The following TGM1 gene sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TGM1 gene which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
||ORF Nucleotide Sequence (Length: 2454bp)
||pcDNA3.1+/C-(K)DYK or customized vector
|Tag on pcDNA3.1+/C-(K)DYK
||C terminal DYKDDDDK tags
|ORF Insert Method
||CloneEZ® Seamless cloning technology
||Homo sapiens (human)
||protein-glutamine gamma-glutamyltransferase K
||REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from DA437895.1, BC034699.1 and
This sequence is a reference standard in the RefSeqGene project.
On Jul 20, 2006 this sequence version replaced gi:4507474.
Summary: The protein encoded by this gene is a membrane protein
that catalyzes the addition of an alkyl group from an akylamine to
a glutamine residue of a protein, forming an alkylglutamine in the
protein. This protein alkylation leads to crosslinking of proteins
and catenation of polyamines to proteins. This gene contains either
one or two copies of a 22 nt repeat unit in its 3' UTR. Mutations
in this gene have been associated with autosomal recessive lamellar
ichthyosis (LI) and nonbullous congenital ichthyosiform
erythroderma (NCIE). [provided by RefSeq, Jul 2008].
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
Transcript exon combination :: BC034699.1, AK291350.1 [ECO:0000332]
RNAseq introns :: mixed/partial sample support
COMPLETENESS: complete on the 3' end.