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TGFBR1 transforming growth factor, beta receptor 1 [Homo sapiens (human)]

Gene Symbol TGFBR1
Entrez Gene ID 7046
Full Name transforming growth factor, beta receptor 1
Synonyms AAT5, ACVRLK4, ALK-5, ALK5, ESS1, LDS1, LDS1A, LDS2A, MSSE, SKR4, TGFR-1, tbetaR-I
General protein information
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

9

9q22

Summary The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]. lac of sum
Disorder MIM:

190181

Disorder Html: Loeys-Dietz syndrome, type 1A, 609192 (3); Loeys-Dietz syndrome,





The following TGFBR1 gene sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TGFBR1 gene which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu60974 XM_011518948 PREDICTED: Homo sapiens transforming growth factor, beta receptor 1 (TGFBR1), transcript variant X2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $319
OHu60975 XM_011518949 PREDICTED: Homo sapiens transforming growth factor, beta receptor 1 (TGFBR1), transcript variant X3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $319
OHu60976 XM_011518950 PREDICTED: Homo sapiens transforming growth factor, beta receptor 1 (TGFBR1), transcript variant X4, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 5-7 $319
OHu16616 NM_001130916 Homo sapiens transforming growth factor, beta receptor 1 (TGFBR1), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector TBD $379
OHu17991 NM_004612 Homo sapiens transforming growth factor, beta receptor 1 (TGFBR1), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector TBD $429
OHu43465 NM_001306210 Homo sapiens transforming growth factor, beta receptor 1 (TGFBR1), transcript variant 3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector TBD $439

*Business Day
**You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.


CloneID OHu60974
Accession Version XM_011518948.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1317bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector Document: User manual_GenEZ ORF Clone Products.pdf (pdf)
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags Document: MSDS_GenEZ ORF Clone Products.pdf (pdf)
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product TGF-beta receptor type-1 isoform X2
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_008470.20) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
ATGTGTATAG CTGAAATTGA CTTAATTCCT CGAGATAGGC CGTTTGTATG TGCACCCTCT 
TCAAAAACTG GGTCTGTGAC TACAACATAT TGCTGCAATC AGGACCATTG CAATAAAATA
GAACTTCCAA CTACTGGCCC TTTTTCAGTA AAGTCATCAC CTGGCCTTGG TCCTGTGGAA
CTGGCAGCTG TCATTGCTGG ACCAGTGTGC TTCGTCTGCA TCTCACTCAT GTTGATGGTC
TATATCTGCC ACAACCGCAC TGTCATTCAC CATCGAGTGC CAAATGAAGA GGACCCTTCA
TTAGATCGCC CTTTTATTTC AGAGGGTACT ACGTTGAAAG ACTTAATTTA TGATATGACA
ACGTCAGGTT CTGGCTCAGG TTTACCATTG CTTGTTCAGA GAACAATTGC GAGAACTATT
GTGTTACAAG AAAGCATTGG CAAAGGTCGA TTTGGAGAAG TTTGGAGAGG AAAGTGGCGG
GGAGAAGAAG TTGCTGTTAA GATATTCTCC TCTAGAGAAG AACGTTCGTG GTTCCGTGAG
GCAGAGATTT ATCAAACTGT AATGTTACGT CATGAAAACA TCCTGGGATT TATAGCAGCA
GACAATAAAG ACAATGGTAC TTGGACTCAG CTCTGGTTGG TGTCAGATTA TCATGAGCAT
GGATCCCTTT TTGATTACTT AAACAGATAC ACAGTTACTG TGGAAGGAAT GATAAAACTT
GCTCTGTCCA CGGCGAGCGG TCTTGCCCAT CTTCACATGG AGATTGTTGG TACCCAAGGA
AAGCCAGCCA TTGCTCATAG AGATTTGAAA TCAAAGAATA TCTTGGTAAA GAAGAATGGA
ACTTGCTGTA TTGCAGACTT AGGACTGGCA GTAAGACATG ATTCAGCCAC AGATACCATT
GATATTGCTC CAAACCACAG AGTGGGAACA AAAAGGTACA TGGCCCCTGA AGTTCTCGAT
GATTCCATAA ATATGAAACA TTTTGAATCC TTCAAACGTG CTGACATCTA TGCAATGGGC
TTAGTATTCT GGGAAATTGC TCGACGATGT TCCATTGGTG GAATTCATGA AGATTACCAA
CTGCCTTATT ATGATCTTGT ACCTTCTGAC CCATCAGTTG AAGAAATGAG AAAAGTTGTT
TGTGAACAGA AGTTAAGGCC AAATATCCCA AACAGATGGC AGAGCTGTGA AGCCTTGAGA
GTAATGGCTA AAATTATGAG AGAATGTTGG TATGCCAATG GAGCAGCTAG GCTTACAGCA
TTGCGGATTA AGAAAACATT ATCGCAACTC AGTCAACAGG AAGGCATCAA AATGTAA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqXP_011517250.1
CDS240..1556
Misc Feature(1)240..374(+)
Misc Feature(2)567..653(+)
Misc Feature(3)657..1514(+)
Misc Feature(4)669..1532(+)
Misc Feature(5)675..1175(+)
Misc Feature(6)675..1097(+)
Misc Feature(7)687..1175(+)
Misc Feature(8)768..845(+)
Misc Feature(9)1092..1175(+)
Translation
Position Chain Variation Link
27 27 c, g, t dbSNP:771020516
52 52 a, g dbSNP:148567056
72 72 c, t dbSNP:11568753
97 97 a, g dbSNP:542480483
107 107 c, g dbSNP:755527253
108 108 a, g dbSNP:562609002
114 114 -, a dbSNP:575497750
131 131 a, g, t dbSNP:779055286
136 136 a, g dbSNP:772361141
145 145 a, g dbSNP:750150798
152 152 c, t dbSNP:201267786
153 153 a, t dbSNP:543397817
157 157 -, c dbSNP:772089863
166 166 a, g dbSNP:387906696
167 167 c, t dbSNP:369226180
173 173 a, t dbSNP:776285294
186 186 c, g dbSNP:587776865
188 188 a, g dbSNP:761368421
200 200 c, t dbSNP:199534451
219 219 a, g dbSNP:200779997
220 220 a, g dbSNP:765004526
224 224 a, g dbSNP:112051451
227 227 a, t dbSNP:762638283
231 231 c, t dbSNP:766157497
235 235 a, g dbSNP:727503469
239 239 c, t dbSNP:145033378
246 246 a, t dbSNP:111513627
254 254 a, c dbSNP:201910738
257 257 c, t dbSNP:200543076
261 261 g, t dbSNP:753933625
280 280 c, t dbSNP:757374917
281 281 a, g dbSNP:200091200
285 285 g, t dbSNP:746141820
299 299 g, t dbSNP:772324783
302 302 -, a dbSNP:147107882
324 324 a, t dbSNP:780295872
326 326 a, c dbSNP:747332492
329 329 c, t dbSNP:550395617
336 336 a, g dbSNP:769320006
337 337 a, g dbSNP:200860457
347 347 c, t dbSNP:201771506
350 350 c, t dbSNP:149417020
362 362 a, g dbSNP:769471584
366 366 c, g dbSNP:199904970
369 369 a, g dbSNP:762573778
374 374 a, g, t dbSNP:371415976
377 377 a, c dbSNP:764024903
380 380 c, t dbSNP:750500147
384 384 g, t dbSNP:758455106
389 389 a, g dbSNP:766347880
397 397 c, t dbSNP:370568025
401 401 a, t dbSNP:755249354
402 402 a, g dbSNP:781729436
413 413 g, t dbSNP:773635581
414 414 a, g dbSNP:373391549
420 420 c, g dbSNP:756586874
426 426 c, g dbSNP:778289813
431 431 c, g dbSNP:749733473
436 436 c, g dbSNP:770511883
444 444 a, g dbSNP:730880222
452 452 c, t dbSNP:773845018
453 453 a, g dbSNP:745576967
459 459 a, g dbSNP:148176750
465 465 c, t dbSNP:749651186
478 478 g, t dbSNP:775267361
483 483 a, g dbSNP:760422619
484 484 c, t dbSNP:75857126
490 490 a, g dbSNP:768500160
495 495 c, t dbSNP:776680716
496 496 a, g dbSNP:539413187
501 501 a, g dbSNP:56014374
507 507 c, t dbSNP:751679796
514 514 c, g dbSNP:147146713
522 522 a, c dbSNP:113982335
523 523 a, g dbSNP:767785290
539 539 a, g dbSNP:753147276
543 543 c, g dbSNP:756547201
547 547 a, g dbSNP:777965779
550 550 c, g dbSNP:756643977
551 551 c, t dbSNP:754431973
560 560 a, g dbSNP:140245968
565 565 g, t dbSNP:121918713
567 567 a, t dbSNP:201137894
571 571 c, t dbSNP:745324433
572 572 a, g dbSNP:190878719
576 576 a, g dbSNP:779641991
601 601 a, c, t dbSNP:144313652
602 602 a, g, t dbSNP:538382054
612 612 c, g dbSNP:769785561
616 616 c, t dbSNP:774583379
626 626 a, t dbSNP:200679996
640 640 a, g dbSNP:397517032
643 643 c, t dbSNP:121918712
645 645 a, g dbSNP:781042616
650 650 a, g dbSNP:201497553
657 657 a, g dbSNP:200018073
677 677 a, t dbSNP:769871453
684 684 g, t dbSNP:727503470
716 716 a, g dbSNP:201021249
722 722 a, g dbSNP:201444476
724 724 a, g dbSNP:772339721
746 746 c, t dbSNP:202156059
762 762 c, t dbSNP:775429965
764 764 c, t dbSNP:200078591
766 766 c, t dbSNP:111854391
767 767 a, g dbSNP:201112150
785 785 a, g dbSNP:764165477
797 797 c, t dbSNP:202189494
804 804 c, t dbSNP:777077652
812 812 c, t dbSNP:762125867
823 823 a, t dbSNP:397517033
839 839 a, c dbSNP:200158200
843 843 a, g dbSNP:727503471
853 853 a, g dbSNP:201475375
854 854 c, t dbSNP:147388628
857 857 c, t dbSNP:200511345
879 879 c, g dbSNP:112300506
888 888 c, t dbSNP:755827803
905 905 c, t dbSNP:371269876
906 906 c, t dbSNP:201605956
915 915 c, t dbSNP:191136014
916 916 a, g dbSNP:35974499
922 922 a, g dbSNP:199759998
927 927 a, t dbSNP:200560562
932 932 a, g dbSNP:201943631
933 933 a, g dbSNP:757284158
936 936 a, g dbSNP:764452904
939 939 a, g dbSNP:199822546
941 941 a, g dbSNP:369881419
960 960 c, g, t dbSNP:768667498
962 962 c, t dbSNP:748434255
970 970 c, t dbSNP:200518416
971 971 a, g dbSNP:201323409
973 973 c, t dbSNP:202010361
974 974 a, g dbSNP:139090459
977 977 c, t dbSNP:200912890
978 978 a, g dbSNP:760079636
989 989 c, t dbSNP:767005593
996 996 a, c dbSNP:752190665
997 997 g, t dbSNP:121918710
1002 1002 a, c dbSNP:760419678
1037 1037 c, t dbSNP:199770942
1038 1038 -, agagat dbSNP:727504383
1052 1052 a, g dbSNP:761512764
1053 1053 a, g dbSNP:113911127
1076 1076 c, t dbSNP:192662552
1084 1084 a, c, g dbSNP:113786548
1109 1109 a, c, g dbSNP:758280185
1113 1113 a, g dbSNP:779100123
1135 1135 c, g dbSNP:201050937
1154 1154 c, t dbSNP:368402450
1163 1163 a, g dbSNP:777805295
1169 1169 a, c dbSNP:7861780
1182 1182 g, t dbSNP:746666082
1183 1183 c, g dbSNP:746047431
1185 1185 c, t dbSNP:760555508
1196 1196 c, t dbSNP:115324990
1205 1205 c, t dbSNP:747584981
1211 1211 c, t dbSNP:769218243
1213 1213 c, t dbSNP:199574997
1230 1230 g, t dbSNP:747644508
1237 1237 a, g dbSNP:200657153
1243 1243 a, g dbSNP:121918711
1247 1247 c, t dbSNP:200358981
1249 1249 a, g dbSNP:762486367
1252 1252 c, g, t dbSNP:557200755
1254 1254 a, g dbSNP:143435050
1260 1260 a, c, t dbSNP:200062984
1262 1262 a, g dbSNP:757399188
1263 1263 c, g dbSNP:146549837
1276 1276 c, t dbSNP:200986584
1281 1281 c, t dbSNP:200595614
1284 1284 c, t dbSNP:387906697
1293 1293 a, g dbSNP:764050602
1307 1307 a, t dbSNP:781386406
1319 1319 a, g dbSNP:753301297
1321 1321 g, t dbSNP:756570466
1322 1322 g, t dbSNP:368928967
1328 1328 c, t dbSNP:201163170
1329 1329 c, t dbSNP:201745016
1358 1358 c, t dbSNP:770604680
1368 1368 a, g dbSNP:778579239
1371 1371 a, g dbSNP:745499424
1388 1388 a, g dbSNP:771962930
1397 1397 a, g dbSNP:775143255
1399 1399 -, c dbSNP:111820381
1402 1402 a, c dbSNP:760666606
1422 1422 a, g dbSNP:768418563
1431 1431 g, t dbSNP:776749573
1432 1432 a, c dbSNP:748073284
1438 1438 a, g dbSNP:556555554
1443 1443 a, g dbSNP:199926741
1453 1453 c, t dbSNP:774565396
1464 1464 a, t dbSNP:759805984
1469 1469 g, t dbSNP:767589799
1477 1477 a, g, t dbSNP:141259922
1479 1479 a, g dbSNP:377194685
1488 1488 a, g dbSNP:730880223
1500 1500 c, t dbSNP:111818778
1503 1503 c, t dbSNP:111426349
1504 1504 a, c, g dbSNP:113605875
1523 1523 a, g dbSNP:144985585
1531 1531 a, g dbSNP:764733540
1533 1533 c, g dbSNP:749879202
1541 1541 a, g dbSNP:200055681
1561 1561 a, g dbSNP:201254457
1563 1563 a, g dbSNP:779531038
1576 1576 c, t dbSNP:369611795
1578 1578 c, g dbSNP:754777682
1581 1581 c, t dbSNP:202041245
1582 1582 g, t dbSNP:781117226
1582 1582 -, t dbSNP:746953792
1587 1587 c, t dbSNP:201753435
1593 1593 c, g dbSNP:769785618
1602 1602 c, t dbSNP:192327847
1608 1608 a, t dbSNP:745898677
1612 1612 a, g dbSNP:994
1625 1625 a, g dbSNP:868
1638 1638 a, t dbSNP:200966435
1656 1656 g, t dbSNP:201855724
1670 1670 c, t dbSNP:200434439
1675 1675 g, t dbSNP:184489732
1676 1676 c, t dbSNP:201350756
1688 1688 a, g dbSNP:767616657
1702 1702 -, c dbSNP:35702937
1743 1743 c, t dbSNP:202238690
1752 1752 c, t dbSNP:200533591
1761 1761 c, t dbSNP:201419046
1762 1762 a, g dbSNP:199609928
1767 1767 a, t dbSNP:200495698
1783 1783 a, t dbSNP:760980107
1800 1800 a, g dbSNP:560210246
1808 1808 c, t dbSNP:201563225
1853 1853 c, t dbSNP:199683401
1867 1867 a, g dbSNP:200804500
1878 1878 a, c dbSNP:528867293
1894 1894 a, g dbSNP:201682869
1895 1895 g, t dbSNP:199861787
1901 1901 a, g dbSNP:200832519
1913 1913 a, t dbSNP:368380699
1914 1914 c, t dbSNP:764209146
1916 1916 a, g dbSNP:145692006
1927 1927 c, t dbSNP:200019371
1928 1928 c, t dbSNP:200786932
1931 1931 c, t dbSNP:201903995
1962 1962 a, t dbSNP:750730238
1972 1972 c, g dbSNP:200063976
1985 1985 c, g dbSNP:201260283
1997 1997 c, t dbSNP:202012098
2012 2012 g, t dbSNP:200245567
2026 2026 a, g dbSNP:201142879
2029 2029 -, t dbSNP:568494416
2029 2029 a, g dbSNP:202133538
2038 2038 g, t dbSNP:200294552
2041 2041 c, g dbSNP:531460959
2058 2058 c, t dbSNP:201269197
2064 2064 -, tctta dbSNP:777186940
2069 2069 a, t dbSNP:199521592
2076 2076 c, t dbSNP:200514984
2079 2079 a, g dbSNP:11568807
2094 2094 c, t dbSNP:199578935
2108 2108 a, g dbSNP:200511595
2111 2111 a, g dbSNP:201606447
2115 2115 a, g dbSNP:559337318
2118 2118 c, g dbSNP:199765042
2122 2122 c, t dbSNP:11568808
2130 2130 a, g dbSNP:201687617
2135 2135 c, g dbSNP:754640242
2147 2147 -, tt dbSNP:750491076
2185 2185 a, c dbSNP:199867951
2193 2193 a, g dbSNP:201205567
2268 2268 a, g dbSNP:780634517
2270 2270 a, g dbSNP:201984381
2284 2284 a, g dbSNP:199993828
2312 2312 c, t dbSNP:200926268
2334 2334 a, g dbSNP:202158467
2345 2345 a, g dbSNP:200428927
2352 2352 a, c dbSNP:201076760
2387 2387 a, c dbSNP:201996934
2399 2399 g, t dbSNP:200224469
2405 2405 c, t dbSNP:201615730
2433 2433 a, g dbSNP:199734350
2440 2440 a, g dbSNP:334348
2446 2446 a, g dbSNP:201052504
2448 2448 a, g dbSNP:199549381
2449 2449 a, g dbSNP:200679214
2455 2455 c, t dbSNP:36049024
2469 2469 c, t dbSNP:201990134
2477 2477 g, t dbSNP:34325659
2482 2482 c, t dbSNP:199584415
2505 2505 a, g dbSNP:189593120
2523 2523 c, g dbSNP:200755777
2529 2529 c, g dbSNP:756852117
2534 2534 a, g dbSNP:35870119
2560 2560 a, t dbSNP:35607843
2562 2562 c, t dbSNP:201910377
2590 2590 a, g dbSNP:200005909
2592 2592 g, t dbSNP:201098935
2602 2602 g, t dbSNP:201701125
2605 2605 c, t dbSNP:11568809
2619 2619 a, g dbSNP:201191454
2622 2622 a, g dbSNP:778564621
2633 2633 a, g dbSNP:539294464
2644 2644 c, t dbSNP:202224779
2648 2648 a, g dbSNP:559316578
2659 2659 c, g dbSNP:199978072
2667 2667 c, t dbSNP:201110333
2710 2710 c, t dbSNP:141078676
2727 2727 c, t dbSNP:10988732
2735 2735 a, g dbSNP:193056376
2738 2738 c, t dbSNP:200376574
2739 2739 a, g dbSNP:184564501
2762 2762 c, g dbSNP:201746454
2763 2763 a, g dbSNP:200186059
2788 2788 c, t dbSNP:201621825
2795 2795 c, t dbSNP:199740407
2796 2796 a, g dbSNP:200689459
2800 2800 a, g dbSNP:201519485
2815 2815 c, g, t dbSNP:150247576
2816 2816 a, g dbSNP:200765185
2824 2824 c, t dbSNP:541995278
2825 2825 c, g, t dbSNP:189032587
2826 2826 c, t dbSNP:774659140
2844 2844 g, t dbSNP:199956399
2849 2849 c, g, t dbSNP:200739404
2872 2872 c, g dbSNP:201894361
2876 2876 a, g dbSNP:138860379
2880 2880 c, t dbSNP:564868044
2888 2888 a, g dbSNP:200076723
2898 2898 a, g dbSNP:201116349
2899 2899 c, t dbSNP:11568810
2902 2902 a, g dbSNP:567642330
2920 2920 c, t dbSNP:530171542
2921 2921 g, t dbSNP:199891042
2925 2925 a, g dbSNP:200970226
2932 2932 c, g dbSNP:201863088
2934 2934 a, g dbSNP:200278937
2961 2961 c, t dbSNP:201453348
2966 2966 c, t dbSNP:201952413
2968 2968 c, t dbSNP:200562457
2984 2984 c, g dbSNP:11568811
3003 3003 a, t dbSNP:199588065
3007 3007 c, t dbSNP:200560836
3011 3011 c, t dbSNP:760928585
3012 3012 a, g dbSNP:769029753
3065 3065 g, t dbSNP:570039754
3071 3071 a, g dbSNP:11568812
3085 3085 a, g dbSNP:559280038
3097 3097 c, t dbSNP:199733000
3098 3098 g, t dbSNP:776540727
3123 3123 a, g dbSNP:200669525
3128 3128 a, g dbSNP:79410528
3130 3130 a, g dbSNP:199522012
3138 3138 c, t dbSNP:200943776
3159 3159 a, g dbSNP:201500025
3168 3168 c, t dbSNP:200036408
3170 3170 a, g dbSNP:200791684
3196 3196 a, g dbSNP:201604963
3215 3215 c, t dbSNP:200082162
3242 3242 -, ta dbSNP:780605360
3244 3244 c, t dbSNP:201101156
3253 3253 c, t dbSNP:181403208
3266 3266 a, g dbSNP:200197062
3304 3304 a, g dbSNP:201222590
3307 3307 c, t dbSNP:202128625
3308 3308 a, g dbSNP:200296344
3315 3315 a, c dbSNP:183812806
3328 3328 a, c dbSNP:201191009
3334 3334 a, g dbSNP:200566464
3354 3354 c, t dbSNP:138248864
3355 3355 a, g dbSNP:199580278
3360 3360 a, g dbSNP:200656974
3381 3381 a, g dbSNP:201607717
3424 3424 a, g dbSNP:199765790
3425 3425 c, g dbSNP:200570178
3434 3434 g, t dbSNP:201434094
3497 3497 a, t dbSNP:199811787
3516 3516 c, t dbSNP:201307737
3544 3544 g, t dbSNP:201829833
3561 3561 g, t dbSNP:144216869
3599 3599 a, g dbSNP:527618646
3626 3626 a, t dbSNP:540978964
3637 3637 -, gtt dbSNP:75796733
3637 3637 g, t dbSNP:200898127
3638 3638 g, t dbSNP:112113922
3642 3642 g, t dbSNP:148063684
3646 3646 a, g, t dbSNP:201152885
3648 3648 -, t dbSNP:376556150
3648 3648 g, t dbSNP:199545273
3649 3649 g, t dbSNP:202187266
3649 3649 -, t dbSNP:200529894
3650 3650 g, t dbSNP:200204084
3651 3651 g, t dbSNP:201780012
3652 3652 -, tg dbSNP:541820908
3652 3652 g, t dbSNP:200867114
3653 3653 -, g, gt dbSNP:61566226
3654 3654 g, t dbSNP:201738100
3655 3655 g, t dbSNP:199659996
3656 3656 g, t dbSNP:532530728
3659 3659 -, g dbSNP:36064078
3659 3659 g, t dbSNP:7871490
3662 3662 g, t dbSNP:201054018
3668 3668 -, ttt dbSNP:199589877
3668 3668 g, t dbSNP:60885995
3673 3673 g, t dbSNP:181680115
3702 3702 c, t dbSNP:200675329
3710 3710 a, g dbSNP:201153037
3735 3735 -, a dbSNP:373576679
3790 3790 a, g dbSNP:754588954
3802 3802 g, t dbSNP:552650250
3809 3809 c, t dbSNP:199645690
3818 3818 g, t dbSNP:200653031
3830 3830 a, g dbSNP:202068970
3949 3949 a, g dbSNP:77810552
3966 3966 c, t dbSNP:200722893
3967 3967 a, g dbSNP:11568813
3971 3971 g, t dbSNP:140497381
3982 3982 a, g dbSNP:185811148
4007 4007 g, t dbSNP:201140077
4029 4029 a, t dbSNP:202106034
4038 4038 -, gaaa dbSNP:747408434
4076 4076 c, t dbSNP:200032389
4077 4077 c, t dbSNP:200985953
4078 4078 a, g dbSNP:202239214
4092 4092 a, c dbSNP:200378819
4112 4112 a, t dbSNP:200553684
4129 4129 c, t dbSNP:537279747
4131 4131 a, g dbSNP:201156487
4144 4144 c, t dbSNP:201719827
4146 4146 a, c dbSNP:11544423
4174 4174 c, g dbSNP:200240411
4176 4176 a, g dbSNP:201765733
4183 4183 g, t dbSNP:147373120
4192 4192 a, t dbSNP:199685230
4194 4194 c, t dbSNP:555815837
4201 4201 a, c dbSNP:17724567
4202 4202 c, t dbSNP:201410594
4208 4208 a, g dbSNP:199515707
4229 4229 a, g dbSNP:749188476
4241 4241 g, t dbSNP:145043837
4250 4250 a, g dbSNP:201761492
4251 4251 a, g dbSNP:199959704
4252 4252 a, g dbSNP:200552727
4254 4254 a, g dbSNP:202073426
4259 4259 a, g dbSNP:76392135
4263 4263 c, t dbSNP:201264579
4288 4288 c, t dbSNP:202010937
4315 4315 a, g dbSNP:199878100
4316 4316 c, g dbSNP:201021066
4347 4347 a, g dbSNP:201846922
4355 4355 c, t dbSNP:200274678
4356 4356 a, g dbSNP:334349
4374 4374 a, g dbSNP:202139828
4389 4389 a, g dbSNP:200520116
4397 4397 a, g dbSNP:201591510
4400 4400 c, t dbSNP:199594054
4402 4402 a, g dbSNP:200238696
4411 4411 c, t dbSNP:201552761
4412 4412 a, g dbSNP:199736646
4433 4433 c, t dbSNP:200813968
4458 4458 g, t dbSNP:201689327
4461 4461 a, g dbSNP:199520869
4473 4473 g, t dbSNP:144871415
4478 4478 c, t dbSNP:200836217
4492 4492 a, t dbSNP:202035846
4512 4512 c, t dbSNP:200010917
4533 4533 c, t dbSNP:200777095
4534 4534 a, g dbSNP:28427103
4561 4561 a, g dbSNP:773581822
4580 4580 a, g dbSNP:529885530
4611 4611 a, g dbSNP:201599459
4615 4615 a, g dbSNP:200138586
4639 4639 a, g dbSNP:201249841
4640 4640 a, c dbSNP:202000313
4650 4650 a, g dbSNP:191007659
4659 4659 a, g dbSNP:543672032
4661 4661 a, g dbSNP:200225987
4665 4665 a, g dbSNP:201277448
4671 4671 a, c, g dbSNP:202129409
4679 4679 c, g dbSNP:773179495
4685 4685 c, g, t dbSNP:200301959
4686 4686 c, t dbSNP:201273317
4697 4697 a, g dbSNP:199540214
4701 4701 a, g dbSNP:11544424
4706 4706 c, t dbSNP:200525939
4747 4747 a, c dbSNP:201595773
4748 4748 c, t dbSNP:148797981
4762 4762 c, t dbSNP:200734120
4772 4772 g, t dbSNP:201601841
4774 4774 a, g dbSNP:142454519
4775 4775 a, g dbSNP:766905645
4777 4777 a, g dbSNP:199752579
4779 4779 a, c dbSNP:200620396
4781 4781 a, g dbSNP:3739798
4783 4783 a, g dbSNP:199886589
4791 4791 c, t dbSNP:201191549
4793 4793 c, t dbSNP:151310060
4801 4801 c, g dbSNP:202040220
4806 4806 c, t dbSNP:199982490
4812 4812 a, c dbSNP:201114226
4817 4817 c, t dbSNP:117440593
4818 4818 c, t dbSNP:78385793
4833 4833 c, t dbSNP:201094276
4842 4842 c, g dbSNP:420549
4846 4846 a, g dbSNP:755731287
4852 4852 a, g, t dbSNP:200228516
4854 4854 a, g dbSNP:140654961
4862 4862 a, g dbSNP:202218587
4870 4870 a, g dbSNP:200374520
4873 4873 c, g dbSNP:201113438
4908 4908 c, t dbSNP:199531451
4917 4917 a, g dbSNP:200676329
4922 4922 c, t dbSNP:145719397
4923 4923 c, t dbSNP:199642245
4924 4924 a, g dbSNP:200742860
4932 4932 a, g dbSNP:201896896
4938 4938 g, t dbSNP:200080374
4946 4946 a, g dbSNP:200724388
4955 4955 g, t dbSNP:201706420
4982 4982 a, g dbSNP:199858917
4984 4984 g, t dbSNP:201143384
4985 4985 -, a dbSNP:78078491
5004 5004 c, t dbSNP:146582850
5014 5014 c, t dbSNP:199969402
5023 5023 a, g dbSNP:201094409
5024 5024 g, t dbSNP:568480971
5037 5037 a, c dbSNP:571974570
5038 5038 c, g, t dbSNP:201952588
5050 5050 g, t dbSNP:534357285
5059 5059 g, t dbSNP:200562618
5093 5093 a, g dbSNP:554828293
5099 5099 c, t dbSNP:201157110
5100 5100 a, c dbSNP:201723845
5118 5118 a, g dbSNP:200245074
5121 5121 c, t dbSNP:201287805
5156 5156 a, g dbSNP:574691862
5169 5169 a, g dbSNP:564200861
5170 5170 a, t dbSNP:199726281
5181 5181 -, a dbSNP:781486193
5211 5211 a, g dbSNP:757835312
5254 5254 a, g dbSNP:200670357
5257 5257 g, t dbSNP:201522923
5260 5260 a, g dbSNP:563433922
5261 5261 a, g dbSNP:535550887
5264 5264 a, t dbSNP:181994273
5269 5269 a, g dbSNP:200775937
5287 5287 g, t dbSNP:201764616
5291 5291 c, t dbSNP:199961896
5292 5292 a, g dbSNP:559623340
5315 5315 a, g dbSNP:200535063
5335 5335 c, t dbSNP:201887512
5336 5336 a, g dbSNP:200173366
5343 5343 c, t dbSNP:377612306
5346 5346 c, t dbSNP:201101442
5354 5354 a, g dbSNP:141277814
5372 5372 a, g dbSNP:199803452
5386 5386 c, t dbSNP:186157987
5391 5391 a, c dbSNP:201848660
5393 5393 a, g dbSNP:768088879
5432 5432 a, g dbSNP:200275772
5434 5434 c, t dbSNP:190633391
5435 5435 a, g dbSNP:531799828
5489 5489 c, t dbSNP:200772657
5490 5490 c, t dbSNP:201957037
5511 5511 a, g dbSNP:200567981
5535 5535 c, g dbSNP:114704997
5536 5536 a, g dbSNP:199582297
5549 5549 g, t dbSNP:200241838
5575 5575 c, g dbSNP:550863468
5583 5583 a, g dbSNP:201535475
5586 5586 a, g dbSNP:199718989
5588 5588 c, g dbSNP:200721028
5596 5596 a, t dbSNP:41283640
5647 5647 a, g dbSNP:199511095
5651 5651 c, t dbSNP:200932500
5666 5666 a, t dbSNP:201831473
5671 5671 a, g dbSNP:200013714
5677 5677 g, t dbSNP:200780252
5686 5686 a, g dbSNP:201600236
5692 5692 c, t dbSNP:200142252
5703 5703 g, t dbSNP:570685518
5719 5719 c, g dbSNP:201105741
5745 5745 a, g dbSNP:202187992
5758 5758 a, g dbSNP:200206515
5760 5760 a, g dbSNP:201385076
5763 5763 g, t dbSNP:202104135
5769 5769 a, t dbSNP:550614032
5776 5776 c, t dbSNP:200270666
5782 5782 g, t dbSNP:201343315
5792 5792 a, t dbSNP:182830158
5834 5834 c, t dbSNP:200414044
5835 5835 -, ttatg dbSNP:747830813
5849 5849 a, g dbSNP:201453868
5851 5851 c, t dbSNP:199650257
5856 5856 c, g, t dbSNP:41283642
5867 5867 c, t dbSNP:202070537
5885 5885 a, g dbSNP:199756594
5887 5887 c, t dbSNP:200621336
5911 5911 c, t dbSNP:554310366
5912 5912 a, g dbSNP:201446431
5922 5922 a, g dbSNP:199892683
5923 5923 c, t dbSNP:201313404
5928 5928 c, t dbSNP:201836319
5931 5931 a, g dbSNP:200033182
5935 5935 a, g dbSNP:557308076
5936 5936 c, t dbSNP:577095630
5944 5944 a, g dbSNP:200967869

Target ORF information:

RefSeq Version XM_011518948
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens transforming growth factor, beta receptor 1 (TGFBR1), transcript variant X2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011518948

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
ATGTGTATAG CTGAAATTGA CTTAATTCCT CGAGATAGGC CGTTTGTATG TGCACCCTCT 
TCAAAAACTG GGTCTGTGAC TACAACATAT TGCTGCAATC AGGACCATTG CAATAAAATA
GAACTTCCAA CTACTGGCCC TTTTTCAGTA AAGTCATCAC CTGGCCTTGG TCCTGTGGAA
CTGGCAGCTG TCATTGCTGG ACCAGTGTGC TTCGTCTGCA TCTCACTCAT GTTGATGGTC
TATATCTGCC ACAACCGCAC TGTCATTCAC CATCGAGTGC CAAATGAAGA GGACCCTTCA
TTAGATCGCC CTTTTATTTC AGAGGGTACT ACGTTGAAAG ACTTAATTTA TGATATGACA
ACGTCAGGTT CTGGCTCAGG TTTACCATTG CTTGTTCAGA GAACAATTGC GAGAACTATT
GTGTTACAAG AAAGCATTGG CAAAGGTCGA TTTGGAGAAG TTTGGAGAGG AAAGTGGCGG
GGAGAAGAAG TTGCTGTTAA GATATTCTCC TCTAGAGAAG AACGTTCGTG GTTCCGTGAG
GCAGAGATTT ATCAAACTGT AATGTTACGT CATGAAAACA TCCTGGGATT TATAGCAGCA
GACAATAAAG ACAATGGTAC TTGGACTCAG CTCTGGTTGG TGTCAGATTA TCATGAGCAT
GGATCCCTTT TTGATTACTT AAACAGATAC ACAGTTACTG TGGAAGGAAT GATAAAACTT
GCTCTGTCCA CGGCGAGCGG TCTTGCCCAT CTTCACATGG AGATTGTTGG TACCCAAGGA
AAGCCAGCCA TTGCTCATAG AGATTTGAAA TCAAAGAATA TCTTGGTAAA GAAGAATGGA
ACTTGCTGTA TTGCAGACTT AGGACTGGCA GTAAGACATG ATTCAGCCAC AGATACCATT
GATATTGCTC CAAACCACAG AGTGGGAACA AAAAGGTACA TGGCCCCTGA AGTTCTCGAT
GATTCCATAA ATATGAAACA TTTTGAATCC TTCAAACGTG CTGACATCTA TGCAATGGGC
TTAGTATTCT GGGAAATTGC TCGACGATGT TCCATTGGTG GAATTCATGA AGATTACCAA
CTGCCTTATT ATGATCTTGT ACCTTCTGAC CCATCAGTTG AAGAAATGAG AAAAGTTGTT
TGTGAACAGA AGTTAAGGCC AAATATCCCA AACAGATGGC AGAGCTGTGA AGCCTTGAGA
GTAATGGCTA AAATTATGAG AGAATGTTGG TATGCCAATG GAGCAGCTAG GCTTACAGCA
TTGCGGATTA AGAAAACATT ATCGCAACTC AGTCAACAGG AAGGCATCAA AATGTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu60975
Accession Version XM_011518949.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1305bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector Document: User manual_GenEZ ORF Clone Products.pdf (pdf)
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags Document: MSDS_GenEZ ORF Clone Products.pdf (pdf)
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product TGF-beta receptor type-1 isoform X3
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_008470.20) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
ATGTGTATAG CTGAAATTGA CTTAATTCCT CGAGATAGGC CGTTTGTATG TGCACCCTCT 
TCAAAAACTG GGTCTGTGAC TACAACATAT TGCTGCAATC AGGACCATTG CAATAAAATA
GAACTTCCAA CTACTGTAAA GTCATCACCT GGCCTTGGTC CTGTGGAACT GGCAGCTGTC
ATTGCTGGAC CAGTGTGCTT CGTCTGCATC TCACTCATGT TGATGGTCTA TATCTGCCAC
AACCGCACTG TCATTCACCA TCGAGTGCCA AATGAAGAGG ACCCTTCATT AGATCGCCCT
TTTATTTCAG AGGGTACTAC GTTGAAAGAC TTAATTTATG ATATGACAAC GTCAGGTTCT
GGCTCAGGTT TACCATTGCT TGTTCAGAGA ACAATTGCGA GAACTATTGT GTTACAAGAA
AGCATTGGCA AAGGTCGATT TGGAGAAGTT TGGAGAGGAA AGTGGCGGGG AGAAGAAGTT
GCTGTTAAGA TATTCTCCTC TAGAGAAGAA CGTTCGTGGT TCCGTGAGGC AGAGATTTAT
CAAACTGTAA TGTTACGTCA TGAAAACATC CTGGGATTTA TAGCAGCAGA CAATAAAGAC
AATGGTACTT GGACTCAGCT CTGGTTGGTG TCAGATTATC ATGAGCATGG ATCCCTTTTT
GATTACTTAA ACAGATACAC AGTTACTGTG GAAGGAATGA TAAAACTTGC TCTGTCCACG
GCGAGCGGTC TTGCCCATCT TCACATGGAG ATTGTTGGTA CCCAAGGAAA GCCAGCCATT
GCTCATAGAG ATTTGAAATC AAAGAATATC TTGGTAAAGA AGAATGGAAC TTGCTGTATT
GCAGACTTAG GACTGGCAGT AAGACATGAT TCAGCCACAG ATACCATTGA TATTGCTCCA
AACCACAGAG TGGGAACAAA AAGGTACATG GCCCCTGAAG TTCTCGATGA TTCCATAAAT
ATGAAACATT TTGAATCCTT CAAACGTGCT GACATCTATG CAATGGGCTT AGTATTCTGG
GAAATTGCTC GACGATGTTC CATTGGTGGA ATTCATGAAG ATTACCAACT GCCTTATTAT
GATCTTGTAC CTTCTGACCC ATCAGTTGAA GAAATGAGAA AAGTTGTTTG TGAACAGAAG
TTAAGGCCAA ATATCCCAAA CAGATGGCAG AGCTGTGAAG CCTTGAGAGT AATGGCTAAA
ATTATGAGAG AATGTTGGTA TGCCAATGGA GCAGCTAGGC TTACAGCATT GCGGATTAAG
AAAACATTAT CGCAACTCAG TCAACAGGAA GGCATCAAAA TGTAA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqXP_011517251.1
CDS180..1484
Misc Feature(1)180..314(+)
Misc Feature(2)495..581(+)
Misc Feature(3)585..1442(+)
Misc Feature(4)597..1460(+)
Misc Feature(5)603..1103(+)
Misc Feature(6)603..1025(+)
Misc Feature(7)615..1103(+)
Misc Feature(8)696..773(+)
Misc Feature(9)1020..1103(+)
Translation
Position Chain Variation Link
59 59 a, g dbSNP:535608236
71 71 a, g, t dbSNP:779055286
76 76 a, g dbSNP:772361141
85 85 a, g dbSNP:750150798
92 92 c, t dbSNP:201267786
93 93 a, t dbSNP:543397817
97 97 -, c dbSNP:772089863
106 106 a, g dbSNP:387906696
107 107 c, t dbSNP:369226180
113 113 a, t dbSNP:776285294
126 126 c, g dbSNP:587776865
128 128 a, g dbSNP:761368421
140 140 c, t dbSNP:199534451
159 159 a, g dbSNP:200779997
160 160 a, g dbSNP:765004526
164 164 a, g dbSNP:112051451
167 167 a, t dbSNP:762638283
171 171 c, t dbSNP:766157497
175 175 a, g dbSNP:727503469
179 179 c, t dbSNP:145033378
186 186 a, t dbSNP:111513627
194 194 a, c dbSNP:201910738
197 197 c, t dbSNP:200543076
201 201 g, t dbSNP:753933625
220 220 c, t dbSNP:757374917
221 221 a, g dbSNP:200091200
225 225 g, t dbSNP:746141820
239 239 g, t dbSNP:772324783
242 242 -, a dbSNP:147107882
264 264 a, t dbSNP:780295872
266 266 a, c dbSNP:747332492
269 269 c, t dbSNP:550395617
276 276 a, g dbSNP:769320006
277 277 a, g dbSNP:200860457
287 287 c, t dbSNP:201771506
290 290 c, t dbSNP:149417020
302 302 a, g dbSNP:769471584
306 306 c, g dbSNP:199904970
309 309 a, g dbSNP:762573778
314 314 a, g, t dbSNP:371415976
317 317 a, g dbSNP:766347880
325 325 c, t dbSNP:370568025
329 329 a, t dbSNP:755249354
330 330 a, g dbSNP:781729436
341 341 g, t dbSNP:773635581
342 342 a, g dbSNP:373391549
348 348 c, g dbSNP:756586874
354 354 c, g dbSNP:778289813
359 359 c, g dbSNP:749733473
364 364 c, g dbSNP:770511883
372 372 a, g dbSNP:730880222
380 380 c, t dbSNP:773845018
381 381 a, g dbSNP:745576967
387 387 a, g dbSNP:148176750
393 393 c, t dbSNP:749651186
406 406 g, t dbSNP:775267361
411 411 a, g dbSNP:760422619
412 412 c, t dbSNP:75857126
418 418 a, g dbSNP:768500160
423 423 c, t dbSNP:776680716
424 424 a, g dbSNP:539413187
429 429 a, g dbSNP:56014374
435 435 c, t dbSNP:751679796
442 442 c, g dbSNP:147146713
450 450 a, c dbSNP:113982335
451 451 a, g dbSNP:767785290
467 467 a, g dbSNP:753147276
471 471 c, g dbSNP:756547201
475 475 a, g dbSNP:777965779
478 478 c, g dbSNP:756643977
479 479 c, t dbSNP:754431973
488 488 a, g dbSNP:140245968
493 493 g, t dbSNP:121918713
495 495 a, t dbSNP:201137894
499 499 c, t dbSNP:745324433
500 500 a, g dbSNP:190878719
504 504 a, g dbSNP:779641991
529 529 a, c, t dbSNP:144313652
530 530 a, g, t dbSNP:538382054
540 540 c, g dbSNP:769785561
544 544 c, t dbSNP:774583379
554 554 a, t dbSNP:200679996
568 568 a, g dbSNP:397517032
571 571 c, t dbSNP:121918712
573 573 a, g dbSNP:781042616
578 578 a, g dbSNP:201497553
585 585 a, g dbSNP:200018073
605 605 a, t dbSNP:769871453
612 612 g, t dbSNP:727503470
644 644 a, g dbSNP:201021249
650 650 a, g dbSNP:201444476
652 652 a, g dbSNP:772339721
674 674 c, t dbSNP:202156059
690 690 c, t dbSNP:775429965
692 692 c, t dbSNP:200078591
694 694 c, t dbSNP:111854391
695 695 a, g dbSNP:201112150
713 713 a, g dbSNP:764165477
725 725 c, t dbSNP:202189494
732 732 c, t dbSNP:777077652
740 740 c, t dbSNP:762125867
751 751 a, t dbSNP:397517033
767 767 a, c dbSNP:200158200
771 771 a, g dbSNP:727503471
781 781 a, g dbSNP:201475375
782 782 c, t dbSNP:147388628
785 785 c, t dbSNP:200511345
807 807 c, g dbSNP:112300506
816 816 c, t dbSNP:755827803
833 833 c, t dbSNP:371269876
834 834 c, t dbSNP:201605956
843 843 c, t dbSNP:191136014
844 844 a, g dbSNP:35974499
850 850 a, g dbSNP:199759998
855 855 a, t dbSNP:200560562
860 860 a, g dbSNP:201943631
861 861 a, g dbSNP:757284158
864 864 a, g dbSNP:764452904
867 867 a, g dbSNP:199822546
869 869 a, g dbSNP:369881419
888 888 c, g, t dbSNP:768667498
890 890 c, t dbSNP:748434255
898 898 c, t dbSNP:200518416
899 899 a, g dbSNP:201323409
901 901 c, t dbSNP:202010361
902 902 a, g dbSNP:139090459
905 905 c, t dbSNP:200912890
906 906 a, g dbSNP:760079636
917 917 c, t dbSNP:767005593
924 924 a, c dbSNP:752190665
925 925 g, t dbSNP:121918710
930 930 a, c dbSNP:760419678
965 965 c, t dbSNP:199770942
966 966 -, agagat dbSNP:727504383
980 980 a, g dbSNP:761512764
981 981 a, g dbSNP:113911127
1004 1004 c, t dbSNP:192662552
1012 1012 a, c, g dbSNP:113786548
1037 1037 a, c, g dbSNP:758280185
1041 1041 a, g dbSNP:779100123
1063 1063 c, g dbSNP:201050937
1082 1082 c, t dbSNP:368402450
1091 1091 a, g dbSNP:777805295
1097 1097 a, c dbSNP:7861780
1110 1110 g, t dbSNP:746666082
1111 1111 c, g dbSNP:746047431
1113 1113 c, t dbSNP:760555508
1124 1124 c, t dbSNP:115324990
1133 1133 c, t dbSNP:747584981
1139 1139 c, t dbSNP:769218243
1141 1141 c, t dbSNP:199574997
1158 1158 g, t dbSNP:747644508
1165 1165 a, g dbSNP:200657153
1171 1171 a, g dbSNP:121918711
1175 1175 c, t dbSNP:200358981
1177 1177 a, g dbSNP:762486367
1180 1180 c, g, t dbSNP:557200755
1182 1182 a, g dbSNP:143435050
1188 1188 a, c, t dbSNP:200062984
1190 1190 a, g dbSNP:757399188
1191 1191 c, g dbSNP:146549837
1204 1204 c, t dbSNP:200986584
1209 1209 c, t dbSNP:200595614
1212 1212 c, t dbSNP:387906697
1221 1221 a, g dbSNP:764050602
1235 1235 a, t dbSNP:781386406
1247 1247 a, g dbSNP:753301297
1249 1249 g, t dbSNP:756570466
1250 1250 g, t dbSNP:368928967
1256 1256 c, t dbSNP:201163170
1257 1257 c, t dbSNP:201745016
1286 1286 c, t dbSNP:770604680
1296 1296 a, g dbSNP:778579239
1299 1299 a, g dbSNP:745499424
1316 1316 a, g dbSNP:771962930
1325 1325 a, g dbSNP:775143255
1327 1327 -, c dbSNP:111820381
1330 1330 a, c dbSNP:760666606
1350 1350 a, g dbSNP:768418563
1359 1359 g, t dbSNP:776749573
1360 1360 a, c dbSNP:748073284
1366 1366 a, g dbSNP:556555554
1371 1371 a, g dbSNP:199926741
1381 1381 c, t dbSNP:774565396
1392 1392 a, t dbSNP:759805984
1397 1397 g, t dbSNP:767589799
1405 1405 a, g, t dbSNP:141259922
1407 1407 a, g dbSNP:377194685
1416 1416 a, g dbSNP:730880223
1428 1428 c, t dbSNP:111818778
1431 1431 c, t dbSNP:111426349
1432 1432 a, c, g dbSNP:113605875
1451 1451 a, g dbSNP:144985585
1459 1459 a, g dbSNP:764733540
1461 1461 c, g dbSNP:749879202
1469 1469 a, g dbSNP:200055681
1489 1489 a, g dbSNP:201254457
1491 1491 a, g dbSNP:779531038
1504 1504 c, t dbSNP:369611795
1506 1506 c, g dbSNP:754777682
1509 1509 c, t dbSNP:202041245
1510 1510 g, t dbSNP:781117226
1510 1510 -, t dbSNP:746953792
1515 1515 c, t dbSNP:201753435
1521 1521 c, g dbSNP:769785618
1530 1530 c, t dbSNP:192327847
1536 1536 a, t dbSNP:745898677
1540 1540 a, g dbSNP:994
1553 1553 a, g dbSNP:868
1566 1566 a, t dbSNP:200966435
1584 1584 g, t dbSNP:201855724
1598 1598 c, t dbSNP:200434439
1603 1603 g, t dbSNP:184489732
1604 1604 c, t dbSNP:201350756
1616 1616 a, g dbSNP:767616657
1630 1630 -, c dbSNP:35702937
1671 1671 c, t dbSNP:202238690
1680 1680 c, t dbSNP:200533591
1689 1689 c, t dbSNP:201419046
1690 1690 a, g dbSNP:199609928
1695 1695 a, t dbSNP:200495698
1711 1711 a, t dbSNP:760980107
1728 1728 a, g dbSNP:560210246
1736 1736 c, t dbSNP:201563225
1781 1781 c, t dbSNP:199683401
1795 1795 a, g dbSNP:200804500
1806 1806 a, c dbSNP:528867293
1822 1822 a, g dbSNP:201682869
1823 1823 g, t dbSNP:199861787
1829 1829 a, g dbSNP:200832519
1841 1841 a, t dbSNP:368380699
1842 1842 c, t dbSNP:764209146
1844 1844 a, g dbSNP:145692006
1855 1855 c, t dbSNP:200019371
1856 1856 c, t dbSNP:200786932
1859 1859 c, t dbSNP:201903995
1890 1890 a, t dbSNP:750730238
1900 1900 c, g dbSNP:200063976
1913 1913 c, g dbSNP:201260283
1925 1925 c, t dbSNP:202012098
1940 1940 g, t dbSNP:200245567
1954 1954 a, g dbSNP:201142879
1957 1957 -, t dbSNP:568494416
1957 1957 a, g dbSNP:202133538
1966 1966 g, t dbSNP:200294552
1969 1969 c, g dbSNP:531460959
1986 1986 c, t dbSNP:201269197
1992 1992 -, tctta dbSNP:777186940
1997 1997 a, t dbSNP:199521592
2004 2004 c, t dbSNP:200514984
2007 2007 a, g dbSNP:11568807
2022 2022 c, t dbSNP:199578935
2036 2036 a, g dbSNP:200511595
2039 2039 a, g dbSNP:201606447
2043 2043 a, g dbSNP:559337318
2046 2046 c, g dbSNP:199765042
2050 2050 c, t dbSNP:11568808
2058 2058 a, g dbSNP:201687617
2063 2063 c, g dbSNP:754640242
2075 2075 -, tt dbSNP:750491076
2113 2113 a, c dbSNP:199867951
2121 2121 a, g dbSNP:201205567
2196 2196 a, g dbSNP:780634517
2198 2198 a, g dbSNP:201984381
2212 2212 a, g dbSNP:199993828
2240 2240 c, t dbSNP:200926268
2262 2262 a, g dbSNP:202158467
2273 2273 a, g dbSNP:200428927
2280 2280 a, c dbSNP:201076760
2315 2315 a, c dbSNP:201996934
2327 2327 g, t dbSNP:200224469
2333 2333 c, t dbSNP:201615730
2361 2361 a, g dbSNP:199734350
2368 2368 a, g dbSNP:334348
2374 2374 a, g dbSNP:201052504
2376 2376 a, g dbSNP:199549381
2377 2377 a, g dbSNP:200679214
2383 2383 c, t dbSNP:36049024
2397 2397 c, t dbSNP:201990134
2405 2405 g, t dbSNP:34325659
2410 2410 c, t dbSNP:199584415
2433 2433 a, g dbSNP:189593120
2451 2451 c, g dbSNP:200755777
2457 2457 c, g dbSNP:756852117
2462 2462 a, g dbSNP:35870119
2488 2488 a, t dbSNP:35607843
2490 2490 c, t dbSNP:201910377
2518 2518 a, g dbSNP:200005909
2520 2520 g, t dbSNP:201098935
2530 2530 g, t dbSNP:201701125
2533 2533 c, t dbSNP:11568809
2547 2547 a, g dbSNP:201191454
2550 2550 a, g dbSNP:778564621
2561 2561 a, g dbSNP:539294464
2572 2572 c, t dbSNP:202224779
2576 2576 a, g dbSNP:559316578
2587 2587 c, g dbSNP:199978072
2595 2595 c, t dbSNP:201110333
2638 2638 c, t dbSNP:141078676
2655 2655 c, t dbSNP:10988732
2663 2663 a, g dbSNP:193056376
2666 2666 c, t dbSNP:200376574
2667 2667 a, g dbSNP:184564501
2690 2690 c, g dbSNP:201746454
2691 2691 a, g dbSNP:200186059
2716 2716 c, t dbSNP:201621825
2723 2723 c, t dbSNP:199740407
2724 2724 a, g dbSNP:200689459
2728 2728 a, g dbSNP:201519485
2743 2743 c, g, t dbSNP:150247576
2744 2744 a, g dbSNP:200765185
2752 2752 c, t dbSNP:541995278
2753 2753 c, g, t dbSNP:189032587
2754 2754 c, t dbSNP:774659140
2772 2772 g, t dbSNP:199956399
2777 2777 c, g, t dbSNP:200739404
2800 2800 c, g dbSNP:201894361
2804 2804 a, g dbSNP:138860379
2808 2808 c, t dbSNP:564868044
2816 2816 a, g dbSNP:200076723
2826 2826 a, g dbSNP:201116349
2827 2827 c, t dbSNP:11568810
2830 2830 a, g dbSNP:567642330
2848 2848 c, t dbSNP:530171542
2849 2849 g, t dbSNP:199891042
2853 2853 a, g dbSNP:200970226
2860 2860 c, g dbSNP:201863088
2862 2862 a, g dbSNP:200278937
2889 2889 c, t dbSNP:201453348
2894 2894 c, t dbSNP:201952413
2896 2896 c, t dbSNP:200562457
2912 2912 c, g dbSNP:11568811
2931 2931 a, t dbSNP:199588065
2935 2935 c, t dbSNP:200560836
2939 2939 c, t dbSNP:760928585
2940 2940 a, g dbSNP:769029753
2993 2993 g, t dbSNP:570039754
2999 2999 a, g dbSNP:11568812
3013 3013 a, g dbSNP:559280038
3025 3025 c, t dbSNP:199733000
3026 3026 g, t dbSNP:776540727
3051 3051 a, g dbSNP:200669525
3056 3056 a, g dbSNP:79410528
3058 3058 a, g dbSNP:199522012
3066 3066 c, t dbSNP:200943776
3087 3087 a, g dbSNP:201500025
3096 3096 c, t dbSNP:200036408
3098 3098 a, g dbSNP:200791684
3124 3124 a, g dbSNP:201604963
3143 3143 c, t dbSNP:200082162
3170 3170 -, ta dbSNP:780605360
3172 3172 c, t dbSNP:201101156
3181 3181 c, t dbSNP:181403208
3194 3194 a, g dbSNP:200197062
3232 3232 a, g dbSNP:201222590
3235 3235 c, t dbSNP:202128625
3236 3236 a, g dbSNP:200296344
3243 3243 a, c dbSNP:183812806
3256 3256 a, c dbSNP:201191009
3262 3262 a, g dbSNP:200566464
3282 3282 c, t dbSNP:138248864
3283 3283 a, g dbSNP:199580278
3288 3288 a, g dbSNP:200656974
3309 3309 a, g dbSNP:201607717
3352 3352 a, g dbSNP:199765790
3353 3353 c, g dbSNP:200570178
3362 3362 g, t dbSNP:201434094
3425 3425 a, t dbSNP:199811787
3444 3444 c, t dbSNP:201307737
3472 3472 g, t dbSNP:201829833
3489 3489 g, t dbSNP:144216869
3527 3527 a, g dbSNP:527618646
3554 3554 a, t dbSNP:540978964
3565 3565 -, gtt dbSNP:75796733
3565 3565 g, t dbSNP:200898127
3566 3566 g, t dbSNP:112113922
3570 3570 g, t dbSNP:148063684
3574 3574 a, g, t dbSNP:201152885
3576 3576 -, t dbSNP:376556150
3576 3576 g, t dbSNP:199545273
3577 3577 g, t dbSNP:202187266
3577 3577 -, t dbSNP:200529894
3578 3578 g, t dbSNP:200204084
3579 3579 g, t dbSNP:201780012
3580 3580 -, tg dbSNP:541820908
3580 3580 g, t dbSNP:200867114
3581 3581 -, g, gt dbSNP:61566226
3582 3582 g, t dbSNP:201738100
3583 3583 g, t dbSNP:199659996
3584 3584 g, t dbSNP:532530728
3587 3587 -, g dbSNP:36064078
3587 3587 g, t dbSNP:7871490
3590 3590 g, t dbSNP:201054018
3596 3596 -, ttt dbSNP:199589877
3596 3596 g, t dbSNP:60885995
3601 3601 g, t dbSNP:181680115
3630 3630 c, t dbSNP:200675329
3638 3638 a, g dbSNP:201153037
3663 3663 -, a dbSNP:373576679
3718 3718 a, g dbSNP:754588954
3730 3730 g, t dbSNP:552650250
3737 3737 c, t dbSNP:199645690
3746 3746 g, t dbSNP:200653031
3758 3758 a, g dbSNP:202068970
3877 3877 a, g dbSNP:77810552
3894 3894 c, t dbSNP:200722893
3895 3895 a, g dbSNP:11568813
3899 3899 g, t dbSNP:140497381
3910 3910 a, g dbSNP:185811148
3935 3935 g, t dbSNP:201140077
3957 3957 a, t dbSNP:202106034
3966 3966 -, gaaa dbSNP:747408434
4004 4004 c, t dbSNP:200032389
4005 4005 c, t dbSNP:200985953
4006 4006 a, g dbSNP:202239214
4020 4020 a, c dbSNP:200378819
4040 4040 a, t dbSNP:200553684
4057 4057 c, t dbSNP:537279747
4059 4059 a, g dbSNP:201156487
4072 4072 c, t dbSNP:201719827
4074 4074 a, c dbSNP:11544423
4102 4102 c, g dbSNP:200240411
4104 4104 a, g dbSNP:201765733
4111 4111 g, t dbSNP:147373120
4120 4120 a, t dbSNP:199685230
4122 4122 c, t dbSNP:555815837
4129 4129 a, c dbSNP:17724567
4130 4130 c, t dbSNP:201410594
4136 4136 a, g dbSNP:199515707
4157 4157 a, g dbSNP:749188476
4169 4169 g, t dbSNP:145043837
4178 4178 a, g dbSNP:201761492
4179 4179 a, g dbSNP:199959704
4180 4180 a, g dbSNP:200552727
4182 4182 a, g dbSNP:202073426
4187 4187 a, g dbSNP:76392135
4191 4191 c, t dbSNP:201264579
4216 4216 c, t dbSNP:202010937
4243 4243 a, g dbSNP:199878100
4244 4244 c, g dbSNP:201021066
4275 4275 a, g dbSNP:201846922
4283 4283 c, t dbSNP:200274678
4284 4284 a, g dbSNP:334349
4302 4302 a, g dbSNP:202139828
4317 4317 a, g dbSNP:200520116
4325 4325 a, g dbSNP:201591510
4328 4328 c, t dbSNP:199594054
4330 4330 a, g dbSNP:200238696
4339 4339 c, t dbSNP:201552761
4340 4340 a, g dbSNP:199736646
4361 4361 c, t dbSNP:200813968
4386 4386 g, t dbSNP:201689327
4389 4389 a, g dbSNP:199520869
4401 4401 g, t dbSNP:144871415
4406 4406 c, t dbSNP:200836217
4420 4420 a, t dbSNP:202035846
4440 4440 c, t dbSNP:200010917
4461 4461 c, t dbSNP:200777095
4462 4462 a, g dbSNP:28427103
4489 4489 a, g dbSNP:773581822
4508 4508 a, g dbSNP:529885530
4539 4539 a, g dbSNP:201599459
4543 4543 a, g dbSNP:200138586
4567 4567 a, g dbSNP:201249841
4568 4568 a, c dbSNP:202000313
4578 4578 a, g dbSNP:191007659
4587 4587 a, g dbSNP:543672032
4589 4589 a, g dbSNP:200225987
4593 4593 a, g dbSNP:201277448
4599 4599 a, c, g dbSNP:202129409
4607 4607 c, g dbSNP:773179495
4613 4613 c, g, t dbSNP:200301959
4614 4614 c, t dbSNP:201273317
4625 4625 a, g dbSNP:199540214
4629 4629 a, g dbSNP:11544424
4634 4634 c, t dbSNP:200525939
4675 4675 a, c dbSNP:201595773
4676 4676 c, t dbSNP:148797981
4690 4690 c, t dbSNP:200734120
4700 4700 g, t dbSNP:201601841
4702 4702 a, g dbSNP:142454519
4703 4703 a, g dbSNP:766905645
4705 4705 a, g dbSNP:199752579
4707 4707 a, c dbSNP:200620396
4709 4709 a, g dbSNP:3739798
4711 4711 a, g dbSNP:199886589
4719 4719 c, t dbSNP:201191549
4721 4721 c, t dbSNP:151310060
4729 4729 c, g dbSNP:202040220
4734 4734 c, t dbSNP:199982490
4740 4740 a, c dbSNP:201114226
4745 4745 c, t dbSNP:117440593
4746 4746 c, t dbSNP:78385793
4761 4761 c, t dbSNP:201094276
4770 4770 c, g dbSNP:420549
4774 4774 a, g dbSNP:755731287
4780 4780 a, g, t dbSNP:200228516
4782 4782 a, g dbSNP:140654961
4790 4790 a, g dbSNP:202218587
4798 4798 a, g dbSNP:200374520
4801 4801 c, g dbSNP:201113438
4836 4836 c, t dbSNP:199531451
4845 4845 a, g dbSNP:200676329
4850 4850 c, t dbSNP:145719397
4851 4851 c, t dbSNP:199642245
4852 4852 a, g dbSNP:200742860
4860 4860 a, g dbSNP:201896896
4866 4866 g, t dbSNP:200080374
4874 4874 a, g dbSNP:200724388
4883 4883 g, t dbSNP:201706420
4910 4910 a, g dbSNP:199858917
4912 4912 g, t dbSNP:201143384
4913 4913 -, a dbSNP:78078491
4932 4932 c, t dbSNP:146582850
4942 4942 c, t dbSNP:199969402
4951 4951 a, g dbSNP:201094409
4952 4952 g, t dbSNP:568480971
4965 4965 a, c dbSNP:571974570
4966 4966 c, g, t dbSNP:201952588
4978 4978 g, t dbSNP:534357285
4987 4987 g, t dbSNP:200562618
5021 5021 a, g dbSNP:554828293
5027 5027 c, t dbSNP:201157110
5028 5028 a, c dbSNP:201723845
5046 5046 a, g dbSNP:200245074
5049 5049 c, t dbSNP:201287805
5084 5084 a, g dbSNP:574691862
5097 5097 a, g dbSNP:564200861
5098 5098 a, t dbSNP:199726281
5109 5109 -, a dbSNP:781486193
5139 5139 a, g dbSNP:757835312
5182 5182 a, g dbSNP:200670357
5185 5185 g, t dbSNP:201522923
5188 5188 a, g dbSNP:563433922
5189 5189 a, g dbSNP:535550887
5192 5192 a, t dbSNP:181994273
5197 5197 a, g dbSNP:200775937
5215 5215 g, t dbSNP:201764616
5219 5219 c, t dbSNP:199961896
5220 5220 a, g dbSNP:559623340
5243 5243 a, g dbSNP:200535063
5263 5263 c, t dbSNP:201887512
5264 5264 a, g dbSNP:200173366
5271 5271 c, t dbSNP:377612306
5274 5274 c, t dbSNP:201101442
5282 5282 a, g dbSNP:141277814
5300 5300 a, g dbSNP:199803452
5314 5314 c, t dbSNP:186157987
5319 5319 a, c dbSNP:201848660
5321 5321 a, g dbSNP:768088879
5360 5360 a, g dbSNP:200275772
5362 5362 c, t dbSNP:190633391
5363 5363 a, g dbSNP:531799828
5417 5417 c, t dbSNP:200772657
5418 5418 c, t dbSNP:201957037
5439 5439 a, g dbSNP:200567981
5463 5463 c, g dbSNP:114704997
5464 5464 a, g dbSNP:199582297
5477 5477 g, t dbSNP:200241838
5503 5503 c, g dbSNP:550863468
5511 5511 a, g dbSNP:201535475
5514 5514 a, g dbSNP:199718989
5516 5516 c, g dbSNP:200721028
5524 5524 a, t dbSNP:41283640
5575 5575 a, g dbSNP:199511095
5579 5579 c, t dbSNP:200932500
5594 5594 a, t dbSNP:201831473
5599 5599 a, g dbSNP:200013714
5605 5605 g, t dbSNP:200780252
5614 5614 a, g dbSNP:201600236
5620 5620 c, t dbSNP:200142252
5631 5631 g, t dbSNP:570685518
5647 5647 c, g dbSNP:201105741
5673 5673 a, g dbSNP:202187992
5686 5686 a, g dbSNP:200206515
5688 5688 a, g dbSNP:201385076
5691 5691 g, t dbSNP:202104135
5697 5697 a, t dbSNP:550614032
5704 5704 c, t dbSNP:200270666
5710 5710 g, t dbSNP:201343315
5720 5720 a, t dbSNP:182830158
5762 5762 c, t dbSNP:200414044
5763 5763 -, ttatg dbSNP:747830813
5777 5777 a, g dbSNP:201453868
5779 5779 c, t dbSNP:199650257
5784 5784 c, g, t dbSNP:41283642
5795 5795 c, t dbSNP:202070537
5813 5813 a, g dbSNP:199756594
5815 5815 c, t dbSNP:200621336
5839 5839 c, t dbSNP:554310366
5840 5840 a, g dbSNP:201446431
5850 5850 a, g dbSNP:199892683
5851 5851 c, t dbSNP:201313404
5856 5856 c, t dbSNP:201836319
5859 5859 a, g dbSNP:200033182
5863 5863 a, g dbSNP:557308076
5864 5864 c, t dbSNP:577095630
5872 5872 a, g dbSNP:200967869

Target ORF information:

RefSeq Version XM_011518949
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens transforming growth factor, beta receptor 1 (TGFBR1), transcript variant X3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011518949

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
ATGTGTATAG CTGAAATTGA CTTAATTCCT CGAGATAGGC CGTTTGTATG TGCACCCTCT 
TCAAAAACTG GGTCTGTGAC TACAACATAT TGCTGCAATC AGGACCATTG CAATAAAATA
GAACTTCCAA CTACTGTAAA GTCATCACCT GGCCTTGGTC CTGTGGAACT GGCAGCTGTC
ATTGCTGGAC CAGTGTGCTT CGTCTGCATC TCACTCATGT TGATGGTCTA TATCTGCCAC
AACCGCACTG TCATTCACCA TCGAGTGCCA AATGAAGAGG ACCCTTCATT AGATCGCCCT
TTTATTTCAG AGGGTACTAC GTTGAAAGAC TTAATTTATG ATATGACAAC GTCAGGTTCT
GGCTCAGGTT TACCATTGCT TGTTCAGAGA ACAATTGCGA GAACTATTGT GTTACAAGAA
AGCATTGGCA AAGGTCGATT TGGAGAAGTT TGGAGAGGAA AGTGGCGGGG AGAAGAAGTT
GCTGTTAAGA TATTCTCCTC TAGAGAAGAA CGTTCGTGGT TCCGTGAGGC AGAGATTTAT
CAAACTGTAA TGTTACGTCA TGAAAACATC CTGGGATTTA TAGCAGCAGA CAATAAAGAC
AATGGTACTT GGACTCAGCT CTGGTTGGTG TCAGATTATC ATGAGCATGG ATCCCTTTTT
GATTACTTAA ACAGATACAC AGTTACTGTG GAAGGAATGA TAAAACTTGC TCTGTCCACG
GCGAGCGGTC TTGCCCATCT TCACATGGAG ATTGTTGGTA CCCAAGGAAA GCCAGCCATT
GCTCATAGAG ATTTGAAATC AAAGAATATC TTGGTAAAGA AGAATGGAAC TTGCTGTATT
GCAGACTTAG GACTGGCAGT AAGACATGAT TCAGCCACAG ATACCATTGA TATTGCTCCA
AACCACAGAG TGGGAACAAA AAGGTACATG GCCCCTGAAG TTCTCGATGA TTCCATAAAT
ATGAAACATT TTGAATCCTT CAAACGTGCT GACATCTATG CAATGGGCTT AGTATTCTGG
GAAATTGCTC GACGATGTTC CATTGGTGGA ATTCATGAAG ATTACCAACT GCCTTATTAT
GATCTTGTAC CTTCTGACCC ATCAGTTGAA GAAATGAGAA AAGTTGTTTG TGAACAGAAG
TTAAGGCCAA ATATCCCAAA CAGATGGCAG AGCTGTGAAG CCTTGAGAGT AATGGCTAAA
ATTATGAGAG AATGTTGGTA TGCCAATGGA GCAGCTAGGC TTACAGCATT GCGGATTAAG
AAAACATTAT CGCAACTCAG TCAACAGGAA GGCATCAAAA TGTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu60976
Accession Version XM_011518950.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1074bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector Document: User manual_GenEZ ORF Clone Products.pdf (pdf)
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags Document: MSDS_GenEZ ORF Clone Products.pdf (pdf)
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product TGF-beta receptor type-1 isoform X4
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_008470.20) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
ATGTGTATAG CTGAAATTGA CTTAATTCCT CGAGATAGGC CGTTTGTATG TGCACCCTCT 
TCAAAAACTG GGTCTGTGAC TACAACATAT TGCTGCAATC AGGACCATTG CAATAAAATA
GAACTTCCAA CTACTGGTTT ACCATTGCTT GTTCAGAGAA CAATTGCGAG AACTATTGTG
TTACAAGAAA GCATTGGCAA AGGTCGATTT GGAGAAGTTT GGAGAGGAAA GTGGCGGGGA
GAAGAAGTTG CTGTTAAGAT ATTCTCCTCT AGAGAAGAAC GTTCGTGGTT CCGTGAGGCA
GAGATTTATC AAACTGTAAT GTTACGTCAT GAAAACATCC TGGGATTTAT AGCAGCAGAC
AATAAAGACA ATGGTACTTG GACTCAGCTC TGGTTGGTGT CAGATTATCA TGAGCATGGA
TCCCTTTTTG ATTACTTAAA CAGATACACA GTTACTGTGG AAGGAATGAT AAAACTTGCT
CTGTCCACGG CGAGCGGTCT TGCCCATCTT CACATGGAGA TTGTTGGTAC CCAAGGAAAG
CCAGCCATTG CTCATAGAGA TTTGAAATCA AAGAATATCT TGGTAAAGAA GAATGGAACT
TGCTGTATTG CAGACTTAGG ACTGGCAGTA AGACATGATT CAGCCACAGA TACCATTGAT
ATTGCTCCAA ACCACAGAGT GGGAACAAAA AGGTACATGG CCCCTGAAGT TCTCGATGAT
TCCATAAATA TGAAACATTT TGAATCCTTC AAACGTGCTG ACATCTATGC AATGGGCTTA
GTATTCTGGG AAATTGCTCG ACGATGTTCC ATTGGTGGAA TTCATGAAGA TTACCAACTG
CCTTATTATG ATCTTGTACC TTCTGACCCA TCAGTTGAAG AAATGAGAAA AGTTGTTTGT
GAACAGAAGT TAAGGCCAAA TATCCCAAAC AGATGGCAGA GCTGTGAAGC CTTGAGAGTA
ATGGCTAAAA TTATGAGAGA ATGTTGGTAT GCCAATGGAG CAGCTAGGCT TACAGCATTG
CGGATTAAGA AAACATTATC GCAACTCAGT CAACAGGAAG GCATCAAAAT GTAA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqXP_011517252.1
CDS334..1407
Misc Feature(1)334..468(+)
Misc Feature(2)466..504(+)
Misc Feature(3)508..1365(+)
Misc Feature(4)520..1383(+)
Misc Feature(5)526..1026(+)
Misc Feature(6)526..948(+)
Misc Feature(7)538..1026(+)
Misc Feature(8)619..696(+)
Misc Feature(9)943..1026(+)
Translation
Position Chain Variation Link
3 3 a, g dbSNP:577998359
29 29 a, g dbSNP:375184563
37 37 a, g dbSNP:540563402
42 42 -, atgtg dbSNP:552675405
121 121 c, g, t dbSNP:771020516
146 146 a, g dbSNP:148567056
166 166 c, t dbSNP:11568753
191 191 a, g dbSNP:542480483
201 201 c, g dbSNP:755527253
202 202 a, g dbSNP:562609002
208 208 -, a dbSNP:575497750
225 225 a, g, t dbSNP:779055286
230 230 a, g dbSNP:772361141
239 239 a, g dbSNP:750150798
246 246 c, t dbSNP:201267786
247 247 a, t dbSNP:543397817
251 251 -, c dbSNP:772089863
260 260 a, g dbSNP:387906696
261 261 c, t dbSNP:369226180
267 267 a, t dbSNP:776285294
280 280 c, g dbSNP:587776865
282 282 a, g dbSNP:761368421
294 294 c, t dbSNP:199534451
313 313 a, g dbSNP:200779997
314 314 a, g dbSNP:765004526
318 318 a, g dbSNP:112051451
321 321 a, t dbSNP:762638283
325 325 c, t dbSNP:766157497
329 329 a, g dbSNP:727503469
333 333 c, t dbSNP:145033378
340 340 a, t dbSNP:111513627
348 348 a, c dbSNP:201910738
351 351 c, t dbSNP:200543076
355 355 g, t dbSNP:753933625
374 374 c, t dbSNP:757374917
375 375 a, g dbSNP:200091200
379 379 g, t dbSNP:746141820
393 393 g, t dbSNP:772324783
396 396 -, a dbSNP:147107882
418 418 a, t dbSNP:780295872
420 420 a, c dbSNP:747332492
423 423 c, t dbSNP:550395617
430 430 a, g dbSNP:769320006
431 431 a, g dbSNP:200860457
441 441 c, t dbSNP:201771506
444 444 c, t dbSNP:149417020
456 456 a, g dbSNP:769471584
460 460 c, g dbSNP:199904970
463 463 a, g dbSNP:762573778
468 468 a, g, t dbSNP:371415976
477 477 a, t dbSNP:200679996
491 491 a, g dbSNP:397517032
494 494 c, t dbSNP:121918712
496 496 a, g dbSNP:781042616
501 501 a, g dbSNP:201497553
508 508 a, g dbSNP:200018073
528 528 a, t dbSNP:769871453
535 535 g, t dbSNP:727503470
567 567 a, g dbSNP:201021249
573 573 a, g dbSNP:201444476
575 575 a, g dbSNP:772339721
597 597 c, t dbSNP:202156059
613 613 c, t dbSNP:775429965
615 615 c, t dbSNP:200078591
617 617 c, t dbSNP:111854391
618 618 a, g dbSNP:201112150
636 636 a, g dbSNP:764165477
648 648 c, t dbSNP:202189494
655 655 c, t dbSNP:777077652
663 663 c, t dbSNP:762125867
674 674 a, t dbSNP:397517033
690 690 a, c dbSNP:200158200
694 694 a, g dbSNP:727503471
704 704 a, g dbSNP:201475375
705 705 c, t dbSNP:147388628
708 708 c, t dbSNP:200511345
730 730 c, g dbSNP:112300506
739 739 c, t dbSNP:755827803
756 756 c, t dbSNP:371269876
757 757 c, t dbSNP:201605956
766 766 c, t dbSNP:191136014
767 767 a, g dbSNP:35974499
773 773 a, g dbSNP:199759998
778 778 a, t dbSNP:200560562
783 783 a, g dbSNP:201943631
784 784 a, g dbSNP:757284158
787 787 a, g dbSNP:764452904
790 790 a, g dbSNP:199822546
792 792 a, g dbSNP:369881419
811 811 c, g, t dbSNP:768667498
813 813 c, t dbSNP:748434255
821 821 c, t dbSNP:200518416
822 822 a, g dbSNP:201323409
824 824 c, t dbSNP:202010361
825 825 a, g dbSNP:139090459
828 828 c, t dbSNP:200912890
829 829 a, g dbSNP:760079636
840 840 c, t dbSNP:767005593
847 847 a, c dbSNP:752190665
848 848 g, t dbSNP:121918710
853 853 a, c dbSNP:760419678
888 888 c, t dbSNP:199770942
889 889 -, agagat dbSNP:727504383
903 903 a, g dbSNP:761512764
904 904 a, g dbSNP:113911127
927 927 c, t dbSNP:192662552
935 935 a, c, g dbSNP:113786548
960 960 a, c, g dbSNP:758280185
964 964 a, g dbSNP:779100123
986 986 c, g dbSNP:201050937
1005 1005 c, t dbSNP:368402450
1014 1014 a, g dbSNP:777805295
1020 1020 a, c dbSNP:7861780
1033 1033 g, t dbSNP:746666082
1034 1034 c, g dbSNP:746047431
1036 1036 c, t dbSNP:760555508
1047 1047 c, t dbSNP:115324990
1056 1056 c, t dbSNP:747584981
1062 1062 c, t dbSNP:769218243
1064 1064 c, t dbSNP:199574997
1081 1081 g, t dbSNP:747644508
1088 1088 a, g dbSNP:200657153
1094 1094 a, g dbSNP:121918711
1098 1098 c, t dbSNP:200358981
1100 1100 a, g dbSNP:762486367
1103 1103 c, g, t dbSNP:557200755
1105 1105 a, g dbSNP:143435050
1111 1111 a, c, t dbSNP:200062984
1113 1113 a, g dbSNP:757399188
1114 1114 c, g dbSNP:146549837
1127 1127 c, t dbSNP:200986584
1132 1132 c, t dbSNP:200595614
1135 1135 c, t dbSNP:387906697
1144 1144 a, g dbSNP:764050602
1158 1158 a, t dbSNP:781386406
1170 1170 a, g dbSNP:753301297
1172 1172 g, t dbSNP:756570466
1173 1173 g, t dbSNP:368928967
1179 1179 c, t dbSNP:201163170
1180 1180 c, t dbSNP:201745016
1209 1209 c, t dbSNP:770604680
1219 1219 a, g dbSNP:778579239
1222 1222 a, g dbSNP:745499424
1239 1239 a, g dbSNP:771962930
1248 1248 a, g dbSNP:775143255
1250 1250 -, c dbSNP:111820381
1253 1253 a, c dbSNP:760666606
1273 1273 a, g dbSNP:768418563
1282 1282 g, t dbSNP:776749573
1283 1283 a, c dbSNP:748073284
1289 1289 a, g dbSNP:556555554
1294 1294 a, g dbSNP:199926741
1304 1304 c, t dbSNP:774565396
1315 1315 a, t dbSNP:759805984
1320 1320 g, t dbSNP:767589799
1328 1328 a, g, t dbSNP:141259922
1330 1330 a, g dbSNP:377194685
1339 1339 a, g dbSNP:730880223
1351 1351 c, t dbSNP:111818778
1354 1354 c, t dbSNP:111426349
1355 1355 a, c, g dbSNP:113605875
1374 1374 a, g dbSNP:144985585
1382 1382 a, g dbSNP:764733540
1384 1384 c, g dbSNP:749879202
1392 1392 a, g dbSNP:200055681
1412 1412 a, g dbSNP:201254457
1414 1414 a, g dbSNP:779531038
1427 1427 c, t dbSNP:369611795
1429 1429 c, g dbSNP:754777682
1432 1432 c, t dbSNP:202041245
1433 1433 g, t dbSNP:781117226
1433 1433 -, t dbSNP:746953792
1438 1438 c, t dbSNP:201753435
1444 1444 c, g dbSNP:769785618
1453 1453 c, t dbSNP:192327847
1459 1459 a, t dbSNP:745898677
1463 1463 a, g dbSNP:994
1476 1476 a, g dbSNP:868
1489 1489 a, t dbSNP:200966435
1507 1507 g, t dbSNP:201855724
1521 1521 c, t dbSNP:200434439
1526 1526 g, t dbSNP:184489732
1527 1527 c, t dbSNP:201350756
1539 1539 a, g dbSNP:767616657
1553 1553 -, c dbSNP:35702937
1594 1594 c, t dbSNP:202238690
1603 1603 c, t dbSNP:200533591
1612 1612 c, t dbSNP:201419046
1613 1613 a, g dbSNP:199609928
1618 1618 a, t dbSNP:200495698
1634 1634 a, t dbSNP:760980107
1651 1651 a, g dbSNP:560210246
1659 1659 c, t dbSNP:201563225
1704 1704 c, t dbSNP:199683401
1718 1718 a, g dbSNP:200804500
1729 1729 a, c dbSNP:528867293
1745 1745 a, g dbSNP:201682869
1746 1746 g, t dbSNP:199861787
1752 1752 a, g dbSNP:200832519
1764 1764 a, t dbSNP:368380699
1765 1765 c, t dbSNP:764209146
1767 1767 a, g dbSNP:145692006
1778 1778 c, t dbSNP:200019371
1779 1779 c, t dbSNP:200786932
1782 1782 c, t dbSNP:201903995
1813 1813 a, t dbSNP:750730238
1823 1823 c, g dbSNP:200063976
1836 1836 c, g dbSNP:201260283
1848 1848 c, t dbSNP:202012098
1863 1863 g, t dbSNP:200245567
1877 1877 a, g dbSNP:201142879
1880 1880 -, t dbSNP:568494416
1880 1880 a, g dbSNP:202133538
1889 1889 g, t dbSNP:200294552
1892 1892 c, g dbSNP:531460959
1909 1909 c, t dbSNP:201269197
1915 1915 -, tctta dbSNP:777186940
1920 1920 a, t dbSNP:199521592
1927 1927 c, t dbSNP:200514984
1930 1930 a, g dbSNP:11568807
1945 1945 c, t dbSNP:199578935
1959 1959 a, g dbSNP:200511595
1962 1962 a, g dbSNP:201606447
1966 1966 a, g dbSNP:559337318
1969 1969 c, g dbSNP:199765042
1973 1973 c, t dbSNP:11568808
1981 1981 a, g dbSNP:201687617
1986 1986 c, g dbSNP:754640242
1998 1998 -, tt dbSNP:750491076
2036 2036 a, c dbSNP:199867951
2044 2044 a, g dbSNP:201205567
2119 2119 a, g dbSNP:780634517
2121 2121 a, g dbSNP:201984381
2135 2135 a, g dbSNP:199993828
2163 2163 c, t dbSNP:200926268
2185 2185 a, g dbSNP:202158467
2196 2196 a, g dbSNP:200428927
2203 2203 a, c dbSNP:201076760
2238 2238 a, c dbSNP:201996934
2250 2250 g, t dbSNP:200224469
2256 2256 c, t dbSNP:201615730
2284 2284 a, g dbSNP:199734350
2291 2291 a, g dbSNP:334348
2297 2297 a, g dbSNP:201052504
2299 2299 a, g dbSNP:199549381
2300 2300 a, g dbSNP:200679214
2306 2306 c, t dbSNP:36049024
2320 2320 c, t dbSNP:201990134
2328 2328 g, t dbSNP:34325659
2333 2333 c, t dbSNP:199584415
2356 2356 a, g dbSNP:189593120
2374 2374 c, g dbSNP:200755777
2380 2380 c, g dbSNP:756852117
2385 2385 a, g dbSNP:35870119
2411 2411 a, t dbSNP:35607843
2413 2413 c, t dbSNP:201910377
2441 2441 a, g dbSNP:200005909
2443 2443 g, t dbSNP:201098935
2453 2453 g, t dbSNP:201701125
2456 2456 c, t dbSNP:11568809
2470 2470 a, g dbSNP:201191454
2473 2473 a, g dbSNP:778564621
2484 2484 a, g dbSNP:539294464
2495 2495 c, t dbSNP:202224779
2499 2499 a, g dbSNP:559316578
2510 2510 c, g dbSNP:199978072
2518 2518 c, t dbSNP:201110333
2561 2561 c, t dbSNP:141078676
2578 2578 c, t dbSNP:10988732
2586 2586 a, g dbSNP:193056376
2589 2589 c, t dbSNP:200376574
2590 2590 a, g dbSNP:184564501
2613 2613 c, g dbSNP:201746454
2614 2614 a, g dbSNP:200186059
2639 2639 c, t dbSNP:201621825
2646 2646 c, t dbSNP:199740407
2647 2647 a, g dbSNP:200689459
2651 2651 a, g dbSNP:201519485
2666 2666 c, g, t dbSNP:150247576
2667 2667 a, g dbSNP:200765185
2675 2675 c, t dbSNP:541995278
2676 2676 c, g, t dbSNP:189032587
2677 2677 c, t dbSNP:774659140
2695 2695 g, t dbSNP:199956399
2700 2700 c, g, t dbSNP:200739404
2723 2723 c, g dbSNP:201894361
2727 2727 a, g dbSNP:138860379
2731 2731 c, t dbSNP:564868044
2739 2739 a, g dbSNP:200076723
2749 2749 a, g dbSNP:201116349
2750 2750 c, t dbSNP:11568810
2753 2753 a, g dbSNP:567642330
2771 2771 c, t dbSNP:530171542
2772 2772 g, t dbSNP:199891042
2776 2776 a, g dbSNP:200970226
2783 2783 c, g dbSNP:201863088
2785 2785 a, g dbSNP:200278937
2812 2812 c, t dbSNP:201453348
2817 2817 c, t dbSNP:201952413
2819 2819 c, t dbSNP:200562457
2835 2835 c, g dbSNP:11568811
2854 2854 a, t dbSNP:199588065
2858 2858 c, t dbSNP:200560836
2862 2862 c, t dbSNP:760928585
2863 2863 a, g dbSNP:769029753
2916 2916 g, t dbSNP:570039754
2922 2922 a, g dbSNP:11568812
2936 2936 a, g dbSNP:559280038
2948 2948 c, t dbSNP:199733000
2949 2949 g, t dbSNP:776540727
2974 2974 a, g dbSNP:200669525
2979 2979 a, g dbSNP:79410528
2981 2981 a, g dbSNP:199522012
2989 2989 c, t dbSNP:200943776
3010 3010 a, g dbSNP:201500025
3019 3019 c, t dbSNP:200036408
3021 3021 a, g dbSNP:200791684
3047 3047 a, g dbSNP:201604963
3066 3066 c, t dbSNP:200082162
3093 3093 -, ta dbSNP:780605360
3095 3095 c, t dbSNP:201101156
3104 3104 c, t dbSNP:181403208
3117 3117 a, g dbSNP:200197062
3155 3155 a, g dbSNP:201222590
3158 3158 c, t dbSNP:202128625
3159 3159 a, g dbSNP:200296344
3166 3166 a, c dbSNP:183812806
3179 3179 a, c dbSNP:201191009
3185 3185 a, g dbSNP:200566464
3205 3205 c, t dbSNP:138248864
3206 3206 a, g dbSNP:199580278
3211 3211 a, g dbSNP:200656974
3232 3232 a, g dbSNP:201607717
3275 3275 a, g dbSNP:199765790
3276 3276 c, g dbSNP:200570178
3285 3285 g, t dbSNP:201434094
3348 3348 a, t dbSNP:199811787
3367 3367 c, t dbSNP:201307737
3395 3395 g, t dbSNP:201829833
3412 3412 g, t dbSNP:144216869
3450 3450 a, g dbSNP:527618646
3477 3477 a, t dbSNP:540978964
3488 3488 -, gtt dbSNP:75796733
3488 3488 g, t dbSNP:200898127
3489 3489 g, t dbSNP:112113922
3493 3493 g, t dbSNP:148063684
3497 3497 a, g, t dbSNP:201152885
3499 3499 -, t dbSNP:376556150
3499 3499 g, t dbSNP:199545273
3500 3500 g, t dbSNP:202187266
3500 3500 -, t dbSNP:200529894
3501 3501 g, t dbSNP:200204084
3502 3502 g, t dbSNP:201780012
3503 3503 -, tg dbSNP:541820908
3503 3503 g, t dbSNP:200867114
3504 3504 -, g, gt dbSNP:61566226
3505 3505 g, t dbSNP:201738100
3506 3506 g, t dbSNP:199659996
3507 3507 g, t dbSNP:532530728
3510 3510 -, g dbSNP:36064078
3510 3510 g, t dbSNP:7871490
3513 3513 g, t dbSNP:201054018
3519 3519 -, ttt dbSNP:199589877
3519 3519 g, t dbSNP:60885995
3524 3524 g, t dbSNP:181680115
3553 3553 c, t dbSNP:200675329
3561 3561 a, g dbSNP:201153037
3586 3586 -, a dbSNP:373576679
3641 3641 a, g dbSNP:754588954
3653 3653 g, t dbSNP:552650250
3660 3660 c, t dbSNP:199645690
3669 3669 g, t dbSNP:200653031
3681 3681 a, g dbSNP:202068970
3800 3800 a, g dbSNP:77810552
3817 3817 c, t dbSNP:200722893
3818 3818 a, g dbSNP:11568813
3822 3822 g, t dbSNP:140497381
3833 3833 a, g dbSNP:185811148
3858 3858 g, t dbSNP:201140077
3880 3880 a, t dbSNP:202106034
3889 3889 -, gaaa dbSNP:747408434
3927 3927 c, t dbSNP:200032389
3928 3928 c, t dbSNP:200985953
3929 3929 a, g dbSNP:202239214
3943 3943 a, c dbSNP:200378819
3963 3963 a, t dbSNP:200553684
3980 3980 c, t dbSNP:537279747
3982 3982 a, g dbSNP:201156487
3995 3995 c, t dbSNP:201719827
3997 3997 a, c dbSNP:11544423
4025 4025 c, g dbSNP:200240411
4027 4027 a, g dbSNP:201765733
4034 4034 g, t dbSNP:147373120
4043 4043 a, t dbSNP:199685230
4045 4045 c, t dbSNP:555815837
4052 4052 a, c dbSNP:17724567
4053 4053 c, t dbSNP:201410594
4059 4059 a, g dbSNP:199515707
4080 4080 a, g dbSNP:749188476
4092 4092 g, t dbSNP:145043837
4101 4101 a, g dbSNP:201761492
4102 4102 a, g dbSNP:199959704
4103 4103 a, g dbSNP:200552727
4105 4105 a, g dbSNP:202073426
4110 4110 a, g dbSNP:76392135
4114 4114 c, t dbSNP:201264579
4139 4139 c, t dbSNP:202010937
4166 4166 a, g dbSNP:199878100
4167 4167 c, g dbSNP:201021066
4198 4198 a, g dbSNP:201846922
4206 4206 c, t dbSNP:200274678
4207 4207 a, g dbSNP:334349
4225 4225 a, g dbSNP:202139828
4240 4240 a, g dbSNP:200520116
4248 4248 a, g dbSNP:201591510
4251 4251 c, t dbSNP:199594054
4253 4253 a, g dbSNP:200238696
4262 4262 c, t dbSNP:201552761
4263 4263 a, g dbSNP:199736646
4284 4284 c, t dbSNP:200813968
4309 4309 g, t dbSNP:201689327
4312 4312 a, g dbSNP:199520869
4324 4324 g, t dbSNP:144871415
4329 4329 c, t dbSNP:200836217
4343 4343 a, t dbSNP:202035846
4363 4363 c, t dbSNP:200010917
4384 4384 c, t dbSNP:200777095
4385 4385 a, g dbSNP:28427103
4412 4412 a, g dbSNP:773581822
4431 4431 a, g dbSNP:529885530
4462 4462 a, g dbSNP:201599459
4466 4466 a, g dbSNP:200138586
4490 4490 a, g dbSNP:201249841
4491 4491 a, c dbSNP:202000313
4501 4501 a, g dbSNP:191007659
4510 4510 a, g dbSNP:543672032
4512 4512 a, g dbSNP:200225987
4516 4516 a, g dbSNP:201277448
4522 4522 a, c, g dbSNP:202129409
4530 4530 c, g dbSNP:773179495
4536 4536 c, g, t dbSNP:200301959
4537 4537 c, t dbSNP:201273317
4548 4548 a, g dbSNP:199540214
4552 4552 a, g dbSNP:11544424
4557 4557 c, t dbSNP:200525939
4598 4598 a, c dbSNP:201595773
4599 4599 c, t dbSNP:148797981
4613 4613 c, t dbSNP:200734120
4623 4623 g, t dbSNP:201601841
4625 4625 a, g dbSNP:142454519
4626 4626 a, g dbSNP:766905645
4628 4628 a, g dbSNP:199752579
4630 4630 a, c dbSNP:200620396
4632 4632 a, g dbSNP:3739798
4634 4634 a, g dbSNP:199886589
4642 4642 c, t dbSNP:201191549
4644 4644 c, t dbSNP:151310060
4652 4652 c, g dbSNP:202040220
4657 4657 c, t dbSNP:199982490
4663 4663 a, c dbSNP:201114226
4668 4668 c, t dbSNP:117440593
4669 4669 c, t dbSNP:78385793
4684 4684 c, t dbSNP:201094276
4693 4693 c, g dbSNP:420549
4697 4697 a, g dbSNP:755731287
4703 4703 a, g, t dbSNP:200228516
4705 4705 a, g dbSNP:140654961
4713 4713 a, g dbSNP:202218587
4721 4721 a, g dbSNP:200374520
4724 4724 c, g dbSNP:201113438
4759 4759 c, t dbSNP:199531451
4768 4768 a, g dbSNP:200676329
4773 4773 c, t dbSNP:145719397
4774 4774 c, t dbSNP:199642245
4775 4775 a, g dbSNP:200742860
4783 4783 a, g dbSNP:201896896
4789 4789 g, t dbSNP:200080374
4797 4797 a, g dbSNP:200724388
4806 4806 g, t dbSNP:201706420
4833 4833 a, g dbSNP:199858917
4835 4835 g, t dbSNP:201143384
4836 4836 -, a dbSNP:78078491
4855 4855 c, t dbSNP:146582850
4865 4865 c, t dbSNP:199969402
4874 4874 a, g dbSNP:201094409
4875 4875 g, t dbSNP:568480971
4888 4888 a, c dbSNP:571974570
4889 4889 c, g, t dbSNP:201952588
4901 4901 g, t dbSNP:534357285
4910 4910 g, t dbSNP:200562618
4944 4944 a, g dbSNP:554828293
4950 4950 c, t dbSNP:201157110
4951 4951 a, c dbSNP:201723845
4969 4969 a, g dbSNP:200245074
4972 4972 c, t dbSNP:201287805
5007 5007 a, g dbSNP:574691862
5020 5020 a, g dbSNP:564200861
5021 5021 a, t dbSNP:199726281
5032 5032 -, a dbSNP:781486193
5062 5062 a, g dbSNP:757835312
5105 5105 a, g dbSNP:200670357
5108 5108 g, t dbSNP:201522923
5111 5111 a, g dbSNP:563433922
5112 5112 a, g dbSNP:535550887
5115 5115 a, t dbSNP:181994273
5120 5120 a, g dbSNP:200775937
5138 5138 g, t dbSNP:201764616
5142 5142 c, t dbSNP:199961896
5143 5143 a, g dbSNP:559623340
5166 5166 a, g dbSNP:200535063
5186 5186 c, t dbSNP:201887512
5187 5187 a, g dbSNP:200173366
5194 5194 c, t dbSNP:377612306
5197 5197 c, t dbSNP:201101442
5205 5205 a, g dbSNP:141277814
5223 5223 a, g dbSNP:199803452
5237 5237 c, t dbSNP:186157987
5242 5242 a, c dbSNP:201848660
5244 5244 a, g dbSNP:768088879
5283 5283 a, g dbSNP:200275772
5285 5285 c, t dbSNP:190633391
5286 5286 a, g dbSNP:531799828
5340 5340 c, t dbSNP:200772657
5341 5341 c, t dbSNP:201957037
5362 5362 a, g dbSNP:200567981
5386 5386 c, g dbSNP:114704997
5387 5387 a, g dbSNP:199582297
5400 5400 g, t dbSNP:200241838
5426 5426 c, g dbSNP:550863468
5434 5434 a, g dbSNP:201535475
5437 5437 a, g dbSNP:199718989
5439 5439 c, g dbSNP:200721028
5447 5447 a, t dbSNP:41283640
5498 5498 a, g dbSNP:199511095
5502 5502 c, t dbSNP:200932500
5517 5517 a, t dbSNP:201831473
5522 5522 a, g dbSNP:200013714
5528 5528 g, t dbSNP:200780252
5537 5537 a, g dbSNP:201600236
5543 5543 c, t dbSNP:200142252
5554 5554 g, t dbSNP:570685518
5570 5570 c, g dbSNP:201105741
5596 5596 a, g dbSNP:202187992
5609 5609 a, g dbSNP:200206515
5611 5611 a, g dbSNP:201385076
5614 5614 g, t dbSNP:202104135
5620 5620 a, t dbSNP:550614032
5627 5627 c, t dbSNP:200270666
5633 5633 g, t dbSNP:201343315
5643 5643 a, t dbSNP:182830158
5685 5685 c, t dbSNP:200414044
5686 5686 -, ttatg dbSNP:747830813
5700 5700 a, g dbSNP:201453868
5702 5702 c, t dbSNP:199650257
5707 5707 c, g, t dbSNP:41283642
5718 5718 c, t dbSNP:202070537
5736 5736 a, g dbSNP:199756594
5738 5738 c, t dbSNP:200621336
5762 5762 c, t dbSNP:554310366
5763 5763 a, g dbSNP:201446431
5773 5773 a, g dbSNP:199892683
5774 5774 c, t dbSNP:201313404
5779 5779 c, t dbSNP:201836319
5782 5782 a, g dbSNP:200033182
5786 5786 a, g dbSNP:557308076
5787 5787 c, t dbSNP:577095630
5795 5795 a, g dbSNP:200967869

Target ORF information:

RefSeq Version XM_011518950
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens transforming growth factor, beta receptor 1 (TGFBR1), transcript variant X4, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011518950

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
ATGTGTATAG CTGAAATTGA CTTAATTCCT CGAGATAGGC CGTTTGTATG TGCACCCTCT 
TCAAAAACTG GGTCTGTGAC TACAACATAT TGCTGCAATC AGGACCATTG CAATAAAATA
GAACTTCCAA CTACTGGTTT ACCATTGCTT GTTCAGAGAA CAATTGCGAG AACTATTGTG
TTACAAGAAA GCATTGGCAA AGGTCGATTT GGAGAAGTTT GGAGAGGAAA GTGGCGGGGA
GAAGAAGTTG CTGTTAAGAT ATTCTCCTCT AGAGAAGAAC GTTCGTGGTT CCGTGAGGCA
GAGATTTATC AAACTGTAAT GTTACGTCAT GAAAACATCC TGGGATTTAT AGCAGCAGAC
AATAAAGACA ATGGTACTTG GACTCAGCTC TGGTTGGTGT CAGATTATCA TGAGCATGGA
TCCCTTTTTG ATTACTTAAA CAGATACACA GTTACTGTGG AAGGAATGAT AAAACTTGCT
CTGTCCACGG CGAGCGGTCT TGCCCATCTT CACATGGAGA TTGTTGGTAC CCAAGGAAAG
CCAGCCATTG CTCATAGAGA TTTGAAATCA AAGAATATCT TGGTAAAGAA GAATGGAACT
TGCTGTATTG CAGACTTAGG ACTGGCAGTA AGACATGATT CAGCCACAGA TACCATTGAT
ATTGCTCCAA ACCACAGAGT GGGAACAAAA AGGTACATGG CCCCTGAAGT TCTCGATGAT
TCCATAAATA TGAAACATTT TGAATCCTTC AAACGTGCTG ACATCTATGC AATGGGCTTA
GTATTCTGGG AAATTGCTCG ACGATGTTCC ATTGGTGGAA TTCATGAAGA TTACCAACTG
CCTTATTATG ATCTTGTACC TTCTGACCCA TCAGTTGAAG AAATGAGAAA AGTTGTTTGT
GAACAGAAGT TAAGGCCAAA TATCCCAAAC AGATGGCAGA GCTGTGAAGC CTTGAGAGTA
ATGGCTAAAA TTATGAGAGA ATGTTGGTAT GCCAATGGAG CAGCTAGGCT TACAGCATTG
CGGATTAAGA AAACATTATC GCAACTCAGT CAACAGGAAG GCATCAAAAT GTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu16616
Accession Version NM_001130916.2 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1281bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector Document: User manual_GenEZ ORF Clone Products.pdf (pdf)
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags Document: MSDS_GenEZ ORF Clone Products.pdf (pdf)
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 21-MAY-2015
Organism Homo sapiens (human)
Product TGF-beta receptor type-1 isoform 2 precursor
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK302059.1, BC071181.1 and AJ619019.2. On May 4, 2015 this sequence version replaced gi:195963411. Summary: The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]. Transcript Variant: This variant (2) lacks an in-frame exon in the 5' coding region, compared to variant 3. The encoded isoform (2) is shorter than isoform 3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC071181.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
ATGGAGGCGG CGGTCGCTGC TCCGCGTCCC CGGCTGCTCC TCCTCGTGCT GGCGGCGGCG 
GCGGCGGCGG CGGCGGCGCT GCTCCCGGGG GCGACGGCGT TACAGTGTTT CTGCCACCTC
TGTACAAAAG ACAATTTTAC TTGTGTGACA GATGGGCTCT GCTTTGTCTC TGTCACAGAG
ACCACAGACA AAGTTATACA CAACAGCATG TGTATAGCTG AAATTGACTT AATTCCTCGA
GATAGGCCGT TTGTATGTGC ACCCTCTTCA AAAACTGGGT CTGTGACTAC AACATATTGC
TGCAATCAGG ACCATTGCAA TAAAATAGAA CTTCCAACTA CTGGTTTACC ATTGCTTGTT
CAGAGAACAA TTGCGAGAAC TATTGTGTTA CAAGAAAGCA TTGGCAAAGG TCGATTTGGA
GAAGTTTGGA GAGGAAAGTG GCGGGGAGAA GAAGTTGCTG TTAAGATATT CTCCTCTAGA
GAAGAACGTT CGTGGTTCCG TGAGGCAGAG ATTTATCAAA CTGTAATGTT ACGTCATGAA
AACATCCTGG GATTTATAGC AGCAGACAAT AAAGACAATG GTACTTGGAC TCAGCTCTGG
TTGGTGTCAG ATTATCATGA GCATGGATCC CTTTTTGATT ACTTAAACAG ATACACAGTT
ACTGTGGAAG GAATGATAAA ACTTGCTCTG TCCACGGCGA GCGGTCTTGC CCATCTTCAC
ATGGAGATTG TTGGTACCCA AGGAAAGCCA GCCATTGCTC ATAGAGATTT GAAATCAAAG
AATATCTTGG TAAAGAAGAA TGGAACTTGC TGTATTGCAG ACTTAGGACT GGCAGTAAGA
CATGATTCAG CCACAGATAC CATTGATATT GCTCCAAACC ACAGAGTGGG AACAAAAAGG
TACATGGCCC CTGAAGTTCT CGATGATTCC ATAAATATGA AACATTTTGA ATCCTTCAAA
CGTGCTGACA TCTATGCAAT GGGCTTAGTA TTCTGGGAAA TTGCTCGACG ATGTTCCATT
GGTGGAATTC ATGAAGATTA CCAACTGCCT TATTATGATC TTGTACCTTC TGACCCATCA
GTTGAAGAAA TGAGAAAAGT TGTTTGTGAA CAGAAGTTAA GGCCAAATAT CCCAAACAGA
TGGCAGAGCT GTGAAGCCTT GAGAGTAATG GCTAAAATTA TGAGAGAATG TTGGTATGCC
AATGGAGCAG CTAGGCTTAC AGCATTGCGG ATTAAGAAAA CATTATCGCA ACTCAGTCAA
CAGGAAGGCA TCAAAATGTA A
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_001124388.1
CDS118..1398
Misc Feature(1)64..66(+)
Misc Feature(2)220..459(+)
Misc Feature(3)457..495(+)
Misc Feature(4)499..1356(+)
Misc Feature(5)511..1374(+)
Misc Feature(6)517..1017(+)
Misc Feature(7)517..939(+)
Misc Feature(8)529..1017(+)
Misc Feature(9)610..687(+)
Misc Feature(10)934..1017(+)
Exon (1)1..214
Gene:TGFBR1
Gene Synonym:
Exon (2)215..460
Gene:TGFBR1
Gene Synonym:
Exon (3)461..691
Gene:TGFBR1
Gene Synonym:
Exon (4)692..859
Gene:TGFBR1
Gene Synonym:
Exon (5)860..1016
Gene:TGFBR1
Gene Synonym:
Exon (6)1017..1141
Gene:TGFBR1
Gene Synonym:
Exon (7)1142..1272
Gene:TGFBR1
Gene Synonym:
Exon (8)1273..6285
Gene:TGFBR1
Gene Synonym:
Translation
Position Chain Variation Link

Target ORF information:

RefSeq Version NM_001130916
Organism Homo sapiens (human)
Definition Homo sapiens transforming growth factor, beta receptor 1 (TGFBR1), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001130916

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
ATGGAGGCGG CGGTCGCTGC TCCGCGTCCC CGGCTGCTCC TCCTCGTGCT GGCGGCGGCG 
GCGGCGGCGG CGGCGGCGCT GCTCCCGGGG GCGACGGCGT TACAGTGTTT CTGCCACCTC
TGTACAAAAG ACAATTTTAC TTGTGTGACA GATGGGCTCT GCTTTGTCTC TGTCACAGAG
ACCACAGACA AAGTTATACA CAACAGCATG TGTATAGCTG AAATTGACTT AATTCCTCGA
GATAGGCCGT TTGTATGTGC ACCCTCTTCA AAAACTGGGT CTGTGACTAC AACATATTGC
TGCAATCAGG ACCATTGCAA TAAAATAGAA CTTCCAACTA CTGGTTTACC ATTGCTTGTT
CAGAGAACAA TTGCGAGAAC TATTGTGTTA CAAGAAAGCA TTGGCAAAGG TCGATTTGGA
GAAGTTTGGA GAGGAAAGTG GCGGGGAGAA GAAGTTGCTG TTAAGATATT CTCCTCTAGA
GAAGAACGTT CGTGGTTCCG TGAGGCAGAG ATTTATCAAA CTGTAATGTT ACGTCATGAA
AACATCCTGG GATTTATAGC AGCAGACAAT AAAGACAATG GTACTTGGAC TCAGCTCTGG
TTGGTGTCAG ATTATCATGA GCATGGATCC CTTTTTGATT ACTTAAACAG ATACACAGTT
ACTGTGGAAG GAATGATAAA ACTTGCTCTG TCCACGGCGA GCGGTCTTGC CCATCTTCAC
ATGGAGATTG TTGGTACCCA AGGAAAGCCA GCCATTGCTC ATAGAGATTT GAAATCAAAG
AATATCTTGG TAAAGAAGAA TGGAACTTGC TGTATTGCAG ACTTAGGACT GGCAGTAAGA
CATGATTCAG CCACAGATAC CATTGATATT GCTCCAAACC ACAGAGTGGG AACAAAAAGG
TACATGGCCC CTGAAGTTCT CGATGATTCC ATAAATATGA AACATTTTGA ATCCTTCAAA
CGTGCTGACA TCTATGCAAT GGGCTTAGTA TTCTGGGAAA TTGCTCGACG ATGTTCCATT
GGTGGAATTC ATGAAGATTA CCAACTGCCT TATTATGATC TTGTACCTTC TGACCCATCA
GTTGAAGAAA TGAGAAAAGT TGTTTGTGAA CAGAAGTTAA GGCCAAATAT CCCAAACAGA
TGGCAGAGCT GTGAAGCCTT GAGAGTAATG GCTAAAATTA TGAGAGAATG TTGGTATGCC
AATGGAGCAG CTAGGCTTAC AGCATTGCGG ATTAAGAAAA CATTATCGCA ACTCAGTCAA
CAGGAAGGCA TCAAAATGTA A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu17991
Accession Version NM_004612.3 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1512bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector Document: User manual_GenEZ ORF Clone Products.pdf (pdf)
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags Document: MSDS_GenEZ ORF Clone Products.pdf (pdf)
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 21-MAY-2015
Organism Homo sapiens (human)
Product TGF-beta receptor type-1 isoform 1 precursor
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK302059.1, L11695.1 and AJ619019.2. This sequence is a reference standard in the RefSeqGene project. On May 4, 2015 this sequence version replaced gi:66346739. Summary: The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]. Transcript Variant: This variant (1) uses an alternate in-frame splice site in the 5' coding region, compared to variant 3. The encoded isoform (1) is shorter than isoform 3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: L11695.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
ATGGAGGCGG CGGTCGCTGC TCCGCGTCCC CGGCTGCTCC TCCTCGTGCT GGCGGCGGCG 
GCGGCGGCGG CGGCGGCGCT GCTCCCGGGG GCGACGGCGT TACAGTGTTT CTGCCACCTC
TGTACAAAAG ACAATTTTAC TTGTGTGACA GATGGGCTCT GCTTTGTCTC TGTCACAGAG
ACCACAGACA AAGTTATACA CAACAGCATG TGTATAGCTG AAATTGACTT AATTCCTCGA
GATAGGCCGT TTGTATGTGC ACCCTCTTCA AAAACTGGGT CTGTGACTAC AACATATTGC
TGCAATCAGG ACCATTGCAA TAAAATAGAA CTTCCAACTA CTGTAAAGTC ATCACCTGGC
CTTGGTCCTG TGGAACTGGC AGCTGTCATT GCTGGACCAG TGTGCTTCGT CTGCATCTCA
CTCATGTTGA TGGTCTATAT CTGCCACAAC CGCACTGTCA TTCACCATCG AGTGCCAAAT
GAAGAGGACC CTTCATTAGA TCGCCCTTTT ATTTCAGAGG GTACTACGTT GAAAGACTTA
ATTTATGATA TGACAACGTC AGGTTCTGGC TCAGGTTTAC CATTGCTTGT TCAGAGAACA
ATTGCGAGAA CTATTGTGTT ACAAGAAAGC ATTGGCAAAG GTCGATTTGG AGAAGTTTGG
AGAGGAAAGT GGCGGGGAGA AGAAGTTGCT GTTAAGATAT TCTCCTCTAG AGAAGAACGT
TCGTGGTTCC GTGAGGCAGA GATTTATCAA ACTGTAATGT TACGTCATGA AAACATCCTG
GGATTTATAG CAGCAGACAA TAAAGACAAT GGTACTTGGA CTCAGCTCTG GTTGGTGTCA
GATTATCATG AGCATGGATC CCTTTTTGAT TACTTAAACA GATACACAGT TACTGTGGAA
GGAATGATAA AACTTGCTCT GTCCACGGCG AGCGGTCTTG CCCATCTTCA CATGGAGATT
GTTGGTACCC AAGGAAAGCC AGCCATTGCT CATAGAGATT TGAAATCAAA GAATATCTTG
GTAAAGAAGA ATGGAACTTG CTGTATTGCA GACTTAGGAC TGGCAGTAAG ACATGATTCA
GCCACAGATA CCATTGATAT TGCTCCAAAC CACAGAGTGG GAACAAAAAG GTACATGGCC
CCTGAAGTTC TCGATGATTC CATAAATATG AAACATTTTG AATCCTTCAA ACGTGCTGAC
ATCTATGCAA TGGGCTTAGT ATTCTGGGAA ATTGCTCGAC GATGTTCCAT TGGTGGAATT
CATGAAGATT ACCAACTGCC TTATTATGAT CTTGTACCTT CTGACCCATC AGTTGAAGAA
ATGAGAAAAG TTGTTTGTGA ACAGAAGTTA AGGCCAAATA TCCCAAACAG ATGGCAGAGC
TGTGAAGCCT TGAGAGTAAT GGCTAAAATT ATGAGAGAAT GTTGGTATGC CAATGGAGCA
GCTAGGCTTA CAGCATTGCG GATTAAGAAA ACATTATCGC AACTCAGTCA ACAGGAAGGC
ATCAAAATGT AA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_004603.1
CDS118..1629
Misc Feature(1)64..66(+)
Misc Feature(2)220..459(+)
Misc Feature(3)631..633(+)
Misc Feature(4)640..726(+)
Misc Feature(5)643..645(+)
Misc Feature(6)730..1587(+)
Misc Feature(7)742..1605(+)
Misc Feature(8)748..1248(+)
Misc Feature(9)748..1170(+)
Misc Feature(10)760..1248(+)
Misc Feature(11)841..918(+)
Misc Feature(12)1165..1248(+)
Exon (1)1..214
Gene:TGFBR1
Gene Synonym:
Exon (2)215..460
Gene:TGFBR1
Gene Synonym:
Exon (3)461..691
Gene:TGFBR1
Gene Synonym:
Exon (4)692..922
Gene:TGFBR1
Gene Synonym:
Exon (5)923..1090
Gene:TGFBR1
Gene Synonym:
Exon (6)1091..1247
Gene:TGFBR1
Gene Synonym:
Exon (7)1248..1372
Gene:TGFBR1
Gene Synonym:
Exon (8)1373..1503
Gene:TGFBR1
Gene Synonym:
Exon (9)1504..6516
Gene:TGFBR1
Gene Synonym:
Translation
Position Chain Variation Link

Target ORF information:

RefSeq Version NM_004612
Organism Homo sapiens (human)
Definition Homo sapiens transforming growth factor, beta receptor 1 (TGFBR1), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_004612

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
ATGGAGGCGG CGGTCGCTGC TCCGCGTCCC CGGCTGCTCC TCCTCGTGCT GGCGGCGGCG 
GCGGCGGCGG CGGCGGCGCT GCTCCCGGGG GCGACGGCGT TACAGTGTTT CTGCCACCTC
TGTACAAAAG ACAATTTTAC TTGTGTGACA GATGGGCTCT GCTTTGTCTC TGTCACAGAG
ACCACAGACA AAGTTATACA CAACAGCATG TGTATAGCTG AAATTGACTT AATTCCTCGA
GATAGGCCGT TTGTATGTGC ACCCTCTTCA AAAACTGGGT CTGTGACTAC AACATATTGC
TGCAATCAGG ACCATTGCAA TAAAATAGAA CTTCCAACTA CTGTAAAGTC ATCACCTGGC
CTTGGTCCTG TGGAACTGGC AGCTGTCATT GCTGGACCAG TGTGCTTCGT CTGCATCTCA
CTCATGTTGA TGGTCTATAT CTGCCACAAC CGCACTGTCA TTCACCATCG AGTGCCAAAT
GAAGAGGACC CTTCATTAGA TCGCCCTTTT ATTTCAGAGG GTACTACGTT GAAAGACTTA
ATTTATGATA TGACAACGTC AGGTTCTGGC TCAGGTTTAC CATTGCTTGT TCAGAGAACA
ATTGCGAGAA CTATTGTGTT ACAAGAAAGC ATTGGCAAAG GTCGATTTGG AGAAGTTTGG
AGAGGAAAGT GGCGGGGAGA AGAAGTTGCT GTTAAGATAT TCTCCTCTAG AGAAGAACGT
TCGTGGTTCC GTGAGGCAGA GATTTATCAA ACTGTAATGT TACGTCATGA AAACATCCTG
GGATTTATAG CAGCAGACAA TAAAGACAAT GGTACTTGGA CTCAGCTCTG GTTGGTGTCA
GATTATCATG AGCATGGATC CCTTTTTGAT TACTTAAACA GATACACAGT TACTGTGGAA
GGAATGATAA AACTTGCTCT GTCCACGGCG AGCGGTCTTG CCCATCTTCA CATGGAGATT
GTTGGTACCC AAGGAAAGCC AGCCATTGCT CATAGAGATT TGAAATCAAA GAATATCTTG
GTAAAGAAGA ATGGAACTTG CTGTATTGCA GACTTAGGAC TGGCAGTAAG ACATGATTCA
GCCACAGATA CCATTGATAT TGCTCCAAAC CACAGAGTGG GAACAAAAAG GTACATGGCC
CCTGAAGTTC TCGATGATTC CATAAATATG AAACATTTTG AATCCTTCAA ACGTGCTGAC
ATCTATGCAA TGGGCTTAGT ATTCTGGGAA ATTGCTCGAC GATGTTCCAT TGGTGGAATT
CATGAAGATT ACCAACTGCC TTATTATGAT CTTGTACCTT CTGACCCATC AGTTGAAGAA
ATGAGAAAAG TTGTTTGTGA ACAGAAGTTA AGGCCAAATA TCCCAAACAG ATGGCAGAGC
TGTGAAGCCT TGAGAGTAAT GGCTAAAATT ATGAGAGAAT GTTGGTATGC CAATGGAGCA
GCTAGGCTTA CAGCATTGCG GATTAAGAAA ACATTATCGC AACTCAGTCA ACAGGAAGGC
ATCAAAATGT AA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu43465
Accession Version NM_001306210.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1524bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector Document: User manual_GenEZ ORF Clone Products.pdf (pdf)
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags Document: MSDS_GenEZ ORF Clone Products.pdf (pdf)
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 21-MAY-2015
Organism Homo sapiens (human)
Product TGF-beta receptor type-1 isoform 3 precursor
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK302059.1 and AJ619019.2. On May 4, 2015 this sequence version replaced gi:530391448. Summary: The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]. Transcript Variant: This variant (3) represents the longest transcript and encodes the longest isoform (3). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AJ619019.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
ATGGAGGCGG CGGTCGCTGC TCCGCGTCCC CGGCTGCTCC TCCTCGTGCT GGCGGCGGCG 
GCGGCGGCGG CGGCGGCGCT GCTCCCGGGG GCGACGGCGT TACAGTGTTT CTGCCACCTC
TGTACAAAAG ACAATTTTAC TTGTGTGACA GATGGGCTCT GCTTTGTCTC TGTCACAGAG
ACCACAGACA AAGTTATACA CAACAGCATG TGTATAGCTG AAATTGACTT AATTCCTCGA
GATAGGCCGT TTGTATGTGC ACCCTCTTCA AAAACTGGGT CTGTGACTAC AACATATTGC
TGCAATCAGG ACCATTGCAA TAAAATAGAA CTTCCAACTA CTGGCCCTTT TTCAGTAAAG
TCATCACCTG GCCTTGGTCC TGTGGAACTG GCAGCTGTCA TTGCTGGACC AGTGTGCTTC
GTCTGCATCT CACTCATGTT GATGGTCTAT ATCTGCCACA ACCGCACTGT CATTCACCAT
CGAGTGCCAA ATGAAGAGGA CCCTTCATTA GATCGCCCTT TTATTTCAGA GGGTACTACG
TTGAAAGACT TAATTTATGA TATGACAACG TCAGGTTCTG GCTCAGGTTT ACCATTGCTT
GTTCAGAGAA CAATTGCGAG AACTATTGTG TTACAAGAAA GCATTGGCAA AGGTCGATTT
GGAGAAGTTT GGAGAGGAAA GTGGCGGGGA GAAGAAGTTG CTGTTAAGAT ATTCTCCTCT
AGAGAAGAAC GTTCGTGGTT CCGTGAGGCA GAGATTTATC AAACTGTAAT GTTACGTCAT
GAAAACATCC TGGGATTTAT AGCAGCAGAC AATAAAGACA ATGGTACTTG GACTCAGCTC
TGGTTGGTGT CAGATTATCA TGAGCATGGA TCCCTTTTTG ATTACTTAAA CAGATACACA
GTTACTGTGG AAGGAATGAT AAAACTTGCT CTGTCCACGG CGAGCGGTCT TGCCCATCTT
CACATGGAGA TTGTTGGTAC CCAAGGAAAG CCAGCCATTG CTCATAGAGA TTTGAAATCA
AAGAATATCT TGGTAAAGAA GAATGGAACT TGCTGTATTG CAGACTTAGG ACTGGCAGTA
AGACATGATT CAGCCACAGA TACCATTGAT ATTGCTCCAA ACCACAGAGT GGGAACAAAA
AGGTACATGG CCCCTGAAGT TCTCGATGAT TCCATAAATA TGAAACATTT TGAATCCTTC
AAACGTGCTG ACATCTATGC AATGGGCTTA GTATTCTGGG AAATTGCTCG ACGATGTTCC
ATTGGTGGAA TTCATGAAGA TTACCAACTG CCTTATTATG ATCTTGTACC TTCTGACCCA
TCAGTTGAAG AAATGAGAAA AGTTGTTTGT GAACAGAAGT TAAGGCCAAA TATCCCAAAC
AGATGGCAGA GCTGTGAAGC CTTGAGAGTA ATGGCTAAAA TTATGAGAGA ATGTTGGTAT
GCCAATGGAG CAGCTAGGCT TACAGCATTG CGGATTAAGA AAACATTATC GCAACTCAGT
CAACAGGAAG GCATCAAAAT GTAA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_001293139.1
CDS118..1641
Misc Feature(1)64..66(+)
Misc Feature(2)220..459(+)
Misc Feature(3)652..738(+)
Misc Feature(4)742..1599(+)
Misc Feature(5)754..1617(+)
Misc Feature(6)760..1260(+)
Misc Feature(7)760..1182(+)
Misc Feature(8)772..1260(+)
Misc Feature(9)853..930(+)
Misc Feature(10)1177..1260(+)
Exon (1)1..214
Gene:TGFBR1
Gene Synonym:
Exon (2)215..460
Gene:TGFBR1
Gene Synonym:
Exon (3)461..703
Gene:TGFBR1
Gene Synonym:
Exon (4)704..934
Gene:TGFBR1
Gene Synonym:
Exon (5)935..1102
Gene:TGFBR1
Gene Synonym:
Exon (6)1103..1259
Gene:TGFBR1
Gene Synonym:
Exon (7)1260..1384
Gene:TGFBR1
Gene Synonym:
Exon (8)1385..1515
Gene:TGFBR1
Gene Synonym:
Exon (9)1516..6528
Gene:TGFBR1
Gene Synonym:
Translation
Position Chain Variation Link

Target ORF information:

RefSeq Version NM_001306210
Organism Homo sapiens (human)
Definition Homo sapiens transforming growth factor, beta receptor 1 (TGFBR1), transcript variant 3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001306210

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
ATGGAGGCGG CGGTCGCTGC TCCGCGTCCC CGGCTGCTCC TCCTCGTGCT GGCGGCGGCG 
GCGGCGGCGG CGGCGGCGCT GCTCCCGGGG GCGACGGCGT TACAGTGTTT CTGCCACCTC
TGTACAAAAG ACAATTTTAC TTGTGTGACA GATGGGCTCT GCTTTGTCTC TGTCACAGAG
ACCACAGACA AAGTTATACA CAACAGCATG TGTATAGCTG AAATTGACTT AATTCCTCGA
GATAGGCCGT TTGTATGTGC ACCCTCTTCA AAAACTGGGT CTGTGACTAC AACATATTGC
TGCAATCAGG ACCATTGCAA TAAAATAGAA CTTCCAACTA CTGGCCCTTT TTCAGTAAAG
TCATCACCTG GCCTTGGTCC TGTGGAACTG GCAGCTGTCA TTGCTGGACC AGTGTGCTTC
GTCTGCATCT CACTCATGTT GATGGTCTAT ATCTGCCACA ACCGCACTGT CATTCACCAT
CGAGTGCCAA ATGAAGAGGA CCCTTCATTA GATCGCCCTT TTATTTCAGA GGGTACTACG
TTGAAAGACT TAATTTATGA TATGACAACG TCAGGTTCTG GCTCAGGTTT ACCATTGCTT
GTTCAGAGAA CAATTGCGAG AACTATTGTG TTACAAGAAA GCATTGGCAA AGGTCGATTT
GGAGAAGTTT GGAGAGGAAA GTGGCGGGGA GAAGAAGTTG CTGTTAAGAT ATTCTCCTCT
AGAGAAGAAC GTTCGTGGTT CCGTGAGGCA GAGATTTATC AAACTGTAAT GTTACGTCAT
GAAAACATCC TGGGATTTAT AGCAGCAGAC AATAAAGACA ATGGTACTTG GACTCAGCTC
TGGTTGGTGT CAGATTATCA TGAGCATGGA TCCCTTTTTG ATTACTTAAA CAGATACACA
GTTACTGTGG AAGGAATGAT AAAACTTGCT CTGTCCACGG CGAGCGGTCT TGCCCATCTT
CACATGGAGA TTGTTGGTAC CCAAGGAAAG CCAGCCATTG CTCATAGAGA TTTGAAATCA
AAGAATATCT TGGTAAAGAA GAATGGAACT TGCTGTATTG CAGACTTAGG ACTGGCAGTA
AGACATGATT CAGCCACAGA TACCATTGAT ATTGCTCCAA ACCACAGAGT GGGAACAAAA
AGGTACATGG CCCCTGAAGT TCTCGATGAT TCCATAAATA TGAAACATTT TGAATCCTTC
AAACGTGCTG ACATCTATGC AATGGGCTTA GTATTCTGGG AAATTGCTCG ACGATGTTCC
ATTGGTGGAA TTCATGAAGA TTACCAACTG CCTTATTATG ATCTTGTACC TTCTGACCCA
TCAGTTGAAG AAATGAGAAA AGTTGTTTGT GAACAGAAGT TAAGGCCAAA TATCCCAAAC
AGATGGCAGA GCTGTGAAGC CTTGAGAGTA ATGGCTAAAA TTATGAGAGA ATGTTGGTAT
GCCAATGGAG CAGCTAGGCT TACAGCATTG CGGATTAAGA AAACATTATC GCAACTCAGT
CAACAGGAAG GCATCAAAAT GTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.