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TGFBI transforming growth factor, beta-induced, 68kDa [Homo sapiens (human)]

Gene Symbol TGFBI
Entrez Gene ID 7045
Full Name transforming growth factor, beta-induced, 68kDa
Synonyms BIGH3, CDB1, CDG2, CDGG1, CSD, CSD1, CSD2, CSD3, EBMD, LCD1
General protein information
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

5

5q31

Summary This gene encodes an RGD-containing protein that binds to type I, II and IV collagens. The RGD motif is found in many extracellular matrix proteins modulating cell adhesion and serves as a ligand recognition sequence for several integrins. This protein plays a role in cell-collagen interactions and may be involved in endochondrial bone formation in cartilage. The protein is induced by transforming growth factor-beta and acts to inhibit cell adhesion. Mutations in this gene are associated with multiple types of corneal dystrophy. [provided by RefSeq, Jul 2008]. lac of sum
Disorder MIM:

601692

Disorder Html: Corneal dystrophy, Groenouw type I, 121900 (3); Corneal dystrophy,





The following TGFBI gene sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TGFBI gene which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu26539 NM_000358 Homo sapiens transforming growth factor, beta-induced, 68kDa (TGFBI), mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$99

*Business Day
**You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.


CloneID OHu26539
Accession Version NM_000358.2 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 2052bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector Document: User manual_GenEZ ORF Clone Products.pdf (pdf)
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags Document: MSDS_GenEZ ORF Clone Products.pdf (pdf)
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear Document: OHu26539D_COA.pdf (pdf)
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product transforming growth factor-beta-induced protein ig-h3 precursor
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA051240.1, BC000097.2 and M77349.1. This sequence is a reference standard in the RefSeqGene project. On Mar 21, 2008 this sequence version replaced gi:4507466. Summary: This gene encodes an RGD-containing protein that binds to type I, II and IV collagens. The RGD motif is found in many extracellular matrix proteins modulating cell adhesion and serves as a ligand recognition sequence for several integrins. This protein plays a role in cell-collagen interactions and may be involved in endochondrial bone formation in cartilage. The protein is induced by transforming growth factor-beta and acts to inhibit cell adhesion. Mutations in this gene are associated with multiple types of corneal dystrophy. [provided by RefSeq, Jul 2008]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC000097.2, AK094581.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
ATGGCGCTCT TCGTGCGGCT GCTGGCTCTC GCCCTGGCTC TGGCCCTGGG CCCCGCCGCG 
ACCCTGGCGG GTCCCGCCAA GTCGCCCTAC CAGCTGGTGC TGCAGCACAG CAGGCTCCGG
GGCCGCCAGC ACGGCCCCAA CGTGTGTGCT GTGCAGAAGG TTATTGGCAC TAATAGGAAG
TACTTCACCA ACTGCAAGCA GTGGTACCAA AGGAAAATCT GTGGCAAATC AACAGTCATC
AGCTACGAGT GCTGTCCTGG ATATGAAAAG GTCCCTGGGG AGAAGGGCTG TCCAGCAGCC
CTACCACTCT CAAACCTTTA CGAGACCCTG GGAGTCGTTG GATCCACCAC CACTCAGCTG
TACACGGACC GCACGGAGAA GCTGAGGCCT GAGATGGAGG GGCCCGGCAG CTTCACCATC
TTCGCCCCTA GCAACGAGGC CTGGGCCTCC TTGCCAGCTG AAGTGCTGGA CTCCCTGGTC
AGCAATGTCA ACATTGAGCT GCTCAATGCC CTCCGCTACC ATATGGTGGG CAGGCGAGTC
CTGACTGATG AGCTGAAACA CGGCATGACC CTCACCTCTA TGTACCAGAA TTCCAACATC
CAGATCCACC ACTATCCTAA TGGGATTGTA ACTGTGAACT GTGCCCGGCT GCTGAAAGCC
GACCACCATG CAACCAACGG GGTGGTGCAC CTCATCGATA AGGTCATCTC CACCATCACC
AACAACATCC AGCAGATCAT TGAGATCGAG GACACCTTTG AGACCCTTCG GGCTGCTGTG
GCTGCATCAG GGCTCAACAC GATGCTTGAA GGTAACGGCC AGTACACGCT TTTGGCCCCG
ACCAATGAGG CCTTCGAGAA GATCCCTAGT GAGACTTTGA ACCGTATCCT GGGCGACCCA
GAAGCCCTGA GAGACCTGCT GAACAACCAC ATCTTGAAGT CAGCTATGTG TGCTGAAGCC
ATCGTTGCGG GGCTGTCTGT AGAGACCCTG GAGGGCACGA CACTGGAGGT GGGCTGCAGC
GGGGACATGC TCACTATCAA CGGGAAGGCG ATCATCTCCA ATAAAGACAT CCTAGCCACC
AACGGGGTGA TCCACTACAT TGATGAGCTA CTCATCCCAG ACTCAGCCAA GACACTATTT
GAATTGGCTG CAGAGTCTGA TGTGTCCACA GCCATTGACC TTTTCAGACA AGCCGGCCTC
GGCAATCATC TCTCTGGAAG TGAGCGGTTG ACCCTCCTGG CTCCCCTGAA TTCTGTATTC
AAAGATGGAA CCCCTCCAAT TGATGCCCAT ACAAGGAATT TGCTTCGGAA CCACATAATT
AAAGACCAGC TGGCCTCTAA GTATCTGTAC CATGGACAGA CCCTGGAAAC TCTGGGCGGC
AAAAAACTGA GAGTTTTTGT TTATCGTAAT AGCCTCTGCA TTGAGAACAG CTGCATCGCG
GCCCACGACA AGAGGGGGAG GTACGGGACC CTGTTCACGA TGGACCGGGT GCTGACCCCC
CCAATGGGGA CTGTCATGGA TGTCCTGAAG GGAGACAATC GCTTTAGCAT GCTGGTAGCT
GCCATCCAGT CTGCAGGACT GACGGAGACC CTCAACCGGG AAGGAGTCTA CACAGTCTTT
GCTCCCACAA ATGAAGCCTT CCGAGCCCTG CCACCAAGAG AACGGAGCAG ACTCTTGGGA
GATGCCAAGG AACTTGCCAA CATCCTGAAA TACCACATTG GTGATGAAAT CCTGGTTAGC
GGAGGCATCG GGGCCCTGGT GCGGCTAAAG TCTCTCCAAG GTGACAAGCT GGAAGTCAGC
TTGAAAAACA ATGTGGTGAG TGTCAACAAG GAGCCTGTTG CCGAGCCTGA CATCATGGCC
ACAAATGGCG TGGTCCATGT CATCACCAAT GTTCTGCAGC CTCCAGCCAA CAGACCTCAG
GAAAGAGGGG ATGAACTTGC AGACTCTGCG CTTGAGATCT TCAAACAAGC ATCAGCGTTT
TCCAGGGCTT CCCAGAGGTC TGTGCGACTA GCCCCTGTCT ATCAAAAGTT ATTAGAGAGG
ATGAAGCATT AG
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_000349.1
CDS162..2213
Misc Feature(1)132..134(+)
Misc Feature(2)294..437(+)
Misc Feature(3)558..869(+)
Misc Feature(4)918..1280(+)
Misc Feature(5)1317..1661(+)
Misc Feature(6)1701..2063(+)
Misc Feature(7)2085..2093(+)
Exon (1)1..295
Gene:TGFBI
Gene Synonym:
Exon (2)296..394
Gene:TGFBI
Gene Synonym:
Exon (3)395..459
Gene:TGFBI
Gene Synonym:
Exon (4)460..620
Gene:TGFBI
Gene Synonym:
Exon (5)621..785
Gene:TGFBI
Gene Synonym:
Exon (6)786..932
Gene:TGFBI
Gene Synonym:
Exon (7)933..1074
Gene:TGFBI
Gene Synonym:
Exon (8)1075..1287
Gene:TGFBI
Gene Synonym:
Exon (9)1288..1425
Gene:TGFBI
Gene Synonym:
Exon (10)1426..1571
Gene:TGFBI
Gene Synonym:
Exon (11)1572..1708
Gene:TGFBI
Gene Synonym:
Exon (12)1709..1839
Gene:TGFBI
Gene Synonym:
Exon (13)1840..1964
Gene:TGFBI
Gene Synonym:
Exon (14)1965..2067
Gene:TGFBI
Gene Synonym:
Exon (15)2068..2147
Gene:TGFBI
Gene Synonym:
Exon (16)2148..2172
Gene:TGFBI
Gene Synonym:
Exon (17)2173..2805
Gene:TGFBI
Gene Synonym:
Translation
Position Chain Variation Link
38 38 a, c dbSNP:562269545
50 50 c, t dbSNP:368738731
61 61 c, t dbSNP:577683426
78 78 g, t dbSNP:545050658
101 101 c, g dbSNP:774898698
121 121 a, c dbSNP:753940748
125 125 c, g dbSNP:755265459
130 130 c, g dbSNP:779085457
156 156 c, g dbSNP:748267766
163 163 c, t dbSNP:772104901
177 177 a, c dbSNP:560533561
191 191 -, gccctggctctg dbSNP:751354896
200 200 c, t dbSNP:746806677
211 211 c, g, t dbSNP:770699457
214 214 c, t dbSNP:759135120
216 216 a, g dbSNP:769461769
221 221 c, g dbSNP:527841882
229 229 a, c dbSNP:774946059
230 230 g, t dbSNP:762495959
238 238 c, t dbSNP:767993906
261 261 c, t dbSNP:6866553
280 280 c, g dbSNP:755376272
293 293 c, t dbSNP:750955331
301 301 a, g dbSNP:745697616
302 302 c, t dbSNP:368854767
303 303 -, gtgt dbSNP:761604290
311 311 a, t dbSNP:769410908
317 317 a, g dbSNP:56099530
328 328 a, g dbSNP:775178833
342 342 c, t dbSNP:748787871
351 351 a, c dbSNP:767980992
352 352 a, g dbSNP:773924435
372 372 a, g dbSNP:761036803
374 374 a, g dbSNP:766939734
377 377 a, g dbSNP:372182906
385 385 a, g dbSNP:376708827
394 394 c, t dbSNP:760027441
395 395 a, g dbSNP:768375107
401 401 c, t dbSNP:370117299
407 407 c, t dbSNP:373533246
411 411 c, t dbSNP:771320956
416 416 c, t dbSNP:777335010
417 417 c, g dbSNP:548789955
434 434 c, t dbSNP:759976271
449 449 c, t dbSNP:770218208
454 454 c, t dbSNP:776013046
468 468 a, c dbSNP:774697241
480 480 c, t dbSNP:745312980
482 482 c, t dbSNP:761942644
483 483 a, g dbSNP:188322933
487 487 c, t dbSNP:750523055
488 488 c, t dbSNP:370398713
492 492 a, g dbSNP:760563798
495 495 a, g dbSNP:766343295
497 497 c, t dbSNP:577217638
498 498 a, g, t dbSNP:757933370
502 502 c, g dbSNP:752328722
507 507 a, g dbSNP:374678658
508 508 c, g dbSNP:777372145
523 523 a, g dbSNP:368481276
524 524 a, c dbSNP:770397832
526 526 c, t dbSNP:780759366
527 527 a, g dbSNP:749608724
528 528 c, g dbSNP:541270955
530 530 a, c, t dbSNP:774589411
531 531 a, c, t dbSNP:121909210
532 532 a, g, t dbSNP:121909211
535 535 c, g, t dbSNP:372436914
536 536 a, g dbSNP:559129656
542 542 a, g dbSNP:759397924
548 548 c, g dbSNP:765026368
554 554 g, t dbSNP:199604416
556 556 a, t dbSNP:758087436
562 562 a, g dbSNP:574362916
563 563 a, g dbSNP:541593603
565 565 c, t dbSNP:377011307
566 566 c, t dbSNP:180743451
567 567 a, g dbSNP:749742157
580 580 c, t dbSNP:367994294
584 584 c, t dbSNP:779817855
585 585 a, g dbSNP:779294634
592 592 a, g dbSNP:371581568
596 596 c, t dbSNP:772258752
597 597 a, g dbSNP:773479467
601 601 a, c dbSNP:747088571
607 607 c, t dbSNP:76212104
608 608 c, g dbSNP:376089468
615 615 a, c dbSNP:759471032
623 623 a, g dbSNP:767113829
627 627 a, c dbSNP:749925738
628 628 c, t dbSNP:760160548
630 630 a, g, t dbSNP:765769059
632 632 c, g dbSNP:558785543
635 635 c, t dbSNP:778064102
647 647 c, t dbSNP:373003334
655 655 c, t dbSNP:182124708
657 657 a, g dbSNP:370299079
665 665 c, t dbSNP:745951543
675 675 c, t dbSNP:374172528
676 676 a, g dbSNP:780291187
684 684 a, g dbSNP:368580532
697 697 a, g dbSNP:371119133
702 702 c, g dbSNP:774254522
706 706 c, t dbSNP:202185692
707 707 c, t dbSNP:771740493
711 711 a, g dbSNP:772805781
713 713 a, g dbSNP:760380062
722 722 c, t dbSNP:141157946
723 723 a, g dbSNP:753369803
724 724 a, g dbSNP:763411542
728 728 a, g dbSNP:764627661
737 737 a, c dbSNP:751901379
740 740 c, t dbSNP:766510092
741 741 a, g dbSNP:368377216
746 746 c, t dbSNP:372432466
754 754 c, t dbSNP:267600349
755 755 c, t dbSNP:375363208
757 757 a, g dbSNP:756377536
759 759 a, t dbSNP:45455404
782 782 g, t dbSNP:75246520
786 786 a, g dbSNP:755173906
789 789 a, g dbSNP:779138447
791 791 a, g dbSNP:369690547
792 792 a, g dbSNP:758383396
807 807 c, t dbSNP:777393341
808 808 a, g, t dbSNP:373585898
812 812 c, g dbSNP:1442
821 821 c, g, t dbSNP:745381374
822 822 a, g dbSNP:533509858
828 828 c, t dbSNP:762183440
835 835 a, c dbSNP:551894628
839 839 c, t dbSNP:369362360
840 840 a, g dbSNP:761157035
847 847 g, t dbSNP:766702824
851 851 c, t dbSNP:183236719
852 852 c, t dbSNP:755263822
854 854 c, t dbSNP:527506142
857 857 c, t dbSNP:377332036
871 871 c, t dbSNP:752853798
877 877 c, t dbSNP:758239106
880 880 c, t dbSNP:534794507
883 883 a, g dbSNP:751300973
884 884 c, t dbSNP:113538354
886 886 a, g dbSNP:780973591
893 893 a, g dbSNP:745469804
900 900 a, c dbSNP:370262564
901 901 c, t dbSNP:376340498
902 902 g, t dbSNP:748787000
906 906 a, g dbSNP:11543192
908 908 c, t dbSNP:772472646
909 909 a, g dbSNP:773703730
914 914 c, t dbSNP:761260418
930 930 c, t dbSNP:771481298
931 931 a, g dbSNP:377709778
933 933 g, t dbSNP:769919748
943 943 c, g dbSNP:775713146
947 947 a, c dbSNP:763079224
961 961 c, t dbSNP:757122798
962 962 a, c, g dbSNP:200535601
965 965 a, g dbSNP:761773998
966 966 a, c, t dbSNP:199852470
969 969 a, g dbSNP:755874694
972 972 a, g dbSNP:766085944
973 973 g, t dbSNP:753586534
974 974 c, t dbSNP:17849888
976 976 a, c, g dbSNP:201177738
977 977 c, t dbSNP:34334509
978 978 a, g dbSNP:184978714
988 988 c, t dbSNP:757860567
989 989 a, g dbSNP:781740702
990 990 c, g dbSNP:373990552
996 996 a, g dbSNP:770258308
999 999 c, t dbSNP:775701499
1000 1000 c, t dbSNP:746118957
1003 1003 a, c dbSNP:367862160
1013 1013 a, c dbSNP:189359867
1016 1016 c, t dbSNP:774441421
1017 1017 a, g dbSNP:375533446
1022 1022 a, g dbSNP:767449689
1023 1023 a, c dbSNP:773202924
1027 1027 c, g dbSNP:760518347
1036 1036 a, c dbSNP:766246728
1042 1042 a, g dbSNP:753546277
1045 1045 a, g dbSNP:754690721
1049 1049 c, g dbSNP:764932921
1054 1054 a, g dbSNP:752266395
1055 1055 c, t dbSNP:556797846
1056 1056 a, g dbSNP:202239395
1062 1062 a, g dbSNP:578206753
1076 1076 c, t dbSNP:754237763
1084 1084 a, g dbSNP:746482926
1107 1107 a, g dbSNP:779237998
1108 1108 -, g dbSNP:754006381
1112 1112 g, t dbSNP:748420018
1113 1113 a, g dbSNP:199686929
1124 1124 c, t dbSNP:373071121
1125 1125 a, g, t dbSNP:188428210
1129 1129 a, c, t dbSNP:201210696
1130 1130 a, g dbSNP:533421485
1137 1137 a, g, t dbSNP:775399687
1139 1139 c, t dbSNP:763795735
1142 1142 a, g dbSNP:1054124
1148 1148 a, c dbSNP:761165775
1159 1159 c, t dbSNP:767052038
1160 1160 a, g dbSNP:754364652
1161 1161 a, g dbSNP:201709971
1170 1170 g, t dbSNP:779292699
1181 1181 c, t dbSNP:753020018
1182 1182 a, g dbSNP:758642455
1186 1186 a, g dbSNP:756998485
1188 1188 a, g dbSNP:35920018
1189 1189 a, t dbSNP:770981462
1203 1203 a, g, t dbSNP:370797081
1210 1210 c, t dbSNP:769820632
1211 1211 a, g dbSNP:374082690
1222 1222 a, g dbSNP:201158209
1237 1237 a, c dbSNP:181628475
1239 1239 a, t dbSNP:768431533
1241 1241 c, t dbSNP:773946222
1244 1244 c, t dbSNP:199645034
1245 1245 a, g dbSNP:781002692
1247 1247 a, g dbSNP:766987280
1248 1248 a, g dbSNP:772749342
1250 1250 a, g dbSNP:760069077
1253 1253 c, t dbSNP:765684035
1254 1254 c, t dbSNP:753074962
1263 1263 a, g dbSNP:758695308
1269 1269 c, t dbSNP:11543191
1281 1281 a, g dbSNP:764514063
1285 1285 a, c, t dbSNP:751785771
1292 1292 a, g, t dbSNP:557545677
1300 1300 c, t dbSNP:749290056
1312 1312 c, t dbSNP:201060478
1313 1313 a, g dbSNP:778606022
1317 1317 a, t dbSNP:747929238
1320 1320 c, g dbSNP:771637478
1327 1327 a, c dbSNP:779534878
1328 1328 c, t dbSNP:369100201
1336 1336 c, t dbSNP:534142584
1339 1339 a, t dbSNP:770486230
1340 1340 c, t dbSNP:776095223
1341 1341 a, c dbSNP:763406980
1345 1345 c, t dbSNP:769163905
1349 1349 a, g dbSNP:774597247
1355 1355 c, t dbSNP:555953015
1356 1356 a, g, t dbSNP:767772054
1361 1361 c, t dbSNP:538237584
1362 1362 a, g dbSNP:750693052
1363 1363 g, t dbSNP:190842339
1368 1368 c, t dbSNP:754896151
1374 1374 c, t dbSNP:778852129
1376 1376 c, t dbSNP:752440306
1382 1382 g, t dbSNP:758278795
1386 1386 c, g, t dbSNP:777531295
1387 1387 a, g dbSNP:770539339
1400 1400 a, c, g, t dbSNP:780708123
1404 1404 c, t dbSNP:774850509
1415 1415 a, t dbSNP:762216519
1433 1433 a, c dbSNP:758987486
1441 1441 c, t dbSNP:545095042
1444 1444 a, t dbSNP:747515492
1449 1449 c, t dbSNP:771481430
1452 1452 a, g dbSNP:554088498
1464 1464 c, t dbSNP:746140236
1467 1467 a, c, t dbSNP:200298786
1468 1468 a, g dbSNP:762959190
1469 1469 a, g dbSNP:764020370
1473 1473 c, t dbSNP:148555720
1476 1476 a, g dbSNP:761720461
1489 1489 a, g dbSNP:771878326
1490 1490 g, t dbSNP:370832393
1496 1496 c, t dbSNP:201780948
1513 1513 a, g dbSNP:373018643
1514 1514 c, t dbSNP:542701103
1515 1515 a, g dbSNP:574159504
1527 1527 a, g dbSNP:755816737
1531 1531 c, g dbSNP:376040755
1534 1534 c, t dbSNP:753393470
1538 1538 c, t dbSNP:190191005
1539 1539 a, g dbSNP:778554252
1546 1546 a, c dbSNP:199862235
1549 1549 -, tg dbSNP:779200227
1564 1564 a, g dbSNP:757805572
1565 1565 c, t dbSNP:781643226
1566 1566 c, t dbSNP:759370852
1567 1567 a, g dbSNP:376761086
1574 1574 a, c dbSNP:778990116
1575 1575 c, g dbSNP:748172304
1577 1577 c, t dbSNP:1133170
1579 1579 g, t dbSNP:773091203
1583 1583 c, t dbSNP:760650058
1585 1585 a, g dbSNP:770681287
1598 1598 c, t dbSNP:776535345
1599 1599 a, g dbSNP:759291013
1600 1600 a, c, t dbSNP:192398905
1601 1601 a, g, t dbSNP:145354485
1603 1603 c, g dbSNP:750947320
1604 1604 c, t dbSNP:756618938
1607 1607 c, t dbSNP:766764647
1608 1608 a, g dbSNP:754155367
1611 1611 a, g dbSNP:755211334
1615 1615 a, c, g, t dbSNP:539008520
1616 1616 c, g dbSNP:777888998
1617 1617 a, g dbSNP:746961065
1620 1620 a, t dbSNP:770861252
1621 1621 a, g dbSNP:746868533
1625 1625 c, t dbSNP:372556093
1626 1626 a, g dbSNP:548047307
1628 1628 c, g dbSNP:769574207
1629 1629 a, g dbSNP:775346438
1637 1637 a, c dbSNP:376760680
1639 1639 c, t dbSNP:763560027
1645 1645 a, g dbSNP:773875117
1646 1646 a, c dbSNP:761112429
1647 1647 c, g, t dbSNP:10057190
1648 1648 a, g dbSNP:114295767
1652 1652 a, g dbSNP:376133587
1656 1656 -, c dbSNP:771515402
1657 1657 c, t dbSNP:765573708
1658 1658 a, c dbSNP:752912680
1659 1659 c, t dbSNP:554511298
1660 1660 c, g dbSNP:777744532
1662 1662 a, c, g, t dbSNP:121909212
1665 1665 a, g dbSNP:188677757
1667 1667 a, g dbSNP:769765518
1669 1669 g, t dbSNP:775399769
1670 1670 g, t dbSNP:556133731
1674 1674 a, g dbSNP:201775031
1677 1677 a, g dbSNP:773750127
1687 1687 g, t dbSNP:121909216
1691 1691 a, g dbSNP:761324414
1695 1695 a, g dbSNP:370523274
1701 1701 a, c, g, t dbSNP:200065806
1702 1702 a, g dbSNP:73296968
1710 1710 a, c dbSNP:769946729
1713 1713 c, t dbSNP:763310312
1727 1727 c, t dbSNP:764361610
1744 1744 c, t dbSNP:530953796
1745 1745 a, g dbSNP:552261238
1747 1747 a, g dbSNP:767742299
1752 1752 c, g dbSNP:570927940
1758 1758 a, c dbSNP:756136153
1759 1759 a, g, t dbSNP:371923032
1780 1780 c, t dbSNP:121909214
1781 1781 c, t dbSNP:4669
1782 1782 a, g dbSNP:778550933
1783 1783 c, t dbSNP:747839006
1791 1791 a, g dbSNP:771674035
1792 1792 a, g dbSNP:777288957
1794 1794 a, g dbSNP:746455784
1798 1798 a, c dbSNP:267607109
1799 1799 c, t dbSNP:770204995
1803 1803 c, t dbSNP:367944058
1804 1804 a, g dbSNP:138125037
1806 1806 a, g dbSNP:202066916
1813 1813 a, c dbSNP:267607110
1816 1816 a, c dbSNP:769108952
1818 1818 a, g dbSNP:774822557
1824 1824 c, t dbSNP:121909208
1825 1825 a, g dbSNP:121909209
1829 1829 a, c dbSNP:762155321
1837 1837 g, t dbSNP:200219644
1838 1838 c, g dbSNP:554888573
1840 1840 g, t dbSNP:773630915
1845 1845 a, g dbSNP:760789364
1853 1853 a, g dbSNP:766520605
1874 1874 c, t dbSNP:771319985
1877 1877 c, t dbSNP:759542534
1879 1879 c, t dbSNP:779132788
1882 1882 a, g dbSNP:765029656
1901 1901 c, t dbSNP:752492343
1902 1902 a, g dbSNP:200887459
1905 1905 a, g dbSNP:763862790
1907 1907 c, t dbSNP:751257072
1910 1910 c, t dbSNP:35909506
1911 1911 a, g, t dbSNP:540916345
1912 1912 c, g dbSNP:555842830
1913 1913 a, g dbSNP:755520624
1916 1916 a, c dbSNP:779632250
1917 1917 a, c dbSNP:748653708
1921 1921 c, t dbSNP:772614275
1923 1923 c, t dbSNP:563306013
1924 1924 a, g dbSNP:377713090
1954 1954 a, t dbSNP:199579539
1959 1959 a, t dbSNP:771013982
1961 1961 c, t dbSNP:776788877
1963 1963 g, t dbSNP:759465529
1964 1964 a, g dbSNP:35151677
1970 1970 c, t dbSNP:746086626
1972 1972 a, g dbSNP:769907715
1977 1977 c, g dbSNP:775512591
1983 1983 a, g dbSNP:762908437
1987 1987 a, g dbSNP:768531616
1992 1992 a, g dbSNP:774207585
2003 2003 c, g, t dbSNP:761445898
2004 2004 a, g dbSNP:750093806
2012 2012 c, t dbSNP:545033194
2013 2013 a, c, g dbSNP:760372743
2029 2029 a, g dbSNP:121909215
2030 2030 c, t dbSNP:753353112
2031 2031 a, g dbSNP:200201691
2033 2033 a, g dbSNP:778360033
2039 2039 c, t dbSNP:45563337
2047 2047 c, t dbSNP:752099635
2051 2051 c, t dbSNP:757617851
2052 2052 g, t dbSNP:781594177
2068 2068 c, t dbSNP:749505741
2073 2073 a, g dbSNP:755101277
2077 2077 c, t dbSNP:779021511
2082 2082 a, g dbSNP:748068717
2086 2086 a, g dbSNP:772001755
2088 2088 a, g dbSNP:772899840
2091 2091 a, g dbSNP:746736734
2093 2093 a, t dbSNP:770847660
2099 2099 c, t dbSNP:530050309
2102 2102 a, c dbSNP:759237930
2107 2107 c, g, t dbSNP:377519138
2110 2110 c, t dbSNP:188333040
2111 2111 a, g dbSNP:570146042
2115 2115 a, c, g dbSNP:143831210
2122 2122 g, t dbSNP:766709594
2124 2124 a, c dbSNP:777996516
2130 2130 a, g dbSNP:754100343
2136 2136 g, t dbSNP:180713598
2138 2138 a, g dbSNP:79829394
2142 2142 -, t dbSNP:34975207
2143 2143 a, c dbSNP:778881982
2153 2153 c, t dbSNP:199781494
2157 2157 a, c dbSNP:761193316
2158 2158 a, g dbSNP:771371313
2159 2159 c, g dbSNP:121909217
2162 2162 c, t dbSNP:760016493
2166 2166 c, t dbSNP:201554996
2173 2173 c, g dbSNP:775675020
2181 2181 c, t dbSNP:763254285
2185 2185 -, aa dbSNP:761547065
2196 2196 c, g dbSNP:200927007
2197 2197 a, c dbSNP:774575626
2201 2201 c, g dbSNP:762051168
2206 2206 a, c dbSNP:767689311
2209 2209 -, t dbSNP:767332806
2210 2210 g, t dbSNP:750422411
2220 2220 a, g dbSNP:755966730
2222 2222 a, g dbSNP:766220255
2225 2225 a, g dbSNP:753519514
2231 2231 g, t dbSNP:754630126
2237 2237 c, t dbSNP:778607521
2242 2242 c, t dbSNP:370910755
2243 2243 a, g dbSNP:373032581
2243 2243 -, g dbSNP:750260007
2248 2248 c, g dbSNP:757955922
2253 2253 c, t dbSNP:376033284
2254 2254 a, g, t dbSNP:746415976
2258 2258 a, g dbSNP:370309697
2262 2262 a, c dbSNP:749594991
2282 2282 a, c dbSNP:745473975
2283 2283 -, tgtt dbSNP:368290568
2285 2285 -, tttg dbSNP:376325382
2285 2285 c, t dbSNP:373984033
2324 2324 c, t dbSNP:548337176
2332 2332 a, g dbSNP:142145618
2364 2364 g, t dbSNP:377202155
2372 2372 a, t dbSNP:530791523
2386 2386 a, g dbSNP:551804653
2432 2432 a, c dbSNP:146047755
2480 2480 a, c, g, t dbSNP:17169782
2484 2484 a, c dbSNP:1804507
2508 2508 c, t dbSNP:552665555
2552 2552 a, c dbSNP:568122995
2556 2556 a, g dbSNP:535677136
2566 2566 c, t dbSNP:774179960
2608 2608 a, c dbSNP:558406262
2669 2669 a, g dbSNP:575891622
2671 2671 a, g dbSNP:7854
2685 2685 c, t dbSNP:558209125
2686 2686 a, g dbSNP:573094725
2698 2698 c, t dbSNP:14813
2734 2734 a, t dbSNP:764465838
2750 2750 g, t dbSNP:4572
2760 2760 a, t dbSNP:79114801

Target ORF information:

RefSeq Version NM_000358
Organism Homo sapiens (human)
Definition Homo sapiens transforming growth factor, beta-induced, 68kDa (TGFBI), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_000358

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
ATGGCGCTCT TCGTGCGGCT GCTGGCTCTC GCCCTGGCTC TGGCCCTGGG CCCCGCCGCG 
ACCCTGGCGG GTCCCGCCAA GTCGCCCTAC CAGCTGGTGC TGCAGCACAG CAGGCTCCGG
GGCCGCCAGC ACGGCCCCAA CGTGTGTGCT GTGCAGAAGG TTATTGGCAC TAATAGGAAG
TACTTCACCA ACTGCAAGCA GTGGTACCAA AGGAAAATCT GTGGCAAATC AACAGTCATC
AGCTACGAGT GCTGTCCTGG ATATGAAAAG GTCCCTGGGG AGAAGGGCTG TCCAGCAGCC
CTACCACTCT CAAACCTTTA CGAGACCCTG GGAGTCGTTG GATCCACCAC CACTCAGCTG
TACACGGACC GCACGGAGAA GCTGAGGCCT GAGATGGAGG GGCCCGGCAG CTTCACCATC
TTCGCCCCTA GCAACGAGGC CTGGGCCTCC TTGCCAGCTG AAGTGCTGGA CTCCCTGGTC
AGCAATGTCA ACATTGAGCT GCTCAATGCC CTCCGCTACC ATATGGTGGG CAGGCGAGTC
CTGACTGATG AGCTGAAACA CGGCATGACC CTCACCTCTA TGTACCAGAA TTCCAACATC
CAGATCCACC ACTATCCTAA TGGGATTGTA ACTGTGAACT GTGCCCGGCT GCTGAAAGCC
GACCACCATG CAACCAACGG GGTGGTGCAC CTCATCGATA AGGTCATCTC CACCATCACC
AACAACATCC AGCAGATCAT TGAGATCGAG GACACCTTTG AGACCCTTCG GGCTGCTGTG
GCTGCATCAG GGCTCAACAC GATGCTTGAA GGTAACGGCC AGTACACGCT TTTGGCCCCG
ACCAATGAGG CCTTCGAGAA GATCCCTAGT GAGACTTTGA ACCGTATCCT GGGCGACCCA
GAAGCCCTGA GAGACCTGCT GAACAACCAC ATCTTGAAGT CAGCTATGTG TGCTGAAGCC
ATCGTTGCGG GGCTGTCTGT AGAGACCCTG GAGGGCACGA CACTGGAGGT GGGCTGCAGC
GGGGACATGC TCACTATCAA CGGGAAGGCG ATCATCTCCA ATAAAGACAT CCTAGCCACC
AACGGGGTGA TCCACTACAT TGATGAGCTA CTCATCCCAG ACTCAGCCAA GACACTATTT
GAATTGGCTG CAGAGTCTGA TGTGTCCACA GCCATTGACC TTTTCAGACA AGCCGGCCTC
GGCAATCATC TCTCTGGAAG TGAGCGGTTG ACCCTCCTGG CTCCCCTGAA TTCTGTATTC
AAAGATGGAA CCCCTCCAAT TGATGCCCAT ACAAGGAATT TGCTTCGGAA CCACATAATT
AAAGACCAGC TGGCCTCTAA GTATCTGTAC CATGGACAGA CCCTGGAAAC TCTGGGCGGC
AAAAAACTGA GAGTTTTTGT TTATCGTAAT AGCCTCTGCA TTGAGAACAG CTGCATCGCG
GCCCACGACA AGAGGGGGAG GTACGGGACC CTGTTCACGA TGGACCGGGT GCTGACCCCC
CCAATGGGGA CTGTCATGGA TGTCCTGAAG GGAGACAATC GCTTTAGCAT GCTGGTAGCT
GCCATCCAGT CTGCAGGACT GACGGAGACC CTCAACCGGG AAGGAGTCTA CACAGTCTTT
GCTCCCACAA ATGAAGCCTT CCGAGCCCTG CCACCAAGAG AACGGAGCAG ACTCTTGGGA
GATGCCAAGG AACTTGCCAA CATCCTGAAA TACCACATTG GTGATGAAAT CCTGGTTAGC
GGAGGCATCG GGGCCCTGGT GCGGCTAAAG TCTCTCCAAG GTGACAAGCT GGAAGTCAGC
TTGAAAAACA ATGTGGTGAG TGTCAACAAG GAGCCTGTTG CCGAGCCTGA CATCATGGCC
ACAAATGGCG TGGTCCATGT CATCACCAAT GTTCTGCAGC CTCCAGCCAA CAGACCTCAG
GAAAGAGGGG ATGAACTTGC AGACTCTGCG CTTGAGATCT TCAAACAAGC ATCAGCGTTT
TCCAGGGCTT CCCAGAGGTC TGTGCGACTA GCCCCTGTCT ATCAAAAGTT ATTAGAGAGG
ATGAAGCATT AG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.