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HIST1H2AL histone cluster 1, H2al [Homo sapiens (human)]

Gene Symbol HIST1H2AL
Entrez Gene ID 8332
Full Name histone cluster 1, H2al
Synonyms H2A.i, H2A/i, H2AFI, dJ193B12.9
General protein information
Preferred Names
histone H2A type 1
Names
histone H2A type 1
H2A.1
histone 1, H2al
H2A histone family, member I
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

6

6p22.1

Summary Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2A family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the small histone gene cluster on chromosome 6p22-p21.3. [provided by RefSeq, Aug 2015]. lac of sum
Disorder MIM:

602793

Disorder Html:





The following HIST1H2AL gene sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the HIST1H2AL gene which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu13075 NM_003511 Homo sapiens histone cluster 1, H2al (HIST1H2AL), mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$69.3
$99

*Business Day
**You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.


CloneID OHu13075
Accession Version NM_003511.2 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 393bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 18-AUG-2015
Organism Homo sapiens (human)
Product histone H2A type 1
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from X83549.1. On Sep 21, 2001 this sequence version replaced gi:4504242. Summary: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2A family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the small histone gene cluster on chromosome 6p22-p21.3. [provided by RefSeq, Aug 2015]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript is intronless :: BC069306.1 [ECO:0000345] ##Evidence-Data-END## ##RefSeq-Attributes-START## replication-dependent histone :: PMID: 12408966 ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
ATGTCGGGAC GCGGCAAGCA GGGAGGCAAA GCTCGCGCCA AAGCCAAGAC CCGCTCTTCT 
CGTGCCGGTC TCCAGTTCCC CGTGGGCCGA GTGCACCGAC TGCTCCGCAA GGGCAACTAT
GCTGAGCGGG TCGGGGCCGG CGCGCCGGTG TACCTGGCGG CGGTGCTGGA GTACCTGACT
GCCGAGATCC TGGAGCTGGC GGGCAACGCC GCCCGCGACA ACAAGAAGAC CCGCATTATC
CCGCGCCACT TGCAGCTGGC CATCCGCAAC GACGAGGAGC TCAACAAGCT GCTGGGCAAA
GTAACCATCG CTCAGGGTGG TGTCCTGCCC AACATCCAGG CTGTGCTACT GCCCAAGAAG
ACCGAGAGTC ACCACAAGGC CAAAGGCAAA TAA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_003502.1
CDS27..419
Misc Feature(1)27..416(+)
Misc Feature(2)30..32(+)
Misc Feature(3)30..32(+)
Misc Feature(4)36..38(+)
Misc Feature(5)36..38(+)
Misc Feature(6)42..386(+)
Misc Feature(7)42..56(+)
Misc Feature(8)42..44(+)
Misc Feature(9)114..260(+)
Misc Feature(10)135..137(+)
Misc Feature(11)141..152(+)
Misc Feature(12)180..218(+)
Misc Feature(13)339..341(+)
Misc Feature(14)381..383(+)
Misc Feature(15)384..386(+)
Misc Feature(16)384..386(+)
Misc Feature(17)387..389(+)
Misc Feature(18)393..395(+)
Misc Feature(19)402..404(+)
Exon (1)1..470
Gene:HIST1H2AL
Gene Synonym:
Translation
Position Chain Variation Link
2 2 g, t dbSNP:771377224
4 4 c, t dbSNP:775336124
5 5 c, g, t dbSNP:201897403
7 7 c, t dbSNP:193158953
8 8 c, t dbSNP:761330719
10 10 c, t dbSNP:375100048
13 13 a, g, t dbSNP:773094384
15 15 -, gttt dbSNP:756474190
15 15 c, t dbSNP:766140113
20 20 a, c dbSNP:554933127
24 24 a, g dbSNP:755148592
26 26 c, t dbSNP:765412284
27 27 a, c dbSNP:752728797
28 28 a, c, t dbSNP:758432501
29 29 a, g, t dbSNP:747499234
31 31 c, t dbSNP:201871635
32 32 c, g, t dbSNP:58854344
35 35 a, g dbSNP:773987773
36 36 c, t dbSNP:748822589
39 39 c, g dbSNP:747643569
44 44 a, c, g dbSNP:771562270
48 48 a, g dbSNP:760573810
51 51 g, t dbSNP:766226775
53 53 c, t dbSNP:200926105
57 57 g, t dbSNP:759314041
58 58 a, c dbSNP:765379220
62 62 a, c dbSNP:752919454
68 68 a, g dbSNP:200981
69 69 g, t dbSNP:764241965
71 71 a, c dbSNP:752182301
72 72 -, t dbSNP:780542650
72 72 a, t dbSNP:371961381
74 74 g, t dbSNP:781742626
76 76 c, t dbSNP:150544468
77 77 c, t dbSNP:756461663
80 80 c, t dbSNP:778452920
85 85 -, c dbSNP:754451360
85 85 c, t dbSNP:184589037
87 87 c, g, t dbSNP:771521342
88 88 g, t dbSNP:747004657
89 89 a, c, t dbSNP:112071135
91 91 c, t dbSNP:776480510
92 92 a, c, g dbSNP:770768543
93 93 -, g dbSNP:755534499
94 94 g, t dbSNP:769613461
104 104 c, t dbSNP:775619752
109 109 -, a dbSNP:779493045
113 113 c, t dbSNP:763235615
122 122 c, t dbSNP:533619733
123 123 c, t dbSNP:764330058
125 125 a, c dbSNP:751704432
131 131 -, c dbSNP:746511146
131 131 c, t dbSNP:761920237
132 132 c, t dbSNP:576189710
133 133 g, t dbSNP:750894974
137 137 a, g dbSNP:756484311
140 140 c, t dbSNP:780435458
142 142 a, c, g, t dbSNP:752356760
144 144 c, t dbSNP:375263252
149 149 g, t dbSNP:770384072
151 151 a, g dbSNP:781011185
156 156 g, t dbSNP:745790671
157 157 c, t dbSNP:139452482
158 158 a, c, t dbSNP:775345207
161 161 a, g dbSNP:769005541
162 162 -, gccggcgc dbSNP:770430209
162 162 g, t dbSNP:774677441
164 164 c, t dbSNP:561805457
168 168 a, g dbSNP:767683230
170 170 c, g dbSNP:773631542
172 172 c, g dbSNP:761239027
173 173 g, t dbSNP:766710032
174 174 a, g, t dbSNP:754241683
175 175 g, t dbSNP:763762817
179 179 c, t dbSNP:145617698
185 185 a, g, t dbSNP:756803514
185 185 -, g dbSNP:780743516
187 187 a, c, t dbSNP:141399242
197 197 a, g dbSNP:779790992
200 200 c, t dbSNP:749128960
206 206 a, c, t dbSNP:369581178
207 207 c, g dbSNP:368720914
209 209 c, g, t dbSNP:41269275
214 214 a, t dbSNP:760612287
215 215 c, t dbSNP:766910834
216 216 c, g dbSNP:776962048
218 218 a, g dbSNP:371689505
221 221 c, g dbSNP:765561212
222 222 c, t dbSNP:775586680
224 224 a, g dbSNP:751283542
229 229 c, g dbSNP:756893472
232 232 a, g dbSNP:766826911
236 236 c, t dbSNP:11966705
240 240 c, t dbSNP:749956603
245 245 c, t dbSNP:755541479
248 248 c, g dbSNP:149390187
251 251 a, g dbSNP:376667817
254 254 a, g dbSNP:369844593
257 257 c, t dbSNP:754861911
260 260 c, t dbSNP:778846277
263 263 c, t dbSNP:748439220
269 269 g, t dbSNP:772351305
272 272 c, t dbSNP:773240444
274 274 a, c, g dbSNP:190008233
299 299 c, t dbSNP:373542627
305 305 a, g dbSNP:760036226
306 306 c, g dbSNP:770206237
315 315 c, t dbSNP:200871977
329 329 a, c dbSNP:142186318
333 333 a, g dbSNP:763239054
337 337 c, t dbSNP:767231732
358 358 a, g dbSNP:144728921
359 359 a, c dbSNP:777338790
362 362 a, c dbSNP:762266017
365 365 g, t dbSNP:760282072
371 371 g, t dbSNP:138346783
376 376 -, ta dbSNP:769628494
380 380 c, t dbSNP:753892286
387 387 -, c dbSNP:775252690
388 388 c, g dbSNP:375805669
390 390 a, g dbSNP:778934233
396 396 c, t dbSNP:752544024
405 405 a, g dbSNP:758085860
407 407 c, t dbSNP:778075472
416 416 a, g dbSNP:199657823
423 423 c, t dbSNP:747173354
425 425 a, c, t dbSNP:375707461
428 428 c, t dbSNP:781239752
432 432 a, g dbSNP:745894126
434 434 c, g dbSNP:770292287
439 439 c, t dbSNP:551738544
449 449 a, c, t dbSNP:201760429
450 450 a, g dbSNP:772958913
452 452 c, t dbSNP:760242138
463 463 a, g dbSNP:766042861
468 468 -, cta dbSNP:768586828
468 468 c, g dbSNP:113256110

Target ORF information:

RefSeq Version NM_003511
Organism Homo sapiens (human)
Definition Homo sapiens histone cluster 1, H2al (HIST1H2AL), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_003511

ORF Insert Sequence:

1
61
121
181
241
301
361
ATGTCGGGAC GCGGCAAGCA GGGAGGCAAA GCTCGCGCCA AAGCCAAGAC CCGCTCTTCT 
CGTGCCGGTC TCCAGTTCCC CGTGGGCCGA GTGCACCGAC TGCTCCGCAA GGGCAACTAT
GCTGAGCGGG TCGGGGCCGG CGCGCCGGTG TACCTGGCGG CGGTGCTGGA GTACCTGACT
GCCGAGATCC TGGAGCTGGC GGGCAACGCC GCCCGCGACA ACAAGAAGAC CCGCATTATC
CCGCGCCACT TGCAGCTGGC CATCCGCAAC GACGAGGAGC TCAACAAGCT GCTGGGCAAA
GTAACCATCG CTCAGGGTGG TGTCCTGCCC AACATCCAGG CTGTGCTACT GCCCAAGAAG
ACCGAGAGTC ACCACAAGGC CAAAGGCAAA TAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.