||ORF Nucleotide Sequence (Length: 1902bp)
||pcDNA3.1-C-(k)DYK or customized vector
|Tag on pcDNA3.1-C-(k)DYK
||C terminal DYKDDDDK tags
|ORF Insert Method
||CloneEZ® Seamless cloning technology
||Homo sapiens (human)
||DNA repair protein XRCC1
||REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from BP349667.1, AB208781.1 and
This sequence is a reference standard in the RefSeqGene project.
On Jun 19, 2008 this sequence version replaced gi:5454171.
Summary: The protein encoded by this gene is involved in the
efficient repair of DNA single-strand breaks formed by exposure to
ionizing radiation and alkylating agents. This protein interacts
with DNA ligase III, polymerase beta and poly (ADP-ribose)
polymerase to participate in the base excision repair pathway. It
may play a role in DNA processing during meiogenesis and
recombination in germ cells. A rare microsatellite polymorphism in
this gene is associated with cancer in patients of varying
radiosensitivity. [provided by RefSeq, Jul 2008].
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
Transcript exon combination :: AB208781.1, AK315332.1 [ECO:0000332]
RNAseq introns :: mixed/partial sample support
COMPLETENESS: full length.