The following TGFBI gene sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TGFBI gene which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
||ORF Nucleotide Sequence (Length: 2052bp)
||pcDNA3.1+/C-(K)DYK or customized vector
|Tag on pcDNA3.1+/C-(K)DYK
||C terminal DYKDDDDK tags
|ORF Insert Method
||CloneEZ® Seamless cloning technology
||Homo sapiens (human)
||transforming growth factor-beta-induced protein ig-h3 precursor
||REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from DA051240.1, BC000097.2 and
This sequence is a reference standard in the RefSeqGene project.
On Mar 21, 2008 this sequence version replaced gi:4507466.
Summary: This gene encodes an RGD-containing protein that binds to
type I, II and IV collagens. The RGD motif is found in many
extracellular matrix proteins modulating cell adhesion and serves
as a ligand recognition sequence for several integrins. This
protein plays a role in cell-collagen interactions and may be
involved in endochondrial bone formation in cartilage. The protein
is induced by transforming growth factor-beta and acts to inhibit
cell adhesion. Mutations in this gene are associated with multiple
types of corneal dystrophy. [provided by RefSeq, Jul 2008].
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
Transcript exon combination :: BC000097.2, AK094581.1 [ECO:0000332]
RNAseq introns :: single sample supports all introns
COMPLETENESS: complete on the 3' end.