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TGFBR1 cDNA ORF clone, Homo sapiens (human)

Gene Symbol TGFBR1
Entrez Gene ID 7046
Full Name transforming growth factor, beta receptor 1
Synonyms AAT5, ACVRLK4, ALK-5, ALK5, ESS1, LDS1, LDS1A, LDS2A, MSSE, SKR4, TGFR-1, tbetaR-I
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

9

9q22

Summary The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]. lac of sum
Disorder MIM:

190181

Disorder Html: Loeys-Dietz syndrome, type 1A, 609192 (3); Loeys-Dietz syndrome,

mRNA and Protein(s)

mRNA Protein Name
XM_011518948 XP_011517250 TGF-beta receptor type-1 isoform X2
XM_011518949 XP_011517251 TGF-beta receptor type-1 isoform X3
XM_011518950 XP_011517252 TGF-beta receptor type-1 isoform X4
NM_001130916 NP_001124388 TGF-beta receptor type-1 isoform 2 precursor
NM_004612 NP_004603 TGF-beta receptor type-1 isoform 1 precursor
NM_001306210 NP_001293139 TGF-beta receptor type-1 isoform 3 precursor



Homo sapiens (human) TGFBR1 NP_004603.1
Pan troglodytes (chimpanzee) TGFBR1 XP_001159299.1
Macaca mulatta (Rhesus monkey) TGFBR1 XP_001112621.1
Canis lupus familiaris (dog) TGFBR1 XP_538750.4
Bos taurus (cattle) TGFBR1 NP_777046.1
Mus musculus (house mouse) Tgfbr1 NP_033396.1
Rattus norvegicus (Norway rat) Tgfbr1 XP_006238215.1
Gallus gallus (chicken) TGFBR1 NP_989577.1
Danio rerio (zebrafish) tgfbr1a NP_001032772.2
Danio rerio (zebrafish) tgfbr1b NP_001108531.1
Drosophila melanogaster (fruit fly) babo NP_476999.1
Xenopus (Silurana) tropicalis (western clawed frog) tgfbr1 NP_001015961.1


GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following TGFBR1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TGFBR1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu60974 XM_011518948 PREDICTED: Homo sapiens transforming growth factor, beta receptor 1 (TGFBR1), transcript variant X2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $223.30
$319.00
OHu60975 XM_011518949 PREDICTED: Homo sapiens transforming growth factor, beta receptor 1 (TGFBR1), transcript variant X3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $223.30
$319.00
OHu60976 XM_011518950 PREDICTED: Homo sapiens transforming growth factor, beta receptor 1 (TGFBR1), transcript variant X4, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 5-7 $223.30
$319.00
OHu16616 NM_001130916 Homo sapiens transforming growth factor, beta receptor 1 (TGFBR1), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector TBD $265.30
$379.00
OHu17991 NM_004612 Homo sapiens transforming growth factor, beta receptor 1 (TGFBR1), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector TBD $300.30
$429.00
OHu43465 NM_001306210 Homo sapiens transforming growth factor, beta receptor 1 (TGFBR1), transcript variant 3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector TBD $307.30
$439.00
Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone 30% OFF
2-4 Clone 40% OFF
5 or more Clone 50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu60974
Clone ID Related Accession (Same CDS sequence) XM_011518948
Accession Version XM_011518948.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1317bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product TGF-beta receptor type-1 isoform X2
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_008470.20) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
ATGTGTATAG CTGAAATTGA CTTAATTCCT CGAGATAGGC CGTTTGTATG TGCACCCTCT 
TCAAAAACTG GGTCTGTGAC TACAACATAT TGCTGCAATC AGGACCATTG CAATAAAATA
GAACTTCCAA CTACTGGCCC TTTTTCAGTA AAGTCATCAC CTGGCCTTGG TCCTGTGGAA
CTGGCAGCTG TCATTGCTGG ACCAGTGTGC TTCGTCTGCA TCTCACTCAT GTTGATGGTC
TATATCTGCC ACAACCGCAC TGTCATTCAC CATCGAGTGC CAAATGAAGA GGACCCTTCA
TTAGATCGCC CTTTTATTTC AGAGGGTACT ACGTTGAAAG ACTTAATTTA TGATATGACA
ACGTCAGGTT CTGGCTCAGG TTTACCATTG CTTGTTCAGA GAACAATTGC GAGAACTATT
GTGTTACAAG AAAGCATTGG CAAAGGTCGA TTTGGAGAAG TTTGGAGAGG AAAGTGGCGG
GGAGAAGAAG TTGCTGTTAA GATATTCTCC TCTAGAGAAG AACGTTCGTG GTTCCGTGAG
GCAGAGATTT ATCAAACTGT AATGTTACGT CATGAAAACA TCCTGGGATT TATAGCAGCA
GACAATAAAG ACAATGGTAC TTGGACTCAG CTCTGGTTGG TGTCAGATTA TCATGAGCAT
GGATCCCTTT TTGATTACTT AAACAGATAC ACAGTTACTG TGGAAGGAAT GATAAAACTT
GCTCTGTCCA CGGCGAGCGG TCTTGCCCAT CTTCACATGG AGATTGTTGG TACCCAAGGA
AAGCCAGCCA TTGCTCATAG AGATTTGAAA TCAAAGAATA TCTTGGTAAA GAAGAATGGA
ACTTGCTGTA TTGCAGACTT AGGACTGGCA GTAAGACATG ATTCAGCCAC AGATACCATT
GATATTGCTC CAAACCACAG AGTGGGAACA AAAAGGTACA TGGCCCCTGA AGTTCTCGAT
GATTCCATAA ATATGAAACA TTTTGAATCC TTCAAACGTG CTGACATCTA TGCAATGGGC
TTAGTATTCT GGGAAATTGC TCGACGATGT TCCATTGGTG GAATTCATGA AGATTACCAA
CTGCCTTATT ATGATCTTGT ACCTTCTGAC CCATCAGTTG AAGAAATGAG AAAAGTTGTT
TGTGAACAGA AGTTAAGGCC AAATATCCCA AACAGATGGC AGAGCTGTGA AGCCTTGAGA
GTAATGGCTA AAATTATGAG AGAATGTTGG TATGCCAATG GAGCAGCTAG GCTTACAGCA
TTGCGGATTA AGAAAACATT ATCGCAACTC AGTCAACAGG AAGGCATCAA AATGTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011517250.1
CDS240..1556
Misc Feature(1)240..374(+)
Misc Feature(2)567..653(+)
Misc Feature(3)657..1514(+)
Misc Feature(4)669..1532(+)
Misc Feature(5)675..1175(+)
Misc Feature(6)675..1097(+)
Misc Feature(7)687..1175(+)
Misc Feature(8)768..845(+)
Misc Feature(9)1092..1175(+)
Translation

Target ORF information:

RefSeq Version XM_011518948
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens transforming growth factor, beta receptor 1 (TGFBR1), transcript variant X2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011518948

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
ATGTGTATAG CTGAAATTGA CTTAATTCCT CGAGATAGGC CGTTTGTATG TGCACCCTCT 
TCAAAAACTG GGTCTGTGAC TACAACATAT TGCTGCAATC AGGACCATTG CAATAAAATA
GAACTTCCAA CTACTGGCCC TTTTTCAGTA AAGTCATCAC CTGGCCTTGG TCCTGTGGAA
CTGGCAGCTG TCATTGCTGG ACCAGTGTGC TTCGTCTGCA TCTCACTCAT GTTGATGGTC
TATATCTGCC ACAACCGCAC TGTCATTCAC CATCGAGTGC CAAATGAAGA GGACCCTTCA
TTAGATCGCC CTTTTATTTC AGAGGGTACT ACGTTGAAAG ACTTAATTTA TGATATGACA
ACGTCAGGTT CTGGCTCAGG TTTACCATTG CTTGTTCAGA GAACAATTGC GAGAACTATT
GTGTTACAAG AAAGCATTGG CAAAGGTCGA TTTGGAGAAG TTTGGAGAGG AAAGTGGCGG
GGAGAAGAAG TTGCTGTTAA GATATTCTCC TCTAGAGAAG AACGTTCGTG GTTCCGTGAG
GCAGAGATTT ATCAAACTGT AATGTTACGT CATGAAAACA TCCTGGGATT TATAGCAGCA
GACAATAAAG ACAATGGTAC TTGGACTCAG CTCTGGTTGG TGTCAGATTA TCATGAGCAT
GGATCCCTTT TTGATTACTT AAACAGATAC ACAGTTACTG TGGAAGGAAT GATAAAACTT
GCTCTGTCCA CGGCGAGCGG TCTTGCCCAT CTTCACATGG AGATTGTTGG TACCCAAGGA
AAGCCAGCCA TTGCTCATAG AGATTTGAAA TCAAAGAATA TCTTGGTAAA GAAGAATGGA
ACTTGCTGTA TTGCAGACTT AGGACTGGCA GTAAGACATG ATTCAGCCAC AGATACCATT
GATATTGCTC CAAACCACAG AGTGGGAACA AAAAGGTACA TGGCCCCTGA AGTTCTCGAT
GATTCCATAA ATATGAAACA TTTTGAATCC TTCAAACGTG CTGACATCTA TGCAATGGGC
TTAGTATTCT GGGAAATTGC TCGACGATGT TCCATTGGTG GAATTCATGA AGATTACCAA
CTGCCTTATT ATGATCTTGT ACCTTCTGAC CCATCAGTTG AAGAAATGAG AAAAGTTGTT
TGTGAACAGA AGTTAAGGCC AAATATCCCA AACAGATGGC AGAGCTGTGA AGCCTTGAGA
GTAATGGCTA AAATTATGAG AGAATGTTGG TATGCCAATG GAGCAGCTAG GCTTACAGCA
TTGCGGATTA AGAAAACATT ATCGCAACTC AGTCAACAGG AAGGCATCAA AATGTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu60975
Clone ID Related Accession (Same CDS sequence) XM_011518949
Accession Version XM_011518949.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1305bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product TGF-beta receptor type-1 isoform X3
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_008470.20) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
ATGTGTATAG CTGAAATTGA CTTAATTCCT CGAGATAGGC CGTTTGTATG TGCACCCTCT 
TCAAAAACTG GGTCTGTGAC TACAACATAT TGCTGCAATC AGGACCATTG CAATAAAATA
GAACTTCCAA CTACTGTAAA GTCATCACCT GGCCTTGGTC CTGTGGAACT GGCAGCTGTC
ATTGCTGGAC CAGTGTGCTT CGTCTGCATC TCACTCATGT TGATGGTCTA TATCTGCCAC
AACCGCACTG TCATTCACCA TCGAGTGCCA AATGAAGAGG ACCCTTCATT AGATCGCCCT
TTTATTTCAG AGGGTACTAC GTTGAAAGAC TTAATTTATG ATATGACAAC GTCAGGTTCT
GGCTCAGGTT TACCATTGCT TGTTCAGAGA ACAATTGCGA GAACTATTGT GTTACAAGAA
AGCATTGGCA AAGGTCGATT TGGAGAAGTT TGGAGAGGAA AGTGGCGGGG AGAAGAAGTT
GCTGTTAAGA TATTCTCCTC TAGAGAAGAA CGTTCGTGGT TCCGTGAGGC AGAGATTTAT
CAAACTGTAA TGTTACGTCA TGAAAACATC CTGGGATTTA TAGCAGCAGA CAATAAAGAC
AATGGTACTT GGACTCAGCT CTGGTTGGTG TCAGATTATC ATGAGCATGG ATCCCTTTTT
GATTACTTAA ACAGATACAC AGTTACTGTG GAAGGAATGA TAAAACTTGC TCTGTCCACG
GCGAGCGGTC TTGCCCATCT TCACATGGAG ATTGTTGGTA CCCAAGGAAA GCCAGCCATT
GCTCATAGAG ATTTGAAATC AAAGAATATC TTGGTAAAGA AGAATGGAAC TTGCTGTATT
GCAGACTTAG GACTGGCAGT AAGACATGAT TCAGCCACAG ATACCATTGA TATTGCTCCA
AACCACAGAG TGGGAACAAA AAGGTACATG GCCCCTGAAG TTCTCGATGA TTCCATAAAT
ATGAAACATT TTGAATCCTT CAAACGTGCT GACATCTATG CAATGGGCTT AGTATTCTGG
GAAATTGCTC GACGATGTTC CATTGGTGGA ATTCATGAAG ATTACCAACT GCCTTATTAT
GATCTTGTAC CTTCTGACCC ATCAGTTGAA GAAATGAGAA AAGTTGTTTG TGAACAGAAG
TTAAGGCCAA ATATCCCAAA CAGATGGCAG AGCTGTGAAG CCTTGAGAGT AATGGCTAAA
ATTATGAGAG AATGTTGGTA TGCCAATGGA GCAGCTAGGC TTACAGCATT GCGGATTAAG
AAAACATTAT CGCAACTCAG TCAACAGGAA GGCATCAAAA TGTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011517251.1
CDS180..1484
Misc Feature(1)180..314(+)
Misc Feature(2)495..581(+)
Misc Feature(3)585..1442(+)
Misc Feature(4)597..1460(+)
Misc Feature(5)603..1103(+)
Misc Feature(6)603..1025(+)
Misc Feature(7)615..1103(+)
Misc Feature(8)696..773(+)
Misc Feature(9)1020..1103(+)
Translation

Target ORF information:

RefSeq Version XM_011518949
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens transforming growth factor, beta receptor 1 (TGFBR1), transcript variant X3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011518949

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
ATGTGTATAG CTGAAATTGA CTTAATTCCT CGAGATAGGC CGTTTGTATG TGCACCCTCT 
TCAAAAACTG GGTCTGTGAC TACAACATAT TGCTGCAATC AGGACCATTG CAATAAAATA
GAACTTCCAA CTACTGTAAA GTCATCACCT GGCCTTGGTC CTGTGGAACT GGCAGCTGTC
ATTGCTGGAC CAGTGTGCTT CGTCTGCATC TCACTCATGT TGATGGTCTA TATCTGCCAC
AACCGCACTG TCATTCACCA TCGAGTGCCA AATGAAGAGG ACCCTTCATT AGATCGCCCT
TTTATTTCAG AGGGTACTAC GTTGAAAGAC TTAATTTATG ATATGACAAC GTCAGGTTCT
GGCTCAGGTT TACCATTGCT TGTTCAGAGA ACAATTGCGA GAACTATTGT GTTACAAGAA
AGCATTGGCA AAGGTCGATT TGGAGAAGTT TGGAGAGGAA AGTGGCGGGG AGAAGAAGTT
GCTGTTAAGA TATTCTCCTC TAGAGAAGAA CGTTCGTGGT TCCGTGAGGC AGAGATTTAT
CAAACTGTAA TGTTACGTCA TGAAAACATC CTGGGATTTA TAGCAGCAGA CAATAAAGAC
AATGGTACTT GGACTCAGCT CTGGTTGGTG TCAGATTATC ATGAGCATGG ATCCCTTTTT
GATTACTTAA ACAGATACAC AGTTACTGTG GAAGGAATGA TAAAACTTGC TCTGTCCACG
GCGAGCGGTC TTGCCCATCT TCACATGGAG ATTGTTGGTA CCCAAGGAAA GCCAGCCATT
GCTCATAGAG ATTTGAAATC AAAGAATATC TTGGTAAAGA AGAATGGAAC TTGCTGTATT
GCAGACTTAG GACTGGCAGT AAGACATGAT TCAGCCACAG ATACCATTGA TATTGCTCCA
AACCACAGAG TGGGAACAAA AAGGTACATG GCCCCTGAAG TTCTCGATGA TTCCATAAAT
ATGAAACATT TTGAATCCTT CAAACGTGCT GACATCTATG CAATGGGCTT AGTATTCTGG
GAAATTGCTC GACGATGTTC CATTGGTGGA ATTCATGAAG ATTACCAACT GCCTTATTAT
GATCTTGTAC CTTCTGACCC ATCAGTTGAA GAAATGAGAA AAGTTGTTTG TGAACAGAAG
TTAAGGCCAA ATATCCCAAA CAGATGGCAG AGCTGTGAAG CCTTGAGAGT AATGGCTAAA
ATTATGAGAG AATGTTGGTA TGCCAATGGA GCAGCTAGGC TTACAGCATT GCGGATTAAG
AAAACATTAT CGCAACTCAG TCAACAGGAA GGCATCAAAA TGTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu60976
Clone ID Related Accession (Same CDS sequence) XM_011518950
Accession Version XM_011518950.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1074bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product TGF-beta receptor type-1 isoform X4
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_008470.20) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
ATGTGTATAG CTGAAATTGA CTTAATTCCT CGAGATAGGC CGTTTGTATG TGCACCCTCT 
TCAAAAACTG GGTCTGTGAC TACAACATAT TGCTGCAATC AGGACCATTG CAATAAAATA
GAACTTCCAA CTACTGGTTT ACCATTGCTT GTTCAGAGAA CAATTGCGAG AACTATTGTG
TTACAAGAAA GCATTGGCAA AGGTCGATTT GGAGAAGTTT GGAGAGGAAA GTGGCGGGGA
GAAGAAGTTG CTGTTAAGAT ATTCTCCTCT AGAGAAGAAC GTTCGTGGTT CCGTGAGGCA
GAGATTTATC AAACTGTAAT GTTACGTCAT GAAAACATCC TGGGATTTAT AGCAGCAGAC
AATAAAGACA ATGGTACTTG GACTCAGCTC TGGTTGGTGT CAGATTATCA TGAGCATGGA
TCCCTTTTTG ATTACTTAAA CAGATACACA GTTACTGTGG AAGGAATGAT AAAACTTGCT
CTGTCCACGG CGAGCGGTCT TGCCCATCTT CACATGGAGA TTGTTGGTAC CCAAGGAAAG
CCAGCCATTG CTCATAGAGA TTTGAAATCA AAGAATATCT TGGTAAAGAA GAATGGAACT
TGCTGTATTG CAGACTTAGG ACTGGCAGTA AGACATGATT CAGCCACAGA TACCATTGAT
ATTGCTCCAA ACCACAGAGT GGGAACAAAA AGGTACATGG CCCCTGAAGT TCTCGATGAT
TCCATAAATA TGAAACATTT TGAATCCTTC AAACGTGCTG ACATCTATGC AATGGGCTTA
GTATTCTGGG AAATTGCTCG ACGATGTTCC ATTGGTGGAA TTCATGAAGA TTACCAACTG
CCTTATTATG ATCTTGTACC TTCTGACCCA TCAGTTGAAG AAATGAGAAA AGTTGTTTGT
GAACAGAAGT TAAGGCCAAA TATCCCAAAC AGATGGCAGA GCTGTGAAGC CTTGAGAGTA
ATGGCTAAAA TTATGAGAGA ATGTTGGTAT GCCAATGGAG CAGCTAGGCT TACAGCATTG
CGGATTAAGA AAACATTATC GCAACTCAGT CAACAGGAAG GCATCAAAAT GTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011517252.1
CDS334..1407
Misc Feature(1)334..468(+)
Misc Feature(2)466..504(+)
Misc Feature(3)508..1365(+)
Misc Feature(4)520..1383(+)
Misc Feature(5)526..1026(+)
Misc Feature(6)526..948(+)
Misc Feature(7)538..1026(+)
Misc Feature(8)619..696(+)
Misc Feature(9)943..1026(+)
Translation

Target ORF information:

RefSeq Version XM_011518950
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens transforming growth factor, beta receptor 1 (TGFBR1), transcript variant X4, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011518950

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
ATGTGTATAG CTGAAATTGA CTTAATTCCT CGAGATAGGC CGTTTGTATG TGCACCCTCT 
TCAAAAACTG GGTCTGTGAC TACAACATAT TGCTGCAATC AGGACCATTG CAATAAAATA
GAACTTCCAA CTACTGGTTT ACCATTGCTT GTTCAGAGAA CAATTGCGAG AACTATTGTG
TTACAAGAAA GCATTGGCAA AGGTCGATTT GGAGAAGTTT GGAGAGGAAA GTGGCGGGGA
GAAGAAGTTG CTGTTAAGAT ATTCTCCTCT AGAGAAGAAC GTTCGTGGTT CCGTGAGGCA
GAGATTTATC AAACTGTAAT GTTACGTCAT GAAAACATCC TGGGATTTAT AGCAGCAGAC
AATAAAGACA ATGGTACTTG GACTCAGCTC TGGTTGGTGT CAGATTATCA TGAGCATGGA
TCCCTTTTTG ATTACTTAAA CAGATACACA GTTACTGTGG AAGGAATGAT AAAACTTGCT
CTGTCCACGG CGAGCGGTCT TGCCCATCTT CACATGGAGA TTGTTGGTAC CCAAGGAAAG
CCAGCCATTG CTCATAGAGA TTTGAAATCA AAGAATATCT TGGTAAAGAA GAATGGAACT
TGCTGTATTG CAGACTTAGG ACTGGCAGTA AGACATGATT CAGCCACAGA TACCATTGAT
ATTGCTCCAA ACCACAGAGT GGGAACAAAA AGGTACATGG CCCCTGAAGT TCTCGATGAT
TCCATAAATA TGAAACATTT TGAATCCTTC AAACGTGCTG ACATCTATGC AATGGGCTTA
GTATTCTGGG AAATTGCTCG ACGATGTTCC ATTGGTGGAA TTCATGAAGA TTACCAACTG
CCTTATTATG ATCTTGTACC TTCTGACCCA TCAGTTGAAG AAATGAGAAA AGTTGTTTGT
GAACAGAAGT TAAGGCCAAA TATCCCAAAC AGATGGCAGA GCTGTGAAGC CTTGAGAGTA
ATGGCTAAAA TTATGAGAGA ATGTTGGTAT GCCAATGGAG CAGCTAGGCT TACAGCATTG
CGGATTAAGA AAACATTATC GCAACTCAGT CAACAGGAAG GCATCAAAAT GTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu16616
Clone ID Related Accession (Same CDS sequence) NM_001130916
Accession Version NM_001130916.2 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1281bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 21-MAY-2015
Organism Homo sapiens (human)
Product TGF-beta receptor type-1 isoform 2 precursor
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK302059.1, BC071181.1 and AJ619019.2. On May 4, 2015 this sequence version replaced gi:195963411. Transcript Variant: This variant (2) lacks an in-frame exon in the 5' coding region, compared to variant 3. The encoded isoform (2) is shorter than isoform 3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC071181.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
ATGGAGGCGG CGGTCGCTGC TCCGCGTCCC CGGCTGCTCC TCCTCGTGCT GGCGGCGGCG 
GCGGCGGCGG CGGCGGCGCT GCTCCCGGGG GCGACGGCGT TACAGTGTTT CTGCCACCTC
TGTACAAAAG ACAATTTTAC TTGTGTGACA GATGGGCTCT GCTTTGTCTC TGTCACAGAG
ACCACAGACA AAGTTATACA CAACAGCATG TGTATAGCTG AAATTGACTT AATTCCTCGA
GATAGGCCGT TTGTATGTGC ACCCTCTTCA AAAACTGGGT CTGTGACTAC AACATATTGC
TGCAATCAGG ACCATTGCAA TAAAATAGAA CTTCCAACTA CTGGTTTACC ATTGCTTGTT
CAGAGAACAA TTGCGAGAAC TATTGTGTTA CAAGAAAGCA TTGGCAAAGG TCGATTTGGA
GAAGTTTGGA GAGGAAAGTG GCGGGGAGAA GAAGTTGCTG TTAAGATATT CTCCTCTAGA
GAAGAACGTT CGTGGTTCCG TGAGGCAGAG ATTTATCAAA CTGTAATGTT ACGTCATGAA
AACATCCTGG GATTTATAGC AGCAGACAAT AAAGACAATG GTACTTGGAC TCAGCTCTGG
TTGGTGTCAG ATTATCATGA GCATGGATCC CTTTTTGATT ACTTAAACAG ATACACAGTT
ACTGTGGAAG GAATGATAAA ACTTGCTCTG TCCACGGCGA GCGGTCTTGC CCATCTTCAC
ATGGAGATTG TTGGTACCCA AGGAAAGCCA GCCATTGCTC ATAGAGATTT GAAATCAAAG
AATATCTTGG TAAAGAAGAA TGGAACTTGC TGTATTGCAG ACTTAGGACT GGCAGTAAGA
CATGATTCAG CCACAGATAC CATTGATATT GCTCCAAACC ACAGAGTGGG AACAAAAAGG
TACATGGCCC CTGAAGTTCT CGATGATTCC ATAAATATGA AACATTTTGA ATCCTTCAAA
CGTGCTGACA TCTATGCAAT GGGCTTAGTA TTCTGGGAAA TTGCTCGACG ATGTTCCATT
GGTGGAATTC ATGAAGATTA CCAACTGCCT TATTATGATC TTGTACCTTC TGACCCATCA
GTTGAAGAAA TGAGAAAAGT TGTTTGTGAA CAGAAGTTAA GGCCAAATAT CCCAAACAGA
TGGCAGAGCT GTGAAGCCTT GAGAGTAATG GCTAAAATTA TGAGAGAATG TTGGTATGCC
AATGGAGCAG CTAGGCTTAC AGCATTGCGG ATTAAGAAAA CATTATCGCA ACTCAGTCAA
CAGGAAGGCA TCAAAATGTA A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001124388.1
CDS118..1398
Misc Feature(1)64..66(+)
Misc Feature(2)220..459(+)
Misc Feature(3)457..495(+)
Misc Feature(4)499..1356(+)
Misc Feature(5)511..1374(+)
Misc Feature(6)517..1017(+)
Misc Feature(7)517..939(+)
Misc Feature(8)529..1017(+)
Misc Feature(9)610..687(+)
Misc Feature(10)934..1017(+)
Exon (1)1..214
Gene:TGFBR1
Gene Synonym:
Exon (2)215..460
Gene:TGFBR1
Gene Synonym:
Exon (3)461..691
Gene:TGFBR1
Gene Synonym:
Exon (4)692..859
Gene:TGFBR1
Gene Synonym:
Exon (5)860..1016
Gene:TGFBR1
Gene Synonym:
Exon (6)1017..1141
Gene:TGFBR1
Gene Synonym:
Exon (7)1142..1272
Gene:TGFBR1
Gene Synonym:
Exon (8)1273..6285
Gene:TGFBR1
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_001130916
Organism Homo sapiens (human)
Definition Homo sapiens transforming growth factor, beta receptor 1 (TGFBR1), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001130916

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
ATGGAGGCGG CGGTCGCTGC TCCGCGTCCC CGGCTGCTCC TCCTCGTGCT GGCGGCGGCG 
GCGGCGGCGG CGGCGGCGCT GCTCCCGGGG GCGACGGCGT TACAGTGTTT CTGCCACCTC
TGTACAAAAG ACAATTTTAC TTGTGTGACA GATGGGCTCT GCTTTGTCTC TGTCACAGAG
ACCACAGACA AAGTTATACA CAACAGCATG TGTATAGCTG AAATTGACTT AATTCCTCGA
GATAGGCCGT TTGTATGTGC ACCCTCTTCA AAAACTGGGT CTGTGACTAC AACATATTGC
TGCAATCAGG ACCATTGCAA TAAAATAGAA CTTCCAACTA CTGGTTTACC ATTGCTTGTT
CAGAGAACAA TTGCGAGAAC TATTGTGTTA CAAGAAAGCA TTGGCAAAGG TCGATTTGGA
GAAGTTTGGA GAGGAAAGTG GCGGGGAGAA GAAGTTGCTG TTAAGATATT CTCCTCTAGA
GAAGAACGTT CGTGGTTCCG TGAGGCAGAG ATTTATCAAA CTGTAATGTT ACGTCATGAA
AACATCCTGG GATTTATAGC AGCAGACAAT AAAGACAATG GTACTTGGAC TCAGCTCTGG
TTGGTGTCAG ATTATCATGA GCATGGATCC CTTTTTGATT ACTTAAACAG ATACACAGTT
ACTGTGGAAG GAATGATAAA ACTTGCTCTG TCCACGGCGA GCGGTCTTGC CCATCTTCAC
ATGGAGATTG TTGGTACCCA AGGAAAGCCA GCCATTGCTC ATAGAGATTT GAAATCAAAG
AATATCTTGG TAAAGAAGAA TGGAACTTGC TGTATTGCAG ACTTAGGACT GGCAGTAAGA
CATGATTCAG CCACAGATAC CATTGATATT GCTCCAAACC ACAGAGTGGG AACAAAAAGG
TACATGGCCC CTGAAGTTCT CGATGATTCC ATAAATATGA AACATTTTGA ATCCTTCAAA
CGTGCTGACA TCTATGCAAT GGGCTTAGTA TTCTGGGAAA TTGCTCGACG ATGTTCCATT
GGTGGAATTC ATGAAGATTA CCAACTGCCT TATTATGATC TTGTACCTTC TGACCCATCA
GTTGAAGAAA TGAGAAAAGT TGTTTGTGAA CAGAAGTTAA GGCCAAATAT CCCAAACAGA
TGGCAGAGCT GTGAAGCCTT GAGAGTAATG GCTAAAATTA TGAGAGAATG TTGGTATGCC
AATGGAGCAG CTAGGCTTAC AGCATTGCGG ATTAAGAAAA CATTATCGCA ACTCAGTCAA
CAGGAAGGCA TCAAAATGTA A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu17991
Clone ID Related Accession (Same CDS sequence) NM_004612
Accession Version NM_004612.3 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1512bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 21-MAY-2015
Organism Homo sapiens (human)
Product TGF-beta receptor type-1 isoform 1 precursor
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK302059.1, L11695.1 and AJ619019.2. This sequence is a reference standard in the RefSeqGene project. On May 4, 2015 this sequence version replaced gi:66346739. Transcript Variant: This variant (1) uses an alternate in-frame splice site in the 5' coding region, compared to variant 3. The encoded isoform (1) is shorter than isoform 3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: L11695.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
ATGGAGGCGG CGGTCGCTGC TCCGCGTCCC CGGCTGCTCC TCCTCGTGCT GGCGGCGGCG 
GCGGCGGCGG CGGCGGCGCT GCTCCCGGGG GCGACGGCGT TACAGTGTTT CTGCCACCTC
TGTACAAAAG ACAATTTTAC TTGTGTGACA GATGGGCTCT GCTTTGTCTC TGTCACAGAG
ACCACAGACA AAGTTATACA CAACAGCATG TGTATAGCTG AAATTGACTT AATTCCTCGA
GATAGGCCGT TTGTATGTGC ACCCTCTTCA AAAACTGGGT CTGTGACTAC AACATATTGC
TGCAATCAGG ACCATTGCAA TAAAATAGAA CTTCCAACTA CTGTAAAGTC ATCACCTGGC
CTTGGTCCTG TGGAACTGGC AGCTGTCATT GCTGGACCAG TGTGCTTCGT CTGCATCTCA
CTCATGTTGA TGGTCTATAT CTGCCACAAC CGCACTGTCA TTCACCATCG AGTGCCAAAT
GAAGAGGACC CTTCATTAGA TCGCCCTTTT ATTTCAGAGG GTACTACGTT GAAAGACTTA
ATTTATGATA TGACAACGTC AGGTTCTGGC TCAGGTTTAC CATTGCTTGT TCAGAGAACA
ATTGCGAGAA CTATTGTGTT ACAAGAAAGC ATTGGCAAAG GTCGATTTGG AGAAGTTTGG
AGAGGAAAGT GGCGGGGAGA AGAAGTTGCT GTTAAGATAT TCTCCTCTAG AGAAGAACGT
TCGTGGTTCC GTGAGGCAGA GATTTATCAA ACTGTAATGT TACGTCATGA AAACATCCTG
GGATTTATAG CAGCAGACAA TAAAGACAAT GGTACTTGGA CTCAGCTCTG GTTGGTGTCA
GATTATCATG AGCATGGATC CCTTTTTGAT TACTTAAACA GATACACAGT TACTGTGGAA
GGAATGATAA AACTTGCTCT GTCCACGGCG AGCGGTCTTG CCCATCTTCA CATGGAGATT
GTTGGTACCC AAGGAAAGCC AGCCATTGCT CATAGAGATT TGAAATCAAA GAATATCTTG
GTAAAGAAGA ATGGAACTTG CTGTATTGCA GACTTAGGAC TGGCAGTAAG ACATGATTCA
GCCACAGATA CCATTGATAT TGCTCCAAAC CACAGAGTGG GAACAAAAAG GTACATGGCC
CCTGAAGTTC TCGATGATTC CATAAATATG AAACATTTTG AATCCTTCAA ACGTGCTGAC
ATCTATGCAA TGGGCTTAGT ATTCTGGGAA ATTGCTCGAC GATGTTCCAT TGGTGGAATT
CATGAAGATT ACCAACTGCC TTATTATGAT CTTGTACCTT CTGACCCATC AGTTGAAGAA
ATGAGAAAAG TTGTTTGTGA ACAGAAGTTA AGGCCAAATA TCCCAAACAG ATGGCAGAGC
TGTGAAGCCT TGAGAGTAAT GGCTAAAATT ATGAGAGAAT GTTGGTATGC CAATGGAGCA
GCTAGGCTTA CAGCATTGCG GATTAAGAAA ACATTATCGC AACTCAGTCA ACAGGAAGGC
ATCAAAATGT AA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_004603.1
CDS118..1629
Misc Feature(1)64..66(+)
Misc Feature(2)220..459(+)
Misc Feature(3)631..633(+)
Misc Feature(4)640..726(+)
Misc Feature(5)643..645(+)
Misc Feature(6)730..1587(+)
Misc Feature(7)742..1605(+)
Misc Feature(8)748..1248(+)
Misc Feature(9)748..1170(+)
Misc Feature(10)760..1248(+)
Misc Feature(11)841..918(+)
Misc Feature(12)1165..1248(+)
Exon (1)1..214
Gene:TGFBR1
Gene Synonym:
Exon (2)215..460
Gene:TGFBR1
Gene Synonym:
Exon (3)461..691
Gene:TGFBR1
Gene Synonym:
Exon (4)692..922
Gene:TGFBR1
Gene Synonym:
Exon (5)923..1090
Gene:TGFBR1
Gene Synonym:
Exon (6)1091..1247
Gene:TGFBR1
Gene Synonym:
Exon (7)1248..1372
Gene:TGFBR1
Gene Synonym:
Exon (8)1373..1503
Gene:TGFBR1
Gene Synonym:
Exon (9)1504..6516
Gene:TGFBR1
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_004612
Organism Homo sapiens (human)
Definition Homo sapiens transforming growth factor, beta receptor 1 (TGFBR1), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_004612

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
ATGGAGGCGG CGGTCGCTGC TCCGCGTCCC CGGCTGCTCC TCCTCGTGCT GGCGGCGGCG 
GCGGCGGCGG CGGCGGCGCT GCTCCCGGGG GCGACGGCGT TACAGTGTTT CTGCCACCTC
TGTACAAAAG ACAATTTTAC TTGTGTGACA GATGGGCTCT GCTTTGTCTC TGTCACAGAG
ACCACAGACA AAGTTATACA CAACAGCATG TGTATAGCTG AAATTGACTT AATTCCTCGA
GATAGGCCGT TTGTATGTGC ACCCTCTTCA AAAACTGGGT CTGTGACTAC AACATATTGC
TGCAATCAGG ACCATTGCAA TAAAATAGAA CTTCCAACTA CTGTAAAGTC ATCACCTGGC
CTTGGTCCTG TGGAACTGGC AGCTGTCATT GCTGGACCAG TGTGCTTCGT CTGCATCTCA
CTCATGTTGA TGGTCTATAT CTGCCACAAC CGCACTGTCA TTCACCATCG AGTGCCAAAT
GAAGAGGACC CTTCATTAGA TCGCCCTTTT ATTTCAGAGG GTACTACGTT GAAAGACTTA
ATTTATGATA TGACAACGTC AGGTTCTGGC TCAGGTTTAC CATTGCTTGT TCAGAGAACA
ATTGCGAGAA CTATTGTGTT ACAAGAAAGC ATTGGCAAAG GTCGATTTGG AGAAGTTTGG
AGAGGAAAGT GGCGGGGAGA AGAAGTTGCT GTTAAGATAT TCTCCTCTAG AGAAGAACGT
TCGTGGTTCC GTGAGGCAGA GATTTATCAA ACTGTAATGT TACGTCATGA AAACATCCTG
GGATTTATAG CAGCAGACAA TAAAGACAAT GGTACTTGGA CTCAGCTCTG GTTGGTGTCA
GATTATCATG AGCATGGATC CCTTTTTGAT TACTTAAACA GATACACAGT TACTGTGGAA
GGAATGATAA AACTTGCTCT GTCCACGGCG AGCGGTCTTG CCCATCTTCA CATGGAGATT
GTTGGTACCC AAGGAAAGCC AGCCATTGCT CATAGAGATT TGAAATCAAA GAATATCTTG
GTAAAGAAGA ATGGAACTTG CTGTATTGCA GACTTAGGAC TGGCAGTAAG ACATGATTCA
GCCACAGATA CCATTGATAT TGCTCCAAAC CACAGAGTGG GAACAAAAAG GTACATGGCC
CCTGAAGTTC TCGATGATTC CATAAATATG AAACATTTTG AATCCTTCAA ACGTGCTGAC
ATCTATGCAA TGGGCTTAGT ATTCTGGGAA ATTGCTCGAC GATGTTCCAT TGGTGGAATT
CATGAAGATT ACCAACTGCC TTATTATGAT CTTGTACCTT CTGACCCATC AGTTGAAGAA
ATGAGAAAAG TTGTTTGTGA ACAGAAGTTA AGGCCAAATA TCCCAAACAG ATGGCAGAGC
TGTGAAGCCT TGAGAGTAAT GGCTAAAATT ATGAGAGAAT GTTGGTATGC CAATGGAGCA
GCTAGGCTTA CAGCATTGCG GATTAAGAAA ACATTATCGC AACTCAGTCA ACAGGAAGGC
ATCAAAATGT AA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu43465
Clone ID Related Accession (Same CDS sequence) NM_001306210
Accession Version NM_001306210.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1524bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 21-MAY-2015
Organism Homo sapiens (human)
Product TGF-beta receptor type-1 isoform 3 precursor
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK302059.1 and AJ619019.2. On May 4, 2015 this sequence version replaced gi:530391448. Transcript Variant: This variant (3) represents the longest transcript and encodes the longest isoform (3). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AJ619019.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
ATGGAGGCGG CGGTCGCTGC TCCGCGTCCC CGGCTGCTCC TCCTCGTGCT GGCGGCGGCG 
GCGGCGGCGG CGGCGGCGCT GCTCCCGGGG GCGACGGCGT TACAGTGTTT CTGCCACCTC
TGTACAAAAG ACAATTTTAC TTGTGTGACA GATGGGCTCT GCTTTGTCTC TGTCACAGAG
ACCACAGACA AAGTTATACA CAACAGCATG TGTATAGCTG AAATTGACTT AATTCCTCGA
GATAGGCCGT TTGTATGTGC ACCCTCTTCA AAAACTGGGT CTGTGACTAC AACATATTGC
TGCAATCAGG ACCATTGCAA TAAAATAGAA CTTCCAACTA CTGGCCCTTT TTCAGTAAAG
TCATCACCTG GCCTTGGTCC TGTGGAACTG GCAGCTGTCA TTGCTGGACC AGTGTGCTTC
GTCTGCATCT CACTCATGTT GATGGTCTAT ATCTGCCACA ACCGCACTGT CATTCACCAT
CGAGTGCCAA ATGAAGAGGA CCCTTCATTA GATCGCCCTT TTATTTCAGA GGGTACTACG
TTGAAAGACT TAATTTATGA TATGACAACG TCAGGTTCTG GCTCAGGTTT ACCATTGCTT
GTTCAGAGAA CAATTGCGAG AACTATTGTG TTACAAGAAA GCATTGGCAA AGGTCGATTT
GGAGAAGTTT GGAGAGGAAA GTGGCGGGGA GAAGAAGTTG CTGTTAAGAT ATTCTCCTCT
AGAGAAGAAC GTTCGTGGTT CCGTGAGGCA GAGATTTATC AAACTGTAAT GTTACGTCAT
GAAAACATCC TGGGATTTAT AGCAGCAGAC AATAAAGACA ATGGTACTTG GACTCAGCTC
TGGTTGGTGT CAGATTATCA TGAGCATGGA TCCCTTTTTG ATTACTTAAA CAGATACACA
GTTACTGTGG AAGGAATGAT AAAACTTGCT CTGTCCACGG CGAGCGGTCT TGCCCATCTT
CACATGGAGA TTGTTGGTAC CCAAGGAAAG CCAGCCATTG CTCATAGAGA TTTGAAATCA
AAGAATATCT TGGTAAAGAA GAATGGAACT TGCTGTATTG CAGACTTAGG ACTGGCAGTA
AGACATGATT CAGCCACAGA TACCATTGAT ATTGCTCCAA ACCACAGAGT GGGAACAAAA
AGGTACATGG CCCCTGAAGT TCTCGATGAT TCCATAAATA TGAAACATTT TGAATCCTTC
AAACGTGCTG ACATCTATGC AATGGGCTTA GTATTCTGGG AAATTGCTCG ACGATGTTCC
ATTGGTGGAA TTCATGAAGA TTACCAACTG CCTTATTATG ATCTTGTACC TTCTGACCCA
TCAGTTGAAG AAATGAGAAA AGTTGTTTGT GAACAGAAGT TAAGGCCAAA TATCCCAAAC
AGATGGCAGA GCTGTGAAGC CTTGAGAGTA ATGGCTAAAA TTATGAGAGA ATGTTGGTAT
GCCAATGGAG CAGCTAGGCT TACAGCATTG CGGATTAAGA AAACATTATC GCAACTCAGT
CAACAGGAAG GCATCAAAAT GTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001293139.1
CDS118..1641
Misc Feature(1)64..66(+)
Misc Feature(2)220..459(+)
Misc Feature(3)652..738(+)
Misc Feature(4)742..1599(+)
Misc Feature(5)754..1617(+)
Misc Feature(6)760..1260(+)
Misc Feature(7)760..1182(+)
Misc Feature(8)772..1260(+)
Misc Feature(9)853..930(+)
Misc Feature(10)1177..1260(+)
Exon (1)1..214
Gene:TGFBR1
Gene Synonym:
Exon (2)215..460
Gene:TGFBR1
Gene Synonym:
Exon (3)461..703
Gene:TGFBR1
Gene Synonym:
Exon (4)704..934
Gene:TGFBR1
Gene Synonym:
Exon (5)935..1102
Gene:TGFBR1
Gene Synonym:
Exon (6)1103..1259
Gene:TGFBR1
Gene Synonym:
Exon (7)1260..1384
Gene:TGFBR1
Gene Synonym:
Exon (8)1385..1515
Gene:TGFBR1
Gene Synonym:
Exon (9)1516..6528
Gene:TGFBR1
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_001306210
Organism Homo sapiens (human)
Definition Homo sapiens transforming growth factor, beta receptor 1 (TGFBR1), transcript variant 3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001306210

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
ATGGAGGCGG CGGTCGCTGC TCCGCGTCCC CGGCTGCTCC TCCTCGTGCT GGCGGCGGCG 
GCGGCGGCGG CGGCGGCGCT GCTCCCGGGG GCGACGGCGT TACAGTGTTT CTGCCACCTC
TGTACAAAAG ACAATTTTAC TTGTGTGACA GATGGGCTCT GCTTTGTCTC TGTCACAGAG
ACCACAGACA AAGTTATACA CAACAGCATG TGTATAGCTG AAATTGACTT AATTCCTCGA
GATAGGCCGT TTGTATGTGC ACCCTCTTCA AAAACTGGGT CTGTGACTAC AACATATTGC
TGCAATCAGG ACCATTGCAA TAAAATAGAA CTTCCAACTA CTGGCCCTTT TTCAGTAAAG
TCATCACCTG GCCTTGGTCC TGTGGAACTG GCAGCTGTCA TTGCTGGACC AGTGTGCTTC
GTCTGCATCT CACTCATGTT GATGGTCTAT ATCTGCCACA ACCGCACTGT CATTCACCAT
CGAGTGCCAA ATGAAGAGGA CCCTTCATTA GATCGCCCTT TTATTTCAGA GGGTACTACG
TTGAAAGACT TAATTTATGA TATGACAACG TCAGGTTCTG GCTCAGGTTT ACCATTGCTT
GTTCAGAGAA CAATTGCGAG AACTATTGTG TTACAAGAAA GCATTGGCAA AGGTCGATTT
GGAGAAGTTT GGAGAGGAAA GTGGCGGGGA GAAGAAGTTG CTGTTAAGAT ATTCTCCTCT
AGAGAAGAAC GTTCGTGGTT CCGTGAGGCA GAGATTTATC AAACTGTAAT GTTACGTCAT
GAAAACATCC TGGGATTTAT AGCAGCAGAC AATAAAGACA ATGGTACTTG GACTCAGCTC
TGGTTGGTGT CAGATTATCA TGAGCATGGA TCCCTTTTTG ATTACTTAAA CAGATACACA
GTTACTGTGG AAGGAATGAT AAAACTTGCT CTGTCCACGG CGAGCGGTCT TGCCCATCTT
CACATGGAGA TTGTTGGTAC CCAAGGAAAG CCAGCCATTG CTCATAGAGA TTTGAAATCA
AAGAATATCT TGGTAAAGAA GAATGGAACT TGCTGTATTG CAGACTTAGG ACTGGCAGTA
AGACATGATT CAGCCACAGA TACCATTGAT ATTGCTCCAA ACCACAGAGT GGGAACAAAA
AGGTACATGG CCCCTGAAGT TCTCGATGAT TCCATAAATA TGAAACATTT TGAATCCTTC
AAACGTGCTG ACATCTATGC AATGGGCTTA GTATTCTGGG AAATTGCTCG ACGATGTTCC
ATTGGTGGAA TTCATGAAGA TTACCAACTG CCTTATTATG ATCTTGTACC TTCTGACCCA
TCAGTTGAAG AAATGAGAAA AGTTGTTTGT GAACAGAAGT TAAGGCCAAA TATCCCAAAC
AGATGGCAGA GCTGTGAAGC CTTGAGAGTA ATGGCTAAAA TTATGAGAGA ATGTTGGTAT
GCCAATGGAG CAGCTAGGCT TACAGCATTG CGGATTAAGA AAACATTATC GCAACTCAGT
CAACAGGAAG GCATCAAAAT GTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

 
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