||ORF Nucleotide Sequence (Length: 918bp)
||pcDNA3.1-C-(k)DYK or customized vector
|Tag on pcDNA3.1-C-(k)DYK
||C terminal DYKDDDDK tags
|ORF Insert Method
||CloneEZ® Seamless cloning technology
||Homo sapiens (human)
||N-acetylglucosamine-1-phosphotransferase subunit gamma precursor
||REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from DT219524.1, BC014592.1,
AK312067.1 and AY203933.1.
This sequence is a reference standard in the RefSeqGene project.
On Feb 12, 2010 this sequence version replaced gi:42476109.
Summary: This gene encodes the gamma sunbunit of the
N-acetylglucosamine-1-phosphotransferase complex. This hexameric
complex, composed of alpha, beta and gamma subunits, catalyzes the
first step in synthesis of a mannose 6-phosphate lysosomal
recognition marker. This enzyme complex is necessary for targeting
of lysosomal hydrolases to the lysosome. Mutations in the gene
encoding the gamma subunit have been associated with mucolipidosis
IIIC, also known as mucolipidosis III gamma.[provided by RefSeq,
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
Transcript exon combination :: AY203933.1, BC014592.1 [ECO:0000332]
RNAseq introns :: single sample supports all introns
COMPLETENESS: complete on the 3' end.