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CFHR5 complement factor H-related 5 [Homo sapiens (human)]

Gene Symbol CFHR5
Entrez Gene ID 81494
Full Name complement factor H-related 5
Synonyms CFHL5, CFHR5D, FHR-5, FHR5
General protein information
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

1

1q31.3

Summary This gene is a member of a small complement factor H (CFH) gene cluster on chromosome 1. Each member of this gene family contains multiple short consensus repeats (SCRs) typical of regulators of complement activation. The protein encoded by this gene has nine SCRs with the first two repeats having heparin binding properties, a region within repeats 5-7 having heparin binding and C reactive protein binding properties, and the C-terminal repeats being similar to a complement component 3 b (C3b) binding domain. This protein co-localizes with C3, binds C3b in a dose-dependent manner, and is recruited to tissues damaged by C-reactive protein. Allelic variations in this gene have been associated, but not causally linked, with two different forms of kidney disease: membranoproliferative glomerulonephritis type II (MPGNII) and hemolytic uraemic syndrome (HUS). [provided by RefSeq, Jan 2010]. lac of sum
Disorder MIM:

608593

Disorder Html:
CloneID RefSeq Accession Definition **Vector *Turnaround time Price
OHu72899 XM_011510020 PREDICTED: Homo sapiens complement factor H-related 5 (CFHR5), transcript variant X1, mRNA. pcDNA3.1-C-(k)DYK Not in stock 7-9 Starting from $99.00
OHu22543 NM_030787 Homo sapiens complement factor H-related 5 (CFHR5), mRNA. pcDNA3.1-C-(k)DYK Not in stock 7-9 Starting from $99.00

*Business Day
**You may select a custom vector to replace pcDNA3.1-C-(k)DYK after clone is added to cart.



CloneID OHu72899D
Sequence Information ORF Nucleotide Sequence (Length: 1719bp)
Protein sequence
SNP
Vector pcDNA3.1-C-(k)DYK or customized vector
Clone information Clone Map
Tag on pcDNA3.1-C-(k)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product complement factor H-related protein 5 isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_004487.20) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
ATGGTGAAGC CTTTGAGACA GAAGAGAAAC CAGGAGAATG TGGTGTTCCA TAGACCATGT 
GAAGCAGGAA CACTTTGTGA TTTTCCAAAA ATACACCATG GATTTCTGTA TGATGAAGAA
GATTATAACC CTTTTTCCCA AGTTCCTACA GGGGAAGTTT TCTATTACTC CTGTGAATAT
AATTTTGTGT CTCCTTCAAA ATCCTTTTGG ACTCGCATAA CATGCACAGA AGAAGGATGG
TCACCAACAC CGAAGTGTCT CAGAATGTGT TCCTTTCCTT TTGTGAAAAA TGGTCATTCT
GAATCTTCAG GACTAATACA TCTGGAAGGT GATACTGTAC AAATTATTTG CAACACAGGA
TACAGCCTTC AAAACAATGA GAAAAACATT TCGTGTGTAG AACGGGGCTG GTCCACTCCT
CCCATATGCA GCTTCACTAA AGGAGAATGT CATGTTCCAA TTTTAGAAGC CAATGTAGAT
GCTCAGCCAA AAAAAGAAAG CTACAAAGTT GGAGACGTGT TGAAATTCTC CTGCAGAAAA
AATCTTATAA GAGTTGGATC AGACTCAGTT CAATGTTACC AATTTGGGTG GTCACCTAAC
TTTCCAACAT GCAAAGGACA AGTACGATCA TGTGGTCCAC CTCCTCAACT CTCCAATGGT
GAAGTTAAGG AGATAAGAAA AGAGGAATAT GGACACAATG AAGTAGTGGA ATATGATTGC
AATCCTAATT TTATAATAAA CGGGCCTAAG AAAATACAAT GTGTGGATGG AGAATGGACA
ACTTTACCCA CTTGTGTTGA ACAAGTGAAA ACATGTGGAT ACATACCTGA ACTCGAGTAC
GGTTATGTTC AGCCGTCTGT CCCTCCCTAT CAACATGGAG TTTCAGTCGA GGTGAATTGC
AGAAATGAAT ATGCAATGAT TGGAAATAAC ATGATTACCT GTATTAATGG AATATGGACA
GAGCTTCCTA TGTGTGTTGC AACACACCAA CTTAAGAGGT GCAAAATAGC AGGAGTTAAT
ATAAAAACAT TACTCAAGCT ATCTGGGAAA GAATTTAATC ATAATTCTAG AATACGTTAC
AGATGTTCAG ACATCTTCAG ATACAGGCAC TCAGTCTGTA TAAACGGGAA ATGGAATCCT
GAAGTAGACT GCACAGAAAA AAGGGAACAA TTCTGCCCAC CGCCACCTCA GATACCTAAT
GCTCAGAATA TGACAACCAC AGTGAATTAT CAGGATGGAG AAAAAGTAGC TGTTCTCTGT
AAAGAAAACT ATCTACTTCC AGAAGCAAAA GAAATTGTAT GTAAAGATGG ACGATGGCAA
TCATTACCAC GCTGTGTTGA GTCTACTGCA TATTGTGGGC CCCCTCCATC TATTAACAAT
GGAGATACCA CCTCATTCCC ATTATCAGTA TATCCTCCAG GGTCAACAGT GACGTACCGT
TGCCAGTCCT TCTATAAACT CCAGGGCTCT GTAACTGTAA CATGCAGAAA TAAACAGTGG
TCAGAACCAC CAAGATGCCT AGATCCATGT GTGGTATCTG AAGAAAACAT GAACAAAAAT
AACATACAGT TAAAATGGAG AAACGATGGA AAACTCTATG CAAAAACAGG GGATGCTGTT
GAATTCCAGT GTAAATTCCC ACATAAAGCG ATGATATCAT CACCACCATT TCGAGCAATC
TGTCAGGAAG GGAAATTTGA ATATCCTATA TGTGAATGA
The stop codons will be deleted if pcDNA3.1-C-(k)DYK vector is selected.
RefSeqXP_011508322.1
CDS12..1730
Misc Feature(1)279..440(+)
Misc Feature(2)306..365(+)
Misc Feature(3)459..626(+)
Misc Feature(4)489..548(+)
Misc Feature(5)642..809(+)
Misc Feature(6)672..734(+)
Misc Feature(7)825..989(+)
Misc Feature(8)855..914(+)
Misc Feature(9)1185..1349(+)
Misc Feature(10)1215..1274(+)
Misc Feature(11)1365..1529(+)
Misc Feature(12)1395..1457(+)
Translation
Position Chain Variation Link
4 4 a, g dbSNP:749966350
14 14 c, g dbSNP:566877684
30 30 a, c dbSNP:538169495
50 50 c, t dbSNP:754165438
69 69 g, t dbSNP:556406348
71 71 g, t dbSNP:115429171
79 79 c, g dbSNP:780291353
80 80 -, a dbSNP:764056849
82 82 a, c, t dbSNP:377563612
91 91 a, c dbSNP:536757077
104 104 a, c dbSNP:778970060
107 107 a, c dbSNP:371063140
110 110 a, t dbSNP:201612591
125 125 c, t dbSNP:555132638
126 126 -, gaa dbSNP:753711155
131 131 a, t dbSNP:776372315
133 133 a, g dbSNP:745812033
140 140 a, c, g dbSNP:200176406
141 141 c, g dbSNP:775126272
142 142 c, g dbSNP:762367817
150 150 c, t dbSNP:768399259
156 156 c, t dbSNP:12097550
158 158 c, t dbSNP:761513666
160 160 -, cag dbSNP:761721379
162 162 -, tt dbSNP:764958024
165 165 g, t dbSNP:199913139
166 166 a, t dbSNP:750756941
168 168 a, c, g dbSNP:761319757
174 174 c, t dbSNP:753989465
198 198 a, c, g dbSNP:370641856
214 214 c, t dbSNP:779001368
215 215 a, c dbSNP:752894097
225 225 c, g, t dbSNP:763857612
226 226 a, g, t dbSNP:375843181
233 233 a, g dbSNP:143503904
235 235 a, g dbSNP:368326752
237 237 a, g dbSNP:768077119
239 239 -, aga dbSNP:750169252
239 239 a, c dbSNP:773840564
246 246 a, g dbSNP:761567010
252 252 c, t dbSNP:146025130
253 253 a, c dbSNP:141256552
257 257 a, g dbSNP:112201342
262 262 c, t dbSNP:544857720
263 263 a, g dbSNP:7532068
273 273 a, g dbSNP:372885376
276 276 a, g dbSNP:190122254
278 278 g, t dbSNP:775616599
296 296 -, a dbSNP:748590126
303 303 g, t dbSNP:762992026
305 305 c, t dbSNP:764351908
315 315 c, t dbSNP:751805375
322 322 a, g dbSNP:147278469
330 330 c, t dbSNP:757464725
332 332 c, t dbSNP:766096486
334 334 c, g, t dbSNP:318240754
342 342 g, t dbSNP:753650925
346 346 c, t dbSNP:754934306
347 347 c, t dbSNP:536828292
349 349 c, t dbSNP:140691305
350 350 a, c dbSNP:61745675
352 352 a, c dbSNP:777378052
363 363 -, a dbSNP:756576112
369 369 a, g dbSNP:375328527
377 377 a, c, g dbSNP:770559120
381 381 -, c dbSNP:778029757
387 387 a, g dbSNP:746240586
390 390 a, g dbSNP:770245831
395 395 a, c dbSNP:775956342
396 396 a, c dbSNP:368988109
399 399 a, g dbSNP:764194328
403 403 c, t dbSNP:774353375
404 404 a, g, t dbSNP:147791058
405 405 c, t dbSNP:141053543
406 406 c, g, t dbSNP:754791022
410 410 a, g dbSNP:752687157
414 414 c, t dbSNP:758371568
415 415 a, g dbSNP:777447274
417 417 a, g dbSNP:746505923
418 418 g, t dbSNP:756898801
424 424 c, t dbSNP:780891284
426 426 a, t dbSNP:746274023
427 427 -, ctc dbSNP:757134794
428 428 c, t dbSNP:371596551
434 434 c, t dbSNP:372645937
435 435 a, g dbSNP:749821596
436 436 a, c, t dbSNP:140788459
439 439 g, t dbSNP:761951909
445 445 c, t dbSNP:772242835
447 447 a, c dbSNP:138529008
449 449 c, t dbSNP:140215003
451 451 a, g dbSNP:201787238
452 452 a, t dbSNP:181511327
454 454 a, g dbSNP:57960694
455 455 a, g dbSNP:575296882
456 456 g, t dbSNP:142998381
457 457 a, g dbSNP:761584967
459 459 c, t dbSNP:373071474
460 460 g, t dbSNP:749849330
481 481 a, c dbSNP:774909537
485 485 c, t dbSNP:139260377
495 495 c, g dbSNP:530388845
499 499 -, a, aa dbSNP:565457964
506 506 a, g dbSNP:77344042
510 510 a, g dbSNP:755352455
511 511 a, g dbSNP:779082409
525 525 c, g dbSNP:376292941
527 527 c, t dbSNP:34533956
528 528 a, g dbSNP:201073457
530 530 a, g dbSNP:144682444
542 542 c, t dbSNP:559593134
547 547 -, a dbSNP:746586384
547 547 a, g dbSNP:146658983
553 553 -, atctt dbSNP:776152799
553 553 a, g dbSNP:200427185
556 556 a, t dbSNP:746026492
558 558 a, g, t dbSNP:768499626
560 560 -, aa dbSNP:761664529
568 568 a, g dbSNP:773973110
569 569 a, t dbSNP:761827680
573 573 a, g dbSNP:767330423
577 577 a, c dbSNP:772849641
578 578 a, g dbSNP:760167433
583 583 a, t dbSNP:765820738
584 584 a, g dbSNP:753494719
593 593 a, c dbSNP:754586890
594 594 a, t dbSNP:765656585
596 596 g, t dbSNP:151134004
602 602 a, g dbSNP:758984179
603 603 a, t dbSNP:318240755
604 604 -, a dbSNP:765183774
611 611 a, c dbSNP:778137947
614 614 c, t dbSNP:138105988
619 619 a, c dbSNP:757424508
627 627 g, t dbSNP:781352172
628 628 c, g dbSNP:749471589
636 636 c, t dbSNP:771772296
637 637 a, g dbSNP:777505173
642 642 c, t dbSNP:41299613
643 643 a, g dbSNP:770833814
644 644 c, t dbSNP:776160345
648 648 c, t dbSNP:758964255
652 652 c, g dbSNP:369378973
663 663 c, t dbSNP:368406112
665 665 c, t dbSNP:775016574
666 666 a, t dbSNP:138834145
667 667 a, g, t dbSNP:147488267
668 668 c, t dbSNP:762454161
669 669 a, g dbSNP:768102677
671 671 a, t dbSNP:750591824
680 680 c, g dbSNP:756165621
685 685 c, t dbSNP:780116839
689 689 a, c dbSNP:373158868
697 697 -, a dbSNP:766749924
698 698 -, a dbSNP:368209619
698 698 a, c dbSNP:755180330
701 701 c, g, t dbSNP:777594999
703 703 c, g dbSNP:377160543
710 710 a, t dbSNP:781094025
716 716 a, g dbSNP:745760191
720 720 a, g dbSNP:755972876
731 731 a, c dbSNP:201267612
736 736 c, t dbSNP:762532931
737 737 c, t dbSNP:111360300
738 738 a, g dbSNP:768396961
748 748 c, t dbSNP:774892413
752 752 c, t dbSNP:41306229
753 753 a, g, t dbSNP:201808624
759 759 a, g dbSNP:761208050
760 760 a, c dbSNP:766392891
762 762 a, t dbSNP:753934056
770 770 a, g dbSNP:377449701
771 771 c, t dbSNP:755233985
776 776 a, g dbSNP:765442245
779 779 g, t dbSNP:140035708
780 780 a, g dbSNP:201472916
787 787 a, g dbSNP:374714775
788 788 g, t dbSNP:200899274
789 789 a, g dbSNP:780896136
790 790 a, c dbSNP:745822899
791 791 a, g dbSNP:370378714
793 793 c, t dbSNP:779477682
799 799 c, t dbSNP:748797364
824 824 -, at dbSNP:112327038
824 824 a, t dbSNP:376176542
825 825 c, t dbSNP:773490759
826 826 a, g dbSNP:747395792
829 829 a, g dbSNP:771400518
837 837 a, c dbSNP:777208363
839 839 a, t dbSNP:759969004
843 843 c, t dbSNP:769891523
845 845 c, t dbSNP:775498155
846 846 a, g dbSNP:199531514
849 849 a, t dbSNP:318240756
850 850 a, g dbSNP:764342851
851 851 c, t dbSNP:367607547
852 852 a, g dbSNP:139017763
855 855 a, t dbSNP:143240067
865 865 c, t dbSNP:753861647
866 866 a, c, g dbSNP:754917131
869 869 c, t dbSNP:752225304
881 881 c, t dbSNP:758055313
885 885 c, g dbSNP:777469135
886 886 a, g dbSNP:746586667
896 896 a, g dbSNP:771331309
899 899 c, t dbSNP:375290756
900 900 a, g, t dbSNP:201084185
903 903 a, g dbSNP:775584151
904 904 a, t dbSNP:763012335
912 912 a, g dbSNP:768815115
918 918 a, g dbSNP:774641645
931 931 a, t dbSNP:761903714
938 938 c, t dbSNP:766223951
943 943 c, t dbSNP:753667006
962 962 a, t dbSNP:759587394
965 965 a, g dbSNP:373625207
968 968 c, g dbSNP:765261884
974 974 a, g dbSNP:752315301
1005 1005 -, aag dbSNP:752782146
1010 1010 a, g dbSNP:763680401
1013 1013 a, c dbSNP:751010317
1026 1026 a, g dbSNP:756973491
1028 1028 g, t dbSNP:150007386
1031 1031 c, t dbSNP:533809706
1032 1032 a, g dbSNP:373395304
1040 1040 a, t dbSNP:750841234
1041 1041 c, t dbSNP:756481104
1043 1043 a, g dbSNP:369790664
1049 1049 a, g dbSNP:555221057
1051 1051 g, t dbSNP:201472083
1061 1061 a, g dbSNP:567158878
1065 1065 a, t dbSNP:748173075
1070 1070 c, t dbSNP:372608579
1080 1080 a, g dbSNP:370149020
1086 1086 c, t dbSNP:747163679
1087 1087 a, g dbSNP:35662416
1103 1103 c, t dbSNP:775374969
1110 1110 a, c dbSNP:762996619
1112 1112 a, t dbSNP:763907002
1116 1116 a, c dbSNP:773975353
1118 1118 a, g dbSNP:376503032
1120 1120 a, c dbSNP:766952894
1126 1126 c, t dbSNP:750077898
1136 1136 c, t dbSNP:556270179
1137 1137 c, g dbSNP:748127696
1138 1138 a, g dbSNP:376742710
1152 1152 a, g dbSNP:755579894
1155 1155 c, g dbSNP:111327589
1156 1156 a, t dbSNP:748631825
1157 1157 a, g dbSNP:779126931
1160 1160 c, t dbSNP:544997795
1161 1161 c, t dbSNP:777962172
1165 1165 c, g dbSNP:747255817
1175 1175 g, t dbSNP:141358257
1179 1179 c, t dbSNP:753176414
1182 1182 c, t dbSNP:541673379
1183 1183 c, t dbSNP:778046916
1185 1185 c, t dbSNP:751657767
1186 1186 g, t dbSNP:138239067
1192 1192 c, t dbSNP:201989784
1193 1193 a, g, t dbSNP:200148491
1197 1197 c, t dbSNP:778727030
1202 1202 g, t dbSNP:748135743
1205 1205 a, g dbSNP:771968391
1215 1215 c, t dbSNP:772780646
1222 1222 c, t dbSNP:201714199
1224 1224 a, g dbSNP:371188168
1230 1230 a, t dbSNP:776153246
1231 1231 a, c dbSNP:759190638
1233 1233 a, g dbSNP:765544022
1234 1234 a, t dbSNP:375120052
1244 1244 -, g dbSNP:771972507
1249 1249 a, g dbSNP:550955462
1271 1271 c, t dbSNP:764693671
1280 1280 -, ctat dbSNP:776040836
1284 1284 c, g dbSNP:751747329
1305 1305 a, g dbSNP:575322664
1307 1307 g, t dbSNP:370760497
1309 1309 c, t dbSNP:781262039
1310 1310 a, g dbSNP:750638931
1311 1311 c, t dbSNP:756308122
1312 1312 a, g dbSNP:202020361
1314 1314 a, g dbSNP:778616159
1319 1319 c, t dbSNP:747935430
1323 1323 c, t dbSNP:758392186
1324 1324 a, g dbSNP:776538115
1326 1326 c, t dbSNP:746882889
1328 1328 a, g, t dbSNP:201265664
1336 1336 c, t dbSNP:776160815
1338 1338 c, t dbSNP:745555026
1341 1341 c, t dbSNP:769456068
1342 1342 a, g dbSNP:776063846
1343 1343 c, t dbSNP:763395466
1346 1346 a, t dbSNP:764491329
1349 1349 c, t dbSNP:376673503
1350 1350 a, g, t dbSNP:370810049
1353 1353 a, t dbSNP:763928131
1354 1354 c, t dbSNP:751336918
1357 1357 a, c dbSNP:757207440
1358 1358 c, t dbSNP:781175814
1370 1370 a, g, t dbSNP:77159278
1374 1374 c, t dbSNP:368052499
1377 1377 c, g, t dbSNP:184883943
1378 1378 c, t dbSNP:779489184
1379 1379 a, g dbSNP:748535741
1380 1380 g, t dbSNP:745464729
1389 1389 a, g dbSNP:371283133
1393 1393 a, g dbSNP:550168649
1394 1394 a, c dbSNP:761047224
1397 1397 c, t dbSNP:565171231
1405 1405 c, t dbSNP:373865739
1409 1409 a, c dbSNP:368569601
1412 1412 a, g dbSNP:146399759
1416 1416 a, t dbSNP:765440033
1419 1419 -, t dbSNP:769671871
1419 1419 a, g dbSNP:751368164
1420 1420 g, t dbSNP:372401518
1424 1424 c, t dbSNP:761680547
1430 1430 a, g dbSNP:372074990
1431 1431 c, g dbSNP:750401965
1432 1432 a, g dbSNP:144438200
1433 1433 -, tcc dbSNP:773171763
1437 1437 a, g dbSNP:779757280
1444 1444 c, t dbSNP:150742682
1445 1445 a, c, g dbSNP:754737527
1449 1449 c, t dbSNP:747692331
1450 1450 a, g dbSNP:149905969
1453 1453 a, g dbSNP:571204851
1456 1456 a, g, t dbSNP:144490092
1457 1457 a, g dbSNP:771398135
1462 1462 a, t dbSNP:143038171
1466 1466 c, t dbSNP:776756790
1477 1477 c, g dbSNP:759597046
1488 1488 c, g dbSNP:769805832
1491 1491 a, g dbSNP:775784945
1507 1507 -, ag dbSNP:762909951
1507 1507 a, c dbSNP:763040757
1510 1510 c, g dbSNP:767362814
1516 1516 -, a dbSNP:766264429
1520 1520 a, c dbSNP:750159388
1523 1523 a, c dbSNP:760732365
1528 1528 a, g dbSNP:766407803
1530 1530 c, t dbSNP:753773255
1531 1531 -, t dbSNP:774231868
1533 1533 a, c, g dbSNP:200468491
1539 1539 c, t dbSNP:773124493
1542 1542 g, t dbSNP:760562488
1549 1549 c, g dbSNP:766211328
1561 1561 g, t dbSNP:141321678
1580 1580 a, c, g dbSNP:202093724
1581 1581 a, c, t dbSNP:35957013
1587 1587 c, t dbSNP:763638797
1595 1595 c, g dbSNP:751152463
1596 1596 a, g, t dbSNP:757619029
1598 1598 c, t dbSNP:369454163
1606 1606 g, t dbSNP:16840956
1609 1609 a, c dbSNP:780221023
1617 1617 a, g dbSNP:749321849
1621 1621 a, g dbSNP:768724676
1622 1622 c, g dbSNP:774720562
1623 1623 a, g dbSNP:748341345
1624 1624 a, g dbSNP:138797107
1629 1629 a, g dbSNP:540104721
1635 1635 g, t dbSNP:111989094
1642 1642 a, g dbSNP:372475730
1643 1643 c, t dbSNP:765084938
1648 1648 a, t dbSNP:775126222
1649 1649 c, t dbSNP:762380054
1660 1660 c, t dbSNP:534950713
1661 1661 a, g dbSNP:74323799
1664 1664 a, g dbSNP:761401350
1665 1665 a, t dbSNP:149614133
1667 1667 a, g dbSNP:142546471
1675 1675 c, t dbSNP:756709352
1683 1683 c, t dbSNP:780410370
1684 1684 c, g dbSNP:143599784
1691 1691 a, c dbSNP:541614172
1698 1698 a, g dbSNP:779087611
1716 1716 a, c, t dbSNP:748430882
1717 1717 c, t dbSNP:781203577
1718 1718 c, t dbSNP:745639180
1721 1721 a, g dbSNP:769572476
1724 1724 a, t dbSNP:143140599
1728 1728 c, t dbSNP:762904582
1729 1729 a, g dbSNP:369410913
1730 1730 a, t dbSNP:773828786
1733 1733 c, g dbSNP:761491916
1737 1737 c, t dbSNP:767151038
1740 1740 a, g dbSNP:750843342
1750 1750 a, c dbSNP:760954453
1769 1769 c, t dbSNP:747312519
1770 1770 a, g dbSNP:199554431
1771 1771 a, t dbSNP:369204442
1772 1772 c, t dbSNP:371795291
1777 1777 a, c dbSNP:779177613
1778 1778 a, g, t dbSNP:752824001
1779 1779 a, g dbSNP:769122811
1780 1780 a, t dbSNP:747186769
1782 1782 a, g dbSNP:769505570
1789 1789 a, g dbSNP:545416040
1856 1856 c, g dbSNP:563764666
1953 1953 a, g dbSNP:559647040
2026 2026 g, t dbSNP:776710591
2127 2127 c, g dbSNP:115744316
2137 2137 a, t dbSNP:769938869
2152 2152 a, g dbSNP:148256048
2166 2166 c, t dbSNP:562239793
2172 2172 c, t dbSNP:542330909
2232 2232 c, t dbSNP:561492578
2302 2302 c, t dbSNP:529500424
2313 2313 a, t dbSNP:745408180
2335 2335 c, t dbSNP:541811310
2349 2349 a, g dbSNP:550863021
2431 2431 c, t dbSNP:773449247
2471 2471 g, t dbSNP:117389812
2532 2532 g, t dbSNP:10922153
2536 2536 a, g dbSNP:551890459
2549 2549 c, t dbSNP:575601631
2579 2579 a, g dbSNP:775034377
2582 2582 a, c dbSNP:566913870
2596 2596 a, g dbSNP:534182452
2693 2693 a, t dbSNP:57315298
2699 2699 a, t dbSNP:115075908
2723 2723 g, t dbSNP:568222338

Target ORF information:

RefSeq Version XM_011510020
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens complement factor H-related 5 (CFHR5), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1-C-(k)DYK
XM_011510020

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
ATGGTGAAGC CTTTGAGACA GAAGAGAAAC CAGGAGAATG TGGTGTTCCA TAGACCATGT 
GAAGCAGGAA CACTTTGTGA TTTTCCAAAA ATACACCATG GATTTCTGTA TGATGAAGAA
GATTATAACC CTTTTTCCCA AGTTCCTACA GGGGAAGTTT TCTATTACTC CTGTGAATAT
AATTTTGTGT CTCCTTCAAA ATCCTTTTGG ACTCGCATAA CATGCACAGA AGAAGGATGG
TCACCAACAC CGAAGTGTCT CAGAATGTGT TCCTTTCCTT TTGTGAAAAA TGGTCATTCT
GAATCTTCAG GACTAATACA TCTGGAAGGT GATACTGTAC AAATTATTTG CAACACAGGA
TACAGCCTTC AAAACAATGA GAAAAACATT TCGTGTGTAG AACGGGGCTG GTCCACTCCT
CCCATATGCA GCTTCACTAA AGGAGAATGT CATGTTCCAA TTTTAGAAGC CAATGTAGAT
GCTCAGCCAA AAAAAGAAAG CTACAAAGTT GGAGACGTGT TGAAATTCTC CTGCAGAAAA
AATCTTATAA GAGTTGGATC AGACTCAGTT CAATGTTACC AATTTGGGTG GTCACCTAAC
TTTCCAACAT GCAAAGGACA AGTACGATCA TGTGGTCCAC CTCCTCAACT CTCCAATGGT
GAAGTTAAGG AGATAAGAAA AGAGGAATAT GGACACAATG AAGTAGTGGA ATATGATTGC
AATCCTAATT TTATAATAAA CGGGCCTAAG AAAATACAAT GTGTGGATGG AGAATGGACA
ACTTTACCCA CTTGTGTTGA ACAAGTGAAA ACATGTGGAT ACATACCTGA ACTCGAGTAC
GGTTATGTTC AGCCGTCTGT CCCTCCCTAT CAACATGGAG TTTCAGTCGA GGTGAATTGC
AGAAATGAAT ATGCAATGAT TGGAAATAAC ATGATTACCT GTATTAATGG AATATGGACA
GAGCTTCCTA TGTGTGTTGC AACACACCAA CTTAAGAGGT GCAAAATAGC AGGAGTTAAT
ATAAAAACAT TACTCAAGCT ATCTGGGAAA GAATTTAATC ATAATTCTAG AATACGTTAC
AGATGTTCAG ACATCTTCAG ATACAGGCAC TCAGTCTGTA TAAACGGGAA ATGGAATCCT
GAAGTAGACT GCACAGAAAA AAGGGAACAA TTCTGCCCAC CGCCACCTCA GATACCTAAT
GCTCAGAATA TGACAACCAC AGTGAATTAT CAGGATGGAG AAAAAGTAGC TGTTCTCTGT
AAAGAAAACT ATCTACTTCC AGAAGCAAAA GAAATTGTAT GTAAAGATGG ACGATGGCAA
TCATTACCAC GCTGTGTTGA GTCTACTGCA TATTGTGGGC CCCCTCCATC TATTAACAAT
GGAGATACCA CCTCATTCCC ATTATCAGTA TATCCTCCAG GGTCAACAGT GACGTACCGT
TGCCAGTCCT TCTATAAACT CCAGGGCTCT GTAACTGTAA CATGCAGAAA TAAACAGTGG
TCAGAACCAC CAAGATGCCT AGATCCATGT GTGGTATCTG AAGAAAACAT GAACAAAAAT
AACATACAGT TAAAATGGAG AAACGATGGA AAACTCTATG CAAAAACAGG GGATGCTGTT
GAATTCCAGT GTAAATTCCC ACATAAAGCG ATGATATCAT CACCACCATT TCGAGCAATC
TGTCAGGAAG GGAAATTTGA ATATCCTATA TGTGAATGA

The stop codons will be deleted if pcDNA3.1-C-(k)DYK vector is selected.


CloneID OHu22543D
Sequence Information ORF Nucleotide Sequence (Length: 1710bp)
Protein sequence
SNP
Vector pcDNA3.1-C-(k)DYK or customized vector
Clone information Clone Map
Tag on pcDNA3.1-C-(k)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product complement factor H-related protein 5 precursor
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA638244.1, BC111773.1, BG568555.1 and AF295327.1. This sequence is a reference standard in the RefSeqGene project. On Jan 11, 2008 this sequence version replaced gi:142362265. Summary: This gene is a member of a small complement factor H (CFH) gene cluster on chromosome 1. Each member of this gene family contains multiple short consensus repeats (SCRs) typical of regulators of complement activation. The protein encoded by this gene has nine SCRs with the first two repeats having heparin binding properties, a region within repeats 5-7 having heparin binding and C reactive protein binding properties, and the C-terminal repeats being similar to a complement component 3 b (C3b) binding domain. This protein co-localizes with C3, binds C3b in a dose-dependent manner, and is recruited to tissues damaged by C-reactive protein. Allelic variations in this gene have been associated, but not causally linked, with two different forms of kidney disease: membranoproliferative glomerulonephritis type II (MPGNII) and hemolytic uraemic syndrome (HUS). [provided by RefSeq, Jan 2010]. Sequence Note: An in-frame AUG is located 24 codons upstream of the annotated translation start site but is not being annotated as a start site since it is not conserved and is in a weak Kozak sequence context. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##RefSeq-Attributes-START## CDS uses downstream in-frame AUG :: upstream AUG and CDS extension is not conserved ##RefSeq-Attributes-END## ##Evidence-Data-START## Transcript exon combination :: AF295327.1, BC111773.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145122, SAMEA2155590 [ECO:0000348] ##Evidence-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
ATGTTGCTCT TATTCAGTGT AATCCTAATC TCATGGGTAT CCACTGTTGG GGGAGAAGGA 
ACACTTTGTG ATTTTCCAAA AATACACCAT GGATTTCTGT ATGATGAAGA AGATTATAAC
CCTTTTTCCC AAGTTCCTAC AGGGGAAGTT TTCTATTACT CCTGTGAATA TAATTTTGTG
TCTCCTTCAA AATCCTTTTG GACTCGCATA ACATGCACAG AAGAAGGATG GTCACCAACA
CCGAAGTGTC TCAGAATGTG TTCCTTTCCT TTTGTGAAAA ATGGTCATTC TGAATCTTCA
GGACTAATAC ATCTGGAAGG TGATACTGTA CAAATTATTT GCAACACAGG ATACAGCCTT
CAAAACAATG AGAAAAACAT TTCGTGTGTA GAACGGGGCT GGTCCACTCC TCCCATATGC
AGCTTCACTA AAGGAGAATG TCATGTTCCA ATTTTAGAAG CCAATGTAGA TGCTCAGCCA
AAAAAAGAAA GCTACAAAGT TGGAGACGTG TTGAAATTCT CCTGCAGAAA AAATCTTATA
AGAGTTGGAT CAGACTCAGT TCAATGTTAC CAATTTGGGT GGTCACCTAA CTTTCCAACA
TGCAAAGGAC AAGTACGATC ATGTGGTCCA CCTCCTCAAC TCTCCAATGG TGAAGTTAAG
GAGATAAGAA AAGAGGAATA TGGACACAAT GAAGTAGTGG AATATGATTG CAATCCTAAT
TTTATAATAA ACGGGCCTAA GAAAATACAA TGTGTGGATG GAGAATGGAC AACTTTACCC
ACTTGTGTTG AACAAGTGAA AACATGTGGA TACATACCTG AACTCGAGTA CGGTTATGTT
CAGCCGTCTG TCCCTCCCTA TCAACATGGA GTTTCAGTCG AGGTGAATTG CAGAAATGAA
TATGCAATGA TTGGAAATAA CATGATTACC TGTATTAATG GAATATGGAC AGAGCTTCCT
ATGTGTGTTG CAACACACCA ACTTAAGAGG TGCAAAATAG CAGGAGTTAA TATAAAAACA
TTACTCAAGC TATCTGGGAA AGAATTTAAT CATAATTCTA GAATACGTTA CAGATGTTCA
GACATCTTCA GATACAGGCA CTCAGTCTGT ATAAACGGGA AATGGAATCC TGAAGTAGAC
TGCACAGAAA AAAGGGAACA ATTCTGCCCA CCGCCACCTC AGATACCTAA TGCTCAGAAT
ATGACAACCA CAGTGAATTA TCAGGATGGA GAAAAAGTAG CTGTTCTCTG TAAAGAAAAC
TATCTACTTC CAGAAGCAAA AGAAATTGTA TGTAAAGATG GACGATGGCA ATCATTACCA
CGCTGTGTTG AGTCTACTGC ATATTGTGGG CCCCCTCCAT CTATTAACAA TGGAGATACC
ACCTCATTCC CATTATCAGT ATATCCTCCA GGGTCAACAG TGACGTACCG TTGCCAGTCC
TTCTATAAAC TCCAGGGCTC TGTAACTGTA ACATGCAGAA ATAAACAGTG GTCAGAACCA
CCAAGATGCC TAGATCCATG TGTGGTATCT GAAGAAAACA TGAACAAAAA TAACATACAG
TTAAAATGGA GAAACGATGG AAAACTCTAT GCAAAAACAG GGGATGCTGT TGAATTCCAG
TGTAAATTCC CACATAAAGC GATGATATCA TCACCACCAT TTCGAGCAAT CTGTCAGGAA
GGGAAATTTG AATATCCTAT ATGTGAATGA
The stop codons will be deleted if pcDNA3.1-C-(k)DYK vector is selected.
RefSeqNP_110414.1
CDS129..1838
Misc Feature(1)48..50(+)
Misc Feature(2)387..548(+)
Misc Feature(3)414..473(+)
Misc Feature(4)567..734(+)
Misc Feature(5)597..656(+)
Misc Feature(6)750..917(+)
Misc Feature(7)780..842(+)
Misc Feature(8)933..1097(+)
Misc Feature(9)963..1022(+)
Misc Feature(10)1293..1457(+)
Misc Feature(11)1323..1382(+)
Misc Feature(12)1473..1637(+)
Misc Feature(13)1503..1565(+)
Exon (1)1..186
Gene:CFHR5
Gene Synonym:
Exon (2)187..381
Gene:CFHR5
Gene Synonym:
Exon (3)382..558
Gene:CFHR5
Gene Synonym:
Exon (4)559..735
Gene:CFHR5
Gene Synonym:
Exon (5)736..918
Gene:CFHR5
Gene Synonym:
Exon (6)919..1098
Gene:CFHR5
Gene Synonym:
Exon (7)1099..1275
Gene:CFHR5
Gene Synonym:
Exon (8)1276..1458
Gene:CFHR5
Gene Synonym:
Exon (9)1459..1641
Gene:CFHR5
Gene Synonym:
Exon (10)1642..2829
Gene:CFHR5
Gene Synonym:
Translation
Position Chain Variation Link
7 7 c, t dbSNP:774350390
14 14 a, c dbSNP:761699716
16 16 c, t dbSNP:530423106
21 21 a, g dbSNP:200054371
26 26 c, t dbSNP:750391954
43 43 a, g dbSNP:760487448
44 44 a, c dbSNP:765914581
45 45 g, t dbSNP:753285642
49 49 a, g dbSNP:754681144
51 51 -, tg dbSNP:768496253
52 52 -, tg dbSNP:551454946
57 57 a, g dbSNP:778532188
61 61 a, g dbSNP:753099679
67 67 a, g dbSNP:758768294
71 71 a, c dbSNP:777951547
83 83 a, c dbSNP:747585174
86 86 a, t dbSNP:771277790
107 107 c, t dbSNP:548874653
108 108 a, g dbSNP:745932271
109 109 c, t dbSNP:9427662
112 112 a, g dbSNP:370203146
120 120 -, t dbSNP:781759572
122 122 -, tt dbSNP:748586869
124 124 -, ca dbSNP:770049666
124 124 a, c, g dbSNP:112503996
127 127 g, t dbSNP:531047040
128 128 -, ca dbSNP:773566789
144 144 a, g dbSNP:771928486
146 146 c, t dbSNP:772813940
152 152 c, g dbSNP:760672492
158 158 c, t dbSNP:766289860
160 160 c, g dbSNP:776188297
175 175 c, t dbSNP:759014482
176 176 -, g dbSNP:771671663
178 178 a, c, g dbSNP:764919855
180 180 a, g dbSNP:757949121
181 181 a, g dbSNP:764524706
185 185 a, c dbSNP:751816312
187 187 c, g dbSNP:780291353
188 188 -, a dbSNP:764056849
190 190 a, c, t dbSNP:377563612
199 199 a, c dbSNP:536757077
212 212 a, c dbSNP:778970060
215 215 a, c dbSNP:371063140
218 218 a, t dbSNP:201612591
233 233 c, t dbSNP:555132638
234 234 -, gaa dbSNP:753711155
239 239 a, t dbSNP:776372315
241 241 a, g dbSNP:745812033
248 248 a, c, g dbSNP:200176406
249 249 c, g dbSNP:775126272
250 250 c, g dbSNP:762367817
258 258 c, t dbSNP:768399259
264 264 c, t dbSNP:12097550
266 266 c, t dbSNP:761513666
268 268 -, cag dbSNP:761721379
270 270 -, tt dbSNP:764958024
273 273 g, t dbSNP:199913139
274 274 a, t dbSNP:750756941
276 276 a, c, g dbSNP:761319757
282 282 c, t dbSNP:753989465
306 306 a, c, g dbSNP:370641856
322 322 c, t dbSNP:779001368
323 323 a, c dbSNP:752894097
333 333 c, g, t dbSNP:763857612
334 334 a, g, t dbSNP:375843181
341 341 a, g dbSNP:143503904
343 343 a, g dbSNP:368326752
345 345 a, g dbSNP:768077119
347 347 -, aga dbSNP:750169252
347 347 a, c dbSNP:773840564
354 354 a, g dbSNP:761567010
360 360 c, t dbSNP:146025130
361 361 a, c dbSNP:141256552
365 365 a, g dbSNP:112201342
370 370 c, t dbSNP:544857720
371 371 a, g dbSNP:7532068
381 381 a, g dbSNP:372885376
384 384 a, g dbSNP:190122254
386 386 g, t dbSNP:775616599
404 404 -, a dbSNP:748590126
411 411 g, t dbSNP:762992026
413 413 c, t dbSNP:764351908
423 423 c, t dbSNP:751805375
430 430 a, g dbSNP:147278469
438 438 c, t dbSNP:757464725
440 440 c, t dbSNP:766096486
442 442 c, g, t dbSNP:318240754
450 450 g, t dbSNP:753650925
454 454 c, t dbSNP:754934306
455 455 c, t dbSNP:536828292
457 457 c, t dbSNP:140691305
458 458 a, c dbSNP:61745675
460 460 a, c dbSNP:777378052
471 471 -, a dbSNP:756576112
477 477 a, g dbSNP:375328527
485 485 a, c, g dbSNP:770559120
489 489 -, c dbSNP:778029757
495 495 a, g dbSNP:746240586
498 498 a, g dbSNP:770245831
503 503 a, c dbSNP:775956342
504 504 a, c dbSNP:368988109
507 507 a, g dbSNP:764194328
511 511 c, t dbSNP:774353375
512 512 a, g, t dbSNP:147791058
513 513 c, t dbSNP:141053543
514 514 c, g, t dbSNP:754791022
518 518 a, g dbSNP:752687157
522 522 c, t dbSNP:758371568
523 523 a, g dbSNP:777447274
525 525 a, g dbSNP:746505923
526 526 g, t dbSNP:756898801
532 532 c, t dbSNP:780891284
534 534 a, t dbSNP:746274023
535 535 -, ctc dbSNP:757134794
536 536 c, t dbSNP:371596551
542 542 c, t dbSNP:372645937
543 543 a, g dbSNP:749821596
544 544 a, c, t dbSNP:140788459
547 547 g, t dbSNP:761951909
553 553 c, t dbSNP:772242835
555 555 a, c dbSNP:138529008
557 557 c, t dbSNP:140215003
559 559 a, g dbSNP:201787238
560 560 a, t dbSNP:181511327
562 562 a, g dbSNP:57960694
563 563 a, g dbSNP:575296882
564 564 g, t dbSNP:142998381
565 565 a, g dbSNP:761584967
567 567 c, t dbSNP:373071474
568 568 g, t dbSNP:749849330
589 589 a, c dbSNP:774909537
593 593 c, t dbSNP:139260377
603 603 c, g dbSNP:530388845
607 607 -, a, aa dbSNP:565457964
614 614 a, g dbSNP:77344042
618 618 a, g dbSNP:755352455
619 619 a, g dbSNP:779082409
633 633 c, g dbSNP:376292941
635 635 c, t dbSNP:34533956
636 636 a, g dbSNP:201073457
638 638 a, g dbSNP:144682444
650 650 c, t dbSNP:559593134
655 655 -, a dbSNP:746586384
655 655 a, g dbSNP:146658983
661 661 -, atctt dbSNP:776152799
661 661 a, g dbSNP:200427185
664 664 a, t dbSNP:746026492
666 666 a, g, t dbSNP:768499626
668 668 -, aa dbSNP:761664529
676 676 a, g dbSNP:773973110
677 677 a, t dbSNP:761827680
681 681 a, g dbSNP:767330423
685 685 a, c dbSNP:772849641
686 686 a, g dbSNP:760167433
691 691 a, t dbSNP:765820738
692 692 a, g dbSNP:753494719
701 701 a, c dbSNP:754586890
702 702 a, t dbSNP:765656585
704 704 g, t dbSNP:151134004
710 710 a, g dbSNP:758984179
711 711 a, t dbSNP:318240755
712 712 -, a dbSNP:765183774
719 719 a, c dbSNP:778137947
722 722 c, t dbSNP:138105988
727 727 a, c dbSNP:757424508
735 735 g, t dbSNP:781352172
736 736 c, g dbSNP:749471589
744 744 c, t dbSNP:771772296
745 745 a, g dbSNP:777505173
750 750 c, t dbSNP:41299613
751 751 a, g dbSNP:770833814
752 752 c, t dbSNP:776160345
756 756 c, t dbSNP:758964255
760 760 c, g dbSNP:369378973
771 771 c, t dbSNP:368406112
773 773 c, t dbSNP:775016574
774 774 a, t dbSNP:138834145
775 775 a, g, t dbSNP:147488267
776 776 c, t dbSNP:762454161
777 777 a, g dbSNP:768102677
779 779 a, t dbSNP:750591824
788 788 c, g dbSNP:756165621
793 793 c, t dbSNP:780116839
797 797 a, c dbSNP:373158868
805 805 -, a dbSNP:766749924
806 806 -, a dbSNP:368209619
806 806 a, c dbSNP:755180330
809 809 c, g, t dbSNP:777594999
811 811 c, g dbSNP:377160543
818 818 a, t dbSNP:781094025
824 824 a, g dbSNP:745760191
828 828 a, g dbSNP:755972876
839 839 a, c dbSNP:201267612
844 844 c, t dbSNP:762532931
845 845 c, t dbSNP:111360300
846 846 a, g dbSNP:768396961
856 856 c, t dbSNP:774892413
860 860 c, t dbSNP:41306229
861 861 a, g, t dbSNP:201808624
867 867 a, g dbSNP:761208050
868 868 a, c dbSNP:766392891
870 870 a, t dbSNP:753934056
878 878 a, g dbSNP:377449701
879 879 c, t dbSNP:755233985
884 884 a, g dbSNP:765442245
887 887 g, t dbSNP:140035708
888 888 a, g dbSNP:201472916
895 895 a, g dbSNP:374714775
896 896 g, t dbSNP:200899274
897 897 a, g dbSNP:780896136
898 898 a, c dbSNP:745822899
899 899 a, g dbSNP:370378714
901 901 c, t dbSNP:779477682
907 907 c, t dbSNP:748797364
932 932 -, at dbSNP:112327038
932 932 a, t dbSNP:376176542
933 933 c, t dbSNP:773490759
934 934 a, g dbSNP:747395792
937 937 a, g dbSNP:771400518
945 945 a, c dbSNP:777208363
947 947 a, t dbSNP:759969004
951 951 c, t dbSNP:769891523
953 953 c, t dbSNP:775498155
954 954 a, g dbSNP:199531514
957 957 a, t dbSNP:318240756
958 958 a, g dbSNP:764342851
959 959 c, t dbSNP:367607547
960 960 a, g dbSNP:139017763
963 963 a, t dbSNP:143240067
973 973 c, t dbSNP:753861647
974 974 a, c, g dbSNP:754917131
977 977 c, t dbSNP:752225304
989 989 c, t dbSNP:758055313
993 993 c, g dbSNP:777469135
994 994 a, g dbSNP:746586667
1004 1004 a, g dbSNP:771331309
1007 1007 c, t dbSNP:375290756
1008 1008 a, g, t dbSNP:201084185
1011 1011 a, g dbSNP:775584151
1012 1012 a, t dbSNP:763012335
1020 1020 a, g dbSNP:768815115
1026 1026 a, g dbSNP:774641645
1039 1039 a, t dbSNP:761903714
1046 1046 c, t dbSNP:766223951
1051 1051 c, t dbSNP:753667006
1070 1070 a, t dbSNP:759587394
1073 1073 a, g dbSNP:373625207
1076 1076 c, g dbSNP:765261884
1082 1082 a, g dbSNP:752315301
1113 1113 -, aag dbSNP:752782146
1118 1118 a, g dbSNP:763680401
1121 1121 a, c dbSNP:751010317
1134 1134 a, g dbSNP:756973491
1136 1136 g, t dbSNP:150007386
1139 1139 c, t dbSNP:533809706
1140 1140 a, g dbSNP:373395304
1148 1148 a, t dbSNP:750841234
1149 1149 c, t dbSNP:756481104
1151 1151 a, g dbSNP:369790664
1157 1157 a, g dbSNP:555221057
1159 1159 g, t dbSNP:201472083
1169 1169 a, g dbSNP:567158878
1173 1173 a, t dbSNP:748173075
1178 1178 c, t dbSNP:372608579
1188 1188 a, g dbSNP:370149020
1194 1194 c, t dbSNP:747163679
1195 1195 a, g dbSNP:35662416
1211 1211 c, t dbSNP:775374969
1218 1218 a, c dbSNP:762996619
1220 1220 a, t dbSNP:763907002
1224 1224 a, c dbSNP:773975353
1226 1226 a, g dbSNP:376503032
1228 1228 a, c dbSNP:766952894
1234 1234 c, t dbSNP:750077898
1244 1244 c, t dbSNP:556270179
1245 1245 c, g dbSNP:748127696
1246 1246 a, g dbSNP:376742710
1260 1260 a, g dbSNP:755579894
1263 1263 c, g dbSNP:111327589
1264 1264 a, t dbSNP:748631825
1265 1265 a, g dbSNP:779126931
1268 1268 c, t dbSNP:544997795
1269 1269 c, t dbSNP:777962172
1273 1273 c, g dbSNP:747255817
1283 1283 g, t dbSNP:141358257
1287 1287 c, t dbSNP:753176414
1290 1290 c, t dbSNP:541673379
1291 1291 c, t dbSNP:778046916
1293 1293 c, t dbSNP:751657767
1294 1294 g, t dbSNP:138239067
1300 1300 c, t dbSNP:201989784
1301 1301 a, g, t dbSNP:200148491
1305 1305 c, t dbSNP:778727030
1310 1310 g, t dbSNP:748135743
1313 1313 a, g dbSNP:771968391
1323 1323 c, t dbSNP:772780646
1330 1330 c, t dbSNP:201714199
1332 1332 a, g dbSNP:371188168
1338 1338 a, t dbSNP:776153246
1339 1339 a, c dbSNP:759190638
1341 1341 a, g dbSNP:765544022
1342 1342 a, t dbSNP:375120052
1352 1352 -, g dbSNP:771972507
1357 1357 a, g dbSNP:550955462
1379 1379 c, t dbSNP:764693671
1388 1388 -, ctat dbSNP:776040836
1392 1392 c, g dbSNP:751747329
1413 1413 a, g dbSNP:575322664
1415 1415 g, t dbSNP:370760497
1417 1417 c, t dbSNP:781262039
1418 1418 a, g dbSNP:750638931
1419 1419 c, t dbSNP:756308122
1420 1420 a, g dbSNP:202020361
1422 1422 a, g dbSNP:778616159
1427 1427 c, t dbSNP:747935430
1431 1431 c, t dbSNP:758392186
1432 1432 a, g dbSNP:776538115
1434 1434 c, t dbSNP:746882889
1436 1436 a, g, t dbSNP:201265664
1444 1444 c, t dbSNP:776160815
1446 1446 c, t dbSNP:745555026
1449 1449 c, t dbSNP:769456068
1450 1450 a, g dbSNP:776063846
1451 1451 c, t dbSNP:763395466
1454 1454 a, t dbSNP:764491329
1457 1457 c, t dbSNP:376673503
1458 1458 a, g, t dbSNP:370810049
1461 1461 a, t dbSNP:763928131
1462 1462 c, t dbSNP:751336918
1465 1465 a, c dbSNP:757207440
1466 1466 c, t dbSNP:781175814
1478 1478 a, g, t dbSNP:77159278
1482 1482 c, t dbSNP:368052499
1485 1485 c, g, t dbSNP:184883943
1486 1486 c, t dbSNP:779489184
1487 1487 a, g dbSNP:748535741
1488 1488 g, t dbSNP:745464729
1497 1497 a, g dbSNP:371283133
1501 1501 a, g dbSNP:550168649
1502 1502 a, c dbSNP:761047224
1505 1505 c, t dbSNP:565171231
1513 1513 c, t dbSNP:373865739
1517 1517 a, c dbSNP:368569601
1520 1520 a, g dbSNP:146399759
1524 1524 a, t dbSNP:765440033
1527 1527 -, t dbSNP:769671871
1527 1527 a, g dbSNP:751368164
1528 1528 g, t dbSNP:372401518
1532 1532 c, t dbSNP:761680547
1538 1538 a, g dbSNP:372074990
1539 1539 c, g dbSNP:750401965
1540 1540 a, g dbSNP:144438200
1541 1541 -, tcc dbSNP:773171763
1545 1545 a, g dbSNP:779757280
1552 1552 c, t dbSNP:150742682
1553 1553 a, c, g dbSNP:754737527
1557 1557 c, t dbSNP:747692331
1558 1558 a, g dbSNP:149905969
1561 1561 a, g dbSNP:571204851
1564 1564 a, g, t dbSNP:144490092
1565 1565 a, g dbSNP:771398135
1570 1570 a, t dbSNP:143038171
1574 1574 c, t dbSNP:776756790
1585 1585 c, g dbSNP:759597046
1596 1596 c, g dbSNP:769805832
1599 1599 a, g dbSNP:775784945
1615 1615 -, ag dbSNP:762909951
1615 1615 a, c dbSNP:763040757
1618 1618 c, g dbSNP:767362814
1624 1624 -, a dbSNP:766264429
1628 1628 a, c dbSNP:750159388
1631 1631 a, c dbSNP:760732365
1636 1636 a, g dbSNP:766407803
1638 1638 c, t dbSNP:753773255
1639 1639 -, t dbSNP:774231868
1641 1641 a, c, g dbSNP:200468491
1647 1647 c, t dbSNP:773124493
1650 1650 g, t dbSNP:760562488
1657 1657 c, g dbSNP:766211328
1669 1669 g, t dbSNP:141321678
1688 1688 a, c, g dbSNP:202093724
1689 1689 a, c, t dbSNP:35957013
1695 1695 c, t dbSNP:763638797
1703 1703 c, g dbSNP:751152463
1704 1704 a, g, t dbSNP:757619029
1706 1706 c, t dbSNP:369454163
1714 1714 g, t dbSNP:16840956
1717 1717 a, c dbSNP:780221023
1725 1725 a, g dbSNP:749321849
1729 1729 a, g dbSNP:768724676
1730 1730 c, g dbSNP:774720562
1731 1731 a, g dbSNP:748341345
1732 1732 a, g dbSNP:138797107
1737 1737 a, g dbSNP:540104721
1743 1743 g, t dbSNP:111989094
1750 1750 a, g dbSNP:372475730
1751 1751 c, t dbSNP:765084938
1756 1756 a, t dbSNP:775126222
1757 1757 c, t dbSNP:762380054
1768 1768 c, t dbSNP:534950713
1769 1769 a, g dbSNP:74323799
1772 1772 a, g dbSNP:761401350
1773 1773 a, t dbSNP:149614133
1775 1775 a, g dbSNP:142546471
1783 1783 c, t dbSNP:756709352
1791 1791 c, t dbSNP:780410370
1792 1792 c, g dbSNP:143599784
1799 1799 a, c dbSNP:541614172
1806 1806 a, g dbSNP:779087611
1824 1824 a, c, t dbSNP:748430882
1825 1825 c, t dbSNP:781203577
1826 1826 c, t dbSNP:745639180
1829 1829 a, g dbSNP:769572476
1832 1832 a, t dbSNP:143140599
1836 1836 c, t dbSNP:762904582
1837 1837 a, g dbSNP:369410913
1838 1838 a, t dbSNP:773828786
1841 1841 c, g dbSNP:761491916
1845 1845 c, t dbSNP:767151038
1848 1848 a, g dbSNP:750843342
1858 1858 a, c dbSNP:760954453
1877 1877 c, t dbSNP:747312519
1878 1878 a, g dbSNP:199554431
1879 1879 a, t dbSNP:369204442
1880 1880 c, t dbSNP:371795291
1885 1885 a, c dbSNP:779177613
1886 1886 a, g, t dbSNP:752824001
1887 1887 a, g dbSNP:769122811
1888 1888 a, t dbSNP:747186769
1890 1890 a, g dbSNP:769505570
1897 1897 a, g dbSNP:545416040
1964 1964 c, g dbSNP:563764666
2061 2061 a, g dbSNP:559647040
2134 2134 g, t dbSNP:776710591
2235 2235 c, g dbSNP:115744316
2245 2245 a, t dbSNP:769938869
2260 2260 a, g dbSNP:148256048
2274 2274 c, t dbSNP:562239793
2280 2280 c, t dbSNP:542330909
2340 2340 c, t dbSNP:561492578
2410 2410 c, t dbSNP:529500424
2421 2421 a, t dbSNP:745408180
2443 2443 c, t dbSNP:541811310
2457 2457 a, g dbSNP:550863021
2539 2539 c, t dbSNP:773449247
2579 2579 g, t dbSNP:117389812
2640 2640 g, t dbSNP:10922153
2644 2644 a, g dbSNP:551890459
2657 2657 c, t dbSNP:575601631
2687 2687 a, g dbSNP:775034377
2690 2690 a, c dbSNP:566913870
2704 2704 a, g dbSNP:534182452
2801 2801 a, t dbSNP:57315298
2807 2807 a, t dbSNP:115075908

Target ORF information:

RefSeq Version NM_030787
Organism Homo sapiens (human)
Definition Homo sapiens complement factor H-related 5 (CFHR5), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1-C-(k)DYK
NM_030787

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
ATGTTGCTCT TATTCAGTGT AATCCTAATC TCATGGGTAT CCACTGTTGG GGGAGAAGGA 
ACACTTTGTG ATTTTCCAAA AATACACCAT GGATTTCTGT ATGATGAAGA AGATTATAAC
CCTTTTTCCC AAGTTCCTAC AGGGGAAGTT TTCTATTACT CCTGTGAATA TAATTTTGTG
TCTCCTTCAA AATCCTTTTG GACTCGCATA ACATGCACAG AAGAAGGATG GTCACCAACA
CCGAAGTGTC TCAGAATGTG TTCCTTTCCT TTTGTGAAAA ATGGTCATTC TGAATCTTCA
GGACTAATAC ATCTGGAAGG TGATACTGTA CAAATTATTT GCAACACAGG ATACAGCCTT
CAAAACAATG AGAAAAACAT TTCGTGTGTA GAACGGGGCT GGTCCACTCC TCCCATATGC
AGCTTCACTA AAGGAGAATG TCATGTTCCA ATTTTAGAAG CCAATGTAGA TGCTCAGCCA
AAAAAAGAAA GCTACAAAGT TGGAGACGTG TTGAAATTCT CCTGCAGAAA AAATCTTATA
AGAGTTGGAT CAGACTCAGT TCAATGTTAC CAATTTGGGT GGTCACCTAA CTTTCCAACA
TGCAAAGGAC AAGTACGATC ATGTGGTCCA CCTCCTCAAC TCTCCAATGG TGAAGTTAAG
GAGATAAGAA AAGAGGAATA TGGACACAAT GAAGTAGTGG AATATGATTG CAATCCTAAT
TTTATAATAA ACGGGCCTAA GAAAATACAA TGTGTGGATG GAGAATGGAC AACTTTACCC
ACTTGTGTTG AACAAGTGAA AACATGTGGA TACATACCTG AACTCGAGTA CGGTTATGTT
CAGCCGTCTG TCCCTCCCTA TCAACATGGA GTTTCAGTCG AGGTGAATTG CAGAAATGAA
TATGCAATGA TTGGAAATAA CATGATTACC TGTATTAATG GAATATGGAC AGAGCTTCCT
ATGTGTGTTG CAACACACCA ACTTAAGAGG TGCAAAATAG CAGGAGTTAA TATAAAAACA
TTACTCAAGC TATCTGGGAA AGAATTTAAT CATAATTCTA GAATACGTTA CAGATGTTCA
GACATCTTCA GATACAGGCA CTCAGTCTGT ATAAACGGGA AATGGAATCC TGAAGTAGAC
TGCACAGAAA AAAGGGAACA ATTCTGCCCA CCGCCACCTC AGATACCTAA TGCTCAGAAT
ATGACAACCA CAGTGAATTA TCAGGATGGA GAAAAAGTAG CTGTTCTCTG TAAAGAAAAC
TATCTACTTC CAGAAGCAAA AGAAATTGTA TGTAAAGATG GACGATGGCA ATCATTACCA
CGCTGTGTTG AGTCTACTGC ATATTGTGGG CCCCCTCCAT CTATTAACAA TGGAGATACC
ACCTCATTCC CATTATCAGT ATATCCTCCA GGGTCAACAG TGACGTACCG TTGCCAGTCC
TTCTATAAAC TCCAGGGCTC TGTAACTGTA ACATGCAGAA ATAAACAGTG GTCAGAACCA
CCAAGATGCC TAGATCCATG TGTGGTATCT GAAGAAAACA TGAACAAAAA TAACATACAG
TTAAAATGGA GAAACGATGG AAAACTCTAT GCAAAAACAG GGGATGCTGT TGAATTCCAG
TGTAAATTCC CACATAAAGC GATGATATCA TCACCACCAT TTCGAGCAAT CTGTCAGGAA
GGGAAATTTG AATATCCTAT ATGTGAATGA

The stop codons will be deleted if pcDNA3.1-C-(k)DYK vector is selected.