The following XRCC1 gene sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the XRCC1 gene which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
||ORF Nucleotide Sequence (Length: 1902bp)
||pcDNA3.1+/C-(K)DYK or customized vector
|Tag on pcDNA3.1+/C-(K)DYK
||C terminal DYKDDDDK tags
|ORF Insert Method
||CloneEZ® Seamless cloning technology
||Homo sapiens (human)
||DNA repair protein XRCC1
||REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from BP349667.1, AB208781.1 and
This sequence is a reference standard in the RefSeqGene project.
On Jun 19, 2008 this sequence version replaced gi:5454171.
Summary: The protein encoded by this gene is involved in the
efficient repair of DNA single-strand breaks formed by exposure to
ionizing radiation and alkylating agents. This protein interacts
with DNA ligase III, polymerase beta and poly (ADP-ribose)
polymerase to participate in the base excision repair pathway. It
may play a role in DNA processing during meiogenesis and
recombination in germ cells. A rare microsatellite polymorphism in
this gene is associated with cancer in patients of varying
radiosensitivity. [provided by RefSeq, Jul 2008].
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
Transcript exon combination :: AB208781.1, AK315332.1 [ECO:0000332]
RNAseq introns :: mixed/partial sample support
COMPLETENESS: full length.