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QTRT1 queuine tRNA-ribosyltransferase 1 [Homo sapiens (human)]

Gene Symbol QTRT1
Entrez Gene ID 81890
Full Name queuine tRNA-ribosyltransferase 1
Synonyms FP3235, TGT, TGUT
General protein information
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

19

19p13.3

Summary This gene encodes the catalytic subunit of tRNA-guanine transglycosylase. tRNA-guanine transglycosylase is a heterodimeric enzyme complex that plays a critical role in tRNA modification by synthesizing the 7-deazaguanosine queuosine, which is found in tRNAs that code for asparagine, aspartic acid, histidine and tyrosine. A pseudogene of this gene is located on the long arm of chromosome X. [provided by RefSeq, Feb 2012]. lac of sum
Disorder MIM:

609615

Disorder Html:





The following QTRT1 gene sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the QTRT1 gene which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu31882 NM_031209 Homo sapiens queuine tRNA-ribosyltransferase 1 (QTRT1), mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $339

*Business Day
**You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.


CloneID OHu31882
Accession Version NM_031209.2 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1212bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector Document: User manual_GenEZ ORF Clone Products.pdf (pdf)
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags Document: MSDS_GenEZ ORF Clone Products.pdf (pdf)
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product queuine tRNA-ribosyltransferase
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from CT003728.1, AF302783.1 and AF370379.1. On Jan 23, 2009 this sequence version replaced gi:13654275. Summary: This gene encodes the catalytic subunit of tRNA-guanine transglycosylase. tRNA-guanine transglycosylase is a heterodimeric enzyme complex that plays a critical role in tRNA modification by synthesizing the 7-deazaguanosine queuosine, which is found in tRNAs that code for asparagine, aspartic acid, histidine and tyrosine. A pseudogene of this gene is located on the long arm of chromosome X. [provided by RefSeq, Feb 2012]. ##Evidence-Data-START## Transcript exon combination :: AF302783.1, BC015350.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
ATGGCGGGAG CAGCTACCCA GGCTTCCCTG GAGTCGGCCC CACGGATCAT GCGGCTGGTG 
GCCGAATGCA GCCGCTCCAG GGCCCGGGCA GGCGAGCTGT GGCTGCCGCA TGGGACAGTG
GCCACTCCTG TGTTCATGCC AGTGGGCACG CAGGCCACCA TGAAGGGCAT CACGACCGAA
CAGCTGGACG CTCTGGGTTG CCGCATCTGC CTGGGCAATA CCTACCATCT GGGTCTAAGG
CCGGGACCCG AGCTGATCCA GAAAGCCAAC GGTCTCCACG GCTTCATGAA TTGGCCTCAT
AATCTGCTAA CGGACAGCGG CGGTTTCCAG ATGGTGTCGC TGGTGTCTCT GTCCGAGGTG
ACGGAGGAGG GCGTCCGCTT CCGCTCCCCC TACGACGGCA ATGAGACCCT GCTGAGCCCG
GAGAAATCCG TGCAGATCCA GAATGCGCTG GGCTCGGACA TCATCATGCA GCTGGACGAC
GTGGTTAGCA GTACTGTGAC TGGGCCACGT GTGGAGGAGG CCATGTACAG GTCAATCCGC
TGGCTGGACC GGTGCATTGC AGCCCATCAG CGGCCGGACA AGCAGAACCT CTTCGCCATT
ATCCAGGGTG GGCTGGACGC AGATCTCCGG GCCACCTGCC TTGAAGAGAT GACCAAGCGA
GACGTGCCTG GCTTCGCCAT CGGGGGCCTG AGCGGGGGTG AGAGCAAGTC GCAGTTCTGG
CGGATGGTGG CGCTGAGCAC CTCTCGGCTG CCGAAGGACA AGCCCCGATA TCTGATGGGG
GTTGGCTATG CCACTGATCT GGTAGTCTGC GTGGCTCTTG GATGTGACAT GTTCGACTGC
GTCTTCCCCA CACGGACAGC GCGCTTTGGC TCTGCCCTGG TGCCCACTGG GAACCTGCAG
TTGAGGAAGA AGGTGTTTGA GAAGGACTTC GGCCCCATAG ACCCGGAGTG CACCTGCCCC
ACGTGCCAAA AGCACAGCCG CGCCTTCCTG CACGCACTGC TGCACAGTGA CAACACGGCC
GCGCTGCACC ACCTCACGGT CCACAACATC GCCTACCAGC TGCAGCTCAT GAGCGCCGTC
CGCACCAGCA TCGTGGAGAA GCGCTTCCCG GACTTCGTGC GGGACTTCAT GGGCGCCATG
TACGGGGATC CCACCCTCTG TCCCACCTGG GCCACTGACG CTCTGGCCTC TGTGGGAATC
ACACTGGGCT GA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_112486.1
CDS26..1237
Misc Feature(1)29..31(+)
Misc Feature(2)92..1177(+)
Misc Feature(3)101..1153(+)
Exon (1)1..268
Gene:QTRT1
Gene Synonym:
Exon (2)269..337
Gene:QTRT1
Gene Synonym:
Exon (3)338..476
Gene:QTRT1
Gene Synonym:
Exon (4)477..555
Gene:QTRT1
Gene Synonym:
Exon (5)556..671
Gene:QTRT1
Gene Synonym:
Exon (6)672..810
Gene:QTRT1
Gene Synonym:
Exon (7)811..886
Gene:QTRT1
Gene Synonym:
Exon (8)887..996
Gene:QTRT1
Gene Synonym:
Exon (9)997..1084
Gene:QTRT1
Gene Synonym:
Exon (10)1085..1334
Gene:QTRT1
Gene Synonym:
Translation
Position Chain Variation Link
1 1 c, g dbSNP:376411821
3 3 a, c, t dbSNP:763589287
6 6 a, g dbSNP:774312277
8 8 c, g dbSNP:759593951
9 9 c, t dbSNP:572974407
14 14 c, t dbSNP:753023258
16 16 c, g dbSNP:760866345
20 20 c, g dbSNP:763914076
22 22 c, t dbSNP:753589190
29 29 a, g dbSNP:757208088
31 31 c, g dbSNP:778848001
33 33 a, g dbSNP:149290202
34 34 a, g dbSNP:757990412
35 35 c, g dbSNP:181204668
43 43 a, c dbSNP:746701882
44 44 c, g dbSNP:146247634
46 46 c, g dbSNP:778308677
48 48 a, c, t dbSNP:749616579
53 53 c, t dbSNP:774991140
61 61 a, g dbSNP:759948095
63 63 a, c dbSNP:562242833
64 64 c, t dbSNP:775514597
69 69 a, g dbSNP:760917157
70 70 c, g dbSNP:764251539
77 77 c, g dbSNP:753647240
78 78 a, g dbSNP:761526318
81 81 c, t dbSNP:764933359
82 82 a, g dbSNP:142070672
88 88 c, t dbSNP:758243489
89 89 g, t dbSNP:779647818
95 95 a, g dbSNP:751068312
97 97 c, t dbSNP:754694545
98 98 c, g dbSNP:780929279
106 106 a, g dbSNP:747798898
107 107 a, g dbSNP:184297648
113 113 g, t dbSNP:779127132
121 121 c, g dbSNP:746428669
127 127 c, g dbSNP:772417709
133 133 g, t dbSNP:775567862
135 135 a, g dbSNP:747033386
137 137 a, g dbSNP:768866837
141 141 a, c dbSNP:776902309
142 142 a, g dbSNP:761924157
152 152 a, c dbSNP:11542288
162 162 c, t dbSNP:765126478
187 187 c, g dbSNP:772844765
193 193 c, g dbSNP:762973896
215 215 g, t dbSNP:766364649
222 222 a, g dbSNP:751123438
227 227 c, t dbSNP:754602465
234 234 a, g dbSNP:767123036
246 246 c, t dbSNP:775368753
247 247 c, g dbSNP:752448084
250 250 c, t dbSNP:755694204
253 253 c, t dbSNP:551209802
264 264 a, g dbSNP:779364075
269 269 g, t dbSNP:750800993
274 274 a, c, g dbSNP:11542289
283 283 c, g dbSNP:780382956
294 294 a, g dbSNP:752108321
296 296 c, g dbSNP:369761816
297 297 a, g dbSNP:781274508
305 305 a, g dbSNP:748119986
309 309 g, t dbSNP:770060335
316 316 c, t dbSNP:756838636
337 337 -, g dbSNP:764802002
346 346 -, g dbSNP:367710179
349 349 g, t dbSNP:745598919
361 361 a, g dbSNP:375649062
374 374 a, c, g dbSNP:139560362
383 383 a, g dbSNP:760643976
397 397 c, t dbSNP:768099498
398 398 a, g dbSNP:776175145
407 407 c, t dbSNP:761483374
411 411 c, t dbSNP:549095358
416 416 c, t dbSNP:751927754
421 421 c, t dbSNP:750154565
426 426 a, g dbSNP:759960986
427 427 c, g, t dbSNP:767910965
429 429 -, cat dbSNP:572327869
433 433 c, g dbSNP:756616780
439 439 a, g dbSNP:764114075
440 440 a, g dbSNP:753922797
441 441 c, g dbSNP:567445299
443 443 a, c dbSNP:779206294
445 445 a, g dbSNP:746079568
453 453 a, c, g dbSNP:758181742
456 456 a, t dbSNP:376848453
463 463 a, c, t dbSNP:746958993
471 471 a, c dbSNP:776026372
473 473 c, t dbSNP:370957210
474 474 c, t dbSNP:769290351
475 475 g, t dbSNP:772908833
481 481 a, g dbSNP:142809082
495 495 a, g dbSNP:762384233
502 502 c, t dbSNP:151104617
503 503 a, g dbSNP:750489493
505 505 c, t dbSNP:763105761
506 506 a, g dbSNP:140013394
525 525 a, c dbSNP:751728487
531 531 c, t dbSNP:754862370
534 534 a, g dbSNP:371833469
541 541 a, g dbSNP:752672370
546 546 c, t dbSNP:756008812
560 560 a, g dbSNP:766358041
563 563 c, g, t dbSNP:751857027
564 564 a, g, t dbSNP:767335139
575 575 c, t dbSNP:756061844
576 576 a, g dbSNP:777623622
582 582 c, t dbSNP:375494589
586 586 a, g dbSNP:756846896
589 589 c, t dbSNP:778260603
597 597 a, g dbSNP:745571805
598 598 a, g dbSNP:369934212
599 599 c, t dbSNP:149820141
600 600 c, t dbSNP:748463873
601 601 a, g dbSNP:147936975
605 605 a, g dbSNP:188490696
609 609 a, c dbSNP:763349489
612 612 a, g dbSNP:771082404
614 614 c, t dbSNP:774256789
619 619 c, t dbSNP:759779117
626 626 a, g dbSNP:767672430
633 633 a, g dbSNP:775271217
643 643 c, t dbSNP:760533220
644 644 a, g dbSNP:763860657
650 650 a, c dbSNP:753860412
653 653 c, t dbSNP:200856404
660 660 c, t dbSNP:764831399
661 661 c, g dbSNP:749852651
676 676 a, g dbSNP:373758980
678 678 c, g dbSNP:767015466
684 684 a, g dbSNP:752392015
688 688 c, t dbSNP:757623844
689 689 a, g dbSNP:779310852
692 692 c, t dbSNP:750966175
697 697 a, c dbSNP:372190047
700 700 c, t dbSNP:780126367
701 701 a, g dbSNP:747033265
703 703 c, t dbSNP:768926905
706 706 c, t dbSNP:141223779
707 707 a, c, g, t dbSNP:748388439
709 709 a, g dbSNP:763009237
715 715 a, g dbSNP:770935667
719 719 a, c, g dbSNP:774006414
725 725 a, g dbSNP:767045564
730 730 c, g dbSNP:752344491
736 736 a, g dbSNP:760339670
737 737 a, c dbSNP:765616657
742 742 c, g dbSNP:750735108
747 747 a, g dbSNP:758077445
756 756 c, t dbSNP:780470865
757 757 a, g dbSNP:752055092
758 758 c, t dbSNP:755070909
770 770 c, t dbSNP:374828333
771 771 a, g dbSNP:778314906
773 773 a, c dbSNP:770011192
777 777 c, t dbSNP:369146285
778 778 a, g dbSNP:146967568
783 783 a, c, g dbSNP:550711660
792 792 a, g dbSNP:774493372
797 797 c, g dbSNP:562635504
803 803 g, t dbSNP:375467277
807 807 c, t dbSNP:372877738
836 836 a, g dbSNP:147590804
838 838 a, g dbSNP:756322137
839 839 a, g, t dbSNP:764251932
842 842 c, t dbSNP:757510609
844 844 c, t dbSNP:778591627
854 854 a, g dbSNP:745616769
859 859 c, t dbSNP:758269870
865 865 c, t dbSNP:568267343
866 866 a, g dbSNP:746933825
876 876 c, t dbSNP:768204014
878 878 c, t dbSNP:780648676
879 879 a, g dbSNP:548731555
880 880 g, t dbSNP:769379843
885 885 c, t dbSNP:774585166
886 886 a, g dbSNP:760014409
887 887 c, t dbSNP:776852465
889 889 c, t dbSNP:762047406
911 911 a, g dbSNP:568561273
916 916 a, g dbSNP:765216154
919 919 a, c dbSNP:750704961
922 922 a, c, g dbSNP:558366017
923 923 c, t dbSNP:751297818
926 926 c, t dbSNP:149020533
938 938 g, t dbSNP:767510956
955 955 c, t dbSNP:752619320
964 964 a, g dbSNP:755701974
969 969 c, t dbSNP:777119621
970 970 a, g dbSNP:749004153
977 977 a, c dbSNP:756815079
979 979 a, c dbSNP:780575417
983 983 c, t dbSNP:377022672
984 984 c, t dbSNP:769134436
987 987 a, c, t dbSNP:777332800
988 988 a, g dbSNP:200166101
992 992 c, g dbSNP:773124289
1003 1003 c, g dbSNP:749396301
1004 1004 c, t dbSNP:148263925
1005 1005 a, g dbSNP:562572604
1006 1006 c, t dbSNP:759725869
1007 1007 a, g dbSNP:767334871
1009 1009 c, t dbSNP:775102221
1015 1015 a, g dbSNP:760678804
1016 1016 c, t dbSNP:763866468
1018 1018 c, t dbSNP:367752785
1019 1019 a, g dbSNP:761284281
1020 1020 a, c dbSNP:533239108
1024 1024 a, g dbSNP:769867462
1041 1041 c, t dbSNP:371698625
1042 1042 a, g dbSNP:202055397
1045 1045 c, t dbSNP:141380341
1046 1046 a, g dbSNP:756496433
1047 1047 c, t dbSNP:778203279
1060 1060 c, t dbSNP:749781310
1062 1062 a, c, t dbSNP:771040481
1063 1063 a, g dbSNP:201592010
1071 1071 a, g dbSNP:370265794
1073 1073 a, g dbSNP:145429723
1075 1075 c, t dbSNP:568334935
1076 1076 g, t dbSNP:768481230
1096 1096 -, g dbSNP:773888579
1098 1098 a, c, g dbSNP:772853270
1099 1099 a, c, t dbSNP:138077932
1100 1100 a, g dbSNP:759190680
1102 1102 c, t dbSNP:574255566
1103 1103 a, g dbSNP:754147172
1105 1105 c, t dbSNP:757770049
1106 1106 c, t dbSNP:377094295
1107 1107 a, g dbSNP:368812526
1109 1109 a, g, t dbSNP:562860104
1115 1115 a, g dbSNP:370588978
1117 1117 c, t dbSNP:764257788
1118 1118 a, g dbSNP:780862075
1129 1129 c, g dbSNP:747885034
1135 1135 a, g dbSNP:553198610
1138 1138 c, t dbSNP:773330704
1140 1140 g, t dbSNP:749206113
1141 1141 c, t dbSNP:139740339
1142 1142 a, g dbSNP:560594127
1146 1146 a, g dbSNP:146321060
1152 1152 c, t dbSNP:767127490
1159 1159 a, c dbSNP:775115458
1160 1160 a, g dbSNP:372871774
1164 1164 c, t dbSNP:200907243
1168 1168 c, t dbSNP:188263528
1169 1169 a, g dbSNP:758901321
1172 1172 a, g dbSNP:766394532
1173 1173 -, atccca dbSNP:769442907
1177 1177 c, t dbSNP:751601303
1178 1178 -, gg dbSNP:774797596
1179 1179 c, t dbSNP:148155872
1191 1191 c, g, t dbSNP:755160955
1192 1192 c, g dbSNP:748357640
1204 1204 c, t dbSNP:375875231
1205 1205 a, g dbSNP:774402365
1213 1213 c, t dbSNP:181143144
1231 1231 g, t dbSNP:11672431
1243 1243 c, g dbSNP:766071800
1245 1245 c, t dbSNP:770841091
1251 1251 -, agggagggaggaagga dbSNP:762736776
1251 1251 c, g dbSNP:773735654
1253 1253 a, c, g dbSNP:550857832
1265 1265 c, g dbSNP:775176617
1267 1267 -, aggg dbSNP:763645061

Target ORF information:

RefSeq Version NM_031209
Organism Homo sapiens (human)
Definition Homo sapiens queuine tRNA-ribosyltransferase 1 (QTRT1), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_031209

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
ATGGCGGGAG CAGCTACCCA GGCTTCCCTG GAGTCGGCCC CACGGATCAT GCGGCTGGTG 
GCCGAATGCA GCCGCTCCAG GGCCCGGGCA GGCGAGCTGT GGCTGCCGCA TGGGACAGTG
GCCACTCCTG TGTTCATGCC AGTGGGCACG CAGGCCACCA TGAAGGGCAT CACGACCGAA
CAGCTGGACG CTCTGGGTTG CCGCATCTGC CTGGGCAATA CCTACCATCT GGGTCTAAGG
CCGGGACCCG AGCTGATCCA GAAAGCCAAC GGTCTCCACG GCTTCATGAA TTGGCCTCAT
AATCTGCTAA CGGACAGCGG CGGTTTCCAG ATGGTGTCGC TGGTGTCTCT GTCCGAGGTG
ACGGAGGAGG GCGTCCGCTT CCGCTCCCCC TACGACGGCA ATGAGACCCT GCTGAGCCCG
GAGAAATCCG TGCAGATCCA GAATGCGCTG GGCTCGGACA TCATCATGCA GCTGGACGAC
GTGGTTAGCA GTACTGTGAC TGGGCCACGT GTGGAGGAGG CCATGTACAG GTCAATCCGC
TGGCTGGACC GGTGCATTGC AGCCCATCAG CGGCCGGACA AGCAGAACCT CTTCGCCATT
ATCCAGGGTG GGCTGGACGC AGATCTCCGG GCCACCTGCC TTGAAGAGAT GACCAAGCGA
GACGTGCCTG GCTTCGCCAT CGGGGGCCTG AGCGGGGGTG AGAGCAAGTC GCAGTTCTGG
CGGATGGTGG CGCTGAGCAC CTCTCGGCTG CCGAAGGACA AGCCCCGATA TCTGATGGGG
GTTGGCTATG CCACTGATCT GGTAGTCTGC GTGGCTCTTG GATGTGACAT GTTCGACTGC
GTCTTCCCCA CACGGACAGC GCGCTTTGGC TCTGCCCTGG TGCCCACTGG GAACCTGCAG
TTGAGGAAGA AGGTGTTTGA GAAGGACTTC GGCCCCATAG ACCCGGAGTG CACCTGCCCC
ACGTGCCAAA AGCACAGCCG CGCCTTCCTG CACGCACTGC TGCACAGTGA CAACACGGCC
GCGCTGCACC ACCTCACGGT CCACAACATC GCCTACCAGC TGCAGCTCAT GAGCGCCGTC
CGCACCAGCA TCGTGGAGAA GCGCTTCCCG GACTTCGTGC GGGACTTCAT GGGCGCCATG
TACGGGGATC CCACCCTCTG TCCCACCTGG GCCACTGACG CTCTGGCCTC TGTGGGAATC
ACACTGGGCT GA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.