The following RAB7A gene sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the RAB7A gene which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
||ORF Nucleotide Sequence (Length: 624bp)
||pcDNA3.1+/C-(K)DYK or customized vector
|Tag on pcDNA3.1+/C-(K)DYK
||C terminal DYKDDDDK tags
|ORF Insert Method
||CloneEZ® Seamless cloning technology
||Homo sapiens (human)
||ras-related protein Rab-7a
||REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from AU122058.1, AF498942.1,
BC008721.2, AK094449.1 and CA748697.1.
This sequence is a reference standard in the RefSeqGene project.
On Jan 13, 2004 this sequence version replaced gi:34147512.
Summary: RAB family members are small, RAS-related GTP-binding
proteins that are important regulators of vesicular transport. Each
RAB protein targets multiple proteins that act in exocytic /
endocytic pathways. This gene encodes a RAB family member that
regulates vesicle traffic in the late endosomes and also from late
endosomes to lysosomes. This encoded protein is also involved in
the cellular vacuolation of the VacA cytotoxin of Helicobacter
pylori. Mutations at highly conserved amino acid residues in this
gene have caused some forms of Charcot-Marie-Tooth (CMT) type 2
neuropathies. [provided by RefSeq, Jul 2008].
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
Transcript exon combination :: BC008721.2, BM910436.1 [ECO:0000332]
RNAseq introns :: single sample supports all introns
COMPLETENESS: complete on the 3' end.