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VCL vinculin [Homo sapiens (human)]

Gene Symbol VCL
Entrez Gene ID 7414
Full Name vinculin
Synonyms CMD1W, CMH15, HEL114, MV, MVCL
General protein information
Preferred Names
vinculin
Names
vinculin
metavinculin
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

10

10q22.2

Summary Vinculin is a cytoskeletal protein associated with cell-cell and cell-matrix junctions, where it is thought to function as one of several interacting proteins involved in anchoring F-actin to the membrane. Defects in VCL are the cause of cardiomyopathy dilated type 1W. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq, Jul 2008]. lac of sum
Disorder MIM:

193065

Disorder Html: Cardiomyopathy, dilated, 1W, 611407 (3); Cardiomyopathy, familial





The following VCL gene sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the VCL gene which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu44532 XM_005270142 PREDICTED: Homo sapiens vinculin (VCL), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 20 Quote Price
OHu44533 XM_005270143 PREDICTED: Homo sapiens vinculin (VCL), transcript variant X2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 20 Quote Price
OHu25616 NM_014000 Homo sapiens vinculin (VCL), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 16 Quote Price
OHu25331 NM_003373 Homo sapiens vinculin (VCL), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 16 Quote Price

*Business Day
**You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.


CloneID OHu44532
Accession Version XM_005270142.1
Sequence Information ORF Nucleotide Sequence (Length: 3408bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product vinculin isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_030059.14) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
3061
3121
3181
3241
3301
3361
ATGCCAGTGT TTCATACGCG CACGATCGAG AGCATCCTGG AGCCGGTGGC ACAGCAGATC 
TCCCACCTGG TGATAATGCA CGAGGAGGGC GAGGTGGACG GCAAAGCCAT TCCTGACCTC
ACCGCGCCCG TGGCCGCCGT GCAGGCGGCC GTCAGCAACC TCGTCCGGGT TGGAAAAGAG
ACTGTTCAAA CCACTGAGGA TCAGATTTTG AAGAGAGATA TGCCACCAGC ATTTATTAAG
GTTGAGAATG CTTGCACCAA GCTTGTCCAG GCAGCTCAGA TGCTTCAGTC AGACCCTTAC
TCAGTGCCTG CTCGAGATTA TCTAATTGAT GGGTCAAGGG GCATCCTCTC TGGAACATCA
GACCTGCTCC TTACCTTCGA TGAGGCTGAG GTCCGTAAAA TTATTAGAGT TTGCAAAGGA
ATTTTGGAAT ATCTTACAGT GGCAGAGGTG GTGGAGACTA TGGAAGATTT GGTCACTTAC
ACAAAGAATC TTGGGCCAGG AATGACTAAG ATGGCCAAGA TGATTGACGA GAGACAGCAG
GAGCTCACTC ACCAGGAGCA CCGAGTGATG TTGGTGAACT CGATGAACAC CGTGAAAGAG
TTGCTGCCAG TTCTCATTTC AGCTATGAAG ATTTTTGTAA CAACTAAAAA CTCAAAAAAC
CAAGGCATAG AGGAAGCTTT AAAAAATCGC AATTTTACTG TAGAAAAAAT GAGTGCTGAA
ATTAATGAGA TAATTCGTGT GTTACAACTC ACCTCTTGGG ATGAAGATGC CTGGGCCAGC
AAGAAGGACA CTGAAGCCAT GAAGAGAGCA TTGGCCTCCA TAGACTCCAA ACTGAACCAG
GCCAAAGGTT GGCTCCGTGA CCCTAGTGCC TCCCCAGGGG ATGCTGGTGA GCAGGCCATC
AGACAGATCT TAGATGAAGC TGGAAAAGTT GGTGAACTCT GTGCAGGCAA AGAACGCAGG
GAGATTCTGG GAACTTGCAA AATGCTAGGG CAGATGACTG ATCAAGTGGC TGACCTCCGT
GCCAGAGGAC AAGGATCCTC ACCGGTGGCC ATGCAGAAAG CTCAGCAGGT ATCTCAGGGT
CTGGATGTGC TCACAGCAAA AGTGGAAAAT GCAGCTCGCA AGCTGGAAGC CATGACCAAC
TCAAAGCAGA GCATTGCAAA GAAGATCGAT GCTGCTCAGA ACTGGCTTGC AGATCCAAAT
GGTGGACCGG AAGGAGAAGA GCAGATTCGA GGTGCTTTGG CTGAAGCTCG GAAAATAGCA
GAATTATGTG ATGATCCTAA AGAAAGAGAT GACATTCTAC GTTCCCTTGG GGAAATATCT
GCTCTGACTT CTAAATTAGC AGATCTACGA AGACAGGGGA AAGGAGATTC TCCAGAGGCT
CGAGCCTTGG CCAAACAGGT GGCCACGGCC CTGCAGAACC TGCAGACCAA AACCAACCGG
GCTGTGGCCA ACAGCAGACC GGCCAAAGCA GCTGTACACC TTGAGGGCAA GATTGAGCAA
GCACAGCGGT GGATTGATAA TCCCACAGTG GATGACCGTG GAGTCGGTCA GGCTGCCATC
CGGGGGCTTG TGGCCGAAGG GCATCGTCTG GCTAATGTTA TGATGGGGCC TTATCGGCAA
GATCTTCTCG CCAAGTGTGA CCGAGTGGAC CAGCTGACAG CCCAGCTGGC TGACCTGGCT
GCCAGAGGGG AAGGGGAGAG TCCTCAGGCA CGAGCACTTG CATCTCAGCT CCAAGACTCC
TTAAAGGATC TAAAAGCTCG GATGCAGGAG GCCATGACTC AGGAAGTGTC AGATGTTTTC
AGCGATACCA CAACTCCCAT CAAGCTGTTG GCAGTGGCAG CCACGGCGCC TCCTGATGCG
CCTAACAGGG AAGAGGTATT TGATGAGAGG GCAGCTAACT TTGAAAACCA TTCAGGAAAG
CTTGGTGCTA CGGCCGAGAA GGCGGCTGCG GTTGGTACTG CTAATAAATC AACAGTGGAA
GGCATTCAGG CCTCAGTGAA GACGGCCCGA GAACTCACAC CCCAGGTGGT CTCGGCTGCT
CGTATCTTAC TTAGGAACCC TGGAAATCAA GCTGCTTATG AACATTTTGA GACCATGAAG
AACCAGTGGA TCGATAATGT TGAAAAAATG ACAGGGCTGG TGGACGAAGC CATTGATACC
AAATCTCTGT TGGATGCTTC AGAAGAAGCA ATTAAAAAAG ACCTGGACAA GTGCAAGGTA
GCTATGGCCA ACATTCAGCC TCAGATGCTG GTTGCTGGGG CAACCAGTAT TGCTCGTCGG
GCCAACCGGA TCCTGCTGGT GGCTAAGAGG GAGGTGGAGA ATTCCGAGGA TCCCAAGTTC
CGTGAGGCTG TGAAAGCTGC CTCTGATGAA TTGAGCAAAA CCATCTCCCC GATGGTGATG
GATGCAAAAG CTGTGGCTGG AAACATTTCC GACCCTGGAC TGCAAAAGAG CTTCCTGGAC
TCAGGATATC GGATCCTGGG AGCTGTGGCC AAGGTCAGAG AAGCCTTCCA ACCTCAGGAG
CCTGACTTCC CGCCGCCTCC ACCAGACCTT GAACAACTCC GACTAACAGA TGAGCTTGCT
CCTCCCAAAC CACCTCTGCC TGAAGGTGAG GTCCCTCCAC CTAGGCCTCC ACCACCAGAG
GAAAAGGATG AAGAGTTCCC TGAGCAGAAG GCCGGGGAGG TGATTAACCA GCCAATGATG
ATGGCTGCCA GACAGCTCCA TGATGAAGCT CGCAAATGGT CCAGCAAGCC GGGCATCCCA
GCCGCTGAGG TGGGTATAGG TGTTGTAGCT GAGGCAGATG CGGCCGATGC TGCTGGCTTC
CCTGTCCCCC CTGACATGGA AGACGATTAC GAACCTGAGC TGCTGTTAAT GCCATCCAAT
CAGCCGGTCA ACCAGCCCAT TCTGGCCGCG GCTCAGTCCT TGCATCGGGA AGCTACCAAG
TGGTCTAGTA AGGGCAATGA CATCATTGCA GCAGCCAAGC GCATGGCTCT GCTGATGGCT
GAGATGTCTC GGCTGGTAAG AGGGGGCAGT GGTACCAAGC GGGCACTCAT TCAGTGTGCC
AAGGACATCG CCAAGGCCTC AGATGAGGTG ACTCGGTTGG CCAAGGAGGT TGCCAAGCAG
TGCACAGATA AACGGATTAG AACCAACCTC TTACAGGTAT GTGAGCGAAT CCCAACCATA
AGCACCCAGC TCAAAATCCT GTCCACAGTG AAGGCCACCA TGCTGGGCCG GACCAACATC
AGTGATGAGG AGTCTGAGCA GGCCACAGAG ATGCTGGTTC ACAATGCCCA GAACCTCATG
CAGTCTGTGA AGGAGACTGT GCGGGAAGCT GAAGCTGCTT CAATCAAAAT TCGAACAGAT
GCTGGATTTA CACTGCGCTG GGTTAGAAAG ACTCCCTGGT ACCAGTAG
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqXP_005270199.1
CDS131..3538
Misc Feature(1)137..3535(+)
Translation
Position Chain Variation Link
19 19 g, t dbSNP:561721542
20 20 a, t dbSNP:529010073
27 27 c, t dbSNP:547337176
34 34 c, t dbSNP:559106123
42 42 a, c dbSNP:763933845
65 65 c, g dbSNP:533231503
67 67 g, t dbSNP:551418878
71 71 c, t dbSNP:370879754
81 81 a, g dbSNP:536893103
94 94 c, t dbSNP:761931436
98 98 c, g dbSNP:368934359
103 103 a, g dbSNP:765704599
105 105 a, g, t dbSNP:750972760
118 118 a, g dbSNP:780482320
122 122 c, g dbSNP:548768602
126 126 c, t dbSNP:754654170
136 136 a, c, g dbSNP:753870747
150 150 g, t dbSNP:764871020
160 160 a, g dbSNP:146750460
161 161 a, g dbSNP:397517240
162 162 a, g dbSNP:777811020
163 163 c, t dbSNP:749266193
164 164 a, g dbSNP:770570643
166 166 c, t dbSNP:774195260
169 169 g, t dbSNP:759312175
175 175 a, g dbSNP:775062250
197 197 a, c dbSNP:776882033
211 211 -, g dbSNP:750937217
211 211 c, t dbSNP:200733607
229 229 c, t dbSNP:568175141
233 233 a, g dbSNP:139329923
244 244 a, t dbSNP:750838330
250 250 c, t dbSNP:144080529
260 260 a, g dbSNP:554116863
288 288 a, g dbSNP:751938777
293 293 g, t dbSNP:755441334
313 313 g, t dbSNP:776787274
314 314 a, g dbSNP:147809878
315 315 c, t dbSNP:769799445
316 316 c, t dbSNP:773335930
319 319 a, g dbSNP:571901910
327 327 a, g dbSNP:762999933
349 349 a, t dbSNP:766886119
354 354 c, t dbSNP:373830664
355 355 a, g dbSNP:759937112
368 368 a, c dbSNP:775532257
385 385 c, t dbSNP:117384664
402 402 a, c dbSNP:749355014
407 407 c, t dbSNP:770946581
412 412 a, g dbSNP:774870551
430 430 c, t dbSNP:71535779
443 443 c, t dbSNP:397517239
469 469 a, g dbSNP:56314318
472 472 c, g dbSNP:775990121
493 493 c, t dbSNP:761174435
496 496 a, g dbSNP:199562976
508 508 c, t dbSNP:148966602
514 514 a, g dbSNP:756746383
526 526 c, t dbSNP:761378361
534 534 c, t dbSNP:373744314
542 542 g, t dbSNP:749922427
554 554 c, t dbSNP:762497815
583 583 c, g dbSNP:766271456
585 585 a, g dbSNP:751528827
587 587 a, c dbSNP:376921881
602 602 g, t dbSNP:371583362
612 612 c, t dbSNP:376226543
613 613 a, g dbSNP:754020959
622 622 g, t dbSNP:143702799
628 628 a, g dbSNP:779332764
634 634 a, g dbSNP:779240568
638 638 a, g dbSNP:750701726
641 641 a, g dbSNP:758498714
657 657 a, g dbSNP:573623641
658 658 c, t dbSNP:746453891
670 670 a, g dbSNP:769031743
678 678 c, t dbSNP:781748134
685 685 a, g dbSNP:748428678
692 692 c, t dbSNP:397517244
693 693 a, g dbSNP:770173689
695 695 a, c, g, t dbSNP:151045204
701 701 c, t dbSNP:370334093
712 712 a, g dbSNP:773725513
715 715 a, g dbSNP:759141517
720 720 c, t dbSNP:189242810
721 721 c, t dbSNP:199960157
722 722 a, g, t dbSNP:760340545
725 725 -, a dbSNP:777492997
740 740 c, g dbSNP:727504585
751 751 a, t dbSNP:750610030
755 755 a, g, t dbSNP:144683137
756 756 a, t dbSNP:751243981
765 765 c, t dbSNP:754962481
766 766 c, t dbSNP:767648679
771 771 c, t dbSNP:753078158
779 779 a, g dbSNP:727505216
783 783 -, a dbSNP:770713697
789 789 -, a dbSNP:397517245
790 790 c, t dbSNP:56264452
806 806 a, g dbSNP:146910007
810 810 -, a dbSNP:776583302
818 818 c, t dbSNP:139312390
819 819 a, g dbSNP:749628307
825 825 a, t dbSNP:200956572
830 830 c, g dbSNP:17853882
831 831 c, t dbSNP:757655707
834 834 a, g dbSNP:778383501
841 841 a, g dbSNP:61731175
849 849 a, c dbSNP:745549651
853 853 c, t dbSNP:771420978
864 864 c, t dbSNP:779616187
867 867 a, g dbSNP:746577068
869 869 a, g dbSNP:545372383
876 876 a, g dbSNP:768692845
886 886 c, t dbSNP:776751791
898 898 c, t dbSNP:56413529
904 904 a, g dbSNP:769652323
910 910 c, t dbSNP:774377548
920 920 a, t dbSNP:142233726
921 921 c, g dbSNP:150443513
922 922 c, t dbSNP:538002543
937 937 a, g dbSNP:556334319
939 939 c, g dbSNP:762710405
940 940 a, t dbSNP:772312532
941 941 c, t dbSNP:727505339
942 942 c, t dbSNP:760702936
945 945 c, t dbSNP:764174200
950 950 a, c dbSNP:754279934
951 951 c, t dbSNP:762380935
956 956 g, t dbSNP:765726337
960 960 a, g dbSNP:750778483
962 962 a, c dbSNP:71579353
977 977 g, t dbSNP:766091503
986 986 c, t dbSNP:757517552
987 987 a, g dbSNP:397517246
996 996 c, g dbSNP:138270989
1008 1008 a, g dbSNP:763330709
1021 1021 g, t dbSNP:766861514
1056 1056 a, t dbSNP:751189080
1061 1061 a, g dbSNP:754672134
1071 1071 a, g dbSNP:761311084
1074 1074 a, c dbSNP:767337343
1078 1078 a, c dbSNP:61731180
1080 1080 a, c dbSNP:143944164
1082 1082 c, g dbSNP:777722727
1085 1085 c, t dbSNP:397517247
1098 1098 -, g dbSNP:35755339
1101 1101 a, g dbSNP:757012350
1130 1130 a, g dbSNP:778677392
1139 1139 a, g dbSNP:565546734
1140 1140 c, t dbSNP:768848417
1146 1146 -, cc dbSNP:773392439
1147 1147 c, t dbSNP:776878173
1148 1148 c, t dbSNP:759961842
1151 1151 a, g dbSNP:372655194
1152 1152 c, t dbSNP:374928228
1163 1163 a, g dbSNP:757177287
1164 1164 c, g dbSNP:778875353
1172 1172 c, t dbSNP:566961713
1173 1173 c, t dbSNP:148619523
1174 1174 a, c, g dbSNP:373079313
1178 1178 a, g dbSNP:769843518
1179 1179 c, t dbSNP:777709634
1182 1182 c, t dbSNP:749442700
1183 1183 a, g dbSNP:771542436
1199 1199 a, g dbSNP:141503166
1237 1237 a, g dbSNP:764989536
1247 1247 c, t dbSNP:770954415
1248 1248 a, g, t dbSNP:377289804
1254 1254 c, t dbSNP:772585321
1266 1266 c, t dbSNP:775148594
1290 1290 a, g dbSNP:200342284
1297 1297 c, t dbSNP:370852950
1298 1298 a, g dbSNP:776129187
1300 1300 c, t dbSNP:377730275
1303 1303 c, t dbSNP:201459260
1325 1325 c, t dbSNP:201528612
1328 1328 a, c, g dbSNP:377228795
1331 1331 g, t dbSNP:201361282
1338 1338 c, t dbSNP:766393966
1339 1339 a, g dbSNP:779265817
1340 1340 c, g dbSNP:757770090
1342 1342 -, agg dbSNP:765447405
1348 1348 a, g dbSNP:572338868
1358 1358 c, g, t dbSNP:202005455
1369 1369 a, g dbSNP:757353180
1370 1370 a, g dbSNP:146278697
1379 1379 c, t dbSNP:746004026
1380 1380 a, g dbSNP:758811315
1381 1381 a, g dbSNP:780652072
1386 1386 c, t dbSNP:147566238
1391 1391 a, g dbSNP:769092143
1393 1393 a, g dbSNP:776212479
1396 1396 a, g dbSNP:747806207
1401 1401 a, g dbSNP:769504902
1408 1408 c, t dbSNP:397517233
1420 1420 a, t dbSNP:139371702
1423 1423 c, t dbSNP:576271894
1425 1425 g, t dbSNP:766192312
1427 1427 c, g, t dbSNP:144146254
1429 1429 a, g dbSNP:150993814
1430 1430 c, t dbSNP:139559937
1431 1431 a, g dbSNP:754046223
1434 1434 a, c dbSNP:757541730
1442 1442 a, g dbSNP:765607137
1445 1445 a, g, t dbSNP:150016624
1450 1450 c, t dbSNP:71579355
1462 1462 c, t dbSNP:142350240
1467 1467 c, t dbSNP:747568915
1470 1470 c, g dbSNP:727504675
1479 1479 g, t dbSNP:755234443
1480 1480 a, g dbSNP:781535174
1481 1481 a, c dbSNP:142128712
1488 1488 g, t dbSNP:755499383
1509 1509 c, g dbSNP:781698782
1512 1512 a, c, g dbSNP:753026034
1522 1522 c, t dbSNP:777352656
1523 1523 a, c, g dbSNP:200710859
1527 1527 a, c dbSNP:770278621
1535 1535 a, g dbSNP:778480026
1536 1536 c, t dbSNP:147957747
1537 1537 a, g dbSNP:772104870
1540 1540 c, t dbSNP:2229507
1549 1549 c, t dbSNP:760497437
1555 1555 g, t dbSNP:772617847
1557 1557 a, c dbSNP:768588739
1560 1560 a, g dbSNP:773244741
1566 1566 a, g dbSNP:763235691
1568 1568 c, t dbSNP:369055603
1578 1578 c, g dbSNP:531596507
1582 1582 c, t dbSNP:751634052
1585 1585 c, t dbSNP:759571842
1591 1591 a, g dbSNP:767968937
1609 1609 c, g dbSNP:753220379
1623 1623 c, t dbSNP:572757800
1635 1635 a, g dbSNP:778114927
1637 1637 c, t dbSNP:754221616
1638 1638 a, g dbSNP:201808867
1639 1639 a, g dbSNP:2228373
1644 1644 c, t dbSNP:745343813
1660 1660 a, g dbSNP:564882287
1667 1667 c, t dbSNP:781079975
1668 1668 a, g, t dbSNP:367568441
1675 1675 c, t dbSNP:7904077
1688 1688 a, c dbSNP:141033098
1690 1690 a, c dbSNP:150120464
1691 1691 c, t dbSNP:377722209
1692 1692 a, g, t dbSNP:757009736
1696 1696 c, g dbSNP:747932867
1705 1705 c, t dbSNP:138566234
1708 1708 a, c dbSNP:548487697
1711 1711 a, g dbSNP:141544441
1716 1716 a, g dbSNP:746095066
1730 1730 a, g dbSNP:772348187
1732 1732 c, g dbSNP:775532849
1739 1739 a, c, t dbSNP:370058111
1740 1740 a, c dbSNP:200624351
1746 1746 a, g dbSNP:566596830
1753 1753 g, t dbSNP:533622785
1754 1754 c, g dbSNP:370229150
1758 1758 c, t dbSNP:758114136
1759 1759 c, t dbSNP:150402791
1760 1760 a, g, t dbSNP:745748680
1772 1772 c, t dbSNP:397517234
1773 1773 a, g dbSNP:748044427
1777 1777 a, g dbSNP:755868550
1801 1801 c, t dbSNP:777424874
1804 1804 c, t dbSNP:137877092
1819 1819 a, g dbSNP:772258363
1823 1823 c, g, t dbSNP:374538684
1830 1830 g, t dbSNP:376620290
1846 1846 -, a dbSNP:779488376
1849 1849 g, t dbSNP:189781480
1851 1851 c, g dbSNP:777130723
1854 1854 c, t dbSNP:574643494
1889 1889 c, t dbSNP:770778046
1890 1890 a, g dbSNP:774076269
1891 1891 a, c, g dbSNP:759103182
1895 1895 c, t dbSNP:727504381
1898 1898 a, g dbSNP:187247459
1921 1921 a, c dbSNP:199582103
1925 1925 a, g dbSNP:397517235
1926 1926 c, t dbSNP:763977443
1931 1931 a, c dbSNP:397517236
1940 1940 a, c, g, t dbSNP:753788366
1943 1943 a, g dbSNP:754470470
1949 1949 a, g dbSNP:750293810
1963 1963 a, c dbSNP:755136660
1971 1971 c, g dbSNP:781520177
1973 1973 a, t dbSNP:142695754
1974 1974 c, t dbSNP:748140302
1975 1975 a, g dbSNP:144117013
1977 1977 c, t dbSNP:148669762
1978 1978 a, g dbSNP:749812890
1989 1989 c, t dbSNP:771628544
1994 1994 a, g dbSNP:374309823
1996 1996 c, g dbSNP:746293391
1998 1998 a, g dbSNP:771590749
1999 1999 a, g dbSNP:372402817
2004 2004 a, t dbSNP:775238596
2018 2018 a, g dbSNP:748683598
2021 2021 a, g dbSNP:727503739
2023 2023 a, t dbSNP:774940704
2034 2034 a, c dbSNP:746660046
2040 2040 a, g dbSNP:71579374
2041 2041 c, t dbSNP:372696553
2048 2048 a, c dbSNP:761356586
2054 2054 a, g dbSNP:765123545
2061 2061 c, t dbSNP:150643310
2065 2065 c, t dbSNP:762594014
2066 2066 a, g dbSNP:766197411
2070 2070 a, c dbSNP:751374648
2073 2073 c, t dbSNP:534449109
2080 2080 a, g dbSNP:200168992
2084 2084 a, g dbSNP:753936921
2089 2089 c, t dbSNP:757443298
2102 2102 a, g dbSNP:779238311
2103 2103 c, t dbSNP:750946056
2106 2106 c, t dbSNP:372691803
2126 2126 c, g dbSNP:780455788
2134 2134 a, g dbSNP:747424067
2137 2137 a, c dbSNP:768269673
2138 2138 c, t dbSNP:780856981
2139 2139 a, g, t dbSNP:759771302
2149 2149 a, g dbSNP:773292837
2155 2155 a, g dbSNP:772952515
2158 2158 a, g dbSNP:140766884
2161 2161 c, g, t dbSNP:528539468
2163 2163 c, t dbSNP:770869561
2168 2168 g, t dbSNP:375392559
2171 2171 c, t dbSNP:759356162
2179 2179 a, t dbSNP:565398652
2183 2183 a, g dbSNP:730880249
2224 2224 c, t dbSNP:775493699
2227 2227 a, g dbSNP:762082739
2235 2235 a, c dbSNP:765427693
2270 2270 a, g dbSNP:374737519
2274 2274 a, g dbSNP:748791215
2275 2275 c, t dbSNP:373790383
2287 2287 -, t dbSNP:765390858
2293 2293 a, g dbSNP:778936265
2315 2315 a, g dbSNP:144717954
2323 2323 c, t dbSNP:749070899
2339 2339 a, g dbSNP:768613265
2352 2352 c, t dbSNP:775403638
2362 2362 c, g dbSNP:376448550
2370 2370 a, c dbSNP:746821947
2374 2374 c, g dbSNP:770019329
2398 2398 c, t dbSNP:147887754
2401 2401 g, t dbSNP:773331333
2406 2406 a, c, g dbSNP:371970354
2408 2408 a, c, t dbSNP:774477633
2418 2418 a, g dbSNP:540039788
2438 2438 a, g dbSNP:566257885
2439 2439 a, g dbSNP:774113930
2455 2455 c, t dbSNP:202184524
2458 2458 a, g dbSNP:763751776
2471 2471 c, t dbSNP:753445972
2482 2482 a, g dbSNP:558040780
2486 2486 a, g dbSNP:778554042
2498 2498 a, g dbSNP:745419923
2500 2500 a, g dbSNP:758380381
2501 2501 c, t dbSNP:780172945
2503 2503 a, g dbSNP:746772109
2504 2504 a, c dbSNP:552164143
2511 2511 a, c dbSNP:773421444
2519 2519 c, t dbSNP:749471739
2521 2521 a, g dbSNP:767809
2522 2522 a, g dbSNP:774388320
2526 2526 c, t dbSNP:759650076
2528 2528 a, g dbSNP:150069336
2529 2529 c, t dbSNP:775881749
2534 2534 a, g dbSNP:761040547
2536 2536 a, g dbSNP:764369922
2540 2540 a, c, g dbSNP:754294941
2547 2547 c, t dbSNP:765022798
2551 2551 a, g dbSNP:538142998
2560 2560 a, c, t dbSNP:183739128
2561 2561 a, g dbSNP:751458490
2565 2565 c, g dbSNP:568363284
2571 2571 c, t dbSNP:762488785
2575 2575 a, g dbSNP:765806176
2577 2577 a, g dbSNP:373010557
2578 2578 c, g dbSNP:754845064
2587 2587 a, g dbSNP:781226887
2593 2593 a, g dbSNP:752445640
2597 2597 c, t dbSNP:755922886
2600 2600 c, t dbSNP:779047174
2601 2601 a, g dbSNP:759202535
2605 2605 c, g dbSNP:140381835
2634 2634 c, g dbSNP:779983509
2648 2648 a, g dbSNP:747152761
2650 2650 a, g dbSNP:769004916
2653 2653 g, t dbSNP:777218777
2654 2654 c, g dbSNP:150385900
2661 2661 c, t dbSNP:764302249
2664 2664 c, t dbSNP:145393322
2672 2672 c, t dbSNP:372711612
2690 2690 c, g dbSNP:766109034
2693 2693 a, c, t dbSNP:551463686
2709 2709 c, t dbSNP:767056229
2712 2712 c, t dbSNP:765475780
2728 2728 a, g dbSNP:760592370
2734 2734 a, c dbSNP:764067327
2748 2748 c, t dbSNP:753591066
2752 2752 a, t dbSNP:757098704
2758 2758 g, t dbSNP:766455990
2763 2763 c, t dbSNP:570362710
2782 2782 a, c dbSNP:752902180
2785 2785 a, g dbSNP:371187988
2788 2788 c, t dbSNP:149196315
2803 2803 c, g, t dbSNP:748291846
2805 2805 c, g dbSNP:727503740
2815 2815 a, t dbSNP:778451778
2817 2817 a, c dbSNP:749563819
2830 2830 g, t dbSNP:771337725
2841 2841 c, g dbSNP:779345627
2848 2848 c, t dbSNP:778360845
2852 2852 g, t dbSNP:745528944
2861 2861 c, g dbSNP:375595550
2875 2875 c, t dbSNP:774958206
2879 2879 c, t dbSNP:776188207
2880 2880 c, t dbSNP:143321584
2881 2881 a, g dbSNP:761794669
2886 2886 c, t dbSNP:769665651
2893 2893 c, t dbSNP:138594604
2894 2894 a, g dbSNP:764278411
2895 2895 c, t dbSNP:375254227
2896 2896 c, t dbSNP:767803482
2907 2907 -, taggtg dbSNP:757018106
2917 2917 a, c dbSNP:752985431
2919 2919 c, t dbSNP:368113653
2920 2920 g, t dbSNP:764266671
2929 2929 c, t dbSNP:140308982
2931 2931 c, t dbSNP:550741064
2932 2932 a, g dbSNP:199507346
2933 2933 a, g dbSNP:750750224
2934 2934 c, t dbSNP:16931179
2935 2935 c, t dbSNP:372381809
2936 2936 a, g dbSNP:746658025
2940 2940 c, t dbSNP:754681045
2947 2947 c, g dbSNP:2131956
2956 2956 c, t dbSNP:747647927
2958 2958 a, c dbSNP:375627694
2960 2960 c, g dbSNP:71579375
2961 2961 -, ct dbSNP:781036800
2962 2962 c, t dbSNP:200480221
2962 2962 -, t dbSNP:750347797
2966 2966 a, g dbSNP:773050457
2974 2974 c, t dbSNP:566296495
2980 2980 c, t dbSNP:770857763
2984 2984 c, t dbSNP:774356864
2985 2985 c, g dbSNP:368570586
2988 2988 a, g, t dbSNP:367805257
2994 2994 -, tgt dbSNP:541909633
2995 2995 -, gtt dbSNP:397517237
2996 2996 a, t dbSNP:776741969
2999 2999 a, c dbSNP:761830073
3000 3000 g, t dbSNP:765717598
3007 3007 c, t dbSNP:750897774
3008 3008 a, c, g dbSNP:758969419
3009 3009 a, g dbSNP:751966871
3015 3015 a, c, t dbSNP:754591130
3016 3016 a, c, g dbSNP:747640704
3020 3020 a, g dbSNP:777702397
3026 3026 c, t dbSNP:749236817
3037 3037 c, t dbSNP:558112511
3038 3038 a, g dbSNP:199751261
3039 3039 a, c, t dbSNP:534101808
3041 3041 c, g dbSNP:776730962
3042 3042 c, g dbSNP:761884758
3047 3047 a, t dbSNP:765226093
3056 3056 c, t dbSNP:121917776
3057 3057 a, g, t dbSNP:767325003
3102 3102 c, t dbSNP:150595117
3108 3108 a, g dbSNP:759883391
3112 3112 c, t dbSNP:767772108
3140 3140 c, t dbSNP:753166628
3147 3147 g, t dbSNP:760225820
3159 3159 g, t dbSNP:763848963
3166 3166 c, t dbSNP:537877002
3171 3171 -, ggcac dbSNP:748708754
3184 3184 c, g, t dbSNP:756849548
3199 3199 c, t dbSNP:138619320
3200 3200 a, g dbSNP:758417927
3223 3223 g, t dbSNP:779689114
3224 3224 c, t dbSNP:746857871
3225 3225 a, g dbSNP:397517238
3235 3235 a, g dbSNP:373584575
3238 3238 a, g dbSNP:543501836
3247 3247 c, g dbSNP:749303911
3248 3248 c, t dbSNP:727503741
3293 3293 a, g dbSNP:182756080
3294 3294 a, g dbSNP:777193704
3296 3296 c, t dbSNP:727505159
3313 3313 c, t dbSNP:149602433
3319 3319 a, g dbSNP:761534024
3322 3322 c, t dbSNP:765020779
3349 3349 c, t dbSNP:201015523
3355 3355 a, g dbSNP:772554405
3359 3359 c, t dbSNP:397517241
3360 3360 a, g dbSNP:766167366
3369 3369 c, t dbSNP:727503742
3370 3370 c, t dbSNP:201526599
3377 3377 -, gag dbSNP:774357613
3397 3397 a, g dbSNP:755500343
3400 3400 c, g dbSNP:149300310
3412 3412 c, t dbSNP:748463679
3438 3438 c, t dbSNP:770283441
3452 3452 c, t dbSNP:778062413
3460 3460 c, t dbSNP:397517242
3466 3466 c, t dbSNP:147415627
3473 3473 a, g dbSNP:773883360
3481 3481 a, t dbSNP:759081621
3496 3496 a, c dbSNP:771949807
3506 3506 c, t dbSNP:373317423
3508 3508 a, c dbSNP:12573090
3526 3526 c, t dbSNP:760396103
3550 3550 a, t dbSNP:763946964
3555 3555 a, g dbSNP:753624420
3563 3563 c, g dbSNP:763202783
3585 3585 c, g dbSNP:766538575
3592 3592 g, t dbSNP:751639273
3596 3596 c, t dbSNP:755118759
3602 3602 c, t dbSNP:781735621
3645 3645 a, t dbSNP:76086805
3657 3657 c, t dbSNP:181553856
3660 3660 a, g dbSNP:751644253
3670 3670 c, g dbSNP:561614915
3681 3681 -, a dbSNP:756151016
3686 3686 a, g dbSNP:528724911
3750 3750 a, c dbSNP:757322860
3760 3760 a, g dbSNP:187329763
3787 3787 c, t dbSNP:143302346
3830 3830 c, g dbSNP:77295081
3834 3834 c, t dbSNP:781526146
3837 3837 a, c dbSNP:79597107
3851 3851 a, c dbSNP:568476628
3857 3857 g, t dbSNP:535835231
3891 3891 -, ct dbSNP:144115212
3922 3922 c, t dbSNP:548234725
3926 3926 a, c dbSNP:1804892
4071 4071 g, t dbSNP:566737975
4081 4081 a, g dbSNP:755916187
4096 4096 a, g dbSNP:192181239
4114 4114 a, g dbSNP:558682607
4139 4139 c, t dbSNP:578158126
4144 4144 c, t dbSNP:368948216
4184 4184 c, g dbSNP:41280414
4190 4190 c, t dbSNP:79816413
4236 4236 a, c dbSNP:182637339
4266 4266 a, c dbSNP:187721829
4274 4274 a, g dbSNP:774201697
4295 4295 c, t dbSNP:561449879
4340 4340 c, t dbSNP:573450784
4367 4367 -, g dbSNP:71021590
4402 4402 c, t dbSNP:536381894
4464 4464 a, g dbSNP:778644714
4525 4525 c, t dbSNP:145634601
4526 4526 -, ta dbSNP:16408
4526 4526 a, c dbSNP:78391049
4527 4527 -, at dbSNP:10691440
4528 4528 -, at dbSNP:377692178
4529 4529 -, at dbSNP:397804906
4530 4530 a, c dbSNP:199954386
4532 4532 c, t dbSNP:200520943
4538 4538 c, t dbSNP:540494357
4555 4555 a, g dbSNP:771598058
4575 4575 a, t dbSNP:1049456
4579 4579 -, c dbSNP:36124091
4629 4629 c, t dbSNP:572703269
4654 4654 -, t dbSNP:751412447
4661 4661 -, ag dbSNP:780897563
4720 4720 g, t dbSNP:565092802
4741 4741 a, c dbSNP:149551128
4745 4745 c, t dbSNP:765518427
4768 4768 a, g dbSNP:550301214
4775 4775 c, t dbSNP:562241495
4820 4820 c, t dbSNP:529687198
4836 4836 c, g dbSNP:763283437
4865 4865 -, tatt dbSNP:149589487
4881 4881 -, agta dbSNP:112557979
4881 4881 c, t dbSNP:71535723
4945 4945 a, g dbSNP:566667255
4979 4979 -, aag dbSNP:779904140
5062 5062 a, g dbSNP:764632864
5064 5064 a, g dbSNP:752039786
5067 5067 a, g dbSNP:757363363
5074 5074 c, t dbSNP:534064723
5106 5106 c, t dbSNP:552401207
5117 5117 c, t dbSNP:747049435
5122 5122 a, t dbSNP:703258
5174 5174 c, t dbSNP:144240368
5197 5197 c, t dbSNP:1804893
5241 5241 -, aaaga dbSNP:140046305
5245 5245 c, g dbSNP:756405514
5248 5248 -, agaaa dbSNP:377566645
5255 5255 g, t dbSNP:780201805
5269 5269 a, g dbSNP:1801382
5274 5274 g, t dbSNP:749090680
5289 5289 c, t dbSNP:372750308
5331 5331 c, t dbSNP:575785254
5332 5332 a, g dbSNP:577038840
5350 5350 -, atc dbSNP:151279619
5354 5354 -, tca dbSNP:35726593
5361 5361 a, g dbSNP:8255
5380 5380 -, aa, aaa dbSNP:370456912
5381 5381 -, aa dbSNP:386371830
5385 5385 a, c dbSNP:1049613
5387 5387 -, c dbSNP:200756813
5387 5387 a, c dbSNP:3829205
5388 5388 a, c dbSNP:3189804
5391 5391 a, c dbSNP:554923257
5392 5392 -, c dbSNP:201189785
5392 5392 a, c dbSNP:3829204
5400 5400 -, aa dbSNP:3037361
5400 5400 -, a dbSNP:59061551
5426 5426 a, c dbSNP:1049614
5429 5429 a, g dbSNP:529702817
5459 5459 c, t dbSNP:540882056
5486 5486 g, t dbSNP:559715454
5487 5487 c, g dbSNP:541995253

Target ORF information:

RefSeq Version XM_005270142
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens vinculin (VCL), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_005270142

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
3061
3121
3181
3241
3301
3361
ATGCCAGTGT TTCATACGCG CACGATCGAG AGCATCCTGG AGCCGGTGGC ACAGCAGATC 
TCCCACCTGG TGATAATGCA CGAGGAGGGC GAGGTGGACG GCAAAGCCAT TCCTGACCTC
ACCGCGCCCG TGGCCGCCGT GCAGGCGGCC GTCAGCAACC TCGTCCGGGT TGGAAAAGAG
ACTGTTCAAA CCACTGAGGA TCAGATTTTG AAGAGAGATA TGCCACCAGC ATTTATTAAG
GTTGAGAATG CTTGCACCAA GCTTGTCCAG GCAGCTCAGA TGCTTCAGTC AGACCCTTAC
TCAGTGCCTG CTCGAGATTA TCTAATTGAT GGGTCAAGGG GCATCCTCTC TGGAACATCA
GACCTGCTCC TTACCTTCGA TGAGGCTGAG GTCCGTAAAA TTATTAGAGT TTGCAAAGGA
ATTTTGGAAT ATCTTACAGT GGCAGAGGTG GTGGAGACTA TGGAAGATTT GGTCACTTAC
ACAAAGAATC TTGGGCCAGG AATGACTAAG ATGGCCAAGA TGATTGACGA GAGACAGCAG
GAGCTCACTC ACCAGGAGCA CCGAGTGATG TTGGTGAACT CGATGAACAC CGTGAAAGAG
TTGCTGCCAG TTCTCATTTC AGCTATGAAG ATTTTTGTAA CAACTAAAAA CTCAAAAAAC
CAAGGCATAG AGGAAGCTTT AAAAAATCGC AATTTTACTG TAGAAAAAAT GAGTGCTGAA
ATTAATGAGA TAATTCGTGT GTTACAACTC ACCTCTTGGG ATGAAGATGC CTGGGCCAGC
AAGAAGGACA CTGAAGCCAT GAAGAGAGCA TTGGCCTCCA TAGACTCCAA ACTGAACCAG
GCCAAAGGTT GGCTCCGTGA CCCTAGTGCC TCCCCAGGGG ATGCTGGTGA GCAGGCCATC
AGACAGATCT TAGATGAAGC TGGAAAAGTT GGTGAACTCT GTGCAGGCAA AGAACGCAGG
GAGATTCTGG GAACTTGCAA AATGCTAGGG CAGATGACTG ATCAAGTGGC TGACCTCCGT
GCCAGAGGAC AAGGATCCTC ACCGGTGGCC ATGCAGAAAG CTCAGCAGGT ATCTCAGGGT
CTGGATGTGC TCACAGCAAA AGTGGAAAAT GCAGCTCGCA AGCTGGAAGC CATGACCAAC
TCAAAGCAGA GCATTGCAAA GAAGATCGAT GCTGCTCAGA ACTGGCTTGC AGATCCAAAT
GGTGGACCGG AAGGAGAAGA GCAGATTCGA GGTGCTTTGG CTGAAGCTCG GAAAATAGCA
GAATTATGTG ATGATCCTAA AGAAAGAGAT GACATTCTAC GTTCCCTTGG GGAAATATCT
GCTCTGACTT CTAAATTAGC AGATCTACGA AGACAGGGGA AAGGAGATTC TCCAGAGGCT
CGAGCCTTGG CCAAACAGGT GGCCACGGCC CTGCAGAACC TGCAGACCAA AACCAACCGG
GCTGTGGCCA ACAGCAGACC GGCCAAAGCA GCTGTACACC TTGAGGGCAA GATTGAGCAA
GCACAGCGGT GGATTGATAA TCCCACAGTG GATGACCGTG GAGTCGGTCA GGCTGCCATC
CGGGGGCTTG TGGCCGAAGG GCATCGTCTG GCTAATGTTA TGATGGGGCC TTATCGGCAA
GATCTTCTCG CCAAGTGTGA CCGAGTGGAC CAGCTGACAG CCCAGCTGGC TGACCTGGCT
GCCAGAGGGG AAGGGGAGAG TCCTCAGGCA CGAGCACTTG CATCTCAGCT CCAAGACTCC
TTAAAGGATC TAAAAGCTCG GATGCAGGAG GCCATGACTC AGGAAGTGTC AGATGTTTTC
AGCGATACCA CAACTCCCAT CAAGCTGTTG GCAGTGGCAG CCACGGCGCC TCCTGATGCG
CCTAACAGGG AAGAGGTATT TGATGAGAGG GCAGCTAACT TTGAAAACCA TTCAGGAAAG
CTTGGTGCTA CGGCCGAGAA GGCGGCTGCG GTTGGTACTG CTAATAAATC AACAGTGGAA
GGCATTCAGG CCTCAGTGAA GACGGCCCGA GAACTCACAC CCCAGGTGGT CTCGGCTGCT
CGTATCTTAC TTAGGAACCC TGGAAATCAA GCTGCTTATG AACATTTTGA GACCATGAAG
AACCAGTGGA TCGATAATGT TGAAAAAATG ACAGGGCTGG TGGACGAAGC CATTGATACC
AAATCTCTGT TGGATGCTTC AGAAGAAGCA ATTAAAAAAG ACCTGGACAA GTGCAAGGTA
GCTATGGCCA ACATTCAGCC TCAGATGCTG GTTGCTGGGG CAACCAGTAT TGCTCGTCGG
GCCAACCGGA TCCTGCTGGT GGCTAAGAGG GAGGTGGAGA ATTCCGAGGA TCCCAAGTTC
CGTGAGGCTG TGAAAGCTGC CTCTGATGAA TTGAGCAAAA CCATCTCCCC GATGGTGATG
GATGCAAAAG CTGTGGCTGG AAACATTTCC GACCCTGGAC TGCAAAAGAG CTTCCTGGAC
TCAGGATATC GGATCCTGGG AGCTGTGGCC AAGGTCAGAG AAGCCTTCCA ACCTCAGGAG
CCTGACTTCC CGCCGCCTCC ACCAGACCTT GAACAACTCC GACTAACAGA TGAGCTTGCT
CCTCCCAAAC CACCTCTGCC TGAAGGTGAG GTCCCTCCAC CTAGGCCTCC ACCACCAGAG
GAAAAGGATG AAGAGTTCCC TGAGCAGAAG GCCGGGGAGG TGATTAACCA GCCAATGATG
ATGGCTGCCA GACAGCTCCA TGATGAAGCT CGCAAATGGT CCAGCAAGCC GGGCATCCCA
GCCGCTGAGG TGGGTATAGG TGTTGTAGCT GAGGCAGATG CGGCCGATGC TGCTGGCTTC
CCTGTCCCCC CTGACATGGA AGACGATTAC GAACCTGAGC TGCTGTTAAT GCCATCCAAT
CAGCCGGTCA ACCAGCCCAT TCTGGCCGCG GCTCAGTCCT TGCATCGGGA AGCTACCAAG
TGGTCTAGTA AGGGCAATGA CATCATTGCA GCAGCCAAGC GCATGGCTCT GCTGATGGCT
GAGATGTCTC GGCTGGTAAG AGGGGGCAGT GGTACCAAGC GGGCACTCAT TCAGTGTGCC
AAGGACATCG CCAAGGCCTC AGATGAGGTG ACTCGGTTGG CCAAGGAGGT TGCCAAGCAG
TGCACAGATA AACGGATTAG AACCAACCTC TTACAGGTAT GTGAGCGAAT CCCAACCATA
AGCACCCAGC TCAAAATCCT GTCCACAGTG AAGGCCACCA TGCTGGGCCG GACCAACATC
AGTGATGAGG AGTCTGAGCA GGCCACAGAG ATGCTGGTTC ACAATGCCCA GAACCTCATG
CAGTCTGTGA AGGAGACTGT GCGGGAAGCT GAAGCTGCTT CAATCAAAAT TCGAACAGAT
GCTGGATTTA CACTGCGCTG GGTTAGAAAG ACTCCCTGGT ACCAGTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu44533
Accession Version XM_005270143.1
Sequence Information ORF Nucleotide Sequence (Length: 3204bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product vinculin isoform X2
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_030059.14) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
3061
3121
3181
ATGCCAGTGT TTCATACGCG CACGATCGAG AGCATCCTGG AGCCGGTGGC ACAGCAGATC 
TCCCACCTGG TGATAATGCA CGAGGAGGGC GAGGTGGACG GCAAAGCCAT TCCTGACCTC
ACCGCGCCCG TGGCCGCCGT GCAGGCGGCC GTCAGCAACC TCGTCCGGGT TGGAAAAGAG
ACTGTTCAAA CCACTGAGGA TCAGATTTTG AAGAGAGATA TGCCACCAGC ATTTATTAAG
GTTGAGAATG CTTGCACCAA GCTTGTCCAG GCAGCTCAGA TGCTTCAGTC AGACCCTTAC
TCAGTGCCTG CTCGAGATTA TCTAATTGAT GGGTCAAGGG GCATCCTCTC TGGAACATCA
GACCTGCTCC TTACCTTCGA TGAGGCTGAG GTCCGTAAAA TTATTAGAGT TTGCAAAGGA
ATTTTGGAAT ATCTTACAGT GGCAGAGGTG GTGGAGACTA TGGAAGATTT GGTCACTTAC
ACAAAGAATC TTGGGCCAGG AATGACTAAG ATGGCCAAGA TGATTGACGA GAGACAGCAG
GAGCTCACTC ACCAGGAGCA CCGAGTGATG TTGGTGAACT CGATGAACAC CGTGAAAGAG
TTGCTGCCAG TTCTCATTTC AGCTATGAAG ATTTTTGTAA CAACTAAAAA CTCAAAAAAC
CAAGGCATAG AGGAAGCTTT AAAAAATCGC AATTTTACTG TAGAAAAAAT GAGTGCTGAA
ATTAATGAGA TAATTCGTGT GTTACAACTC ACCTCTTGGG ATGAAGATGC CTGGGCCAGC
AAGAAGGACA CTGAAGCCAT GAAGAGAGCA TTGGCCTCCA TAGACTCCAA ACTGAACCAG
GCCAAAGGTT GGCTCCGTGA CCCTAGTGCC TCCCCAGGGG ATGCTGGTGA GCAGGCCATC
AGACAGATCT TAGATGAAGC TGGAAAAGTT GGTGAACTCT GTGCAGGCAA AGAACGCAGG
GAGATTCTGG GAACTTGCAA AATGCTAGGG CAGATGACTG ATCAAGTGGC TGACCTCCGT
GCCAGAGGAC AAGGATCCTC ACCGGTGGCC ATGCAGAAAG CTCAGCAGGT ATCTCAGGGT
CTGGATGTGC TCACAGCAAA AGTGGAAAAT GCAGCTCGCA AGCTGGAAGC CATGACCAAC
TCAAAGCAGA GCATTGCAAA GAAGATCGAT GCTGCTCAGA ACTGGCTTGC AGATCCAAAT
GGTGGACCGG AAGGAGAAGA GCAGATTCGA GGTGCTTTGG CTGAAGCTCG GAAAATAGCA
GAATTATGTG ATGATCCTAA AGAAAGAGAT GACATTCTAC GTTCCCTTGG GGAAATATCT
GCTCTGACTT CTAAATTAGC AGATCTACGA AGACAGGGGA AAGGAGATTC TCCAGAGGCT
CGAGCCTTGG CCAAACAGGT GGCCACGGCC CTGCAGAACC TGCAGACCAA AACCAACCGG
GCTGTGGCCA ACAGCAGACC GGCCAAAGCA GCTGTACACC TTGAGGGCAA GATTGAGCAA
GCACAGCGGT GGATTGATAA TCCCACAGTG GATGACCGTG GAGTCGGTCA GGCTGCCATC
CGGGGGCTTG TGGCCGAAGG GCATCGTCTG GCTAATGTTA TGATGGGGCC TTATCGGCAA
GATCTTCTCG CCAAGTGTGA CCGAGTGGAC CAGCTGACAG CCCAGCTGGC TGACCTGGCT
GCCAGAGGGG AAGGGGAGAG TCCTCAGGCA CGAGCACTTG CATCTCAGCT CCAAGACTCC
TTAAAGGATC TAAAAGCTCG GATGCAGGAG GCCATGACTC AGGAAGTGTC AGATGTTTTC
AGCGATACCA CAACTCCCAT CAAGCTGTTG GCAGTGGCAG CCACGGCGCC TCCTGATGCG
CCTAACAGGG AAGAGGTATT TGATGAGAGG GCAGCTAACT TTGAAAACCA TTCAGGAAAG
CTTGGTGCTA CGGCCGAGAA GGCGGCTGCG GTTGGTACTG CTAATAAATC AACAGTGGAA
GGCATTCAGG CCTCAGTGAA GACGGCCCGA GAACTCACAC CCCAGGTGGT CTCGGCTGCT
CGTATCTTAC TTAGGAACCC TGGAAATCAA GCTGCTTATG AACATTTTGA GACCATGAAG
AACCAGTGGA TCGATAATGT TGAAAAAATG ACAGGGCTGG TGGACGAAGC CATTGATACC
AAATCTCTGT TGGATGCTTC AGAAGAAGCA ATTAAAAAAG ACCTGGACAA GTGCAAGGTA
GCTATGGCCA ACATTCAGCC TCAGATGCTG GTTGCTGGGG CAACCAGTAT TGCTCGTCGG
GCCAACCGGA TCCTGCTGGT GGCTAAGAGG GAGGTGGAGA ATTCCGAGGA TCCCAAGTTC
CGTGAGGCTG TGAAAGCTGC CTCTGATGAA TTGAGCAAAA CCATCTCCCC GATGGTGATG
GATGCAAAAG CTGTGGCTGG AAACATTTCC GACCCTGGAC TGCAAAAGAG CTTCCTGGAC
TCAGGATATC GGATCCTGGG AGCTGTGGCC AAGGTCAGAG AAGCCTTCCA ACCTCAGGAG
CCTGACTTCC CGCCGCCTCC ACCAGACCTT GAACAACTCC GACTAACAGA TGAGCTTGCT
CCTCCCAAAC CACCTCTGCC TGAAGGTGAG GTCCCTCCAC CTAGGCCTCC ACCACCAGAG
GAAAAGGATG AAGAGTTCCC TGAGCAGAAG GCCGGGGAGG TGATTAACCA GCCAATGATG
ATGGCTGCCA GACAGCTCCA TGATGAAGCT CGCAAATGGT CCAGCAAGGG CAATGACATC
ATTGCAGCAG CCAAGCGCAT GGCTCTGCTG ATGGCTGAGA TGTCTCGGCT GGTAAGAGGG
GGCAGTGGTA CCAAGCGGGC ACTCATTCAG TGTGCCAAGG ACATCGCCAA GGCCTCAGAT
GAGGTGACTC GGTTGGCCAA GGAGGTTGCC AAGCAGTGCA CAGATAAACG GATTAGAACC
AACCTCTTAC AGGTATGTGA GCGAATCCCA ACCATAAGCA CCCAGCTCAA AATCCTGTCC
ACAGTGAAGG CCACCATGCT GGGCCGGACC AACATCAGTG ATGAGGAGTC TGAGCAGGCC
ACAGAGATGC TGGTTCACAA TGCCCAGAAC CTCATGCAGT CTGTGAAGGA GACTGTGCGG
GAAGCTGAAG CTGCTTCAAT CAAAATTCGA ACAGATGCTG GATTTACACT GCGCTGGGTT
AGAAAGACTC CCTGGTACCA GTAG
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqXP_005270200.1
CDS131..3334
Misc Feature(1)137..3331(+)
Translation
Position Chain Variation Link
19 19 g, t dbSNP:561721542
20 20 a, t dbSNP:529010073
27 27 c, t dbSNP:547337176
34 34 c, t dbSNP:559106123
42 42 a, c dbSNP:763933845
65 65 c, g dbSNP:533231503
67 67 g, t dbSNP:551418878
71 71 c, t dbSNP:370879754
81 81 a, g dbSNP:536893103
94 94 c, t dbSNP:761931436
98 98 c, g dbSNP:368934359
103 103 a, g dbSNP:765704599
105 105 a, g, t dbSNP:750972760
118 118 a, g dbSNP:780482320
122 122 c, g dbSNP:548768602
126 126 c, t dbSNP:754654170
136 136 a, c, g dbSNP:753870747
150 150 g, t dbSNP:764871020
160 160 a, g dbSNP:146750460
161 161 a, g dbSNP:397517240
162 162 a, g dbSNP:777811020
163 163 c, t dbSNP:749266193
164 164 a, g dbSNP:770570643
166 166 c, t dbSNP:774195260
169 169 g, t dbSNP:759312175
175 175 a, g dbSNP:775062250
197 197 a, c dbSNP:776882033
211 211 -, g dbSNP:750937217
211 211 c, t dbSNP:200733607
229 229 c, t dbSNP:568175141
233 233 a, g dbSNP:139329923
244 244 a, t dbSNP:750838330
250 250 c, t dbSNP:144080529
260 260 a, g dbSNP:554116863
288 288 a, g dbSNP:751938777
293 293 g, t dbSNP:755441334
313 313 g, t dbSNP:776787274
314 314 a, g dbSNP:147809878
315 315 c, t dbSNP:769799445
316 316 c, t dbSNP:773335930
319 319 a, g dbSNP:571901910
327 327 a, g dbSNP:762999933
349 349 a, t dbSNP:766886119
354 354 c, t dbSNP:373830664
355 355 a, g dbSNP:759937112
368 368 a, c dbSNP:775532257
385 385 c, t dbSNP:117384664
402 402 a, c dbSNP:749355014
407 407 c, t dbSNP:770946581
412 412 a, g dbSNP:774870551
430 430 c, t dbSNP:71535779
443 443 c, t dbSNP:397517239
469 469 a, g dbSNP:56314318
472 472 c, g dbSNP:775990121
493 493 c, t dbSNP:761174435
496 496 a, g dbSNP:199562976
508 508 c, t dbSNP:148966602
514 514 a, g dbSNP:756746383
526 526 c, t dbSNP:761378361
534 534 c, t dbSNP:373744314
542 542 g, t dbSNP:749922427
554 554 c, t dbSNP:762497815
583 583 c, g dbSNP:766271456
585 585 a, g dbSNP:751528827
587 587 a, c dbSNP:376921881
602 602 g, t dbSNP:371583362
612 612 c, t dbSNP:376226543
613 613 a, g dbSNP:754020959
622 622 g, t dbSNP:143702799
628 628 a, g dbSNP:779332764
634 634 a, g dbSNP:779240568
638 638 a, g dbSNP:750701726
641 641 a, g dbSNP:758498714
657 657 a, g dbSNP:573623641
658 658 c, t dbSNP:746453891
670 670 a, g dbSNP:769031743
678 678 c, t dbSNP:781748134
685 685 a, g dbSNP:748428678
692 692 c, t dbSNP:397517244
693 693 a, g dbSNP:770173689
695 695 a, c, g, t dbSNP:151045204
701 701 c, t dbSNP:370334093
712 712 a, g dbSNP:773725513
715 715 a, g dbSNP:759141517
720 720 c, t dbSNP:189242810
721 721 c, t dbSNP:199960157
722 722 a, g, t dbSNP:760340545
725 725 -, a dbSNP:777492997
740 740 c, g dbSNP:727504585
751 751 a, t dbSNP:750610030
755 755 a, g, t dbSNP:144683137
756 756 a, t dbSNP:751243981
765 765 c, t dbSNP:754962481
766 766 c, t dbSNP:767648679
771 771 c, t dbSNP:753078158
779 779 a, g dbSNP:727505216
783 783 -, a dbSNP:770713697
789 789 -, a dbSNP:397517245
790 790 c, t dbSNP:56264452
806 806 a, g dbSNP:146910007
810 810 -, a dbSNP:776583302
818 818 c, t dbSNP:139312390
819 819 a, g dbSNP:749628307
825 825 a, t dbSNP:200956572
830 830 c, g dbSNP:17853882
831 831 c, t dbSNP:757655707
834 834 a, g dbSNP:778383501
841 841 a, g dbSNP:61731175
849 849 a, c dbSNP:745549651
853 853 c, t dbSNP:771420978
864 864 c, t dbSNP:779616187
867 867 a, g dbSNP:746577068
869 869 a, g dbSNP:545372383
876 876 a, g dbSNP:768692845
886 886 c, t dbSNP:776751791
898 898 c, t dbSNP:56413529
904 904 a, g dbSNP:769652323
910 910 c, t dbSNP:774377548
920 920 a, t dbSNP:142233726
921 921 c, g dbSNP:150443513
922 922 c, t dbSNP:538002543
937 937 a, g dbSNP:556334319
939 939 c, g dbSNP:762710405
940 940 a, t dbSNP:772312532
941 941 c, t dbSNP:727505339
942 942 c, t dbSNP:760702936
945 945 c, t dbSNP:764174200
950 950 a, c dbSNP:754279934
951 951 c, t dbSNP:762380935
956 956 g, t dbSNP:765726337
960 960 a, g dbSNP:750778483
962 962 a, c dbSNP:71579353
977 977 g, t dbSNP:766091503
986 986 c, t dbSNP:757517552
987 987 a, g dbSNP:397517246
996 996 c, g dbSNP:138270989
1008 1008 a, g dbSNP:763330709
1021 1021 g, t dbSNP:766861514
1056 1056 a, t dbSNP:751189080
1061 1061 a, g dbSNP:754672134
1071 1071 a, g dbSNP:761311084
1074 1074 a, c dbSNP:767337343
1078 1078 a, c dbSNP:61731180
1080 1080 a, c dbSNP:143944164
1082 1082 c, g dbSNP:777722727
1085 1085 c, t dbSNP:397517247
1098 1098 -, g dbSNP:35755339
1101 1101 a, g dbSNP:757012350
1130 1130 a, g dbSNP:778677392
1139 1139 a, g dbSNP:565546734
1140 1140 c, t dbSNP:768848417
1146 1146 -, cc dbSNP:773392439
1147 1147 c, t dbSNP:776878173
1148 1148 c, t dbSNP:759961842
1151 1151 a, g dbSNP:372655194
1152 1152 c, t dbSNP:374928228
1163 1163 a, g dbSNP:757177287
1164 1164 c, g dbSNP:778875353
1172 1172 c, t dbSNP:566961713
1173 1173 c, t dbSNP:148619523
1174 1174 a, c, g dbSNP:373079313
1178 1178 a, g dbSNP:769843518
1179 1179 c, t dbSNP:777709634
1182 1182 c, t dbSNP:749442700
1183 1183 a, g dbSNP:771542436
1199 1199 a, g dbSNP:141503166
1237 1237 a, g dbSNP:764989536
1247 1247 c, t dbSNP:770954415
1248 1248 a, g, t dbSNP:377289804
1254 1254 c, t dbSNP:772585321
1266 1266 c, t dbSNP:775148594
1290 1290 a, g dbSNP:200342284
1297 1297 c, t dbSNP:370852950
1298 1298 a, g dbSNP:776129187
1300 1300 c, t dbSNP:377730275
1303 1303 c, t dbSNP:201459260
1325 1325 c, t dbSNP:201528612
1328 1328 a, c, g dbSNP:377228795
1331 1331 g, t dbSNP:201361282
1338 1338 c, t dbSNP:766393966
1339 1339 a, g dbSNP:779265817
1340 1340 c, g dbSNP:757770090
1342 1342 -, agg dbSNP:765447405
1348 1348 a, g dbSNP:572338868
1358 1358 c, g, t dbSNP:202005455
1369 1369 a, g dbSNP:757353180
1370 1370 a, g dbSNP:146278697
1379 1379 c, t dbSNP:746004026
1380 1380 a, g dbSNP:758811315
1381 1381 a, g dbSNP:780652072
1386 1386 c, t dbSNP:147566238
1391 1391 a, g dbSNP:769092143
1393 1393 a, g dbSNP:776212479
1396 1396 a, g dbSNP:747806207
1401 1401 a, g dbSNP:769504902
1408 1408 c, t dbSNP:397517233
1420 1420 a, t dbSNP:139371702
1423 1423 c, t dbSNP:576271894
1425 1425 g, t dbSNP:766192312
1427 1427 c, g, t dbSNP:144146254
1429 1429 a, g dbSNP:150993814
1430 1430 c, t dbSNP:139559937
1431 1431 a, g dbSNP:754046223
1434 1434 a, c dbSNP:757541730
1442 1442 a, g dbSNP:765607137
1445 1445 a, g, t dbSNP:150016624
1450 1450 c, t dbSNP:71579355
1462 1462 c, t dbSNP:142350240
1467 1467 c, t dbSNP:747568915
1470 1470 c, g dbSNP:727504675
1479 1479 g, t dbSNP:755234443
1480 1480 a, g dbSNP:781535174
1481 1481 a, c dbSNP:142128712
1488 1488 g, t dbSNP:755499383
1509 1509 c, g dbSNP:781698782
1512 1512 a, c, g dbSNP:753026034
1522 1522 c, t dbSNP:777352656
1523 1523 a, c, g dbSNP:200710859
1527 1527 a, c dbSNP:770278621
1535 1535 a, g dbSNP:778480026
1536 1536 c, t dbSNP:147957747
1537 1537 a, g dbSNP:772104870
1540 1540 c, t dbSNP:2229507
1549 1549 c, t dbSNP:760497437
1555 1555 g, t dbSNP:772617847
1557 1557 a, c dbSNP:768588739
1560 1560 a, g dbSNP:773244741
1566 1566 a, g dbSNP:763235691
1568 1568 c, t dbSNP:369055603
1578 1578 c, g dbSNP:531596507
1582 1582 c, t dbSNP:751634052
1585 1585 c, t dbSNP:759571842
1591 1591 a, g dbSNP:767968937
1609 1609 c, g dbSNP:753220379
1623 1623 c, t dbSNP:572757800
1635 1635 a, g dbSNP:778114927
1637 1637 c, t dbSNP:754221616
1638 1638 a, g dbSNP:201808867
1639 1639 a, g dbSNP:2228373
1644 1644 c, t dbSNP:745343813
1660 1660 a, g dbSNP:564882287
1667 1667 c, t dbSNP:781079975
1668 1668 a, g, t dbSNP:367568441
1675 1675 c, t dbSNP:7904077
1688 1688 a, c dbSNP:141033098
1690 1690 a, c dbSNP:150120464
1691 1691 c, t dbSNP:377722209
1692 1692 a, g, t dbSNP:757009736
1696 1696 c, g dbSNP:747932867
1705 1705 c, t dbSNP:138566234
1708 1708 a, c dbSNP:548487697
1711 1711 a, g dbSNP:141544441
1716 1716 a, g dbSNP:746095066
1730 1730 a, g dbSNP:772348187
1732 1732 c, g dbSNP:775532849
1739 1739 a, c, t dbSNP:370058111
1740 1740 a, c dbSNP:200624351
1746 1746 a, g dbSNP:566596830
1753 1753 g, t dbSNP:533622785
1754 1754 c, g dbSNP:370229150
1758 1758 c, t dbSNP:758114136
1759 1759 c, t dbSNP:150402791
1760 1760 a, g, t dbSNP:745748680
1772 1772 c, t dbSNP:397517234
1773 1773 a, g dbSNP:748044427
1777 1777 a, g dbSNP:755868550
1801 1801 c, t dbSNP:777424874
1804 1804 c, t dbSNP:137877092
1819 1819 a, g dbSNP:772258363
1823 1823 c, g, t dbSNP:374538684
1830 1830 g, t dbSNP:376620290
1846 1846 -, a dbSNP:779488376
1849 1849 g, t dbSNP:189781480
1851 1851 c, g dbSNP:777130723
1854 1854 c, t dbSNP:574643494
1889 1889 c, t dbSNP:770778046
1890 1890 a, g dbSNP:774076269
1891 1891 a, c, g dbSNP:759103182
1895 1895 c, t dbSNP:727504381
1898 1898 a, g dbSNP:187247459
1921 1921 a, c dbSNP:199582103
1925 1925 a, g dbSNP:397517235
1926 1926 c, t dbSNP:763977443
1931 1931 a, c dbSNP:397517236
1940 1940 a, c, g, t dbSNP:753788366
1943 1943 a, g dbSNP:754470470
1949 1949 a, g dbSNP:750293810
1963 1963 a, c dbSNP:755136660
1971 1971 c, g dbSNP:781520177
1973 1973 a, t dbSNP:142695754
1974 1974 c, t dbSNP:748140302
1975 1975 a, g dbSNP:144117013
1977 1977 c, t dbSNP:148669762
1978 1978 a, g dbSNP:749812890
1989 1989 c, t dbSNP:771628544
1994 1994 a, g dbSNP:374309823
1996 1996 c, g dbSNP:746293391
1998 1998 a, g dbSNP:771590749
1999 1999 a, g dbSNP:372402817
2004 2004 a, t dbSNP:775238596
2018 2018 a, g dbSNP:748683598
2021 2021 a, g dbSNP:727503739
2023 2023 a, t dbSNP:774940704
2034 2034 a, c dbSNP:746660046
2040 2040 a, g dbSNP:71579374
2041 2041 c, t dbSNP:372696553
2048 2048 a, c dbSNP:761356586
2054 2054 a, g dbSNP:765123545
2061 2061 c, t dbSNP:150643310
2065 2065 c, t dbSNP:762594014
2066 2066 a, g dbSNP:766197411
2070 2070 a, c dbSNP:751374648
2073 2073 c, t dbSNP:534449109
2080 2080 a, g dbSNP:200168992
2084 2084 a, g dbSNP:753936921
2089 2089 c, t dbSNP:757443298
2102 2102 a, g dbSNP:779238311
2103 2103 c, t dbSNP:750946056
2106 2106 c, t dbSNP:372691803
2126 2126 c, g dbSNP:780455788
2134 2134 a, g dbSNP:747424067
2137 2137 a, c dbSNP:768269673
2138 2138 c, t dbSNP:780856981
2139 2139 a, g, t dbSNP:759771302
2149 2149 a, g dbSNP:773292837
2155 2155 a, g dbSNP:772952515
2158 2158 a, g dbSNP:140766884
2161 2161 c, g, t dbSNP:528539468
2163 2163 c, t dbSNP:770869561
2168 2168 g, t dbSNP:375392559
2171 2171 c, t dbSNP:759356162
2179 2179 a, t dbSNP:565398652
2183 2183 a, g dbSNP:730880249
2224 2224 c, t dbSNP:775493699
2227 2227 a, g dbSNP:762082739
2235 2235 a, c dbSNP:765427693
2270 2270 a, g dbSNP:374737519
2274 2274 a, g dbSNP:748791215
2275 2275 c, t dbSNP:373790383
2287 2287 -, t dbSNP:765390858
2293 2293 a, g dbSNP:778936265
2315 2315 a, g dbSNP:144717954
2323 2323 c, t dbSNP:749070899
2339 2339 a, g dbSNP:768613265
2352 2352 c, t dbSNP:775403638
2362 2362 c, g dbSNP:376448550
2370 2370 a, c dbSNP:746821947
2374 2374 c, g dbSNP:770019329
2398 2398 c, t dbSNP:147887754
2401 2401 g, t dbSNP:773331333
2406 2406 a, c, g dbSNP:371970354
2408 2408 a, c, t dbSNP:774477633
2418 2418 a, g dbSNP:540039788
2438 2438 a, g dbSNP:566257885
2439 2439 a, g dbSNP:774113930
2455 2455 c, t dbSNP:202184524
2458 2458 a, g dbSNP:763751776
2471 2471 c, t dbSNP:753445972
2482 2482 a, g dbSNP:558040780
2486 2486 a, g dbSNP:778554042
2498 2498 a, g dbSNP:745419923
2500 2500 a, g dbSNP:758380381
2501 2501 c, t dbSNP:780172945
2503 2503 a, g dbSNP:746772109
2504 2504 a, c dbSNP:552164143
2511 2511 a, c dbSNP:773421444
2519 2519 c, t dbSNP:749471739
2521 2521 a, g dbSNP:767809
2522 2522 a, g dbSNP:774388320
2526 2526 c, t dbSNP:759650076
2528 2528 a, g dbSNP:150069336
2529 2529 c, t dbSNP:775881749
2534 2534 a, g dbSNP:761040547
2536 2536 a, g dbSNP:764369922
2540 2540 a, c, g dbSNP:754294941
2547 2547 c, t dbSNP:765022798
2551 2551 a, g dbSNP:538142998
2560 2560 a, c, t dbSNP:183739128
2561 2561 a, g dbSNP:751458490
2565 2565 c, g dbSNP:568363284
2571 2571 c, t dbSNP:762488785
2575 2575 a, g dbSNP:765806176
2577 2577 a, g dbSNP:373010557
2578 2578 c, g dbSNP:754845064
2587 2587 a, g dbSNP:781226887
2593 2593 a, g dbSNP:752445640
2597 2597 c, t dbSNP:755922886
2600 2600 c, t dbSNP:779047174
2601 2601 a, g dbSNP:759202535
2605 2605 c, g dbSNP:140381835
2634 2634 c, g dbSNP:779983509
2648 2648 a, g dbSNP:747152761
2650 2650 a, g dbSNP:769004916
2653 2653 g, t dbSNP:777218777
2654 2654 c, g dbSNP:150385900
2661 2661 c, t dbSNP:764302249
2664 2664 c, t dbSNP:145393322
2672 2672 c, t dbSNP:372711612
2690 2690 c, g dbSNP:766109034
2693 2693 a, c, t dbSNP:551463686
2709 2709 c, t dbSNP:767056229
2712 2712 c, t dbSNP:765475780
2728 2728 a, g dbSNP:760592370
2734 2734 a, c dbSNP:764067327
2748 2748 c, t dbSNP:753591066
2752 2752 a, t dbSNP:757098704
2758 2758 g, t dbSNP:766455990
2763 2763 c, t dbSNP:570362710
2782 2782 a, c dbSNP:752902180
2785 2785 a, g dbSNP:371187988
2788 2788 c, t dbSNP:149196315
2803 2803 c, g, t dbSNP:748291846
2805 2805 c, g dbSNP:727503740
2815 2815 a, t dbSNP:778451778
2817 2817 a, c dbSNP:749563819
2830 2830 g, t dbSNP:771337725
2841 2841 c, g dbSNP:779345627
2848 2848 c, t dbSNP:778360845
2852 2852 g, t dbSNP:745528944
2861 2861 c, g dbSNP:375595550
2875 2875 c, t dbSNP:774958206
2898 2898 c, t dbSNP:150595117
2904 2904 a, g dbSNP:759883391
2908 2908 c, t dbSNP:767772108
2936 2936 c, t dbSNP:753166628
2943 2943 g, t dbSNP:760225820
2955 2955 g, t dbSNP:763848963
2962 2962 c, t dbSNP:537877002
2967 2967 -, ggcac dbSNP:748708754
2980 2980 c, g, t dbSNP:756849548
2995 2995 c, t dbSNP:138619320
2996 2996 a, g dbSNP:758417927
3019 3019 g, t dbSNP:779689114
3020 3020 c, t dbSNP:746857871
3021 3021 a, g dbSNP:397517238
3031 3031 a, g dbSNP:373584575
3034 3034 a, g dbSNP:543501836
3043 3043 c, g dbSNP:749303911
3044 3044 c, t dbSNP:727503741
3089 3089 a, g dbSNP:182756080
3090 3090 a, g dbSNP:777193704
3092 3092 c, t dbSNP:727505159
3109 3109 c, t dbSNP:149602433
3115 3115 a, g dbSNP:761534024
3118 3118 c, t dbSNP:765020779
3145 3145 c, t dbSNP:201015523
3151 3151 a, g dbSNP:772554405
3155 3155 c, t dbSNP:397517241
3156 3156 a, g dbSNP:766167366
3165 3165 c, t dbSNP:727503742
3166 3166 c, t dbSNP:201526599
3173 3173 -, gag dbSNP:774357613
3193 3193 a, g dbSNP:755500343
3196 3196 c, g dbSNP:149300310
3208 3208 c, t dbSNP:748463679
3234 3234 c, t dbSNP:770283441
3248 3248 c, t dbSNP:778062413
3256 3256 c, t dbSNP:397517242
3262 3262 c, t dbSNP:147415627
3269 3269 a, g dbSNP:773883360
3277 3277 a, t dbSNP:759081621
3292 3292 a, c dbSNP:771949807
3302 3302 c, t dbSNP:373317423
3304 3304 a, c dbSNP:12573090
3322 3322 c, t dbSNP:760396103
3346 3346 a, t dbSNP:763946964
3351 3351 a, g dbSNP:753624420
3359 3359 c, g dbSNP:763202783
3381 3381 c, g dbSNP:766538575
3388 3388 g, t dbSNP:751639273
3392 3392 c, t dbSNP:755118759
3398 3398 c, t dbSNP:781735621
3441 3441 a, t dbSNP:76086805
3453 3453 c, t dbSNP:181553856
3456 3456 a, g dbSNP:751644253
3466 3466 c, g dbSNP:561614915
3477 3477 -, a dbSNP:756151016
3482 3482 a, g dbSNP:528724911
3546 3546 a, c dbSNP:757322860
3556 3556 a, g dbSNP:187329763
3583 3583 c, t dbSNP:143302346
3626 3626 c, g dbSNP:77295081
3630 3630 c, t dbSNP:781526146
3633 3633 a, c dbSNP:79597107
3647 3647 a, c dbSNP:568476628
3653 3653 g, t dbSNP:535835231
3687 3687 -, ct dbSNP:144115212
3718 3718 c, t dbSNP:548234725
3722 3722 a, c dbSNP:1804892
3867 3867 g, t dbSNP:566737975
3877 3877 a, g dbSNP:755916187
3892 3892 a, g dbSNP:192181239
3910 3910 a, g dbSNP:558682607
3935 3935 c, t dbSNP:578158126
3940 3940 c, t dbSNP:368948216
3980 3980 c, g dbSNP:41280414
3986 3986 c, t dbSNP:79816413
4032 4032 a, c dbSNP:182637339
4062 4062 a, c dbSNP:187721829
4070 4070 a, g dbSNP:774201697
4091 4091 c, t dbSNP:561449879
4136 4136 c, t dbSNP:573450784
4163 4163 -, g dbSNP:71021590
4198 4198 c, t dbSNP:536381894
4260 4260 a, g dbSNP:778644714
4321 4321 c, t dbSNP:145634601
4322 4322 -, ta dbSNP:16408
4322 4322 a, c dbSNP:78391049
4323 4323 -, at dbSNP:10691440
4324 4324 -, at dbSNP:377692178
4325 4325 -, at dbSNP:397804906
4326 4326 a, c dbSNP:199954386
4328 4328 c, t dbSNP:200520943
4334 4334 c, t dbSNP:540494357
4351 4351 a, g dbSNP:771598058
4371 4371 a, t dbSNP:1049456
4375 4375 -, c dbSNP:36124091
4425 4425 c, t dbSNP:572703269
4450 4450 -, t dbSNP:751412447
4457 4457 -, ag dbSNP:780897563
4516 4516 g, t dbSNP:565092802
4537 4537 a, c dbSNP:149551128
4541 4541 c, t dbSNP:765518427
4564 4564 a, g dbSNP:550301214
4571 4571 c, t dbSNP:562241495
4616 4616 c, t dbSNP:529687198
4632 4632 c, g dbSNP:763283437
4661 4661 -, tatt dbSNP:149589487
4677 4677 -, agta dbSNP:112557979
4677 4677 c, t dbSNP:71535723
4741 4741 a, g dbSNP:566667255
4775 4775 -, aag dbSNP:779904140
4858 4858 a, g dbSNP:764632864
4860 4860 a, g dbSNP:752039786
4863 4863 a, g dbSNP:757363363
4870 4870 c, t dbSNP:534064723
4902 4902 c, t dbSNP:552401207
4913 4913 c, t dbSNP:747049435
4918 4918 a, t dbSNP:703258
4970 4970 c, t dbSNP:144240368
4993 4993 c, t dbSNP:1804893
5037 5037 -, aaaga dbSNP:140046305
5041 5041 c, g dbSNP:756405514
5044 5044 -, agaaa dbSNP:377566645
5051 5051 g, t dbSNP:780201805
5065 5065 a, g dbSNP:1801382
5070 5070 g, t dbSNP:749090680
5085 5085 c, t dbSNP:372750308
5127 5127 c, t dbSNP:575785254
5128 5128 a, g dbSNP:577038840
5146 5146 -, atc dbSNP:151279619
5150 5150 -, tca dbSNP:35726593
5157 5157 a, g dbSNP:8255
5176 5176 -, aa, aaa dbSNP:370456912
5177 5177 -, aa dbSNP:386371830
5181 5181 a, c dbSNP:1049613
5183 5183 -, c dbSNP:200756813
5183 5183 a, c dbSNP:3829205
5184 5184 a, c dbSNP:3189804
5187 5187 a, c dbSNP:554923257
5188 5188 -, c dbSNP:201189785
5188 5188 a, c dbSNP:3829204
5196 5196 -, aa dbSNP:3037361
5196 5196 -, a dbSNP:59061551
5222 5222 a, c dbSNP:1049614
5225 5225 a, g dbSNP:529702817
5255 5255 c, t dbSNP:540882056
5282 5282 g, t dbSNP:559715454
5283 5283 c, g dbSNP:541995253

Target ORF information:

RefSeq Version XM_005270143
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens vinculin (VCL), transcript variant X2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_005270143

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
3061
3121
3181
ATGCCAGTGT TTCATACGCG CACGATCGAG AGCATCCTGG AGCCGGTGGC ACAGCAGATC 
TCCCACCTGG TGATAATGCA CGAGGAGGGC GAGGTGGACG GCAAAGCCAT TCCTGACCTC
ACCGCGCCCG TGGCCGCCGT GCAGGCGGCC GTCAGCAACC TCGTCCGGGT TGGAAAAGAG
ACTGTTCAAA CCACTGAGGA TCAGATTTTG AAGAGAGATA TGCCACCAGC ATTTATTAAG
GTTGAGAATG CTTGCACCAA GCTTGTCCAG GCAGCTCAGA TGCTTCAGTC AGACCCTTAC
TCAGTGCCTG CTCGAGATTA TCTAATTGAT GGGTCAAGGG GCATCCTCTC TGGAACATCA
GACCTGCTCC TTACCTTCGA TGAGGCTGAG GTCCGTAAAA TTATTAGAGT TTGCAAAGGA
ATTTTGGAAT ATCTTACAGT GGCAGAGGTG GTGGAGACTA TGGAAGATTT GGTCACTTAC
ACAAAGAATC TTGGGCCAGG AATGACTAAG ATGGCCAAGA TGATTGACGA GAGACAGCAG
GAGCTCACTC ACCAGGAGCA CCGAGTGATG TTGGTGAACT CGATGAACAC CGTGAAAGAG
TTGCTGCCAG TTCTCATTTC AGCTATGAAG ATTTTTGTAA CAACTAAAAA CTCAAAAAAC
CAAGGCATAG AGGAAGCTTT AAAAAATCGC AATTTTACTG TAGAAAAAAT GAGTGCTGAA
ATTAATGAGA TAATTCGTGT GTTACAACTC ACCTCTTGGG ATGAAGATGC CTGGGCCAGC
AAGAAGGACA CTGAAGCCAT GAAGAGAGCA TTGGCCTCCA TAGACTCCAA ACTGAACCAG
GCCAAAGGTT GGCTCCGTGA CCCTAGTGCC TCCCCAGGGG ATGCTGGTGA GCAGGCCATC
AGACAGATCT TAGATGAAGC TGGAAAAGTT GGTGAACTCT GTGCAGGCAA AGAACGCAGG
GAGATTCTGG GAACTTGCAA AATGCTAGGG CAGATGACTG ATCAAGTGGC TGACCTCCGT
GCCAGAGGAC AAGGATCCTC ACCGGTGGCC ATGCAGAAAG CTCAGCAGGT ATCTCAGGGT
CTGGATGTGC TCACAGCAAA AGTGGAAAAT GCAGCTCGCA AGCTGGAAGC CATGACCAAC
TCAAAGCAGA GCATTGCAAA GAAGATCGAT GCTGCTCAGA ACTGGCTTGC AGATCCAAAT
GGTGGACCGG AAGGAGAAGA GCAGATTCGA GGTGCTTTGG CTGAAGCTCG GAAAATAGCA
GAATTATGTG ATGATCCTAA AGAAAGAGAT GACATTCTAC GTTCCCTTGG GGAAATATCT
GCTCTGACTT CTAAATTAGC AGATCTACGA AGACAGGGGA AAGGAGATTC TCCAGAGGCT
CGAGCCTTGG CCAAACAGGT GGCCACGGCC CTGCAGAACC TGCAGACCAA AACCAACCGG
GCTGTGGCCA ACAGCAGACC GGCCAAAGCA GCTGTACACC TTGAGGGCAA GATTGAGCAA
GCACAGCGGT GGATTGATAA TCCCACAGTG GATGACCGTG GAGTCGGTCA GGCTGCCATC
CGGGGGCTTG TGGCCGAAGG GCATCGTCTG GCTAATGTTA TGATGGGGCC TTATCGGCAA
GATCTTCTCG CCAAGTGTGA CCGAGTGGAC CAGCTGACAG CCCAGCTGGC TGACCTGGCT
GCCAGAGGGG AAGGGGAGAG TCCTCAGGCA CGAGCACTTG CATCTCAGCT CCAAGACTCC
TTAAAGGATC TAAAAGCTCG GATGCAGGAG GCCATGACTC AGGAAGTGTC AGATGTTTTC
AGCGATACCA CAACTCCCAT CAAGCTGTTG GCAGTGGCAG CCACGGCGCC TCCTGATGCG
CCTAACAGGG AAGAGGTATT TGATGAGAGG GCAGCTAACT TTGAAAACCA TTCAGGAAAG
CTTGGTGCTA CGGCCGAGAA GGCGGCTGCG GTTGGTACTG CTAATAAATC AACAGTGGAA
GGCATTCAGG CCTCAGTGAA GACGGCCCGA GAACTCACAC CCCAGGTGGT CTCGGCTGCT
CGTATCTTAC TTAGGAACCC TGGAAATCAA GCTGCTTATG AACATTTTGA GACCATGAAG
AACCAGTGGA TCGATAATGT TGAAAAAATG ACAGGGCTGG TGGACGAAGC CATTGATACC
AAATCTCTGT TGGATGCTTC AGAAGAAGCA ATTAAAAAAG ACCTGGACAA GTGCAAGGTA
GCTATGGCCA ACATTCAGCC TCAGATGCTG GTTGCTGGGG CAACCAGTAT TGCTCGTCGG
GCCAACCGGA TCCTGCTGGT GGCTAAGAGG GAGGTGGAGA ATTCCGAGGA TCCCAAGTTC
CGTGAGGCTG TGAAAGCTGC CTCTGATGAA TTGAGCAAAA CCATCTCCCC GATGGTGATG
GATGCAAAAG CTGTGGCTGG AAACATTTCC GACCCTGGAC TGCAAAAGAG CTTCCTGGAC
TCAGGATATC GGATCCTGGG AGCTGTGGCC AAGGTCAGAG AAGCCTTCCA ACCTCAGGAG
CCTGACTTCC CGCCGCCTCC ACCAGACCTT GAACAACTCC GACTAACAGA TGAGCTTGCT
CCTCCCAAAC CACCTCTGCC TGAAGGTGAG GTCCCTCCAC CTAGGCCTCC ACCACCAGAG
GAAAAGGATG AAGAGTTCCC TGAGCAGAAG GCCGGGGAGG TGATTAACCA GCCAATGATG
ATGGCTGCCA GACAGCTCCA TGATGAAGCT CGCAAATGGT CCAGCAAGGG CAATGACATC
ATTGCAGCAG CCAAGCGCAT GGCTCTGCTG ATGGCTGAGA TGTCTCGGCT GGTAAGAGGG
GGCAGTGGTA CCAAGCGGGC ACTCATTCAG TGTGCCAAGG ACATCGCCAA GGCCTCAGAT
GAGGTGACTC GGTTGGCCAA GGAGGTTGCC AAGCAGTGCA CAGATAAACG GATTAGAACC
AACCTCTTAC AGGTATGTGA GCGAATCCCA ACCATAAGCA CCCAGCTCAA AATCCTGTCC
ACAGTGAAGG CCACCATGCT GGGCCGGACC AACATCAGTG ATGAGGAGTC TGAGCAGGCC
ACAGAGATGC TGGTTCACAA TGCCCAGAAC CTCATGCAGT CTGTGAAGGA GACTGTGCGG
GAAGCTGAAG CTGCTTCAAT CAAAATTCGA ACAGATGCTG GATTTACACT GCGCTGGGTT
AGAAAGACTC CCTGGTACCA GTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu25616
Accession Version NM_014000.2
Sequence Information ORF Nucleotide Sequence (Length: 3405bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product vinculin isoform meta-VCL
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL708715.1, BC039174.1, AK126978.1, AL832130.1, AA368699.1, AL700886.1, BC013847.1 and AI290052.1. This sequence is a reference standard in the RefSeqGene project. On Jul 26, 2004 this sequence version replaced gi:7669549. Summary: Vinculin is a cytoskeletal protein associated with cell-cell and cell-matrix junctions, where it is thought to function as one of several interacting proteins involved in anchoring F-actin to the membrane. Defects in VCL are the cause of cardiomyopathy dilated type 1W. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq, Jul 2008]. Transcript Variant: This variant (1) differs from variant 2 in having an additional exon in the 3' coding region. It thus encodes a longer isoform (meta-VCL). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
3061
3121
3181
3241
3301
3361
ATGCCAGTGT TTCATACGCG CACGATCGAG AGCATCCTGG AGCCGGTGGC ACAGCAGATC 
TCCCACCTGG TGATAATGCA CGAGGAGGGC GAGGTGGACG GCAAAGCCAT TCCTGACCTC
ACCGCGCCCG TGGCCGCCGT GCAGGCGGCC GTCAGCAACC TCGTCCGGGT TGGAAAAGAG
ACTGTTCAAA CCACTGAGGA TCAGATTTTG AAGAGAGATA TGCCACCAGC ATTTATTAAG
GTTGAGAATG CTTGCACCAA GCTTGTCCAG GCAGCTCAGA TGCTTCAGTC AGACCCTTAC
TCAGTGCCTG CTCGAGATTA TCTAATTGAT GGGTCAAGGG GCATCCTCTC TGGAACATCA
GACCTGCTCC TTACCTTCGA TGAGGCTGAG GTCCGTAAAA TTATTAGAGT TTGCAAAGGA
ATTTTGGAAT ATCTTACAGT GGCAGAGGTG GTGGAGACTA TGGAAGATTT GGTCACTTAC
ACAAAGAATC TTGGGCCAGG AATGACTAAG ATGGCCAAGA TGATTGACGA GAGACAGCAG
GAGCTCACTC ACCAGGAGCA CCGAGTGATG TTGGTGAACT CGATGAACAC CGTGAAAGAG
TTGCTGCCAG TTCTCATTTC AGCTATGAAG ATTTTTGTAA CAACTAAAAA CTCAAAAAAC
CAAGGCATAG AGGAAGCTTT AAAAAATCGC AATTTTACTG TAGAAAAAAT GAGTGCTGAA
ATTAATGAGA TAATTCGTGT GTTACAACTC ACCTCTTGGG ATGAAGATGC CTGGGCCAGC
AAGGACACTG AAGCCATGAA GAGAGCATTG GCCTCCATAG ACTCCAAACT GAACCAGGCC
AAAGGTTGGC TCCGTGACCC TAGTGCCTCC CCAGGGGATG CTGGTGAGCA GGCCATCAGA
CAGATCTTAG ATGAAGCTGG AAAAGTTGGT GAACTCTGTG CAGGCAAAGA ACGCAGGGAG
ATTCTGGGAA CTTGCAAAAT GCTAGGGCAG ATGACTGATC AAGTGGCTGA CCTCCGTGCC
AGAGGACAAG GATCCTCACC GGTGGCCATG CAGAAAGCTC AGCAGGTATC TCAGGGTCTG
GATGTGCTCA CAGCAAAAGT GGAAAATGCA GCTCGCAAGC TGGAAGCCAT GACCAACTCA
AAGCAGAGCA TTGCAAAGAA GATCGATGCT GCTCAGAACT GGCTTGCAGA TCCAAATGGT
GGACCGGAAG GAGAAGAGCA GATTCGAGGT GCTTTGGCTG AAGCTCGGAA AATAGCAGAA
TTATGTGATG ATCCTAAAGA AAGAGATGAC ATTCTACGTT CCCTTGGGGA AATATCTGCT
CTGACTTCTA AATTAGCAGA TCTACGAAGA CAGGGGAAAG GAGATTCTCC AGAGGCTCGA
GCCTTGGCCA AACAGGTGGC CACGGCCCTG CAGAACCTGC AGACCAAAAC CAACCGGGCT
GTGGCCAACA GCAGACCGGC CAAAGCAGCT GTACACCTTG AGGGCAAGAT TGAGCAAGCA
CAGCGGTGGA TTGATAATCC CACAGTGGAT GACCGTGGAG TCGGTCAGGC TGCCATCCGG
GGGCTTGTGG CCGAAGGGCA TCGTCTGGCT AATGTTATGA TGGGGCCTTA TCGGCAAGAT
CTTCTCGCCA AGTGTGACCG AGTGGACCAG CTGACAGCCC AGCTGGCTGA CCTGGCTGCC
AGAGGGGAAG GGGAGAGTCC TCAGGCACGA GCACTTGCAT CTCAGCTCCA AGACTCCTTA
AAGGATCTAA AAGCTCGGAT GCAGGAGGCC ATGACTCAGG AAGTGTCAGA TGTTTTCAGC
GATACCACAA CTCCCATCAA GCTGTTGGCA GTGGCAGCCA CGGCGCCTCC TGATGCGCCT
AACAGGGAAG AGGTATTTGA TGAGAGGGCA GCTAACTTTG AAAACCATTC AGGAAAGCTT
GGTGCTACGG CCGAGAAGGC GGCTGCGGTT GGTACTGCTA ATAAATCAAC AGTGGAAGGC
ATTCAGGCCT CAGTGAAGAC GGCCCGAGAA CTCACACCCC AGGTGGTCTC GGCTGCTCGT
ATCTTACTTA GGAACCCTGG AAATCAAGCT GCTTATGAAC ATTTTGAGAC CATGAAGAAC
CAGTGGATCG ATAATGTTGA AAAAATGACA GGGCTGGTGG ACGAAGCCAT TGATACCAAA
TCTCTGTTGG ATGCTTCAGA AGAAGCAATT AAAAAAGACC TGGACAAGTG CAAGGTAGCT
ATGGCCAACA TTCAGCCTCA GATGCTGGTT GCTGGGGCAA CCAGTATTGC TCGTCGGGCC
AACCGGATCC TGCTGGTGGC TAAGAGGGAG GTGGAGAATT CCGAGGATCC CAAGTTCCGT
GAGGCTGTGA AAGCTGCCTC TGATGAATTG AGCAAAACCA TCTCCCCGAT GGTGATGGAT
GCAAAAGCTG TGGCTGGAAA CATTTCCGAC CCTGGACTGC AAAAGAGCTT CCTGGACTCA
GGATATCGGA TCCTGGGAGC TGTGGCCAAG GTCAGAGAAG CCTTCCAACC TCAGGAGCCT
GACTTCCCGC CGCCTCCACC AGACCTTGAA CAACTCCGAC TAACAGATGA GCTTGCTCCT
CCCAAACCAC CTCTGCCTGA AGGTGAGGTC CCTCCACCTA GGCCTCCACC ACCAGAGGAA
AAGGATGAAG AGTTCCCTGA GCAGAAGGCC GGGGAGGTGA TTAACCAGCC AATGATGATG
GCTGCCAGAC AGCTCCATGA TGAAGCTCGC AAATGGTCCA GCAAGCCGGG CATCCCAGCC
GCTGAGGTGG GTATAGGTGT TGTAGCTGAG GCAGATGCGG CCGATGCTGC TGGCTTCCCT
GTCCCCCCTG ACATGGAAGA CGATTACGAA CCTGAGCTGC TGTTAATGCC ATCCAATCAG
CCGGTCAACC AGCCCATTCT GGCCGCGGCT CAGTCCTTGC ATCGGGAAGC TACCAAGTGG
TCTAGTAAGG GCAATGACAT CATTGCAGCA GCCAAGCGCA TGGCTCTGCT GATGGCTGAG
ATGTCTCGGC TGGTAAGAGG GGGCAGTGGT ACCAAGCGGG CACTCATTCA GTGTGCCAAG
GACATCGCCA AGGCCTCAGA TGAGGTGACT CGGTTGGCCA AGGAGGTTGC CAAGCAGTGC
ACAGATAAAC GGATTAGAAC CAACCTCTTA CAGGTATGTG AGCGAATCCC AACCATAAGC
ACCCAGCTCA AAATCCTGTC CACAGTGAAG GCCACCATGC TGGGCCGGAC CAACATCAGT
GATGAGGAGT CTGAGCAGGC CACAGAGATG CTGGTTCACA ATGCCCAGAA CCTCATGCAG
TCTGTGAAGG AGACTGTGCG GGAAGCTGAA GCTGCTTCAA TCAAAATTCG AACAGATGCT
GGATTTACAC TGCGCTGGGT TAGAAAGACT CCCTGGTACC AGTAG
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_054706.1
CDS95..3499
Misc Feature(1)2..4(+)
Misc Feature(2)98..2599(+)
Misc Feature(3)101..3496(+)
Misc Feature(4)347..349(+)
Misc Feature(5)392..394(+)
Misc Feature(6)596..718(+)
Misc Feature(7)611..613(+)
Misc Feature(8)869..1861(+)
Misc Feature(9)956..958(+)
Misc Feature(10)956..958(+)
Misc Feature(11)962..964(+)
Misc Feature(12)962..964(+)
Misc Feature(13)1130..1132(+)
Misc Feature(14)1394..1396(+)
Misc Feature(15)1580..1582(+)
Misc Feature(16)1904..1906(+)
Misc Feature(17)2168..2170(+)
Misc Feature(18)2255..2257(+)
Misc Feature(19)2255..2257(+)
Misc Feature(20)2558..2560(+)
Misc Feature(21)2558..2560(+)
Misc Feature(22)2600..2728(+)
Misc Feature(23)2729..3496(+)
Misc Feature(24)3101..3232(+)
Misc Feature(25)3395..3397(+)
Misc Feature(26)3431..3433(+)
Misc Feature(27)3452..3496(+)
Misc Feature(28)3491..3493(+)
Misc Feature(29)3491..3493(+)
Exon (1)1..262
Gene:VCL
Gene Synonym:
Exon (2)263..333
Gene:VCL
Gene Synonym:
Exon (3)334..484
Gene:VCL
Gene Synonym:
Exon (4)485..593
Gene:VCL
Gene Synonym:
Exon (5)594..716
Gene:VCL
Gene Synonym:
Exon (6)717..877
Gene:VCL
Gene Synonym:
Exon (7)878..968
Gene:VCL
Gene Synonym:
Exon (8)969..1116
Gene:VCL
Gene Synonym:
Exon (9)1117..1270
Gene:VCL
Gene Synonym:
Exon (10)1271..1446
Gene:VCL
Gene Synonym:
Exon (11)1447..1637
Gene:VCL
Gene Synonym:
Exon (12)1638..1837
Gene:VCL
Gene Synonym:
Exon (13)1838..1966
Gene:VCL
Gene Synonym:
Exon (14)1967..2116
Gene:VCL
Gene Synonym:
Exon (15)2117..2225
Gene:VCL
Gene Synonym:
Exon (16)2226..2528
Gene:VCL
Gene Synonym:
Exon (17)2529..2653
Gene:VCL
Gene Synonym:
Exon (18)2654..2839
Gene:VCL
Gene Synonym:
Exon (19)2840..3043
Gene:VCL
Gene Synonym:
Exon (20)3044..3247
Gene:VCL
Gene Synonym:
Exon (21)3248..3352
Gene:VCL
Gene Synonym:
Exon (22)3353..5490
Gene:VCL
Gene Synonym:
Translation
Position Chain Variation Link
6 6 a, c dbSNP:763933845
29 29 c, g dbSNP:533231503
31 31 g, t dbSNP:551418878
35 35 c, t dbSNP:370879754
45 45 a, g dbSNP:536893103
58 58 c, t dbSNP:761931436
62 62 c, g dbSNP:368934359
67 67 a, g dbSNP:765704599
69 69 a, g, t dbSNP:750972760
82 82 a, g dbSNP:780482320
86 86 c, g dbSNP:548768602
90 90 c, t dbSNP:754654170
100 100 a, c, g dbSNP:753870747
114 114 g, t dbSNP:764871020
124 124 a, g dbSNP:146750460
125 125 a, g dbSNP:397517240
126 126 a, g dbSNP:777811020
127 127 c, t dbSNP:749266193
128 128 a, g dbSNP:770570643
130 130 c, t dbSNP:774195260
133 133 g, t dbSNP:759312175
139 139 a, g dbSNP:775062250
161 161 a, c dbSNP:776882033
175 175 -, g dbSNP:750937217
175 175 c, t dbSNP:200733607
193 193 c, t dbSNP:568175141
197 197 a, g dbSNP:139329923
208 208 a, t dbSNP:750838330
214 214 c, t dbSNP:144080529
224 224 a, g dbSNP:554116863
252 252 a, g dbSNP:751938777
257 257 g, t dbSNP:755441334
277 277 g, t dbSNP:776787274
278 278 a, g dbSNP:147809878
279 279 c, t dbSNP:769799445
280 280 c, t dbSNP:773335930
283 283 a, g dbSNP:571901910
291 291 a, g dbSNP:762999933
313 313 a, t dbSNP:766886119
318 318 c, t dbSNP:373830664
319 319 a, g dbSNP:759937112
332 332 a, c dbSNP:775532257
349 349 c, t dbSNP:117384664
366 366 a, c dbSNP:749355014
371 371 c, t dbSNP:770946581
376 376 a, g dbSNP:774870551
394 394 c, t dbSNP:71535779
407 407 c, t dbSNP:397517239
433 433 a, g dbSNP:56314318
436 436 c, g dbSNP:775990121
457 457 c, t dbSNP:761174435
460 460 a, g dbSNP:199562976
472 472 c, t dbSNP:148966602
478 478 a, g dbSNP:756746383
490 490 c, t dbSNP:761378361
498 498 c, t dbSNP:373744314
506 506 g, t dbSNP:749922427
518 518 c, t dbSNP:762497815
547 547 c, g dbSNP:766271456
549 549 a, g dbSNP:751528827
551 551 a, c dbSNP:376921881
566 566 g, t dbSNP:371583362
576 576 c, t dbSNP:376226543
577 577 a, g dbSNP:754020959
586 586 g, t dbSNP:143702799
592 592 a, g dbSNP:779332764
598 598 a, g dbSNP:779240568
602 602 a, g dbSNP:750701726
605 605 a, g dbSNP:758498714
621 621 a, g dbSNP:573623641
622 622 c, t dbSNP:746453891
634 634 a, g dbSNP:769031743
642 642 c, t dbSNP:781748134
649 649 a, g dbSNP:748428678
656 656 c, t dbSNP:397517244
657 657 a, g dbSNP:770173689
659 659 a, c, g, t dbSNP:151045204
665 665 c, t dbSNP:370334093
676 676 a, g dbSNP:773725513
679 679 a, g dbSNP:759141517
684 684 c, t dbSNP:189242810
685 685 c, t dbSNP:199960157
686 686 a, g, t dbSNP:760340545
689 689 -, a dbSNP:777492997
704 704 c, g dbSNP:727504585
715 715 a, t dbSNP:750610030
719 719 a, g, t dbSNP:144683137
720 720 a, t dbSNP:751243981
729 729 c, t dbSNP:754962481
730 730 c, t dbSNP:767648679
735 735 c, t dbSNP:753078158
743 743 a, g dbSNP:727505216
747 747 -, a dbSNP:770713697
753 753 -, a dbSNP:397517245
754 754 c, t dbSNP:56264452
770 770 a, g dbSNP:146910007
774 774 -, a dbSNP:776583302
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1600 1600 a, g dbSNP:2228373
1605 1605 c, t dbSNP:745343813
1621 1621 a, g dbSNP:564882287
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1629 1629 a, g, t dbSNP:367568441
1636 1636 c, t dbSNP:7904077
1649 1649 a, c dbSNP:141033098
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1812 1812 c, g dbSNP:777130723
1815 1815 c, t dbSNP:574643494
1850 1850 c, t dbSNP:770778046
1851 1851 a, g dbSNP:774076269
1852 1852 a, c, g dbSNP:759103182
1856 1856 c, t dbSNP:727504381
1859 1859 a, g dbSNP:187247459
1882 1882 a, c dbSNP:199582103
1886 1886 a, g dbSNP:397517235
1887 1887 c, t dbSNP:763977443
1892 1892 a, c dbSNP:397517236
1901 1901 a, c, g, t dbSNP:753788366
1904 1904 a, g dbSNP:754470470
1910 1910 a, g dbSNP:750293810
1924 1924 a, c dbSNP:755136660
1932 1932 c, g dbSNP:781520177
1934 1934 a, t dbSNP:142695754
1935 1935 c, t dbSNP:748140302
1936 1936 a, g dbSNP:144117013
1938 1938 c, t dbSNP:148669762
1939 1939 a, g dbSNP:749812890
1950 1950 c, t dbSNP:771628544
1955 1955 a, g dbSNP:374309823
1957 1957 c, g dbSNP:746293391
1959 1959 a, g dbSNP:771590749
1960 1960 a, g dbSNP:372402817
1965 1965 a, t dbSNP:775238596
1979 1979 a, g dbSNP:748683598
1982 1982 a, g dbSNP:727503739
1984 1984 a, t dbSNP:774940704
1995 1995 a, c dbSNP:746660046
2001 2001 a, g dbSNP:71579374
2002 2002 c, t dbSNP:372696553
2009 2009 a, c dbSNP:761356586
2015 2015 a, g dbSNP:765123545
2022 2022 c, t dbSNP:150643310
2026 2026 c, t dbSNP:762594014
2027 2027 a, g dbSNP:766197411
2031 2031 a, c dbSNP:751374648
2034 2034 c, t dbSNP:534449109
2041 2041 a, g dbSNP:200168992
2045 2045 a, g dbSNP:753936921
2050 2050 c, t dbSNP:757443298
2063 2063 a, g dbSNP:779238311
2064 2064 c, t dbSNP:750946056
2067 2067 c, t dbSNP:372691803
2087 2087 c, g dbSNP:780455788
2095 2095 a, g dbSNP:747424067
2098 2098 a, c dbSNP:768269673
2099 2099 c, t dbSNP:780856981
2100 2100 a, g, t dbSNP:759771302
2110 2110 a, g dbSNP:773292837
2116 2116 a, g dbSNP:772952515
2119 2119 a, g dbSNP:140766884
2122 2122 c, g, t dbSNP:528539468
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2129 2129 g, t dbSNP:375392559
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2231 2231 a, g dbSNP:374737519
2235 2235 a, g dbSNP:748791215
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2248 2248 -, t dbSNP:765390858
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2300 2300 a, g dbSNP:768613265
2313 2313 c, t dbSNP:775403638
2323 2323 c, g dbSNP:376448550
2331 2331 a, c dbSNP:746821947
2335 2335 c, g dbSNP:770019329
2359 2359 c, t dbSNP:147887754
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2367 2367 a, c, g dbSNP:371970354
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2609 2609 a, g dbSNP:747152761
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2622 2622 c, t dbSNP:764302249
2625 2625 c, t dbSNP:145393322
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2651 2651 c, g dbSNP:766109034
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2673 2673 c, t dbSNP:765475780
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2709 2709 c, t dbSNP:753591066
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2776 2776 a, t dbSNP:778451778
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2802 2802 c, g dbSNP:779345627
2809 2809 c, t dbSNP:778360845
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2894 2894 a, g dbSNP:750750224
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2896 2896 c, t dbSNP:372381809
2897 2897 a, g dbSNP:746658025
2901 2901 c, t dbSNP:754681045
2908 2908 c, g dbSNP:2131956
2917 2917 c, t dbSNP:747647927
2919 2919 a, c dbSNP:375627694
2921 2921 c, g dbSNP:71579375
2922 2922 -, ct dbSNP:781036800
2923 2923 c, t dbSNP:200480221
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2987 2987 c, t dbSNP:749236817
2998 2998 c, t dbSNP:558112511
2999 2999 a, g dbSNP:199751261
3000 3000 a, c, t dbSNP:534101808
3002 3002 c, g dbSNP:776730962
3003 3003 c, g dbSNP:761884758
3008 3008 a, t dbSNP:765226093
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3018 3018 a, g, t dbSNP:767325003
3063 3063 c, t dbSNP:150595117
3069 3069 a, g dbSNP:759883391
3073 3073 c, t dbSNP:767772108
3101 3101 c, t dbSNP:753166628
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3160 3160 c, t dbSNP:138619320
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3184 3184 g, t dbSNP:779689114
3185 3185 c, t dbSNP:746857871
3186 3186 a, g dbSNP:397517238
3196 3196 a, g dbSNP:373584575
3199 3199 a, g dbSNP:543501836
3208 3208 c, g dbSNP:749303911
3209 3209 c, t dbSNP:727503741
3254 3254 a, g dbSNP:182756080
3255 3255 a, g dbSNP:777193704
3257 3257 c, t dbSNP:727505159
3274 3274 c, t dbSNP:149602433
3280 3280 a, g dbSNP:761534024
3283 3283 c, t dbSNP:765020779
3310 3310 c, t dbSNP:201015523
3316 3316 a, g dbSNP:772554405
3320 3320 c, t dbSNP:397517241
3321 3321 a, g dbSNP:766167366
3330 3330 c, t dbSNP:727503742
3331 3331 c, t dbSNP:201526599
3338 3338 -, gag dbSNP:774357613
3358 3358 a, g dbSNP:755500343
3361 3361 c, g dbSNP:149300310
3373 3373 c, t dbSNP:748463679
3399 3399 c, t dbSNP:770283441
3413 3413 c, t dbSNP:778062413
3421 3421 c, t dbSNP:397517242
3427 3427 c, t dbSNP:147415627
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3442 3442 a, t dbSNP:759081621
3457 3457 a, c dbSNP:771949807
3467 3467 c, t dbSNP:373317423
3469 3469 a, c dbSNP:12573090
3487 3487 c, t dbSNP:760396103
3511 3511 a, t dbSNP:763946964
3516 3516 a, g dbSNP:753624420
3524 3524 c, g dbSNP:763202783
3546 3546 c, g dbSNP:766538575
3553 3553 g, t dbSNP:751639273
3557 3557 c, t dbSNP:755118759
3563 3563 c, t dbSNP:781735621
3606 3606 a, t dbSNP:76086805
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3621 3621 a, g dbSNP:751644253
3631 3631 c, g dbSNP:561614915
3642 3642 -, a dbSNP:756151016
3647 3647 a, g dbSNP:528724911
3711 3711 a, c dbSNP:757322860
3721 3721 a, g dbSNP:187329763
3748 3748 c, t dbSNP:143302346
3791 3791 c, g dbSNP:77295081
3795 3795 c, t dbSNP:781526146
3798 3798 a, c dbSNP:79597107
3812 3812 a, c dbSNP:568476628
3818 3818 g, t dbSNP:535835231
3852 3852 -, ct dbSNP:144115212
3883 3883 c, t dbSNP:548234725
3887 3887 a, c dbSNP:1804892
4032 4032 g, t dbSNP:566737975
4042 4042 a, g dbSNP:755916187
4057 4057 a, g dbSNP:192181239
4075 4075 a, g dbSNP:558682607
4100 4100 c, t dbSNP:578158126
4105 4105 c, t dbSNP:368948216
4145 4145 c, g dbSNP:41280414
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4197 4197 a, c dbSNP:182637339
4227 4227 a, c dbSNP:187721829
4235 4235 a, g dbSNP:774201697
4256 4256 c, t dbSNP:561449879
4301 4301 c, t dbSNP:573450784
4328 4328 -, g dbSNP:71021590
4363 4363 c, t dbSNP:536381894
4425 4425 a, g dbSNP:778644714
4486 4486 c, t dbSNP:145634601
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4487 4487 a, c dbSNP:78391049
4488 4488 -, at dbSNP:10691440
4489 4489 -, at dbSNP:377692178
4490 4490 -, at dbSNP:397804906
4491 4491 a, c dbSNP:199954386
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4516 4516 a, g dbSNP:771598058
4536 4536 a, t dbSNP:1049456
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4702 4702 a, c dbSNP:149551128
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4729 4729 a, g dbSNP:550301214
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4781 4781 c, t dbSNP:529687198
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5025 5025 a, g dbSNP:752039786
5028 5028 a, g dbSNP:757363363
5035 5035 c, t dbSNP:534064723
5067 5067 c, t dbSNP:552401207
5078 5078 c, t dbSNP:747049435
5083 5083 a, t dbSNP:703258
5135 5135 c, t dbSNP:144240368
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5202 5202 -, aaaga dbSNP:140046305
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5230 5230 a, g dbSNP:1801382
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5311 5311 -, atc dbSNP:151279619
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5387 5387 a, c dbSNP:1049614
5390 5390 a, g dbSNP:529702817
5420 5420 c, t dbSNP:540882056
5447 5447 g, t dbSNP:559715454
5448 5448 c, g dbSNP:541995253

Target ORF information:

RefSeq Version NM_014000
Organism Homo sapiens (human)
Definition Homo sapiens vinculin (VCL), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_014000

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
3061
3121
3181
3241
3301
3361
ATGCCAGTGT TTCATACGCG CACGATCGAG AGCATCCTGG AGCCGGTGGC ACAGCAGATC 
TCCCACCTGG TGATAATGCA CGAGGAGGGC GAGGTGGACG GCAAAGCCAT TCCTGACCTC
ACCGCGCCCG TGGCCGCCGT GCAGGCGGCC GTCAGCAACC TCGTCCGGGT TGGAAAAGAG
ACTGTTCAAA CCACTGAGGA TCAGATTTTG AAGAGAGATA TGCCACCAGC ATTTATTAAG
GTTGAGAATG CTTGCACCAA GCTTGTCCAG GCAGCTCAGA TGCTTCAGTC AGACCCTTAC
TCAGTGCCTG CTCGAGATTA TCTAATTGAT GGGTCAAGGG GCATCCTCTC TGGAACATCA
GACCTGCTCC TTACCTTCGA TGAGGCTGAG GTCCGTAAAA TTATTAGAGT TTGCAAAGGA
ATTTTGGAAT ATCTTACAGT GGCAGAGGTG GTGGAGACTA TGGAAGATTT GGTCACTTAC
ACAAAGAATC TTGGGCCAGG AATGACTAAG ATGGCCAAGA TGATTGACGA GAGACAGCAG
GAGCTCACTC ACCAGGAGCA CCGAGTGATG TTGGTGAACT CGATGAACAC CGTGAAAGAG
TTGCTGCCAG TTCTCATTTC AGCTATGAAG ATTTTTGTAA CAACTAAAAA CTCAAAAAAC
CAAGGCATAG AGGAAGCTTT AAAAAATCGC AATTTTACTG TAGAAAAAAT GAGTGCTGAA
ATTAATGAGA TAATTCGTGT GTTACAACTC ACCTCTTGGG ATGAAGATGC CTGGGCCAGC
AAGGACACTG AAGCCATGAA GAGAGCATTG GCCTCCATAG ACTCCAAACT GAACCAGGCC
AAAGGTTGGC TCCGTGACCC TAGTGCCTCC CCAGGGGATG CTGGTGAGCA GGCCATCAGA
CAGATCTTAG ATGAAGCTGG AAAAGTTGGT GAACTCTGTG CAGGCAAAGA ACGCAGGGAG
ATTCTGGGAA CTTGCAAAAT GCTAGGGCAG ATGACTGATC AAGTGGCTGA CCTCCGTGCC
AGAGGACAAG GATCCTCACC GGTGGCCATG CAGAAAGCTC AGCAGGTATC TCAGGGTCTG
GATGTGCTCA CAGCAAAAGT GGAAAATGCA GCTCGCAAGC TGGAAGCCAT GACCAACTCA
AAGCAGAGCA TTGCAAAGAA GATCGATGCT GCTCAGAACT GGCTTGCAGA TCCAAATGGT
GGACCGGAAG GAGAAGAGCA GATTCGAGGT GCTTTGGCTG AAGCTCGGAA AATAGCAGAA
TTATGTGATG ATCCTAAAGA AAGAGATGAC ATTCTACGTT CCCTTGGGGA AATATCTGCT
CTGACTTCTA AATTAGCAGA TCTACGAAGA CAGGGGAAAG GAGATTCTCC AGAGGCTCGA
GCCTTGGCCA AACAGGTGGC CACGGCCCTG CAGAACCTGC AGACCAAAAC CAACCGGGCT
GTGGCCAACA GCAGACCGGC CAAAGCAGCT GTACACCTTG AGGGCAAGAT TGAGCAAGCA
CAGCGGTGGA TTGATAATCC CACAGTGGAT GACCGTGGAG TCGGTCAGGC TGCCATCCGG
GGGCTTGTGG CCGAAGGGCA TCGTCTGGCT AATGTTATGA TGGGGCCTTA TCGGCAAGAT
CTTCTCGCCA AGTGTGACCG AGTGGACCAG CTGACAGCCC AGCTGGCTGA CCTGGCTGCC
AGAGGGGAAG GGGAGAGTCC TCAGGCACGA GCACTTGCAT CTCAGCTCCA AGACTCCTTA
AAGGATCTAA AAGCTCGGAT GCAGGAGGCC ATGACTCAGG AAGTGTCAGA TGTTTTCAGC
GATACCACAA CTCCCATCAA GCTGTTGGCA GTGGCAGCCA CGGCGCCTCC TGATGCGCCT
AACAGGGAAG AGGTATTTGA TGAGAGGGCA GCTAACTTTG AAAACCATTC AGGAAAGCTT
GGTGCTACGG CCGAGAAGGC GGCTGCGGTT GGTACTGCTA ATAAATCAAC AGTGGAAGGC
ATTCAGGCCT CAGTGAAGAC GGCCCGAGAA CTCACACCCC AGGTGGTCTC GGCTGCTCGT
ATCTTACTTA GGAACCCTGG AAATCAAGCT GCTTATGAAC ATTTTGAGAC CATGAAGAAC
CAGTGGATCG ATAATGTTGA AAAAATGACA GGGCTGGTGG ACGAAGCCAT TGATACCAAA
TCTCTGTTGG ATGCTTCAGA AGAAGCAATT AAAAAAGACC TGGACAAGTG CAAGGTAGCT
ATGGCCAACA TTCAGCCTCA GATGCTGGTT GCTGGGGCAA CCAGTATTGC TCGTCGGGCC
AACCGGATCC TGCTGGTGGC TAAGAGGGAG GTGGAGAATT CCGAGGATCC CAAGTTCCGT
GAGGCTGTGA AAGCTGCCTC TGATGAATTG AGCAAAACCA TCTCCCCGAT GGTGATGGAT
GCAAAAGCTG TGGCTGGAAA CATTTCCGAC CCTGGACTGC AAAAGAGCTT CCTGGACTCA
GGATATCGGA TCCTGGGAGC TGTGGCCAAG GTCAGAGAAG CCTTCCAACC TCAGGAGCCT
GACTTCCCGC CGCCTCCACC AGACCTTGAA CAACTCCGAC TAACAGATGA GCTTGCTCCT
CCCAAACCAC CTCTGCCTGA AGGTGAGGTC CCTCCACCTA GGCCTCCACC ACCAGAGGAA
AAGGATGAAG AGTTCCCTGA GCAGAAGGCC GGGGAGGTGA TTAACCAGCC AATGATGATG
GCTGCCAGAC AGCTCCATGA TGAAGCTCGC AAATGGTCCA GCAAGCCGGG CATCCCAGCC
GCTGAGGTGG GTATAGGTGT TGTAGCTGAG GCAGATGCGG CCGATGCTGC TGGCTTCCCT
GTCCCCCCTG ACATGGAAGA CGATTACGAA CCTGAGCTGC TGTTAATGCC ATCCAATCAG
CCGGTCAACC AGCCCATTCT GGCCGCGGCT CAGTCCTTGC ATCGGGAAGC TACCAAGTGG
TCTAGTAAGG GCAATGACAT CATTGCAGCA GCCAAGCGCA TGGCTCTGCT GATGGCTGAG
ATGTCTCGGC TGGTAAGAGG GGGCAGTGGT ACCAAGCGGG CACTCATTCA GTGTGCCAAG
GACATCGCCA AGGCCTCAGA TGAGGTGACT CGGTTGGCCA AGGAGGTTGC CAAGCAGTGC
ACAGATAAAC GGATTAGAAC CAACCTCTTA CAGGTATGTG AGCGAATCCC AACCATAAGC
ACCCAGCTCA AAATCCTGTC CACAGTGAAG GCCACCATGC TGGGCCGGAC CAACATCAGT
GATGAGGAGT CTGAGCAGGC CACAGAGATG CTGGTTCACA ATGCCCAGAA CCTCATGCAG
TCTGTGAAGG AGACTGTGCG GGAAGCTGAA GCTGCTTCAA TCAAAATTCG AACAGATGCT
GGATTTACAC TGCGCTGGGT TAGAAAGACT CCCTGGTACC AGTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu25331
Accession Version NM_003373.3
Sequence Information ORF Nucleotide Sequence (Length: 3201bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product vinculin isoform VCL
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL708715.1, BC039174.1, BX537994.1, AK126978.1, BC013847.1, AI290052.1 and AL832130.1. On Jul 26, 2004 this sequence version replaced gi:7669551. Summary: Vinculin is a cytoskeletal protein associated with cell-cell and cell-matrix junctions, where it is thought to function as one of several interacting proteins involved in anchoring F-actin to the membrane. Defects in VCL are the cause of cardiomyopathy dilated type 1W. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq, Jul 2008]. Transcript Variant: This variant (2) lacks a 3' coding exon, as compared to variant 1. It encodes a shorter isoform (VCL), which is the major talin-binding protein in platelets. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC039174.1, M33308.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
3061
3121
3181
ATGCCAGTGT TTCATACGCG CACGATCGAG AGCATCCTGG AGCCGGTGGC ACAGCAGATC 
TCCCACCTGG TGATAATGCA CGAGGAGGGC GAGGTGGACG GCAAAGCCAT TCCTGACCTC
ACCGCGCCCG TGGCCGCCGT GCAGGCGGCC GTCAGCAACC TCGTCCGGGT TGGAAAAGAG
ACTGTTCAAA CCACTGAGGA TCAGATTTTG AAGAGAGATA TGCCACCAGC ATTTATTAAG
GTTGAGAATG CTTGCACCAA GCTTGTCCAG GCAGCTCAGA TGCTTCAGTC AGACCCTTAC
TCAGTGCCTG CTCGAGATTA TCTAATTGAT GGGTCAAGGG GCATCCTCTC TGGAACATCA
GACCTGCTCC TTACCTTCGA TGAGGCTGAG GTCCGTAAAA TTATTAGAGT TTGCAAAGGA
ATTTTGGAAT ATCTTACAGT GGCAGAGGTG GTGGAGACTA TGGAAGATTT GGTCACTTAC
ACAAAGAATC TTGGGCCAGG AATGACTAAG ATGGCCAAGA TGATTGACGA GAGACAGCAG
GAGCTCACTC ACCAGGAGCA CCGAGTGATG TTGGTGAACT CGATGAACAC CGTGAAAGAG
TTGCTGCCAG TTCTCATTTC AGCTATGAAG ATTTTTGTAA CAACTAAAAA CTCAAAAAAC
CAAGGCATAG AGGAAGCTTT AAAAAATCGC AATTTTACTG TAGAAAAAAT GAGTGCTGAA
ATTAATGAGA TAATTCGTGT GTTACAACTC ACCTCTTGGG ATGAAGATGC CTGGGCCAGC
AAGGACACTG AAGCCATGAA GAGAGCATTG GCCTCCATAG ACTCCAAACT GAACCAGGCC
AAAGGTTGGC TCCGTGACCC TAGTGCCTCC CCAGGGGATG CTGGTGAGCA GGCCATCAGA
CAGATCTTAG ATGAAGCTGG AAAAGTTGGT GAACTCTGTG CAGGCAAAGA ACGCAGGGAG
ATTCTGGGAA CTTGCAAAAT GCTAGGGCAG ATGACTGATC AAGTGGCTGA CCTCCGTGCC
AGAGGACAAG GATCCTCACC GGTGGCCATG CAGAAAGCTC AGCAGGTATC TCAGGGTCTG
GATGTGCTCA CAGCAAAAGT GGAAAATGCA GCTCGCAAGC TGGAAGCCAT GACCAACTCA
AAGCAGAGCA TTGCAAAGAA GATCGATGCT GCTCAGAACT GGCTTGCAGA TCCAAATGGT
GGACCGGAAG GAGAAGAGCA GATTCGAGGT GCTTTGGCTG AAGCTCGGAA AATAGCAGAA
TTATGTGATG ATCCTAAAGA AAGAGATGAC ATTCTACGTT CCCTTGGGGA AATATCTGCT
CTGACTTCTA AATTAGCAGA TCTACGAAGA CAGGGGAAAG GAGATTCTCC AGAGGCTCGA
GCCTTGGCCA AACAGGTGGC CACGGCCCTG CAGAACCTGC AGACCAAAAC CAACCGGGCT
GTGGCCAACA GCAGACCGGC CAAAGCAGCT GTACACCTTG AGGGCAAGAT TGAGCAAGCA
CAGCGGTGGA TTGATAATCC CACAGTGGAT GACCGTGGAG TCGGTCAGGC TGCCATCCGG
GGGCTTGTGG CCGAAGGGCA TCGTCTGGCT AATGTTATGA TGGGGCCTTA TCGGCAAGAT
CTTCTCGCCA AGTGTGACCG AGTGGACCAG CTGACAGCCC AGCTGGCTGA CCTGGCTGCC
AGAGGGGAAG GGGAGAGTCC TCAGGCACGA GCACTTGCAT CTCAGCTCCA AGACTCCTTA
AAGGATCTAA AAGCTCGGAT GCAGGAGGCC ATGACTCAGG AAGTGTCAGA TGTTTTCAGC
GATACCACAA CTCCCATCAA GCTGTTGGCA GTGGCAGCCA CGGCGCCTCC TGATGCGCCT
AACAGGGAAG AGGTATTTGA TGAGAGGGCA GCTAACTTTG AAAACCATTC AGGAAAGCTT
GGTGCTACGG CCGAGAAGGC GGCTGCGGTT GGTACTGCTA ATAAATCAAC AGTGGAAGGC
ATTCAGGCCT CAGTGAAGAC GGCCCGAGAA CTCACACCCC AGGTGGTCTC GGCTGCTCGT
ATCTTACTTA GGAACCCTGG AAATCAAGCT GCTTATGAAC ATTTTGAGAC CATGAAGAAC
CAGTGGATCG ATAATGTTGA AAAAATGACA GGGCTGGTGG ACGAAGCCAT TGATACCAAA
TCTCTGTTGG ATGCTTCAGA AGAAGCAATT AAAAAAGACC TGGACAAGTG CAAGGTAGCT
ATGGCCAACA TTCAGCCTCA GATGCTGGTT GCTGGGGCAA CCAGTATTGC TCGTCGGGCC
AACCGGATCC TGCTGGTGGC TAAGAGGGAG GTGGAGAATT CCGAGGATCC CAAGTTCCGT
GAGGCTGTGA AAGCTGCCTC TGATGAATTG AGCAAAACCA TCTCCCCGAT GGTGATGGAT
GCAAAAGCTG TGGCTGGAAA CATTTCCGAC CCTGGACTGC AAAAGAGCTT CCTGGACTCA
GGATATCGGA TCCTGGGAGC TGTGGCCAAG GTCAGAGAAG CCTTCCAACC TCAGGAGCCT
GACTTCCCGC CGCCTCCACC AGACCTTGAA CAACTCCGAC TAACAGATGA GCTTGCTCCT
CCCAAACCAC CTCTGCCTGA AGGTGAGGTC CCTCCACCTA GGCCTCCACC ACCAGAGGAA
AAGGATGAAG AGTTCCCTGA GCAGAAGGCC GGGGAGGTGA TTAACCAGCC AATGATGATG
GCTGCCAGAC AGCTCCATGA TGAAGCTCGC AAATGGTCCA GCAAGGGCAA TGACATCATT
GCAGCAGCCA AGCGCATGGC TCTGCTGATG GCTGAGATGT CTCGGCTGGT AAGAGGGGGC
AGTGGTACCA AGCGGGCACT CATTCAGTGT GCCAAGGACA TCGCCAAGGC CTCAGATGAG
GTGACTCGGT TGGCCAAGGA GGTTGCCAAG CAGTGCACAG ATAAACGGAT TAGAACCAAC
CTCTTACAGG TATGTGAGCG AATCCCAACC ATAAGCACCC AGCTCAAAAT CCTGTCCACA
GTGAAGGCCA CCATGCTGGG CCGGACCAAC ATCAGTGATG AGGAGTCTGA GCAGGCCACA
GAGATGCTGG TTCACAATGC CCAGAACCTC ATGCAGTCTG TGAAGGAGAC TGTGCGGGAA
GCTGAAGCTG CTTCAATCAA AATTCGAACA GATGCTGGAT TTACACTGCG CTGGGTTAGA
AAGACTCCCT GGTACCAGTA G
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_003364.1
CDS95..3295
Misc Feature(1)2..4(+)
Misc Feature(2)101..3292(+)
Misc Feature(3)347..349(+)
Misc Feature(4)392..394(+)
Misc Feature(5)956..958(+)
Misc Feature(6)962..964(+)
Misc Feature(7)1904..1906(+)
Misc Feature(8)2168..2170(+)
Misc Feature(9)2255..2257(+)
Misc Feature(10)2558..2560(+)
Misc Feature(11)3191..3193(+)
Misc Feature(12)3227..3229(+)
Misc Feature(13)3287..3289(+)
Exon (1)1..262
Gene:VCL
Gene Synonym:
Exon (2)263..333
Gene:VCL
Gene Synonym:
Exon (3)334..484
Gene:VCL
Gene Synonym:
Exon (4)485..593
Gene:VCL
Gene Synonym:
Exon (5)594..716
Gene:VCL
Gene Synonym:
Exon (6)717..877
Gene:VCL
Gene Synonym:
Exon (7)878..968
Gene:VCL
Gene Synonym:
Exon (8)969..1116
Gene:VCL
Gene Synonym:
Exon (9)1117..1270
Gene:VCL
Gene Synonym:
Exon (10)1271..1446
Gene:VCL
Gene Synonym:
Exon (11)1447..1637
Gene:VCL
Gene Synonym:
Exon (12)1638..1837
Gene:VCL
Gene Synonym:
Exon (13)1838..1966
Gene:VCL
Gene Synonym:
Exon (14)1967..2116
Gene:VCL
Gene Synonym:
Exon (15)2117..2225
Gene:VCL
Gene Synonym:
Exon (16)2226..2528
Gene:VCL
Gene Synonym:
Exon (17)2529..2653
Gene:VCL
Gene Synonym:
Exon (18)2654..2839
Gene:VCL
Gene Synonym:
Exon (19)2840..3043
Gene:VCL
Gene Synonym:
Exon (20)3044..3148
Gene:VCL
Gene Synonym:
Exon (21)3149..5286
Gene:VCL
Gene Synonym:
Translation