The following CUBN gene sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CUBN gene which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
||ORF Nucleotide Sequence (Length: 10872bp)
||pcDNA3.1+/C-(K)DYK or customized vector
|Tag on pcDNA3.1+/C-(K)DYK
||C terminal DYKDDDDK tags
|ORF Insert Method
||CloneEZ® Seamless cloning technology
||Homo sapiens (human)
||REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from BP271329.1, AF034611.1,
AC067747.7, BP270790.1, AL731551.9 and AL365215.23.
This sequence is a reference standard in the RefSeqGene project.
On Feb 23, 2007 this sequence version replaced gi:21536291.
Summary: Cubilin (CUBN) acts as a receptor for intrinsic
factor-vitamin B12 complexes. The role of receptor is supported by
the presence of 27 CUB domains. Cubulin is located within the
epithelium of intestine and kidney. Mutations in CUBN may play a
role in autosomal recessive megaloblastic anemia. [provided by
RefSeq, Jul 2008].
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
Transcript exon combination :: AF034611.1 [ECO:0000332]
RNAseq introns :: mixed/partial sample support
COMPLETENESS: complete on the 3' end.