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XPA cDNA ORF clone, Homo sapiens (human)

Gene Symbol XPA
Entrez Gene ID 7507
Full Name xeroderma pigmentosum, complementation group A
Synonyms XP1, XPAC
General protein information
Preferred Names
DNA repair protein complementing XP-A cells
Names
DNA repair protein complementing XP-A cells
excision repair-controlling
xeroderma pigmentosum group A-complementing protein
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

9

9q22.3

Summary This gene encodes a zinc finger protein involved in DNA excision repair. The encoded protein is part of the NER (nucleotide excision repair) complext which is responsible for repair of UV radiation-induced photoproducts and DNA adducts induced by chemical carcinogens. Mutations in this gene are associated with xeroderma pigmentosum complementation group A. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2009]. lac of sum
Disorder MIM:

611153

Disorder Html: Xeroderma pigmentosum, group A, 278700 (3)

mRNA and Protein(s)

mRNA Protein Name
XM_011518988 XP_011517290 DNA repair protein complementing XP-A cells isoform X1
XM_006717278 XP_006717341 DNA repair protein complementing XP-A cells isoform X2
NM_000380 NP_000371 DNA repair protein complementing XP-A cells



Homo sapiens (human) XPA NP_000371.1
Pan troglodytes (chimpanzee) XPA XP_001156167.2
Macaca mulatta (Rhesus monkey) XPA XP_001114093.1
Canis lupus familiaris (dog) XPA XP_538745.2
Bos taurus (cattle) XPA NP_001033770.1
Mus musculus (house mouse) Xpa NP_035858.2
Rattus norvegicus (Norway rat) Xpa NP_001100126.1
Gallus gallus (chicken) XPA NP_990184.1
Danio rerio (zebrafish) xpa NP_956765.1
Drosophila melanogaster (fruit fly) Xpac NP_476866.1
Caenorhabditis elegans xpa-1 NP_492025.1
Xenopus (Silurana) tropicalis (western clawed frog) xpa NP_001016736.1


GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following XPA gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the XPA cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu61349 XM_011518988 PREDICTED: Homo sapiens xeroderma pigmentosum, complementation group A (XPA), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $139.30
$199.00
OHu43502 XM_006717278 PREDICTED: Homo sapiens xeroderma pigmentosum, complementation group A (XPA), transcript variant X3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $139.30
$199.00
OHu18921
NM_000380 Homo sapiens xeroderma pigmentosum, complementation group A (XPA), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$154.50-$216.30
$309.00
Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone 30% OFF
2-4 Clone 40% OFF
5 or more Clone 50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu61349
Clone ID Related Accession (Same CDS sequence) XM_011518988
Accession Version XM_011518988.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 822bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product DNA repair protein complementing XP-A cells isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_008470.20) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
ATGGCGGCGG CCGACGGGGC TTTGCCGGAG GCGGCGGCTT TAGAGCAACC CGCGGAGCTG 
CCTGCCTCGG TGCGGGCGAG TATCGAGCGG AAGCGGCAGC GGGCACTGAT GCTGCGCCAG
GCCCGGCTGG CTGCCCGGCC CTACTCGGCG ACGGCGGCTG CGGCTACTGG AGGCATGGCT
AATGTAAAAG CAGCCCCAAA GATAATTGAC ACAGGAGGAG GCTTCATTTT AGAAGAGGAA
GAAGAAGAAG AACAGAAAAT TGGAAAAGTT GTTCATCAAC CAGGACCTGT TATGGAATTT
GATTATGTAA TATGCGAAGA ATGTGGGAAA GAATTTATGG ATTCTTATCT TATGAACCAC
TTTGATTTGC CAACTTGTGA TAACTGCAGA GATGCTGATG ATAAACACAA GCTTATAACC
AAAACAGAGG CAAAACAAGA ATATCTTCTG AAAGACTGTG ATTTAGAAAA AAGAGAGCCA
CCTCTTAAAT TTATTGTGAA GAAGAATCCA CATCATTCAC AATGGGGTGA TATGAAACTC
TACTTAAAGT TACAGATTGT GAAGAGGTCT CTTGAAGTTT GGGGTAGTCA AGAAGCATTA
GAAGAAGCAA AGGAAGTCCG ACAGGAAAAC CGAGAAAAAA TGAAACAGAA GAAATTTGAT
AAAAAAGTAA AAGAATTGCG GCGAGCAGTA AGAAGCAGCG TGTGGAAAAG GGAGACGATT
GTTCATCAAC ATGAGTATGG ACCAGAAGAA AACCTAGAAG ATGACATGTA CCGTGCCATC
CCCACTGAAG CTGGAACCCT TCCCGAGTTC CATCTGGACT AG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011517290.1
CDS112..933
Misc Feature(1)409..510(+)
Misc Feature(2)424..885(+)
Misc Feature(3)511..669(+)
Translation

Target ORF information:

RefSeq Version XM_011518988
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens xeroderma pigmentosum, complementation group A (XPA), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011518988

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
ATGGCGGCGG CCGACGGGGC TTTGCCGGAG GCGGCGGCTT TAGAGCAACC CGCGGAGCTG 
CCTGCCTCGG TGCGGGCGAG TATCGAGCGG AAGCGGCAGC GGGCACTGAT GCTGCGCCAG
GCCCGGCTGG CTGCCCGGCC CTACTCGGCG ACGGCGGCTG CGGCTACTGG AGGCATGGCT
AATGTAAAAG CAGCCCCAAA GATAATTGAC ACAGGAGGAG GCTTCATTTT AGAAGAGGAA
GAAGAAGAAG AACAGAAAAT TGGAAAAGTT GTTCATCAAC CAGGACCTGT TATGGAATTT
GATTATGTAA TATGCGAAGA ATGTGGGAAA GAATTTATGG ATTCTTATCT TATGAACCAC
TTTGATTTGC CAACTTGTGA TAACTGCAGA GATGCTGATG ATAAACACAA GCTTATAACC
AAAACAGAGG CAAAACAAGA ATATCTTCTG AAAGACTGTG ATTTAGAAAA AAGAGAGCCA
CCTCTTAAAT TTATTGTGAA GAAGAATCCA CATCATTCAC AATGGGGTGA TATGAAACTC
TACTTAAAGT TACAGATTGT GAAGAGGTCT CTTGAAGTTT GGGGTAGTCA AGAAGCATTA
GAAGAAGCAA AGGAAGTCCG ACAGGAAAAC CGAGAAAAAA TGAAACAGAA GAAATTTGAT
AAAAAAGTAA AAGAATTGCG GCGAGCAGTA AGAAGCAGCG TGTGGAAAAG GGAGACGATT
GTTCATCAAC ATGAGTATGG ACCAGAAGAA AACCTAGAAG ATGACATGTA CCGTGCCATC
CCCACTGAAG CTGGAACCCT TCCCGAGTTC CATCTGGACT AG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu43502
Clone ID Related Accession (Same CDS sequence) XM_006717278
Accession Version XM_006717278.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 789bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product DNA repair protein complementing XP-A cells isoform X2
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_008470.20) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
ATGGCGGCGG CCGACGGGGC TTTGCCGGAG GCGGCGGCTT TAGAGCAACC CGCGGAGCTG 
CCTGCCTCGG TGCGGGCGAG TATCGAGCGG AAGCGGCAGC GGGCACTGAT GCTGCGCCAG
GCCCGGCTGG CTGCCCGGCC CTACTCGGCG ACGGCGGCTG CGGCTACTGG AGGCATGGCT
AATGTAAAAG CAGCCCCAAA GATAATTGAC ACAGGAGGAG GCTTCATTTT AGAAGAGGAA
GAAGAAGAAG AACAGAAAAT TGGAAAAGTT GTTCATCAAC CAGGACCTGT TATGGAATTT
GATTATGTAA TATGCGAAGA ATGTGGGAAA GAATTTATGG ATTCTTATCT TATGAACCAC
TTTGATTTGC CAACTTGTGA TAACTGCAGA GATGCTGATG ATAAACACAA GCTTATAACC
AAAACAGAGG CAAAACAAGA ATATCTTCTG AAAGACTGTG ATTTAGAAAA AAGAGAGCCA
CCTCTTAAAT TTATTGTGAA GAAGAATCCA CATCATTCAC AATGGGGTGA TATGAAACTC
TACTTAAAGT TACAGATTGT GAAGAGGTCT CTTGAAGTTT GGGGTAGTCA AGAAGCATTA
GAAGAAGCAA AGGAAGTCCG ACAGGAAAAC CGAGAAAAAA TGAAACAGAA GAAATTTGAT
AAAAAAGTAA AAGAATTGCG GCGAGCAGTA AGAAGCAGCG TGTGGAAAAG GGAGACGATT
GTTCATCAAC ATGAGTATGG ACCAGAAGAA AACCTAGAAG ATGACATGTA CCCTTTGAAA
TATCAGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_006717341.1
CDS112..900
Misc Feature(1)409..510(+)
Misc Feature(2)424..882(+)
Misc Feature(3)511..669(+)
Translation

Target ORF information:

RefSeq Version XM_006717278
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens xeroderma pigmentosum, complementation group A (XPA), transcript variant X3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_006717278

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
ATGGCGGCGG CCGACGGGGC TTTGCCGGAG GCGGCGGCTT TAGAGCAACC CGCGGAGCTG 
CCTGCCTCGG TGCGGGCGAG TATCGAGCGG AAGCGGCAGC GGGCACTGAT GCTGCGCCAG
GCCCGGCTGG CTGCCCGGCC CTACTCGGCG ACGGCGGCTG CGGCTACTGG AGGCATGGCT
AATGTAAAAG CAGCCCCAAA GATAATTGAC ACAGGAGGAG GCTTCATTTT AGAAGAGGAA
GAAGAAGAAG AACAGAAAAT TGGAAAAGTT GTTCATCAAC CAGGACCTGT TATGGAATTT
GATTATGTAA TATGCGAAGA ATGTGGGAAA GAATTTATGG ATTCTTATCT TATGAACCAC
TTTGATTTGC CAACTTGTGA TAACTGCAGA GATGCTGATG ATAAACACAA GCTTATAACC
AAAACAGAGG CAAAACAAGA ATATCTTCTG AAAGACTGTG ATTTAGAAAA AAGAGAGCCA
CCTCTTAAAT TTATTGTGAA GAAGAATCCA CATCATTCAC AATGGGGTGA TATGAAACTC
TACTTAAAGT TACAGATTGT GAAGAGGTCT CTTGAAGTTT GGGGTAGTCA AGAAGCATTA
GAAGAAGCAA AGGAAGTCCG ACAGGAAAAC CGAGAAAAAA TGAAACAGAA GAAATTTGAT
AAAAAAGTAA AAGAATTGCG GCGAGCAGTA AGAAGCAGCG TGTGGAAAAG GGAGACGATT
GTTCATCAAC ATGAGTATGG ACCAGAAGAA AACCTAGAAG ATGACATGTA CCCTTTGAAA
TATCAGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu18921
Clone ID Related Accession (Same CDS sequence) NM_000380
Accession Version NM_000380.3 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 822bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product DNA repair protein complementing XP-A cells
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from CB155090.1 and BC014965.1. This sequence is a reference standard in the RefSeqGene project. On Aug 29, 2007 this sequence version replaced gi:31543966. Transcript Variant: This variant (1) encodes a functional protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC014965.1, D14533.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
ATGGCGGCGG CCGACGGGGC TTTGCCGGAG GCGGCGGCTT TAGAGCAACC CGCGGAGCTG 
CCTGCCTCGG TGCGGGCGAG TATCGAGCGG AAGCGGCAGC GGGCACTGAT GCTGCGCCAG
GCCCGGCTGG CTGCCCGGCC CTACTCGGCG ACGGCGGCTG CGGCTACTGG AGGCATGGCT
AATGTAAAAG CAGCCCCAAA GATAATTGAC ACAGGAGGAG GCTTCATTTT AGAAGAGGAA
GAAGAAGAAG AACAGAAAAT TGGAAAAGTT GTTCATCAAC CAGGACCTGT TATGGAATTT
GATTATGTAA TATGCGAAGA ATGTGGGAAA GAATTTATGG ATTCTTATCT TATGAACCAC
TTTGATTTGC CAACTTGTGA TAACTGCAGA GATGCTGATG ATAAACACAA GCTTATAACC
AAAACAGAGG CAAAACAAGA ATATCTTCTG AAAGACTGTG ATTTAGAAAA AAGAGAGCCA
CCTCTTAAAT TTATTGTGAA GAAGAATCCA CATCATTCAC AATGGGGTGA TATGAAACTC
TACTTAAAGT TACAGATTGT GAAGAGGTCT CTTGAAGTTT GGGGTAGTCA AGAAGCATTA
GAAGAAGCAA AGGAAGTCCG ACAGGAAAAC CGAGAAAAAA TGAAACAGAA GAAATTTGAT
AAAAAAGTAA AAGAATTGCG GCGAGCAGTA AGAAGCAGCG TGTGGAAAAG GGAGACGATT
GTTCATCAAC ATGAGTATGG ACCAGAAGAA AACCTAGAAG ATGACATGTA CCGTAAGACT
TGTACTATGT GTGGCCATGA ACTGACATAT GAAAAAATGT GA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_000371.1
CDS118..939
Misc Feature(1)121..123(+)
Misc Feature(2)127..408(+)
Misc Feature(3)193..258(+)
Misc Feature(4)415..516(+)
Misc Feature(5)430..936(+)
Misc Feature(6)517..675(+)
Misc Feature(7)634..636(+)
Misc Feature(8)634..636(+)
Misc Feature(9)634..636(+)
Misc Feature(10)703..705(+)
Misc Feature(11)703..705(+)
Misc Feature(12)703..705(+)
Misc Feature(13)703..705(+)
Exon (1)1..289
Gene:XPA
Gene Synonym:
Exon (2)290..400
Gene:XPA
Gene Synonym:
Exon (3)401..506
Gene:XPA
Gene Synonym:
Exon (4)507..672
Gene:XPA
Gene Synonym:
Exon (5)673..790
Gene:XPA
Gene Synonym:
Exon (6)791..1469
Gene:XPA
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_000380
Organism Homo sapiens (human)
Definition Homo sapiens xeroderma pigmentosum, complementation group A (XPA), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_000380

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
ATGGCGGCGG CCGACGGGGC TTTGCCGGAG GCGGCGGCTT TAGAGCAACC CGCGGAGCTG 
CCTGCCTCGG TGCGGGCGAG TATCGAGCGG AAGCGGCAGC GGGCACTGAT GCTGCGCCAG
GCCCGGCTGG CTGCCCGGCC CTACTCGGCG ACGGCGGCTG CGGCTACTGG AGGCATGGCT
AATGTAAAAG CAGCCCCAAA GATAATTGAC ACAGGAGGAG GCTTCATTTT AGAAGAGGAA
GAAGAAGAAG AACAGAAAAT TGGAAAAGTT GTTCATCAAC CAGGACCTGT TATGGAATTT
GATTATGTAA TATGCGAAGA ATGTGGGAAA GAATTTATGG ATTCTTATCT TATGAACCAC
TTTGATTTGC CAACTTGTGA TAACTGCAGA GATGCTGATG ATAAACACAA GCTTATAACC
AAAACAGAGG CAAAACAAGA ATATCTTCTG AAAGACTGTG ATTTAGAAAA AAGAGAGCCA
CCTCTTAAAT TTATTGTGAA GAAGAATCCA CATCATTCAC AATGGGGTGA TATGAAACTC
TACTTAAAGT TACAGATTGT GAAGAGGTCT CTTGAAGTTT GGGGTAGTCA AGAAGCATTA
GAAGAAGCAA AGGAAGTCCG ACAGGAAAAC CGAGAAAAAA TGAAACAGAA GAAATTTGAT
AAAAAAGTAA AAGAATTGCG GCGAGCAGTA AGAAGCAGCG TGTGGAAAAG GGAGACGATT
GTTCATCAAC ATGAGTATGG ACCAGAAGAA AACCTAGAAG ATGACATGTA CCGTAAGACT
TGTACTATGT GTGGCCATGA ACTGACATAT GAAAAAATGT GA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

 
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