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MAFK cDNA ORF clone, Homo sapiens (human)

Gene Symbol MAFK
Entrez Gene ID 7975
Full Name v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K
Synonyms NFE2U, P18
General protein information
Preferred Names
transcription factor MafK
Names
transcription factor MafK
nuclear factor erythroid-2, ubiquitous (p18)
basic-leucine zipper transcription factor MafK
erythroid transcription factor NF-E2 p18 subunit
v-maf musculoaponeurotic fibrosarcoma oncogene homolog K
v-maf avian musculoaponeurotic fibrosarcoma oncogene family, protein K
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

7

7p22.3

Summary The developmentally regulated expression of the globin genes depends on upstream regulatory elements termed locus control regions (LCRs). LCRs are associated with powerful enhancer activity that is mediated by the transcription factor NFE2 (nuclear factor erythroid-2). NFE2 recognition sites are also present in the gene promoters of 2 heme biosynthetic enzymes, porphobilinogen deaminase (PBGD; MIM 609806) and ferrochelatase (FECH; MIM 612386). NFE2 DNA-binding activity consists of a heterodimer containing an 18-kD Maf protein (MafF, MafG (MIM 602020), or MafK) and p45 (MIM 601490). Both subunits are members of the activator protein-1 superfamily of basic leucine zipper (bZIP) proteins (see MIM 165160). Maf homodimers suppress transcription at NFE2 sites.[supplied by OMIM, Nov 2008]. lac of sum
Disorder MIM:

600197


mRNA and Protein(s)

mRNA Protein Name
XM_005249851 XP_005249908 transcription factor MafK isoform X1
XM_006715773 XP_006715836 transcription factor MafK isoform X1
NM_002360 NP_002351 transcription factor MafK



Homo sapiens (human) MAFK NP_002351.1
Macaca mulatta (Rhesus monkey) LOC721769 XP_001117972.1
Canis lupus familiaris (dog) MAFK XP_003639134.1
Bos taurus (cattle) MAFK NP_001193229.1
Mus musculus (house mouse) Mafk NP_034887.1
Rattus norvegicus (Norway rat) Mafk NP_663706.2
Gallus gallus (chicken) MAFK NP_990087.1
Danio rerio (zebrafish) mafk NP_001002044.2
Drosophila melanogaster (fruit fly) maf-S NP_611500.1
Xenopus (Silurana) tropicalis (western clawed frog) mafk NP_001090663.1


The following MAFK gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MAFK cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu03039
XM_005249851 PREDICTED: Homo sapiens v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K (MAFK), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$49.50-$69.30
$99.00
OHu03039
XM_006715773 PREDICTED: Homo sapiens v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K (MAFK), transcript variant X2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$49.50-$69.30
$99.00
OHu03039
NM_002360 Homo sapiens v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K (MAFK), mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$49.50-$69.30
$99.00
Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone 30% OFF
2-4 Clone 40% OFF
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*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu03039
Clone ID Related Accession (Same CDS sequence) NM_002360 , XM_005249851 , XM_006715773
Accession Version XM_005249851.2 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 471bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product transcription factor MafK isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_007819.18) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 12, 2015 this sequence version replaced gi:530384988. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
ATGACGACTA ATCCCAAACC GAATAAGGCA TTAAAGGTCA AGAAGGAGGC GGGCGAGAAC 
GCCCCGGTGC TCAGCGATGA TGAGCTGGTG TCCATGTCGG TGCGGGAGCT GAACCAGCAC
CTGCGGGGTC TCACCAAGGA GGAGGTGACC CGCCTGAAGC AGCGTCGGCG CACACTCAAG
AACCGCGGCT ACGCGGCCAG CTGCCGCATC AAGCGGGTGA CGCAGAAGGA GGAGCTGGAG
CGGCAGCGCG TGGAGCTGCA GCAGGAGGTG GAGAAGCTGG CGCGTGAGAA CAGCAGCATG
CGGCTGGAGC TGGACGCCCT GCGCTCCAAG TACGAGGCGC TGCAGACCTT CGCGCGCACC
GTGGCCCGGG GACCTGTGGC GCCCTCCAAG GTGGCCACCA CCAGCGTCAT CACCATCGTC
AAGTCCACCG AGCTCTCCTC CACCTCCGTG CCCTTCTCGG CTGCATCCTA G

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_005249908.2
CDS256..726
Misc Feature(1)391..600(+)
Misc Feature(2)391..600(+)
Misc Feature(3)421..471(+)
Misc Feature(4)469..579(+)
Translation

Target ORF information:

RefSeq Version XM_005249851
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K (MAFK), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_005249851

ORF Insert Sequence:

1
61
121
181
241
301
361
421
ATGACGACTA ATCCCAAACC GAATAAGGCA TTAAAGGTCA AGAAGGAGGC GGGCGAGAAC 
GCCCCGGTGC TCAGCGATGA TGAGCTGGTG TCCATGTCGG TGCGGGAGCT GAACCAGCAC
CTGCGGGGTC TCACCAAGGA GGAGGTGACC CGCCTGAAGC AGCGTCGGCG CACACTCAAG
AACCGCGGCT ACGCGGCCAG CTGCCGCATC AAGCGGGTGA CGCAGAAGGA GGAGCTGGAG
CGGCAGCGCG TGGAGCTGCA GCAGGAGGTG GAGAAGCTGG CGCGTGAGAA CAGCAGCATG
CGGCTGGAGC TGGACGCCCT GCGCTCCAAG TACGAGGCGC TGCAGACCTT CGCGCGCACC
GTGGCCCGGG GACCTGTGGC GCCCTCCAAG GTGGCCACCA CCAGCGTCAT CACCATCGTC
AAGTCCACCG AGCTCTCCTC CACCTCCGTG CCCTTCTCGG CTGCATCCTA G

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu03039
Clone ID Related Accession (Same CDS sequence) NM_002360 , XM_005249851 , XM_006715773
Accession Version XM_006715773.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 471bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product transcription factor MafK isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_007819.18) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
ATGACGACTA ATCCCAAACC GAATAAGGCA TTAAAGGTCA AGAAGGAGGC GGGCGAGAAC 
GCCCCGGTGC TCAGCGATGA TGAGCTGGTG TCCATGTCGG TGCGGGAGCT GAACCAGCAC
CTGCGGGGTC TCACCAAGGA GGAGGTGACC CGCCTGAAGC AGCGTCGGCG CACACTCAAG
AACCGCGGCT ACGCGGCCAG CTGCCGCATC AAGCGGGTGA CGCAGAAGGA GGAGCTGGAG
CGGCAGCGCG TGGAGCTGCA GCAGGAGGTG GAGAAGCTGG CGCGTGAGAA CAGCAGCATG
CGGCTGGAGC TGGACGCCCT GCGCTCCAAG TACGAGGCGC TGCAGACCTT CGCGCGCACC
GTGGCCCGGG GACCTGTGGC GCCCTCCAAG GTGGCCACCA CCAGCGTCAT CACCATCGTC
AAGTCCACCG AGCTCTCCTC CACCTCCGTG CCCTTCTCGG CTGCATCCTA G

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_006715836.1
CDS265..735
Misc Feature(1)400..609(+)
Misc Feature(2)400..609(+)
Misc Feature(3)430..480(+)
Misc Feature(4)478..588(+)
Translation

Target ORF information:

RefSeq Version XM_006715773
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K (MAFK), transcript variant X2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_006715773

ORF Insert Sequence:

1
61
121
181
241
301
361
421
ATGACGACTA ATCCCAAACC GAATAAGGCA TTAAAGGTCA AGAAGGAGGC GGGCGAGAAC 
GCCCCGGTGC TCAGCGATGA TGAGCTGGTG TCCATGTCGG TGCGGGAGCT GAACCAGCAC
CTGCGGGGTC TCACCAAGGA GGAGGTGACC CGCCTGAAGC AGCGTCGGCG CACACTCAAG
AACCGCGGCT ACGCGGCCAG CTGCCGCATC AAGCGGGTGA CGCAGAAGGA GGAGCTGGAG
CGGCAGCGCG TGGAGCTGCA GCAGGAGGTG GAGAAGCTGG CGCGTGAGAA CAGCAGCATG
CGGCTGGAGC TGGACGCCCT GCGCTCCAAG TACGAGGCGC TGCAGACCTT CGCGCGCACC
GTGGCCCGGG GACCTGTGGC GCCCTCCAAG GTGGCCACCA CCAGCGTCAT CACCATCGTC
AAGTCCACCG AGCTCTCCTC CACCTCCGTG CCCTTCTCGG CTGCATCCTA G

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu03039
Clone ID Related Accession (Same CDS sequence) NM_002360 , XM_005249851 , XM_006715773
Accession Version NM_002360.3 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 471bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product transcription factor MafK
Comment VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AF059194.1 and AC093734.3. On Nov 23, 2005 this sequence version replaced gi:56699486. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF059194.1, CT002504.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
ATGACGACTA ATCCCAAACC GAATAAGGCA TTAAAGGTCA AGAAGGAGGC GGGCGAGAAC 
GCCCCGGTGC TCAGCGATGA TGAGCTGGTG TCCATGTCGG TGCGGGAGCT GAACCAGCAC
CTGCGGGGTC TCACCAAGGA GGAGGTGACC CGCCTGAAGC AGCGTCGGCG CACACTCAAG
AACCGCGGCT ACGCGGCCAG CTGCCGCATC AAGCGGGTGA CGCAGAAGGA GGAGCTGGAG
CGGCAGCGCG TGGAGCTGCA GCAGGAGGTG GAGAAGCTGG CGCGTGAGAA CAGCAGCATG
CGGCTGGAGC TGGACGCCCT GCGCTCCAAG TACGAGGCGC TGCAGACCTT CGCGCGCACC
GTGGCCCGGG GACCTGTGGC GCCCTCCAAG GTGGCCACCA CCAGCGTCAT CACCATCGTC
AAGTCCACCG AGCTCTCCTC CACCTCCGTG CCCTTCTCGG CTGCATCCTA G

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_002351.1
CDS212..682
Misc Feature(1)284..286(+)
Misc Feature(2)347..556(+)
Misc Feature(3)347..556(+)
Misc Feature(4)362..439(+)
Misc Feature(5)377..427(+)
Misc Feature(6)425..535(+)
Misc Feature(7)446..490(+)
Exon (1)1..167
Gene:MAFK
Gene Synonym:
Exon (2)168..247
Gene:MAFK
Gene Synonym:
Exon (3)248..3350
Gene:MAFK
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_002360
Organism Homo sapiens (human)
Definition Homo sapiens v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K (MAFK), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_002360

ORF Insert Sequence:

1
61
121
181
241
301
361
421
ATGACGACTA ATCCCAAACC GAATAAGGCA TTAAAGGTCA AGAAGGAGGC GGGCGAGAAC 
GCCCCGGTGC TCAGCGATGA TGAGCTGGTG TCCATGTCGG TGCGGGAGCT GAACCAGCAC
CTGCGGGGTC TCACCAAGGA GGAGGTGACC CGCCTGAAGC AGCGTCGGCG CACACTCAAG
AACCGCGGCT ACGCGGCCAG CTGCCGCATC AAGCGGGTGA CGCAGAAGGA GGAGCTGGAG
CGGCAGCGCG TGGAGCTGCA GCAGGAGGTG GAGAAGCTGG CGCGTGAGAA CAGCAGCATG
CGGCTGGAGC TGGACGCCCT GCGCTCCAAG TACGAGGCGC TGCAGACCTT CGCGCGCACC
GTGGCCCGGG GACCTGTGGC GCCCTCCAAG GTGGCCACCA CCAGCGTCAT CACCATCGTC
AAGTCCACCG AGCTCTCCTC CACCTCCGTG CCCTTCTCGG CTGCATCCTA G

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

 
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