Email to GenScript

ADAMTS10 ADAM metallopeptidase with thrombospondin type 1 motif, 10 [Homo sapiens (human)]

Gene Symbol ADAMTS10
Entrez Gene ID 81794
Full Name ADAM metallopeptidase with thrombospondin type 1 motif, 10
Synonyms ADAM-TS10, ADAMTS-10, WMS, WMS1
General protein information
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

19

19p13.2

Summary This gene belongs to the ADAMTS (a disintegrin and metalloproteinase domain with thrombospondin type-1 motifs) family of zinc-dependent proteases. ADAMTS proteases are complex secreted enzymes containing a prometalloprotease domain of the reprolysin type attached to an ancillary domain with a highly conserved structure that includes at least one thrombospondin type 1 repeat. They have been demonstrated to have important roles in connective tissue organization, coagulation, inflammation, arthritis, angiogenesis and cell migration. The product of this gene plays a major role in growth and in skin, lens, and heart development. It is also a candidate gene for autosomal recessive Weill-Marchesani syndrome. [provided by RefSeq, Jul 2008]. lac of sum
Disorder MIM:

608990

Disorder Html: Weill-Marchesani syndrome, recessive, 277600 (3)





The following ADAMTS10 gene sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ADAMTS10 gene which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu72991 XM_011528331 PREDICTED: Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif, 10 (ADAMTS10), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 20 Quote Price
OHu72991 XM_011528332 PREDICTED: Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif, 10 (ADAMTS10), transcript variant X2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 20 Quote Price
OHu72991 XM_011528333 PREDICTED: Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif, 10 (ADAMTS10), transcript variant X3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 20 Quote Price
OHu72992 XM_011528334 PREDICTED: Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif, 10 (ADAMTS10), transcript variant X4, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 20 Quote Price
OHu51850 XM_006722917 PREDICTED: Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif, 10 (ADAMTS10), transcript variant X5, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 12-14 Quote Price
OHu72993 XM_011528335 PREDICTED: Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif, 10 (ADAMTS10), transcript variant X7, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 12-14 Quote Price
OHu72994 XM_011528336 PREDICTED: Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif, 10 (ADAMTS10), transcript variant X8, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 12-14 Quote Price
OHu20510 NM_030957 Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif, 10 (ADAMTS10), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 20 Quote Price
OHu20533 NM_001282352 Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif, 10 (ADAMTS10), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $439

*Business Day
**You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.


CloneID OHu72991
Accession Version XM_011528331.1
Sequence Information ORF Nucleotide Sequence (Length: 3459bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product A disintegrin and metalloproteinase with thrombospondin motifs 10 isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_011295.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
3061
3121
3181
3241
3301
3361
3421
ATGGCTCCCG CCTGCCAGAT CCTCCGCTGG GCCCTCGCCC TGGGGCTGGG CCTCATGTTC 
GAGGTCACGC ACGCCTTCCG GTCTCAAGAT GAGTTCCTGT CCAGTCTGGA GAGCTATGAG
ATCGCCTTCC CCACCCGCGT GGACCACAAC GGGGCACTGC TGGCCTTCTC GCCACCTCCT
CCCCGGAGGC AGCGCCGCGG CACGGGGGCC ACAGCCGAGT CCCGCCTCTT CTACAAAGTG
GCCTCGCCCA GCACCCACTT CCTGCTGAAC CTGACCCGCA GCTCCCGTCT ACTGGCAGGG
CACGTCTCCG TGGAGTACTG GACACGGGAG GGCCTGGCCT GGCAGAGGGC GGCCCGGCCC
CACTGCCTCT ACGCTGGTCA CCTGCAGGGC CAGGCCAGCA GCTCCCATGT GGCCATCAGC
ACCTGTGGAG GCCTGCACGG CCTGATCGTG GCAGACGAGG AAGAGTACCT GATTGAGCCC
CTGCACGGTG GGCCCAAGGG TTCTCGGAGC CCGGAGGAAA GTGGACCACA TGTGGTGTAC
AAGCGTTCCT CTCTGCGTCA CCCCCACCTG GACACAGCCT GTGGAGTGAG AGATGAGAAA
CCGTGGAAAG GGCGGCCATG GTGGCTGCGG ACCTTGAAGC CACCGCCTGC CAGGCCCCTG
GGGAATGAAA CAGAGCGTGG CCAGCCAGGC CTGAAGCGAT CGGTCAGCCG AGAGCGCTAC
GTGGAGACCC TGGTGGTGGC TGACAAGATG ATGGTGGCCT ATCACGGGCG CCGGGATGTG
GAGCAGTATG TCCTGGCCAT CATGAACATT GTTGCCAAAC TTTTCCAGGA CTCGAGTCTG
GGAAGCACCG TTAACATCCT CGTAACTCGC CTCATCCTGC TCACGGAGGA CCAGCCCACT
CTGGAGATCA CCCACCATGC CGGGAAGTCC CTGGACAGCT TCTGTAAGTG GCAGAAATCC
ATCGTGAACC ACAGCGGCCA TGGCAATGCC ATTCCAGAGA ACGGTGTGGC TAACCATGAC
ACAGCAGTGC TCATCACACG CTATGACATC TGCATCTACA AGAACAAACC CTGCGGCACA
CTAGGCCTGG CCCCGGTGGG CGGAATGTGT GAGCGCGAGA GAAGCTGCAG CGTCAATGAG
GACATTGGCC TGGCCACAGC GTTCACCATT GCCCACGAGA TCGGGCACAC ATTCGGCATG
AACCATGACG GCGTGGGAAA CAGCTGTGGG GCCCGTGGTC AGGACCCAGC CAAGCTCATG
GCTGCCCACA TTACCATGAA GACCAACCCA TTCGTGTGGT CATCCTGCAG CCGTGACTAC
ATCACCAGCT TTCTAGACTC GGGCCTGGGG CTCTGCCTGA ACAACCGGCC CCCCAGACAG
GACTTTGTGT ACCCGACAGT GGCACCGGGC CAAGCCTACG ATGCAGATGA GCAATGCCGC
TTTCAGCATG GAGTCAAATC GCGTCAGTGT AAATACGGGG AGGTCTGCAG CGAGCTGTGG
TGTCTGAGCA AGAGCAACCG GTGCATCACC AACAGCATCC CGGCCGCCGA GGGCACGCTG
TGCCAGACGC ACACCATCGA CAAGGGGTGG TGCTACAAAC GGGTCTGTGT CCCCTTTGGG
TCGCGCCCAG AGGGTGTGGA CGGAGCCTGG GGGCCGTGGA CTCCATGGGG CGACTGCAGC
CGGACCTGTG GCGGCGGCGT GTCCTCTTCT AGCCGTCACT GCGACAGCCC CAGGCCAACC
ATCGGGGGCA AGTACTGTCT GGGTGAGAGA AGGCGGCACC GCTCCTGCAA CACGGATGAC
TGTCCCCCTG GCTCCCAGGA CTTCAGAGAA GTGCAGTGTT CTGAATTTGA CAGCATCCCT
TTCCGTGGGA AATTCTACAA GTGGAAAACG TACCGGGGAG GGGGCGTGAA GGCCTGCTCG
CTCACGTGCC TAGCGGAAGG CTTCAACTTC TACACGGAGA GGGCGGCAGC CGTGGTGGAC
GGGACACCCT GCCGTCCAGA CACGGTGGAC ATTTGCGTCA GTGGCGAATG CAAGCACGTG
GGCTGCGACC GAGTCCTGGG CTCCGACCTG CGGGAGGACA AGTGCCGAGT GTGTGGCGGT
GACGGCAGTG CCTGCGAGAC CATCGAGGGC GTCTTCAGCC CAGCCTCACC TGGGGCCGGG
TACGAGGATG TCGTCTGGAT TCCCAAAGGC TCCGTCCACA TCTTCATCCA GGATCTGAAC
CTCTCTCTCA GTCACTTGGC CCTGAAGGGA GACCAGGAGT CCCTGCTGCT GGAGGGGCTG
CCTGGGACCC CCCAGCCCCA CCGTCTGCCT CTAGCTGGGA CCACCTTTCA ACTGCGACAG
GGGCCAGACC AGGTCCAGAG CCTCGAAGCC CTGGGACCGA TTAATGCATC TCTCATCGTC
ATGGTGCTGG CCCGGACCGA GCTGCCTGCC CTCCGCTACC GCTTCAATGC CCCCATCGCC
CGTGACTCGC TGCCCCCCTA CTCCTGGCAC TATGCGCCCT GGACCAAGTG CTCGGCCCAG
TGTGCAGGCG GTAGCCAGGT GCAGGCGGTG GAGTGCCGCA ACCAGCTGGA CAGCTCCGCG
GTCGCCCCCC ACTACTGCAG TGCCCACAGC AAGCTGCCCA AAAGGCAGCG CGCCTGCAAC
ACGGAGCCTT GCCCTCCAGA CTGGGTTGTA GGGAACTGGT CGCTCTGCAG CCGCAGCTGC
GATGCAGGCG TGCGCAGCCG CTCGGTCGTG TGCCAGCGCC GCGTCTCTGC CGCGGAGGAG
AAGGCGCTGG ACGACAGCGC ATGCCCGCAG CCGCGCCCAC CTGTACTGGA GGCCTGCCAC
GGCCCCACTT GCCCTCCGGA GTGGGCGGCC CTCGACTGGT CTGAGGTCAG CCGCCCCCTT
CCTTCGCGCC CACTGGGATG CCCAGGTGGG GTGTCCACGG AGACGCCTCT GCGCGGTCTC
CAGGTTAGCT GTCCCCTCCT CACTTCGCAC TGGGGCAGCA CCCTGAGCAC GAAACGCCCC
TTCCAACTGC AGTGCACCCC CAGCTGCGGG CCGGGCCTCC GCCACCGCGT GGTCCTTTGC
AAGAGCGCAG ACCACCGCGC CACGCTGCCC CCGGCGCACT GCTCACCCGC CGCCAAGCCA
CCGGCCACCA TGCGCTGCAA CTTGCGCCGC TGCCCCCCGG CCCGCTGGGT GGCTGGCGAG
TGGGGTGAGT GCTCTGCACA GTGCGGCGTC GGGCAGCGGC AGCGCTCGGT GCGCTGCACC
AGCCACACGG GCCAGGCGTC GCACGAGTGC ACGGAGGCCC TGCGGCCGCC CACCACGCAG
CAGTGTGAGG CCAAGTGCGA CAGCCCAACC CCCGGGGACG GCCCTGAAGA GTGCAAGGAT
GTGAACAAGG TCGCCTACTG CCCCCTGGTG CTCAAATTTC AGTTCTGCAG CCGAGCCTAC
TTCCGCCAGA TGTGCTGCAA AACCTGCCAT GGCCACTAG
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqXP_011526633.1
CDS278..3736
Misc Feature(1)392..817(+)
Misc Feature(2)992..1648(+)
Misc Feature(3)992..1639(+)
Misc Feature(4)1451..1483(+)
Misc Feature(5)1925..2083(+)
Misc Feature(6)2393..2731(+)
Misc Feature(7)2762..2932(+)
Misc Feature(8)3452..3586(+)
Misc Feature(9)3626..3724(+)
Translation
Position Chain Variation Link
350 350 a, g dbSNP:121434358
356 356 a, c, t dbSNP:111234410
633 633 a, c, g dbSNP:3814291
678 678 c, g dbSNP:7255721
986 986 c, t dbSNP:121434357
1045 1045 g, t dbSNP:200589780
1055 1055 a, g dbSNP:756947226
1229 1229 c, t dbSNP:121434359
1275 1275 a, c dbSNP:775640275
1337 1337 a, g dbSNP:759348240
1830 1830 a, g dbSNP:267606636
2213 2213 a, g dbSNP:148605664
2242 2242 a, g dbSNP:113579886
2246 2246 a, g dbSNP:202232012
2375 2375 a, g, t dbSNP:267606637
3617 3617 a, g dbSNP:80046653
3727 3727 g, t dbSNP:7252299
4058 4058 -, c dbSNP:150352175
4070 4070 g, t dbSNP:745911505
4183 4183 -, g dbSNP:527806324

Target ORF information:

RefSeq Version XM_011528331
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif, 10 (ADAMTS10), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011528331

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
3061
3121
3181
3241
3301
3361
3421
ATGGCTCCCG CCTGCCAGAT CCTCCGCTGG GCCCTCGCCC TGGGGCTGGG CCTCATGTTC 
GAGGTCACGC ACGCCTTCCG GTCTCAAGAT GAGTTCCTGT CCAGTCTGGA GAGCTATGAG
ATCGCCTTCC CCACCCGCGT GGACCACAAC GGGGCACTGC TGGCCTTCTC GCCACCTCCT
CCCCGGAGGC AGCGCCGCGG CACGGGGGCC ACAGCCGAGT CCCGCCTCTT CTACAAAGTG
GCCTCGCCCA GCACCCACTT CCTGCTGAAC CTGACCCGCA GCTCCCGTCT ACTGGCAGGG
CACGTCTCCG TGGAGTACTG GACACGGGAG GGCCTGGCCT GGCAGAGGGC GGCCCGGCCC
CACTGCCTCT ACGCTGGTCA CCTGCAGGGC CAGGCCAGCA GCTCCCATGT GGCCATCAGC
ACCTGTGGAG GCCTGCACGG CCTGATCGTG GCAGACGAGG AAGAGTACCT GATTGAGCCC
CTGCACGGTG GGCCCAAGGG TTCTCGGAGC CCGGAGGAAA GTGGACCACA TGTGGTGTAC
AAGCGTTCCT CTCTGCGTCA CCCCCACCTG GACACAGCCT GTGGAGTGAG AGATGAGAAA
CCGTGGAAAG GGCGGCCATG GTGGCTGCGG ACCTTGAAGC CACCGCCTGC CAGGCCCCTG
GGGAATGAAA CAGAGCGTGG CCAGCCAGGC CTGAAGCGAT CGGTCAGCCG AGAGCGCTAC
GTGGAGACCC TGGTGGTGGC TGACAAGATG ATGGTGGCCT ATCACGGGCG CCGGGATGTG
GAGCAGTATG TCCTGGCCAT CATGAACATT GTTGCCAAAC TTTTCCAGGA CTCGAGTCTG
GGAAGCACCG TTAACATCCT CGTAACTCGC CTCATCCTGC TCACGGAGGA CCAGCCCACT
CTGGAGATCA CCCACCATGC CGGGAAGTCC CTGGACAGCT TCTGTAAGTG GCAGAAATCC
ATCGTGAACC ACAGCGGCCA TGGCAATGCC ATTCCAGAGA ACGGTGTGGC TAACCATGAC
ACAGCAGTGC TCATCACACG CTATGACATC TGCATCTACA AGAACAAACC CTGCGGCACA
CTAGGCCTGG CCCCGGTGGG CGGAATGTGT GAGCGCGAGA GAAGCTGCAG CGTCAATGAG
GACATTGGCC TGGCCACAGC GTTCACCATT GCCCACGAGA TCGGGCACAC ATTCGGCATG
AACCATGACG GCGTGGGAAA CAGCTGTGGG GCCCGTGGTC AGGACCCAGC CAAGCTCATG
GCTGCCCACA TTACCATGAA GACCAACCCA TTCGTGTGGT CATCCTGCAG CCGTGACTAC
ATCACCAGCT TTCTAGACTC GGGCCTGGGG CTCTGCCTGA ACAACCGGCC CCCCAGACAG
GACTTTGTGT ACCCGACAGT GGCACCGGGC CAAGCCTACG ATGCAGATGA GCAATGCCGC
TTTCAGCATG GAGTCAAATC GCGTCAGTGT AAATACGGGG AGGTCTGCAG CGAGCTGTGG
TGTCTGAGCA AGAGCAACCG GTGCATCACC AACAGCATCC CGGCCGCCGA GGGCACGCTG
TGCCAGACGC ACACCATCGA CAAGGGGTGG TGCTACAAAC GGGTCTGTGT CCCCTTTGGG
TCGCGCCCAG AGGGTGTGGA CGGAGCCTGG GGGCCGTGGA CTCCATGGGG CGACTGCAGC
CGGACCTGTG GCGGCGGCGT GTCCTCTTCT AGCCGTCACT GCGACAGCCC CAGGCCAACC
ATCGGGGGCA AGTACTGTCT GGGTGAGAGA AGGCGGCACC GCTCCTGCAA CACGGATGAC
TGTCCCCCTG GCTCCCAGGA CTTCAGAGAA GTGCAGTGTT CTGAATTTGA CAGCATCCCT
TTCCGTGGGA AATTCTACAA GTGGAAAACG TACCGGGGAG GGGGCGTGAA GGCCTGCTCG
CTCACGTGCC TAGCGGAAGG CTTCAACTTC TACACGGAGA GGGCGGCAGC CGTGGTGGAC
GGGACACCCT GCCGTCCAGA CACGGTGGAC ATTTGCGTCA GTGGCGAATG CAAGCACGTG
GGCTGCGACC GAGTCCTGGG CTCCGACCTG CGGGAGGACA AGTGCCGAGT GTGTGGCGGT
GACGGCAGTG CCTGCGAGAC CATCGAGGGC GTCTTCAGCC CAGCCTCACC TGGGGCCGGG
TACGAGGATG TCGTCTGGAT TCCCAAAGGC TCCGTCCACA TCTTCATCCA GGATCTGAAC
CTCTCTCTCA GTCACTTGGC CCTGAAGGGA GACCAGGAGT CCCTGCTGCT GGAGGGGCTG
CCTGGGACCC CCCAGCCCCA CCGTCTGCCT CTAGCTGGGA CCACCTTTCA ACTGCGACAG
GGGCCAGACC AGGTCCAGAG CCTCGAAGCC CTGGGACCGA TTAATGCATC TCTCATCGTC
ATGGTGCTGG CCCGGACCGA GCTGCCTGCC CTCCGCTACC GCTTCAATGC CCCCATCGCC
CGTGACTCGC TGCCCCCCTA CTCCTGGCAC TATGCGCCCT GGACCAAGTG CTCGGCCCAG
TGTGCAGGCG GTAGCCAGGT GCAGGCGGTG GAGTGCCGCA ACCAGCTGGA CAGCTCCGCG
GTCGCCCCCC ACTACTGCAG TGCCCACAGC AAGCTGCCCA AAAGGCAGCG CGCCTGCAAC
ACGGAGCCTT GCCCTCCAGA CTGGGTTGTA GGGAACTGGT CGCTCTGCAG CCGCAGCTGC
GATGCAGGCG TGCGCAGCCG CTCGGTCGTG TGCCAGCGCC GCGTCTCTGC CGCGGAGGAG
AAGGCGCTGG ACGACAGCGC ATGCCCGCAG CCGCGCCCAC CTGTACTGGA GGCCTGCCAC
GGCCCCACTT GCCCTCCGGA GTGGGCGGCC CTCGACTGGT CTGAGGTCAG CCGCCCCCTT
CCTTCGCGCC CACTGGGATG CCCAGGTGGG GTGTCCACGG AGACGCCTCT GCGCGGTCTC
CAGGTTAGCT GTCCCCTCCT CACTTCGCAC TGGGGCAGCA CCCTGAGCAC GAAACGCCCC
TTCCAACTGC AGTGCACCCC CAGCTGCGGG CCGGGCCTCC GCCACCGCGT GGTCCTTTGC
AAGAGCGCAG ACCACCGCGC CACGCTGCCC CCGGCGCACT GCTCACCCGC CGCCAAGCCA
CCGGCCACCA TGCGCTGCAA CTTGCGCCGC TGCCCCCCGG CCCGCTGGGT GGCTGGCGAG
TGGGGTGAGT GCTCTGCACA GTGCGGCGTC GGGCAGCGGC AGCGCTCGGT GCGCTGCACC
AGCCACACGG GCCAGGCGTC GCACGAGTGC ACGGAGGCCC TGCGGCCGCC CACCACGCAG
CAGTGTGAGG CCAAGTGCGA CAGCCCAACC CCCGGGGACG GCCCTGAAGA GTGCAAGGAT
GTGAACAAGG TCGCCTACTG CCCCCTGGTG CTCAAATTTC AGTTCTGCAG CCGAGCCTAC
TTCCGCCAGA TGTGCTGCAA AACCTGCCAT GGCCACTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu72991
Accession Version XM_011528332.1
Sequence Information ORF Nucleotide Sequence (Length: 3459bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product A disintegrin and metalloproteinase with thrombospondin motifs 10 isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_011295.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
3061
3121
3181
3241
3301
3361
3421
ATGGCTCCCG CCTGCCAGAT CCTCCGCTGG GCCCTCGCCC TGGGGCTGGG CCTCATGTTC 
GAGGTCACGC ACGCCTTCCG GTCTCAAGAT GAGTTCCTGT CCAGTCTGGA GAGCTATGAG
ATCGCCTTCC CCACCCGCGT GGACCACAAC GGGGCACTGC TGGCCTTCTC GCCACCTCCT
CCCCGGAGGC AGCGCCGCGG CACGGGGGCC ACAGCCGAGT CCCGCCTCTT CTACAAAGTG
GCCTCGCCCA GCACCCACTT CCTGCTGAAC CTGACCCGCA GCTCCCGTCT ACTGGCAGGG
CACGTCTCCG TGGAGTACTG GACACGGGAG GGCCTGGCCT GGCAGAGGGC GGCCCGGCCC
CACTGCCTCT ACGCTGGTCA CCTGCAGGGC CAGGCCAGCA GCTCCCATGT GGCCATCAGC
ACCTGTGGAG GCCTGCACGG CCTGATCGTG GCAGACGAGG AAGAGTACCT GATTGAGCCC
CTGCACGGTG GGCCCAAGGG TTCTCGGAGC CCGGAGGAAA GTGGACCACA TGTGGTGTAC
AAGCGTTCCT CTCTGCGTCA CCCCCACCTG GACACAGCCT GTGGAGTGAG AGATGAGAAA
CCGTGGAAAG GGCGGCCATG GTGGCTGCGG ACCTTGAAGC CACCGCCTGC CAGGCCCCTG
GGGAATGAAA CAGAGCGTGG CCAGCCAGGC CTGAAGCGAT CGGTCAGCCG AGAGCGCTAC
GTGGAGACCC TGGTGGTGGC TGACAAGATG ATGGTGGCCT ATCACGGGCG CCGGGATGTG
GAGCAGTATG TCCTGGCCAT CATGAACATT GTTGCCAAAC TTTTCCAGGA CTCGAGTCTG
GGAAGCACCG TTAACATCCT CGTAACTCGC CTCATCCTGC TCACGGAGGA CCAGCCCACT
CTGGAGATCA CCCACCATGC CGGGAAGTCC CTGGACAGCT TCTGTAAGTG GCAGAAATCC
ATCGTGAACC ACAGCGGCCA TGGCAATGCC ATTCCAGAGA ACGGTGTGGC TAACCATGAC
ACAGCAGTGC TCATCACACG CTATGACATC TGCATCTACA AGAACAAACC CTGCGGCACA
CTAGGCCTGG CCCCGGTGGG CGGAATGTGT GAGCGCGAGA GAAGCTGCAG CGTCAATGAG
GACATTGGCC TGGCCACAGC GTTCACCATT GCCCACGAGA TCGGGCACAC ATTCGGCATG
AACCATGACG GCGTGGGAAA CAGCTGTGGG GCCCGTGGTC AGGACCCAGC CAAGCTCATG
GCTGCCCACA TTACCATGAA GACCAACCCA TTCGTGTGGT CATCCTGCAG CCGTGACTAC
ATCACCAGCT TTCTAGACTC GGGCCTGGGG CTCTGCCTGA ACAACCGGCC CCCCAGACAG
GACTTTGTGT ACCCGACAGT GGCACCGGGC CAAGCCTACG ATGCAGATGA GCAATGCCGC
TTTCAGCATG GAGTCAAATC GCGTCAGTGT AAATACGGGG AGGTCTGCAG CGAGCTGTGG
TGTCTGAGCA AGAGCAACCG GTGCATCACC AACAGCATCC CGGCCGCCGA GGGCACGCTG
TGCCAGACGC ACACCATCGA CAAGGGGTGG TGCTACAAAC GGGTCTGTGT CCCCTTTGGG
TCGCGCCCAG AGGGTGTGGA CGGAGCCTGG GGGCCGTGGA CTCCATGGGG CGACTGCAGC
CGGACCTGTG GCGGCGGCGT GTCCTCTTCT AGCCGTCACT GCGACAGCCC CAGGCCAACC
ATCGGGGGCA AGTACTGTCT GGGTGAGAGA AGGCGGCACC GCTCCTGCAA CACGGATGAC
TGTCCCCCTG GCTCCCAGGA CTTCAGAGAA GTGCAGTGTT CTGAATTTGA CAGCATCCCT
TTCCGTGGGA AATTCTACAA GTGGAAAACG TACCGGGGAG GGGGCGTGAA GGCCTGCTCG
CTCACGTGCC TAGCGGAAGG CTTCAACTTC TACACGGAGA GGGCGGCAGC CGTGGTGGAC
GGGACACCCT GCCGTCCAGA CACGGTGGAC ATTTGCGTCA GTGGCGAATG CAAGCACGTG
GGCTGCGACC GAGTCCTGGG CTCCGACCTG CGGGAGGACA AGTGCCGAGT GTGTGGCGGT
GACGGCAGTG CCTGCGAGAC CATCGAGGGC GTCTTCAGCC CAGCCTCACC TGGGGCCGGG
TACGAGGATG TCGTCTGGAT TCCCAAAGGC TCCGTCCACA TCTTCATCCA GGATCTGAAC
CTCTCTCTCA GTCACTTGGC CCTGAAGGGA GACCAGGAGT CCCTGCTGCT GGAGGGGCTG
CCTGGGACCC CCCAGCCCCA CCGTCTGCCT CTAGCTGGGA CCACCTTTCA ACTGCGACAG
GGGCCAGACC AGGTCCAGAG CCTCGAAGCC CTGGGACCGA TTAATGCATC TCTCATCGTC
ATGGTGCTGG CCCGGACCGA GCTGCCTGCC CTCCGCTACC GCTTCAATGC CCCCATCGCC
CGTGACTCGC TGCCCCCCTA CTCCTGGCAC TATGCGCCCT GGACCAAGTG CTCGGCCCAG
TGTGCAGGCG GTAGCCAGGT GCAGGCGGTG GAGTGCCGCA ACCAGCTGGA CAGCTCCGCG
GTCGCCCCCC ACTACTGCAG TGCCCACAGC AAGCTGCCCA AAAGGCAGCG CGCCTGCAAC
ACGGAGCCTT GCCCTCCAGA CTGGGTTGTA GGGAACTGGT CGCTCTGCAG CCGCAGCTGC
GATGCAGGCG TGCGCAGCCG CTCGGTCGTG TGCCAGCGCC GCGTCTCTGC CGCGGAGGAG
AAGGCGCTGG ACGACAGCGC ATGCCCGCAG CCGCGCCCAC CTGTACTGGA GGCCTGCCAC
GGCCCCACTT GCCCTCCGGA GTGGGCGGCC CTCGACTGGT CTGAGGTCAG CCGCCCCCTT
CCTTCGCGCC CACTGGGATG CCCAGGTGGG GTGTCCACGG AGACGCCTCT GCGCGGTCTC
CAGGTTAGCT GTCCCCTCCT CACTTCGCAC TGGGGCAGCA CCCTGAGCAC GAAACGCCCC
TTCCAACTGC AGTGCACCCC CAGCTGCGGG CCGGGCCTCC GCCACCGCGT GGTCCTTTGC
AAGAGCGCAG ACCACCGCGC CACGCTGCCC CCGGCGCACT GCTCACCCGC CGCCAAGCCA
CCGGCCACCA TGCGCTGCAA CTTGCGCCGC TGCCCCCCGG CCCGCTGGGT GGCTGGCGAG
TGGGGTGAGT GCTCTGCACA GTGCGGCGTC GGGCAGCGGC AGCGCTCGGT GCGCTGCACC
AGCCACACGG GCCAGGCGTC GCACGAGTGC ACGGAGGCCC TGCGGCCGCC CACCACGCAG
CAGTGTGAGG CCAAGTGCGA CAGCCCAACC CCCGGGGACG GCCCTGAAGA GTGCAAGGAT
GTGAACAAGG TCGCCTACTG CCCCCTGGTG CTCAAATTTC AGTTCTGCAG CCGAGCCTAC
TTCCGCCAGA TGTGCTGCAA AACCTGCCAT GGCCACTAG
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqXP_011526634.1
CDS1882..5340
Misc Feature(1)1996..2421(+)
Misc Feature(2)2596..3252(+)
Misc Feature(3)2596..3243(+)
Misc Feature(4)3055..3087(+)
Misc Feature(5)3529..3687(+)
Misc Feature(6)3997..4335(+)
Misc Feature(7)4366..4536(+)
Misc Feature(8)5056..5190(+)
Misc Feature(9)5230..5328(+)
Translation
Position Chain Variation Link
48 48 a, g dbSNP:763884862
324 324 c, g dbSNP:12462074
357 357 -, gt dbSNP:374652955
886 886 a, c dbSNP:112914127
914 914 a, g dbSNP:78127325
1124 1124 c, g dbSNP:773946163
1318 1318 -, ca, caca dbSNP:35269308
1400 1400 a, c dbSNP:73501596
1551 1551 c, t dbSNP:10401300
1577 1577 a, g dbSNP:79928909
1662 1662 a, g dbSNP:79056476
1664 1664 a, g dbSNP:7507292
1954 1954 a, g dbSNP:121434358
1960 1960 a, c, t dbSNP:111234410
2237 2237 a, c, g dbSNP:3814291
2282 2282 c, g dbSNP:7255721
2590 2590 c, t dbSNP:121434357
2649 2649 g, t dbSNP:200589780
2659 2659 a, g dbSNP:756947226
2833 2833 c, t dbSNP:121434359
2879 2879 a, c dbSNP:775640275
2941 2941 a, g dbSNP:759348240
3434 3434 a, g dbSNP:267606636
3817 3817 a, g dbSNP:148605664
3846 3846 a, g dbSNP:113579886
3850 3850 a, g dbSNP:202232012
3979 3979 a, g, t dbSNP:267606637
5221 5221 a, g dbSNP:80046653
5331 5331 g, t dbSNP:7252299
5662 5662 -, c dbSNP:150352175
5674 5674 g, t dbSNP:745911505
5787 5787 -, g dbSNP:527806324

Target ORF information:

RefSeq Version XM_011528332
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif, 10 (ADAMTS10), transcript variant X2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011528332

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
3061
3121
3181
3241
3301
3361
3421
ATGGCTCCCG CCTGCCAGAT CCTCCGCTGG GCCCTCGCCC TGGGGCTGGG CCTCATGTTC 
GAGGTCACGC ACGCCTTCCG GTCTCAAGAT GAGTTCCTGT CCAGTCTGGA GAGCTATGAG
ATCGCCTTCC CCACCCGCGT GGACCACAAC GGGGCACTGC TGGCCTTCTC GCCACCTCCT
CCCCGGAGGC AGCGCCGCGG CACGGGGGCC ACAGCCGAGT CCCGCCTCTT CTACAAAGTG
GCCTCGCCCA GCACCCACTT CCTGCTGAAC CTGACCCGCA GCTCCCGTCT ACTGGCAGGG
CACGTCTCCG TGGAGTACTG GACACGGGAG GGCCTGGCCT GGCAGAGGGC GGCCCGGCCC
CACTGCCTCT ACGCTGGTCA CCTGCAGGGC CAGGCCAGCA GCTCCCATGT GGCCATCAGC
ACCTGTGGAG GCCTGCACGG CCTGATCGTG GCAGACGAGG AAGAGTACCT GATTGAGCCC
CTGCACGGTG GGCCCAAGGG TTCTCGGAGC CCGGAGGAAA GTGGACCACA TGTGGTGTAC
AAGCGTTCCT CTCTGCGTCA CCCCCACCTG GACACAGCCT GTGGAGTGAG AGATGAGAAA
CCGTGGAAAG GGCGGCCATG GTGGCTGCGG ACCTTGAAGC CACCGCCTGC CAGGCCCCTG
GGGAATGAAA CAGAGCGTGG CCAGCCAGGC CTGAAGCGAT CGGTCAGCCG AGAGCGCTAC
GTGGAGACCC TGGTGGTGGC TGACAAGATG ATGGTGGCCT ATCACGGGCG CCGGGATGTG
GAGCAGTATG TCCTGGCCAT CATGAACATT GTTGCCAAAC TTTTCCAGGA CTCGAGTCTG
GGAAGCACCG TTAACATCCT CGTAACTCGC CTCATCCTGC TCACGGAGGA CCAGCCCACT
CTGGAGATCA CCCACCATGC CGGGAAGTCC CTGGACAGCT TCTGTAAGTG GCAGAAATCC
ATCGTGAACC ACAGCGGCCA TGGCAATGCC ATTCCAGAGA ACGGTGTGGC TAACCATGAC
ACAGCAGTGC TCATCACACG CTATGACATC TGCATCTACA AGAACAAACC CTGCGGCACA
CTAGGCCTGG CCCCGGTGGG CGGAATGTGT GAGCGCGAGA GAAGCTGCAG CGTCAATGAG
GACATTGGCC TGGCCACAGC GTTCACCATT GCCCACGAGA TCGGGCACAC ATTCGGCATG
AACCATGACG GCGTGGGAAA CAGCTGTGGG GCCCGTGGTC AGGACCCAGC CAAGCTCATG
GCTGCCCACA TTACCATGAA GACCAACCCA TTCGTGTGGT CATCCTGCAG CCGTGACTAC
ATCACCAGCT TTCTAGACTC GGGCCTGGGG CTCTGCCTGA ACAACCGGCC CCCCAGACAG
GACTTTGTGT ACCCGACAGT GGCACCGGGC CAAGCCTACG ATGCAGATGA GCAATGCCGC
TTTCAGCATG GAGTCAAATC GCGTCAGTGT AAATACGGGG AGGTCTGCAG CGAGCTGTGG
TGTCTGAGCA AGAGCAACCG GTGCATCACC AACAGCATCC CGGCCGCCGA GGGCACGCTG
TGCCAGACGC ACACCATCGA CAAGGGGTGG TGCTACAAAC GGGTCTGTGT CCCCTTTGGG
TCGCGCCCAG AGGGTGTGGA CGGAGCCTGG GGGCCGTGGA CTCCATGGGG CGACTGCAGC
CGGACCTGTG GCGGCGGCGT GTCCTCTTCT AGCCGTCACT GCGACAGCCC CAGGCCAACC
ATCGGGGGCA AGTACTGTCT GGGTGAGAGA AGGCGGCACC GCTCCTGCAA CACGGATGAC
TGTCCCCCTG GCTCCCAGGA CTTCAGAGAA GTGCAGTGTT CTGAATTTGA CAGCATCCCT
TTCCGTGGGA AATTCTACAA GTGGAAAACG TACCGGGGAG GGGGCGTGAA GGCCTGCTCG
CTCACGTGCC TAGCGGAAGG CTTCAACTTC TACACGGAGA GGGCGGCAGC CGTGGTGGAC
GGGACACCCT GCCGTCCAGA CACGGTGGAC ATTTGCGTCA GTGGCGAATG CAAGCACGTG
GGCTGCGACC GAGTCCTGGG CTCCGACCTG CGGGAGGACA AGTGCCGAGT GTGTGGCGGT
GACGGCAGTG CCTGCGAGAC CATCGAGGGC GTCTTCAGCC CAGCCTCACC TGGGGCCGGG
TACGAGGATG TCGTCTGGAT TCCCAAAGGC TCCGTCCACA TCTTCATCCA GGATCTGAAC
CTCTCTCTCA GTCACTTGGC CCTGAAGGGA GACCAGGAGT CCCTGCTGCT GGAGGGGCTG
CCTGGGACCC CCCAGCCCCA CCGTCTGCCT CTAGCTGGGA CCACCTTTCA ACTGCGACAG
GGGCCAGACC AGGTCCAGAG CCTCGAAGCC CTGGGACCGA TTAATGCATC TCTCATCGTC
ATGGTGCTGG CCCGGACCGA GCTGCCTGCC CTCCGCTACC GCTTCAATGC CCCCATCGCC
CGTGACTCGC TGCCCCCCTA CTCCTGGCAC TATGCGCCCT GGACCAAGTG CTCGGCCCAG
TGTGCAGGCG GTAGCCAGGT GCAGGCGGTG GAGTGCCGCA ACCAGCTGGA CAGCTCCGCG
GTCGCCCCCC ACTACTGCAG TGCCCACAGC AAGCTGCCCA AAAGGCAGCG CGCCTGCAAC
ACGGAGCCTT GCCCTCCAGA CTGGGTTGTA GGGAACTGGT CGCTCTGCAG CCGCAGCTGC
GATGCAGGCG TGCGCAGCCG CTCGGTCGTG TGCCAGCGCC GCGTCTCTGC CGCGGAGGAG
AAGGCGCTGG ACGACAGCGC ATGCCCGCAG CCGCGCCCAC CTGTACTGGA GGCCTGCCAC
GGCCCCACTT GCCCTCCGGA GTGGGCGGCC CTCGACTGGT CTGAGGTCAG CCGCCCCCTT
CCTTCGCGCC CACTGGGATG CCCAGGTGGG GTGTCCACGG AGACGCCTCT GCGCGGTCTC
CAGGTTAGCT GTCCCCTCCT CACTTCGCAC TGGGGCAGCA CCCTGAGCAC GAAACGCCCC
TTCCAACTGC AGTGCACCCC CAGCTGCGGG CCGGGCCTCC GCCACCGCGT GGTCCTTTGC
AAGAGCGCAG ACCACCGCGC CACGCTGCCC CCGGCGCACT GCTCACCCGC CGCCAAGCCA
CCGGCCACCA TGCGCTGCAA CTTGCGCCGC TGCCCCCCGG CCCGCTGGGT GGCTGGCGAG
TGGGGTGAGT GCTCTGCACA GTGCGGCGTC GGGCAGCGGC AGCGCTCGGT GCGCTGCACC
AGCCACACGG GCCAGGCGTC GCACGAGTGC ACGGAGGCCC TGCGGCCGCC CACCACGCAG
CAGTGTGAGG CCAAGTGCGA CAGCCCAACC CCCGGGGACG GCCCTGAAGA GTGCAAGGAT
GTGAACAAGG TCGCCTACTG CCCCCTGGTG CTCAAATTTC AGTTCTGCAG CCGAGCCTAC
TTCCGCCAGA TGTGCTGCAA AACCTGCCAT GGCCACTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu72991
Accession Version XM_011528333.1
Sequence Information ORF Nucleotide Sequence (Length: 3459bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product A disintegrin and metalloproteinase with thrombospondin motifs 10 isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_011295.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
3061
3121
3181
3241
3301
3361
3421
ATGGCTCCCG CCTGCCAGAT CCTCCGCTGG GCCCTCGCCC TGGGGCTGGG CCTCATGTTC 
GAGGTCACGC ACGCCTTCCG GTCTCAAGAT GAGTTCCTGT CCAGTCTGGA GAGCTATGAG
ATCGCCTTCC CCACCCGCGT GGACCACAAC GGGGCACTGC TGGCCTTCTC GCCACCTCCT
CCCCGGAGGC AGCGCCGCGG CACGGGGGCC ACAGCCGAGT CCCGCCTCTT CTACAAAGTG
GCCTCGCCCA GCACCCACTT CCTGCTGAAC CTGACCCGCA GCTCCCGTCT ACTGGCAGGG
CACGTCTCCG TGGAGTACTG GACACGGGAG GGCCTGGCCT GGCAGAGGGC GGCCCGGCCC
CACTGCCTCT ACGCTGGTCA CCTGCAGGGC CAGGCCAGCA GCTCCCATGT GGCCATCAGC
ACCTGTGGAG GCCTGCACGG CCTGATCGTG GCAGACGAGG AAGAGTACCT GATTGAGCCC
CTGCACGGTG GGCCCAAGGG TTCTCGGAGC CCGGAGGAAA GTGGACCACA TGTGGTGTAC
AAGCGTTCCT CTCTGCGTCA CCCCCACCTG GACACAGCCT GTGGAGTGAG AGATGAGAAA
CCGTGGAAAG GGCGGCCATG GTGGCTGCGG ACCTTGAAGC CACCGCCTGC CAGGCCCCTG
GGGAATGAAA CAGAGCGTGG CCAGCCAGGC CTGAAGCGAT CGGTCAGCCG AGAGCGCTAC
GTGGAGACCC TGGTGGTGGC TGACAAGATG ATGGTGGCCT ATCACGGGCG CCGGGATGTG
GAGCAGTATG TCCTGGCCAT CATGAACATT GTTGCCAAAC TTTTCCAGGA CTCGAGTCTG
GGAAGCACCG TTAACATCCT CGTAACTCGC CTCATCCTGC TCACGGAGGA CCAGCCCACT
CTGGAGATCA CCCACCATGC CGGGAAGTCC CTGGACAGCT TCTGTAAGTG GCAGAAATCC
ATCGTGAACC ACAGCGGCCA TGGCAATGCC ATTCCAGAGA ACGGTGTGGC TAACCATGAC
ACAGCAGTGC TCATCACACG CTATGACATC TGCATCTACA AGAACAAACC CTGCGGCACA
CTAGGCCTGG CCCCGGTGGG CGGAATGTGT GAGCGCGAGA GAAGCTGCAG CGTCAATGAG
GACATTGGCC TGGCCACAGC GTTCACCATT GCCCACGAGA TCGGGCACAC ATTCGGCATG
AACCATGACG GCGTGGGAAA CAGCTGTGGG GCCCGTGGTC AGGACCCAGC CAAGCTCATG
GCTGCCCACA TTACCATGAA GACCAACCCA TTCGTGTGGT CATCCTGCAG CCGTGACTAC
ATCACCAGCT TTCTAGACTC GGGCCTGGGG CTCTGCCTGA ACAACCGGCC CCCCAGACAG
GACTTTGTGT ACCCGACAGT GGCACCGGGC CAAGCCTACG ATGCAGATGA GCAATGCCGC
TTTCAGCATG GAGTCAAATC GCGTCAGTGT AAATACGGGG AGGTCTGCAG CGAGCTGTGG
TGTCTGAGCA AGAGCAACCG GTGCATCACC AACAGCATCC CGGCCGCCGA GGGCACGCTG
TGCCAGACGC ACACCATCGA CAAGGGGTGG TGCTACAAAC GGGTCTGTGT CCCCTTTGGG
TCGCGCCCAG AGGGTGTGGA CGGAGCCTGG GGGCCGTGGA CTCCATGGGG CGACTGCAGC
CGGACCTGTG GCGGCGGCGT GTCCTCTTCT AGCCGTCACT GCGACAGCCC CAGGCCAACC
ATCGGGGGCA AGTACTGTCT GGGTGAGAGA AGGCGGCACC GCTCCTGCAA CACGGATGAC
TGTCCCCCTG GCTCCCAGGA CTTCAGAGAA GTGCAGTGTT CTGAATTTGA CAGCATCCCT
TTCCGTGGGA AATTCTACAA GTGGAAAACG TACCGGGGAG GGGGCGTGAA GGCCTGCTCG
CTCACGTGCC TAGCGGAAGG CTTCAACTTC TACACGGAGA GGGCGGCAGC CGTGGTGGAC
GGGACACCCT GCCGTCCAGA CACGGTGGAC ATTTGCGTCA GTGGCGAATG CAAGCACGTG
GGCTGCGACC GAGTCCTGGG CTCCGACCTG CGGGAGGACA AGTGCCGAGT GTGTGGCGGT
GACGGCAGTG CCTGCGAGAC CATCGAGGGC GTCTTCAGCC CAGCCTCACC TGGGGCCGGG
TACGAGGATG TCGTCTGGAT TCCCAAAGGC TCCGTCCACA TCTTCATCCA GGATCTGAAC
CTCTCTCTCA GTCACTTGGC CCTGAAGGGA GACCAGGAGT CCCTGCTGCT GGAGGGGCTG
CCTGGGACCC CCCAGCCCCA CCGTCTGCCT CTAGCTGGGA CCACCTTTCA ACTGCGACAG
GGGCCAGACC AGGTCCAGAG CCTCGAAGCC CTGGGACCGA TTAATGCATC TCTCATCGTC
ATGGTGCTGG CCCGGACCGA GCTGCCTGCC CTCCGCTACC GCTTCAATGC CCCCATCGCC
CGTGACTCGC TGCCCCCCTA CTCCTGGCAC TATGCGCCCT GGACCAAGTG CTCGGCCCAG
TGTGCAGGCG GTAGCCAGGT GCAGGCGGTG GAGTGCCGCA ACCAGCTGGA CAGCTCCGCG
GTCGCCCCCC ACTACTGCAG TGCCCACAGC AAGCTGCCCA AAAGGCAGCG CGCCTGCAAC
ACGGAGCCTT GCCCTCCAGA CTGGGTTGTA GGGAACTGGT CGCTCTGCAG CCGCAGCTGC
GATGCAGGCG TGCGCAGCCG CTCGGTCGTG TGCCAGCGCC GCGTCTCTGC CGCGGAGGAG
AAGGCGCTGG ACGACAGCGC ATGCCCGCAG CCGCGCCCAC CTGTACTGGA GGCCTGCCAC
GGCCCCACTT GCCCTCCGGA GTGGGCGGCC CTCGACTGGT CTGAGGTCAG CCGCCCCCTT
CCTTCGCGCC CACTGGGATG CCCAGGTGGG GTGTCCACGG AGACGCCTCT GCGCGGTCTC
CAGGTTAGCT GTCCCCTCCT CACTTCGCAC TGGGGCAGCA CCCTGAGCAC GAAACGCCCC
TTCCAACTGC AGTGCACCCC CAGCTGCGGG CCGGGCCTCC GCCACCGCGT GGTCCTTTGC
AAGAGCGCAG ACCACCGCGC CACGCTGCCC CCGGCGCACT GCTCACCCGC CGCCAAGCCA
CCGGCCACCA TGCGCTGCAA CTTGCGCCGC TGCCCCCCGG CCCGCTGGGT GGCTGGCGAG
TGGGGTGAGT GCTCTGCACA GTGCGGCGTC GGGCAGCGGC AGCGCTCGGT GCGCTGCACC
AGCCACACGG GCCAGGCGTC GCACGAGTGC ACGGAGGCCC TGCGGCCGCC CACCACGCAG
CAGTGTGAGG CCAAGTGCGA CAGCCCAACC CCCGGGGACG GCCCTGAAGA GTGCAAGGAT
GTGAACAAGG TCGCCTACTG CCCCCTGGTG CTCAAATTTC AGTTCTGCAG CCGAGCCTAC
TTCCGCCAGA TGTGCTGCAA AACCTGCCAT GGCCACTAG
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqXP_011526635.1
CDS208..3666
Misc Feature(1)322..747(+)
Misc Feature(2)922..1578(+)
Misc Feature(3)922..1569(+)
Misc Feature(4)1381..1413(+)
Misc Feature(5)1855..2013(+)
Misc Feature(6)2323..2661(+)
Misc Feature(7)2692..2862(+)
Misc Feature(8)3382..3516(+)
Misc Feature(9)3556..3654(+)
Translation
Position Chain Variation Link
280 280 a, g dbSNP:121434358
286 286 a, c, t dbSNP:111234410
563 563 a, c, g dbSNP:3814291
608 608 c, g dbSNP:7255721
916 916 c, t dbSNP:121434357
975 975 g, t dbSNP:200589780
985 985 a, g dbSNP:756947226
1159 1159 c, t dbSNP:121434359
1205 1205 a, c dbSNP:775640275
1267 1267 a, g dbSNP:759348240
1760 1760 a, g dbSNP:267606636
2143 2143 a, g dbSNP:148605664
2172 2172 a, g dbSNP:113579886
2176 2176 a, g dbSNP:202232012
2305 2305 a, g, t dbSNP:267606637
3547 3547 a, g dbSNP:80046653
3657 3657 g, t dbSNP:7252299
3988 3988 -, c dbSNP:150352175
4000 4000 g, t dbSNP:745911505
4113 4113 -, g dbSNP:527806324

Target ORF information:

RefSeq Version XM_011528333
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif, 10 (ADAMTS10), transcript variant X3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011528333

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
3061
3121
3181
3241
3301
3361
3421
ATGGCTCCCG CCTGCCAGAT CCTCCGCTGG GCCCTCGCCC TGGGGCTGGG CCTCATGTTC 
GAGGTCACGC ACGCCTTCCG GTCTCAAGAT GAGTTCCTGT CCAGTCTGGA GAGCTATGAG
ATCGCCTTCC CCACCCGCGT GGACCACAAC GGGGCACTGC TGGCCTTCTC GCCACCTCCT
CCCCGGAGGC AGCGCCGCGG CACGGGGGCC ACAGCCGAGT CCCGCCTCTT CTACAAAGTG
GCCTCGCCCA GCACCCACTT CCTGCTGAAC CTGACCCGCA GCTCCCGTCT ACTGGCAGGG
CACGTCTCCG TGGAGTACTG GACACGGGAG GGCCTGGCCT GGCAGAGGGC GGCCCGGCCC
CACTGCCTCT ACGCTGGTCA CCTGCAGGGC CAGGCCAGCA GCTCCCATGT GGCCATCAGC
ACCTGTGGAG GCCTGCACGG CCTGATCGTG GCAGACGAGG AAGAGTACCT GATTGAGCCC
CTGCACGGTG GGCCCAAGGG TTCTCGGAGC CCGGAGGAAA GTGGACCACA TGTGGTGTAC
AAGCGTTCCT CTCTGCGTCA CCCCCACCTG GACACAGCCT GTGGAGTGAG AGATGAGAAA
CCGTGGAAAG GGCGGCCATG GTGGCTGCGG ACCTTGAAGC CACCGCCTGC CAGGCCCCTG
GGGAATGAAA CAGAGCGTGG CCAGCCAGGC CTGAAGCGAT CGGTCAGCCG AGAGCGCTAC
GTGGAGACCC TGGTGGTGGC TGACAAGATG ATGGTGGCCT ATCACGGGCG CCGGGATGTG
GAGCAGTATG TCCTGGCCAT CATGAACATT GTTGCCAAAC TTTTCCAGGA CTCGAGTCTG
GGAAGCACCG TTAACATCCT CGTAACTCGC CTCATCCTGC TCACGGAGGA CCAGCCCACT
CTGGAGATCA CCCACCATGC CGGGAAGTCC CTGGACAGCT TCTGTAAGTG GCAGAAATCC
ATCGTGAACC ACAGCGGCCA TGGCAATGCC ATTCCAGAGA ACGGTGTGGC TAACCATGAC
ACAGCAGTGC TCATCACACG CTATGACATC TGCATCTACA AGAACAAACC CTGCGGCACA
CTAGGCCTGG CCCCGGTGGG CGGAATGTGT GAGCGCGAGA GAAGCTGCAG CGTCAATGAG
GACATTGGCC TGGCCACAGC GTTCACCATT GCCCACGAGA TCGGGCACAC ATTCGGCATG
AACCATGACG GCGTGGGAAA CAGCTGTGGG GCCCGTGGTC AGGACCCAGC CAAGCTCATG
GCTGCCCACA TTACCATGAA GACCAACCCA TTCGTGTGGT CATCCTGCAG CCGTGACTAC
ATCACCAGCT TTCTAGACTC GGGCCTGGGG CTCTGCCTGA ACAACCGGCC CCCCAGACAG
GACTTTGTGT ACCCGACAGT GGCACCGGGC CAAGCCTACG ATGCAGATGA GCAATGCCGC
TTTCAGCATG GAGTCAAATC GCGTCAGTGT AAATACGGGG AGGTCTGCAG CGAGCTGTGG
TGTCTGAGCA AGAGCAACCG GTGCATCACC AACAGCATCC CGGCCGCCGA GGGCACGCTG
TGCCAGACGC ACACCATCGA CAAGGGGTGG TGCTACAAAC GGGTCTGTGT CCCCTTTGGG
TCGCGCCCAG AGGGTGTGGA CGGAGCCTGG GGGCCGTGGA CTCCATGGGG CGACTGCAGC
CGGACCTGTG GCGGCGGCGT GTCCTCTTCT AGCCGTCACT GCGACAGCCC CAGGCCAACC
ATCGGGGGCA AGTACTGTCT GGGTGAGAGA AGGCGGCACC GCTCCTGCAA CACGGATGAC
TGTCCCCCTG GCTCCCAGGA CTTCAGAGAA GTGCAGTGTT CTGAATTTGA CAGCATCCCT
TTCCGTGGGA AATTCTACAA GTGGAAAACG TACCGGGGAG GGGGCGTGAA GGCCTGCTCG
CTCACGTGCC TAGCGGAAGG CTTCAACTTC TACACGGAGA GGGCGGCAGC CGTGGTGGAC
GGGACACCCT GCCGTCCAGA CACGGTGGAC ATTTGCGTCA GTGGCGAATG CAAGCACGTG
GGCTGCGACC GAGTCCTGGG CTCCGACCTG CGGGAGGACA AGTGCCGAGT GTGTGGCGGT
GACGGCAGTG CCTGCGAGAC CATCGAGGGC GTCTTCAGCC CAGCCTCACC TGGGGCCGGG
TACGAGGATG TCGTCTGGAT TCCCAAAGGC TCCGTCCACA TCTTCATCCA GGATCTGAAC
CTCTCTCTCA GTCACTTGGC CCTGAAGGGA GACCAGGAGT CCCTGCTGCT GGAGGGGCTG
CCTGGGACCC CCCAGCCCCA CCGTCTGCCT CTAGCTGGGA CCACCTTTCA ACTGCGACAG
GGGCCAGACC AGGTCCAGAG CCTCGAAGCC CTGGGACCGA TTAATGCATC TCTCATCGTC
ATGGTGCTGG CCCGGACCGA GCTGCCTGCC CTCCGCTACC GCTTCAATGC CCCCATCGCC
CGTGACTCGC TGCCCCCCTA CTCCTGGCAC TATGCGCCCT GGACCAAGTG CTCGGCCCAG
TGTGCAGGCG GTAGCCAGGT GCAGGCGGTG GAGTGCCGCA ACCAGCTGGA CAGCTCCGCG
GTCGCCCCCC ACTACTGCAG TGCCCACAGC AAGCTGCCCA AAAGGCAGCG CGCCTGCAAC
ACGGAGCCTT GCCCTCCAGA CTGGGTTGTA GGGAACTGGT CGCTCTGCAG CCGCAGCTGC
GATGCAGGCG TGCGCAGCCG CTCGGTCGTG TGCCAGCGCC GCGTCTCTGC CGCGGAGGAG
AAGGCGCTGG ACGACAGCGC ATGCCCGCAG CCGCGCCCAC CTGTACTGGA GGCCTGCCAC
GGCCCCACTT GCCCTCCGGA GTGGGCGGCC CTCGACTGGT CTGAGGTCAG CCGCCCCCTT
CCTTCGCGCC CACTGGGATG CCCAGGTGGG GTGTCCACGG AGACGCCTCT GCGCGGTCTC
CAGGTTAGCT GTCCCCTCCT CACTTCGCAC TGGGGCAGCA CCCTGAGCAC GAAACGCCCC
TTCCAACTGC AGTGCACCCC CAGCTGCGGG CCGGGCCTCC GCCACCGCGT GGTCCTTTGC
AAGAGCGCAG ACCACCGCGC CACGCTGCCC CCGGCGCACT GCTCACCCGC CGCCAAGCCA
CCGGCCACCA TGCGCTGCAA CTTGCGCCGC TGCCCCCCGG CCCGCTGGGT GGCTGGCGAG
TGGGGTGAGT GCTCTGCACA GTGCGGCGTC GGGCAGCGGC AGCGCTCGGT GCGCTGCACC
AGCCACACGG GCCAGGCGTC GCACGAGTGC ACGGAGGCCC TGCGGCCGCC CACCACGCAG
CAGTGTGAGG CCAAGTGCGA CAGCCCAACC CCCGGGGACG GCCCTGAAGA GTGCAAGGAT
GTGAACAAGG TCGCCTACTG CCCCCTGGTG CTCAAATTTC AGTTCTGCAG CCGAGCCTAC
TTCCGCCAGA TGTGCTGCAA AACCTGCCAT GGCCACTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu72992
Accession Version XM_011528334.1
Sequence Information ORF Nucleotide Sequence (Length: 3135bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product A disintegrin and metalloproteinase with thrombospondin motifs 10 isoform X2
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_011295.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
3061
3121
ATGGCTCCCG CCTGCCAGAT CCTCCGCTGG GCCCTCGCCC TGGGGCTGGG CCTCATGTTC 
GAGGTCACGC ACGCCTTCCG GTCTCAAGAT GAGTTCCTGT CCAGTCTGGA GAGCTATGAG
ATCGCCTTCC CCACCCGCGT GGACCACAAC GGGGCACTGC TGGCCTTCTC GCCACCTCCT
CCCCGGAGGC AGCGCCGCGG CACGGGGGCC ACAGCCGAGT CCCGCCTCTT CTACAAAGTG
GCCTCGCCCA GCACCCACTT CCTGCTGAAC CTGACCCGCA GCTCCCGTCT ACTGGCAGGG
CACGTCTCCG TGGAGTACTG GACACGGGAG GGCCTGGCCT GGCAGAGGGC GGCCCGGCCC
CACTGCCTCT ACGCTGGTCA CCTGCAGGGC CAGGCCAGCA GCTCCCATGT GGCCATCAGC
ACCTGTGGAG GCCTGCACGG CCTGATCGTG GCAGACGAGG AAGAGTACCT GATTGAGCCC
CTGCACGGTG GGCCCAAGGG TTCTCGGAGC CCGGAGGAAA GTGGACCACA TGTGGTGTAC
AAGCGTTCCT CTCTGCGTCA CCCCCACCTG GACACAGCCT GTGGAGTGAG AGATGAGAAA
CCGTGGAAAG GGCGGCCATG GTGGCTGCGG ACCTTGAAGC CACCGCCTGC CAGGCCCCTG
GGGAATGAAA CAGAGCGTGG CCAGCCAGGC CTGAAGCGAT CGGTCAGCCG AGAGCGCTAC
GTGGAGACCC TGGTGGTGGC TGACAAGATG ATGGTGGCCT ATCACGGGCG CCGGGATGTG
GAGCAGTATG TCCTGGCCAT CATGAACATT GTTGCCAAAC TTTTCCAGGA CTCGAGTCTG
GGAAGCACCG TTAACATCCT CGTAACTCGC CTCATCCTGC TCACGGAGGA CCAGCCCACT
CTGGAGATCA CCCACCATGC CGGGAAGTCC CTGGACAGCT TCTGTAAGTG GCAGAAATCC
ATCGTGAACC ACAGCGGCCA TGGCAATGCC ATTCCAGAGA ACGGTGTGGC TAACCATGAC
ACAGCAGTGC TCATCACACG CTATGACATC TGCATCTACA AGAACAAACC CTGCGGCACA
CTAGGCCTGG CCCCGGTGGG CGGAATGTGT GAGCGCGAGA GAAGCTGCAG CGTCAATGAG
GACATTGGCC TGGCCACAGC GTTCACCATT GCCCACGAGA TCGGGCACAC ATTCGGCATG
AACCATGACG GCGTGGGAAA CAGCTGTGGG GCCCGTGGTC AGGACCCAGC CAAGCTCATG
GCTGCCCACA TTACCATGAA GACCAACCCA TTCGTGTGGT CATCCTGCAG CCGTGACTAC
ATCACCAGCT TTCTAGACTC GGGCCTGGGG CTCTGCCTGA ACAACCGGCC CCCCAGACAG
GACTTTGTGT ACCCGACAGT GGCACCGGGC CAAGCCTACG ATGCAGATGA GCAATGCCGC
TTTCAGCATG GAGTCAAATC GCGTCAGTGT AAATACGGGG AGGTCTGCAG CGAGCTGTGG
TGTCTGAGCA AGAGCAACCG GTGCATCACC AACAGCATCC CGGCCGCCGA GGGCACGCTG
TGCCAGACGC ACACCATCGA CAAGGGGTGG TGCTACAAAC GGGTCTGTGT CCCCTTTGGG
TCGCGCCCAG AGGGTGTGGA CGGAGCCTGG GGGCCGTGGA CTCCATGGGG CGACTGCAGC
CGGACCTGTG GCGGCGGCGT GTCCTCTTCT AGCCGTCACT GCGACAGCCC CAGGCCAACC
ATCGGGGGCA AGTACTGTCT GGGTGAGAGA AGGCGGCACC GCTCCTGCAA CACGGATGAC
TGTCCCCCTG GCTCCCAGGA CTTCAGAGAA GTGCAGTGTT CTGAATTTGA CAGCATCCCT
TTCCGTGGGA AATTCTACAA GTGGAAAACG TACCGGGGAG GGGGCGTGAA GGCCTGCTCG
CTCACGTGCC TAGCGGAAGG CTTCAACTTC TACACGGAGA GGGCGGCAGC CGTGGTGGAC
GGGACACCCT GCCGTCCAGA CACGGTGGAC ATTTGCGTCA GTGGCGAATG CAAGCACGTG
GGCTGCGACC GAGTCCTGGG CTCCGACCTG CGGGAGGACA AGTGCCGAGT GTGTGGCGGT
GACGGCAGTG CCTGCGAGAC CATCGAGGGC GTCTTCAGCC CAGCCTCACC TGGGGCCGGG
TACGAGGATG TCGTCTGGAT TCCCAAAGGC TCCGTCCACA TCTTCATCCA GGATCTGAAC
CTCTCTCTCA GTCACTTGGC CCTGAAGGGA GACCAGGAGT CCCTGCTGCT GGAGGGGCTG
CCTGGGACCC CCCAGCCCCA CCGTCTGCCT CTAGCTGGGA CCACCTTTCA ACTGCGACAG
GGGCCAGACC AGGTCCAGAG CCTCGAAGCC CTGGGACCGA TTAATGCATC TCTCATCGTC
ATGGTGCTGG CCCGGACCGA GCTGCCTGCC CTCCGCTACC GCTTCAATGC CCCCATCGCC
CGTGACTCGC TGCCCCCCTA CTCCTGGCAC TATGCGCCCT GGACCAAGTG CTCGGCCCAG
TGTGCAGGCG GTAGCCAGGT GCAGGCGGTG GAGTGCCGCA ACCAGCTGGA CAGCTCCGCG
GTCGCCCCCC ACTACTGCAG TGCCCACAGC AAGCTGCCCA AAAGGCAGCG CGCCTGCAAC
ACGGAGCCTT GCCCTCCAGA CTGGGTTGTA GGGAACTGGT CGCTCTGCAG CCGCAGCTGC
GATGCAGGCG TGCGCAGCCG CTCGGTCGTG TGCCAGCGCC GCGTCTCTGC CGCGGAGGAG
AAGGCGCTGG ACGACAGCGC ATGCCCGCAG CCGCGCCCAC CTGTACTGGA GGCCTGCCAC
GGCCCCACTT GCCCTCCGGA GTGGGCGGCC CTCGACTGGT CTGAGTGCTC TGCACAGTGC
GGCGTCGGGC AGCGGCAGCG CTCGGTGCGC TGCACCAGCC ACACGGGCCA GGCGTCGCAC
GAGTGCACGG AGGCCCTGCG GCCGCCCACC ACGCAGCAGT GTGAGGCCAA GTGCGACAGC
CCAACCCCCG GGGACGGCCC TGAAGAGTGC AAGGATGTGA ACAAGGTCGC CTACTGCCCC
CTGGTGCTCA AATTTCAGTT CTGCAGCCGA GCCTACTTCC GCCAGATGTG CTGCAAAACC
TGCCATGGCC ACTAG
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqXP_011526636.1
CDS278..3412
Misc Feature(1)392..817(+)
Misc Feature(2)992..1648(+)
Misc Feature(3)992..1639(+)
Misc Feature(4)1451..1483(+)
Misc Feature(5)1925..2083(+)
Misc Feature(6)2393..2731(+)
Misc Feature(7)2762..2932(+)
Misc Feature(8)3131..3262(+)
Misc Feature(9)3302..3400(+)
Translation
Position Chain Variation Link
350 350 a, g dbSNP:121434358
356 356 a, c, t dbSNP:111234410
633 633 a, c, g dbSNP:3814291
678 678 c, g dbSNP:7255721
986 986 c, t dbSNP:121434357
1045 1045 g, t dbSNP:200589780
1055 1055 a, g dbSNP:756947226
1229 1229 c, t dbSNP:121434359
1275 1275 a, c dbSNP:775640275
1337 1337 a, g dbSNP:759348240
1830 1830 a, g dbSNP:267606636
2213 2213 a, g dbSNP:148605664
2242 2242 a, g dbSNP:113579886
2246 2246 a, g dbSNP:202232012
2375 2375 a, g, t dbSNP:267606637
3293 3293 a, g dbSNP:80046653
3403 3403 g, t dbSNP:7252299
3734 3734 -, c dbSNP:150352175
3746 3746 g, t dbSNP:745911505
3859 3859 -, g dbSNP:527806324

Target ORF information:

RefSeq Version XM_011528334
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif, 10 (ADAMTS10), transcript variant X4, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011528334

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
3061
3121
ATGGCTCCCG CCTGCCAGAT CCTCCGCTGG GCCCTCGCCC TGGGGCTGGG CCTCATGTTC 
GAGGTCACGC ACGCCTTCCG GTCTCAAGAT GAGTTCCTGT CCAGTCTGGA GAGCTATGAG
ATCGCCTTCC CCACCCGCGT GGACCACAAC GGGGCACTGC TGGCCTTCTC GCCACCTCCT
CCCCGGAGGC AGCGCCGCGG CACGGGGGCC ACAGCCGAGT CCCGCCTCTT CTACAAAGTG
GCCTCGCCCA GCACCCACTT CCTGCTGAAC CTGACCCGCA GCTCCCGTCT ACTGGCAGGG
CACGTCTCCG TGGAGTACTG GACACGGGAG GGCCTGGCCT GGCAGAGGGC GGCCCGGCCC
CACTGCCTCT ACGCTGGTCA CCTGCAGGGC CAGGCCAGCA GCTCCCATGT GGCCATCAGC
ACCTGTGGAG GCCTGCACGG CCTGATCGTG GCAGACGAGG AAGAGTACCT GATTGAGCCC
CTGCACGGTG GGCCCAAGGG TTCTCGGAGC CCGGAGGAAA GTGGACCACA TGTGGTGTAC
AAGCGTTCCT CTCTGCGTCA CCCCCACCTG GACACAGCCT GTGGAGTGAG AGATGAGAAA
CCGTGGAAAG GGCGGCCATG GTGGCTGCGG ACCTTGAAGC CACCGCCTGC CAGGCCCCTG
GGGAATGAAA CAGAGCGTGG CCAGCCAGGC CTGAAGCGAT CGGTCAGCCG AGAGCGCTAC
GTGGAGACCC TGGTGGTGGC TGACAAGATG ATGGTGGCCT ATCACGGGCG CCGGGATGTG
GAGCAGTATG TCCTGGCCAT CATGAACATT GTTGCCAAAC TTTTCCAGGA CTCGAGTCTG
GGAAGCACCG TTAACATCCT CGTAACTCGC CTCATCCTGC TCACGGAGGA CCAGCCCACT
CTGGAGATCA CCCACCATGC CGGGAAGTCC CTGGACAGCT TCTGTAAGTG GCAGAAATCC
ATCGTGAACC ACAGCGGCCA TGGCAATGCC ATTCCAGAGA ACGGTGTGGC TAACCATGAC
ACAGCAGTGC TCATCACACG CTATGACATC TGCATCTACA AGAACAAACC CTGCGGCACA
CTAGGCCTGG CCCCGGTGGG CGGAATGTGT GAGCGCGAGA GAAGCTGCAG CGTCAATGAG
GACATTGGCC TGGCCACAGC GTTCACCATT GCCCACGAGA TCGGGCACAC ATTCGGCATG
AACCATGACG GCGTGGGAAA CAGCTGTGGG GCCCGTGGTC AGGACCCAGC CAAGCTCATG
GCTGCCCACA TTACCATGAA GACCAACCCA TTCGTGTGGT CATCCTGCAG CCGTGACTAC
ATCACCAGCT TTCTAGACTC GGGCCTGGGG CTCTGCCTGA ACAACCGGCC CCCCAGACAG
GACTTTGTGT ACCCGACAGT GGCACCGGGC CAAGCCTACG ATGCAGATGA GCAATGCCGC
TTTCAGCATG GAGTCAAATC GCGTCAGTGT AAATACGGGG AGGTCTGCAG CGAGCTGTGG
TGTCTGAGCA AGAGCAACCG GTGCATCACC AACAGCATCC CGGCCGCCGA GGGCACGCTG
TGCCAGACGC ACACCATCGA CAAGGGGTGG TGCTACAAAC GGGTCTGTGT CCCCTTTGGG
TCGCGCCCAG AGGGTGTGGA CGGAGCCTGG GGGCCGTGGA CTCCATGGGG CGACTGCAGC
CGGACCTGTG GCGGCGGCGT GTCCTCTTCT AGCCGTCACT GCGACAGCCC CAGGCCAACC
ATCGGGGGCA AGTACTGTCT GGGTGAGAGA AGGCGGCACC GCTCCTGCAA CACGGATGAC
TGTCCCCCTG GCTCCCAGGA CTTCAGAGAA GTGCAGTGTT CTGAATTTGA CAGCATCCCT
TTCCGTGGGA AATTCTACAA GTGGAAAACG TACCGGGGAG GGGGCGTGAA GGCCTGCTCG
CTCACGTGCC TAGCGGAAGG CTTCAACTTC TACACGGAGA GGGCGGCAGC CGTGGTGGAC
GGGACACCCT GCCGTCCAGA CACGGTGGAC ATTTGCGTCA GTGGCGAATG CAAGCACGTG
GGCTGCGACC GAGTCCTGGG CTCCGACCTG CGGGAGGACA AGTGCCGAGT GTGTGGCGGT
GACGGCAGTG CCTGCGAGAC CATCGAGGGC GTCTTCAGCC CAGCCTCACC TGGGGCCGGG
TACGAGGATG TCGTCTGGAT TCCCAAAGGC TCCGTCCACA TCTTCATCCA GGATCTGAAC
CTCTCTCTCA GTCACTTGGC CCTGAAGGGA GACCAGGAGT CCCTGCTGCT GGAGGGGCTG
CCTGGGACCC CCCAGCCCCA CCGTCTGCCT CTAGCTGGGA CCACCTTTCA ACTGCGACAG
GGGCCAGACC AGGTCCAGAG CCTCGAAGCC CTGGGACCGA TTAATGCATC TCTCATCGTC
ATGGTGCTGG CCCGGACCGA GCTGCCTGCC CTCCGCTACC GCTTCAATGC CCCCATCGCC
CGTGACTCGC TGCCCCCCTA CTCCTGGCAC TATGCGCCCT GGACCAAGTG CTCGGCCCAG
TGTGCAGGCG GTAGCCAGGT GCAGGCGGTG GAGTGCCGCA ACCAGCTGGA CAGCTCCGCG
GTCGCCCCCC ACTACTGCAG TGCCCACAGC AAGCTGCCCA AAAGGCAGCG CGCCTGCAAC
ACGGAGCCTT GCCCTCCAGA CTGGGTTGTA GGGAACTGGT CGCTCTGCAG CCGCAGCTGC
GATGCAGGCG TGCGCAGCCG CTCGGTCGTG TGCCAGCGCC GCGTCTCTGC CGCGGAGGAG
AAGGCGCTGG ACGACAGCGC ATGCCCGCAG CCGCGCCCAC CTGTACTGGA GGCCTGCCAC
GGCCCCACTT GCCCTCCGGA GTGGGCGGCC CTCGACTGGT CTGAGTGCTC TGCACAGTGC
GGCGTCGGGC AGCGGCAGCG CTCGGTGCGC TGCACCAGCC ACACGGGCCA GGCGTCGCAC
GAGTGCACGG AGGCCCTGCG GCCGCCCACC ACGCAGCAGT GTGAGGCCAA GTGCGACAGC
CCAACCCCCG GGGACGGCCC TGAAGAGTGC AAGGATGTGA ACAAGGTCGC CTACTGCCCC
CTGGTGCTCA AATTTCAGTT CTGCAGCCGA GCCTACTTCC GCCAGATGTG CTGCAAAACC
TGCCATGGCC ACTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu51850
Accession Version XM_006722917.2
Sequence Information ORF Nucleotide Sequence (Length: 2355bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product A disintegrin and metalloproteinase with thrombospondin motifs 10 isoform X3
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_011295.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 12, 2015 this sequence version replaced gi:578833668. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
ATGTGTGAGC GCGAGAGAAG CTGCAGCGTC AATGAGGACA TTGGCCTGGC CACAGCGTTC 
ACCATTGCCC ACGAGATCGG GCACACATTC GGCATGAACC ATGACGGCGT GGGAAACAGC
TGTGGGGCCC GTGGTCAGGA CCCAGCCAAG CTCATGGCTG CCCACATTAC CATGAAGACC
AACCCATTCG TGTGGTCATC CTGCAGCCGT GACTACATCA CCAGCTTTCT AGACTCGGGC
CTGGGGCTCT GCCTGAACAA CCGGCCCCCC AGACAGGACT TTGTGTACCC GACAGTGGCA
CCGGGCCAAG CCTACGATGC AGATGAGCAA TGCCGCTTTC AGCATGGAGT CAAATCGCGT
CAGTGTAAAT ACGGGGAGGT CTGCAGCGAG CTGTGGTGTC TGAGCAAGAG CAACCGGTGC
ATCACCAACA GCATCCCGGC CGCCGAGGGC ACGCTGTGCC AGACGCACAC CATCGACAAG
GGGTGGTGCT ACAAACGGGT CTGTGTCCCC TTTGGGTCGC GCCCAGAGGG TGTGGACGGA
GCCTGGGGGC CGTGGACTCC ATGGGGCGAC TGCAGCCGGA CCTGTGGCGG CGGCGTGTCC
TCTTCTAGCC GTCACTGCGA CAGCCCCAGG CCAACCATCG GGGGCAAGTA CTGTCTGGGT
GAGAGAAGGC GGCACCGCTC CTGCAACACG GATGACTGTC CCCCTGGCTC CCAGGACTTC
AGAGAAGTGC AGTGTTCTGA ATTTGACAGC ATCCCTTTCC GTGGGAAATT CTACAAGTGG
AAAACGTACC GGGGAGGGGG CGTGAAGGCC TGCTCGCTCA CGTGCCTAGC GGAAGGCTTC
AACTTCTACA CGGAGAGGGC GGCAGCCGTG GTGGACGGGA CACCCTGCCG TCCAGACACG
GTGGACATTT GCGTCAGTGG CGAATGCAAG CACGTGGGCT GCGACCGAGT CCTGGGCTCC
GACCTGCGGG AGGACAAGTG CCGAGTGTGT GGCGGTGACG GCAGTGCCTG CGAGACCATC
GAGGGCGTCT TCAGCCCAGC CTCACCTGGG GCCGGGTACG AGGATGTCGT CTGGATTCCC
AAAGGCTCCG TCCACATCTT CATCCAGGAT CTGAACCTCT CTCTCAGTCA CTTGGCCCTG
AAGGGAGACC AGGAGTCCCT GCTGCTGGAG GGGCTGCCTG GGACCCCCCA GCCCCACCGT
CTGCCTCTAG CTGGGACCAC CTTTCAACTG CGACAGGGGC CAGACCAGGT CCAGAGCCTC
GAAGCCCTGG GACCGATTAA TGCATCTCTC ATCGTCATGG TGCTGGCCCG GACCGAGCTG
CCTGCCCTCC GCTACCGCTT CAATGCCCCC ATCGCCCGTG ACTCGCTGCC CCCCTACTCC
TGGCACTATG CGCCCTGGAC CAAGTGCTCG GCCCAGTGTG CAGGCGGTAG CCAGGTGCAG
GCGGTGGAGT GCCGCAACCA GCTGGACAGC TCCGCGGTCG CCCCCCACTA CTGCAGTGCC
CACAGCAAGC TGCCCAAAAG GCAGCGCGCC TGCAACACGG AGCCTTGCCC TCCAGACTGG
GTTGTAGGGA ACTGGTCGCT CTGCAGCCGC AGCTGCGATG CAGGCGTGCG CAGCCGCTCG
GTCGTGTGCC AGCGCCGCGT CTCTGCCGCG GAGGAGAAGG CGCTGGACGA CAGCGCATGC
CCGCAGCCGC GCCCACCTGT ACTGGAGGCC TGCCACGGCC CCACTTGCCC TCCGGAGTGG
GCGGCCCTCG ACTGGTCTGA GGTCAGCCGC CCCCTTCCTT CGCGCCCACT GGGATGCCCA
GGTGGGGTGT CCACGGAGAC GCCTCTGCGC GGTCTCCAGG TTAGCTGTCC CCTCCTCACT
TCGCACTGGG GCAGCACCCT GAGCACGAAA CGCCCCTTCC AACTGCAGTG CACCCCCAGC
TGCGGGCCGG GCCTCCGCCA CCGCGTGGTC CTTTGCAAGA GCGCAGACCA CCGCGCCACG
CTGCCCCCGG CGCACTGCTC ACCCGCCGCC AAGCCACCGG CCACCATGCG CTGCAACTTG
CGCCGCTGCC CCCCGGCCCG CTGGGTGGCT GGCGAGTGGG GTGAGTGCTC TGCACAGTGC
GGCGTCGGGC AGCGGCAGCG CTCGGTGCGC TGCACCAGCC ACACGGGCCA GGCGTCGCAC
GAGTGCACGG AGGCCCTGCG GCCGCCCACC ACGCAGCAGT GTGAGGCCAA GTGCGACAGC
CCAACCCCCG GGGACGGCCC TGAAGAGTGC AAGGATGTGA ACAAGGTCGC CTACTGCCCC
CTGGTGCTCA AATTTCAGTT CTGCAGCCGA GCCTACTTCC GCCAGATGTG CTGCAAAACC
TGCCATGGCC ACTAG
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqXP_006722980.1
CDS1319..3673
Misc Feature(1)1319..1576(+)
Misc Feature(2)1388..1420(+)
Misc Feature(3)1862..2020(+)
Misc Feature(4)2330..2668(+)
Misc Feature(5)3389..3523(+)
Misc Feature(6)3563..3661(+)
Translation
Position Chain Variation Link
282 282 a, g dbSNP:121434358
288 288 a, c, t dbSNP:111234410
565 565 a, c, g dbSNP:3814291
610 610 c, g dbSNP:7255721
918 918 c, t dbSNP:121434357
977 977 g, t dbSNP:200589780
987 987 a, g dbSNP:756947226
1166 1166 c, t dbSNP:121434359
1212 1212 a, c dbSNP:775640275
1274 1274 a, g dbSNP:759348240
1767 1767 a, g dbSNP:267606636
2150 2150 a, g dbSNP:148605664
2179 2179 a, g dbSNP:113579886
2183 2183 a, g dbSNP:202232012
2312 2312 a, g, t dbSNP:267606637
3554 3554 a, g dbSNP:80046653
3664 3664 g, t dbSNP:7252299
3995 3995 -, c dbSNP:150352175
4007 4007 g, t dbSNP:745911505
4120 4120 -, g dbSNP:527806324

Target ORF information:

RefSeq Version XM_006722917
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif, 10 (ADAMTS10), transcript variant X5, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_006722917

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
ATGTGTGAGC GCGAGAGAAG CTGCAGCGTC AATGAGGACA TTGGCCTGGC CACAGCGTTC 
ACCATTGCCC ACGAGATCGG GCACACATTC GGCATGAACC ATGACGGCGT GGGAAACAGC
TGTGGGGCCC GTGGTCAGGA CCCAGCCAAG CTCATGGCTG CCCACATTAC CATGAAGACC
AACCCATTCG TGTGGTCATC CTGCAGCCGT GACTACATCA CCAGCTTTCT AGACTCGGGC
CTGGGGCTCT GCCTGAACAA CCGGCCCCCC AGACAGGACT TTGTGTACCC GACAGTGGCA
CCGGGCCAAG CCTACGATGC AGATGAGCAA TGCCGCTTTC AGCATGGAGT CAAATCGCGT
CAGTGTAAAT ACGGGGAGGT CTGCAGCGAG CTGTGGTGTC TGAGCAAGAG CAACCGGTGC
ATCACCAACA GCATCCCGGC CGCCGAGGGC ACGCTGTGCC AGACGCACAC CATCGACAAG
GGGTGGTGCT ACAAACGGGT CTGTGTCCCC TTTGGGTCGC GCCCAGAGGG TGTGGACGGA
GCCTGGGGGC CGTGGACTCC ATGGGGCGAC TGCAGCCGGA CCTGTGGCGG CGGCGTGTCC
TCTTCTAGCC GTCACTGCGA CAGCCCCAGG CCAACCATCG GGGGCAAGTA CTGTCTGGGT
GAGAGAAGGC GGCACCGCTC CTGCAACACG GATGACTGTC CCCCTGGCTC CCAGGACTTC
AGAGAAGTGC AGTGTTCTGA ATTTGACAGC ATCCCTTTCC GTGGGAAATT CTACAAGTGG
AAAACGTACC GGGGAGGGGG CGTGAAGGCC TGCTCGCTCA CGTGCCTAGC GGAAGGCTTC
AACTTCTACA CGGAGAGGGC GGCAGCCGTG GTGGACGGGA CACCCTGCCG TCCAGACACG
GTGGACATTT GCGTCAGTGG CGAATGCAAG CACGTGGGCT GCGACCGAGT CCTGGGCTCC
GACCTGCGGG AGGACAAGTG CCGAGTGTGT GGCGGTGACG GCAGTGCCTG CGAGACCATC
GAGGGCGTCT TCAGCCCAGC CTCACCTGGG GCCGGGTACG AGGATGTCGT CTGGATTCCC
AAAGGCTCCG TCCACATCTT CATCCAGGAT CTGAACCTCT CTCTCAGTCA CTTGGCCCTG
AAGGGAGACC AGGAGTCCCT GCTGCTGGAG GGGCTGCCTG GGACCCCCCA GCCCCACCGT
CTGCCTCTAG CTGGGACCAC CTTTCAACTG CGACAGGGGC CAGACCAGGT CCAGAGCCTC
GAAGCCCTGG GACCGATTAA TGCATCTCTC ATCGTCATGG TGCTGGCCCG GACCGAGCTG
CCTGCCCTCC GCTACCGCTT CAATGCCCCC ATCGCCCGTG ACTCGCTGCC CCCCTACTCC
TGGCACTATG CGCCCTGGAC CAAGTGCTCG GCCCAGTGTG CAGGCGGTAG CCAGGTGCAG
GCGGTGGAGT GCCGCAACCA GCTGGACAGC TCCGCGGTCG CCCCCCACTA CTGCAGTGCC
CACAGCAAGC TGCCCAAAAG GCAGCGCGCC TGCAACACGG AGCCTTGCCC TCCAGACTGG
GTTGTAGGGA ACTGGTCGCT CTGCAGCCGC AGCTGCGATG CAGGCGTGCG CAGCCGCTCG
GTCGTGTGCC AGCGCCGCGT CTCTGCCGCG GAGGAGAAGG CGCTGGACGA CAGCGCATGC
CCGCAGCCGC GCCCACCTGT ACTGGAGGCC TGCCACGGCC CCACTTGCCC TCCGGAGTGG
GCGGCCCTCG ACTGGTCTGA GGTCAGCCGC CCCCTTCCTT CGCGCCCACT GGGATGCCCA
GGTGGGGTGT CCACGGAGAC GCCTCTGCGC GGTCTCCAGG TTAGCTGTCC CCTCCTCACT
TCGCACTGGG GCAGCACCCT GAGCACGAAA CGCCCCTTCC AACTGCAGTG CACCCCCAGC
TGCGGGCCGG GCCTCCGCCA CCGCGTGGTC CTTTGCAAGA GCGCAGACCA CCGCGCCACG
CTGCCCCCGG CGCACTGCTC ACCCGCCGCC AAGCCACCGG CCACCATGCG CTGCAACTTG
CGCCGCTGCC CCCCGGCCCG CTGGGTGGCT GGCGAGTGGG GTGAGTGCTC TGCACAGTGC
GGCGTCGGGC AGCGGCAGCG CTCGGTGCGC TGCACCAGCC ACACGGGCCA GGCGTCGCAC
GAGTGCACGG AGGCCCTGCG GCCGCCCACC ACGCAGCAGT GTGAGGCCAA GTGCGACAGC
CCAACCCCCG GGGACGGCCC TGAAGAGTGC AAGGATGTGA ACAAGGTCGC CTACTGCCCC
CTGGTGCTCA AATTTCAGTT CTGCAGCCGA GCCTACTTCC GCCAGATGTG CTGCAAAACC
TGCCATGGCC ACTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu72993
Accession Version XM_011528335.1
Sequence Information ORF Nucleotide Sequence (Length: 2028bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product A disintegrin and metalloproteinase with thrombospondin motifs 10 isoform X4
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_011295.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
ATGCAGATGA GCAATGCCGC TTTCAGCATG GAGTCAAATC GCGTCAGTGA GGTCTGCAGC 
GAGCTGTGGT GTCTGAGCAA GAGCAACCGG TGCATCACCA ACAGCATCCC GGCCGCCGAG
GGCACGCTGT GCCAGACGCA CACCATCGAC AAGGGGTGGT GCTACAAACG GGTCTGTGTC
CCCTTTGGGT CGCGCCCAGA GGGTGTGGAC GGAGCCTGGG GGCCGTGGAC TCCATGGGGC
GACTGCAGCC GGACCTGTGG CGGCGGCGTG TCCTCTTCTA GCCGTCACTG CGACAGCCCC
AGGCCAACCA TCGGGGGCAA GTACTGTCTG GGTGAGAGAA GGCGGCACCG CTCCTGCAAC
ACGGATGACT GTCCCCCTGG CTCCCAGGAC TTCAGAGAAG TGCAGTGTTC TGAATTTGAC
AGCATCCCTT TCCGTGGGAA ATTCTACAAG TGGAAAACGT ACCGGGGAGG GGGCGTGAAG
GCCTGCTCGC TCACGTGCCT AGCGGAAGGC TTCAACTTCT ACACGGAGAG GGCGGCAGCC
GTGGTGGACG GGACACCCTG CCGTCCAGAC ACGGTGGACA TTTGCGTCAG TGGCGAATGC
AAGCACGTGG GCTGCGACCG AGTCCTGGGC TCCGACCTGC GGGAGGACAA GTGCCGAGTG
TGTGGCGGTG ACGGCAGTGC CTGCGAGACC ATCGAGGGCG TCTTCAGCCC AGCCTCACCT
GGGGCCGGGT ACGAGGATGT CGTCTGGATT CCCAAAGGCT CCGTCCACAT CTTCATCCAG
GATCTGAACC TCTCTCTCAG TCACTTGGCC CTGAAGGGAG ACCAGGAGTC CCTGCTGCTG
GAGGGGCTGC CTGGGACCCC CCAGCCCCAC CGTCTGCCTC TAGCTGGGAC CACCTTTCAA
CTGCGACAGG GGCCAGACCA GGTCCAGAGC CTCGAAGCCC TGGGACCGAT TAATGCATCT
CTCATCGTCA TGGTGCTGGC CCGGACCGAG CTGCCTGCCC TCCGCTACCG CTTCAATGCC
CCCATCGCCC GTGACTCGCT GCCCCCCTAC TCCTGGCACT ATGCGCCCTG GACCAAGTGC
TCGGCCCAGT GTGCAGGCGG TAGCCAGGTG CAGGCGGTGG AGTGCCGCAA CCAGCTGGAC
AGCTCCGCGG TCGCCCCCCA CTACTGCAGT GCCCACAGCA AGCTGCCCAA AAGGCAGCGC
GCCTGCAACA CGGAGCCTTG CCCTCCAGAC TGGGTTGTAG GGAACTGGTC GCTCTGCAGC
CGCAGCTGCG ATGCAGGCGT GCGCAGCCGC TCGGTCGTGT GCCAGCGCCG CGTCTCTGCC
GCGGAGGAGA AGGCGCTGGA CGACAGCGCA TGCCCGCAGC CGCGCCCACC TGTACTGGAG
GCCTGCCACG GCCCCACTTG CCCTCCGGAG TGGGCGGCCC TCGACTGGTC TGAGGTCAGC
CGCCCCCTTC CTTCGCGCCC ACTGGGATGC CCAGGTGGGG TGTCCACGGA GACGCCTCTG
CGCGGTCTCC AGGTTAGCTG TCCCCTCCTC ACTTCGCACT GGGGCAGCAC CCTGAGCACG
AAACGCCCCT TCCAACTGCA GTGCACCCCC AGCTGCGGGC CGGGCCTCCG CCACCGCGTG
GTCCTTTGCA AGAGCGCAGA CCACCGCGCC ACGCTGCCCC CGGCGCACTG CTCACCCGCC
GCCAAGCCAC CGGCCACCAT GCGCTGCAAC TTGCGCCGCT GCCCCCCGGC CCGCTGGGTG
GCTGGCGAGT GGGGTGAGTG CTCTGCACAG TGCGGCGTCG GGCAGCGGCA GCGCTCGGTG
CGCTGCACCA GCCACACGGG CCAGGCGTCG CACGAGTGCA CGGAGGCCCT GCGGCCGCCC
ACCACGCAGC AGTGTGAGGC CAAGTGCGAC AGCCCAACCC CCGGGGACGG CCCTGAAGAG
TGCAAGGATG TGAACAAGGT CGCCTACTGC CCCCTGGTGC TCAAATTTCA GTTCTGCAGC
CGAGCCTACT TCCGCCAGAT GTGCTGCAAA ACCTGCCATG GCCACTAG
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqXP_011526637.1
CDS218..2245
Misc Feature(1)434..592(+)
Misc Feature(2)902..1240(+)
Misc Feature(3)1961..2095(+)
Misc Feature(4)2135..2233(+)
Translation
Position Chain Variation Link
339 339 a, g dbSNP:267606636
722 722 a, g dbSNP:148605664
751 751 a, g dbSNP:113579886
755 755 a, g dbSNP:202232012
884 884 a, g, t dbSNP:267606637
2126 2126 a, g dbSNP:80046653
2236 2236 g, t dbSNP:7252299
2567 2567 -, c dbSNP:150352175
2579 2579 g, t dbSNP:745911505
2692 2692 -, g dbSNP:527806324

Target ORF information:

RefSeq Version XM_011528335
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif, 10 (ADAMTS10), transcript variant X7, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011528335

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
ATGCAGATGA GCAATGCCGC TTTCAGCATG GAGTCAAATC GCGTCAGTGA GGTCTGCAGC 
GAGCTGTGGT GTCTGAGCAA GAGCAACCGG TGCATCACCA ACAGCATCCC GGCCGCCGAG
GGCACGCTGT GCCAGACGCA CACCATCGAC AAGGGGTGGT GCTACAAACG GGTCTGTGTC
CCCTTTGGGT CGCGCCCAGA GGGTGTGGAC GGAGCCTGGG GGCCGTGGAC TCCATGGGGC
GACTGCAGCC GGACCTGTGG CGGCGGCGTG TCCTCTTCTA GCCGTCACTG CGACAGCCCC
AGGCCAACCA TCGGGGGCAA GTACTGTCTG GGTGAGAGAA GGCGGCACCG CTCCTGCAAC
ACGGATGACT GTCCCCCTGG CTCCCAGGAC TTCAGAGAAG TGCAGTGTTC TGAATTTGAC
AGCATCCCTT TCCGTGGGAA ATTCTACAAG TGGAAAACGT ACCGGGGAGG GGGCGTGAAG
GCCTGCTCGC TCACGTGCCT AGCGGAAGGC TTCAACTTCT ACACGGAGAG GGCGGCAGCC
GTGGTGGACG GGACACCCTG CCGTCCAGAC ACGGTGGACA TTTGCGTCAG TGGCGAATGC
AAGCACGTGG GCTGCGACCG AGTCCTGGGC TCCGACCTGC GGGAGGACAA GTGCCGAGTG
TGTGGCGGTG ACGGCAGTGC CTGCGAGACC ATCGAGGGCG TCTTCAGCCC AGCCTCACCT
GGGGCCGGGT ACGAGGATGT CGTCTGGATT CCCAAAGGCT CCGTCCACAT CTTCATCCAG
GATCTGAACC TCTCTCTCAG TCACTTGGCC CTGAAGGGAG ACCAGGAGTC CCTGCTGCTG
GAGGGGCTGC CTGGGACCCC CCAGCCCCAC CGTCTGCCTC TAGCTGGGAC CACCTTTCAA
CTGCGACAGG GGCCAGACCA GGTCCAGAGC CTCGAAGCCC TGGGACCGAT TAATGCATCT
CTCATCGTCA TGGTGCTGGC CCGGACCGAG CTGCCTGCCC TCCGCTACCG CTTCAATGCC
CCCATCGCCC GTGACTCGCT GCCCCCCTAC TCCTGGCACT ATGCGCCCTG GACCAAGTGC
TCGGCCCAGT GTGCAGGCGG TAGCCAGGTG CAGGCGGTGG AGTGCCGCAA CCAGCTGGAC
AGCTCCGCGG TCGCCCCCCA CTACTGCAGT GCCCACAGCA AGCTGCCCAA AAGGCAGCGC
GCCTGCAACA CGGAGCCTTG CCCTCCAGAC TGGGTTGTAG GGAACTGGTC GCTCTGCAGC
CGCAGCTGCG ATGCAGGCGT GCGCAGCCGC TCGGTCGTGT GCCAGCGCCG CGTCTCTGCC
GCGGAGGAGA AGGCGCTGGA CGACAGCGCA TGCCCGCAGC CGCGCCCACC TGTACTGGAG
GCCTGCCACG GCCCCACTTG CCCTCCGGAG TGGGCGGCCC TCGACTGGTC TGAGGTCAGC
CGCCCCCTTC CTTCGCGCCC ACTGGGATGC CCAGGTGGGG TGTCCACGGA GACGCCTCTG
CGCGGTCTCC AGGTTAGCTG TCCCCTCCTC ACTTCGCACT GGGGCAGCAC CCTGAGCACG
AAACGCCCCT TCCAACTGCA GTGCACCCCC AGCTGCGGGC CGGGCCTCCG CCACCGCGTG
GTCCTTTGCA AGAGCGCAGA CCACCGCGCC ACGCTGCCCC CGGCGCACTG CTCACCCGCC
GCCAAGCCAC CGGCCACCAT GCGCTGCAAC TTGCGCCGCT GCCCCCCGGC CCGCTGGGTG
GCTGGCGAGT GGGGTGAGTG CTCTGCACAG TGCGGCGTCG GGCAGCGGCA GCGCTCGGTG
CGCTGCACCA GCCACACGGG CCAGGCGTCG CACGAGTGCA CGGAGGCCCT GCGGCCGCCC
ACCACGCAGC AGTGTGAGGC CAAGTGCGAC AGCCCAACCC CCGGGGACGG CCCTGAAGAG
TGCAAGGATG TGAACAAGGT CGCCTACTGC CCCCTGGTGC TCAAATTTCA GTTCTGCAGC
CGAGCCTACT TCCGCCAGAT GTGCTGCAAA ACCTGCCATG GCCACTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu72994
Accession Version XM_011528336.1
Sequence Information ORF Nucleotide Sequence (Length: 2022bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product A disintegrin and metalloproteinase with thrombospondin motifs 10 isoform X5
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_011295.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
ATGCAGATGA GCAATGCCGC TTTCAGCATG GAGTCAAATC GCGAGGTCTG CAGCGAGCTG 
TGGTGTCTGA GCAAGAGCAA CCGGTGCATC ACCAACAGCA TCCCGGCCGC CGAGGGCACG
CTGTGCCAGA CGCACACCAT CGACAAGGGG TGGTGCTACA AACGGGTCTG TGTCCCCTTT
GGGTCGCGCC CAGAGGGTGT GGACGGAGCC TGGGGGCCGT GGACTCCATG GGGCGACTGC
AGCCGGACCT GTGGCGGCGG CGTGTCCTCT TCTAGCCGTC ACTGCGACAG CCCCAGGCCA
ACCATCGGGG GCAAGTACTG TCTGGGTGAG AGAAGGCGGC ACCGCTCCTG CAACACGGAT
GACTGTCCCC CTGGCTCCCA GGACTTCAGA GAAGTGCAGT GTTCTGAATT TGACAGCATC
CCTTTCCGTG GGAAATTCTA CAAGTGGAAA ACGTACCGGG GAGGGGGCGT GAAGGCCTGC
TCGCTCACGT GCCTAGCGGA AGGCTTCAAC TTCTACACGG AGAGGGCGGC AGCCGTGGTG
GACGGGACAC CCTGCCGTCC AGACACGGTG GACATTTGCG TCAGTGGCGA ATGCAAGCAC
GTGGGCTGCG ACCGAGTCCT GGGCTCCGAC CTGCGGGAGG ACAAGTGCCG AGTGTGTGGC
GGTGACGGCA GTGCCTGCGA GACCATCGAG GGCGTCTTCA GCCCAGCCTC ACCTGGGGCC
GGGTACGAGG ATGTCGTCTG GATTCCCAAA GGCTCCGTCC ACATCTTCAT CCAGGATCTG
AACCTCTCTC TCAGTCACTT GGCCCTGAAG GGAGACCAGG AGTCCCTGCT GCTGGAGGGG
CTGCCTGGGA CCCCCCAGCC CCACCGTCTG CCTCTAGCTG GGACCACCTT TCAACTGCGA
CAGGGGCCAG ACCAGGTCCA GAGCCTCGAA GCCCTGGGAC CGATTAATGC ATCTCTCATC
GTCATGGTGC TGGCCCGGAC CGAGCTGCCT GCCCTCCGCT ACCGCTTCAA TGCCCCCATC
GCCCGTGACT CGCTGCCCCC CTACTCCTGG CACTATGCGC CCTGGACCAA GTGCTCGGCC
CAGTGTGCAG GCGGTAGCCA GGTGCAGGCG GTGGAGTGCC GCAACCAGCT GGACAGCTCC
GCGGTCGCCC CCCACTACTG CAGTGCCCAC AGCAAGCTGC CCAAAAGGCA GCGCGCCTGC
AACACGGAGC CTTGCCCTCC AGACTGGGTT GTAGGGAACT GGTCGCTCTG CAGCCGCAGC
TGCGATGCAG GCGTGCGCAG CCGCTCGGTC GTGTGCCAGC GCCGCGTCTC TGCCGCGGAG
GAGAAGGCGC TGGACGACAG CGCATGCCCG CAGCCGCGCC CACCTGTACT GGAGGCCTGC
CACGGCCCCA CTTGCCCTCC GGAGTGGGCG GCCCTCGACT GGTCTGAGGT CAGCCGCCCC
CTTCCTTCGC GCCCACTGGG ATGCCCAGGT GGGGTGTCCA CGGAGACGCC TCTGCGCGGT
CTCCAGGTTA GCTGTCCCCT CCTCACTTCG CACTGGGGCA GCACCCTGAG CACGAAACGC
CCCTTCCAAC TGCAGTGCAC CCCCAGCTGC GGGCCGGGCC TCCGCCACCG CGTGGTCCTT
TGCAAGAGCG CAGACCACCG CGCCACGCTG CCCCCGGCGC ACTGCTCACC CGCCGCCAAG
CCACCGGCCA CCATGCGCTG CAACTTGCGC CGCTGCCCCC CGGCCCGCTG GGTGGCTGGC
GAGTGGGGTG AGTGCTCTGC ACAGTGCGGC GTCGGGCAGC GGCAGCGCTC GGTGCGCTGC
ACCAGCCACA CGGGCCAGGC GTCGCACGAG TGCACGGAGG CCCTGCGGCC GCCCACCACG
CAGCAGTGTG AGGCCAAGTG CGACAGCCCA ACCCCCGGGG ACGGCCCTGA AGAGTGCAAG
GATGTGAACA AGGTCGCCTA CTGCCCCCTG GTGCTCAAAT TTCAGTTCTG CAGCCGAGCC
TACTTCCGCC AGATGTGCTG CAAAACCTGC CATGGCCACT AG
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqXP_011526638.1
CDS83..2104
Misc Feature(1)293..451(+)
Misc Feature(2)761..1099(+)
Misc Feature(3)1820..1954(+)
Misc Feature(4)1994..2092(+)
Translation
Position Chain Variation Link
198 198 a, g dbSNP:267606636
581 581 a, g dbSNP:148605664
610 610 a, g dbSNP:113579886
614 614 a, g dbSNP:202232012
743 743 a, g, t dbSNP:267606637
1985 1985 a, g dbSNP:80046653
2095 2095 g, t dbSNP:7252299
2426 2426 -, c dbSNP:150352175
2438 2438 g, t dbSNP:745911505
2551 2551 -, g dbSNP:527806324

Target ORF information:

RefSeq Version XM_011528336
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif, 10 (ADAMTS10), transcript variant X8, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011528336

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
ATGCAGATGA GCAATGCCGC TTTCAGCATG GAGTCAAATC GCGAGGTCTG CAGCGAGCTG 
TGGTGTCTGA GCAAGAGCAA CCGGTGCATC ACCAACAGCA TCCCGGCCGC CGAGGGCACG
CTGTGCCAGA CGCACACCAT CGACAAGGGG TGGTGCTACA AACGGGTCTG TGTCCCCTTT
GGGTCGCGCC CAGAGGGTGT GGACGGAGCC TGGGGGCCGT GGACTCCATG GGGCGACTGC
AGCCGGACCT GTGGCGGCGG CGTGTCCTCT TCTAGCCGTC ACTGCGACAG CCCCAGGCCA
ACCATCGGGG GCAAGTACTG TCTGGGTGAG AGAAGGCGGC ACCGCTCCTG CAACACGGAT
GACTGTCCCC CTGGCTCCCA GGACTTCAGA GAAGTGCAGT GTTCTGAATT TGACAGCATC
CCTTTCCGTG GGAAATTCTA CAAGTGGAAA ACGTACCGGG GAGGGGGCGT GAAGGCCTGC
TCGCTCACGT GCCTAGCGGA AGGCTTCAAC TTCTACACGG AGAGGGCGGC AGCCGTGGTG
GACGGGACAC CCTGCCGTCC AGACACGGTG GACATTTGCG TCAGTGGCGA ATGCAAGCAC
GTGGGCTGCG ACCGAGTCCT GGGCTCCGAC CTGCGGGAGG ACAAGTGCCG AGTGTGTGGC
GGTGACGGCA GTGCCTGCGA GACCATCGAG GGCGTCTTCA GCCCAGCCTC ACCTGGGGCC
GGGTACGAGG ATGTCGTCTG GATTCCCAAA GGCTCCGTCC ACATCTTCAT CCAGGATCTG
AACCTCTCTC TCAGTCACTT GGCCCTGAAG GGAGACCAGG AGTCCCTGCT GCTGGAGGGG
CTGCCTGGGA CCCCCCAGCC CCACCGTCTG CCTCTAGCTG GGACCACCTT TCAACTGCGA
CAGGGGCCAG ACCAGGTCCA GAGCCTCGAA GCCCTGGGAC CGATTAATGC ATCTCTCATC
GTCATGGTGC TGGCCCGGAC CGAGCTGCCT GCCCTCCGCT ACCGCTTCAA TGCCCCCATC
GCCCGTGACT CGCTGCCCCC CTACTCCTGG CACTATGCGC CCTGGACCAA GTGCTCGGCC
CAGTGTGCAG GCGGTAGCCA GGTGCAGGCG GTGGAGTGCC GCAACCAGCT GGACAGCTCC
GCGGTCGCCC CCCACTACTG CAGTGCCCAC AGCAAGCTGC CCAAAAGGCA GCGCGCCTGC
AACACGGAGC CTTGCCCTCC AGACTGGGTT GTAGGGAACT GGTCGCTCTG CAGCCGCAGC
TGCGATGCAG GCGTGCGCAG CCGCTCGGTC GTGTGCCAGC GCCGCGTCTC TGCCGCGGAG
GAGAAGGCGC TGGACGACAG CGCATGCCCG CAGCCGCGCC CACCTGTACT GGAGGCCTGC
CACGGCCCCA CTTGCCCTCC GGAGTGGGCG GCCCTCGACT GGTCTGAGGT CAGCCGCCCC
CTTCCTTCGC GCCCACTGGG ATGCCCAGGT GGGGTGTCCA CGGAGACGCC TCTGCGCGGT
CTCCAGGTTA GCTGTCCCCT CCTCACTTCG CACTGGGGCA GCACCCTGAG CACGAAACGC
CCCTTCCAAC TGCAGTGCAC CCCCAGCTGC GGGCCGGGCC TCCGCCACCG CGTGGTCCTT
TGCAAGAGCG CAGACCACCG CGCCACGCTG CCCCCGGCGC ACTGCTCACC CGCCGCCAAG
CCACCGGCCA CCATGCGCTG CAACTTGCGC CGCTGCCCCC CGGCCCGCTG GGTGGCTGGC
GAGTGGGGTG AGTGCTCTGC ACAGTGCGGC GTCGGGCAGC GGCAGCGCTC GGTGCGCTGC
ACCAGCCACA CGGGCCAGGC GTCGCACGAG TGCACGGAGG CCCTGCGGCC GCCCACCACG
CAGCAGTGTG AGGCCAAGTG CGACAGCCCA ACCCCCGGGG ACGGCCCTGA AGAGTGCAAG
GATGTGAACA AGGTCGCCTA CTGCCCCCTG GTGCTCAAAT TTCAGTTCTG CAGCCGAGCC
TACTTCCGCC AGATGTGCTG CAAAACCTGC CATGGCCACT AG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu20510
Accession Version NM_030957.3
Sequence Information ORF Nucleotide Sequence (Length: 3312bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product A disintegrin and metalloproteinase with thrombospondin motifs 10 isoform 1 preproprotein
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from CN431169.1, AB209515.1, AF163762.1, BC029308.1, AC130469.2, AK131414.1 and BF510205.1. This sequence is a reference standard in the RefSeqGene project. On Aug 31, 2013 this sequence version replaced gi:56121814. Summary: This gene belongs to the ADAMTS (a disintegrin and metalloproteinase domain with thrombospondin type-1 motifs) family of zinc-dependent proteases. ADAMTS proteases are complex secreted enzymes containing a prometalloprotease domain of the reprolysin type attached to an ancillary domain with a highly conserved structure that includes at least one thrombospondin type 1 repeat. They have been demonstrated to have important roles in connective tissue organization, coagulation, inflammation, arthritis, angiogenesis and cell migration. The product of this gene plays a major role in growth and in skin, lens, and heart development. It is also a candidate gene for autosomal recessive Weill-Marchesani syndrome. [provided by RefSeq, Jul 2008]. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##RefSeq-Attributes-START## inferred exon combination :: based on alignments, homology ##RefSeq-Attributes-END## ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
3061
3121
3181
3241
3301
ATGGCTCCCG CCTGCCAGAT CCTCCGCTGG GCCCTCGCCC TGGGGCTGGG CCTCATGTTC 
GAGGTCACGC ACGCCTTCCG GTCTCAAGAT GAGTTCCTGT CCAGTCTGGA GAGCTATGAG
ATCGCCTTCC CCACCCGCGT GGACCACAAC GGGGCACTGC TGGCCTTCTC GCCACCTCCT
CCCCGGAGGC AGCGCCGCGG CACGGGGGCC ACAGCCGAGT CCCGCCTCTT CTACAAAGTG
GCCTCGCCCA GCACCCACTT CCTGCTGAAC CTGACCCGCA GCTCCCGTCT ACTGGCAGGG
CACGTCTCCG TGGAGTACTG GACACGGGAG GGCCTGGCCT GGCAGAGGGC GGCCCGGCCC
CACTGCCTCT ACGCTGGTCA CCTGCAGGGC CAGGCCAGCA GCTCCCATGT GGCCATCAGC
ACCTGTGGAG GCCTGCACGG CCTGATCGTG GCAGACGAGG AAGAGTACCT GATTGAGCCC
CTGCACGGTG GGCCCAAGGG TTCTCGGAGC CCGGAGGAAA GTGGACCACA TGTGGTGTAC
AAGCGTTCCT CTCTGCGTCA CCCCCACCTG GACACAGCCT GTGGAGTGAG AGATGAGAAA
CCGTGGAAAG GGCGGCCATG GTGGCTGCGG ACCTTGAAGC CACCGCCTGC CAGGCCCCTG
GGGAATGAAA CAGAGCGTGG CCAGCCAGGC CTGAAGCGAT CGGTCAGCCG AGAGCGCTAC
GTGGAGACCC TGGTGGTGGC TGACAAGATG ATGGTGGCCT ATCACGGGCG CCGGGATGTG
GAGCAGTATG TCCTGGCCAT CATGAACATT GTTGCCAAAC TTTTCCAGGA CTCGAGTCTG
GGAAGCACCG TTAACATCCT CGTAACTCGC CTCATCCTGC TCACGGAGGA CCAGCCCACT
CTGGAGATCA CCCACCATGC CGGGAAGTCC CTGGACAGCT TCTGTAAGTG GCAGAAATCC
ATCGTGAACC ACAGCGGCCA TGGCAATGCC ATTCCAGAGA ACGGTGTGGC TAACCATGAC
ACAGCAGTGC TCATCACACG CTATGACATC TGCATCTACA AGAACAAACC CTGCGGCACA
CTAGGCCTGG CCCCGGTGGG CGGAATGTGT GAGCGCGAGA GAAGCTGCAG CGTCAATGAG
GACATTGGCC TGGCCACAGC GTTCACCATT GCCCACGAGA TCGGGCACAC ATTCGGCATG
AACCATGACG GCGTGGGAAA CAGCTGTGGG GCCCGTGGTC AGGACCCAGC CAAGCTCATG
GCTGCCCACA TTACCATGAA GACCAACCCA TTCGTGTGGT CATCCTGCAG CCGTGACTAC
ATCACCAGCT TTCTAGACTC GGGCCTGGGG CTCTGCCTGA ACAACCGGCC CCCCAGACAG
GACTTTGTGT ACCCGACAGT GGCACCGGGC CAAGCCTACG ATGCAGATGA GCAATGCCGC
TTTCAGCATG GAGTCAAATC GCGTCAGTGT AAATACGGGG AGGTCTGCAG CGAGCTGTGG
TGTCTGAGCA AGAGCAACCG GTGCATCACC AACAGCATCC CGGCCGCCGA GGGCACGCTG
TGCCAGACGC ACACCATCGA CAAGGGGTGG TGCTACAAAC GGGTCTGTGT CCCCTTTGGG
TCGCGCCCAG AGGGTGTGGA CGGAGCCTGG GGGCCGTGGA CTCCATGGGG CGACTGCAGC
CGGACCTGTG GCGGCGGCGT GTCCTCTTCT AGCCGTCACT GCGACAGCCC CAGGCCAACC
ATCGGGGGCA AGTACTGTCT GGGTGAGAGA AGGCGGCACC GCTCCTGCAA CACGGATGAC
TGTCCCCCTG GCTCCCAGGA CTTCAGAGAA GTGCAGTGTT CTGAATTTGA CAGCATCCCT
TTCCGTGGGA AATTCTACAA GTGGAAAACG TACCGGGGAG GGGGCGTGAA GGCCTGCTCG
CTCACGTGCC TAGCGGAAGG CTTCAACTTC TACACGGAGA GGGCGGCAGC CGTGGTGGAC
GGGACACCCT GCCGTCCAGA CACGGTGGAC ATTTGCGTCA GTGGCGAATG CAAGCACGTG
GGCTGCGACC GAGTCCTGGG CTCCGACCTG CGGGAGGACA AGTGCCGAGT GTGTGGCGGT
GACGGCAGTG CCTGCGAGAC CATCGAGGGC GTCTTCAGCC CAGCCTCACC TGGGGCCGGG
TACGAGGATG TCGTCTGGAT TCCCAAAGGC TCCGTCCACA TCTTCATCCA GGATCTGAAC
CTCTCTCTCA GTCACTTGGC CCTGAAGGGA GACCAGGAGT CCCTGCTGCT GGAGGGGCTG
CCTGGGACCC CCCAGCCCCA CCGTCTGCCT CTAGCTGGGA CCACCTTTCA ACTGCGACAG
GGGCCAGACC AGGTCCAGAG CCTCGAAGCC CTGGGACCGA TTAATGCATC TCTCATCGTC
ATGGTGCTGG CCCGGACCGA GCTGCCTGCC CTCCGCTACC GCTTCAATGC CCCCATCGCC
CGTGACTCGC TGCCCCCCTA CTCCTGGCAC TATGCGCCCT GGACCAAGTG CTCGGCCCAG
TGTGCAGGCG GTAGCCAGGT GCAGGCGGTG GAGTGCCGCA ACCAGCTGGA CAGCTCCGCG
GTCGCCCCCC ACTACTGCAG TGCCCACAGC AAGCTGCCCA AAAGGCAGCG CGCCTGCAAC
ACGGAGCCTT GCCCTCCAGA CTGGGTTGTA GGGAACTGGT CGCTCTGCAG CCGCAGCTGC
GATGCAGGCG TGCGCAGCCG CTCGGTCGTG TGCCAGCGCC GCGTCTCTGC CGCGGAGGAG
AAGGCGCTGG ACGACAGCGC ATGCCCGCAG CCGCGCCCAC CTGTACTGGA GGCCTGCCAC
GGCCCCACTT GCCCTCCGGA GTGGGCGGCC CTCGACTGGT CTGAGTGCAC CCCCAGCTGC
GGGCCGGGCC TCCGCCACCG CGTGGTCCTT TGCAAGAGCG CAGACCACCG CGCCACGCTG
CCCCCGGCGC ACTGCTCACC CGCCGCCAAG CCACCGGCCA CCATGCGCTG CAACTTGCGC
CGCTGCCCCC CGGCCCGCTG GGTGGCTGGC GAGTGGGGTG AGTGCTCTGC ACAGTGCGGC
GTCGGGCAGC GGCAGCGCTC GGTGCGCTGC ACCAGCCACA CGGGCCAGGC GTCGCACGAG
TGCACGGAGG CCCTGCGGCC GCCCACCACG CAGCAGTGTG AGGCCAAGTG CGACAGCCCA
ACCCCCGGGG ACGGCCCTGA AGAGTGCAAG GATGTGAACA AGGTCGCCTA CTGCCCCCTG
GTGCTCAAAT TTCAGTTCTG CAGCCGAGCC TACTTCCGCC AGATGTGCTG CAAAACCTGC
CATGGCCACT AG
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_112219.3
CDS307..3618
Misc Feature(1)421..846(+)
Misc Feature(2)1021..1677(+)
Misc Feature(3)1021..1668(+)
Misc Feature(4)1480..1512(+)
Misc Feature(5)1954..2112(+)
Misc Feature(6)2422..2790(+)
Misc Feature(7)2422..2760(+)
Misc Feature(8)2791..2961(+)
Misc Feature(9)3160..3315(+)
Misc Feature(10)3334..3468(+)
Misc Feature(11)3508..3606(+)
Exon (1)1..92
Gene:ADAMTS10
Gene Synonym:
Exon (2)93..207
Gene:ADAMTS10
Gene Synonym:
Exon (3)208..394
Gene:ADAMTS10
Gene Synonym:
Exon (4)395..741
Gene:ADAMTS10
Gene Synonym:
Exon (5)742..898
Gene:ADAMTS10
Gene Synonym:
Exon (6)899..1116
Gene:ADAMTS10
Gene Synonym:
Exon (7)1117..1200
Gene:ADAMTS10
Gene Synonym:
Exon (8)1201..1346
Gene:ADAMTS10
Gene Synonym:
Exon (9)1347..1390
Gene:ADAMTS10
Gene Synonym:
Exon (10)1391..1496
Gene:ADAMTS10
Gene Synonym:
Exon (11)1497..1643
Gene:ADAMTS10
Gene Synonym:
Exon (12)1644..1785
Gene:ADAMTS10
Gene Synonym:
Exon (13)1786..1893
Gene:ADAMTS10
Gene Synonym:
Exon (14)1894..2039
Gene:ADAMTS10
Gene Synonym:
Exon (15)2040..2103
Gene:ADAMTS10
Gene Synonym:
Exon (16)2104..2206
Gene:ADAMTS10
Gene Synonym:
Exon (17)2207..2340
Gene:ADAMTS10
Gene Synonym:
Exon (18)2341..2464
Gene:ADAMTS10
Gene Synonym:
Exon (19)2465..2545
Gene:ADAMTS10
Gene Synonym:
Exon (20)2546..2709
Gene:ADAMTS10
Gene Synonym:
Exon (21)2710..2836
Gene:ADAMTS10
Gene Synonym:
Exon (22)2837..2966
Gene:ADAMTS10
Gene Synonym:
Exon (23)2967..3171
Gene:ADAMTS10
Gene Synonym:
Exon (24)3172..3348
Gene:ADAMTS10
Gene Synonym:
Exon (25)3349..3508
Gene:ADAMTS10
Gene Synonym:
Exon (26)3509..4271
Gene:ADAMTS10
Gene Synonym:
Translation
Position Chain Variation Link
379 379 a, g dbSNP:121434358
385 385 a, c, t dbSNP:111234410
662 662 a, c, g dbSNP:3814291
707 707 c, g dbSNP:7255721
1015 1015 c, t dbSNP:121434357
1074 1074 g, t dbSNP:200589780
1084 1084 a, g dbSNP:756947226
1258 1258 c, t dbSNP:121434359
1304 1304 a, c dbSNP:775640275
1366 1366 a, g dbSNP:759348240
1859 1859 a, g dbSNP:267606636
2242 2242 a, g dbSNP:148605664
2271 2271 a, g dbSNP:113579886
2275 2275 a, g dbSNP:202232012
2404 2404 a, g, t dbSNP:267606637
3499 3499 a, g dbSNP:80046653
3609 3609 g, t dbSNP:7252299
3940 3940 -, c dbSNP:150352175
3952 3952 g, t dbSNP:745911505
4065 4065 -, g dbSNP:527806324

Target ORF information:

RefSeq Version NM_030957
Organism Homo sapiens (human)
Definition Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif, 10 (ADAMTS10), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_030957

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
3061
3121
3181
3241
3301
ATGGCTCCCG CCTGCCAGAT CCTCCGCTGG GCCCTCGCCC TGGGGCTGGG CCTCATGTTC 
GAGGTCACGC ACGCCTTCCG GTCTCAAGAT GAGTTCCTGT CCAGTCTGGA GAGCTATGAG
ATCGCCTTCC CCACCCGCGT GGACCACAAC GGGGCACTGC TGGCCTTCTC GCCACCTCCT
CCCCGGAGGC AGCGCCGCGG CACGGGGGCC ACAGCCGAGT CCCGCCTCTT CTACAAAGTG
GCCTCGCCCA GCACCCACTT CCTGCTGAAC CTGACCCGCA GCTCCCGTCT ACTGGCAGGG
CACGTCTCCG TGGAGTACTG GACACGGGAG GGCCTGGCCT GGCAGAGGGC GGCCCGGCCC
CACTGCCTCT ACGCTGGTCA CCTGCAGGGC CAGGCCAGCA GCTCCCATGT GGCCATCAGC
ACCTGTGGAG GCCTGCACGG CCTGATCGTG GCAGACGAGG AAGAGTACCT GATTGAGCCC
CTGCACGGTG GGCCCAAGGG TTCTCGGAGC CCGGAGGAAA GTGGACCACA TGTGGTGTAC
AAGCGTTCCT CTCTGCGTCA CCCCCACCTG GACACAGCCT GTGGAGTGAG AGATGAGAAA
CCGTGGAAAG GGCGGCCATG GTGGCTGCGG ACCTTGAAGC CACCGCCTGC CAGGCCCCTG
GGGAATGAAA CAGAGCGTGG CCAGCCAGGC CTGAAGCGAT CGGTCAGCCG AGAGCGCTAC
GTGGAGACCC TGGTGGTGGC TGACAAGATG ATGGTGGCCT ATCACGGGCG CCGGGATGTG
GAGCAGTATG TCCTGGCCAT CATGAACATT GTTGCCAAAC TTTTCCAGGA CTCGAGTCTG
GGAAGCACCG TTAACATCCT CGTAACTCGC CTCATCCTGC TCACGGAGGA CCAGCCCACT
CTGGAGATCA CCCACCATGC CGGGAAGTCC CTGGACAGCT TCTGTAAGTG GCAGAAATCC
ATCGTGAACC ACAGCGGCCA TGGCAATGCC ATTCCAGAGA ACGGTGTGGC TAACCATGAC
ACAGCAGTGC TCATCACACG CTATGACATC TGCATCTACA AGAACAAACC CTGCGGCACA
CTAGGCCTGG CCCCGGTGGG CGGAATGTGT GAGCGCGAGA GAAGCTGCAG CGTCAATGAG
GACATTGGCC TGGCCACAGC GTTCACCATT GCCCACGAGA TCGGGCACAC ATTCGGCATG
AACCATGACG GCGTGGGAAA CAGCTGTGGG GCCCGTGGTC AGGACCCAGC CAAGCTCATG
GCTGCCCACA TTACCATGAA GACCAACCCA TTCGTGTGGT CATCCTGCAG CCGTGACTAC
ATCACCAGCT TTCTAGACTC GGGCCTGGGG CTCTGCCTGA ACAACCGGCC CCCCAGACAG
GACTTTGTGT ACCCGACAGT GGCACCGGGC CAAGCCTACG ATGCAGATGA GCAATGCCGC
TTTCAGCATG GAGTCAAATC GCGTCAGTGT AAATACGGGG AGGTCTGCAG CGAGCTGTGG
TGTCTGAGCA AGAGCAACCG GTGCATCACC AACAGCATCC CGGCCGCCGA GGGCACGCTG
TGCCAGACGC ACACCATCGA CAAGGGGTGG TGCTACAAAC GGGTCTGTGT CCCCTTTGGG
TCGCGCCCAG AGGGTGTGGA CGGAGCCTGG GGGCCGTGGA CTCCATGGGG CGACTGCAGC
CGGACCTGTG GCGGCGGCGT GTCCTCTTCT AGCCGTCACT GCGACAGCCC CAGGCCAACC
ATCGGGGGCA AGTACTGTCT GGGTGAGAGA AGGCGGCACC GCTCCTGCAA CACGGATGAC
TGTCCCCCTG GCTCCCAGGA CTTCAGAGAA GTGCAGTGTT CTGAATTTGA CAGCATCCCT
TTCCGTGGGA AATTCTACAA GTGGAAAACG TACCGGGGAG GGGGCGTGAA GGCCTGCTCG
CTCACGTGCC TAGCGGAAGG CTTCAACTTC TACACGGAGA GGGCGGCAGC CGTGGTGGAC
GGGACACCCT GCCGTCCAGA CACGGTGGAC ATTTGCGTCA GTGGCGAATG CAAGCACGTG
GGCTGCGACC GAGTCCTGGG CTCCGACCTG CGGGAGGACA AGTGCCGAGT GTGTGGCGGT
GACGGCAGTG CCTGCGAGAC CATCGAGGGC GTCTTCAGCC CAGCCTCACC TGGGGCCGGG
TACGAGGATG TCGTCTGGAT TCCCAAAGGC TCCGTCCACA TCTTCATCCA GGATCTGAAC
CTCTCTCTCA GTCACTTGGC CCTGAAGGGA GACCAGGAGT CCCTGCTGCT GGAGGGGCTG
CCTGGGACCC CCCAGCCCCA CCGTCTGCCT CTAGCTGGGA CCACCTTTCA ACTGCGACAG
GGGCCAGACC AGGTCCAGAG CCTCGAAGCC CTGGGACCGA TTAATGCATC TCTCATCGTC
ATGGTGCTGG CCCGGACCGA GCTGCCTGCC CTCCGCTACC GCTTCAATGC CCCCATCGCC
CGTGACTCGC TGCCCCCCTA CTCCTGGCAC TATGCGCCCT GGACCAAGTG CTCGGCCCAG
TGTGCAGGCG GTAGCCAGGT GCAGGCGGTG GAGTGCCGCA ACCAGCTGGA CAGCTCCGCG
GTCGCCCCCC ACTACTGCAG TGCCCACAGC AAGCTGCCCA AAAGGCAGCG CGCCTGCAAC
ACGGAGCCTT GCCCTCCAGA CTGGGTTGTA GGGAACTGGT CGCTCTGCAG CCGCAGCTGC
GATGCAGGCG TGCGCAGCCG CTCGGTCGTG TGCCAGCGCC GCGTCTCTGC CGCGGAGGAG
AAGGCGCTGG ACGACAGCGC ATGCCCGCAG CCGCGCCCAC CTGTACTGGA GGCCTGCCAC
GGCCCCACTT GCCCTCCGGA GTGGGCGGCC CTCGACTGGT CTGAGTGCAC CCCCAGCTGC
GGGCCGGGCC TCCGCCACCG CGTGGTCCTT TGCAAGAGCG CAGACCACCG CGCCACGCTG
CCCCCGGCGC ACTGCTCACC CGCCGCCAAG CCACCGGCCA CCATGCGCTG CAACTTGCGC
CGCTGCCCCC CGGCCCGCTG GGTGGCTGGC GAGTGGGGTG AGTGCTCTGC ACAGTGCGGC
GTCGGGCAGC GGCAGCGCTC GGTGCGCTGC ACCAGCCACA CGGGCCAGGC GTCGCACGAG
TGCACGGAGG CCCTGCGGCC GCCCACCACG CAGCAGTGTG AGGCCAAGTG CGACAGCCCA
ACCCCCGGGG ACGGCCCTGA AGAGTGCAAG GATGTGAACA AGGTCGCCTA CTGCCCCCTG
GTGCTCAAAT TTCAGTTCTG CAGCCGAGCC TACTTCCGCC AGATGTGCTG CAAAACCTGC
CATGGCCACT AG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu20533
Accession Version NM_001282352.1
Sequence Information ORF Nucleotide Sequence (Length: 1773bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product A disintegrin and metalloproteinase with thrombospondin motifs 10 isoform 2
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK131414.1, AF163762.1, BC029308.1, AC130469.2 and BF510205.1. On or before Aug 31, 2013 this sequence version replaced gi:530427548, gi:530432893. Summary: This gene belongs to the ADAMTS (a disintegrin and metalloproteinase domain with thrombospondin type-1 motifs) family of zinc-dependent proteases. ADAMTS proteases are complex secreted enzymes containing a prometalloprotease domain of the reprolysin type attached to an ancillary domain with a highly conserved structure that includes at least one thrombospondin type 1 repeat. They have been demonstrated to have important roles in connective tissue organization, coagulation, inflammation, arthritis, angiogenesis and cell migration. The product of this gene plays a major role in growth and in skin, lens, and heart development. It is also a candidate gene for autosomal recessive Weill-Marchesani syndrome. [provided by RefSeq, Jul 2008]. Transcript Variant: This variant (2) lacks several exons, uses an alternate 5'-terminal exon, and initiates translation at an alternate start codon, compared to variant 1. The encoded isoform (2) has a shorter and distinct N-terminus, compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK131414.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
ATGGGGCCGA CGAGTGTCCT CCGGGCTGGA CTCACTCCTT CCTGTCTCCC CCCACCCAGT 
GGTGCTACAA ACGGGTCTGT GTCCCCTTTG GGTCGCGCCC AGAGGGTGTG GACGGAGCCT
GGGGGCCGTG GACTCCATGG GGCGACTGCA GCCGGACCTG TGGCGGCGGC GTGTCCTCTT
CTAGCCGTCA CTGCGACAGC CCCAGGCCAA CCATCGGGGG CAAGTACTGT CTGGGTGAGA
GAAGGCGGCA CCGCTCCTGC AACACGGATG ACTGTCCCCC TGGCTCCCAG GACTTCAGAG
AAGTGCAGTG TTCTGAATTT GACAGCATCC CTTTCCGTGG GAAATTCTAC AAGTGGAAAA
CGTACCGGGG AGGCCTGCTC GCTCACGTGC CTAGCGGAAG GCTTCAACTT CTACACGGAG
AGGGCGGCAG CCGTGGTGGA CGGGACACCC TGCCGTCCAG ACACGGTGGA CATTTGCGTC
AGTGGCGAAT GCAAGCACGT GGGCTGCGAC CGAGTCCTGG GCTCCGACCT GCGGGAGGAC
AAGTGCCGAG TGTGTGGCGG TGACGGCAGT GCCTGCGAGA CCATCGAGGG CGTCTTCAGC
CCAGCCTCAC CTGGGGCCGG GTACGAGGAT GTCGTCTGGA TTCCCAAAGG CTCCGTCCAC
ATCTTCATCC AGGATCTGAA CCTCTCTCTC AGTCACTTGG CCCTGAAGGG AGACCAGGAG
TCCCTGCTGC TGGAGGGGCT GCCTGGGACC CCCCAGCCCC ACCGTCTGCC TCTAGCTGGG
ACCACCTTTC AACTGCGACA GGGGCCAGAC CAGGTCCAGA GCCTCGAAGC CCTGGGACCG
ATTAATGCAT CTCTCATCGT CATGGTGCTG GCCCGGACCG AGCTGCCTGC CCTCCGCTAC
CGCTTCAATG CCCCCATCGC CCGTGACTCG CTGCCCCCCT ACTCCTGGCA CTATGCGCCC
TGGACCAAGT GCTCGGCCCA GTGTGCAGGC GGTAGCCAGG TGCAGGCGGT GGAGTGCCGC
AACCAGCTGG ACAGCTCCGC GGTCGCCCCC CACTACTGCA GTGCCCACAG CAAGCTGCCC
AAAAGGCAGC GCGCCTGCAA CACGGAGCCT TGCCCTCCAG ACTGGGTTGT AGGGAACTGG
TCGCTCTGCA GCCGCAGCTG CGATGCAGGC GTGCGCAGCC GCTCGGTCGT GTGCCAGCGC
CGCGTCTCTG CCGCGGAGGA GAAGGCGCTG GACGACAGCG CATGCCCGCA GCCGCGCCCA
CCTGTACTGG AGGCCTGCCA CGGCCCCACT TGCCCTCCGG AGTGGGCGGC CCTCGACTGG
TCTGAGTGCA CCCCCAGCTG CGGGCCGGGC CTCCGCCACC GCGTGGTCCT TTGCAAGAGC
GCAGACCACC GCGCCACGCT GCCCCCGGCG CACTGCTCAC CCGCCGCCAA GCCACCGGCC
ACCATGCGCT GCAACTTGCG CCGCTGCCCC CCGGCCCGCT GGGTGGCTGG CGAGTGGGGT
GAGTGCTCTG CACAGTGCGG CGTCGGGCAG CGGCAGCGCT CGGTGCGCTG CACCAGCCAC
ACGGGCCAGG CGTCGCACGA GTGCACGGAG GCCCTGCGGC CGCCCACCAC GCAGCAGTGT
GAGGCCAAGT GCGACAGCCC AACCCCCGGG GACGGCCCTG AAGAGTGCAA GGATGTGAAC
AAGGTCGCCT ACTGCCCCCT GGTGCTCAAA TTTCAGTTCT GCAGCCGAGC CTACTTCCGC
CAGATGTGCT GCAAAACCTG CCATGGCCAC TAG
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_001269281.1
CDS35..1807
Misc Feature(1)611..949(+)
Misc Feature(2)1349..1504(+)
Misc Feature(3)1523..1657(+)
Misc Feature(4)1697..1795(+)
Exon (1)1..239
Gene:ADAMTS10
Gene Synonym:
Exon (2)240..303
Gene:ADAMTS10
Gene Synonym:
Exon (3)304..406
Gene:ADAMTS10
Gene Synonym:
Exon (4)407..529
Gene:ADAMTS10
Gene Synonym:
Exon (5)530..653
Gene:ADAMTS10
Gene Synonym:
Exon (6)654..734
Gene:ADAMTS10
Gene Synonym:
Exon (7)735..898
Gene:ADAMTS10
Gene Synonym:
Exon (8)899..1025
Gene:ADAMTS10
Gene Synonym:
Exon (9)1026..1155
Gene:ADAMTS10
Gene Synonym:
Exon (10)1156..1360
Gene:ADAMTS10
Gene Synonym:
Exon (11)1361..1537
Gene:ADAMTS10
Gene Synonym:
Exon (12)1538..1697
Gene:ADAMTS10
Gene Synonym:
Exon (13)1698..2460
Gene:ADAMTS10
Gene Synonym:
Translation
Position Chain Variation Link
56 56 c, t dbSNP:73922162
83 83 c, t dbSNP:112970413
431 431 a, g dbSNP:148605664
460 460 a, g dbSNP:113579886
464 464 a, g dbSNP:202232012
593 593 a, g, t dbSNP:267606637
1688 1688 a, g dbSNP:80046653
1798 1798 g, t dbSNP:7252299
2129 2129 -, c dbSNP:150352175
2141 2141 g, t dbSNP:745911505
2254 2254 -, g dbSNP:527806324

Target ORF information:

RefSeq Version NM_001282352
Organism Homo sapiens (human)
Definition Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif, 10 (ADAMTS10), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001282352

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
ATGGGGCCGA CGAGTGTCCT CCGGGCTGGA CTCACTCCTT CCTGTCTCCC CCCACCCAGT 
GGTGCTACAA ACGGGTCTGT GTCCCCTTTG GGTCGCGCCC AGAGGGTGTG GACGGAGCCT
GGGGGCCGTG GACTCCATGG GGCGACTGCA GCCGGACCTG TGGCGGCGGC GTGTCCTCTT
CTAGCCGTCA CTGCGACAGC CCCAGGCCAA CCATCGGGGG CAAGTACTGT CTGGGTGAGA
GAAGGCGGCA CCGCTCCTGC AACACGGATG ACTGTCCCCC TGGCTCCCAG GACTTCAGAG
AAGTGCAGTG TTCTGAATTT GACAGCATCC CTTTCCGTGG GAAATTCTAC AAGTGGAAAA
CGTACCGGGG AGGCCTGCTC GCTCACGTGC CTAGCGGAAG GCTTCAACTT CTACACGGAG
AGGGCGGCAG CCGTGGTGGA CGGGACACCC TGCCGTCCAG ACACGGTGGA CATTTGCGTC
AGTGGCGAAT GCAAGCACGT GGGCTGCGAC CGAGTCCTGG GCTCCGACCT GCGGGAGGAC
AAGTGCCGAG TGTGTGGCGG TGACGGCAGT GCCTGCGAGA CCATCGAGGG CGTCTTCAGC
CCAGCCTCAC CTGGGGCCGG GTACGAGGAT GTCGTCTGGA TTCCCAAAGG CTCCGTCCAC
ATCTTCATCC AGGATCTGAA CCTCTCTCTC AGTCACTTGG CCCTGAAGGG AGACCAGGAG
TCCCTGCTGC TGGAGGGGCT GCCTGGGACC CCCCAGCCCC ACCGTCTGCC TCTAGCTGGG
ACCACCTTTC AACTGCGACA GGGGCCAGAC CAGGTCCAGA GCCTCGAAGC CCTGGGACCG
ATTAATGCAT CTCTCATCGT CATGGTGCTG GCCCGGACCG AGCTGCCTGC CCTCCGCTAC
CGCTTCAATG CCCCCATCGC CCGTGACTCG CTGCCCCCCT ACTCCTGGCA CTATGCGCCC
TGGACCAAGT GCTCGGCCCA GTGTGCAGGC GGTAGCCAGG TGCAGGCGGT GGAGTGCCGC
AACCAGCTGG ACAGCTCCGC GGTCGCCCCC CACTACTGCA GTGCCCACAG CAAGCTGCCC
AAAAGGCAGC GCGCCTGCAA CACGGAGCCT TGCCCTCCAG ACTGGGTTGT AGGGAACTGG
TCGCTCTGCA GCCGCAGCTG CGATGCAGGC GTGCGCAGCC GCTCGGTCGT GTGCCAGCGC
CGCGTCTCTG CCGCGGAGGA GAAGGCGCTG GACGACAGCG CATGCCCGCA GCCGCGCCCA
CCTGTACTGG AGGCCTGCCA CGGCCCCACT TGCCCTCCGG AGTGGGCGGC CCTCGACTGG
TCTGAGTGCA CCCCCAGCTG CGGGCCGGGC CTCCGCCACC GCGTGGTCCT TTGCAAGAGC
GCAGACCACC GCGCCACGCT GCCCCCGGCG CACTGCTCAC CCGCCGCCAA GCCACCGGCC
ACCATGCGCT GCAACTTGCG CCGCTGCCCC CCGGCCCGCT GGGTGGCTGG CGAGTGGGGT
GAGTGCTCTG CACAGTGCGG CGTCGGGCAG CGGCAGCGCT CGGTGCGCTG CACCAGCCAC
ACGGGCCAGG CGTCGCACGA GTGCACGGAG GCCCTGCGGC CGCCCACCAC GCAGCAGTGT
GAGGCCAAGT GCGACAGCCC AACCCCCGGG GACGGCCCTG AAGAGTGCAA GGATGTGAAC
AAGGTCGCCT ACTGCCCCCT GGTGCTCAAA TTTCAGTTCT GCAGCCGAGC CTACTTCCGC
CAGATGTGCT GCAAAACCTG CCATGGCCAC TAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.