The following HIST1H2BE gene sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the HIST1H2BE gene which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
||ORF Nucleotide Sequence (Length: 381bp)
||pcDNA3.1+/C-(K)DYK or customized vector
|Tag on pcDNA3.1+/C-(K)DYK
||C terminal DYKDDDDK tags
|ORF Insert Method
||CloneEZ® Seamless cloning technology
||Homo sapiens (human)
||histone H2B type 1-C/E/F/G/I
||REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from Z80780.1.
On Jun 12, 2002 this sequence version replaced gi:4504266.
Summary: Histones are basic nuclear proteins that are responsible
for the nucleosome structure of the chromosomal fiber in
eukaryotes. Two molecules of each of the four core histones (H2A,
H2B, H3, and H4) form an octamer, around which approximately 146 bp
of DNA is wrapped in repeating units, called nucleosomes. The
linker histone, H1, interacts with linker DNA between nucleosomes
and functions in the compaction of chromatin into higher order
structures. The protein has antibacterial and antifungal
antimicrobial activity. This gene is intronless and encodes a
replication-dependent histone that is a member of the histone H2B
family. Transcripts from this gene lack polyA tails but instead
contain a palindromic termination element. This gene is found in
the large histone gene cluster on chromosome 6. [provided by
RefSeq, Aug 2015].
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
Transcript is intronless :: BP362977.1 [ECO:0000345]
Protein has antimicrobial activity :: PMID: 12860195
replication-dependent histone :: PMID: 12408966
COMPLETENESS: complete on the 3' end.