385 c, t dbSNP:754562525
386 386 c, t dbSNP:751224702
387 387 a, g dbSNP:149126243
392 392 a, c dbSNP:762787739
394 394 a, c dbSNP:750226796
395 395 c, g dbSNP:765183722
398 398 c, t dbSNP:761863117
399 399 -, cc dbSNP:753073720
400 400 a, c dbSNP:776792762
401 401 a, g dbSNP:527785340
403 403 c, g dbSNP:760904143
407 407 a, c dbSNP:775764363
409 409 c, t dbSNP:772228476
412 412 -, a dbSNP:34436436
417 417 c, t dbSNP:746209784
420 420 a, c dbSNP:779173083
423 423 c, t dbSNP:771371649
425 425 c, t dbSNP:749803917
431 431 a, c dbSNP:778321721
432 432 a, c dbSNP:754476051
437 437 a, c dbSNP:746550070
441 441 a, g dbSNP:779727040
449 449 a, g dbSNP:758018662
454 454 c, g dbSNP:750185451
459 459 a, g dbSNP:765135263
465 465 a, t dbSNP:560684169
466 466 a, c dbSNP:753822419
472 472 a, t dbSNP:764184708
474 474 c, g dbSNP:760782033
483 483 c, g dbSNP:775468691
492 492 c, t dbSNP:767736500
503 503 c, t dbSNP:200131527
504 504 c, t dbSNP:774713482
505 505 c, g dbSNP:376101872
510 510 a, c, t dbSNP:545067807
519 519 a, g dbSNP:773687604
525 525 a, g dbSNP:770326832
541 541 c, t dbSNP:746489683
542 542 c, t dbSNP:779455245
543 543 c, g dbSNP:758008816
549 549 c, g dbSNP:372468982
551 551 c, g dbSNP:778774564
558 558 c, g dbSNP:757104358
568 568 c, g dbSNP:753730365
574 574 c, t dbSNP:764088571
575 575 a, t dbSNP:756034130
588 588 a, g dbSNP:138225261
589 589 a, g dbSNP:767502053
592 592 c, t dbSNP:563009991
606 606 a, g dbSNP:544933565
609 609 a, g dbSNP:766641930
623 623 g, t dbSNP:763273543
624 624 a, c dbSNP:145673154
630 630 c, g dbSNP:200574824
631 631 c, t dbSNP:748618587
632 632 a, g dbSNP:774997299
642 642 a, c dbSNP:771478009
657 657 c, t dbSNP:745441531
666 666 a, c dbSNP:778686750
668 668 a, c dbSNP:770743434
671 671 c, t dbSNP:111353850
672 672 c, t dbSNP:369051842
681 681 a, g dbSNP:777729482
687 687 a, c dbSNP:756019412
696 696 g, t dbSNP:747353442
702 702 c, t dbSNP:752575373
704 704 c, g dbSNP:555997980
713 713 a, t dbSNP:754995203
714 714 c, t dbSNP:375321728
718 718 a, g dbSNP:751678511
726 726 a, g dbSNP:766548263
735 735 c, t dbSNP:758551492
736 736 a, g dbSNP:540208578
743 743 a, g dbSNP:111681798
746 746 a, c dbSNP:765549775
747 747 a, g dbSNP:762057151
749 749 a, g dbSNP:754264393
753 753 g, t dbSNP:528101301
780 780 a, g dbSNP:559183946
789 789 c, g dbSNP:531975577
797 797 c, t dbSNP:764532449
800 800 a, c dbSNP:146735451
804 804 -, gtccaa dbSNP:771955798
808 808 a, g dbSNP:201296512
815 815 a, g dbSNP:565071190
825 825 c, t dbSNP:143363077
829 829 a, g dbSNP:772810778
832 832 c, t dbSNP:764751482
837 837 g, t dbSNP:761543465
843 843 a, g dbSNP:372587710
847 847 a, g dbSNP:768437372
852 852 c, t dbSNP:746862188
855 855 a, c, t dbSNP:772033707
858 858 a, c dbSNP:745892262
860 860 a, g dbSNP:763437712
875 875 a, g dbSNP:202002859
880 880 c, g dbSNP:749528750
882 882 c, g dbSNP:777922831
903 903 c, t dbSNP:756526526
906 906 c, t dbSNP:369302647
925 925 c, t dbSNP:768098328
927 927 a, g dbSNP:755569103
937 937 a, g dbSNP:749849069
939 939 c, g dbSNP:764811179
960 960 a, g dbSNP:761298686
961 961 c, g dbSNP:151344524
962 962 a, c, g dbSNP:151344525
963 963 a, g dbSNP:554807432
969 969 a, c dbSNP:763782805
975 975 a, c, g dbSNP:140905560
976 976 a, g dbSNP:151344526
978 978 a, g dbSNP:151009833
1004 1004 a, g dbSNP:151344527
1011 1011 c, g, t dbSNP:142511319
1012 1012 c, g, t dbSNP:151344528
1013 1013 c, g dbSNP:151344530
1015 1015 a, c, g dbSNP:121909574
1019 1019 c, t dbSNP:151344531
1037 1037 a, g dbSNP:121909575
1043 1043 c, t dbSNP:781630462
1045 1045 c, t dbSNP:769053661
1051 1051 c, g dbSNP:747379877
1057 1057 c, g dbSNP:758652364
1072 1072 c, t dbSNP:35008125
1078 1078 c, t dbSNP:758856518
1104 1104 c, t dbSNP:753291798
1107 1107 c, t dbSNP:777278396
1108 1108 a, g dbSNP:755697313
1117 1117 c, t dbSNP:750843820
1138 1138 a, g dbSNP:267607108
1143 1143 c, t dbSNP:771879686
1155 1155 a, c dbSNP:745607212
1164 1164 c, t dbSNP:369463773
1167 1167 a, g dbSNP:778860533
1170 1170 c, t dbSNP:141711078
1171 1171 a, g dbSNP:377114324
1176 1176 c, t dbSNP:771617050
1177 1177 a, g dbSNP:756122879
1181 1181 c, t dbSNP:752860081
1184 1184 a, c dbSNP:144275164
1200 1200 a, c dbSNP:767678528
1215 1215 c, t dbSNP:1803117
1217 1217 a, g dbSNP:759768857
1223 1223 a, g dbSNP:751854479
1224 1224 a, g dbSNP:766726105
1227 1227 g, t dbSNP:763437006
1231 1231 a, g dbSNP:575186761
1239 1239 c, t dbSNP:770375179
1267 1267 c, t dbSNP:760066655
1278 1278 a, g dbSNP:758672228
1279 1279 c, g dbSNP:750693033
1284 1284 a, g dbSNP:765634102
1295 1295 a, t dbSNP:757626207
1296 1296 c, t dbSNP:754379873
1299 1299 c, t dbSNP:140377026
1309 1309 a, g dbSNP:759083592
1317 1317 c, t dbSNP:774029144
1318 1318 c, g dbSNP:9350373
1319 1319 g, t dbSNP:765898042
1320 1320 a, g dbSNP:762671343
1324 1324 c, t dbSNP:772807658
1326 1326 c, t dbSNP:375372321
1334 1334 a, g dbSNP:747986718
1346 1346 a, g dbSNP:776521790
1362 1362 c, t dbSNP:372082918
1376 1376 a, g dbSNP:768613709
1382 1382 c, t dbSNP:747045958
1392 1392 c, t dbSNP:780192295
1395 1395 c, t dbSNP:372299435
1398 1398 c, t dbSNP:550611281
1410 1410 c, t dbSNP:779059756
1422 1422 a, g dbSNP:757618280
1427 1427 a, g dbSNP:754293607
1429 1429 g, t dbSNP:778384375
1431 1431 c, g, t dbSNP:181105841
1434 1434 g, t dbSNP:765909703
1437 1437 c, g dbSNP:762430867
1438 1438 a, t dbSNP:750068981
1440 1440 c, g, t dbSNP:2230116
1458 1458 c, g dbSNP:200847258
1461 1461 c, t dbSNP:201494266
1500 1500 -, ctcagcaac dbSNP:760836149
1508 1508 a, c dbSNP:201591227
1509 1509 c, t dbSNP:3734391
1511 1511 a, g dbSNP:772175937
1515 1515 c, t dbSNP:745981703
1519 1519 a, c, g dbSNP:771307700
1527 1527 a, c dbSNP:749620758
1529 1529 c, t dbSNP:1803116
1535 1535 a, g dbSNP:778294642
1537 1537 a, g dbSNP:756614321
1548 1548 a, g dbSNP:374310228
1549 1549 -, gag dbSNP:773291481
1549 1549 a, g dbSNP:781601001
1568 1568 a, g dbSNP:757896248
1570 1570 c, t dbSNP:749936793
1571 1571 c, g dbSNP:764897160
1572 1572 c, t dbSNP:761472794
1573 1573 c, t dbSNP:753566744
1575 1575 c, t dbSNP:763868660
1576 1576 c, g dbSNP:760518852
1578 1578 -, c dbSNP:767561818
1578 1578 c, t dbSNP:775472363
1585 1585 c, t dbSNP:771942212
1590 1590 c, t dbSNP:371339437
1592 1592 a, c dbSNP:552520811
1595 1595 a, g dbSNP:771219549
1602 1602 -, cc dbSNP:761920926
1605 1605 c, t dbSNP:749517602
1606 1606 c, t dbSNP:778198576
1607 1607 a, c dbSNP:770263013
1609 1609 c, t dbSNP:748502364
1610 1610 a, c dbSNP:781698007
1610 1610 -, c dbSNP:774267757
1615 1615 a, g dbSNP:755465363
1619 1619 a, c dbSNP:530677405
1624 1624 c, t dbSNP:563344990
1632 1632 g, t dbSNP:542047656
1647 1647 c, t dbSNP:369680359
1650 1650 a, c dbSNP:574832806
1654 1654 a, c dbSNP:10456013
1658 1658 c, t dbSNP:541008118
1692 1692 c, t dbSNP:764664664
1693 1693 c, g dbSNP:188674648
1694 1694 a, g dbSNP:759057111
1704 1704 a, c dbSNP:558781203
1705 1705 c, t dbSNP:1461010
1716 1716 a, c dbSNP:576370374
1732 1732 g, t dbSNP:554863655
1809 1809 c, t dbSNP:536878759
1863 1863 a, g dbSNP:118042860
1889 1889 -, t dbSNP:34512481
1898 1898 -, t dbSNP:111823522
1899 1899 -, t dbSNP:546903889
1903 1903 a, c dbSNP:2763172
1908 1908 a, c dbSNP:201528167
1909 1909 a, t dbSNP:546690434
1925 1925 -, caa dbSNP:397885453
1936 1936 -, caa dbSNP:776813404
1937 1937 -, caa dbSNP:34426547
1951 1951 c, t dbSNP:9350372
1967 1967 a, g dbSNP:534571057
1979 1979 -, aaaaa dbSNP:560622395
1984 1984 a, t dbSNP:762265236
1998 1998 c, t dbSNP:570465051
2009 2009 c, t dbSNP:552459189
2025 2025 a, g dbSNP:151315569
2064 2064 -, aaaaa dbSNP:544361557
2079 2079 a, g dbSNP:146797011
2100 2100 a, c dbSNP:1045385
2136 2136 a, c dbSNP:548057203
2159 2159 a, g dbSNP:770745416
2162 2162 g, t dbSNP:749647128
2179 2179 a, c dbSNP:184322632
2183 2183 g, t dbSNP:529930646
2192 2192 -, g dbSNP:540540292
2198 2198 -, t dbSNP:773862113
2200 2200 a, t dbSNP:559552401
2216 2216 a, g dbSNP:201450721
2228 2228 a, g dbSNP:541132655
2241 2241 c, g dbSNP:576308493
2244 2244 a, g dbSNP:75419063
2267 2267 a, t dbSNP:564928565
2278 2278 a, g dbSNP:543460673
2294 2294 a, g dbSNP:181681871
2305 2305 g, t dbSNP:147713410
2310 2310 c, t dbSNP:201819112
2311 2311 -, t dbSNP:397965898
2312 2312 c, t dbSNP:74636495
2320 2320 c, t dbSNP:542820219
2321 2321 -, t dbSNP:61569279
2322 2322 -, t dbSNP:546035279
2322 2322 a, t dbSNP:78186274
2340 2340 c, t dbSNP:572623022
2366 2366 a, c dbSNP:574855862
2417 2417 g, t dbSNP:3088288
2421 2421 g, t dbSNP:2763171
2426 2426 a, g dbSNP:770287660
2433 2433 -, t dbSNP:768958142
2446 2446 g, t dbSNP:115631304
2491 2491 a, g dbSNP:2763170
2510 2510 a, g dbSNP:113256477
2521 2521 a, g dbSNP:185414193
2560 2560 c, t dbSNP:558581973
2568 2568 a, c dbSNP:537069740
2574 2574 a, g dbSNP:773868091
2579 2579 a, g dbSNP:781574382
2585 2585 c, g dbSNP:569833793
2648 2648 a, c dbSNP:755049370
2654 2654 g, t dbSNP:2857059
2656 2656 a, t dbSNP:2857060
2675 2675 c, t dbSNP:11553434
2685 2685 c, t dbSNP:747101844
2694 2694 a, c dbSNP:545023610
2725 2725 a, g dbSNP:80094467
2734 2734 a, g dbSNP:780237615
2739 2739 -, ct dbSNP:554956373
2740 2740 c, t dbSNP:193259940
2755 2755 -, tc dbSNP:150236619
2793 2793 a, g dbSNP:2763169
2796 2796 c, t dbSNP:758681260
2867 2867 c, t dbSNP:753621983
2871 2871 -, agt dbSNP:769945457
2880 2880 g, t dbSNP:186469860
2913 2913 a, g dbSNP:573067252
2945 2945 -, t dbSNP:398094002
2953 2953 -, t dbSNP:79168174
2977 2977 c, g dbSNP:763807060
3062 3062 a, g dbSNP:745977233
3089 3089 a, c dbSNP:2763168
3109 3109 g, t dbSNP:752628820
3154 3154 a, g dbSNP:552923535
3190 3190 a, g dbSNP:16893358
3216 3216 -, ttgt dbSNP:372257234

Target ORF information:

RefSeq Version NM_003220
Organism Homo sapiens (human)
Definition Homo sapiens transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) (TFAP2A), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_003220

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
ATGCTTTGGA AATTGACGGA TAATATCAAG TACGAGGACT GCGAGGACCG TCACGACGGC 
ACCAGCAACG GGACGGCACG GTTGCCCCAG CTGGGCACTG TAGGTCAATC TCCCTACACG
AGCGCCCCGC CGCTGTCCCA CACCCCCAAT GCCGACTTCC AGCCCCCATA CTTCCCCCCA
CCCTACCAGC CTATCTACCC CCAGTCGCAA GATCCTTACT CCCACGTCAA CGACCCCTAC
AGCCTGAACC CCCTGCACGC CCAGCCGCAG CCGCAGCACC CAGGCTGGCC CGGCCAGAGG
CAGAGCCAGG AGTCTGGGCT CCTGCACACG CACCGGGGGC TGCCTCACCA GCTGTCGGGC
CTGGATCCTC GCAGGGACTA CAGGCGGCAC GAGGACCTCC TGCACGGCCC ACACGCGCTC
AGCTCAGGAC TCGGAGACCT CTCGATCCAC TCCTTACCTC ACGCCATCGA GGAGGTCCCG
CATGTAGAAG ACCCGGGTAT TAACATCCCA GATCAAACTG TAATTAAGAA AGGCCCCGTG
TCCCTGTCCA AGTCCAACAG CAATGCCGTC TCCGCCATCC CTATTAACAA GGACAACCTC
TTCGGCGGCG TGGTGAACCC CAACGAAGTC TTCTGTTCAG TTCCGGGTCG CCTCTCGCTC
CTCAGCTCCA CCTCGAAGTA CAAGGTCACG GTGGCGGAAG TGCAGCGGCG GCTCTCACCA
CCCGAGTGTC TCAACGCGTC GCTGCTGGGC GGAGTGCTCC GGAGGGCGAA GTCTAAAAAT
GGAGGAAGAT CTTTAAGAGA AAAACTGGAC AAAATAGGAT TAAATCTGCC TGCAGGGAGA
CGTAAAGCTG CCAACGTTAC CCTGCTCACA TCACTAGTAG AGGGAGAAGC TGTCCACCTA
GCCAGGGACT TTGGGTACGT GTGCGAAACC GAATTTCCTG CCAAAGCAGT AGCTGAATTT
CTCAACCGAC AACATTCCGA TCCCAATGAG CAAGTGACAA GAAAAAACAT GCTCCTGGCT
ACAAAACAGA TATGCAAAGA GTTCACCGAC CTGCTGGCTC AGGACCGATC TCCCCTGGGG
AACTCACGGC CCAACCCCAT CCTGGAGCCC GGCATCCAGA GCTGCTTGAC CCACTTCAAC
CTCATCTCCC ACGGCTTCGG CAGCCCCGCG GTGTGTGCCG CGGTCACGGC CCTGCAGAAC
TATCTCACCG AGGCCCTCAA GGCCATGGAC AAAATGTACC TCAGCAACAA CCCCAACAGC
CACACGGACA ACAACGCCAA AAGCAGTGAC AAAGAGGAGA AGCACAGAAA GTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu16217
Accession Version NM_001032280.2
Sequence Information ORF Nucleotide Sequence (Length: 1296bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product transcription factor AP-2-alpha isoform b
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC017754.1, X52611.1 and AL138885.21. On Jun 21, 2006 this sequence version replaced gi:73760406. Summary: The protein encoded by this gene is a transcription factor that binds the consensus sequence 5'-GCCNNNGGC-3'. The encoded protein functions as either a homodimer or as a heterodimer with similar family members. This protein activates the transcription of some genes while inhibiting the transcription of others. Defects in this gene are a cause of branchiooculofacial syndrome (BOFS). Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Dec 2009]. Transcript Variant: This variant (2) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (b) has a shorter and distinct N-terminus compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC017754.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2147596 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
ATGTTAGTTC ACAGTTTTTC AGCCATGGAC CGTCACGACG GCACCAGCAA CGGGACGGCA 
CGGTTGCCCC AGCTGGGCAC TGTAGGTCAA TCTCCCTACA CGAGCGCCCC GCCGCTGTCC
CACACCCCCA ATGCCGACTT CCAGCCCCCA TACTTCCCCC CACCCTACCA GCCTATCTAC
CCCCAGTCGC AAGATCCTTA CTCCCACGTC AACGACCCCT ACAGCCTGAA CCCCCTGCAC
GCCCAGCCGC AGCCGCAGCA CCCAGGCTGG CCCGGCCAGA GGCAGAGCCA GGAGTCTGGG
CTCCTGCACA CGCACCGGGG GCTGCCTCAC CAGCTGTCGG GCCTGGATCC TCGCAGGGAC
TACAGGCGGC ACGAGGACCT CCTGCACGGC CCACACGCGC TCAGCTCAGG ACTCGGAGAC
CTCTCGATCC ACTCCTTACC TCACGCCATC GAGGAGGTCC CGCATGTAGA AGACCCGGGT
ATTAACATCC CAGATCAAAC TGTAATTAAG AAAGGCCCCG TGTCCCTGTC CAAGTCCAAC
AGCAATGCCG TCTCCGCCAT CCCTATTAAC AAGGACAACC TCTTCGGCGG CGTGGTGAAC
CCCAACGAAG TCTTCTGTTC AGTTCCGGGT CGCCTCTCGC TCCTCAGCTC CACCTCGAAG
TACAAGGTCA CGGTGGCGGA AGTGCAGCGG CGGCTCTCAC CACCCGAGTG TCTCAACGCG
TCGCTGCTGG GCGGAGTGCT CCGGAGGGCG AAGTCTAAAA ATGGAGGAAG ATCTTTAAGA
GAAAAACTGG ACAAAATAGG ATTAAATCTG CCTGCAGGGA GACGTAAAGC TGCCAACGTT
ACCCTGCTCA CATCACTAGT AGAGGGAGAA GCTGTCCACC TAGCCAGGGA CTTTGGGTAC
GTGTGCGAAA CCGAATTTCC TGCCAAAGCA GTAGCTGAAT TTCTCAACCG ACAACATTCC
GATCCCAATG AGCAAGTGAC AAGAAAAAAC ATGCTCCTGG CTACAAAACA GATATGCAAA
GAGTTCACCG ACCTGCTGGC TCAGGACCGA TCTCCCCTGG GGAACTCACG GCCCAACCCC
ATCCTGGAGC CCGGCATCCA GAGCTGCTTG ACCCACTTCA ACCTCATCTC CCACGGCTTC
GGCAGCCCCG CGGTGTGTGC CGCGGTCACG GCCCTGCAGA ACTATCTCAC CGAGGCCCTC
AAGGCCATGG ACAAAATGTA CCTCAGCAAC AACCCCAACA GCCACACGGA CAACAACGCC
AAAAGCAGTG ACAAAGAGGA GAAGCACAGA AAGTGA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_001027451.1
CDS779..2074
Misc Feature(1)752..754(+)
Misc Feature(2)815..817(+)
Misc Feature(3)815..817(+)
Misc Feature(4)815..817(+)
Misc Feature(5)1385..2002(+)
Exon (1)1..805
Gene:TFAP2A
Gene Synonym:
Exon (2)806..1240
Gene:TFAP2A
Gene Synonym:
Exon (3)1241..1292
Gene:TFAP2A
Gene Synonym:
Exon (4)1293..1524
Gene:TFAP2A
Gene Synonym:
Exon (5)1525..1643
Gene:TFAP2A
Gene Synonym:
Exon (6)1644..1785
Gene:TFAP2A
Gene Synonym:
Exon (7)1786..3808
Gene:TFAP2A
Gene Synonym:
Translation
Position Chain Variation Link
53 53 a, t dbSNP:772960265
76 76 a, t dbSNP:769611036
80 80 a, t dbSNP:530497820
133 133 c, t dbSNP:563290697
136 136 a, c dbSNP:542107736
141 141 c, g dbSNP:76414670
145 145 c, g dbSNP:547892972
146 146 c, g dbSNP:559734334
151 151 a, g dbSNP:771648656
154 154 c, t dbSNP:541202974
155 155 g, t dbSNP:376944947
168 168 c, g dbSNP:576989721
175 175 c, g dbSNP:538409765
177 177 a, t dbSNP:141438908
196 196 c, g dbSNP:528943997
208 208 c, t dbSNP:767807606
238 238 c, g dbSNP:543565948
241 241 c, t dbSNP:374147114
278 278 c, g dbSNP:554546052
366 366 a, g dbSNP:536291631
397 397 c, t dbSNP:2763141
401 401 a, c dbSNP:556250805
420 420 a, g dbSNP:1675414
446 446 a, c dbSNP:554079745
448 448 a, g dbSNP:539202570
453 453 c, g dbSNP:2763140
461 461 -, cact dbSNP:377356365
464 464 -, tcac dbSNP:567012494
465 465 c, t dbSNP:781730224
537 537 a, g dbSNP:571769353
552 552 c, g dbSNP:552216962
574 574 c, g dbSNP:374038213
581 581 a, g dbSNP:769041892
612 612 c, g dbSNP:2763067
617 617 a, g dbSNP:530532763
622 622 c, g dbSNP:569624673
632 632 a, g dbSNP:780568535
645 645 c, g dbSNP:548207288
669 669 c, g dbSNP:529747420
698 698 c, t dbSNP:747485366
699 699 a, g dbSNP:377709695
706 706 c, t dbSNP:559662546
729 729 a, g dbSNP:748390203
730 730 g, t dbSNP:781630026
738 738 g, t dbSNP:755382032
742 742 c, t dbSNP:752020977
745 745 -, t dbSNP:753506019
746 746 c, t dbSNP:766963491
750 750 c, t dbSNP:758974177
757 757 c, t dbSNP:376803049
763 763 c, g dbSNP:763674137
764 764 a, c dbSNP:760178779
774 774 -, ttc dbSNP:779612972
774 774 c, t dbSNP:371745919
776 776 c, t dbSNP:767212411
791 791 a, g dbSNP:759300800
792 792 -, g dbSNP:755646771
819 819 a, g, t dbSNP:143258135
841 841 a, g dbSNP:768948369
857 857 a, g dbSNP:9368354
861 861 g, t dbSNP:780216169
864 864 g, t dbSNP:772479857
865 865 g, t dbSNP:746272068
870 870 c, t dbSNP:779448987
871 871 a, t dbSNP:757798850
880 880 g, t dbSNP:752157129
884 884 g, t dbSNP:373246714
893 893 c, t dbSNP:754562525
894 894 c, t dbSNP:751224702
895 895 a, g dbSNP:149126243
900 900 a, c dbSNP:762787739
902 902 a, c dbSNP:750226796
903 903 c, g dbSNP:765183722
906 906 c, t dbSNP:761863117
907 907 -, cc dbSNP:753073720
908 908 a, c dbSNP:776792762
909 909 a, g dbSNP:527785340
911 911 c, g dbSNP:760904143
915 915 a, c dbSNP:775764363
917 917 c, t dbSNP:772228476
920 920 -, a dbSNP:34436436
925 925 c, t dbSNP:746209784
928 928 a, c dbSNP:779173083
931 931 c, t dbSNP:771371649
933 933 c, t dbSNP:749803917
939 939 a, c dbSNP:778321721
940 940 a, c dbSNP:754476051
945 945 a, c dbSNP:746550070
949 949 a, g dbSNP:779727040
957 957 a, g dbSNP:758018662
962 962 c, g dbSNP:750185451
967 967 a, g dbSNP:765135263
973 973 a, t dbSNP:560684169
974 974 a, c dbSNP:753822419
980 980 a, t dbSNP:764184708
982 982 c, g dbSNP:760782033
991 991 c, g dbSNP:775468691
1000 1000 c, t dbSNP:767736500
1011 1011 c, t dbSNP:200131527
1012 1012 c, t dbSNP:774713482
1013 1013 c, g dbSNP:376101872
1018 1018 a, c, t dbSNP:545067807
1027 1027 a, g dbSNP:773687604
1033 1033 a, g dbSNP:770326832
1049 1049 c, t dbSNP:746489683
1050 1050 c, t dbSNP:779455245
1051 1051 c, g dbSNP:758008816
1057 1057 c, g dbSNP:372468982
1059 1059 c, g dbSNP:778774564
1066 1066 c, g dbSNP:757104358
1076 1076 c, g dbSNP:753730365
1082 1082 c, t dbSNP:764088571
1083 1083 a, t dbSNP:756034130
1096 1096 a, g dbSNP:138225261
1097 1097 a, g dbSNP:767502053
1100 1100 c, t dbSNP:563009991
1114 1114 a, g dbSNP:544933565
1117 1117 a, g dbSNP:766641930
1131 1131 g, t dbSNP:763273543
1132 1132 a, c dbSNP:145673154
1138 1138 c, g dbSNP:200574824
1139 1139 c, t dbSNP:748618587
1140 1140 a, g dbSNP:774997299
1150 1150 a, c dbSNP:771478009
1165 1165 c, t dbSNP:745441531
1174 1174 a, c dbSNP:778686750
1176 1176 a, c dbSNP:770743434
1179 1179 c, t dbSNP:111353850
1180 1180 c, t dbSNP:369051842
1189 1189 a, g dbSNP:777729482
1195 1195 a, c dbSNP:756019412
1204 1204 g, t dbSNP:747353442
1210 1210 c, t dbSNP:752575373
1212 1212 c, g dbSNP:555997980
1221 1221 a, t dbSNP:754995203
1222 1222 c, t dbSNP:375321728
1226 1226 a, g dbSNP:751678511
1234 1234 a, g dbSNP:766548263
1243 1243 c, t dbSNP:758551492
1244 1244 a, g dbSNP:540208578
1251 1251 a, g dbSNP:111681798
1254 1254 a, c dbSNP:765549775
1255 1255 a, g dbSNP:762057151
1257 1257 a, g dbSNP:754264393
1261 1261 g, t dbSNP:528101301
1288 1288 a, g dbSNP:559183946
1297 1297 c, g dbSNP:531975577
1305 1305 c, t dbSNP:764532449
1308 1308 a, c dbSNP:146735451
1312 1312 -, gtccaa dbSNP:771955798
1316 1316 a, g dbSNP:201296512
1323 1323 a, g dbSNP:565071190
1333 1333 c, t dbSNP:143363077
1337 1337 a, g dbSNP:772810778
1340 1340 c, t dbSNP:764751482
1345 1345 g, t dbSNP:761543465
1351 1351 a, g dbSNP:372587710
1355 1355 a, g dbSNP:768437372
1360 1360 c, t dbSNP:746862188
1363 1363 a, c, t dbSNP:772033707
1366 1366 a, c dbSNP:745892262
1368 1368 a, g dbSNP:763437712
1383 1383 a, g dbSNP:202002859
1388 1388 c, g dbSNP:749528750
1390 1390 c, g dbSNP:777922831
1411 1411 c, t dbSNP:756526526
1414 1414 c, t dbSNP:369302647
1433 1433 c, t dbSNP:768098328
1435 1435 a, g dbSNP:755569103
1445 1445 a, g dbSNP:749849069
1447 1447 c, g dbSNP:764811179
1468 1468 a, g dbSNP:761298686
1469 1469 c, g dbSNP:151344524
1470 1470 a, c, g dbSNP:151344525
1471 1471 a, g dbSNP:554807432
1477 1477 a, c dbSNP:763782805
1483 1483 a, c, g dbSNP:140905560
1484 1484 a, g dbSNP:151344526
1486 1486 a, g dbSNP:151009833
1512 1512 a, g dbSNP:151344527
1519 1519 c, g, t dbSNP:142511319
1520 1520 c, g, t dbSNP:151344528
1521 1521 c, g dbSNP:151344530
1523 1523 a, c, g dbSNP:121909574
1527 1527 c, t dbSNP:151344531
1545 1545 a, g dbSNP:121909575
1551 1551 c, t dbSNP:781630462
1553 1553 c, t dbSNP:769053661
1559 1559 c, g dbSNP:747379877
1565 1565 c, g dbSNP:758652364
1580 1580 c, t dbSNP:35008125
1586 1586 c, t dbSNP:758856518
1612 1612 c, t dbSNP:753291798
1615 1615 c, t dbSNP:777278396
1616 1616 a, g dbSNP:755697313
1625 1625 c, t dbSNP:750843820
1646 1646 a, g dbSNP:267607108
1651 1651 c, t dbSNP:771879686
1663 1663 a, c dbSNP:745607212
1672 1672 c, t dbSNP:369463773
1675 1675 a, g dbSNP:778860533
1678 1678 c, t dbSNP:141711078
1679 1679 a, g dbSNP:377114324
1684 1684 c, t dbSNP:771617050
1685 1685 a, g dbSNP:756122879
1689 1689 c, t dbSNP:752860081
1692 1692 a, c dbSNP:144275164
1708 1708 a, c dbSNP:767678528
1723 1723 c, t dbSNP:1803117
1725 1725 a, g dbSNP:759768857
1731 1731 a, g dbSNP:751854479
1732 1732 a, g dbSNP:766726105
1735 1735 g, t dbSNP:763437006
1739 1739 a, g dbSNP:575186761
1747 1747 c, t dbSNP:770375179
1775 1775 c, t dbSNP:760066655
1786 1786 a, g dbSNP:758672228
1787 1787 c, g dbSNP:750693033
1792 1792 a, g dbSNP:765634102
1803 1803 a, t dbSNP:757626207
1804 1804 c, t dbSNP:754379873
1807 1807 c, t dbSNP:140377026
1817 1817 a, g dbSNP:759083592
1825 1825 c, t dbSNP:774029144
1826 1826 c, g dbSNP:9350373
1827 1827 g, t dbSNP:765898042
1828 1828 a, g dbSNP:762671343
1832 1832 c, t dbSNP:772807658
1834 1834 c, t dbSNP:375372321
1842 1842 a, g dbSNP:747986718
1854 1854 a, g dbSNP:776521790
1870 1870 c, t dbSNP:372082918
1884 1884 a, g dbSNP:768613709
1890 1890 c, t dbSNP:747045958
1900 1900 c, t dbSNP:780192295
1903 1903 c, t dbSNP:372299435
1906 1906 c, t dbSNP:550611281
1918 1918 c, t dbSNP:779059756
1930 1930 a, g dbSNP:757618280
1935 1935 a, g dbSNP:754293607
1937 1937 g, t dbSNP:778384375
1939 1939 c, g, t dbSNP:181105841
1942 1942 g, t dbSNP:765909703
1945 1945 c, g dbSNP:762430867
1946 1946 a, t dbSNP:750068981
1948 1948 c, g, t dbSNP:2230116
1966 1966 c, g dbSNP:200847258
1969 1969 c, t dbSNP:201494266
2008 2008 -, ctcagcaac dbSNP:760836149
2016 2016 a, c dbSNP:201591227
2017 2017 c, t dbSNP:3734391
2019 2019 a, g dbSNP:772175937
2023 2023 c, t dbSNP:745981703
2027 2027 a, c, g dbSNP:771307700
2035 2035 a, c dbSNP:749620758
2037 2037 c, t dbSNP:1803116
2043 2043 a, g dbSNP:778294642
2045 2045 a, g dbSNP:756614321
2056 2056 a, g dbSNP:374310228
2057 2057 -, gag dbSNP:773291481
2057 2057 a, g dbSNP:781601001
2076 2076 a, g dbSNP:757896248
2078 2078 c, t dbSNP:749936793
2079 2079 c, g dbSNP:764897160
2080 2080 c, t dbSNP:761472794
2081 2081 c, t dbSNP:753566744
2083 2083 c, t dbSNP:763868660
2084 2084 c, g dbSNP:760518852
2086 2086 -, c dbSNP:767561818
2086 2086 c, t dbSNP:775472363
2093 2093 c, t dbSNP:771942212
2098 2098 c, t dbSNP:371339437
2100 2100 a, c dbSNP:552520811
2103 2103 a, g dbSNP:771219549
2110 2110 -, cc dbSNP:761920926
2113 2113 c, t dbSNP:749517602
2114 2114 c, t dbSNP:778198576
2115 2115 a, c dbSNP:770263013
2117 2117 c, t dbSNP:748502364
2118 2118 a, c dbSNP:781698007
2118 2118 -, c dbSNP:774267757
2123 2123 a, g dbSNP:755465363
2127 2127 a, c dbSNP:530677405
2132 2132 c, t dbSNP:563344990
2140 2140 g, t dbSNP:542047656
2155 2155 c, t dbSNP:369680359
2158 2158 a, c dbSNP:574832806
2162 2162 a, c dbSNP:10456013
2166 2166 c, t dbSNP:541008118
2200 2200 c, t dbSNP:764664664
2201 2201 c, g dbSNP:188674648
2202 2202 a, g dbSNP:759057111
2212 2212 a, c dbSNP:558781203
2213 2213 c, t dbSNP:1461010
2224 2224 a, c dbSNP:576370374
2240 2240 g, t dbSNP:554863655
2317 2317 c, t dbSNP:536878759
2371 2371 a, g dbSNP:118042860
2397 2397 -, t dbSNP:34512481
2406 2406 -, t dbSNP:111823522
2407 2407 -, t dbSNP:546903889
2411 2411 a, c dbSNP:2763172
2416 2416 a, c dbSNP:201528167
2417 2417 a, t dbSNP:546690434
2433 2433 -, caa dbSNP:397885453
2444 2444 -, caa dbSNP:776813404
2445 2445 -, caa dbSNP:34426547
2459 2459 c, t dbSNP:9350372
2475 2475 a, g dbSNP:534571057
2487 2487 -, aaaaa dbSNP:560622395
2492 2492 a, t dbSNP:762265236
2506 2506 c, t dbSNP:570465051
2517 2517 c, t dbSNP:552459189
2533 2533 a, g dbSNP:151315569
2572 2572 -, aaaaa dbSNP:544361557
2587 2587 a, g dbSNP:146797011
2608 2608 a, c dbSNP:1045385
2644 2644 a, c dbSNP:548057203
2667 2667 a, g dbSNP:770745416
2670 2670 g, t dbSNP:749647128
2687 2687 a, c dbSNP:184322632
2691 2691 g, t dbSNP:529930646
2700 2700 -, g dbSNP:540540292
2706 2706 -, t dbSNP:773862113
2708 2708 a, t dbSNP:559552401
2724 2724 a, g dbSNP:201450721
2736 2736 a, g dbSNP:541132655
2749 2749 c, g dbSNP:576308493
2752 2752 a, g dbSNP:75419063
2775 2775 a, t dbSNP:564928565
2786 2786 a, g dbSNP:543460673
2802 2802 a, g dbSNP:181681871
2813 2813 g, t dbSNP:147713410
2818 2818 c, t dbSNP:201819112
2819 2819 -, t dbSNP:397965898
2820 2820 c, t dbSNP:74636495
2828 2828 c, t dbSNP:542820219
2829 2829 -, t dbSNP:61569279
2830 2830 -, t dbSNP:546035279
2830 2830 a, t dbSNP:78186274
2848 2848 c, t dbSNP:572623022
2874 2874 a, c dbSNP:574855862
2925 2925 g, t dbSNP:3088288
2929 2929 g, t dbSNP:2763171
2934 2934 a, g dbSNP:770287660
2941 2941 -, t dbSNP:768958142
2954 2954 g, t dbSNP:115631304
2999 2999 a, g dbSNP:2763170
3018 3018 a, g dbSNP:113256477
3029 3029 a, g dbSNP:185414193
3068 3068 c, t dbSNP:558581973
3076 3076 a, c dbSNP:537069740
3082 3082 a, g dbSNP:773868091
3087 3087 a, g dbSNP:781574382
3093 3093 c, g dbSNP:569833793
3156 3156 a, c dbSNP:755049370
3162 3162 g, t dbSNP:2857059
3164 3164 a, t dbSNP:2857060
3183 3183 c, t dbSNP:11553434
3193 3193 c, t dbSNP:747101844
3202 3202 a, c dbSNP:545023610
3233 3233 a, g dbSNP:80094467
3242 3242 a, g dbSNP:780237615
3247 3247 -, ct dbSNP:554956373
3248 3248 c, t dbSNP:193259940
3263 3263 -, tc dbSNP:150236619
3301 3301 a, g dbSNP:2763169
3304 3304 c, t dbSNP:758681260
3375 3375 c, t dbSNP:753621983
3379 3379 -, agt dbSNP:769945457
3388 3388 g, t dbSNP:186469860
3421 3421 a, g dbSNP:573067252
3453 3453 -, t dbSNP:398094002
3461 3461 -, t dbSNP:79168174
3485 3485 c, g dbSNP:763807060
3570 3570 a, g dbSNP:745977233
3597 3597 a, c dbSNP:2763168
3617 3617 g, t dbSNP:752628820
3662 3662 a, g dbSNP:552923535
3698 3698 a, g dbSNP:16893358
3724 3724 -, ttgt dbSNP:372257234

Target ORF information:

RefSeq Version NM_001032280
Organism Homo sapiens (human)
Definition Homo sapiens transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) (TFAP2A), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001032280

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
ATGTTAGTTC ACAGTTTTTC AGCCATGGAC CGTCACGACG GCACCAGCAA CGGGACGGCA 
CGGTTGCCCC AGCTGGGCAC TGTAGGTCAA TCTCCCTACA CGAGCGCCCC GCCGCTGTCC
CACACCCCCA ATGCCGACTT CCAGCCCCCA TACTTCCCCC CACCCTACCA GCCTATCTAC
CCCCAGTCGC AAGATCCTTA CTCCCACGTC AACGACCCCT ACAGCCTGAA CCCCCTGCAC
GCCCAGCCGC AGCCGCAGCA CCCAGGCTGG CCCGGCCAGA GGCAGAGCCA GGAGTCTGGG
CTCCTGCACA CGCACCGGGG GCTGCCTCAC CAGCTGTCGG GCCTGGATCC TCGCAGGGAC
TACAGGCGGC ACGAGGACCT CCTGCACGGC CCACACGCGC TCAGCTCAGG ACTCGGAGAC
CTCTCGATCC ACTCCTTACC TCACGCCATC GAGGAGGTCC CGCATGTAGA AGACCCGGGT
ATTAACATCC CAGATCAAAC TGTAATTAAG AAAGGCCCCG TGTCCCTGTC CAAGTCCAAC
AGCAATGCCG TCTCCGCCAT CCCTATTAAC AAGGACAACC TCTTCGGCGG CGTGGTGAAC
CCCAACGAAG TCTTCTGTTC AGTTCCGGGT CGCCTCTCGC TCCTCAGCTC CACCTCGAAG
TACAAGGTCA CGGTGGCGGA AGTGCAGCGG CGGCTCTCAC CACCCGAGTG TCTCAACGCG
TCGCTGCTGG GCGGAGTGCT CCGGAGGGCG AAGTCTAAAA ATGGAGGAAG ATCTTTAAGA
GAAAAACTGG ACAAAATAGG ATTAAATCTG CCTGCAGGGA GACGTAAAGC TGCCAACGTT
ACCCTGCTCA CATCACTAGT AGAGGGAGAA GCTGTCCACC TAGCCAGGGA CTTTGGGTAC
GTGTGCGAAA CCGAATTTCC TGCCAAAGCA GTAGCTGAAT TTCTCAACCG ACAACATTCC
GATCCCAATG AGCAAGTGAC AAGAAAAAAC ATGCTCCTGG CTACAAAACA GATATGCAAA
GAGTTCACCG ACCTGCTGGC TCAGGACCGA TCTCCCCTGG GGAACTCACG GCCCAACCCC
ATCCTGGAGC CCGGCATCCA GAGCTGCTTG ACCCACTTCA ACCTCATCTC CCACGGCTTC
GGCAGCCCCG CGGTGTGTGC CGCGGTCACG GCCCTGCAGA ACTATCTCAC CGAGGCCCTC
AAGGCCATGG ACAAAATGTA CCTCAGCAAC AACCCCAACA GCCACACGGA CAACAACGCC
AAAAGCAGTG ACAAAGAGGA GAAGCACAGA AAGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu19280
Accession Version NM_001042425.1
Sequence Information ORF Nucleotide Sequence (Length: 1302bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product transcription factor AP-2-alpha isoform c
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from CB990517.1, X52611.1 and AL138885.21. Summary: The protein encoded by this gene is a transcription factor that binds the consensus sequence 5'-GCCNNNGGC-3'. The encoded protein functions as either a homodimer or as a heterodimer with similar family members. This protein activates the transcription of some genes while inhibiting the transcription of others. Defects in this gene are a cause of branchiooculofacial syndrome (BOFS). Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Dec 2009]. Transcript Variant: This variant (3) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (c) has a shorter and distinct N-terminus compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA2147596 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
ATGTCCATAC TTGCCAAAAT GGGGGACTGG CAGGACCGTC ACGACGGCAC CAGCAACGGG 
ACGGCACGGT TGCCCCAGCT GGGCACTGTA GGTCAATCTC CCTACACGAG CGCCCCGCCG
CTGTCCCACA CCCCCAATGC CGACTTCCAG CCCCCATACT TCCCCCCACC CTACCAGCCT
ATCTACCCCC AGTCGCAAGA TCCTTACTCC CACGTCAACG ACCCCTACAG CCTGAACCCC
CTGCACGCCC AGCCGCAGCC GCAGCACCCA GGCTGGCCCG GCCAGAGGCA GAGCCAGGAG
TCTGGGCTCC TGCACACGCA CCGGGGGCTG CCTCACCAGC TGTCGGGCCT GGATCCTCGC
AGGGACTACA GGCGGCACGA GGACCTCCTG CACGGCCCAC ACGCGCTCAG CTCAGGACTC
GGAGACCTCT CGATCCACTC CTTACCTCAC GCCATCGAGG AGGTCCCGCA TGTAGAAGAC
CCGGGTATTA ACATCCCAGA TCAAACTGTA ATTAAGAAAG GCCCCGTGTC CCTGTCCAAG
TCCAACAGCA ATGCCGTCTC CGCCATCCCT ATTAACAAGG ACAACCTCTT CGGCGGCGTG
GTGAACCCCA ACGAAGTCTT CTGTTCAGTT CCGGGTCGCC TCTCGCTCCT CAGCTCCACC
TCGAAGTACA AGGTCACGGT GGCGGAAGTG CAGCGGCGGC TCTCACCACC CGAGTGTCTC
AACGCGTCGC TGCTGGGCGG AGTGCTCCGG AGGGCGAAGT CTAAAAATGG AGGAAGATCT
TTAAGAGAAA AACTGGACAA AATAGGATTA AATCTGCCTG CAGGGAGACG TAAAGCTGCC
AACGTTACCC TGCTCACATC ACTAGTAGAG GGAGAAGCTG TCCACCTAGC CAGGGACTTT
GGGTACGTGT GCGAAACCGA ATTTCCTGCC AAAGCAGTAG CTGAATTTCT CAACCGACAA
CATTCCGATC CCAATGAGCA AGTGACAAGA AAAAACATGC TCCTGGCTAC AAAACAGATA
TGCAAAGAGT TCACCGACCT GCTGGCTCAG GACCGATCTC CCCTGGGGAA CTCACGGCCC
AACCCCATCC TGGAGCCCGG CATCCAGAGC TGCTTGACCC ACTTCAACCT CATCTCCCAC
GGCTTCGGCA GCCCCGCGGT GTGTGCCGCG GTCACGGCCC TGCAGAACTA TCTCACCGAG
GCCCTCAAGG CCATGGACAA AATGTACCTC AGCAACAACC CCAACAGCCA CACGGACAAC
AACGCCAAAA GCAGTGACAA AGAGGAGAAG CACAGAAAGT GA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_001035890.1
CDS115..1416
Misc Feature(1)727..1344(+)
Exon (1)1..147
Gene:TFAP2A
Gene Synonym:
Exon (2)148..582
Gene:TFAP2A
Gene Synonym:
Exon (3)583..634
Gene:TFAP2A
Gene Synonym:
Exon (4)635..866
Gene:TFAP2A
Gene Synonym:
Exon (5)867..985
Gene:TFAP2A
Gene Synonym:
Exon (6)986..1127
Gene:TFAP2A
Gene Synonym:
Exon (7)1128..3150
Gene:TFAP2A
Gene Synonym:
Translation
Position Chain Variation Link
47 47 g, t dbSNP:188425674
66 66 c, t dbSNP:368990128
71 71 a, g dbSNP:780793965
72 72 c, t dbSNP:374766084
75 75 a, g dbSNP:751456302
76 76 c, t dbSNP:371444949
82 82 a, g dbSNP:758461295
84 84 a, g dbSNP:201195699
85 85 a, g dbSNP:202033105
95 95 g, t dbSNP:762053754
96 96 c, t dbSNP:777002161
97 97 -, c dbSNP:747120472
98 98 a, g dbSNP:764375828
100 100 g, t dbSNP:761175309
111 111 c, t dbSNP:140181319
118 118 c, t dbSNP:772759043
121 121 a, c dbSNP:762523527
123 123 a, t dbSNP:772884092
130 130 a, g dbSNP:769526609
133 133 a, t dbSNP:747769835
137 137 a, g dbSNP:780973352
161 161 a, g, t dbSNP:143258135
183 183 a, g dbSNP:768948369
199 199 a, g dbSNP:9368354
203 203 g, t dbSNP:780216169
206 206 g, t dbSNP:772479857
207 207 g, t dbSNP:746272068
212 212 c, t dbSNP:779448987
213 213 a, t dbSNP:757798850
222 222 g, t dbSNP:752157129
226 226 g, t dbSNP:373246714
235 235 c, t dbSNP:754562525
236 236 c, t dbSNP:751224702
237 237 a, g dbSNP:149126243
242 242 a, c dbSNP:762787739
244 244 a, c dbSNP:750226796
245 245 c, g dbSNP:765183722
248 248 c, t dbSNP:761863117
249 249 -, cc dbSNP:753073720
250 250 a, c dbSNP:776792762
251 251 a, g dbSNP:527785340
253 253 c, g dbSNP:760904143
257 257 a, c dbSNP:775764363
259 259 c, t dbSNP:772228476
262 262 -, a dbSNP:34436436
267 267 c, t dbSNP:746209784
270 270 a, c dbSNP:779173083
273 273 c, t dbSNP:771371649
275 275 c, t dbSNP:749803917
281 281 a, c dbSNP:778321721
282 282 a, c dbSNP:754476051
287 287 a, c dbSNP:746550070
291 291 a, g dbSNP:779727040
299 299 a, g dbSNP:758018662
304 304 c, g dbSNP:750185451
309 309 a, g dbSNP:765135263
315 315 a, t dbSNP:560684169
316 316 a, c dbSNP:753822419
322 322 a, t dbSNP:764184708
324 324 c, g dbSNP:760782033
333 333 c, g dbSNP:775468691
342 342 c, t dbSNP:767736500
353 353 c, t dbSNP:200131527
354 354 c, t dbSNP:774713482
355 355 c, g dbSNP:376101872
360 360 a, c, t dbSNP:545067807
369 369 a, g dbSNP:773687604
375 375 a, g dbSNP:770326832
391 391 c, t dbSNP:746489683
392 392 c, t dbSNP:779455245
393 393 c, g dbSNP:758008816
399 399 c, g dbSNP:372468982
401 401 c, g dbSNP:778774564
408 408 c, g dbSNP:757104358
418 418 c, g dbSNP:753730365
424 424 c, t dbSNP:764088571
425 425 a, t dbSNP:756034130
438 438 a, g dbSNP:138225261
439 439 a, g dbSNP:767502053
442 442 c, t dbSNP:563009991
456 456 a, g dbSNP:544933565
459 459 a, g dbSNP:766641930
473 473 g, t dbSNP:763273543
474 474 a, c dbSNP:145673154
480 480 c, g dbSNP:200574824
481 481 c, t dbSNP:748618587
482 482 a, g dbSNP:774997299
492 492 a, c dbSNP:771478009
507 507 c, t dbSNP:745441531
516 516 a, c dbSNP:778686750
518 518 a, c dbSNP:770743434
521 521 c, t dbSNP:111353850
522 522 c, t dbSNP:369051842
531 531 a, g dbSNP:777729482
537 537 a, c dbSNP:756019412
546 546 g, t dbSNP:747353442
552 552 c, t dbSNP:752575373
554 554 c, g dbSNP:555997980
563 563 a, t dbSNP:754995203
564 564 c, t dbSNP:375321728
568 568 a, g dbSNP:751678511
576 576 a, g dbSNP:766548263
585 585 c, t dbSNP:758551492
586 586 a, g dbSNP:540208578
593 593 a, g dbSNP:111681798
596 596 a, c dbSNP:765549775
597 597 a, g dbSNP:762057151
599 599 a, g dbSNP:754264393
603 603 g, t dbSNP:528101301
630 630 a, g dbSNP:559183946
639 639 c, g dbSNP:531975577
647 647 c, t dbSNP:764532449
650 650 a, c dbSNP:146735451
654 654 -, gtccaa dbSNP:771955798
658 658 a, g dbSNP:201296512
665 665 a, g dbSNP:565071190
675 675 c, t dbSNP:143363077
679 679 a, g dbSNP:772810778
682 682 c, t dbSNP:764751482
687 687 g, t dbSNP:761543465
693 693 a, g dbSNP:372587710
697 697 a, g dbSNP:768437372
702 702 c, t dbSNP:746862188
705 705 a, c, t dbSNP:772033707
708 708 a, c dbSNP:745892262
710 710 a, g dbSNP:763437712
725 725 a, g dbSNP:202002859
730 730 c, g dbSNP:749528750
732 732 c, g dbSNP:777922831
753 753 c, t dbSNP:756526526
756 756 c, t dbSNP:369302647
775 775 c, t dbSNP:768098328
777 777 a, g dbSNP:755569103
787 787 a, g dbSNP:749849069
789 789 c, g dbSNP:764811179
810 810 a, g dbSNP:761298686
811 811 c, g dbSNP:151344524
812 812 a, c, g dbSNP:151344525
813 813 a, g dbSNP:554807432
819 819 a, c dbSNP:763782805
825 825 a, c, g dbSNP:140905560
826 826 a, g dbSNP:151344526
828 828 a, g dbSNP:151009833
854 854 a, g dbSNP:151344527
861 861 c, g, t dbSNP:142511319
862 862 c, g, t dbSNP:151344528
863 863 c, g dbSNP:151344530
865 865 a, c, g dbSNP:121909574
869 869 c, t dbSNP:151344531
887 887 a, g dbSNP:121909575
893 893 c, t dbSNP:781630462
895 895 c, t dbSNP:769053661
901 901 c, g dbSNP:747379877
907 907 c, g dbSNP:758652364
922 922 c, t dbSNP:35008125
928 928 c, t dbSNP:758856518
954 954 c, t dbSNP:753291798
957 957 c, t dbSNP:777278396
958 958 a, g dbSNP:755697313
967 967 c, t dbSNP:750843820
988 988 a, g dbSNP:267607108
993 993 c, t dbSNP:771879686
1005 1005 a, c dbSNP:745607212
1014 1014 c, t dbSNP:369463773
1017 1017 a, g dbSNP:778860533
1020 1020 c, t dbSNP:141711078
1021 1021 a, g dbSNP:377114324
1026 1026 c, t dbSNP:771617050
1027 1027 a, g dbSNP:756122879
1031 1031 c, t dbSNP:752860081
1034 1034 a, c dbSNP:144275164
1050 1050 a, c dbSNP:767678528
1065 1065 c, t dbSNP:1803117
1067 1067 a, g dbSNP:759768857
1073 1073 a, g dbSNP:751854479
1074 1074 a, g dbSNP:766726105
1077 1077 g, t dbSNP:763437006
1081 1081 a, g dbSNP:575186761
1089 1089 c, t dbSNP:770375179
1117 1117 c, t dbSNP:760066655
1128 1128 a, g dbSNP:758672228
1129 1129 c, g dbSNP:750693033
1134 1134 a, g dbSNP:765634102
1145 1145 a, t dbSNP:757626207
1146 1146 c, t dbSNP:754379873
1149 1149 c, t dbSNP:140377026
1159 1159 a, g dbSNP:759083592
1167 1167 c, t dbSNP:774029144
1168 1168 c, g dbSNP:9350373
1169 1169 g, t dbSNP:765898042
1170 1170 a, g dbSNP:762671343
1174 1174 c, t dbSNP:772807658
1176 1176 c, t dbSNP:375372321
1184 1184 a, g dbSNP:747986718
1196 1196 a, g dbSNP:776521790
1212 1212 c, t dbSNP:372082918
1226 1226 a, g dbSNP:768613709
1232 1232 c, t dbSNP:747045958
1242 1242 c, t dbSNP:780192295
1245 1245 c, t dbSNP:372299435
1248 1248 c, t dbSNP:550611281
1260 1260 c, t dbSNP:779059756
1272 1272 a, g dbSNP:757618280
1277 1277 a, g dbSNP:754293607
1279 1279 g, t dbSNP:778384375
1281 1281 c, g, t dbSNP:181105841
1284 1284 g, t dbSNP:765909703
1287 1287 c, g dbSNP:762430867
1288 1288 a, t dbSNP:750068981
1290 1290 c, g, t dbSNP:2230116
1308 1308 c, g dbSNP:200847258
1311 1311 c, t dbSNP:201494266
1350 1350 -, ctcagcaac dbSNP:760836149
1358 1358 a, c dbSNP:201591227
1359 1359 c, t dbSNP:3734391
1361 1361 a, g dbSNP:772175937
1365 1365 c, t dbSNP:745981703
1369 1369 a, c, g dbSNP:771307700
1377 1377 a, c dbSNP:749620758
1379 1379 c, t dbSNP:1803116
1385 1385 a, g dbSNP:778294642
1387 1387 a, g dbSNP:756614321
1398 1398 a, g dbSNP:374310228
1399 1399 -, gag dbSNP:773291481
1399 1399 a, g dbSNP:781601001
1418 1418 a, g dbSNP:757896248
1420 1420 c, t dbSNP:749936793
1421 1421 c, g dbSNP:764897160
1422 1422 c, t dbSNP:761472794
1423 1423 c, t dbSNP:753566744
1425 1425 c, t dbSNP:763868660
1426 1426 c, g dbSNP:760518852
1428 1428 -, c dbSNP:767561818
1428 1428 c, t dbSNP:775472363
1435 1435 c, t dbSNP:771942212
1440 1440 c, t dbSNP:371339437
1442 1442 a, c dbSNP:552520811
1445 1445 a, g dbSNP:771219549
1452 1452 -, cc dbSNP:761920926
1455 1455 c, t dbSNP:749517602
1456 1456 c, t dbSNP:778198576
1457 1457 a, c dbSNP:770263013
1459 1459 c, t dbSNP:748502364
1460 1460 a, c dbSNP:781698007
1460 1460 -, c dbSNP:774267757
1465 1465 a, g dbSNP:755465363
1469 1469 a, c dbSNP:530677405
1474 1474 c, t dbSNP:563344990
1482 1482 g, t dbSNP:542047656
1497 1497 c, t dbSNP:369680359
1500 1500 a, c dbSNP:574832806
1504 1504 a, c dbSNP:10456013
1508 1508 c, t dbSNP:541008118
1542 1542 c, t dbSNP:764664664
1543 1543 c, g dbSNP:188674648
1544 1544 a, g dbSNP:759057111
1554 1554 a, c dbSNP:558781203
1555 1555 c, t dbSNP:1461010
1566 1566 a, c dbSNP:576370374
1582 1582 g, t dbSNP:554863655
1659 1659 c, t dbSNP:536878759
1713 1713 a, g dbSNP:118042860
1739 1739 -, t dbSNP:34512481
1748 1748 -, t dbSNP:111823522
1749 1749 -, t dbSNP:546903889
1753 1753 a, c dbSNP:2763172
1758 1758 a, c dbSNP:201528167
1759 1759 a, t dbSNP:546690434
1775 1775 -, caa dbSNP:397885453
1786 1786 -, caa dbSNP:776813404
1787 1787 -, caa dbSNP:34426547
1801 1801 c, t dbSNP:9350372
1817 1817 a, g dbSNP:534571057
1829 1829 -, aaaaa dbSNP:560622395
1834 1834 a, t dbSNP:762265236
1848 1848 c, t dbSNP:570465051
1859 1859 c, t dbSNP:552459189
1875 1875 a, g dbSNP:151315569
1914 1914 -, aaaaa dbSNP:544361557
1929 1929 a, g dbSNP:146797011
1950 1950 a, c dbSNP:1045385
1986 1986 a, c dbSNP:548057203
2009 2009 a, g dbSNP:770745416
2012 2012 g, t dbSNP:749647128
2029 2029 a, c dbSNP:184322632
2033 2033 g, t dbSNP:529930646
2042 2042 -, g dbSNP:540540292
2048 2048 -, t dbSNP:773862113
2050 2050 a, t dbSNP:559552401
2066 2066 a, g dbSNP:201450721
2078 2078 a, g dbSNP:541132655
2091 2091 c, g dbSNP:576308493
2094 2094 a, g dbSNP:75419063
2117 2117 a, t dbSNP:564928565
2128 2128 a, g dbSNP:543460673
2144 2144 a, g dbSNP:181681871
2155 2155 g, t dbSNP:147713410
2160 2160 c, t dbSNP:201819112
2161 2161 -, t dbSNP:397965898
2162 2162 c, t dbSNP:74636495
2170 2170 c, t dbSNP:542820219
2171 2171 -, t dbSNP:61569279
2172 2172 -, t dbSNP:546035279
2172 2172 a, t dbSNP:78186274
2190 2190 c, t dbSNP:572623022
2216 2216 a, c dbSNP:574855862
2267 2267 g, t dbSNP:3088288
2271 2271 g, t dbSNP:2763171
2276 2276 a, g dbSNP:770287660
2283 2283 -, t dbSNP:768958142
2296 2296 g, t dbSNP:115631304
2341 2341 a, g dbSNP:2763170
2360 2360 a, g dbSNP:113256477
2371 2371 a, g dbSNP:185414193
2410 2410 c, t dbSNP:558581973
2418 2418 a, c dbSNP:537069740
2424 2424 a, g dbSNP:773868091
2429 2429 a, g dbSNP:781574382
2435 2435 c, g dbSNP:569833793
2498 2498 a, c dbSNP:755049370
2504 2504 g, t dbSNP:2857059
2506 2506 a, t dbSNP:2857060
2525 2525 c, t dbSNP:11553434
2535 2535 c, t dbSNP:747101844
2544 2544 a, c dbSNP:545023610
2575 2575 a, g dbSNP:80094467
2584 2584 a, g dbSNP:780237615
2589 2589 -, ct dbSNP:554956373
2590 2590 c, t dbSNP:193259940
2605 2605 -, tc dbSNP:150236619
2643 2643 a, g dbSNP:2763169
2646 2646 c, t dbSNP:758681260
2717 2717 c, t dbSNP:753621983
2721 2721 -, agt dbSNP:769945457
2730 2730 g, t dbSNP:186469860
2763 2763 a, g dbSNP:573067252
2795 2795 -, t dbSNP:398094002
2803 2803 -, t dbSNP:79168174
2827 2827 c, g dbSNP:763807060
2912 2912 a, g dbSNP:745977233
2939 2939 a, c dbSNP:2763168
2959 2959 g, t dbSNP:752628820
3004 3004 a, g dbSNP:552923535
3040 3040 a, g dbSNP:16893358
3066 3066 -, ttgt dbSNP:372257234

Target ORF information:

RefSeq Version NM_001042425
Organism Homo sapiens (human)
Definition Homo sapiens transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) (TFAP2A), transcript variant 3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001042425

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
ATGTCCATAC TTGCCAAAAT GGGGGACTGG CAGGACCGTC ACGACGGCAC CAGCAACGGG 
ACGGCACGGT TGCCCCAGCT GGGCACTGTA GGTCAATCTC CCTACACGAG CGCCCCGCCG
CTGTCCCACA CCCCCAATGC CGACTTCCAG CCCCCATACT TCCCCCCACC CTACCAGCCT
ATCTACCCCC AGTCGCAAGA TCCTTACTCC CACGTCAACG ACCCCTACAG CCTGAACCCC
CTGCACGCCC AGCCGCAGCC GCAGCACCCA GGCTGGCCCG GCCAGAGGCA GAGCCAGGAG
TCTGGGCTCC TGCACACGCA CCGGGGGCTG CCTCACCAGC TGTCGGGCCT GGATCCTCGC
AGGGACTACA GGCGGCACGA GGACCTCCTG CACGGCCCAC ACGCGCTCAG CTCAGGACTC
GGAGACCTCT CGATCCACTC CTTACCTCAC GCCATCGAGG AGGTCCCGCA TGTAGAAGAC
CCGGGTATTA ACATCCCAGA TCAAACTGTA ATTAAGAAAG GCCCCGTGTC CCTGTCCAAG
TCCAACAGCA ATGCCGTCTC CGCCATCCCT ATTAACAAGG ACAACCTCTT CGGCGGCGTG
GTGAACCCCA ACGAAGTCTT CTGTTCAGTT CCGGGTCGCC TCTCGCTCCT CAGCTCCACC
TCGAAGTACA AGGTCACGGT GGCGGAAGTG CAGCGGCGGC TCTCACCACC CGAGTGTCTC
AACGCGTCGC TGCTGGGCGG AGTGCTCCGG AGGGCGAAGT CTAAAAATGG AGGAAGATCT
TTAAGAGAAA AACTGGACAA AATAGGATTA AATCTGCCTG CAGGGAGACG TAAAGCTGCC
AACGTTACCC TGCTCACATC ACTAGTAGAG GGAGAAGCTG TCCACCTAGC CAGGGACTTT
GGGTACGTGT GCGAAACCGA ATTTCCTGCC AAAGCAGTAG CTGAATTTCT CAACCGACAA
CATTCCGATC CCAATGAGCA AGTGACAAGA AAAAACATGC TCCTGGCTAC AAAACAGATA
TGCAAAGAGT TCACCGACCT GCTGGCTCAG GACCGATCTC CCCTGGGGAA CTCACGGCCC
AACCCCATCC TGGAGCCCGG CATCCAGAGC TGCTTGACCC ACTTCAACCT CATCTCCCAC
GGCTTCGGCA GCCCCGCGGT GTGTGCCGCG GTCACGGCCC TGCAGAACTA TCTCACCGAG
GCCCTCAAGG CCATGGACAA AATGTACCTC AGCAACAACC CCAACAGCCA CACGGACAAC
AACGCCAAAA GCAGTGACAA AGAGGAGAAG CACAGAAAGT GA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.