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CAMK2A cDNA ORF clone, Homo sapiens (human)

Gene Symbol CAMK2A
Entrez Gene ID 815
Full Name calcium/calmodulin-dependent protein kinase II alpha
Synonyms CAMKA
General protein information
Preferred Names
calcium/calmodulin-dependent protein kinase type II subunit alpha
Names
calcium/calmodulin-dependent protein kinase type II subunit alpha
CaMKIINalpha
CaMK-II alpha subunit
caMK-II subunit alpha
CaM-kinase II alpha chain
CaM kinase II alpha subunit
caM kinase II subunit alpha
calcium/calmodulin-dependent protein kinase II alpha-B subunit
calcium/calmodulin-dependent protein kinase type II alpha chain
calcium/calmodulin-dependent protein kinase (CaM kinase) II alpha
NP_057065.2
NP_741960.1
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

5

5q32

Summary The product of this gene belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Nov 2008]. lac of sum
Disorder MIM:

114078

Disorder Html:





The following CAMK2A gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CAMK2A cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu15670 NM_015981 Homo sapiens calcium/calmodulin-dependent protein kinase II alpha (CAMK2A), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 5-7 $409.00
OHu15931 NM_171825 Homo sapiens calcium/calmodulin-dependent protein kinase II alpha (CAMK2A), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $319.00

*Business Day
**You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.


CloneID OHu15670
Accession Version NM_015981.3 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1470bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product calcium/calmodulin-dependent protein kinase type II subunit alpha isoform 1
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK289776.1, BF951952.1, AC011372.7 and BC040457.1. On Nov 13, 2008 this sequence version replaced gi:25952113. Summary: The product of this gene belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Nov 2008]. Transcript Variant: This variant (1) represents the longer transcript, and it encodes the longer protein (isoform 1). Sequence Note: The RefSeq transcript and protein were derived from transcript and genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK289776.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1966682, SAMEA1968189 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
ATGGCCACCA TCACCTGCAC CCGCTTCACG GAAGAGTACC AGCTCTTCGA GGAATTGGGC 
AAGGGAGCCT TCTCGGTGGT GCGAAGGTGT GTGAAGGTGC TGGCTGGCCA GGAGTATGCT
GCCAAGATCA TCAACACAAA GAAGCTGTCA GCCAGAGACC ATCAGAAGCT GGAGCGTGAA
GCCCGCATCT GCCGCCTGCT GAAGCACCCC AACATCGTCC GACTACATGA CAGCATCTCA
GAGGAGGGAC ACCACTACCT GATCTTCGAC CTGGTCACTG GTGGGGAACT GTTTGAAGAT
ATCGTGGCCC GGGAGTATTA CAGTGAGGCG GATGCCAGTC ACTGTATCCA GCAGATCCTG
GAGGCTGTGC TGCACTGCCA CCAGATGGGG GTGGTGCACC GGGACCTGAA GCCTGAGAAT
CTGTTGCTGG CCTCCAAGCT CAAGGGTGCC GCAGTGAAGC TGGCAGACTT TGGCCTGGCC
ATAGAGGTGG AGGGGGAGCA GCAGGCATGG TTTGGGTTTG CAGGGACTCC TGGATATCTC
TCCCCAGAAG TGCTGCGGAA GGACCCGTAC GGGAAGCCTG TGGACCTGTG GGCTTGTGGG
GTCATCCTGT ACATCCTGCT GGTTGGGTAC CCCCCGTTCT GGGATGAGGA CCAGCACCGC
CTGTACCAGC AGATCAAAGC CGGCGCCTAT GATTTCCCAT CGCCGGAATG GGACACTGTC
ACCCCGGAAG CCAAGGATCT GATCAATAAG ATGCTGACCA TTAACCCATC CAAACGCATC
ACAGCTGCCG AAGCCCTTAA GCACCCCTGG ATCTCGCACC GCTCCACCGT GGCATCCTGC
ATGCACAGAC AGGAGACCGT GGACTGCCTG AAGAAGTTCA ATGCCAGGAG GAAACTGAAG
GGAGCCATTC TCACCACGAT GCTGGCCACC AGGAACTTCT CCGGAGGGAA GAGTGGGGGA
AACAAGAAGA GCGATGGTGT GAAGAAAAGA AAGTCCAGTT CCAGCGTTCA GTTAATGGAA
TCCTCAGAGA GCACCAACAC CACCATCGAG GATGAAGACA CCAAAGTGCG GAAACAGGAA
ATTATAAAAG TGACAGAGCA GCTGATTGAA GCCATAAGCA ATGGAGATTT TGAGTCCTAC
ACGAAGATGT GCGACCCTGG CATGACAGCC TTCGAACCTG AGGCCCTGGG GAACCTGGTT
GAGGGCCTGG ACTTCCATCG ATTCTATTTT GAAAACCTGT GGTCCCGGAA CAGCAAGCCC
GTGCACACCA CCATCCTGAA TCCCCACATC CACCTGATGG GCGACGAGTC AGCCTGCATC
GCCTACATCC GCATCACGCA GTACCTGGAC GCTGGCGGCA TCCCACGCAC CGCCCAGTCG
GAGGAGACCC GTGTCTGGCA CCGCCGGGAT GGCAAATGGC AGATCGTCCA CTTCCACAGA
TCTGGGGCGC CCTCCGTCCT GCCCCACTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeqNP_057065.2
CDS216..1685
Misc Feature(1)45..47(+)
Misc Feature(2)246..1121(+)
Misc Feature(3)252..1028(+)
Misc Feature(4)270..755(+)
Misc Feature(5)270..683(+)
Misc Feature(6)282..755(+)
Misc Feature(7)678..749(+)
Misc Feature(8)1071..1073(+)
Misc Feature(9)1083..1115(+)
Misc Feature(10)1092..1121(+)
Misc Feature(11)1128..1130(+)
Misc Feature(12)1284..1667(+)
Exon (1)1..277
Gene:CAMK2A
Gene Synonym:
Exon (2)278..372
Gene:CAMK2A
Gene Synonym:
Exon (3)373..432
Gene:CAMK2A
Gene Synonym:
Exon (4)433..487
Gene:CAMK2A
Gene Synonym:
Exon (5)488..553
Gene:CAMK2A
Gene Synonym:
Exon (6)554..626
Gene:CAMK2A
Gene Synonym:
Exon (7)627..729
Gene:CAMK2A
Gene Synonym:
Exon (8)730..813
Gene:CAMK2A
Gene Synonym:
Exon (9)814..908
Gene:CAMK2A
Gene Synonym:
Exon (10)909..1031
Gene:CAMK2A
Gene Synonym:
Exon (11)1032..1115
Gene:CAMK2A
Gene Synonym:
Exon (12)1116..1158
Gene:CAMK2A
Gene Synonym:
Exon (13)1159..1199
Gene:CAMK2A
Gene Synonym:
Exon (14)1200..1232
Gene:CAMK2A
Gene Synonym:
Exon (15)1233..1281
Gene:CAMK2A
Gene Synonym:
Exon (16)1282..1357
Gene:CAMK2A
Gene Synonym:
Exon (17)1358..1452
Gene:CAMK2A
Gene Synonym:
Exon (18)1453..1681
Gene:CAMK2A
Gene Synonym:
Exon (19)1682..4904
Gene:CAMK2A
Gene Synonym:
Translation
Position Chain Variation Link
27 27 c, t dbSNP:543751902
35 35 c, t dbSNP:531721850
36 36 g, t dbSNP:564568749
37 37 c, t dbSNP:551309706
76 76 c, t dbSNP:775323226
82 82 c, g dbSNP:748564351
94 94 c, t dbSNP:572339404
113 113 a, g dbSNP:114371823
128 128 c, g dbSNP:542165088
139 139 c, t dbSNP:149774361
140 140 a, g dbSNP:555898216
145 145 c, t dbSNP:112264872
165 165 c, t dbSNP:537817124
168 168 a, g dbSNP:775766069
172 172 c, t dbSNP:772598947
177 177 a, c, t dbSNP:373285975
179 179 a, c dbSNP:11539000
187 187 a, c dbSNP:770341733
192 192 c, g dbSNP:749026222
196 196 c, t dbSNP:777303710
206 206 c, t dbSNP:755724600
207 207 a, c dbSNP:747983626
208 208 g, t dbSNP:184860162
209 209 c, t dbSNP:558645371
210 210 a, g dbSNP:751507916
215 215 a, g dbSNP:765428269
219 219 a, g dbSNP:757273062
230 230 c, t dbSNP:753901371
238 238 a, g dbSNP:764230609
243 243 a, t dbSNP:6861622
245 245 a, g dbSNP:760847773
263 263 c, t dbSNP:753516638
270 270 c, t dbSNP:767848402
275 275 a, c dbSNP:760077353
290 290 a, g, t dbSNP:759905592
297 297 c, t dbSNP:751885208
327 327 a, g dbSNP:766825548
368 368 c, t dbSNP:56178981
370 370 c, g dbSNP:202217757
376 376 a, t dbSNP:750935357
386 386 a, g dbSNP:764895828
390 390 c, t dbSNP:761424198
395 395 a, g dbSNP:776217899
398 398 c, t dbSNP:763874013
399 399 c, t dbSNP:544705728
410 410 c, g dbSNP:55877006
431 431 c, t dbSNP:775198222
435 435 c, g dbSNP:61732056
440 440 a, g dbSNP:759379098
450 450 a, g dbSNP:202107716
455 455 a, g dbSNP:770876692
470 470 c, t dbSNP:749201486
479 479 c, t dbSNP:372258019
482 482 c, t dbSNP:73268710
503 503 a, g dbSNP:769557562
518 518 c, t dbSNP:373136765
527 527 a, g dbSNP:55856831
544 544 c, t dbSNP:779607303
545 545 a, c, g dbSNP:200008559
569 569 a, g dbSNP:770381077
585 585 c, g dbSNP:758821296
611 611 a, g dbSNP:748571681
615 615 c, t dbSNP:780817639
662 662 c, t dbSNP:756197069
665 665 c, g, t dbSNP:373461784
677 677 a, g dbSNP:370266511
698 698 a, t dbSNP:758099130
702 702 g, t dbSNP:745482187
720 720 g, t dbSNP:778835439
722 722 a, t dbSNP:756990611
740 740 a, g dbSNP:745592475
758 758 c, t dbSNP:778444660
782 782 a, g, t dbSNP:748592274
785 785 c, t dbSNP:377296803
786 786 g, t dbSNP:756158214
788 788 a, g dbSNP:373849502
792 792 c, g dbSNP:370600720
824 824 c, g dbSNP:756390584
830 830 c, t dbSNP:762748019
831 831 c, t dbSNP:773007368
833 833 g, t dbSNP:769504130
844 844 a, c dbSNP:747987338
845 845 c, t dbSNP:781084361
851 851 a, g dbSNP:752482081
871 871 a, t dbSNP:11956781
872 872 c, t dbSNP:746935527
873 873 -, ccc dbSNP:150670811
878 878 g, t dbSNP:778928887
882 882 a, c dbSNP:17854002
896 896 c, t dbSNP:201482484
899 899 c, t dbSNP:749308142
908 908 a, c, t dbSNP:368023327
914 914 a, g dbSNP:756380543
917 917 a, g dbSNP:371411676
920 920 a, g, t dbSNP:368367831
940 940 c, t dbSNP:751800259
941 941 a, g dbSNP:186348077
997 997 c, t dbSNP:758925573
1004 1004 c, t dbSNP:142245972
1009 1009 c, g dbSNP:764807945
1010 1010 c, t dbSNP:761627935
1018 1018 a, g dbSNP:568397508
1034 1034 c, t dbSNP:756841326
1035 1035 c, t dbSNP:200216623
1050 1050 -, g dbSNP:35495165
1073 1073 c, t dbSNP:570919176
1097 1097 c, t dbSNP:760199575
1133 1133 a, g, t dbSNP:757665103
1142 1142 c, t dbSNP:375270263
1157 1157 c, t dbSNP:753413943
1171 1171 a, g dbSNP:765165346
1178 1178 c, g, t dbSNP:55696902
1187 1187 c, t dbSNP:375813680
1196 1196 a, g dbSNP:759813255
1220 1220 c, t dbSNP:533694395
1244 1244 a, g dbSNP:770841322
1262 1262 c, t dbSNP:754671966
1284 1284 a, c, t dbSNP:745982580
1285 1285 a, g dbSNP:778942662
1299 1299 a, g dbSNP:757512233
1307 1307 a, g dbSNP:749509563
1313 1313 a, g dbSNP:778172176
1355 1355 c, t dbSNP:756516852
1367 1367 c, t dbSNP:375087065
1388 1388 c, t dbSNP:559912434
1406 1406 a, g dbSNP:371839355
1408 1408 a, t dbSNP:764964453
1427 1427 a, c dbSNP:761351468
1434 1434 c, t dbSNP:753708011
1450 1450 a, c dbSNP:763794315
1452 1452 a, c, t dbSNP:376699738
1454 1454 a, g dbSNP:376988214
1475 1475 c, t dbSNP:373786921
1476 1476 a, g dbSNP:772746827
1487 1487 c, g dbSNP:746357880
1490 1490 c, t dbSNP:369670780
1502 1502 c, t dbSNP:575572630
1503 1503 a, t dbSNP:756733402
1511 1511 a, g dbSNP:557617370
1517 1517 c, t dbSNP:376355423
1535 1535 c, t dbSNP:200745191
1536 1536 a, g dbSNP:752541567
1545 1545 c, t dbSNP:767291853
1546 1546 a, g dbSNP:754962340
1547 1547 c, t dbSNP:751462243
1552 1552 c, t dbSNP:766270888
1562 1562 a, g dbSNP:761828003
1565 1565 c, t dbSNP:373201434
1566 1566 a, g dbSNP:374924411
1567 1567 c, g dbSNP:760949012
1569 1569 a, g dbSNP:199592588
1571 1571 c, t dbSNP:776065787
1572 1572 a, g dbSNP:772552968
1577 1577 c, t dbSNP:746187422
1583 1583 c, t dbSNP:199578629
1586 1586 c, t dbSNP:771431817
1587 1587 a, g dbSNP:748774194
1594 1594 c, t dbSNP:777247730
1595 1595 a, g dbSNP:371342042
1605 1605 c, t dbSNP:367551385
1606 1606 a, g dbSNP:780762936
1610 1610 c, t dbSNP:41287120
1617 1617 c, t dbSNP:754732557
1618 1618 a, g dbSNP:375918851
1620 1620 a, c dbSNP:577586528
1625 1625 c, t dbSNP:2241694
1638 1638 a, g dbSNP:753904024
1641 1641 a, g dbSNP:764264581
1643 1643 c, t dbSNP:202174183
1661 1661 a, g dbSNP:752981792
1663 1663 c, t dbSNP:767783317
1664 1664 a, g dbSNP:759852005
1670 1670 c, t dbSNP:192861753
1671 1671 a, g dbSNP:771394411
1678 1678 a, c dbSNP:763490198
1696 1696 c, g, t dbSNP:768232346
1702 1702 c, g, t dbSNP:563702310
1703 1703 a, g, t dbSNP:545697976
1706 1706 a, g dbSNP:779026434
1707 1707 c, t dbSNP:201811573
1708 1708 a, g dbSNP:374575000
1714 1714 a, g dbSNP:369901307
1718 1718 c, t dbSNP:755226405
1719 1719 a, g dbSNP:751816059
1720 1720 c, t dbSNP:150250733
1721 1721 a, g dbSNP:756921569
1729 1729 a, c, g dbSNP:372475680
1733 1733 -, tg dbSNP:61217791
1734 1734 -, gt dbSNP:140679603
1737 1737 c, t dbSNP:75000324
1754 1754 a, g dbSNP:765780167
1758 1758 a, c dbSNP:762275291
1761 1761 c, g dbSNP:776071504
1763 1763 a, g dbSNP:573824652
1768 1768 a, g dbSNP:760046210
1797 1797 a, c dbSNP:775220318
1803 1803 c, t dbSNP:141071420
1806 1806 -, c dbSNP:761561805
1806 1806 c, t dbSNP:745686978
1817 1817 g, t dbSNP:774254394
1820 1820 a, c dbSNP:771037753
1829 1829 c, g dbSNP:151118217
1839 1839 c, t dbSNP:777509465
1842 1842 c, t dbSNP:765564257
1855 1855 c, g, t dbSNP:115797668
1856 1856 c, t dbSNP:758589408
1869 1869 c, t dbSNP:551245232
1874 1874 a, g dbSNP:562834086
1889 1889 c, t dbSNP:565830737
1896 1896 c, t dbSNP:754367641
1900 1900 a, c dbSNP:546627283
1903 1903 c, t dbSNP:528452188
1985 1985 g, t dbSNP:780881398
1991 1991 c, t dbSNP:112896997
2004 2004 a, g dbSNP:760749643
2019 2019 c, t dbSNP:549087104
2023 2023 c, t dbSNP:530874070
2024 2024 -, t dbSNP:33920720
2025 2025 -, t dbSNP:5872172
2026 2026 -, g dbSNP:374563226
2043 2043 a, g dbSNP:563916786
2069 2069 a, g dbSNP:2217641
2081 2081 c, t dbSNP:545225283
2086 2086 c, g dbSNP:370722785
2100 2100 c, t dbSNP:184203395
2122 2122 a, g dbSNP:767757040
2130 2130 a, g dbSNP:957710
2132 2132 a, g dbSNP:957709
2162 2162 a, g dbSNP:376905162
2173 2173 a, g dbSNP:555375816
2186 2186 c, t dbSNP:543560329
2187 2187 a, g dbSNP:749177493
2190 2190 c, t dbSNP:374631793
2191 2191 a, g dbSNP:576005520
2198 2198 a, g dbSNP:145916509
2218 2218 c, t dbSNP:140231558
2236 2236 c, t dbSNP:539900482
2262 2262 c, t dbSNP:572607568
2309 2309 a, g dbSNP:554114532
2343 2343 a, t dbSNP:553628592
2368 2368 a, g dbSNP:780619214
2386 2386 c, g dbSNP:7448702
2389 2389 a, c dbSNP:373456869
2391 2391 g, t dbSNP:371373892
2394 2394 c, t dbSNP:548923924
2396 2396 a, g dbSNP:531039633
2446 2446 a, g dbSNP:570050508
2470 2470 c, g dbSNP:1064129
2506 2506 c, t dbSNP:551991956
2507 2507 a, g dbSNP:752734160
2520 2520 a, g dbSNP:79354200
2521 2521 c, t dbSNP:746674731
2522 2522 a, g dbSNP:560119760
2600 2600 a, g dbSNP:541770238
2629 2629 -, t dbSNP:35164363
2645 2645 -, t dbSNP:537846929
2646 2646 -, g dbSNP:747281210
2646 2646 g, t dbSNP:201670618
2681 2681 c, t dbSNP:529578992
2693 2693 c, g, t dbSNP:7732895
2694 2694 a, g dbSNP:192111888
2747 2747 a, t dbSNP:143235845
2756 2756 c, t dbSNP:570833066
2757 2757 a, g dbSNP:187749277
2841 2841 c, t dbSNP:546006206
2847 2847 g, t dbSNP:755350646
2878 2878 a, g dbSNP:539753446
2902 2902 a, g dbSNP:184845639
2931 2931 a, g dbSNP:35651593
2947 2947 -, c dbSNP:34429496
3008 3008 a, c, t dbSNP:556864595
3009 3009 a, g dbSNP:567968447
3011 3011 c, t dbSNP:11952641
3013 3013 c, g dbSNP:191193183
3020 3020 a, g dbSNP:78265902
3032 3032 -, g dbSNP:34864007
3050 3050 a, g dbSNP:570166639
3069 3069 c, t dbSNP:746199208
3076 3076 a, g dbSNP:59633008
3103 3103 c, t dbSNP:113163901
3112 3112 c, t dbSNP:756627754
3158 3158 -, actgtct dbSNP:767643124
3159 3159 c, t dbSNP:187757305
3192 3192 a, c dbSNP:547971932
3193 3193 a, g dbSNP:750484768
3216 3216 a, c dbSNP:529658277
3220 3220 a, c dbSNP:562357916
3238 3238 -, aaaac dbSNP:762027741
3241 3241 -, a dbSNP:766939686
3274 3274 a, t dbSNP:78529899
3302 3302 a, g dbSNP:767524503
3346 3346 c, g dbSNP:549779315
3368 3368 c, t dbSNP:112597831
3406 3406 a, g dbSNP:182629016
3413 3413 a, c, g dbSNP:72837583
3439 3439 c, t dbSNP:34266615
3443 3443 c, t dbSNP:749346291
3474 3474 c, g dbSNP:149933620
3488 3488 c, t dbSNP:571766100
3489 3489 a, g dbSNP:79207651
3509 3509 c, t dbSNP:541622938
3510 3510 a, g dbSNP:6869490
3512 3512 c, t dbSNP:370847074
3526 3526 c, t dbSNP:556024193
3553 3553 c, t dbSNP:191256988
3577 3577 a, g dbSNP:746245033
3612 3612 c, t dbSNP:576384293
3614 3614 g, t dbSNP:769836752
3623 3623 c, t dbSNP:558100344
3636 3636 c, t dbSNP:759435022
3644 3644 c, t dbSNP:539560967
3680 3680 -, a dbSNP:750759815
3698 3698 -, c dbSNP:34655241
3714 3714 c, t dbSNP:1056039
3728 3728 a, c dbSNP:187985136
3759 3759 c, t dbSNP:548048677
3786 3786 c, t dbSNP:536039480
3791 3791 c, g dbSNP:183021002
3801 3801 c, t dbSNP:547199963
3809 3809 a, g dbSNP:531997567
3848 3848 c, t dbSNP:530134149
3849 3849 a, g dbSNP:770372502
3858 3858 c, g dbSNP:563933970
3882 3882 c, t dbSNP:10038918
3935 3935 c, t dbSNP:190785277
3953 3953 c, t dbSNP:777408020
3991 3991 c, t dbSNP:139169139
3996 3996 c, t dbSNP:559808389
3998 3998 c, t dbSNP:186399006
4039 4039 c, g, t dbSNP:574271571
4062 4062 c, t dbSNP:562677803
4101 4101 g, t dbSNP:544197979
4104 4104 a, g dbSNP:111466577
4117 4117 a, g dbSNP:73796375
4119 4119 c, g dbSNP:550889299
4136 4136 -, t dbSNP:569049701
4156 4156 g, t dbSNP:182017467
4204 4204 c, t dbSNP:539809598
4234 4234 g, t dbSNP:780436184
4320 4320 c, t dbSNP:572605070
4340 4340 c, t dbSNP:564690788
4352 4352 c, t dbSNP:554283274
4353 4353 a, g dbSNP:756959817
4372 4372 c, t dbSNP:116563155
4410 4410 c, t dbSNP:2163766
4413 4413 c, t dbSNP:550308584
4463 4463 a, c dbSNP:757808056
4472 4472 a, g dbSNP:538157761
4482 4482 a, g dbSNP:571119766
4510 4510 -, a dbSNP:376082789
4511 4511 -, a, aa dbSNP:386405298
4512 4512 -, a dbSNP:34777554
4521 4521 -, a, taataa dbSNP:138971440
4522 4522 -, taa dbSNP:147490193
4535 4535 -, aat dbSNP:57339321
4584 4584 c, t dbSNP:6882623
4636 4636 c, t dbSNP:527278402
4734 4734 g, t dbSNP:15645
4743 4743 -, t dbSNP:397724114
4750 4750 -, tttttcttttctttttt dbSNP:200240393
4753 4753 -, t dbSNP:11398735
4754 4754 -, t dbSNP:535528051
4755 4755 c, g, t dbSNP:111509060
4772 4772 a, t dbSNP:566258154
4790 4790 a, t dbSNP:192040695
4820 4820 a, g, t dbSNP:13173132
4822 4822 g, t dbSNP:6882312
4823 4823 a, g, t dbSNP:1056045
4824 4824 g, t dbSNP:7721896
4825 4825 c, g dbSNP:200391443
4826 4826 -, gc dbSNP:375452482
4827 4827 -, cgg dbSNP:199517991
4827 4827 -, cg dbSNP:138156987
4827 4827 -, c dbSNP:10609501
4827 4827 c, g dbSNP:113096177
4830 4830 -, gg dbSNP:199658748
4831 4831 -, tg dbSNP:758481941
4831 4831 -, t dbSNP:773237274
4838 4838 g, t dbSNP:565168735
4842 4842 a, g dbSNP:10038061
4845 4845 a, g dbSNP:10038060
4849 4849 a, c dbSNP:375378601
4850 4850 a, g dbSNP:114959506
4862 4862 c, t dbSNP:563147489
4867 4867 g, t dbSNP:10043606
4890 4890 a, g dbSNP:147430614

Target ORF information:

RefSeq Version NM_015981
Organism Homo sapiens (human)
Definition Homo sapiens calcium/calmodulin-dependent protein kinase II alpha (CAMK2A), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_015981

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
ATGGCCACCA TCACCTGCAC CCGCTTCACG GAAGAGTACC AGCTCTTCGA GGAATTGGGC 
AAGGGAGCCT TCTCGGTGGT GCGAAGGTGT GTGAAGGTGC TGGCTGGCCA GGAGTATGCT
GCCAAGATCA TCAACACAAA GAAGCTGTCA GCCAGAGACC ATCAGAAGCT GGAGCGTGAA
GCCCGCATCT GCCGCCTGCT GAAGCACCCC AACATCGTCC GACTACATGA CAGCATCTCA
GAGGAGGGAC ACCACTACCT GATCTTCGAC CTGGTCACTG GTGGGGAACT GTTTGAAGAT
ATCGTGGCCC GGGAGTATTA CAGTGAGGCG GATGCCAGTC ACTGTATCCA GCAGATCCTG
GAGGCTGTGC TGCACTGCCA CCAGATGGGG GTGGTGCACC GGGACCTGAA GCCTGAGAAT
CTGTTGCTGG CCTCCAAGCT CAAGGGTGCC GCAGTGAAGC TGGCAGACTT TGGCCTGGCC
ATAGAGGTGG AGGGGGAGCA GCAGGCATGG TTTGGGTTTG CAGGGACTCC TGGATATCTC
TCCCCAGAAG TGCTGCGGAA GGACCCGTAC GGGAAGCCTG TGGACCTGTG GGCTTGTGGG
GTCATCCTGT ACATCCTGCT GGTTGGGTAC CCCCCGTTCT GGGATGAGGA CCAGCACCGC
CTGTACCAGC AGATCAAAGC CGGCGCCTAT GATTTCCCAT CGCCGGAATG GGACACTGTC
ACCCCGGAAG CCAAGGATCT GATCAATAAG ATGCTGACCA TTAACCCATC CAAACGCATC
ACAGCTGCCG AAGCCCTTAA GCACCCCTGG ATCTCGCACC GCTCCACCGT GGCATCCTGC
ATGCACAGAC AGGAGACCGT GGACTGCCTG AAGAAGTTCA ATGCCAGGAG GAAACTGAAG
GGAGCCATTC TCACCACGAT GCTGGCCACC AGGAACTTCT CCGGAGGGAA GAGTGGGGGA
AACAAGAAGA GCGATGGTGT GAAGAAAAGA AAGTCCAGTT CCAGCGTTCA GTTAATGGAA
TCCTCAGAGA GCACCAACAC CACCATCGAG GATGAAGACA CCAAAGTGCG GAAACAGGAA
ATTATAAAAG TGACAGAGCA GCTGATTGAA GCCATAAGCA ATGGAGATTT TGAGTCCTAC
ACGAAGATGT GCGACCCTGG CATGACAGCC TTCGAACCTG AGGCCCTGGG GAACCTGGTT
GAGGGCCTGG ACTTCCATCG ATTCTATTTT GAAAACCTGT GGTCCCGGAA CAGCAAGCCC
GTGCACACCA CCATCCTGAA TCCCCACATC CACCTGATGG GCGACGAGTC AGCCTGCATC
GCCTACATCC GCATCACGCA GTACCTGGAC GCTGGCGGCA TCCCACGCAC CGCCCAGTCG
GAGGAGACCC GTGTCTGGCA CCGCCGGGAT GGCAAATGGC AGATCGTCCA CTTCCACAGA
TCTGGGGCGC CCTCCGTCCT GCCCCACTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu15931
Accession Version NM_171825.2 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1437bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product calcium/calmodulin-dependent protein kinase type II subunit alpha isoform 2
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK289776.1, AB023185.1, BF951952.1, AC011372.7 and BC040457.1. On Nov 13, 2008 this sequence version replaced gi:25952117. Summary: The product of this gene belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Nov 2008]. Transcript Variant: This variant (2) lacks an in-frame segment of the coding region, compared to variant 1. It encodes a shorter protein (isoform 2), that is missing an internal segment when it is compared to isoform 1. Sequence Note: The RefSeq transcript and protein were derived from transcript and genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC040457.1, AB023185.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145743 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
ATGGCCACCA TCACCTGCAC CCGCTTCACG GAAGAGTACC AGCTCTTCGA GGAATTGGGC 
AAGGGAGCCT TCTCGGTGGT GCGAAGGTGT GTGAAGGTGC TGGCTGGCCA GGAGTATGCT
GCCAAGATCA TCAACACAAA GAAGCTGTCA GCCAGAGACC ATCAGAAGCT GGAGCGTGAA
GCCCGCATCT GCCGCCTGCT GAAGCACCCC AACATCGTCC GACTACATGA CAGCATCTCA
GAGGAGGGAC ACCACTACCT GATCTTCGAC CTGGTCACTG GTGGGGAACT GTTTGAAGAT
ATCGTGGCCC GGGAGTATTA CAGTGAGGCG GATGCCAGTC ACTGTATCCA GCAGATCCTG
GAGGCTGTGC TGCACTGCCA CCAGATGGGG GTGGTGCACC GGGACCTGAA GCCTGAGAAT
CTGTTGCTGG CCTCCAAGCT CAAGGGTGCC GCAGTGAAGC TGGCAGACTT TGGCCTGGCC
ATAGAGGTGG AGGGGGAGCA GCAGGCATGG TTTGGGTTTG CAGGGACTCC TGGATATCTC
TCCCCAGAAG TGCTGCGGAA GGACCCGTAC GGGAAGCCTG TGGACCTGTG GGCTTGTGGG
GTCATCCTGT ACATCCTGCT GGTTGGGTAC CCCCCGTTCT GGGATGAGGA CCAGCACCGC
CTGTACCAGC AGATCAAAGC CGGCGCCTAT GATTTCCCAT CGCCGGAATG GGACACTGTC
ACCCCGGAAG CCAAGGATCT GATCAATAAG ATGCTGACCA TTAACCCATC CAAACGCATC
ACAGCTGCCG AAGCCCTTAA GCACCCCTGG ATCTCGCACC GCTCCACCGT GGCATCCTGC
ATGCACAGAC AGGAGACCGT GGACTGCCTG AAGAAGTTCA ATGCCAGGAG GAAACTGAAG
GGAGCCATTC TCACCACGAT GCTGGCCACC AGGAACTTCT CCGGAGGGAA GAGTGGGGGA
AACAAGAAGA GCGATGGTGT GAAGGAATCC TCAGAGAGCA CCAACACCAC CATCGAGGAT
GAAGACACCA AAGTGCGGAA ACAGGAAATT ATAAAAGTGA CAGAGCAGCT GATTGAAGCC
ATAAGCAATG GAGATTTTGA GTCCTACACG AAGATGTGCG ACCCTGGCAT GACAGCCTTC
GAACCTGAGG CCCTGGGGAA CCTGGTTGAG GGCCTGGACT TCCATCGATT CTATTTTGAA
AACCTGTGGT CCCGGAACAG CAAGCCCGTG CACACCACCA TCCTGAATCC CCACATCCAC
CTGATGGGCG ACGAGTCAGC CTGCATCGCC TACATCCGCA TCACGCAGTA CCTGGACGCT
GGCGGCATCC CACGCACCGC CCAGTCGGAG GAGACCCGTG TCTGGCACCG CCGGGATGGC
AAATGGCAGA TCGTCCACTT CCACAGATCT GGGGCGCCCT CCGTCCTGCC CCACTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeqNP_741960.1
CDS216..1652
Misc Feature(1)45..47(+)
Misc Feature(2)246..1121(+)
Misc Feature(3)252..1028(+)
Misc Feature(4)270..755(+)
Misc Feature(5)270..683(+)
Misc Feature(6)282..755(+)
Misc Feature(7)678..749(+)
Misc Feature(8)1071..1073(+)
Misc Feature(9)1083..1115(+)
Misc Feature(10)1092..1121(+)
Misc Feature(11)1128..1130(+)
Misc Feature(12)1143..1175(+)
Misc Feature(13)1251..1634(+)
Exon (1)1..277
Gene:CAMK2A
Gene Synonym:
Exon (2)278..372
Gene:CAMK2A
Gene Synonym:
Exon (3)373..432
Gene:CAMK2A
Gene Synonym:
Exon (4)433..487
Gene:CAMK2A
Gene Synonym:
Exon (5)488..553
Gene:CAMK2A
Gene Synonym:
Exon (6)554..626
Gene:CAMK2A
Gene Synonym:
Exon (7)627..729
Gene:CAMK2A
Gene Synonym:
Exon (8)730..813
Gene:CAMK2A
Gene Synonym:
Exon (9)814..908
Gene:CAMK2A
Gene Synonym:
Exon (10)909..1031
Gene:CAMK2A
Gene Synonym:
Exon (11)1032..1115
Gene:CAMK2A
Gene Synonym:
Exon (12)1116..1158
Gene:CAMK2A
Gene Synonym:
Exon (13)1159..1199
Gene:CAMK2A
Gene Synonym:
Exon (14)1200..1248
Gene:CAMK2A
Gene Synonym:
Exon (15)1249..1324
Gene:CAMK2A
Gene Synonym:
Exon (16)1325..1419
Gene:CAMK2A
Gene Synonym:
Exon (17)1420..1648
Gene:CAMK2A
Gene Synonym:
Exon (18)1649..4871
Gene:CAMK2A
Gene Synonym:
Translation
Position Chain Variation Link
27 27 c, t dbSNP:543751902
35 35 c, t dbSNP:531721850
36 36 g, t dbSNP:564568749
37 37 c, t dbSNP:551309706
76 76 c, t dbSNP:775323226
82 82 c, g dbSNP:748564351
94 94 c, t dbSNP:572339404
113 113 a, g dbSNP:114371823
128 128 c, g dbSNP:542165088
139 139 c, t dbSNP:149774361
140 140 a, g dbSNP:555898216
145 145 c, t dbSNP:112264872
165 165 c, t dbSNP:537817124
168 168 a, g dbSNP:775766069
172 172 c, t dbSNP:772598947
177 177 a, c, t dbSNP:373285975
179 179 a, c dbSNP:11539000
187 187 a, c dbSNP:770341733
192 192 c, g dbSNP:749026222
196 196 c, t dbSNP:777303710
206 206 c, t dbSNP:755724600
207 207 a, c dbSNP:747983626
208 208 g, t dbSNP:184860162
209 209 c, t dbSNP:558645371
210 210 a, g dbSNP:751507916
215 215 a, g dbSNP:765428269
219 219 a, g dbSNP:757273062
230 230 c, t dbSNP:753901371
238 238 a, g dbSNP:764230609
243 243 a, t dbSNP:6861622
245 245 a, g dbSNP:760847773
263 263 c, t dbSNP:753516638
270 270 c, t dbSNP:767848402
275 275 a, c dbSNP:760077353
290 290 a, g, t dbSNP:759905592
297 297 c, t dbSNP:751885208
327 327 a, g dbSNP:766825548
368 368 c, t dbSNP:56178981
370 370 c, g dbSNP:202217757
376 376 a, t dbSNP:750935357
386 386 a, g dbSNP:764895828
390 390 c, t dbSNP:761424198
395 395 a, g dbSNP:776217899
398 398 c, t dbSNP:763874013
399 399 c, t dbSNP:544705728
410 410 c, g dbSNP:55877006
431 431 c, t dbSNP:775198222
435 435 c, g dbSNP:61732056
440 440 a, g dbSNP:759379098
450 450 a, g dbSNP:202107716
455 455 a, g dbSNP:770876692
470 470 c, t dbSNP:749201486
479 479 c, t dbSNP:372258019
482 482 c, t dbSNP:73268710
503 503 a, g dbSNP:769557562
518 518 c, t dbSNP:373136765
527 527 a, g dbSNP:55856831
544 544 c, t dbSNP:779607303
545 545 a, c, g dbSNP:200008559
569 569 a, g dbSNP:770381077
585 585 c, g dbSNP:758821296
611 611 a, g dbSNP:748571681
615 615 c, t dbSNP:780817639
662 662 c, t dbSNP:756197069
665 665 c, g, t dbSNP:373461784
677 677 a, g dbSNP:370266511
698 698 a, t dbSNP:758099130
702 702 g, t dbSNP:745482187
720 720 g, t dbSNP:778835439
722 722 a, t dbSNP:756990611
740 740 a, g dbSNP:745592475
758 758 c, t dbSNP:778444660
782 782 a, g, t dbSNP:748592274
785 785 c, t dbSNP:377296803
786 786 g, t dbSNP:756158214
788 788 a, g dbSNP:373849502
792 792 c, g dbSNP:370600720
824 824 c, g dbSNP:756390584
830 830 c, t dbSNP:762748019
831 831 c, t dbSNP:773007368
833 833 g, t dbSNP:769504130
844 844 a, c dbSNP:747987338
845 845 c, t dbSNP:781084361
851 851 a, g dbSNP:752482081
871 871 a, t dbSNP:11956781
872 872 c, t dbSNP:746935527
873 873 -, ccc dbSNP:150670811
878 878 g, t dbSNP:778928887
882 882 a, c dbSNP:17854002
896 896 c, t dbSNP:201482484
899 899 c, t dbSNP:749308142
908 908 a, c, t dbSNP:368023327
914 914 a, g dbSNP:756380543
917 917 a, g dbSNP:371411676
920 920 a, g, t dbSNP:368367831
940 940 c, t dbSNP:751800259
941 941 a, g dbSNP:186348077
997 997 c, t dbSNP:758925573
1004 1004 c, t dbSNP:142245972
1009 1009 c, g dbSNP:764807945
1010 1010 c, t dbSNP:761627935
1018 1018 a, g dbSNP:568397508
1034 1034 c, t dbSNP:756841326
1035 1035 c, t dbSNP:200216623
1050 1050 -, g dbSNP:35495165
1073 1073 c, t dbSNP:570919176
1097 1097 c, t dbSNP:760199575
1133 1133 a, g, t dbSNP:757665103
1142 1142 c, t dbSNP:375270263
1157 1157 c, t dbSNP:753413943
1171 1171 a, g dbSNP:765165346
1178 1178 c, g, t dbSNP:55696902
1187 1187 c, t dbSNP:375813680
1196 1196 a, g dbSNP:759813255
1211 1211 a, g dbSNP:770841322
1229 1229 c, t dbSNP:754671966
1251 1251 a, c, t dbSNP:745982580
1252 1252 a, g dbSNP:778942662
1266 1266 a, g dbSNP:757512233
1274 1274 a, g dbSNP:749509563
1280 1280 a, g dbSNP:778172176
1322 1322 c, t dbSNP:756516852
1334 1334 c, t dbSNP:375087065
1355 1355 c, t dbSNP:559912434
1373 1373 a, g dbSNP:371839355
1375 1375 a, t dbSNP:764964453
1394 1394 a, c dbSNP:761351468
1401 1401 c, t dbSNP:753708011
1417 1417 a, c dbSNP:763794315
1419 1419 a, c, t dbSNP:376699738
1421 1421 a, g dbSNP:376988214
1442 1442 c, t dbSNP:373786921
1443 1443 a, g dbSNP:772746827
1454 1454 c, g dbSNP:746357880
1457 1457 c, t dbSNP:369670780
1469 1469 c, t dbSNP:575572630
1470 1470 a, t dbSNP:756733402
1478 1478 a, g dbSNP:557617370
1484 1484 c, t dbSNP:376355423
1502 1502 c, t dbSNP:200745191
1503 1503 a, g dbSNP:752541567
1512 1512 c, t dbSNP:767291853
1513 1513 a, g dbSNP:754962340
1514 1514 c, t dbSNP:751462243
1519 1519 c, t dbSNP:766270888
1529 1529 a, g dbSNP:761828003
1532 1532 c, t dbSNP:373201434
1533 1533 a, g dbSNP:374924411
1534 1534 c, g dbSNP:760949012
1536 1536 a, g dbSNP:199592588
1538 1538 c, t dbSNP:776065787
1539 1539 a, g dbSNP:772552968
1544 1544 c, t dbSNP:746187422
1550 1550 c, t dbSNP:199578629
1553 1553 c, t dbSNP:771431817
1554 1554 a, g dbSNP:748774194
1561 1561 c, t dbSNP:777247730
1562 1562 a, g dbSNP:371342042
1572 1572 c, t dbSNP:367551385
1573 1573 a, g dbSNP:780762936
1577 1577 c, t dbSNP:41287120
1584 1584 c, t dbSNP:754732557
1585 1585 a, g dbSNP:375918851
1587 1587 a, c dbSNP:577586528
1592 1592 c, t dbSNP:2241694
1605 1605 a, g dbSNP:753904024
1608 1608 a, g dbSNP:764264581
1610 1610 c, t dbSNP:202174183
1628 1628 a, g dbSNP:752981792
1630 1630 c, t dbSNP:767783317
1631 1631 a, g dbSNP:759852005
1637 1637 c, t dbSNP:192861753
1638 1638 a, g dbSNP:771394411
1645 1645 a, c dbSNP:763490198
1663 1663 c, g, t dbSNP:768232346
1669 1669 c, g, t dbSNP:563702310
1670 1670 a, g, t dbSNP:545697976
1673 1673 a, g dbSNP:779026434
1674 1674 c, t dbSNP:201811573
1675 1675 a, g dbSNP:374575000
1681 1681 a, g dbSNP:369901307
1685 1685 c, t dbSNP:755226405
1686 1686 a, g dbSNP:751816059
1687 1687 c, t dbSNP:150250733
1688 1688 a, g dbSNP:756921569
1696 1696 a, c, g dbSNP:372475680
1700 1700 -, tg dbSNP:61217791
1701 1701 -, gt dbSNP:140679603
1704 1704 c, t dbSNP:75000324
1721 1721 a, g dbSNP:765780167
1725 1725 a, c dbSNP:762275291
1728 1728 c, g dbSNP:776071504
1730 1730 a, g dbSNP:573824652
1735 1735 a, g dbSNP:760046210
1764 1764 a, c dbSNP:775220318
1770 1770 c, t dbSNP:141071420
1773 1773 -, c dbSNP:761561805
1773 1773 c, t dbSNP:745686978
1784 1784 g, t dbSNP:774254394
1787 1787 a, c dbSNP:771037753
1796 1796 c, g dbSNP:151118217
1806 1806 c, t dbSNP:777509465
1809 1809 c, t dbSNP:765564257
1822 1822 c, g, t dbSNP:115797668
1823 1823 c, t dbSNP:758589408
1836 1836 c, t dbSNP:551245232
1841 1841 a, g dbSNP:562834086
1856 1856 c, t dbSNP:565830737
1863 1863 c, t dbSNP:754367641
1867 1867 a, c dbSNP:546627283
1870 1870 c, t dbSNP:528452188
1952 1952 g, t dbSNP:780881398
1958 1958 c, t dbSNP:112896997
1971 1971 a, g dbSNP:760749643
1986 1986 c, t dbSNP:549087104
1990 1990 c, t dbSNP:530874070
1991 1991 -, t dbSNP:33920720
1992 1992 -, t dbSNP:5872172
1993 1993 -, g dbSNP:374563226
2010 2010 a, g dbSNP:563916786
2036 2036 a, g dbSNP:2217641
2048 2048 c, t dbSNP:545225283
2053 2053 c, g dbSNP:370722785
2067 2067 c, t dbSNP:184203395
2089 2089 a, g dbSNP:767757040
2097 2097 a, g dbSNP:957710
2099 2099 a, g dbSNP:957709
2129 2129 a, g dbSNP:376905162
2140 2140 a, g dbSNP:555375816
2153 2153 c, t dbSNP:543560329
2154 2154 a, g dbSNP:749177493
2157 2157 c, t dbSNP:374631793
2158 2158 a, g dbSNP:576005520
2165 2165 a, g dbSNP:145916509
2185 2185 c, t dbSNP:140231558
2203 2203 c, t dbSNP:539900482
2229 2229 c, t dbSNP:572607568
2276 2276 a, g dbSNP:554114532
2310 2310 a, t dbSNP:553628592
2335 2335 a, g dbSNP:780619214
2353 2353 c, g dbSNP:7448702
2356 2356 a, c dbSNP:373456869
2358 2358 g, t dbSNP:371373892
2361 2361 c, t dbSNP:548923924
2363 2363 a, g dbSNP:531039633
2413 2413 a, g dbSNP:570050508
2437 2437 c, g dbSNP:1064129
2473 2473 c, t dbSNP:551991956
2474 2474 a, g dbSNP:752734160
2487 2487 a, g dbSNP:79354200
2488 2488 c, t dbSNP:746674731
2489 2489 a, g dbSNP:560119760
2567 2567 a, g dbSNP:541770238
2596 2596 -, t dbSNP:35164363
2612 2612 -, t dbSNP:537846929
2613 2613 -, g dbSNP:747281210
2613 2613 g, t dbSNP:201670618
2648 2648 c, t dbSNP:529578992
2660 2660 c, g, t dbSNP:7732895
2661 2661 a, g dbSNP:192111888
2714 2714 a, t dbSNP:143235845
2723 2723 c, t dbSNP:570833066
2724 2724 a, g dbSNP:187749277
2808 2808 c, t dbSNP:546006206
2814 2814 g, t dbSNP:755350646
2845 2845 a, g dbSNP:539753446
2869 2869 a, g dbSNP:184845639
2898 2898 a, g dbSNP:35651593
2914 2914 -, c dbSNP:34429496
2975 2975 a, c, t dbSNP:556864595
2976 2976 a, g dbSNP:567968447
2978 2978 c, t dbSNP:11952641
2980 2980 c, g dbSNP:191193183
2987 2987 a, g dbSNP:78265902
2999 2999 -, g dbSNP:34864007
3017 3017 a, g dbSNP:570166639
3036 3036 c, t dbSNP:746199208
3043 3043 a, g dbSNP:59633008
3070 3070 c, t dbSNP:113163901
3079 3079 c, t dbSNP:756627754
3125 3125 -, actgtct dbSNP:767643124
3126 3126 c, t dbSNP:187757305
3159 3159 a, c dbSNP:547971932
3160 3160 a, g dbSNP:750484768
3183 3183 a, c dbSNP:529658277
3187 3187 a, c dbSNP:562357916
3205 3205 -, aaaac dbSNP:762027741
3208 3208 -, a dbSNP:766939686
3241 3241 a, t dbSNP:78529899
3269 3269 a, g dbSNP:767524503
3313 3313 c, g dbSNP:549779315
3335 3335 c, t dbSNP:112597831
3373 3373 a, g dbSNP:182629016
3380 3380 a, c, g dbSNP:72837583
3406 3406 c, t dbSNP:34266615
3410 3410 c, t dbSNP:749346291
3441 3441 c, g dbSNP:149933620
3455 3455 c, t dbSNP:571766100
3456 3456 a, g dbSNP:79207651
3476 3476 c, t dbSNP:541622938
3477 3477 a, g dbSNP:6869490
3479 3479 c, t dbSNP:370847074
3493 3493 c, t dbSNP:556024193
3520 3520 c, t dbSNP:191256988
3544 3544 a, g dbSNP:746245033
3579 3579 c, t dbSNP:576384293
3581 3581 g, t dbSNP:769836752
3590 3590 c, t dbSNP:558100344
3603 3603 c, t dbSNP:759435022
3611 3611 c, t dbSNP:539560967
3647 3647 -, a dbSNP:750759815
3665 3665 -, c dbSNP:34655241
3681 3681 c, t dbSNP:1056039
3695 3695 a, c dbSNP:187985136
3726 3726 c, t dbSNP:548048677
3753 3753 c, t dbSNP:536039480
3758 3758 c, g dbSNP:183021002
3768 3768 c, t dbSNP:547199963
3776 3776 a, g dbSNP:531997567
3815 3815 c, t dbSNP:530134149
3816 3816 a, g dbSNP:770372502
3825 3825 c, g dbSNP:563933970
3849 3849 c, t dbSNP:10038918
3902 3902 c, t dbSNP:190785277
3920 3920 c, t dbSNP:777408020
3958 3958 c, t dbSNP:139169139
3963 3963 c, t dbSNP:559808389
3965 3965 c, t dbSNP:186399006
4006 4006 c, g, t dbSNP:574271571
4029 4029 c, t dbSNP:562677803
4068 4068 g, t dbSNP:544197979
4071 4071 a, g dbSNP:111466577
4084 4084 a, g dbSNP:73796375
4086 4086 c, g dbSNP:550889299
4103 4103 -, t dbSNP:569049701
4123 4123 g, t dbSNP:182017467
4171 4171 c, t dbSNP:539809598
4201 4201 g, t dbSNP:780436184
4287 4287 c, t dbSNP:572605070
4307 4307 c, t dbSNP:564690788
4319 4319 c, t dbSNP:554283274
4320 4320 a, g dbSNP:756959817
4339 4339 c, t dbSNP:116563155
4377 4377 c, t dbSNP:2163766
4380 4380 c, t dbSNP:550308584
4430 4430 a, c dbSNP:757808056
4439 4439 a, g dbSNP:538157761
4449 4449 a, g dbSNP:571119766
4477 4477 -, a dbSNP:376082789
4478 4478 -, a, aa dbSNP:386405298
4479 4479 -, a dbSNP:34777554
4488 4488 -, a, taataa dbSNP:138971440
4489 4489 -, taa dbSNP:147490193
4502 4502 -, aat dbSNP:57339321
4551 4551 c, t dbSNP:6882623
4603 4603 c, t dbSNP:527278402
4701 4701 g, t dbSNP:15645
4710 4710 -, t dbSNP:397724114
4717 4717 -, tttttcttttctttttt dbSNP:200240393
4720 4720 -, t dbSNP:11398735
4721 4721 -, t dbSNP:535528051
4722 4722 c, g, t dbSNP:111509060
4739 4739 a, t dbSNP:566258154
4757 4757 a, t dbSNP:192040695
4787 4787 a, g, t dbSNP:13173132
4789 4789 g, t dbSNP:6882312
4790 4790 a, g, t dbSNP:1056045
4791 4791 g, t dbSNP:7721896
4792 4792 c, g dbSNP:200391443
4793 4793 -, gc dbSNP:375452482
4794 4794 -, cgg dbSNP:199517991
4794 4794 -, cg dbSNP:138156987
4794 4794 -, c dbSNP:10609501
4794 4794 c, g dbSNP:113096177
4797 4797 -, gg dbSNP:199658748
4798 4798 -, tg dbSNP:758481941
4798 4798 -, t dbSNP:773237274
4805 4805 g, t dbSNP:565168735
4809 4809 a, g dbSNP:10038061
4812 4812 a, g dbSNP:10038060
4816 4816 a, c dbSNP:375378601
4817 4817 a, g dbSNP:114959506
4829 4829 c, t dbSNP:563147489
4834 4834 g, t dbSNP:10043606
4857 4857 a, g dbSNP:147430614

Target ORF information:

RefSeq Version NM_171825
Organism Homo sapiens (human)
Definition Homo sapiens calcium/calmodulin-dependent protein kinase II alpha (CAMK2A), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_171825

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
ATGGCCACCA TCACCTGCAC CCGCTTCACG GAAGAGTACC AGCTCTTCGA GGAATTGGGC 
AAGGGAGCCT TCTCGGTGGT GCGAAGGTGT GTGAAGGTGC TGGCTGGCCA GGAGTATGCT
GCCAAGATCA TCAACACAAA GAAGCTGTCA GCCAGAGACC ATCAGAAGCT GGAGCGTGAA
GCCCGCATCT GCCGCCTGCT GAAGCACCCC AACATCGTCC GACTACATGA CAGCATCTCA
GAGGAGGGAC ACCACTACCT GATCTTCGAC CTGGTCACTG GTGGGGAACT GTTTGAAGAT
ATCGTGGCCC GGGAGTATTA CAGTGAGGCG GATGCCAGTC ACTGTATCCA GCAGATCCTG
GAGGCTGTGC TGCACTGCCA CCAGATGGGG GTGGTGCACC GGGACCTGAA GCCTGAGAAT
CTGTTGCTGG CCTCCAAGCT CAAGGGTGCC GCAGTGAAGC TGGCAGACTT TGGCCTGGCC
ATAGAGGTGG AGGGGGAGCA GCAGGCATGG TTTGGGTTTG CAGGGACTCC TGGATATCTC
TCCCCAGAAG TGCTGCGGAA GGACCCGTAC GGGAAGCCTG TGGACCTGTG GGCTTGTGGG
GTCATCCTGT ACATCCTGCT GGTTGGGTAC CCCCCGTTCT GGGATGAGGA CCAGCACCGC
CTGTACCAGC AGATCAAAGC CGGCGCCTAT GATTTCCCAT CGCCGGAATG GGACACTGTC
ACCCCGGAAG CCAAGGATCT GATCAATAAG ATGCTGACCA TTAACCCATC CAAACGCATC
ACAGCTGCCG AAGCCCTTAA GCACCCCTGG ATCTCGCACC GCTCCACCGT GGCATCCTGC
ATGCACAGAC AGGAGACCGT GGACTGCCTG AAGAAGTTCA ATGCCAGGAG GAAACTGAAG
GGAGCCATTC TCACCACGAT GCTGGCCACC AGGAACTTCT CCGGAGGGAA GAGTGGGGGA
AACAAGAAGA GCGATGGTGT GAAGGAATCC TCAGAGAGCA CCAACACCAC CATCGAGGAT
GAAGACACCA AAGTGCGGAA ACAGGAAATT ATAAAAGTGA CAGAGCAGCT GATTGAAGCC
ATAAGCAATG GAGATTTTGA GTCCTACACG AAGATGTGCG ACCCTGGCAT GACAGCCTTC
GAACCTGAGG CCCTGGGGAA CCTGGTTGAG GGCCTGGACT TCCATCGATT CTATTTTGAA
AACCTGTGGT CCCGGAACAG CAAGCCCGTG CACACCACCA TCCTGAATCC CCACATCCAC
CTGATGGGCG ACGAGTCAGC CTGCATCGCC TACATCCGCA TCACGCAGTA CCTGGACGCT
GGCGGCATCC CACGCACCGC CCAGTCGGAG GAGACCCGTG TCTGGCACCG CCGGGATGGC
AAATGGCAGA TCGTCCACTT CCACAGATCT GGGGCGCCCT CCGTCCTGCC CCACTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

 
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