||ORF Nucleotide Sequence (Length: 381bp)
||pcDNA3.1-C-(k)DYK or customized vector
|Tag on pcDNA3.1-C-(k)DYK
||C terminal DYKDDDDK tags
|ORF Insert Method
||CloneEZ® Seamless cloning technology
||Homo sapiens (human)
||histone H2B type 1-C/E/F/G/I
||REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from M60750.1.
On Jun 21, 2002 this sequence version replaced gi:19923172.
Summary: Histones are basic nuclear proteins that are responsible
for the nucleosome structure of the chromosomal fiber in
eukaryotes. Nucleosomes consist of approximately 146 bp of DNA
wrapped around a histone octamer composed of pairs of each of the
four core histones (H2A, H2B, H3, and H4). The chromatin fiber is
further compacted through the interaction of a linker histone, H1,
with the DNA between the nucleosomes to form higher order chromatin
structures. The protein has antibacterial and antifungal
antimicrobial activity. This gene is intronless and encodes a
replication-dependent histone that is a member of the histone H2B
family. Transcripts from this gene lack polyA tails; instead, they
contain a palindromic termination element. This gene is found in
the large histone gene cluster on chromosome 6p22-p21.3. [provided
by RefSeq, Aug 2015].
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
Protein has antimicrobial activity :: PMID: 12860195
replication-dependent histone :: PMID: 12408966
COMPLETENESS: complete on the 3' end.