The following VWF gene sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the VWF gene which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
||ORF Nucleotide Sequence (Length: 8442bp)
||pcDNA3.1+/C-(K)DYK or customized vector
|Tag on pcDNA3.1+/C-(K)DYK
||C terminal DYKDDDDK tags
|ORF Insert Method
||CloneEZ® Seamless cloning technology
||Homo sapiens (human)
||von Willebrand factor preproprotein
||REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from AC005845.13, X04385.1,
DB293903.1, M10321.1, BQ898017.1 and BG951111.1.
This sequence is a reference standard in the RefSeqGene project.
On Mar 5, 2006 this sequence version replaced gi:9257255.
Summary: The glycoprotein encoded by this gene functions as both an
antihemophilic factor carrier and a platelet-vessel wall mediator
in the blood coagulation system. It is crucial to the hemostasis
process. Mutations in this gene or deficiencies in this protein
result in von Willebrand's disease. An unprocessed pseudogene has
been found on chromosome 22. [provided by RefSeq, Jul 2008].
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
Transcript exon combination :: X04385.1 [ECO:0000332]
RNAseq introns :: mixed/partial sample support