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XRCC3 cDNA ORF clone, Homo sapiens (human)

Gene Symbol XRCC3
Entrez Gene ID 7517
Full Name X-ray repair complementing defective repair in Chinese hamster cells 3
Synonyms CMM6
General protein information
Preferred Names
DNA repair protein XRCC3
Names
DNA repair protein XRCC3
X-ray repair cross-complementing protein 3
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

14

14q32.3

Summary This gene encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene functionally complements Chinese hamster irs1SF, a repair-deficient mutant that exhibits hypersensitivity to a number of different DNA-damaging agents and is chromosomally unstable. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008]. lac of sum
Disorder MIM:

600675

Disorder Html: {Melanoma, cutaneous malignant, susceptibility to, 6} (3); {Breast

mRNA and Protein(s)

mRNA Protein Name
XM_011537138 XP_011535440 DNA repair protein XRCC3 isoform X1
XM_005268046 XP_005268103 DNA repair protein XRCC3 isoform X1
NM_005432 NP_005423 DNA repair protein XRCC3
NM_001100118 NP_001093588 DNA repair protein XRCC3
NM_001100119 NP_001093589 DNA repair protein XRCC3



Homo sapiens (human) XRCC3 NP_001093588.1
Pan troglodytes (chimpanzee) XRCC3 XP_003314577.1
Macaca mulatta (Rhesus monkey) XRCC3 XP_001083970.1
Canis lupus familiaris (dog) XRCC3 XP_003435154.1
Bos taurus (cattle) XRCC3 NP_001071585.1
Mus musculus (house mouse) Xrcc3 NP_083151.1
Rattus norvegicus (Norway rat) LOC102551085 XP_006240711.1
Gallus gallus (chicken) XRCC3 NP_001006489.1
Danio rerio (zebrafish) xrcc3 NP_001013559.1
Drosophila melanogaster (fruit fly) spn-B NP_476740.1
Arabidopsis thaliana (thale cress) XRCC3 NP_851202.1
Xenopus (Silurana) tropicalis (western clawed frog) xrcc3 NP_001016141.1


GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following XRCC3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the XRCC3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu25309
XM_011537138 PREDICTED: Homo sapiens X-ray repair complementing defective repair in Chinese hamster cells 3 (XRCC3), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$49.50-$69.30
$99.00
OHu25309
XM_005268046 PREDICTED: Homo sapiens X-ray repair complementing defective repair in Chinese hamster cells 3 (XRCC3), transcript variant X2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$49.50-$69.30
$99.00
OHu25309
NM_005432 Homo sapiens X-ray repair complementing defective repair in Chinese hamster cells 3 (XRCC3), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$49.50-$69.30
$99.00
OHu25309
NM_001100118 Homo sapiens X-ray repair complementing defective repair in Chinese hamster cells 3 (XRCC3), transcript variant 3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$49.50-$69.30
$99.00
OHu25309
NM_001100119 Homo sapiens X-ray repair complementing defective repair in Chinese hamster cells 3 (XRCC3), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$49.50-$69.30
$99.00
Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone 30% OFF
2-4 Clone 40% OFF
5 or more Clone 50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu25309
Clone ID Related Accession (Same CDS sequence) NM_001100118 , NM_001100119 , NM_005432 , XM_005268046 , XM_011537138
Accession Version XM_011537138.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1041bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product DNA repair protein XRCC3 isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_026437.13) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
ATGGATTTGG ATCTACTGGA CCTGAATCCC AGAATTATTG CTGCAATTAA GAAAGCCAAA 
CTGAAATCGG TAAAGGAGGT TTTACACTTT TCTGGACCAG ACTTGAAGAG ACTGACCAAC
CTCTCCAGCC CCGAGGTCTG GCACTTGCTG AGAACGGCCT CCTTACACTT GCGGGGAAGC
AGCATCCTTA CAGCACTGCA GCTGCACCAG CAGAAGGAGC GGTTCCCCAC GCAGCACCAG
CGCCTGAGCC TGGGCTGCCC GGTGCTGGAC GCGCTGCTCC GCGGTGGCCT GCCCCTGGAC
GGCATCACTG AGCTGGCCGG ACGCAGCTCG GCAGGGAAGA CCCAGCTGGC GCTGCAGCTC
TGCCTGGCTG TGCAGTTCCC GCGGCAGCAC GGAGGCCTGG AGGCTGGAGC CGTCTACATC
TGCACGGAAG ACGCCTTCCC GCACAAGCGC CTGCAGCAGC TCATGGCCCA GCAGCCGCGG
CTGCGCACTG ACGTTCCAGG AGAGCTGCTT CAGAAGCTCC GATTTGGCAG CCAGATCTTC
ATCGAGCACG TGGCCGATGT GGACACCTTG TTGGAGTGTG TGAATAAGAA GGTCCCCGTA
CTGCTGTCTC GGGGCATGGC TCGCCTGGTG GTCATCGACT CGGTGGCAGC CCCATTCCGC
TGTGAATTTG ACAGCCAGGC CTCCGCCCCC AGGGCCAGGC ATCTGCAGTC CCTGGGGGCC
ACGCTGCGTG AGCTGAGCAG TGCCTTCCAG AGCCCTGTGC TGTGCATCAA CCAGGTGACA
GAGGCCATGG AGGAGCAGGG CGCAGCACAC GGGCCGCTGG GGTTCTGGGA CGAACGTGTT
TCCCCAGCCC TTGGCATAAC CTGGGCTAAC CAGCTCCTGG TGAGACTGCT GGCTGACCGG
CTCCGCGAGG AAGAGGCTGC CCTCGGCTGC CCAGCCCGGA CCCTGCGGGT GCTCTCTGCC
CCCCACCTGC CCCCCTCCTC CTGTTCCTAC ACGATCAGTG CCGAAGGGGT GCGAGGGACA
CCTGGGACCC AGTCCCACTG A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011535440.1
CDS364..1404
Misc Feature(1)367..1374(+)
Misc Feature(2)607..1377(+)
Misc Feature(3)682..705(+)
Misc Feature(4)688..1002(+)
Misc Feature(5)775..1110(+)
Misc Feature(6)988..1002(+)
Translation

Target ORF information:

RefSeq Version XM_011537138
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens X-ray repair complementing defective repair in Chinese hamster cells 3 (XRCC3), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011537138

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
ATGGATTTGG ATCTACTGGA CCTGAATCCC AGAATTATTG CTGCAATTAA GAAAGCCAAA 
CTGAAATCGG TAAAGGAGGT TTTACACTTT TCTGGACCAG ACTTGAAGAG ACTGACCAAC
CTCTCCAGCC CCGAGGTCTG GCACTTGCTG AGAACGGCCT CCTTACACTT GCGGGGAAGC
AGCATCCTTA CAGCACTGCA GCTGCACCAG CAGAAGGAGC GGTTCCCCAC GCAGCACCAG
CGCCTGAGCC TGGGCTGCCC GGTGCTGGAC GCGCTGCTCC GCGGTGGCCT GCCCCTGGAC
GGCATCACTG AGCTGGCCGG ACGCAGCTCG GCAGGGAAGA CCCAGCTGGC GCTGCAGCTC
TGCCTGGCTG TGCAGTTCCC GCGGCAGCAC GGAGGCCTGG AGGCTGGAGC CGTCTACATC
TGCACGGAAG ACGCCTTCCC GCACAAGCGC CTGCAGCAGC TCATGGCCCA GCAGCCGCGG
CTGCGCACTG ACGTTCCAGG AGAGCTGCTT CAGAAGCTCC GATTTGGCAG CCAGATCTTC
ATCGAGCACG TGGCCGATGT GGACACCTTG TTGGAGTGTG TGAATAAGAA GGTCCCCGTA
CTGCTGTCTC GGGGCATGGC TCGCCTGGTG GTCATCGACT CGGTGGCAGC CCCATTCCGC
TGTGAATTTG ACAGCCAGGC CTCCGCCCCC AGGGCCAGGC ATCTGCAGTC CCTGGGGGCC
ACGCTGCGTG AGCTGAGCAG TGCCTTCCAG AGCCCTGTGC TGTGCATCAA CCAGGTGACA
GAGGCCATGG AGGAGCAGGG CGCAGCACAC GGGCCGCTGG GGTTCTGGGA CGAACGTGTT
TCCCCAGCCC TTGGCATAAC CTGGGCTAAC CAGCTCCTGG TGAGACTGCT GGCTGACCGG
CTCCGCGAGG AAGAGGCTGC CCTCGGCTGC CCAGCCCGGA CCCTGCGGGT GCTCTCTGCC
CCCCACCTGC CCCCCTCCTC CTGTTCCTAC ACGATCAGTG CCGAAGGGGT GCGAGGGACA
CCTGGGACCC AGTCCCACTG A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu25309
Clone ID Related Accession (Same CDS sequence) NM_001100118 , NM_001100119 , NM_005432 , XM_005268046 , XM_011537138
Accession Version XM_005268046.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1041bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product DNA repair protein XRCC3 isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_026437.13) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
ATGGATTTGG ATCTACTGGA CCTGAATCCC AGAATTATTG CTGCAATTAA GAAAGCCAAA 
CTGAAATCGG TAAAGGAGGT TTTACACTTT TCTGGACCAG ACTTGAAGAG ACTGACCAAC
CTCTCCAGCC CCGAGGTCTG GCACTTGCTG AGAACGGCCT CCTTACACTT GCGGGGAAGC
AGCATCCTTA CAGCACTGCA GCTGCACCAG CAGAAGGAGC GGTTCCCCAC GCAGCACCAG
CGCCTGAGCC TGGGCTGCCC GGTGCTGGAC GCGCTGCTCC GCGGTGGCCT GCCCCTGGAC
GGCATCACTG AGCTGGCCGG ACGCAGCTCG GCAGGGAAGA CCCAGCTGGC GCTGCAGCTC
TGCCTGGCTG TGCAGTTCCC GCGGCAGCAC GGAGGCCTGG AGGCTGGAGC CGTCTACATC
TGCACGGAAG ACGCCTTCCC GCACAAGCGC CTGCAGCAGC TCATGGCCCA GCAGCCGCGG
CTGCGCACTG ACGTTCCAGG AGAGCTGCTT CAGAAGCTCC GATTTGGCAG CCAGATCTTC
ATCGAGCACG TGGCCGATGT GGACACCTTG TTGGAGTGTG TGAATAAGAA GGTCCCCGTA
CTGCTGTCTC GGGGCATGGC TCGCCTGGTG GTCATCGACT CGGTGGCAGC CCCATTCCGC
TGTGAATTTG ACAGCCAGGC CTCCGCCCCC AGGGCCAGGC ATCTGCAGTC CCTGGGGGCC
ACGCTGCGTG AGCTGAGCAG TGCCTTCCAG AGCCCTGTGC TGTGCATCAA CCAGGTGACA
GAGGCCATGG AGGAGCAGGG CGCAGCACAC GGGCCGCTGG GGTTCTGGGA CGAACGTGTT
TCCCCAGCCC TTGGCATAAC CTGGGCTAAC CAGCTCCTGG TGAGACTGCT GGCTGACCGG
CTCCGCGAGG AAGAGGCTGC CCTCGGCTGC CCAGCCCGGA CCCTGCGGGT GCTCTCTGCC
CCCCACCTGC CCCCCTCCTC CTGTTCCTAC ACGATCAGTG CCGAAGGGGT GCGAGGGACA
CCTGGGACCC AGTCCCACTG A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_005268103.1
CDS418..1458
Misc Feature(1)421..1428(+)
Misc Feature(2)661..1431(+)
Misc Feature(3)736..759(+)
Misc Feature(4)742..1056(+)
Misc Feature(5)829..1164(+)
Misc Feature(6)1042..1056(+)
Translation

Target ORF information:

RefSeq Version XM_005268046
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens X-ray repair complementing defective repair in Chinese hamster cells 3 (XRCC3), transcript variant X2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_005268046

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
ATGGATTTGG ATCTACTGGA CCTGAATCCC AGAATTATTG CTGCAATTAA GAAAGCCAAA 
CTGAAATCGG TAAAGGAGGT TTTACACTTT TCTGGACCAG ACTTGAAGAG ACTGACCAAC
CTCTCCAGCC CCGAGGTCTG GCACTTGCTG AGAACGGCCT CCTTACACTT GCGGGGAAGC
AGCATCCTTA CAGCACTGCA GCTGCACCAG CAGAAGGAGC GGTTCCCCAC GCAGCACCAG
CGCCTGAGCC TGGGCTGCCC GGTGCTGGAC GCGCTGCTCC GCGGTGGCCT GCCCCTGGAC
GGCATCACTG AGCTGGCCGG ACGCAGCTCG GCAGGGAAGA CCCAGCTGGC GCTGCAGCTC
TGCCTGGCTG TGCAGTTCCC GCGGCAGCAC GGAGGCCTGG AGGCTGGAGC CGTCTACATC
TGCACGGAAG ACGCCTTCCC GCACAAGCGC CTGCAGCAGC TCATGGCCCA GCAGCCGCGG
CTGCGCACTG ACGTTCCAGG AGAGCTGCTT CAGAAGCTCC GATTTGGCAG CCAGATCTTC
ATCGAGCACG TGGCCGATGT GGACACCTTG TTGGAGTGTG TGAATAAGAA GGTCCCCGTA
CTGCTGTCTC GGGGCATGGC TCGCCTGGTG GTCATCGACT CGGTGGCAGC CCCATTCCGC
TGTGAATTTG ACAGCCAGGC CTCCGCCCCC AGGGCCAGGC ATCTGCAGTC CCTGGGGGCC
ACGCTGCGTG AGCTGAGCAG TGCCTTCCAG AGCCCTGTGC TGTGCATCAA CCAGGTGACA
GAGGCCATGG AGGAGCAGGG CGCAGCACAC GGGCCGCTGG GGTTCTGGGA CGAACGTGTT
TCCCCAGCCC TTGGCATAAC CTGGGCTAAC CAGCTCCTGG TGAGACTGCT GGCTGACCGG
CTCCGCGAGG AAGAGGCTGC CCTCGGCTGC CCAGCCCGGA CCCTGCGGGT GCTCTCTGCC
CCCCACCTGC CCCCCTCCTC CTGTTCCTAC ACGATCAGTG CCGAAGGGGT GCGAGGGACA
CCTGGGACCC AGTCCCACTG A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu25309
Clone ID Related Accession (Same CDS sequence) NM_001100118 , NM_001100119 , NM_005432 , XM_005268046 , XM_011537138
Accession Version NM_005432.3 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1041bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product DNA repair protein XRCC3
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB041321.1, AK023646.1, BX161398.1 and BC002949.1. On Jul 26, 2007 this sequence version replaced gi:12408644. Transcript Variant: This variant (2) lacks a segment in the 5' UTR, compared to variant 1. Variants 1, 2 and 3 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC001036.1, AK023646.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
ATGGATTTGG ATCTACTGGA CCTGAATCCC AGAATTATTG CTGCAATTAA GAAAGCCAAA 
CTGAAATCGG TAAAGGAGGT TTTACACTTT TCTGGACCAG ACTTGAAGAG ACTGACCAAC
CTCTCCAGCC CCGAGGTCTG GCACTTGCTG AGAACGGCCT CCTTACACTT GCGGGGAAGC
AGCATCCTTA CAGCACTGCA GCTGCACCAG CAGAAGGAGC GGTTCCCCAC GCAGCACCAG
CGCCTGAGCC TGGGCTGCCC GGTGCTGGAC GCGCTGCTCC GCGGTGGCCT GCCCCTGGAC
GGCATCACTG AGCTGGCCGG ACGCAGCTCG GCAGGGAAGA CCCAGCTGGC GCTGCAGCTC
TGCCTGGCTG TGCAGTTCCC GCGGCAGCAC GGAGGCCTGG AGGCTGGAGC CGTCTACATC
TGCACGGAAG ACGCCTTCCC GCACAAGCGC CTGCAGCAGC TCATGGCCCA GCAGCCGCGG
CTGCGCACTG ACGTTCCAGG AGAGCTGCTT CAGAAGCTCC GATTTGGCAG CCAGATCTTC
ATCGAGCACG TGGCCGATGT GGACACCTTG TTGGAGTGTG TGAATAAGAA GGTCCCCGTA
CTGCTGTCTC GGGGCATGGC TCGCCTGGTG GTCATCGACT CGGTGGCAGC CCCATTCCGC
TGTGAATTTG ACAGCCAGGC CTCCGCCCCC AGGGCCAGGC ATCTGCAGTC CCTGGGGGCC
ACGCTGCGTG AGCTGAGCAG TGCCTTCCAG AGCCCTGTGC TGTGCATCAA CCAGGTGACA
GAGGCCATGG AGGAGCAGGG CGCAGCACAC GGGCCGCTGG GGTTCTGGGA CGAACGTGTT
TCCCCAGCCC TTGGCATAAC CTGGGCTAAC CAGCTCCTGG TGAGACTGCT GGCTGACCGG
CTCCGCGAGG AAGAGGCTGC CCTCGGCTGC CCAGCCCGGA CCCTGCGGGT GCTCTCTGCC
CCCCACCTGC CCCCCTCCTC CTGTTCCTAC ACGATCAGTG CCGAAGGGGT GCGAGGGACA
CCTGGGACCC AGTCCCACTG A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_005423.1
CDS381..1421
Misc Feature(1)297..299(+)
Misc Feature(2)381..383(+)
Misc Feature(3)384..1391(+)
Misc Feature(4)624..1394(+)
Misc Feature(5)699..722(+)
Misc Feature(6)705..1019(+)
Misc Feature(7)792..1127(+)
Misc Feature(8)1005..1019(+)
Misc Feature(9)1053..1055(+)
Exon (1)1..63
Gene:XRCC3
Gene Synonym:
Exon (2)64..120
Gene:XRCC3
Gene Synonym:
Exon (3)121..222
Gene:XRCC3
Gene Synonym:
Exon (4)223..435
Gene:XRCC3
Gene Synonym:
Exon (5)436..573
Gene:XRCC3
Gene Synonym:
Exon (6)574..786
Gene:XRCC3
Gene Synonym:
Exon (7)787..941
Gene:XRCC3
Gene Synonym:
Exon (8)942..1154
Gene:XRCC3
Gene Synonym:
Exon (9)1155..1201
Gene:XRCC3
Gene Synonym:
Exon (10)1202..2602
Gene:XRCC3
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_005432
Organism Homo sapiens (human)
Definition Homo sapiens X-ray repair complementing defective repair in Chinese hamster cells 3 (XRCC3), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_005432

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
ATGGATTTGG ATCTACTGGA CCTGAATCCC AGAATTATTG CTGCAATTAA GAAAGCCAAA 
CTGAAATCGG TAAAGGAGGT TTTACACTTT TCTGGACCAG ACTTGAAGAG ACTGACCAAC
CTCTCCAGCC CCGAGGTCTG GCACTTGCTG AGAACGGCCT CCTTACACTT GCGGGGAAGC
AGCATCCTTA CAGCACTGCA GCTGCACCAG CAGAAGGAGC GGTTCCCCAC GCAGCACCAG
CGCCTGAGCC TGGGCTGCCC GGTGCTGGAC GCGCTGCTCC GCGGTGGCCT GCCCCTGGAC
GGCATCACTG AGCTGGCCGG ACGCAGCTCG GCAGGGAAGA CCCAGCTGGC GCTGCAGCTC
TGCCTGGCTG TGCAGTTCCC GCGGCAGCAC GGAGGCCTGG AGGCTGGAGC CGTCTACATC
TGCACGGAAG ACGCCTTCCC GCACAAGCGC CTGCAGCAGC TCATGGCCCA GCAGCCGCGG
CTGCGCACTG ACGTTCCAGG AGAGCTGCTT CAGAAGCTCC GATTTGGCAG CCAGATCTTC
ATCGAGCACG TGGCCGATGT GGACACCTTG TTGGAGTGTG TGAATAAGAA GGTCCCCGTA
CTGCTGTCTC GGGGCATGGC TCGCCTGGTG GTCATCGACT CGGTGGCAGC CCCATTCCGC
TGTGAATTTG ACAGCCAGGC CTCCGCCCCC AGGGCCAGGC ATCTGCAGTC CCTGGGGGCC
ACGCTGCGTG AGCTGAGCAG TGCCTTCCAG AGCCCTGTGC TGTGCATCAA CCAGGTGACA
GAGGCCATGG AGGAGCAGGG CGCAGCACAC GGGCCGCTGG GGTTCTGGGA CGAACGTGTT
TCCCCAGCCC TTGGCATAAC CTGGGCTAAC CAGCTCCTGG TGAGACTGCT GGCTGACCGG
CTCCGCGAGG AAGAGGCTGC CCTCGGCTGC CCAGCCCGGA CCCTGCGGGT GCTCTCTGCC
CCCCACCTGC CCCCCTCCTC CTGTTCCTAC ACGATCAGTG CCGAAGGGGT GCGAGGGACA
CCTGGGACCC AGTCCCACTG A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu25309
Clone ID Related Accession (Same CDS sequence) NM_001100118 , NM_001100119 , NM_005432 , XM_005268046 , XM_011537138
Accession Version NM_001100118.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1041bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product DNA repair protein XRCC3
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB041321.1, BX161398.1 and BC002949.1. Transcript Variant: This variant (3) lacks a segment in the 5' UTR, compared to variant 1. Variants 1, 2 and 3 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC011725.2, BX161398.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
ATGGATTTGG ATCTACTGGA CCTGAATCCC AGAATTATTG CTGCAATTAA GAAAGCCAAA 
CTGAAATCGG TAAAGGAGGT TTTACACTTT TCTGGACCAG ACTTGAAGAG ACTGACCAAC
CTCTCCAGCC CCGAGGTCTG GCACTTGCTG AGAACGGCCT CCTTACACTT GCGGGGAAGC
AGCATCCTTA CAGCACTGCA GCTGCACCAG CAGAAGGAGC GGTTCCCCAC GCAGCACCAG
CGCCTGAGCC TGGGCTGCCC GGTGCTGGAC GCGCTGCTCC GCGGTGGCCT GCCCCTGGAC
GGCATCACTG AGCTGGCCGG ACGCAGCTCG GCAGGGAAGA CCCAGCTGGC GCTGCAGCTC
TGCCTGGCTG TGCAGTTCCC GCGGCAGCAC GGAGGCCTGG AGGCTGGAGC CGTCTACATC
TGCACGGAAG ACGCCTTCCC GCACAAGCGC CTGCAGCAGC TCATGGCCCA GCAGCCGCGG
CTGCGCACTG ACGTTCCAGG AGAGCTGCTT CAGAAGCTCC GATTTGGCAG CCAGATCTTC
ATCGAGCACG TGGCCGATGT GGACACCTTG TTGGAGTGTG TGAATAAGAA GGTCCCCGTA
CTGCTGTCTC GGGGCATGGC TCGCCTGGTG GTCATCGACT CGGTGGCAGC CCCATTCCGC
TGTGAATTTG ACAGCCAGGC CTCCGCCCCC AGGGCCAGGC ATCTGCAGTC CCTGGGGGCC
ACGCTGCGTG AGCTGAGCAG TGCCTTCCAG AGCCCTGTGC TGTGCATCAA CCAGGTGACA
GAGGCCATGG AGGAGCAGGG CGCAGCACAC GGGCCGCTGG GGTTCTGGGA CGAACGTGTT
TCCCCAGCCC TTGGCATAAC CTGGGCTAAC CAGCTCCTGG TGAGACTGCT GGCTGACCGG
CTCCGCGAGG AAGAGGCTGC CCTCGGCTGC CCAGCCCGGA CCCTGCGGGT GCTCTCTGCC
CCCCACCTGC CCCCCTCCTC CTGTTCCTAC ACGATCAGTG CCGAAGGGGT GCGAGGGACA
CCTGGGACCC AGTCCCACTG A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001093588.1
CDS324..1364
Misc Feature(1)240..242(+)
Misc Feature(2)324..326(+)
Misc Feature(3)327..1334(+)
Misc Feature(4)567..1337(+)
Misc Feature(5)642..665(+)
Misc Feature(6)648..962(+)
Misc Feature(7)735..1070(+)
Misc Feature(8)948..962(+)
Exon (1)1..63
Gene:XRCC3
Gene Synonym:
Exon (2)64..165
Gene:XRCC3
Gene Synonym:
Exon (3)166..378
Gene:XRCC3
Gene Synonym:
Exon (4)379..516
Gene:XRCC3
Gene Synonym:
Exon (5)517..729
Gene:XRCC3
Gene Synonym:
Exon (6)730..884
Gene:XRCC3
Gene Synonym:
Exon (7)885..1097
Gene:XRCC3
Gene Synonym:
Exon (8)1098..1144
Gene:XRCC3
Gene Synonym:
Exon (9)1145..2545
Gene:XRCC3
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_001100118
Organism Homo sapiens (human)
Definition Homo sapiens X-ray repair complementing defective repair in Chinese hamster cells 3 (XRCC3), transcript variant 3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001100118

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
ATGGATTTGG ATCTACTGGA CCTGAATCCC AGAATTATTG CTGCAATTAA GAAAGCCAAA 
CTGAAATCGG TAAAGGAGGT TTTACACTTT TCTGGACCAG ACTTGAAGAG ACTGACCAAC
CTCTCCAGCC CCGAGGTCTG GCACTTGCTG AGAACGGCCT CCTTACACTT GCGGGGAAGC
AGCATCCTTA CAGCACTGCA GCTGCACCAG CAGAAGGAGC GGTTCCCCAC GCAGCACCAG
CGCCTGAGCC TGGGCTGCCC GGTGCTGGAC GCGCTGCTCC GCGGTGGCCT GCCCCTGGAC
GGCATCACTG AGCTGGCCGG ACGCAGCTCG GCAGGGAAGA CCCAGCTGGC GCTGCAGCTC
TGCCTGGCTG TGCAGTTCCC GCGGCAGCAC GGAGGCCTGG AGGCTGGAGC CGTCTACATC
TGCACGGAAG ACGCCTTCCC GCACAAGCGC CTGCAGCAGC TCATGGCCCA GCAGCCGCGG
CTGCGCACTG ACGTTCCAGG AGAGCTGCTT CAGAAGCTCC GATTTGGCAG CCAGATCTTC
ATCGAGCACG TGGCCGATGT GGACACCTTG TTGGAGTGTG TGAATAAGAA GGTCCCCGTA
CTGCTGTCTC GGGGCATGGC TCGCCTGGTG GTCATCGACT CGGTGGCAGC CCCATTCCGC
TGTGAATTTG ACAGCCAGGC CTCCGCCCCC AGGGCCAGGC ATCTGCAGTC CCTGGGGGCC
ACGCTGCGTG AGCTGAGCAG TGCCTTCCAG AGCCCTGTGC TGTGCATCAA CCAGGTGACA
GAGGCCATGG AGGAGCAGGG CGCAGCACAC GGGCCGCTGG GGTTCTGGGA CGAACGTGTT
TCCCCAGCCC TTGGCATAAC CTGGGCTAAC CAGCTCCTGG TGAGACTGCT GGCTGACCGG
CTCCGCGAGG AAGAGGCTGC CCTCGGCTGC CCAGCCCGGA CCCTGCGGGT GCTCTCTGCC
CCCCACCTGC CCCCCTCCTC CTGTTCCTAC ACGATCAGTG CCGAAGGGGT GCGAGGGACA
CCTGGGACCC AGTCCCACTG A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu25309
Clone ID Related Accession (Same CDS sequence) NM_001100118 , NM_001100119 , NM_005432 , XM_005268046 , XM_011537138
Accession Version NM_001100119.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1041bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product DNA repair protein XRCC3
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB041321.1, AK022829.1, BX161398.1 and BC002949.1. This sequence is a reference standard in the RefSeqGene project. Transcript Variant: This variant (1) represents the longest transcript. Variants 1, 2 and 3 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## CDS exon combination :: BC001036.1, AK022829.1 [ECO:0000331] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
ATGGATTTGG ATCTACTGGA CCTGAATCCC AGAATTATTG CTGCAATTAA GAAAGCCAAA 
CTGAAATCGG TAAAGGAGGT TTTACACTTT TCTGGACCAG ACTTGAAGAG ACTGACCAAC
CTCTCCAGCC CCGAGGTCTG GCACTTGCTG AGAACGGCCT CCTTACACTT GCGGGGAAGC
AGCATCCTTA CAGCACTGCA GCTGCACCAG CAGAAGGAGC GGTTCCCCAC GCAGCACCAG
CGCCTGAGCC TGGGCTGCCC GGTGCTGGAC GCGCTGCTCC GCGGTGGCCT GCCCCTGGAC
GGCATCACTG AGCTGGCCGG ACGCAGCTCG GCAGGGAAGA CCCAGCTGGC GCTGCAGCTC
TGCCTGGCTG TGCAGTTCCC GCGGCAGCAC GGAGGCCTGG AGGCTGGAGC CGTCTACATC
TGCACGGAAG ACGCCTTCCC GCACAAGCGC CTGCAGCAGC TCATGGCCCA GCAGCCGCGG
CTGCGCACTG ACGTTCCAGG AGAGCTGCTT CAGAAGCTCC GATTTGGCAG CCAGATCTTC
ATCGAGCACG TGGCCGATGT GGACACCTTG TTGGAGTGTG TGAATAAGAA GGTCCCCGTA
CTGCTGTCTC GGGGCATGGC TCGCCTGGTG GTCATCGACT CGGTGGCAGC CCCATTCCGC
TGTGAATTTG ACAGCCAGGC CTCCGCCCCC AGGGCCAGGC ATCTGCAGTC CCTGGGGGCC
ACGCTGCGTG AGCTGAGCAG TGCCTTCCAG AGCCCTGTGC TGTGCATCAA CCAGGTGACA
GAGGCCATGG AGGAGCAGGG CGCAGCACAC GGGCCGCTGG GGTTCTGGGA CGAACGTGTT
TCCCCAGCCC TTGGCATAAC CTGGGCTAAC CAGCTCCTGG TGAGACTGCT GGCTGACCGG
CTCCGCGAGG AAGAGGCTGC CCTCGGCTGC CCAGCCCGGA CCCTGCGGGT GCTCTCTGCC
CCCCACCTGC CCCCCTCCTC CTGTTCCTAC ACGATCAGTG CCGAAGGGGT GCGAGGGACA
CCTGGGACCC AGTCCCACTG A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001093589.1
CDS418..1458
Misc Feature(1)334..336(+)
Misc Feature(2)418..420(+)
Misc Feature(3)421..1428(+)
Misc Feature(4)661..1431(+)
Misc Feature(5)736..759(+)
Misc Feature(6)742..1056(+)
Misc Feature(7)829..1164(+)
Misc Feature(8)1042..1056(+)
Exon (1)1..63
Gene:XRCC3
Gene Synonym:
Exon (2)64..157
Gene:XRCC3
Gene Synonym:
Exon (3)158..259
Gene:XRCC3
Gene Synonym:
Exon (4)260..472
Gene:XRCC3
Gene Synonym:
Exon (5)473..610
Gene:XRCC3
Gene Synonym:
Exon (6)611..823
Gene:XRCC3
Gene Synonym:
Exon (7)824..978
Gene:XRCC3
Gene Synonym:
Exon (8)979..1191
Gene:XRCC3
Gene Synonym:
Exon (9)1192..1238
Gene:XRCC3
Gene Synonym:
Exon (10)1239..2639
Gene:XRCC3
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_001100119
Organism Homo sapiens (human)
Definition Homo sapiens X-ray repair complementing defective repair in Chinese hamster cells 3 (XRCC3), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001100119

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
ATGGATTTGG ATCTACTGGA CCTGAATCCC AGAATTATTG CTGCAATTAA GAAAGCCAAA 
CTGAAATCGG TAAAGGAGGT TTTACACTTT TCTGGACCAG ACTTGAAGAG ACTGACCAAC
CTCTCCAGCC CCGAGGTCTG GCACTTGCTG AGAACGGCCT CCTTACACTT GCGGGGAAGC
AGCATCCTTA CAGCACTGCA GCTGCACCAG CAGAAGGAGC GGTTCCCCAC GCAGCACCAG
CGCCTGAGCC TGGGCTGCCC GGTGCTGGAC GCGCTGCTCC GCGGTGGCCT GCCCCTGGAC
GGCATCACTG AGCTGGCCGG ACGCAGCTCG GCAGGGAAGA CCCAGCTGGC GCTGCAGCTC
TGCCTGGCTG TGCAGTTCCC GCGGCAGCAC GGAGGCCTGG AGGCTGGAGC CGTCTACATC
TGCACGGAAG ACGCCTTCCC GCACAAGCGC CTGCAGCAGC TCATGGCCCA GCAGCCGCGG
CTGCGCACTG ACGTTCCAGG AGAGCTGCTT CAGAAGCTCC GATTTGGCAG CCAGATCTTC
ATCGAGCACG TGGCCGATGT GGACACCTTG TTGGAGTGTG TGAATAAGAA GGTCCCCGTA
CTGCTGTCTC GGGGCATGGC TCGCCTGGTG GTCATCGACT CGGTGGCAGC CCCATTCCGC
TGTGAATTTG ACAGCCAGGC CTCCGCCCCC AGGGCCAGGC ATCTGCAGTC CCTGGGGGCC
ACGCTGCGTG AGCTGAGCAG TGCCTTCCAG AGCCCTGTGC TGTGCATCAA CCAGGTGACA
GAGGCCATGG AGGAGCAGGG CGCAGCACAC GGGCCGCTGG GGTTCTGGGA CGAACGTGTT
TCCCCAGCCC TTGGCATAAC CTGGGCTAAC CAGCTCCTGG TGAGACTGCT GGCTGACCGG
CTCCGCGAGG AAGAGGCTGC CCTCGGCTGC CCAGCCCGGA CCCTGCGGGT GCTCTCTGCC
CCCCACCTGC CCCCCTCCTC CTGTTCCTAC ACGATCAGTG CCGAAGGGGT GCGAGGGACA
CCTGGGACCC AGTCCCACTG A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

 
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