||ORF Nucleotide Sequence (Length: 312bp)
||pcDNA3.1-C-(k)DYK or customized vector
|Tag on pcDNA3.1-C-(k)DYK
||C terminal DYKDDDDK tags
|ORF Insert Method
||CloneEZ® Seamless cloning technology
||Homo sapiens (human)
||REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from AB000905.1.
On Jan 10, 2002 this sequence version replaced gi:4504320.
Summary: Histones are basic nuclear proteins that are responsible
for the nucleosome structure of the chromosomal fiber in
eukaryotes. Two molecules of each of the four core histones (H2A,
H2B, H3, and H4) form an octamer, around which approximately 146 bp
of DNA is wrapped in repeating units, called nucleosomes. The
linker histone, H1, interacts with linker DNA between nucleosomes
and functions in the compaction of chromatin into higher order
structures. This gene is intronless and encodes a
replication-dependent histone that is a member of the histone H4
family. Transcripts from this gene lack polyA tails but instead
contain a palindromic termination element. This gene is found in
the histone microcluster on chromosome 6p21.33. [provided by
RefSeq, Aug 2015].
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
replication-dependent histone :: PMID: 12408966
COMPLETENESS: complete on the 3' end.