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HIST1H2BG histone cluster 1, H2bg [Homo sapiens (human)]

Gene Symbol HIST1H2BG
Entrez Gene ID 8339
Full Name histone cluster 1, H2bg
Synonyms H2B.1A, H2B/a, H2BFA, dJ221C16.8
General protein information
Preferred Names
histone H2B type 1-C/E/F/G/I
Names
histone H2B type 1-C/E/F/G/I
histone H2B.a
histone 1, H2bg
histone H2B.1 A
H2B histone family, member A
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

6

6p22.2

Summary Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. The protein has antibacterial and antifungal antimicrobial activity. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2B family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3. [provided by RefSeq, Aug 2015]. lac of sum
Disorder MIM:

602798

Disorder Html:





The following HIST1H2BG gene sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the HIST1H2BG gene which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu30077 NM_003518 Homo sapiens histone cluster 1, H2bg (HIST1H2BG), mRNA. pcDNA3.1+/C-(K)DYK or customized vector 5-7 $99

*Business Day
**You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.


CloneID OHu30077
Accession Version NM_003518.3 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 381bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector Document: User manual_GenEZ ORF Clone Products.pdf (pdf)
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags Document: MSDS_GenEZ ORF Clone Products.pdf (pdf)
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 18-AUG-2015
Organism Homo sapiens (human)
Product histone H2B type 1-C/E/F/G/I
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from M60750.1. On Jun 21, 2002 this sequence version replaced gi:19923172. Summary: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. The protein has antibacterial and antifungal antimicrobial activity. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2B family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3. [provided by RefSeq, Aug 2015]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##RefSeq-Attributes-START## Protein has antimicrobial activity :: PMID: 12860195 replication-dependent histone :: PMID: 12408966 ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
ATGCCTGAAC CAGCTAAGTC AGCTCCTGCT CCGAAGAAGG GTTCCAAGAA GGCTGTGACC 
AAGGCGCAGA AGAAGGATGG CAAGAAGCGC AAGCGCAGTC GTAAGGAGAG CTACTCCGTG
TATGTGTACA AGGTGCTAAA ACAGGTTCAC CCCGATACTG GCATCTCATC CAAGGCCATG
GGCATCATGA ATTCCTTCGT TAACGACATC TTCGAACGCA TCGCAGGCGA GGCTTCCCGT
CTGGCCCACT ACAACAAGCG CTCGACCATT ACCTCCAGGG AGATCCAGAC CGCCGTGCGT
CTGCTGCTTC CCGGAGAGCT GGCCAAGCAC GCAGTGTCCG AAGGTACCAA GGCTGTCACC
AAGTATACAA GCTCCAAGTA A
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_003509.1
CDS2..382
Misc Feature(1)5..7(+)
Misc Feature(2)17..19(+)
Misc Feature(3)17..19(+)
Misc Feature(4)35..37(+)
Misc Feature(5)35..37(+)
Misc Feature(6)38..40(+)
Misc Feature(7)38..40(+)
Misc Feature(8)44..46(+)
Misc Feature(9)47..49(+)
Misc Feature(10)47..49(+)
Misc Feature(11)50..52(+)
Misc Feature(12)50..52(+)
Misc Feature(13)62..64(+)
Misc Feature(14)62..64(+)
Misc Feature(15)71..73(+)
Misc Feature(16)71..73(+)
Misc Feature(17)83..373(+)
Misc Feature(18)104..106(+)
Misc Feature(19)110..112(+)
Misc Feature(20)140..142(+)
Misc Feature(21)173..175(+)
Misc Feature(22)239..241(+)
Misc Feature(23)257..259(+)
Misc Feature(24)257..259(+)
Misc Feature(25)260..262(+)
Misc Feature(26)278..280(+)
Misc Feature(27)326..328(+)
Misc Feature(28)347..349(+)
Misc Feature(29)350..352(+)
Exon (1)1..445
Gene:HIST1H2BG
Gene Synonym:
Translation
Position Chain Variation Link
1 1 c, t dbSNP:776934484
4 4 a, g, t dbSNP:148814957
6 6 c, g dbSNP:773203416
7 7 c, t dbSNP:771976174
10 10 a, g dbSNP:372673859
11 11 a, c, g dbSNP:191008734
12 12 c, t dbSNP:202162061
14 14 a, c, g dbSNP:769401291
15 15 c, g, t dbSNP:778162085
16 16 c, t dbSNP:758732493
21 21 a, c, g, t dbSNP:145524593
24 24 c, t dbSNP:753793487
25 25 g, t dbSNP:368880863
26 26 c, t dbSNP:149681157
27 27 c, t dbSNP:575981224
29 29 c, g, t dbSNP:761654812
30 30 c, t dbSNP:114698706
32 32 c, g, t dbSNP:146860350
35 35 a, c dbSNP:774920524
37 37 -, c dbSNP:765204307
37 37 a, g dbSNP:769327331
40 40 c, g dbSNP:745560922
41 41 a, g dbSNP:780781537
46 46 c, t dbSNP:143774290
55 55 c, t dbSNP:748454377
58 58 g, t dbSNP:779477632
60 60 c, g dbSNP:755499900
61 61 c, g, t dbSNP:144645222
63 63 a, g dbSNP:756229739
65 65 a, c, g, t dbSNP:146142074
66 66 a, c, t dbSNP:142815649
69 69 a, g dbSNP:763936797
74 74 -, aag dbSNP:763480943
76 76 a, g dbSNP:762848033
81 81 -, g dbSNP:753597313
85 85 a, g dbSNP:775468179
88 88 g, t dbSNP:769326895
92 92 a, c dbSNP:758995956
94 94 a, g dbSNP:533938487
103 103 c, t dbSNP:770502877
106 106 a, g dbSNP:751156445
112 112 c, t dbSNP:117226020
115 115 c, t dbSNP:769039154
119 119 g, t dbSNP:749796846
120 120 c, t dbSNP:780568228
121 121 c, g dbSNP:756278826
124 124 c, t dbSNP:745879206
125 125 g, t dbSNP:781421534
127 127 a, c, g, t dbSNP:555818951
129 129 a, g dbSNP:758174332
132 132 a, g dbSNP:752597600
136 136 a, g dbSNP:765100725
140 140 a, t dbSNP:759051084
143 143 c, t dbSNP:376254420
151 151 c, t dbSNP:765857790
155 155 a, g dbSNP:760291254
163 163 c, t dbSNP:772886682
166 166 a, c, g dbSNP:749610657
172 172 c, t dbSNP:140919872
175 175 a, g dbSNP:372917727
176 176 a, g dbSNP:746368662
177 177 c, t dbSNP:781470850
178 178 c, t dbSNP:762435555
179 179 a, g dbSNP:200965546
190 190 g, t dbSNP:747228517
191 191 -, t dbSNP:766192153
196 196 a, c dbSNP:778005479
199 199 c, t dbSNP:570046076
208 208 c, t dbSNP:752469309
211 211 a, c, t dbSNP:374281578
217 217 a, g, t dbSNP:41266811
218 218 c, t dbSNP:765911190
219 219 c, g dbSNP:760189973
221 221 a, t dbSNP:772758945
223 223 c, t dbSNP:767133701
229 229 c, t dbSNP:761370253
233 233 a, g dbSNP:776059675
234 234 c, g dbSNP:770265113
239 239 a, c, t dbSNP:777238838
240 240 g, t dbSNP:779443828
241 241 c, t dbSNP:770940533
242 242 c, t dbSNP:747050536
244 244 g, t dbSNP:777861065
247 247 c, g dbSNP:772404532
248 248 c, t dbSNP:748304068
250 250 c, t dbSNP:778724341
253 253 a, c, g, t dbSNP:369376110
255 255 a, g dbSNP:755586518
256 256 c, t dbSNP:750019670
259 259 a, g dbSNP:202170052
261 261 a, g dbSNP:761580046
262 262 c, g dbSNP:751225846
265 265 a, g dbSNP:765729377
267 267 c, t dbSNP:759933007
269 269 a, g dbSNP:375561975
277 277 a, c, t dbSNP:201957387
280 280 a, g dbSNP:139135890
285 285 g, t dbSNP:772022131
286 286 c, g dbSNP:748405525
288 288 a, c dbSNP:779063580
289 289 a, g, t dbSNP:16891427
292 292 c, t dbSNP:372346685
295 295 a, c, t dbSNP:756138373
296 296 a, g, t dbSNP:368649575
298 298 a, g dbSNP:143613920
302 302 c, t dbSNP:377201962
313 313 c, g dbSNP:371778293
331 331 c, t dbSNP:751280874
332 332 a, g dbSNP:367765460
337 337 a, g dbSNP:763783564
340 340 c, t dbSNP:186981469
352 352 a, g dbSNP:138214841
353 353 c, g dbSNP:754320179
355 355 -, t dbSNP:760271385
358 358 c, t dbSNP:766638514
361 361 c, g, t dbSNP:773561876
364 364 a, g dbSNP:767666925
367 367 c, t dbSNP:761831024
372 372 a, g dbSNP:774567730
374 374 a, t dbSNP:768934674
376 376 c, t dbSNP:182318715
381 381 a, g dbSNP:775404879
384 384 c, t dbSNP:199951228
385 385 g, t dbSNP:745853955
387 387 a, g dbSNP:780946079
388 388 a, t dbSNP:772220232
389 389 g, t dbSNP:746456357
391 391 c, t dbSNP:777415026
392 392 c, t dbSNP:548265162
396 396 c, t dbSNP:752372359
398 398 c, g, t dbSNP:374205944
401 401 c, t dbSNP:750962368
406 406 c, g dbSNP:767852202
407 407 c, t dbSNP:200940163
408 408 -, t dbSNP:771418876
408 408 c, g, t dbSNP:764137342
410 410 -, aa dbSNP:770067645
412 412 a, g dbSNP:370513998
416 416 c, g dbSNP:775535861
420 420 a, t dbSNP:201937698
423 423 g, t dbSNP:745595914
427 427 c, t dbSNP:776637442
428 428 a, g dbSNP:771056248
429 429 c, t dbSNP:746926779
431 431 c, t dbSNP:759761140
433 433 a, c dbSNP:777471534
436 436 c, t dbSNP:189690437
441 441 a, g dbSNP:28448296

Target ORF information:

RefSeq Version NM_003518
Organism Homo sapiens (human)
Definition Homo sapiens histone cluster 1, H2bg (HIST1H2BG), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_003518

ORF Insert Sequence:

1
61
121
181
241
301
361
ATGCCTGAAC CAGCTAAGTC AGCTCCTGCT CCGAAGAAGG GTTCCAAGAA GGCTGTGACC 
AAGGCGCAGA AGAAGGATGG CAAGAAGCGC AAGCGCAGTC GTAAGGAGAG CTACTCCGTG
TATGTGTACA AGGTGCTAAA ACAGGTTCAC CCCGATACTG GCATCTCATC CAAGGCCATG
GGCATCATGA ATTCCTTCGT TAACGACATC TTCGAACGCA TCGCAGGCGA GGCTTCCCGT
CTGGCCCACT ACAACAAGCG CTCGACCATT ACCTCCAGGG AGATCCAGAC CGCCGTGCGT
CTGCTGCTTC CCGGAGAGCT GGCCAAGCAC GCAGTGTCCG AAGGTACCAA GGCTGTCACC
AAGTATACAA GCTCCAAGTA A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.