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IKBKG cDNA ORF clone, Homo sapiens (human)

Gene Symbol IKBKG
Entrez Gene ID 8517
Full Name inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
Synonyms AMCBX1, FIP-3, FIP3, Fip3p, IKK-gamma, IMD33, IP, IP1, IP2, IPD2, NEMO, ZC2HC9
General protein information
Preferred Names
NF-kappa-B essential modulator
Names
NF-kappa-B essential modulator
IKKG
IKKAP1
incontinentia pigmenti
IkB kinase gamma subunit
ikB kinase subunit gamma
NFkappaB essential modulator
NF-kappa-B essential modifier
I-kappa-B kinase subunit gamma
ikB kinase-associated protein 1
inhibitor of nuclear factor kappa-B kinase subunit gamma
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

X

Xq28

Summary This gene encodes the regulatory subunit of the inhibitor of kappaB kinase (IKK) complex, which activates NF-kappaB resulting in activation of genes involved in inflammation, immunity, cell survival, and other pathways. Mutations in this gene result in incontinentia pigmenti, hypohidrotic ectodermal dysplasia, and several other types of immunodeficiencies. Multiple transcript variants encoding different isoforms have been found for this gene. A pseudogene highly similar to this locus is located in an adjacent region of the X chromosome. [provided by RefSeq, Aug 2011]. lac of sum
Disorder MIM:

300248

Disorder Html: Incontinentia pigmenti, type II, 308300 (3); Ectodermal dysplasia,

mRNA and Protein(s)

mRNA Protein Name
XM_005274760 XP_005274817 NF-kappa-B essential modulator isoform X2
XM_005274761 XP_005274818 NF-kappa-B essential modulator isoform X3
XM_011531203 XP_011529505 NF-kappa-B essential modulator isoform X4
XM_011531204 XP_011529506 NF-kappa-B essential modulator isoform X1
XM_011531205 XP_011529507 NF-kappa-B essential modulator isoform X1
XM_011531206 XP_011529508 NF-kappa-B essential modulator isoform X5
XM_005274764 XP_005274821 NF-kappa-B essential modulator isoform X6
XM_011531207 XP_011529509 NF-kappa-B essential modulator isoform X7
NM_001099857 NP_001093327 NF-kappa-B essential modulator isoform a
NM_001099856 NP_001093326 NF-kappa-B essential modulator isoform b
NM_003639 NP_003630 NF-kappa-B essential modulator isoform a
NM_001145255 NP_001138727 NF-kappa-B essential modulator isoform c

KEGG
hsa04210 Apoptosis
hsa04010 MAPK signaling pathway
hsa04660 T cell receptor signaling pathway
hsa04620 Toll-like receptor signaling pathway
hsa04662 B cell receptor signaling pathway
hsa05131 Shigellosis
hsa04920 Adipocytokine signaling pathway
hsa05212 Pancreatic cancer
hsa05221 Acute myeloid leukemia
hsa05222 Small cell lung cancer
hsa05120 Epithelial cell signaling in Helicobacter pylori infection
hsa05340 Primary immunodeficiency
hsa05215 Prostate cancer
hsa05220 Chronic myeloid leukemia
hsa05200 Pathways in cancer
hsa04621 NOD-like receptor signaling pathway
hsa04622 RIG-I-like receptor signaling pathway
hsa04623 Cytosolic DNA-sensing pathway
hsa04062 Chemokine signaling pathway
hsa05142 Chagas disease (American trypanosomiasis)
hsa05145 Toxoplasmosis
hsa05160 Hepatitis C
hsa04380 Osteoclast differentiation
hsa05166 HTLV-I infection
hsa05168 Herpes simplex infection
hsa05203 Viral carcinogenesis
hsa04151 PI3K-Akt signaling pathway
hsa05161 Hepatitis B
hsa05169 Epstein-Barr virus infection
hsa04064 NF-kappa B signaling pathway
hsa04668 TNF signaling pathway
hsa04014 Ras signaling pathway
Reactome
R-HSA-1643685 Disease
R-HSA-5602358 Diseases associated with the TLR signaling cascade
R-HSA-1280218 Adaptive Immune System
R-HSA-168256 Immune System
R-HSA-5603027 IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR)
R-HSA-5260271 Diseases of Immune System
R-HSA-5602636 IKBKB deficiency causes SCID
R-HSA-5603029 IkBA variant leads to EDA-ID
R-HSA-1168372 Downstream signaling events of B Cell Receptor (BCR)
R-HSA-202424 Downstream TCR signaling
R-HSA-983705 Signaling by the B Cell Receptor (BCR)
R-HSA-1169091 Activation of NF-kappaB in B cells
R-HSA-202403 TCR signaling
R-HSA-937039 IRAK1 recruits IKK complex
R-HSA-445989 TAK1 activates NFkB by phosphorylation and activation of IKKs complex
R-HSA-168164 Toll Like Receptor 3 (TLR3) Cascade
R-HSA-450302 activated TAK1 mediates p38 MAPK activation
R-HSA-166166 MyD88-independent TLR3/TLR4 cascade
R-HSA-450294 MAP kinase activation in TLR cascade
R-HSA-975871 MyD88 cascade initiated on plasma membrane
R-HSA-168176 Toll Like Receptor 5 (TLR5) Cascade
R-HSA-168898 Toll-Like Receptors Cascades
R-HSA-168142 Toll Like Receptor 10 (TLR10) Cascade
R-HSA-168249 Innate Immune System
R-HSA-937061 TRIF-mediated TLR3/TLR4 signaling
R-HSA-168179 Toll Like Receptor TLR1:TLR2 Cascade
R-HSA-168138 Toll Like Receptor 9 (TLR9) Cascade
R-HSA-975138 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation
R-HSA-181438 Toll Like Receptor 2 (TLR2) Cascade
R-HSA-166016 Toll Like Receptor 4 (TLR4) Cascade
R-HSA-168643 Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways
R-HSA-168638 NOD1/2 Signaling Pathway
R-HSA-168188 Toll Like Receptor TLR6:TLR2 Cascade
R-HSA-933542 TRAF6 mediated NF-kB activation
R-HSA-1606322 ZBP1(DAI) mediated induction of type I IFNs
R-HSA-450321 JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
R-HSA-937041 IKK complex recruitment mediated by RIP1
R-HSA-975144 IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation
R-HSA-166058 MyD88:Mal cascade initiated on plasma membrane
R-HSA-168181 Toll Like Receptor 7/8 (TLR7/8) Cascade
R-HSA-975155 MyD88 dependent cascade initiated on endosome
R-HSA-168928 RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways
R-HSA-933543 NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
R-HSA-166054 Activated TLR4 signalling
R-HSA-1834949 Cytosolic sensors of pathogen-associated DNA
R-HSA-2454202 Fc epsilon receptor (FCERI) signaling
R-HSA-1280215 Cytokine Signaling in Immune system
R-HSA-5621481 C-type lectin receptors (CLRs)
R-HSA-1810476 RIP-mediated NFkB activation via ZBP1
R-HSA-2871837 FCERI mediated NF-kB activation
R-HSA-5607764 CLEC7A (Dectin-1) signaling
R-HSA-446652 Interleukin-1 signaling
R-HSA-449147 Signaling by Interleukins
Pathway Interaction Database
il1pathway IL1-mediated signaling events
trail_pathway TRAIL signaling pathway
tcr_pathway TCR signaling in naive CD4+ T cells
nfkappabcanonicalpathway Canonical NF-kappaB pathway
cd8tcrpathway TCR signaling in naive CD8+ T cells
bcr_5pathway BCR signaling pathway
p75ntrpathway p75(NTR)-mediated signaling
faspathway FAS (CD95) signaling pathway
fcer1pathway Fc-epsilon receptor I signaling in mast cells
tnfpathway TNF receptor signaling pathway
WikiPathways
WP382 MAPK signaling pathway
WP1433 NOD pathway
WP262 EBV LMP1 signaling
WP254 Apoptosis
WP288 NLR proteins
WP1544 MicroRNAs in cardiomyocyte hypertrophy
WP75 Toll-like receptor signaling pathway
WP69 TCR Signaling Pathway
WP231 TNF-alpha/NF-kB Signaling Pathway
WP23 B Cell Receptor Signaling Pathway
WP2018 RANKL/RANK Signaling Pathway
WP2034 Leptin signaling pathway
WP1449 Regulation of toll-like receptor signaling pathway
WP2112 IL17 signaling pathway


Homo sapiens (human) IKBKG NP_001093326.2
Pan troglodytes (chimpanzee) LOC100610002 XP_003317847.1
Macaca mulatta (Rhesus monkey) IKBKG XP_002806492.1
Canis lupus familiaris (dog) IKBKG XP_005642095.1
Bos taurus (cattle) IKBKG XP_005227781.1
Mus musculus (house mouse) Ikbkg NP_001154894.1
Rattus norvegicus (Norway rat) Ikbkg NP_954534.1
Danio rerio (zebrafish) ikbkg NP_001014366.1
Xenopus (Silurana) tropicalis (western clawed frog) ikbkg NP_001120221.1

Component

ID Name Evidence
GO:0005634 nucleus IDA
GO:0005737 cytoplasm IDA
GO:0005829 cytosol EXP
GO:0005829 cytosol TAS
GO:0008385 IkappaB kinase complex TAS
GO:0044444 cytoplasmic part IDA

Function

ID Name Evidence
GO:0004871 signal transducer activity TAS
GO:0005515 protein binding IPI
GO:0019904 protein domain specific binding IPI
GO:0046872 metal ion binding IEA
GO:0046982 protein heterodimerization activity IEA

Process

ID Name Evidence
GO:0000187 activation of MAPK activity TAS
GO:0001782 B cell homeostasis IEA
GO:0002224 toll-like receptor signaling pathway TAS
GO:0002755 MyD88-dependent toll-like receptor signaling pathway EXP
GO:0002755 MyD88-dependent toll-like receptor signaling pathway TAS
GO:0002756 MyD88-independent toll-like receptor signaling pathway EXP
GO:0002756 MyD88-independent toll-like receptor signaling pathway TAS
GO:0006355 regulation of transcription, DNA-dependent IEA
GO:0006917 induction of apoptosis TAS
GO:0006955 immune response TAS
GO:0006974 response to DNA damage stimulus IDA
GO:0007249 I-kappaB kinase/NF-kappaB cascade TAS
GO:0007250 activation of NF-kappaB-inducing kinase activity IEA
GO:0007254 JNK cascade TAS
GO:0008063 Toll signaling pathway TAS
GO:0034130 toll-like receptor 1 signaling pathway TAS
GO:0034134 toll-like receptor 2 signaling pathway TAS
GO:0034138 toll-like receptor 3 signaling pathway TAS
GO:0034142 toll-like receptor 4 signaling pathway TAS
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB cascade TAS
GO:0044419 interspecies interaction between organisms IEA
GO:0045087 innate immune response TAS
GO:0050852 T cell receptor signaling pathway NAS
GO:0050852 T cell receptor signaling pathway TAS
GO:0051092 positive regulation of NF-kappaB transcription factor activity IDA
GO:0051092 positive regulation of NF-kappaB transcription factor activity TAS
GO:0051403 stress-activated MAPK cascade TAS

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following IKBKG gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the IKBKG cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu54455 XM_005274760 PREDICTED: Homo sapiens inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma (IKBKG), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $319.00
OHu54457 XM_005274761 PREDICTED: Homo sapiens inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma (IKBKG), transcript variant X2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $319.00
OHu61910 XM_011531203 PREDICTED: Homo sapiens inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma (IKBKG), transcript variant X3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $319.00
OHu27518
XM_011531204 PREDICTED: Homo sapiens inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma (IKBKG), transcript variant X4, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$223.30
$319.00
OHu27518
XM_011531205 PREDICTED: Homo sapiens inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma (IKBKG), transcript variant X5, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$223.30
$319.00
OHu61911 XM_011531206 PREDICTED: Homo sapiens inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma (IKBKG), transcript variant X6, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $319.00
OHu54458 XM_005274764 PREDICTED: Homo sapiens inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma (IKBKG), transcript variant X7, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $319.00
OHu61912 XM_011531207 PREDICTED: Homo sapiens inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma (IKBKG), transcript variant X8, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $199.00
OHu27518
NM_001099857 Homo sapiens inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma (IKBKG), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$223.30
$319.00
OHu16932 NM_001099856 Homo sapiens inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma (IKBKG), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $319.00
OHu27518
NM_003639 Homo sapiens inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma (IKBKG), transcript variant 3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$223.30
$319.00
OHu27490 NM_001145255 Homo sapiens inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma (IKBKG), transcript variant 4, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $309.00

*Business Day
**You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.


CloneID OHu54455
Accession Version XM_005274760.3 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1461bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product NF-kappa-B essential modulator isoform X2
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_011681.17) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 12, 2015 this sequence version replaced gi:578838942. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
ATGGCCCTTG TGATCCAGGT GGGGAAACTA AGGCCCAGAG AAGTGAGGAC CCCGCAGACT 
ATCAATCCCA GTCTCTTCCC CTCACTCCCT GTGAAGCTCT CCAGCATCAT CGAGGTCCCA
TCAGGTGGGG AAAGATGCTG TTCCAGGCGC ACACTAGTCT ACAAGGCCAG AGCTTTCTGG
AAGGGGGCAC CCTTGCCCTG TTGGATGAAT AGGCACCTCT GGAAGAGCCA ACTGTGTGAG
ATGGTGCAGC CCAGTGGTGG CCCGGCAGCA GATCAGGACG TACTGGGCGA AGAGTCTCCT
CTGGGGAAGC CAGCCATGCT GCACCTGCCT TCAGAACAGG GCGCTCCTGA GACCCTCCAG
CGCTGCCTGG AGGAGAATCA AGAGCTCCGA GATGCCATCC GGCAGAGCAA CCAGATTCTG
CGGGAGCGCT GCGAGGAGCT TCTGCATTTC CAAGCCAGCC AGAGGGAGGA GAAGGAGTTC
CTCATGTGCA AGTTCCAGGA GGCCAGGAAA CTGGTGGAGA GACTCGGCCT GGAGAAGCTC
GATCTGAAGA GGCAGAAGGA GCAGGCTCTG CGGGAGGTGG AGCACCTGAA GAGATGCCAG
CAGATGGCTG AGGACAAGGC CTCTGTGAAA GCCCAGGTGA CGTCCTTGCT CGGGGAGCTG
CAGGAGAGCC AGAGTCGCTT GGAGGCTGCC ACTAAGGAAT GCCAGGCTCT GGAGGGTCGG
GCCCGGGCGG CCAGCGAGCA GGCGCGGCAG CTGGAGAGTG AGCGCGAGGC GCTGCAGCAG
CAGCACAGCG TGCAGGTGGA CCAGCTGCGC ATGCAGGGCC AGAGCGTGGA GGCCGCGCTC
CGCATGGAGC GCCAGGCCGC CTCGGAGGAG AAGAGGAAGC TGGCCCAGTT GCAGGTGGCC
TATCACCAGC TCTTCCAAGA ATACGACAAC CACATCAAGA GCAGCGTGGT GGGCAGTGAG
CGGAAGCGAG GAATGCAGCT GGAAGATCTC AAACAGCAGC TCCAGCAGGC CGAGGAGGCC
CTGGTGGCCA AACAGGAGGT GATCGATAAG CTGAAGGAGG AGGCCGAGCA GCACAAGATT
GTGATGGAGA CCGTTCCGGT GCTGAAGGCC CAGGCGGATA TCTACAAGGC GGACTTCCAG
GCTGAGAGGC AGGCCCGGGA GAAGCTGGCC GAGAAGAAGG AGCTCCTGCA GGAGCAGCTG
GAGCAGCTGC AGAGGGAGTA CAGCAAACTG AAGGCCAGCT GTCAGGAGTC GGCCAGGATC
GAGGACATGA GGAAGCGGCA TGTCGAGGTC TCCCAGGCCC CCTTGCCCCC CGCCCCTGCC
TACCTCTCCT CTCCCCTGGC CCTGCCCAGC CAGAGGAGGA GCCCCCCCGA GGAGCCACCT
GACTTCTGCT GTCCCAAGTG CCAGTATCAG GCCCCTGATA TGGACACCCT GCAGATACAT
GTCATGGAGT GCATTGAGTA G

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeqXP_005274817.1
CDS16..1476
Misc Feature(1)349..552(+)
Misc Feature(2)988..1248(+)
Misc Feature(3)991..1236(+)
Misc Feature(4)1102..1197(+)
Translation
Position Chain Variation Link
226 226 a, c dbSNP:57174646
388 388 a, g dbSNP:148695964
403 403 c, t dbSNP:137853323
484 484 -, gag dbSNP:386134238
556 556 a, g dbSNP:179363896
586 586 c, t dbSNP:179363895
674 674 g, t dbSNP:137853328
686 686 a, c dbSNP:386134240
733 733 c, g dbSNP:179363866
740 740 c, g dbSNP:179363868
896 896 c, t dbSNP:179363869
1079 1079 c, g dbSNP:137853330
1147 1147 a, g dbSNP:179363867
1160 1160 a, c dbSNP:137853331
1172 1172 a, g dbSNP:137853332
1183 1183 c, g dbSNP:179363865
1387 1387 g, t dbSNP:137853324
1423 1423 c, t dbSNP:137853329
1433 1433 a, t dbSNP:137853327
1435 1435 a, g dbSNP:137853322
1465 1465 c, t dbSNP:137853325
1466 1466 a, g, t dbSNP:137853326
1475 1475 a, g dbSNP:137853321

Target ORF information:

RefSeq Version XM_005274760
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma (IKBKG), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_005274760

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
ATGGCCCTTG TGATCCAGGT GGGGAAACTA AGGCCCAGAG AAGTGAGGAC CCCGCAGACT 
ATCAATCCCA GTCTCTTCCC CTCACTCCCT GTGAAGCTCT CCAGCATCAT CGAGGTCCCA
TCAGGTGGGG AAAGATGCTG TTCCAGGCGC ACACTAGTCT ACAAGGCCAG AGCTTTCTGG
AAGGGGGCAC CCTTGCCCTG TTGGATGAAT AGGCACCTCT GGAAGAGCCA ACTGTGTGAG
ATGGTGCAGC CCAGTGGTGG CCCGGCAGCA GATCAGGACG TACTGGGCGA AGAGTCTCCT
CTGGGGAAGC CAGCCATGCT GCACCTGCCT TCAGAACAGG GCGCTCCTGA GACCCTCCAG
CGCTGCCTGG AGGAGAATCA AGAGCTCCGA GATGCCATCC GGCAGAGCAA CCAGATTCTG
CGGGAGCGCT GCGAGGAGCT TCTGCATTTC CAAGCCAGCC AGAGGGAGGA GAAGGAGTTC
CTCATGTGCA AGTTCCAGGA GGCCAGGAAA CTGGTGGAGA GACTCGGCCT GGAGAAGCTC
GATCTGAAGA GGCAGAAGGA GCAGGCTCTG CGGGAGGTGG AGCACCTGAA GAGATGCCAG
CAGATGGCTG AGGACAAGGC CTCTGTGAAA GCCCAGGTGA CGTCCTTGCT CGGGGAGCTG
CAGGAGAGCC AGAGTCGCTT GGAGGCTGCC ACTAAGGAAT GCCAGGCTCT GGAGGGTCGG
GCCCGGGCGG CCAGCGAGCA GGCGCGGCAG CTGGAGAGTG AGCGCGAGGC GCTGCAGCAG
CAGCACAGCG TGCAGGTGGA CCAGCTGCGC ATGCAGGGCC AGAGCGTGGA GGCCGCGCTC
CGCATGGAGC GCCAGGCCGC CTCGGAGGAG AAGAGGAAGC TGGCCCAGTT GCAGGTGGCC
TATCACCAGC TCTTCCAAGA ATACGACAAC CACATCAAGA GCAGCGTGGT GGGCAGTGAG
CGGAAGCGAG GAATGCAGCT GGAAGATCTC AAACAGCAGC TCCAGCAGGC CGAGGAGGCC
CTGGTGGCCA AACAGGAGGT GATCGATAAG CTGAAGGAGG AGGCCGAGCA GCACAAGATT
GTGATGGAGA CCGTTCCGGT GCTGAAGGCC CAGGCGGATA TCTACAAGGC GGACTTCCAG
GCTGAGAGGC AGGCCCGGGA GAAGCTGGCC GAGAAGAAGG AGCTCCTGCA GGAGCAGCTG
GAGCAGCTGC AGAGGGAGTA CAGCAAACTG AAGGCCAGCT GTCAGGAGTC GGCCAGGATC
GAGGACATGA GGAAGCGGCA TGTCGAGGTC TCCCAGGCCC CCTTGCCCCC CGCCCCTGCC
TACCTCTCCT CTCCCCTGGC CCTGCCCAGC CAGAGGAGGA GCCCCCCCGA GGAGCCACCT
GACTTCTGCT GTCCCAAGTG CCAGTATCAG GCCCCTGATA TGGACACCCT GCAGATACAT
GTCATGGAGT GCATTGAGTA G

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu54457
Accession Version XM_005274761.3 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1326bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product NF-kappa-B essential modulator isoform X3
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_011681.17) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 12, 2015 this sequence version replaced gi:578838945. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
ATGGCCCTTG TGATCCAGGT GGGGAAACTA AGGCCCAGAG AAGTGAGGAC CCCGCAGACT 
ATCAATCCCA GTCTCTTCCC CTCACTCCCT GTGAAGCTCT CCAGCATCAT CGAGGTCCCA
TCAGGTGGGG AAAGATGCTG TTCCAGGCGC ACACTAGTCT ACAAGGCCAG AGCTTTCTGG
AAGGGGGCAC CCTTGCCCTG TTGGATGAAT AGGCACCTCT GGAAGAGCCA ACTGTGTGAG
ATGGTGCAGC CCAGTGGTGG CCCGGCAGCA GATCAGGACG TACTGGGCGA AGAGTCTCCT
CTGGGGAAGC CAGCCATGCT GCACCTGCCT TCAGAACAGG GCGCTCCTGA GACCCTCCAG
CGCTGCCTGG AGGAGAATCA AGAGCTCCGA GATGCCATCC GGCAGAGCAA CCAGATTCTG
CGGGAGCGCT GCGAGGAGCT TCTGCATTTC CAAGCCAGCC AGAGGGAGGA GAAGGAGTTC
CTCATGTGCA AGTTCCAGGA GGCCAGGAAA CTGGTGGAGA GACTCGGCCT GGAGAAGCTC
GATCTGAAGA GGCAGAAGGA GCAGGCTCTG CGGGAGGTGG AGCACCTGAA GAGATGCCAG
CAGCAGATGG CTGAGGACAA GGCCTCTGTG AAAGCCCAGG TGACGTCCTT GCTCGGGGAG
CTGCAGGAGA GCCAGAGTCG CTTGGAGGCT GCCACTAAGG AATGCCAGGC TCTGGAGGGT
CGGGCCCGGG CGGCCAGCGA GCAGGCGCGG CAGCTGGAGA GTGAGCGCGA GGCGCTGCAG
CAGCAGCACA GCGTGCAGGT GGACCAGCTG CGCATGCAGG GCCAGAGCGT GGAGGCCGCG
CTCCGCATGG AGCGCCAGGC CGCCTCGGAG GAGAAGAGGA AGCTGGCCCA GTTGCAGGTG
GCCTATCACC AGCTCTTCCA AGAATACGAC AACCACATCA AGAGCAGCGT GGTGGGCAGT
GAGCGGAAGC GAGGAATGCA GCTGGAAGAT CTCAAACAGC AGCTCCAGCA GGCCGAGGAG
GCCCTGGTGG CCAAACAGGA GGTGATCGAT AAGCTGAAGG AGGAGGCCGA GCAGCACAAG
ATTGTGATGG AGACCGTTCC GGTGCTGAAG GCCCAGGCGG ATATCTACAA GGCGGACTTC
CAGGCTGAGA GGCAGGCCCG GGAGAAGCTG GCCGAGAAGA AGGAGCTCCT GCAGGAGCAG
CTGGAGCAGC TGCAGAGGGA GTACAGCAAA CTGAAGGCCA GCTGTCAGGA GTCGGCCAGG
ATCGAGGACA TGAGGAAGCG GCATGTCGAG GTCTCCCAGG CCCCCTTGCC CCCCGCCCCT
GGTTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeqXP_005274818.1
CDS16..1341
Misc Feature(1)349..552(+)
Misc Feature(2)991..1251(+)
Misc Feature(3)994..1239(+)
Misc Feature(4)1105..1200(+)
Translation
Position Chain Variation Link
226 226 a, c dbSNP:57174646
388 388 a, g dbSNP:148695964
403 403 c, t dbSNP:137853323
484 484 -, gag dbSNP:386134238
556 556 a, g dbSNP:179363896
586 586 c, t dbSNP:179363895
677 677 g, t dbSNP:137853328
689 689 a, c dbSNP:386134240
736 736 c, g dbSNP:179363866
743 743 c, g dbSNP:179363868
899 899 c, t dbSNP:179363869
1082 1082 c, g dbSNP:137853330
1150 1150 a, g dbSNP:179363867
1163 1163 a, c dbSNP:137853331
1175 1175 a, g dbSNP:137853332
1186 1186 c, g dbSNP:179363865
1579 1579 a, g dbSNP:4898387

Target ORF information:

RefSeq Version XM_005274761
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma (IKBKG), transcript variant X2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_005274761

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
ATGGCCCTTG TGATCCAGGT GGGGAAACTA AGGCCCAGAG AAGTGAGGAC CCCGCAGACT 
ATCAATCCCA GTCTCTTCCC CTCACTCCCT GTGAAGCTCT CCAGCATCAT CGAGGTCCCA
TCAGGTGGGG AAAGATGCTG TTCCAGGCGC ACACTAGTCT ACAAGGCCAG AGCTTTCTGG
AAGGGGGCAC CCTTGCCCTG TTGGATGAAT AGGCACCTCT GGAAGAGCCA ACTGTGTGAG
ATGGTGCAGC CCAGTGGTGG CCCGGCAGCA GATCAGGACG TACTGGGCGA AGAGTCTCCT
CTGGGGAAGC CAGCCATGCT GCACCTGCCT TCAGAACAGG GCGCTCCTGA GACCCTCCAG
CGCTGCCTGG AGGAGAATCA AGAGCTCCGA GATGCCATCC GGCAGAGCAA CCAGATTCTG
CGGGAGCGCT GCGAGGAGCT TCTGCATTTC CAAGCCAGCC AGAGGGAGGA GAAGGAGTTC
CTCATGTGCA AGTTCCAGGA GGCCAGGAAA CTGGTGGAGA GACTCGGCCT GGAGAAGCTC
GATCTGAAGA GGCAGAAGGA GCAGGCTCTG CGGGAGGTGG AGCACCTGAA GAGATGCCAG
CAGCAGATGG CTGAGGACAA GGCCTCTGTG AAAGCCCAGG TGACGTCCTT GCTCGGGGAG
CTGCAGGAGA GCCAGAGTCG CTTGGAGGCT GCCACTAAGG AATGCCAGGC TCTGGAGGGT
CGGGCCCGGG CGGCCAGCGA GCAGGCGCGG CAGCTGGAGA GTGAGCGCGA GGCGCTGCAG
CAGCAGCACA GCGTGCAGGT GGACCAGCTG CGCATGCAGG GCCAGAGCGT GGAGGCCGCG
CTCCGCATGG AGCGCCAGGC CGCCTCGGAG GAGAAGAGGA AGCTGGCCCA GTTGCAGGTG
GCCTATCACC AGCTCTTCCA AGAATACGAC AACCACATCA AGAGCAGCGT GGTGGGCAGT
GAGCGGAAGC GAGGAATGCA GCTGGAAGAT CTCAAACAGC AGCTCCAGCA GGCCGAGGAG
GCCCTGGTGG CCAAACAGGA GGTGATCGAT AAGCTGAAGG AGGAGGCCGA GCAGCACAAG
ATTGTGATGG AGACCGTTCC GGTGCTGAAG GCCCAGGCGG ATATCTACAA GGCGGACTTC
CAGGCTGAGA GGCAGGCCCG GGAGAAGCTG GCCGAGAAGA AGGAGCTCCT GCAGGAGCAG
CTGGAGCAGC TGCAGAGGGA GTACAGCAAA CTGAAGGCCA GCTGTCAGGA GTCGGCCAGG
ATCGAGGACA TGAGGAAGCG GCATGTCGAG GTCTCCCAGG CCCCCTTGCC CCCCGCCCCT
GGTTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu61910
Accession Version XM_011531203.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1311bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product NF-kappa-B essential modulator isoform X4
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_011681.17) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
ATGGCCCTTG TGATCCAGGT GGGGAAACTA AGGCCCAGAG AAGTGAGGAC CCCGCAGACT 
ATCAATCCCA GTCTCTTCCC CTCACTCCCT GTGAAGCTCT CCAGCATCAT CGAGGTCCCA
TCAGGTGGGG AAAGATGCTG TTCCAGGCGC ACACTAGTCT ACAAGGCCAG AGCTTTCTGG
AAGGGGGCAC CCTTGCCCTG TTGGATGAAT AGGCACCTCT GGAAGAGCCA ACTGTGTGAG
ATGGTGCAGC CCAGTGGTGG CCCGGCAGCA GATCAGGACG TACTGGGCGA AGAGTCTCCT
CTGGGGAAGC CAGCCATGCT GCACCTGCCT TCAGAACAGG GCGCTCCTGA GACCCTCCAG
CGCTGCCTGG AGGAGAATCA AGAGCTCCGA GATGCCATCC GGCAGAGCAA CCAGATTCTG
CGGGAGCGCT GCGAGGAGCT TCTGCATTTC CAAGCCAGCC AGAGGGAGGA GAAGGAGTTC
CTCATGTGCA AGTTCCAGGA GGCCAGGAAA CTGGTGGAGA GACTCGGCCT GGAGAAGCTC
GATCTGAAGA GGCAGAAGGA GCAGGCTCTG CGGGAGGTGG AGCACCTGAA GAGATGCCAG
CAGCAGATGG CTGAGGACAA GGCCTCTGTG AAAGCCCAGG TGACGTCCTT GCTCGGGGAG
CTGCAGGAGA GCCAGAGTCG CTTGGAGGCT GCCACTAAGG AATGCCAGGC TCTGGAGGGT
CGGAGGAAGC TGGCCCAGTT GCAGGTGGCC TATCACCAGC TCTTCCAAGA ATACGACAAC
CACATCAAGA GCAGCGTGGT GGGCAGTGAG CGGAAGCGAG GAATGCAGCT GGAAGATCTC
AAACAGCAGC TCCAGCAGGC CGAGGAGGCC CTGGTGGCCA AACAGGAGGT GATCGATAAG
CTGAAGGAGG AGGCCGAGCA GCACAAGATT GTGATGGAGA CCGTTCCGGT GCTGAAGGCC
CAGGCGGATA TCTACAAGGC GGACTTCCAG GCTGAGAGGC AGGCCCGGGA GAAGCTGGCC
GAGAAGAAGG AGCTCCTGCA GGAGCAGCTG GAGCAGCTGC AGAGGGAGTA CAGCAAACTG
AAGGCCAGCT GTCAGGAGTC GGCCAGGATC GAGGACATGA GGAAGCGGCA TGTCGAGGTC
TCCCAGGCCC CCTTGCCCCC CGCCCCTGCC TACCTCTCCT CTCCCCTGGC CCTGCCCAGC
CAGAGGAGGA GCCCCCCCGA GGAGCCACCT GACTTCTGCT GTCCCAAGTG CCAGTATCAG
GCCCCTGATA TGGACACCCT GCAGATACAT GTCATGGAGT GCATTGAGTA G

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeqXP_011529505.1
CDS16..1326
Misc Feature(1)349..552(+)
Misc Feature(2)574..990(+)
Misc Feature(3)838..1098(+)
Misc Feature(4)841..1086(+)
Misc Feature(5)952..1047(+)
Translation
Position Chain Variation Link
226 226 a, c dbSNP:57174646
388 388 a, g dbSNP:148695964
403 403 c, t dbSNP:137853323
484 484 -, gag dbSNP:386134238
556 556 a, g dbSNP:179363896
586 586 c, t dbSNP:179363895
677 677 g, t dbSNP:137853328
689 689 a, c dbSNP:386134240
736 736 c, g dbSNP:179363866
746 746 c, t dbSNP:179363869
929 929 c, g dbSNP:137853330
997 997 a, g dbSNP:179363867
1010 1010 a, c dbSNP:137853331
1022 1022 a, g dbSNP:137853332
1033 1033 c, g dbSNP:179363865
1237 1237 g, t dbSNP:137853324
1273 1273 c, t dbSNP:137853329
1283 1283 a, t dbSNP:137853327
1285 1285 a, g dbSNP:137853322
1315 1315 c, t dbSNP:137853325
1316 1316 a, g, t dbSNP:137853326
1325 1325 a, g dbSNP:137853321

Target ORF information:

RefSeq Version XM_011531203
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma (IKBKG), transcript variant X3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011531203

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
ATGGCCCTTG TGATCCAGGT GGGGAAACTA AGGCCCAGAG AAGTGAGGAC CCCGCAGACT 
ATCAATCCCA GTCTCTTCCC CTCACTCCCT GTGAAGCTCT CCAGCATCAT CGAGGTCCCA
TCAGGTGGGG AAAGATGCTG TTCCAGGCGC ACACTAGTCT ACAAGGCCAG AGCTTTCTGG
AAGGGGGCAC CCTTGCCCTG TTGGATGAAT AGGCACCTCT GGAAGAGCCA ACTGTGTGAG
ATGGTGCAGC CCAGTGGTGG CCCGGCAGCA GATCAGGACG TACTGGGCGA AGAGTCTCCT
CTGGGGAAGC CAGCCATGCT GCACCTGCCT TCAGAACAGG GCGCTCCTGA GACCCTCCAG
CGCTGCCTGG AGGAGAATCA AGAGCTCCGA GATGCCATCC GGCAGAGCAA CCAGATTCTG
CGGGAGCGCT GCGAGGAGCT TCTGCATTTC CAAGCCAGCC AGAGGGAGGA GAAGGAGTTC
CTCATGTGCA AGTTCCAGGA GGCCAGGAAA CTGGTGGAGA GACTCGGCCT GGAGAAGCTC
GATCTGAAGA GGCAGAAGGA GCAGGCTCTG CGGGAGGTGG AGCACCTGAA GAGATGCCAG
CAGCAGATGG CTGAGGACAA GGCCTCTGTG AAAGCCCAGG TGACGTCCTT GCTCGGGGAG
CTGCAGGAGA GCCAGAGTCG CTTGGAGGCT GCCACTAAGG AATGCCAGGC TCTGGAGGGT
CGGAGGAAGC TGGCCCAGTT GCAGGTGGCC TATCACCAGC TCTTCCAAGA ATACGACAAC
CACATCAAGA GCAGCGTGGT GGGCAGTGAG CGGAAGCGAG GAATGCAGCT GGAAGATCTC
AAACAGCAGC TCCAGCAGGC CGAGGAGGCC CTGGTGGCCA AACAGGAGGT GATCGATAAG
CTGAAGGAGG AGGCCGAGCA GCACAAGATT GTGATGGAGA CCGTTCCGGT GCTGAAGGCC
CAGGCGGATA TCTACAAGGC GGACTTCCAG GCTGAGAGGC AGGCCCGGGA GAAGCTGGCC
GAGAAGAAGG AGCTCCTGCA GGAGCAGCTG GAGCAGCTGC AGAGGGAGTA CAGCAAACTG
AAGGCCAGCT GTCAGGAGTC GGCCAGGATC GAGGACATGA GGAAGCGGCA TGTCGAGGTC
TCCCAGGCCC CCTTGCCCCC CGCCCCTGCC TACCTCTCCT CTCCCCTGGC CCTGCCCAGC
CAGAGGAGGA GCCCCCCCGA GGAGCCACCT GACTTCTGCT GTCCCAAGTG CCAGTATCAG
GCCCCTGATA TGGACACCCT GCAGATACAT GTCATGGAGT GCATTGAGTA G

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu27518
Accession Version XM_011531204.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1260bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product NF-kappa-B essential modulator isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_011681.17) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
ATGAATAGGC ACCTCTGGAA GAGCCAACTG TGTGAGATGG TGCAGCCCAG TGGTGGCCCG 
GCAGCAGATC AGGACGTACT GGGCGAAGAG TCTCCTCTGG GGAAGCCAGC CATGCTGCAC
CTGCCTTCAG AACAGGGCGC TCCTGAGACC CTCCAGCGCT GCCTGGAGGA GAATCAAGAG
CTCCGAGATG CCATCCGGCA GAGCAACCAG ATTCTGCGGG AGCGCTGCGA GGAGCTTCTG
CATTTCCAAG CCAGCCAGAG GGAGGAGAAG GAGTTCCTCA TGTGCAAGTT CCAGGAGGCC
AGGAAACTGG TGGAGAGACT CGGCCTGGAG AAGCTCGATC TGAAGAGGCA GAAGGAGCAG
GCTCTGCGGG AGGTGGAGCA CCTGAAGAGA TGCCAGCAGC AGATGGCTGA GGACAAGGCC
TCTGTGAAAG CCCAGGTGAC GTCCTTGCTC GGGGAGCTGC AGGAGAGCCA GAGTCGCTTG
GAGGCTGCCA CTAAGGAATG CCAGGCTCTG GAGGGTCGGG CCCGGGCGGC CAGCGAGCAG
GCGCGGCAGC TGGAGAGTGA GCGCGAGGCG CTGCAGCAGC AGCACAGCGT GCAGGTGGAC
CAGCTGCGCA TGCAGGGCCA GAGCGTGGAG GCCGCGCTCC GCATGGAGCG CCAGGCCGCC
TCGGAGGAGA AGAGGAAGCT GGCCCAGTTG CAGGTGGCCT ATCACCAGCT CTTCCAAGAA
TACGACAACC ACATCAAGAG CAGCGTGGTG GGCAGTGAGC GGAAGCGAGG AATGCAGCTG
GAAGATCTCA AACAGCAGCT CCAGCAGGCC GAGGAGGCCC TGGTGGCCAA ACAGGAGGTG
ATCGATAAGC TGAAGGAGGA GGCCGAGCAG CACAAGATTG TGATGGAGAC CGTTCCGGTG
CTGAAGGCCC AGGCGGATAT CTACAAGGCG GACTTCCAGG CTGAGAGGCA GGCCCGGGAG
AAGCTGGCCG AGAAGAAGGA GCTCCTGCAG GAGCAGCTGG AGCAGCTGCA GAGGGAGTAC
AGCAAACTGA AGGCCAGCTG TCAGGAGTCG GCCAGGATCG AGGACATGAG GAAGCGGCAT
GTCGAGGTCT CCCAGGCCCC CTTGCCCCCC GCCCCTGCCT ACCTCTCCTC TCCCCTGGCC
CTGCCCAGCC AGAGGAGGAG CCCCCCCGAG GAGCCACCTG ACTTCTGCTG TCCCAAGTGC
CAGTATCAGG CCCCTGATAT GGACACCCTG CAGATACATG TCATGGAGTG CATTGAGTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeqXP_011529506.1
CDS204..1463
Misc Feature(1)333..536(+)
Misc Feature(2)975..1235(+)
Misc Feature(3)978..1223(+)
Misc Feature(4)1089..1184(+)
Translation
Position Chain Variation Link
210 210 a, c dbSNP:57174646
372 372 a, g dbSNP:148695964
387 387 c, t dbSNP:137853323
468 468 -, gag dbSNP:386134238
540 540 a, g dbSNP:179363896
570 570 c, t dbSNP:179363895
661 661 g, t dbSNP:137853328
673 673 a, c dbSNP:386134240
720 720 c, g dbSNP:179363866
727 727 c, g dbSNP:179363868
883 883 c, t dbSNP:179363869
1066 1066 c, g dbSNP:137853330
1134 1134 a, g dbSNP:179363867
1147 1147 a, c dbSNP:137853331
1159 1159 a, g dbSNP:137853332
1170 1170 c, g dbSNP:179363865
1374 1374 g, t dbSNP:137853324
1410 1410 c, t dbSNP:137853329
1420 1420 a, t dbSNP:137853327
1422 1422 a, g dbSNP:137853322
1452 1452 c, t dbSNP:137853325
1453 1453 a, g, t dbSNP:137853326
1462 1462 a, g dbSNP:137853321

Target ORF information:

RefSeq Version XM_011531204
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma (IKBKG), transcript variant X4, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011531204

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
ATGAATAGGC ACCTCTGGAA GAGCCAACTG TGTGAGATGG TGCAGCCCAG TGGTGGCCCG 
GCAGCAGATC AGGACGTACT GGGCGAAGAG TCTCCTCTGG GGAAGCCAGC CATGCTGCAC
CTGCCTTCAG AACAGGGCGC TCCTGAGACC CTCCAGCGCT GCCTGGAGGA GAATCAAGAG
CTCCGAGATG CCATCCGGCA GAGCAACCAG ATTCTGCGGG AGCGCTGCGA GGAGCTTCTG
CATTTCCAAG CCAGCCAGAG GGAGGAGAAG GAGTTCCTCA TGTGCAAGTT CCAGGAGGCC
AGGAAACTGG TGGAGAGACT CGGCCTGGAG AAGCTCGATC TGAAGAGGCA GAAGGAGCAG
GCTCTGCGGG AGGTGGAGCA CCTGAAGAGA TGCCAGCAGC AGATGGCTGA GGACAAGGCC
TCTGTGAAAG CCCAGGTGAC GTCCTTGCTC GGGGAGCTGC AGGAGAGCCA GAGTCGCTTG
GAGGCTGCCA CTAAGGAATG CCAGGCTCTG GAGGGTCGGG CCCGGGCGGC CAGCGAGCAG
GCGCGGCAGC TGGAGAGTGA GCGCGAGGCG CTGCAGCAGC AGCACAGCGT GCAGGTGGAC
CAGCTGCGCA TGCAGGGCCA GAGCGTGGAG GCCGCGCTCC GCATGGAGCG CCAGGCCGCC
TCGGAGGAGA AGAGGAAGCT GGCCCAGTTG CAGGTGGCCT ATCACCAGCT CTTCCAAGAA
TACGACAACC ACATCAAGAG CAGCGTGGTG GGCAGTGAGC GGAAGCGAGG AATGCAGCTG
GAAGATCTCA AACAGCAGCT CCAGCAGGCC GAGGAGGCCC TGGTGGCCAA ACAGGAGGTG
ATCGATAAGC TGAAGGAGGA GGCCGAGCAG CACAAGATTG TGATGGAGAC CGTTCCGGTG
CTGAAGGCCC AGGCGGATAT CTACAAGGCG GACTTCCAGG CTGAGAGGCA GGCCCGGGAG
AAGCTGGCCG AGAAGAAGGA GCTCCTGCAG GAGCAGCTGG AGCAGCTGCA GAGGGAGTAC
AGCAAACTGA AGGCCAGCTG TCAGGAGTCG GCCAGGATCG AGGACATGAG GAAGCGGCAT
GTCGAGGTCT CCCAGGCCCC CTTGCCCCCC GCCCCTGCCT ACCTCTCCTC TCCCCTGGCC
CTGCCCAGCC AGAGGAGGAG CCCCCCCGAG GAGCCACCTG ACTTCTGCTG TCCCAAGTGC
CAGTATCAGG CCCCTGATAT GGACACCCTG CAGATACATG TCATGGAGTG CATTGAGTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu27518
Accession Version XM_011531205.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1260bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product NF-kappa-B essential modulator isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_011681.17) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
ATGAATAGGC ACCTCTGGAA GAGCCAACTG TGTGAGATGG TGCAGCCCAG TGGTGGCCCG 
GCAGCAGATC AGGACGTACT GGGCGAAGAG TCTCCTCTGG GGAAGCCAGC CATGCTGCAC
CTGCCTTCAG AACAGGGCGC TCCTGAGACC CTCCAGCGCT GCCTGGAGGA GAATCAAGAG
CTCCGAGATG CCATCCGGCA GAGCAACCAG ATTCTGCGGG AGCGCTGCGA GGAGCTTCTG
CATTTCCAAG CCAGCCAGAG GGAGGAGAAG GAGTTCCTCA TGTGCAAGTT CCAGGAGGCC
AGGAAACTGG TGGAGAGACT CGGCCTGGAG AAGCTCGATC TGAAGAGGCA GAAGGAGCAG
GCTCTGCGGG AGGTGGAGCA CCTGAAGAGA TGCCAGCAGC AGATGGCTGA GGACAAGGCC
TCTGTGAAAG CCCAGGTGAC GTCCTTGCTC GGGGAGCTGC AGGAGAGCCA GAGTCGCTTG
GAGGCTGCCA CTAAGGAATG CCAGGCTCTG GAGGGTCGGG CCCGGGCGGC CAGCGAGCAG
GCGCGGCAGC TGGAGAGTGA GCGCGAGGCG CTGCAGCAGC AGCACAGCGT GCAGGTGGAC
CAGCTGCGCA TGCAGGGCCA GAGCGTGGAG GCCGCGCTCC GCATGGAGCG CCAGGCCGCC
TCGGAGGAGA AGAGGAAGCT GGCCCAGTTG CAGGTGGCCT ATCACCAGCT CTTCCAAGAA
TACGACAACC ACATCAAGAG CAGCGTGGTG GGCAGTGAGC GGAAGCGAGG AATGCAGCTG
GAAGATCTCA AACAGCAGCT CCAGCAGGCC GAGGAGGCCC TGGTGGCCAA ACAGGAGGTG
ATCGATAAGC TGAAGGAGGA GGCCGAGCAG CACAAGATTG TGATGGAGAC CGTTCCGGTG
CTGAAGGCCC AGGCGGATAT CTACAAGGCG GACTTCCAGG CTGAGAGGCA GGCCCGGGAG
AAGCTGGCCG AGAAGAAGGA GCTCCTGCAG GAGCAGCTGG AGCAGCTGCA GAGGGAGTAC
AGCAAACTGA AGGCCAGCTG TCAGGAGTCG GCCAGGATCG AGGACATGAG GAAGCGGCAT
GTCGAGGTCT CCCAGGCCCC CTTGCCCCCC GCCCCTGCCT ACCTCTCCTC TCCCCTGGCC
CTGCCCAGCC AGAGGAGGAG CCCCCCCGAG GAGCCACCTG ACTTCTGCTG TCCCAAGTGC
CAGTATCAGG CCCCTGATAT GGACACCCTG CAGATACATG TCATGGAGTG CATTGAGTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeqXP_011529507.1
CDS348..1607
Misc Feature(1)477..680(+)
Misc Feature(2)1119..1379(+)
Misc Feature(3)1122..1367(+)
Misc Feature(4)1233..1328(+)
Translation
Position Chain Variation Link
354 354 a, c dbSNP:57174646
516 516 a, g dbSNP:148695964
531 531 c, t dbSNP:137853323
612 612 -, gag dbSNP:386134238
684 684 a, g dbSNP:179363896
714 714 c, t dbSNP:179363895
805 805 g, t dbSNP:137853328
817 817 a, c dbSNP:386134240
864 864 c, g dbSNP:179363866
871 871 c, g dbSNP:179363868
1027 1027 c, t dbSNP:179363869
1210 1210 c, g dbSNP:137853330
1278 1278 a, g dbSNP:179363867
1291 1291 a, c dbSNP:137853331
1303 1303 a, g dbSNP:137853332
1314 1314 c, g dbSNP:179363865
1518 1518 g, t dbSNP:137853324
1554 1554 c, t dbSNP:137853329
1564 1564 a, t dbSNP:137853327
1566 1566 a, g dbSNP:137853322
1596 1596 c, t dbSNP:137853325
1597 1597 a, g, t dbSNP:137853326
1606 1606 a, g dbSNP:137853321

Target ORF information:

RefSeq Version XM_011531205
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma (IKBKG), transcript variant X5, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011531205

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
ATGAATAGGC ACCTCTGGAA GAGCCAACTG TGTGAGATGG TGCAGCCCAG TGGTGGCCCG 
GCAGCAGATC AGGACGTACT GGGCGAAGAG TCTCCTCTGG GGAAGCCAGC CATGCTGCAC
CTGCCTTCAG AACAGGGCGC TCCTGAGACC CTCCAGCGCT GCCTGGAGGA GAATCAAGAG
CTCCGAGATG CCATCCGGCA GAGCAACCAG ATTCTGCGGG AGCGCTGCGA GGAGCTTCTG
CATTTCCAAG CCAGCCAGAG GGAGGAGAAG GAGTTCCTCA TGTGCAAGTT CCAGGAGGCC
AGGAAACTGG TGGAGAGACT CGGCCTGGAG AAGCTCGATC TGAAGAGGCA GAAGGAGCAG
GCTCTGCGGG AGGTGGAGCA CCTGAAGAGA TGCCAGCAGC AGATGGCTGA GGACAAGGCC
TCTGTGAAAG CCCAGGTGAC GTCCTTGCTC GGGGAGCTGC AGGAGAGCCA GAGTCGCTTG
GAGGCTGCCA CTAAGGAATG CCAGGCTCTG GAGGGTCGGG CCCGGGCGGC CAGCGAGCAG
GCGCGGCAGC TGGAGAGTGA GCGCGAGGCG CTGCAGCAGC AGCACAGCGT GCAGGTGGAC
CAGCTGCGCA TGCAGGGCCA GAGCGTGGAG GCCGCGCTCC GCATGGAGCG CCAGGCCGCC
TCGGAGGAGA AGAGGAAGCT GGCCCAGTTG CAGGTGGCCT ATCACCAGCT CTTCCAAGAA
TACGACAACC ACATCAAGAG CAGCGTGGTG GGCAGTGAGC GGAAGCGAGG AATGCAGCTG
GAAGATCTCA AACAGCAGCT CCAGCAGGCC GAGGAGGCCC TGGTGGCCAA ACAGGAGGTG
ATCGATAAGC TGAAGGAGGA GGCCGAGCAG CACAAGATTG TGATGGAGAC CGTTCCGGTG
CTGAAGGCCC AGGCGGATAT CTACAAGGCG GACTTCCAGG CTGAGAGGCA GGCCCGGGAG
AAGCTGGCCG AGAAGAAGGA GCTCCTGCAG GAGCAGCTGG AGCAGCTGCA GAGGGAGTAC
AGCAAACTGA AGGCCAGCTG TCAGGAGTCG GCCAGGATCG AGGACATGAG GAAGCGGCAT
GTCGAGGTCT CCCAGGCCCC CTTGCCCCCC GCCCCTGCCT ACCTCTCCTC TCCCCTGGCC
CTGCCCAGCC AGAGGAGGAG CCCCCCCGAG GAGCCACCTG ACTTCTGCTG TCCCAAGTGC
CAGTATCAGG CCCCTGATAT GGACACCCTG CAGATACATG TCATGGAGTG CATTGAGTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu61911
Accession Version XM_011531206.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1242bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product NF-kappa-B essential modulator isoform X5
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_011681.17) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
ATGGCCCTTG TGATCCAGGT GGGGAAACTA AGGCCCAGAG AAGTGAGGAC CCCGCAGACT 
ATCAATCCCA GTCTCTTCCC CTCACTCCCT GTGAAGCTCT CCAGCATCAT CGAGGTCCCA
TCAGGTGGGG AAAGATGCTG TTCCAGGCGC ACACTAGTCT ACAAGGCCAG AGCTTTCTGG
AAGGGGGCAC CCTTGCCCTG TTGGATGAAT AGGCACCTCT GGAAGAGCCA ACTGTGTGAG
ATGGTGCAGC CCAGTGGTGG CCCGGCAGCA GATCAGGACG TACTGGGCGA AGAGTCTCCT
CTGGGGAAGC CAGCCATGCT GCACCTGCCT TCAGAACAGG GCGCTCCTGA GACCCTCCAG
CGCTGCCTGG AGGAGAATCA AGAGCTCCGA GATGCCATCC GGCAGAGCAA CCAGATTCTG
CGGGAGCGCT GCGAGGAGCT TCTGCATTTC CAAGCCAGCC AGAGGGAGGA GAAGGAGTTC
CTCATGTGCA AGTTCCAGGA GGCCAGGAAA CTGGTGGAGA GACTCGGCCT GGAGAAGCTC
GATCTGAAGA GGCAGAAGGA GCAGGCTCTG CGGGAGGTGG AGCACCTGAA GAGATGCCAG
CAGCAGATGG CTGAGGACAA GGCCTCTGTG AAAGCCCAGG TGACGTCCTT GCTCGGGGAG
CTGCAGGAGA GCCAGAGTCG CTTGGAGGCT GCCACTAAGG AATGCCAGGC TCTGGAGGGT
CGACAGATGG ATCAGCTGCC AGGGGGGCCC CAGCCATCCC AGCACAGTAG GCGGTCAAGG
TGCACTTGGG GCAGCCAGCA GGGCAGAGGG GAGGGGAGCT TGACCCAGGC TCTGATGGGC
AGAGGGAACC CGTGCAGGGT GTGGGGGCAG TATGCAGGCA GGCGCGGAGG GGAGAGCCAA
GCAGCCAGGC CTGCCAGGCA GAGTTGGGGT GACTGGAGAA GGGCCGTGTC TGCCTGTGGC
CAGAGGCCAC CCAGGACCTG GACAGATGCA CCCACCATTG TCCCTGCAGT GAGGCTGTGG
AAGGGCTTGG TGTGGTGGGA TGAGGCCAGA CCCTGGAAAC TGGAGGTTAA GGGAGCTGTA
GGGGGGCAGG TGTGGGAACT GAGCATCCGA GCAGGTCGTC TGGGACTCCA GCAGAGCTCT
GGGCAGCAGC AGGGATGGGG CCGAGGCCCG GTCTGCATTG AGCTCAGTGC TTGCACGCCC
AGGTGGGCAG TCTCTCATTT TTGGAACAGC AGTCTCTCCT GA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeqXP_011529508.1
CDS35..1276
Misc Feature(1)368..571(+)
Translation
Position Chain Variation Link
245 245 a, c dbSNP:57174646
407 407 a, g dbSNP:148695964
422 422 c, t dbSNP:137853323
503 503 -, gag dbSNP:386134238
575 575 a, g dbSNP:179363896
605 605 c, t dbSNP:179363895
696 696 g, t dbSNP:137853328
708 708 a, c dbSNP:386134240
755 755 c, g dbSNP:179363866

Target ORF information:

RefSeq Version XM_011531206
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma (IKBKG), transcript variant X6, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011531206

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
ATGGCCCTTG TGATCCAGGT GGGGAAACTA AGGCCCAGAG AAGTGAGGAC CCCGCAGACT 
ATCAATCCCA GTCTCTTCCC CTCACTCCCT GTGAAGCTCT CCAGCATCAT CGAGGTCCCA
TCAGGTGGGG AAAGATGCTG TTCCAGGCGC ACACTAGTCT ACAAGGCCAG AGCTTTCTGG
AAGGGGGCAC CCTTGCCCTG TTGGATGAAT AGGCACCTCT GGAAGAGCCA ACTGTGTGAG
ATGGTGCAGC CCAGTGGTGG CCCGGCAGCA GATCAGGACG TACTGGGCGA AGAGTCTCCT
CTGGGGAAGC CAGCCATGCT GCACCTGCCT TCAGAACAGG GCGCTCCTGA GACCCTCCAG
CGCTGCCTGG AGGAGAATCA AGAGCTCCGA GATGCCATCC GGCAGAGCAA CCAGATTCTG
CGGGAGCGCT GCGAGGAGCT TCTGCATTTC CAAGCCAGCC AGAGGGAGGA GAAGGAGTTC
CTCATGTGCA AGTTCCAGGA GGCCAGGAAA CTGGTGGAGA GACTCGGCCT GGAGAAGCTC
GATCTGAAGA GGCAGAAGGA GCAGGCTCTG CGGGAGGTGG AGCACCTGAA GAGATGCCAG
CAGCAGATGG CTGAGGACAA GGCCTCTGTG AAAGCCCAGG TGACGTCCTT GCTCGGGGAG
CTGCAGGAGA GCCAGAGTCG CTTGGAGGCT GCCACTAAGG AATGCCAGGC TCTGGAGGGT
CGACAGATGG ATCAGCTGCC AGGGGGGCCC CAGCCATCCC AGCACAGTAG GCGGTCAAGG
TGCACTTGGG GCAGCCAGCA GGGCAGAGGG GAGGGGAGCT TGACCCAGGC TCTGATGGGC
AGAGGGAACC CGTGCAGGGT GTGGGGGCAG TATGCAGGCA GGCGCGGAGG GGAGAGCCAA
GCAGCCAGGC CTGCCAGGCA GAGTTGGGGT GACTGGAGAA GGGCCGTGTC TGCCTGTGGC
CAGAGGCCAC CCAGGACCTG GACAGATGCA CCCACCATTG TCCCTGCAGT GAGGCTGTGG
AAGGGCTTGG TGTGGTGGGA TGAGGCCAGA CCCTGGAAAC TGGAGGTTAA GGGAGCTGTA
GGGGGGCAGG TGTGGGAACT GAGCATCCGA GCAGGTCGTC TGGGACTCCA GCAGAGCTCT
GGGCAGCAGC AGGGATGGGG CCGAGGCCCG GTCTGCATTG AGCTCAGTGC TTGCACGCCC
AGGTGGGCAG TCTCTCATTT TTGGAACAGC AGTCTCTCCT GA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu54458
Accession Version XM_005274764.3 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1257bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product NF-kappa-B essential modulator isoform X6
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_011681.17) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 12, 2015 this sequence version replaced gi:578838947. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
ATGAATAGGC ACCTCTGGAA GAGCCAACTG TGTGAGATGG TGCAGCCCAG TGGTGGCCCG 
GCAGCAGATC AGGACGTACT GGGCGAAGAG TCTCCTCTGG GGAAGCCAGC CATGCTGCAC
CTGCCTTCAG AACAGGGCGC TCCTGAGACC CTCCAGCGCT GCCTGGAGGA GAATCAAGAG
CTCCGAGATG CCATCCGGCA GAGCAACCAG ATTCTGCGGG AGCGCTGCGA GGAGCTTCTG
CATTTCCAAG CCAGCCAGAG GGAGGAGAAG GAGTTCCTCA TGTGCAAGTT CCAGGAGGCC
AGGAAACTGG TGGAGAGACT CGGCCTGGAG AAGCTCGATC TGAAGAGGCA GAAGGAGCAG
GCTCTGCGGG AGGTGGAGCA CCTGAAGAGA TGCCAGCAGA TGGCTGAGGA CAAGGCCTCT
GTGAAAGCCC AGGTGACGTC CTTGCTCGGG GAGCTGCAGG AGAGCCAGAG TCGCTTGGAG
GCTGCCACTA AGGAATGCCA GGCTCTGGAG GGTCGGGCCC GGGCGGCCAG CGAGCAGGCG
CGGCAGCTGG AGAGTGAGCG CGAGGCGCTG CAGCAGCAGC ACAGCGTGCA GGTGGACCAG
CTGCGCATGC AGGGCCAGAG CGTGGAGGCC GCGCTCCGCA TGGAGCGCCA GGCCGCCTCG
GAGGAGAAGA GGAAGCTGGC CCAGTTGCAG GTGGCCTATC ACCAGCTCTT CCAAGAATAC
GACAACCACA TCAAGAGCAG CGTGGTGGGC AGTGAGCGGA AGCGAGGAAT GCAGCTGGAA
GATCTCAAAC AGCAGCTCCA GCAGGCCGAG GAGGCCCTGG TGGCCAAACA GGAGGTGATC
GATAAGCTGA AGGAGGAGGC CGAGCAGCAC AAGATTGTGA TGGAGACCGT TCCGGTGCTG
AAGGCCCAGG CGGATATCTA CAAGGCGGAC TTCCAGGCTG AGAGGCAGGC CCGGGAGAAG
CTGGCCGAGA AGAAGGAGCT CCTGCAGGAG CAGCTGGAGC AGCTGCAGAG GGAGTACAGC
AAACTGAAGG CCAGCTGTCA GGAGTCGGCC AGGATCGAGG ACATGAGGAA GCGGCATGTC
GAGGTCTCCC AGGCCCCCTT GCCCCCCGCC CCTGCCTACC TCTCCTCTCC CCTGGCCCTG
CCCAGCCAGA GGAGGAGCCC CCCCGAGGAG CCACCTGACT TCTGCTGTCC CAAGTGCCAG
TATCAGGCCC CTGATATGGA CACCCTGCAG ATACATGTCA TGGAGTGCAT TGAGTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeqXP_005274821.1
CDS294..1550
Misc Feature(1)423..626(+)
Misc Feature(2)1062..1322(+)
Misc Feature(3)1065..1310(+)
Misc Feature(4)1176..1271(+)
Translation
Position Chain Variation Link
103 103 c, t dbSNP:111827785
300 300 a, c dbSNP:57174646
462 462 a, g dbSNP:148695964
477 477 c, t dbSNP:137853323
558 558 -, gag dbSNP:386134238
630 630 a, g dbSNP:179363896
660 660 c, t dbSNP:179363895
748 748 g, t dbSNP:137853328
760 760 a, c dbSNP:386134240
807 807 c, g dbSNP:179363866
814 814 c, g dbSNP:179363868
970 970 c, t dbSNP:179363869
1153 1153 c, g dbSNP:137853330
1221 1221 a, g dbSNP:179363867
1234 1234 a, c dbSNP:137853331
1246 1246 a, g dbSNP:137853332
1257 1257 c, g dbSNP:179363865
1461 1461 g, t dbSNP:137853324
1497 1497 c, t dbSNP:137853329
1507 1507 a, t dbSNP:137853327
1509 1509 a, g dbSNP:137853322
1539 1539 c, t dbSNP:137853325
1540 1540 a, g, t dbSNP:137853326
1549 1549 a, g dbSNP:137853321

Target ORF information:

RefSeq Version XM_005274764
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma (IKBKG), transcript variant X7, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_005274764

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
ATGAATAGGC ACCTCTGGAA GAGCCAACTG TGTGAGATGG TGCAGCCCAG TGGTGGCCCG 
GCAGCAGATC AGGACGTACT GGGCGAAGAG TCTCCTCTGG GGAAGCCAGC CATGCTGCAC
CTGCCTTCAG AACAGGGCGC TCCTGAGACC CTCCAGCGCT GCCTGGAGGA GAATCAAGAG
CTCCGAGATG CCATCCGGCA GAGCAACCAG ATTCTGCGGG AGCGCTGCGA GGAGCTTCTG
CATTTCCAAG CCAGCCAGAG GGAGGAGAAG GAGTTCCTCA TGTGCAAGTT CCAGGAGGCC
AGGAAACTGG TGGAGAGACT CGGCCTGGAG AAGCTCGATC TGAAGAGGCA GAAGGAGCAG
GCTCTGCGGG AGGTGGAGCA CCTGAAGAGA TGCCAGCAGA TGGCTGAGGA CAAGGCCTCT
GTGAAAGCCC AGGTGACGTC CTTGCTCGGG GAGCTGCAGG AGAGCCAGAG TCGCTTGGAG
GCTGCCACTA AGGAATGCCA GGCTCTGGAG GGTCGGGCCC GGGCGGCCAG CGAGCAGGCG
CGGCAGCTGG AGAGTGAGCG CGAGGCGCTG CAGCAGCAGC ACAGCGTGCA GGTGGACCAG
CTGCGCATGC AGGGCCAGAG CGTGGAGGCC GCGCTCCGCA TGGAGCGCCA GGCCGCCTCG
GAGGAGAAGA GGAAGCTGGC CCAGTTGCAG GTGGCCTATC ACCAGCTCTT CCAAGAATAC
GACAACCACA TCAAGAGCAG CGTGGTGGGC AGTGAGCGGA AGCGAGGAAT GCAGCTGGAA
GATCTCAAAC AGCAGCTCCA GCAGGCCGAG GAGGCCCTGG TGGCCAAACA GGAGGTGATC
GATAAGCTGA AGGAGGAGGC CGAGCAGCAC AAGATTGTGA TGGAGACCGT TCCGGTGCTG
AAGGCCCAGG CGGATATCTA CAAGGCGGAC TTCCAGGCTG AGAGGCAGGC CCGGGAGAAG
CTGGCCGAGA AGAAGGAGCT CCTGCAGGAG CAGCTGGAGC AGCTGCAGAG GGAGTACAGC
AAACTGAAGG CCAGCTGTCA GGAGTCGGCC AGGATCGAGG ACATGAGGAA GCGGCATGTC
GAGGTCTCCC AGGCCCCCTT GCCCCCCGCC CCTGCCTACC TCTCCTCTCC CCTGGCCCTG
CCCAGCCAGA GGAGGAGCCC CCCCGAGGAG CCACCTGACT TCTGCTGTCC CAAGTGCCAG
TATCAGGCCC CTGATATGGA CACCCTGCAG ATACATGTCA TGGAGTGCAT TGAGTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu61912
Accession Version XM_011531207.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 813bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product NF-kappa-B essential modulator isoform X7
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_011681.17) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
ATGGCCCTTG TGATCCAGGT GGGGAAACTA AGGCCCAGAG AAGTGAGGAC CCCGCAGACT 
ATCAATCCCA GTCTCTTCCC CTCACTCCCT GTGAAGCTCT CCAGCATCAT CGAGGTCCCA
TCAGGTGGGG AAAGATGCTG TTCCAGGCGC ACACTAGTCT ACAAGGCCAG AGCTTTCTGG
AAGGGGGCAC CCTTGCCCTG TTGGATGAAT AGGCACCTCT GGAAGAGCCA ACTGTGTGAG
ATGGTGCAGC CCAGTGGTGG CCCGGCAGCA GATCAGGACG TACTGGGCGA AGAGTCTCCT
CTGGGGAAGC CAGCCATGCT GCACCTGCCT TCAGAACAGG GCGCTCCTGA GACCCTCCAG
CGCTGCCTGG AGGAGAATCA AGAGCTCCGA GATGCCATCC GGCAGAGCAA CCAGATTCTG
CGGGAGCGCT GCGAGGAGCT TCTGCATTTC CAAGCCAGCC AGAGGGAGGA GAAGGAGTTC
CTCATGTGCA AGTTCCAGGA GGCCAGGAAA CTGGTGGAGA GACTCGGCCT GGAGAAGCTC
GATCTGAAGA GGCAGAAGGA GCAGGCTCTG CGGGAGGTGG AGCACCTGAA GAGATGCCAG
CAGCAGATGG CTGAGGACAA GGCCTCTGTG AAAGCCCAGG TGACGTCCTT GCTCGGGGAG
CTGCAGGAGA GCCAGAGTCG CTTGGAGGCT GCCACTAAGG AATGCCAGGC TCTGGAGGGT
CGACAGATGG ATCAGCTGCC AGGGGGGCCC CAGCCATCCC AGCACAGTCT CCTTGCCATC
TGTACTTGGT CACCTGCTGG GCCCCTGCAT TGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeqXP_011529509.1
CDS27..839
Misc Feature(1)360..563(+)
Translation
Position Chain Variation Link
237 237 a, c dbSNP:57174646
399 399 a, g dbSNP:148695964
414 414 c, t dbSNP:137853323
495 495 -, gag dbSNP:386134238
567 567 a, g dbSNP:179363896
597 597 c, t dbSNP:179363895
688 688 g, t dbSNP:137853328
700 700 a, c dbSNP:386134240
747 747 c, g dbSNP:179363866

Target ORF information:

RefSeq Version XM_011531207
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma (IKBKG), transcript variant X8, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011531207

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
ATGGCCCTTG TGATCCAGGT GGGGAAACTA AGGCCCAGAG AAGTGAGGAC CCCGCAGACT 
ATCAATCCCA GTCTCTTCCC CTCACTCCCT GTGAAGCTCT CCAGCATCAT CGAGGTCCCA
TCAGGTGGGG AAAGATGCTG TTCCAGGCGC ACACTAGTCT ACAAGGCCAG AGCTTTCTGG
AAGGGGGCAC CCTTGCCCTG TTGGATGAAT AGGCACCTCT GGAAGAGCCA ACTGTGTGAG
ATGGTGCAGC CCAGTGGTGG CCCGGCAGCA GATCAGGACG TACTGGGCGA AGAGTCTCCT
CTGGGGAAGC CAGCCATGCT GCACCTGCCT TCAGAACAGG GCGCTCCTGA GACCCTCCAG
CGCTGCCTGG AGGAGAATCA AGAGCTCCGA GATGCCATCC GGCAGAGCAA CCAGATTCTG
CGGGAGCGCT GCGAGGAGCT TCTGCATTTC CAAGCCAGCC AGAGGGAGGA GAAGGAGTTC
CTCATGTGCA AGTTCCAGGA GGCCAGGAAA CTGGTGGAGA GACTCGGCCT GGAGAAGCTC
GATCTGAAGA GGCAGAAGGA GCAGGCTCTG CGGGAGGTGG AGCACCTGAA GAGATGCCAG
CAGCAGATGG CTGAGGACAA GGCCTCTGTG AAAGCCCAGG TGACGTCCTT GCTCGGGGAG
CTGCAGGAGA GCCAGAGTCG CTTGGAGGCT GCCACTAAGG AATGCCAGGC TCTGGAGGGT
CGACAGATGG ATCAGCTGCC AGGGGGGCCC CAGCCATCCC AGCACAGTCT CCTTGCCATC
TGTACTTGGT CACCTGCTGG GCCCCTGCAT TGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu27518
Accession Version NM_001099857.2 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1260bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product NF-kappa-B essential modulator isoform a
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK308366.1, BC050612.2, BC000299.2 and AF062089.1. On Sep 17, 2013 this sequence version replaced gi:153792132. Summary: This gene encodes the regulatory subunit of the inhibitor of kappaB kinase (IKK) complex, which activates NF-kappaB resulting in activation of genes involved in inflammation, immunity, cell survival, and other pathways. Mutations in this gene result in incontinentia pigmenti, hypohidrotic ectodermal dysplasia, and several other types of immunodeficiencies. Multiple transcript variants encoding different isoforms have been found for this gene. A pseudogene highly similar to this locus is located in an adjacent region of the X chromosome. [provided by RefSeq, Aug 2011]. Transcript Variant: This variant (1) represents the longest transcript and encodes isoform a. Variants 1 and 3 encode the same isoform. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF062089.1, BC050612.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
ATGAATAGGC ACCTCTGGAA GAGCCAACTG TGTGAGATGG TGCAGCCCAG TGGTGGCCCG 
GCAGCAGATC AGGACGTACT GGGCGAAGAG TCTCCTCTGG GGAAGCCAGC CATGCTGCAC
CTGCCTTCAG AACAGGGCGC TCCTGAGACC CTCCAGCGCT GCCTGGAGGA GAATCAAGAG
CTCCGAGATG CCATCCGGCA GAGCAACCAG ATTCTGCGGG AGCGCTGCGA GGAGCTTCTG
CATTTCCAAG CCAGCCAGAG GGAGGAGAAG GAGTTCCTCA TGTGCAAGTT CCAGGAGGCC
AGGAAACTGG TGGAGAGACT CGGCCTGGAG AAGCTCGATC TGAAGAGGCA GAAGGAGCAG
GCTCTGCGGG AGGTGGAGCA CCTGAAGAGA TGCCAGCAGC AGATGGCTGA GGACAAGGCC
TCTGTGAAAG CCCAGGTGAC GTCCTTGCTC GGGGAGCTGC AGGAGAGCCA GAGTCGCTTG
GAGGCTGCCA CTAAGGAATG CCAGGCTCTG GAGGGTCGGG CCCGGGCGGC CAGCGAGCAG
GCGCGGCAGC TGGAGAGTGA GCGCGAGGCG CTGCAGCAGC AGCACAGCGT GCAGGTGGAC
CAGCTGCGCA TGCAGGGCCA GAGCGTGGAG GCCGCGCTCC GCATGGAGCG CCAGGCCGCC
TCGGAGGAGA AGAGGAAGCT GGCCCAGTTG CAGGTGGCCT ATCACCAGCT CTTCCAAGAA
TACGACAACC ACATCAAGAG CAGCGTGGTG GGCAGTGAGC GGAAGCGAGG AATGCAGCTG
GAAGATCTCA AACAGCAGCT CCAGCAGGCC GAGGAGGCCC TGGTGGCCAA ACAGGAGGTG
ATCGATAAGC TGAAGGAGGA GGCCGAGCAG CACAAGATTG TGATGGAGAC CGTTCCGGTG
CTGAAGGCCC AGGCGGATAT CTACAAGGCG GACTTCCAGG CTGAGAGGCA GGCCCGGGAG
AAGCTGGCCG AGAAGAAGGA GCTCCTGCAG GAGCAGCTGG AGCAGCTGCA GAGGGAGTAC
AGCAAACTGA AGGCCAGCTG TCAGGAGTCG GCCAGGATCG AGGACATGAG GAAGCGGCAT
GTCGAGGTCT CCCAGGCCCC CTTGCCCCCC GCCCCTGCCT ACCTCTCCTC TCCCCTGGCC
CTGCCCAGCC AGAGGAGGAG CCCCCCCGAG GAGCCACCTG ACTTCTGCTG TCCCAAGTGC
CAGTATCAGG CCCCTGATAT GGACACCCTG CAGATACATG TCATGGAGTG CATTGAGTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeqNP_001093327.1
CDS415..1674
Misc Feature(1)394..396(+)
Misc Feature(2)505..507(+)
Misc Feature(3)541..543(+)
Misc Feature(4)544..747(+)
Misc Feature(5)544..747(+)
Misc Feature(6)616..618(+)
Misc Feature(7)667..669(+)
Misc Feature(8)862..1185(+)
Misc Feature(9)1138..1464(+)
Misc Feature(10)1150..1509(+)
Misc Feature(11)1165..1671(+)
Misc Feature(12)1186..1446(+)
Misc Feature(13)1189..1434(+)
Misc Feature(14)1300..1395(+)
Misc Feature(15)1378..1443(+)
Misc Feature(16)1540..1542(+)
Misc Feature(17)1558..1671(+)
Misc Feature(18)1573..1575(+)
Exon (1)1..399
Gene:IKBKG
Gene Synonym:
Exon (2)400..601
Gene:IKBKG
Gene Synonym:
Exon (3)602..813
Gene:IKBKG
Gene Synonym:
Exon (4)814..932
Gene:IKBKG
Gene Synonym:
Exon (5)933..1085
Gene:IKBKG
Gene Synonym:
Exon (6)1086..1182
Gene:IKBKG
Gene Synonym:
Exon (7)1183..1326
Gene:IKBKG
Gene Synonym:
Exon (8)1327..1469
Gene:IKBKG
Gene Synonym:
Exon (9)1470..1531
Gene:IKBKG
Gene Synonym:
Exon (10)1532..2259
Gene:IKBKG
Gene Synonym:
Translation
Position Chain Variation Link
224 224 c, t dbSNP:111827785
421 421 a, c dbSNP:57174646
583 583 a, g dbSNP:148695964
598 598 c, t dbSNP:137853323
679 679 -, gag dbSNP:386134238
751 751 a, g dbSNP:179363896
781 781 c, t dbSNP:179363895
872 872 g, t dbSNP:137853328
884 884 a, c dbSNP:386134240
931 931 c, g dbSNP:179363866
938 938 c, g dbSNP:179363868
1094 1094 c, t dbSNP:179363869
1277 1277 c, g dbSNP:137853330
1345 1345 a, g dbSNP:179363867
1358 1358 a, c dbSNP:137853331
1370 1370 a, g dbSNP:137853332
1381 1381 c, g dbSNP:179363865
1585 1585 g, t dbSNP:137853324
1621 1621 c, t dbSNP:137853329
1631 1631 a, t dbSNP:137853327
1633 1633 a, g dbSNP:137853322
1663 1663 c, t dbSNP:137853325
1664 1664 a, g, t dbSNP:137853326
1673 1673 a, g dbSNP:137853321

Target ORF information:

RefSeq Version NM_001099857
Organism Homo sapiens (human)
Definition Homo sapiens inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma (IKBKG), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001099857

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
ATGAATAGGC ACCTCTGGAA GAGCCAACTG TGTGAGATGG TGCAGCCCAG TGGTGGCCCG 
GCAGCAGATC AGGACGTACT GGGCGAAGAG TCTCCTCTGG GGAAGCCAGC CATGCTGCAC
CTGCCTTCAG AACAGGGCGC TCCTGAGACC CTCCAGCGCT GCCTGGAGGA GAATCAAGAG
CTCCGAGATG CCATCCGGCA GAGCAACCAG ATTCTGCGGG AGCGCTGCGA GGAGCTTCTG
CATTTCCAAG CCAGCCAGAG GGAGGAGAAG GAGTTCCTCA TGTGCAAGTT CCAGGAGGCC
AGGAAACTGG TGGAGAGACT CGGCCTGGAG AAGCTCGATC TGAAGAGGCA GAAGGAGCAG
GCTCTGCGGG AGGTGGAGCA CCTGAAGAGA TGCCAGCAGC AGATGGCTGA GGACAAGGCC
TCTGTGAAAG CCCAGGTGAC GTCCTTGCTC GGGGAGCTGC AGGAGAGCCA GAGTCGCTTG
GAGGCTGCCA CTAAGGAATG CCAGGCTCTG GAGGGTCGGG CCCGGGCGGC CAGCGAGCAG
GCGCGGCAGC TGGAGAGTGA GCGCGAGGCG CTGCAGCAGC AGCACAGCGT GCAGGTGGAC
CAGCTGCGCA TGCAGGGCCA GAGCGTGGAG GCCGCGCTCC GCATGGAGCG CCAGGCCGCC
TCGGAGGAGA AGAGGAAGCT GGCCCAGTTG CAGGTGGCCT ATCACCAGCT CTTCCAAGAA
TACGACAACC ACATCAAGAG CAGCGTGGTG GGCAGTGAGC GGAAGCGAGG AATGCAGCTG
GAAGATCTCA AACAGCAGCT CCAGCAGGCC GAGGAGGCCC TGGTGGCCAA ACAGGAGGTG
ATCGATAAGC TGAAGGAGGA GGCCGAGCAG CACAAGATTG TGATGGAGAC CGTTCCGGTG
CTGAAGGCCC AGGCGGATAT CTACAAGGCG GACTTCCAGG CTGAGAGGCA GGCCCGGGAG
AAGCTGGCCG AGAAGAAGGA GCTCCTGCAG GAGCAGCTGG AGCAGCTGCA GAGGGAGTAC
AGCAAACTGA AGGCCAGCTG TCAGGAGTCG GCCAGGATCG AGGACATGAG GAAGCGGCAT
GTCGAGGTCT CCCAGGCCCC CTTGCCCCCC GCCCCTGCCT ACCTCTCCTC TCCCCTGGCC
CTGCCCAGCC AGAGGAGGAG CCCCCCCGAG GAGCCACCTG ACTTCTGCTG TCCCAAGTGC
CAGTATCAGG CCCCTGATAT GGACACCCTG CAGATACATG TCATGGAGTG CATTGAGTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu16932
Accession Version NM_001099856.3 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1464bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product NF-kappa-B essential modulator isoform b
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AY114157.1, BC000299.2 and AF062089.1. On Sep 17, 2013 this sequence version replaced gi:223671869. Summary: This gene encodes the regulatory subunit of the inhibitor of kappaB kinase (IKK) complex, which activates NF-kappaB resulting in activation of genes involved in inflammation, immunity, cell survival, and other pathways. Mutations in this gene result in incontinentia pigmenti, hypohidrotic ectodermal dysplasia, and several other types of immunodeficiencies. Multiple transcript variants encoding different isoforms have been found for this gene. A pseudogene highly similar to this locus is located in an adjacent region of the X chromosome. [provided by RefSeq, Aug 2011]. Transcript Variant: This variant (2) uses an alternate promoter and initiates translation from an alternate in-frame upstream start codon compared to variant 1. The resulting isoform (b) has a longer N-terminus compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY114157.1, BC012114.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2142670, SAMEA2142680 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
ATGGCCCTTG TGATCCAGGT GGGGAAACTA AGGCCCAGAG AAGTGAGGAC CCCGCAGACT 
ATCAATCCCA GTCTCTTCCC CTCACTCCCT GTGAAGCTCT CCAGCATCAT CGAGGTCCCA
TCAGGTGGGG AAAGATGCTG TTCCAGGCGC ACACTAGTCT ACAAGGCCAG AGCTTTCTGG
AAGGGGGCAC CCTTGCCCTG TTGGATGAAT AGGCACCTCT GGAAGAGCCA ACTGTGTGAG
ATGGTGCAGC CCAGTGGTGG CCCGGCAGCA GATCAGGACG TACTGGGCGA AGAGTCTCCT
CTGGGGAAGC CAGCCATGCT GCACCTGCCT TCAGAACAGG GCGCTCCTGA GACCCTCCAG
CGCTGCCTGG AGGAGAATCA AGAGCTCCGA GATGCCATCC GGCAGAGCAA CCAGATTCTG
CGGGAGCGCT GCGAGGAGCT TCTGCATTTC CAAGCCAGCC AGAGGGAGGA GAAGGAGTTC
CTCATGTGCA AGTTCCAGGA GGCCAGGAAA CTGGTGGAGA GACTCGGCCT GGAGAAGCTC
GATCTGAAGA GGCAGAAGGA GCAGGCTCTG CGGGAGGTGG AGCACCTGAA GAGATGCCAG
CAGCAGATGG CTGAGGACAA GGCCTCTGTG AAAGCCCAGG TGACGTCCTT GCTCGGGGAG
CTGCAGGAGA GCCAGAGTCG CTTGGAGGCT GCCACTAAGG AATGCCAGGC TCTGGAGGGT
CGGGCCCGGG CGGCCAGCGA GCAGGCGCGG CAGCTGGAGA GTGAGCGCGA GGCGCTGCAG
CAGCAGCACA GCGTGCAGGT GGACCAGCTG CGCATGCAGG GCCAGAGCGT GGAGGCCGCG
CTCCGCATGG AGCGCCAGGC CGCCTCGGAG GAGAAGAGGA AGCTGGCCCA GTTGCAGGTG
GCCTATCACC AGCTCTTCCA AGAATACGAC AACCACATCA AGAGCAGCGT GGTGGGCAGT
GAGCGGAAGC GAGGAATGCA GCTGGAAGAT CTCAAACAGC AGCTCCAGCA GGCCGAGGAG
GCCCTGGTGG CCAAACAGGA GGTGATCGAT AAGCTGAAGG AGGAGGCCGA GCAGCACAAG
ATTGTGATGG AGACCGTTCC GGTGCTGAAG GCCCAGGCGG ATATCTACAA GGCGGACTTC
CAGGCTGAGA GGCAGGCCCG GGAGAAGCTG GCCGAGAAGA AGGAGCTCCT GCAGGAGCAG
CTGGAGCAGC TGCAGAGGGA GTACAGCAAA CTGAAGGCCA GCTGTCAGGA GTCGGCCAGG
ATCGAGGACA TGAGGAAGCG GCATGTCGAG GTCTCCCAGG CCCCCTTGCC CCCCGCCCCT
GCCTACCTCT CCTCTCCCCT GGCCCTGCCC AGCCAGAGGA GGAGCCCCCC CGAGGAGCCA
CCTGACTTCT GCTGTCCCAA GTGCCAGTAT CAGGCCCCTG ATATGGACAC CCTGCAGATA
CATGTCATGG AGTGCATTGA GTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeqNP_001093326.2
CDS21..1484
Misc Feature(1)3..5(+)
Misc Feature(2)354..557(+)
Misc Feature(3)996..1256(+)
Misc Feature(4)999..1244(+)
Misc Feature(5)1110..1205(+)
Exon (1)1..209
Gene:IKBKG
Gene Synonym:
Exon (2)210..411
Gene:IKBKG
Gene Synonym:
Exon (3)412..623
Gene:IKBKG
Gene Synonym:
Exon (4)624..742
Gene:IKBKG
Gene Synonym:
Exon (5)743..895
Gene:IKBKG
Gene Synonym:
Exon (6)896..992
Gene:IKBKG
Gene Synonym:
Exon (7)993..1136
Gene:IKBKG
Gene Synonym:
Exon (8)1137..1279
Gene:IKBKG
Gene Synonym:
Exon (9)1280..1341
Gene:IKBKG
Gene Synonym:
Exon (10)1342..2069
Gene:IKBKG
Gene Synonym:
Translation
Position Chain Variation Link
231 231 a, c dbSNP:57174646
393 393 a, g dbSNP:148695964
408 408 c, t dbSNP:137853323
489 489 -, gag dbSNP:386134238
561 561 a, g dbSNP:179363896
591 591 c, t dbSNP:179363895
682 682 g, t dbSNP:137853328
694 694 a, c dbSNP:386134240
741 741 c, g dbSNP:179363866
748 748 c, g dbSNP:179363868
904 904 c, t dbSNP:179363869
1087 1087 c, g dbSNP:137853330
1155 1155 a, g dbSNP:179363867
1168 1168 a, c dbSNP:137853331
1180 1180 a, g dbSNP:137853332
1191 1191 c, g dbSNP:179363865
1395 1395 g, t dbSNP:137853324
1431 1431 c, t dbSNP:137853329
1441 1441 a, t dbSNP:137853327
1443 1443 a, g dbSNP:137853322
1473 1473 c, t dbSNP:137853325
1474 1474 a, g, t dbSNP:137853326
1483 1483 a, g dbSNP:137853321

Target ORF information:

RefSeq Version NM_001099856
Organism Homo sapiens (human)
Definition Homo sapiens inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma (IKBKG), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001099856

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
ATGGCCCTTG TGATCCAGGT GGGGAAACTA AGGCCCAGAG AAGTGAGGAC CCCGCAGACT 
ATCAATCCCA GTCTCTTCCC CTCACTCCCT GTGAAGCTCT CCAGCATCAT CGAGGTCCCA
TCAGGTGGGG AAAGATGCTG TTCCAGGCGC ACACTAGTCT ACAAGGCCAG AGCTTTCTGG
AAGGGGGCAC CCTTGCCCTG TTGGATGAAT AGGCACCTCT GGAAGAGCCA ACTGTGTGAG
ATGGTGCAGC CCAGTGGTGG CCCGGCAGCA GATCAGGACG TACTGGGCGA AGAGTCTCCT
CTGGGGAAGC CAGCCATGCT GCACCTGCCT TCAGAACAGG GCGCTCCTGA GACCCTCCAG
CGCTGCCTGG AGGAGAATCA AGAGCTCCGA GATGCCATCC GGCAGAGCAA CCAGATTCTG
CGGGAGCGCT GCGAGGAGCT TCTGCATTTC CAAGCCAGCC AGAGGGAGGA GAAGGAGTTC
CTCATGTGCA AGTTCCAGGA GGCCAGGAAA CTGGTGGAGA GACTCGGCCT GGAGAAGCTC
GATCTGAAGA GGCAGAAGGA GCAGGCTCTG CGGGAGGTGG AGCACCTGAA GAGATGCCAG
CAGCAGATGG CTGAGGACAA GGCCTCTGTG AAAGCCCAGG TGACGTCCTT GCTCGGGGAG
CTGCAGGAGA GCCAGAGTCG CTTGGAGGCT GCCACTAAGG AATGCCAGGC TCTGGAGGGT
CGGGCCCGGG CGGCCAGCGA GCAGGCGCGG CAGCTGGAGA GTGAGCGCGA GGCGCTGCAG
CAGCAGCACA GCGTGCAGGT GGACCAGCTG CGCATGCAGG GCCAGAGCGT GGAGGCCGCG
CTCCGCATGG AGCGCCAGGC CGCCTCGGAG GAGAAGAGGA AGCTGGCCCA GTTGCAGGTG
GCCTATCACC AGCTCTTCCA AGAATACGAC AACCACATCA AGAGCAGCGT GGTGGGCAGT
GAGCGGAAGC GAGGAATGCA GCTGGAAGAT CTCAAACAGC AGCTCCAGCA GGCCGAGGAG
GCCCTGGTGG CCAAACAGGA GGTGATCGAT AAGCTGAAGG AGGAGGCCGA GCAGCACAAG
ATTGTGATGG AGACCGTTCC GGTGCTGAAG GCCCAGGCGG ATATCTACAA GGCGGACTTC
CAGGCTGAGA GGCAGGCCCG GGAGAAGCTG GCCGAGAAGA AGGAGCTCCT GCAGGAGCAG
CTGGAGCAGC TGCAGAGGGA GTACAGCAAA CTGAAGGCCA GCTGTCAGGA GTCGGCCAGG
ATCGAGGACA TGAGGAAGCG GCATGTCGAG GTCTCCCAGG CCCCCTTGCC CCCCGCCCCT
GCCTACCTCT CCTCTCCCCT GGCCCTGCCC AGCCAGAGGA GGAGCCCCCC CGAGGAGCCA
CCTGACTTCT GCTGTCCCAA GTGCCAGTAT CAGGCCCCTG ATATGGACAC CCTGCAGATA
CATGTCATGG AGTGCATTGA GTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu27518
Accession Version NM_003639.4 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1260bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product NF-kappa-B essential modulator isoform a
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF261086.1, BC000299.2 and AF062089.1. On Sep 17, 2013 this sequence version replaced gi:142381344. Summary: This gene encodes the regulatory subunit of the inhibitor of kappaB kinase (IKK) complex, which activates NF-kappaB resulting in activation of genes involved in inflammation, immunity, cell survival, and other pathways. Mutations in this gene result in incontinentia pigmenti, hypohidrotic ectodermal dysplasia, and several other types of immunodeficiencies. Multiple transcript variants encoding different isoforms have been found for this gene. A pseudogene highly similar to this locus is located in an adjacent region of the X chromosome. [provided by RefSeq, Aug 2011]. Transcript Variant: This variant (3) contains an alternate 5' non-coding exon compared to variant 1. Variants 1 and 3 both encode the same isoform (a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF261086.1, AF091453.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
ATGAATAGGC ACCTCTGGAA GAGCCAACTG TGTGAGATGG TGCAGCCCAG TGGTGGCCCG 
GCAGCAGATC AGGACGTACT GGGCGAAGAG TCTCCTCTGG GGAAGCCAGC CATGCTGCAC
CTGCCTTCAG AACAGGGCGC TCCTGAGACC CTCCAGCGCT GCCTGGAGGA GAATCAAGAG
CTCCGAGATG CCATCCGGCA GAGCAACCAG ATTCTGCGGG AGCGCTGCGA GGAGCTTCTG
CATTTCCAAG CCAGCCAGAG GGAGGAGAAG GAGTTCCTCA TGTGCAAGTT CCAGGAGGCC
AGGAAACTGG TGGAGAGACT CGGCCTGGAG AAGCTCGATC TGAAGAGGCA GAAGGAGCAG
GCTCTGCGGG AGGTGGAGCA CCTGAAGAGA TGCCAGCAGC AGATGGCTGA GGACAAGGCC
TCTGTGAAAG CCCAGGTGAC GTCCTTGCTC GGGGAGCTGC AGGAGAGCCA GAGTCGCTTG
GAGGCTGCCA CTAAGGAATG CCAGGCTCTG GAGGGTCGGG CCCGGGCGGC CAGCGAGCAG
GCGCGGCAGC TGGAGAGTGA GCGCGAGGCG CTGCAGCAGC AGCACAGCGT GCAGGTGGAC
CAGCTGCGCA TGCAGGGCCA GAGCGTGGAG GCCGCGCTCC GCATGGAGCG CCAGGCCGCC
TCGGAGGAGA AGAGGAAGCT GGCCCAGTTG CAGGTGGCCT ATCACCAGCT CTTCCAAGAA
TACGACAACC ACATCAAGAG CAGCGTGGTG GGCAGTGAGC GGAAGCGAGG AATGCAGCTG
GAAGATCTCA AACAGCAGCT CCAGCAGGCC GAGGAGGCCC TGGTGGCCAA ACAGGAGGTG
ATCGATAAGC TGAAGGAGGA GGCCGAGCAG CACAAGATTG TGATGGAGAC CGTTCCGGTG
CTGAAGGCCC AGGCGGATAT CTACAAGGCG GACTTCCAGG CTGAGAGGCA GGCCCGGGAG
AAGCTGGCCG AGAAGAAGGA GCTCCTGCAG GAGCAGCTGG AGCAGCTGCA GAGGGAGTAC
AGCAAACTGA AGGCCAGCTG TCAGGAGTCG GCCAGGATCG AGGACATGAG GAAGCGGCAT
GTCGAGGTCT CCCAGGCCCC CTTGCCCCCC GCCCCTGCCT ACCTCTCCTC TCCCCTGGCC
CTGCCCAGCC AGAGGAGGAG CCCCCCCGAG GAGCCACCTG ACTTCTGCTG TCCCAAGTGC
CAGTATCAGG CCCCTGATAT GGACACCCTG CAGATACATG TCATGGAGTG CATTGAGTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeqNP_003630.1
CDS259..1518
Misc Feature(1)241..243(+)
Misc Feature(2)349..351(+)
Misc Feature(3)349..351(+)
Misc Feature(4)385..387(+)
Misc Feature(5)385..387(+)
Misc Feature(6)388..591(+)
Misc Feature(7)388..591(+)
Misc Feature(8)460..462(+)
Misc Feature(9)511..513(+)
Misc Feature(10)706..1029(+)
Misc Feature(11)982..1308(+)
Misc Feature(12)994..1353(+)
Misc Feature(13)1009..1515(+)
Misc Feature(14)1030..1290(+)
Misc Feature(15)1033..1278(+)
Misc Feature(16)1144..1239(+)
Misc Feature(17)1222..1287(+)
Misc Feature(18)1384..1386(+)
Misc Feature(19)1384..1386(+)
Misc Feature(20)1402..1515(+)
Misc Feature(21)1417..1419(+)
Misc Feature(22)1453..1455(+)
Exon (1)1..243
Gene:IKBKG
Gene Synonym:
Exon (2)244..445
Gene:IKBKG
Gene Synonym:
Exon (3)446..657
Gene:IKBKG
Gene Synonym:
Exon (4)658..776
Gene:IKBKG
Gene Synonym:
Exon (5)777..929
Gene:IKBKG
Gene Synonym:
Exon (6)930..1026
Gene:IKBKG
Gene Synonym:
Exon (7)1027..1170
Gene:IKBKG
Gene Synonym:
Exon (8)1171..1313
Gene:IKBKG
Gene Synonym:
Exon (9)1314..1375
Gene:IKBKG
Gene Synonym:
Exon (10)1376..2103
Gene:IKBKG
Gene Synonym:
Translation
Position Chain Variation Link
94 94 c, g dbSNP:56262786
116 116 g, t dbSNP:73641104
265 265 a, c dbSNP:57174646
427 427 a, g dbSNP:148695964
442 442 c, t dbSNP:137853323
523 523 -, gag dbSNP:386134238
595 595 a, g dbSNP:179363896
625 625 c, t dbSNP:179363895
716 716 g, t dbSNP:137853328
728 728 a, c dbSNP:386134240
775 775 c, g dbSNP:179363866
782 782 c, g dbSNP:179363868
938 938 c, t dbSNP:179363869
1121 1121 c, g dbSNP:137853330
1189 1189 a, g dbSNP:179363867
1202 1202 a, c dbSNP:137853331
1214 1214 a, g dbSNP:137853332
1225 1225 c, g dbSNP:179363865
1429 1429 g, t dbSNP:137853324
1465 1465 c, t dbSNP:137853329
1475 1475 a, t dbSNP:137853327
1477 1477 a, g dbSNP:137853322
1507 1507 c, t dbSNP:137853325
1508 1508 a, g, t dbSNP:137853326
1517 1517 a, g dbSNP:137853321

Target ORF information:

RefSeq Version NM_003639
Organism Homo sapiens (human)
Definition Homo sapiens inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma (IKBKG), transcript variant 3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_003639

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
ATGAATAGGC ACCTCTGGAA GAGCCAACTG TGTGAGATGG TGCAGCCCAG TGGTGGCCCG 
GCAGCAGATC AGGACGTACT GGGCGAAGAG TCTCCTCTGG GGAAGCCAGC CATGCTGCAC
CTGCCTTCAG AACAGGGCGC TCCTGAGACC CTCCAGCGCT GCCTGGAGGA GAATCAAGAG
CTCCGAGATG CCATCCGGCA GAGCAACCAG ATTCTGCGGG AGCGCTGCGA GGAGCTTCTG
CATTTCCAAG CCAGCCAGAG GGAGGAGAAG GAGTTCCTCA TGTGCAAGTT CCAGGAGGCC
AGGAAACTGG TGGAGAGACT CGGCCTGGAG AAGCTCGATC TGAAGAGGCA GAAGGAGCAG
GCTCTGCGGG AGGTGGAGCA CCTGAAGAGA TGCCAGCAGC AGATGGCTGA GGACAAGGCC
TCTGTGAAAG CCCAGGTGAC GTCCTTGCTC GGGGAGCTGC AGGAGAGCCA GAGTCGCTTG
GAGGCTGCCA CTAAGGAATG CCAGGCTCTG GAGGGTCGGG CCCGGGCGGC CAGCGAGCAG
GCGCGGCAGC TGGAGAGTGA GCGCGAGGCG CTGCAGCAGC AGCACAGCGT GCAGGTGGAC
CAGCTGCGCA TGCAGGGCCA GAGCGTGGAG GCCGCGCTCC GCATGGAGCG CCAGGCCGCC
TCGGAGGAGA AGAGGAAGCT GGCCCAGTTG CAGGTGGCCT ATCACCAGCT CTTCCAAGAA
TACGACAACC ACATCAAGAG CAGCGTGGTG GGCAGTGAGC GGAAGCGAGG AATGCAGCTG
GAAGATCTCA AACAGCAGCT CCAGCAGGCC GAGGAGGCCC TGGTGGCCAA ACAGGAGGTG
ATCGATAAGC TGAAGGAGGA GGCCGAGCAG CACAAGATTG TGATGGAGAC CGTTCCGGTG
CTGAAGGCCC AGGCGGATAT CTACAAGGCG GACTTCCAGG CTGAGAGGCA GGCCCGGGAG
AAGCTGGCCG AGAAGAAGGA GCTCCTGCAG GAGCAGCTGG AGCAGCTGCA GAGGGAGTAC
AGCAAACTGA AGGCCAGCTG TCAGGAGTCG GCCAGGATCG AGGACATGAG GAAGCGGCAT
GTCGAGGTCT CCCAGGCCCC CTTGCCCCCC GCCCCTGCCT ACCTCTCCTC TCCCCTGGCC
CTGCCCAGCC AGAGGAGGAG CCCCCCCGAG GAGCCACCTG ACTTCTGCTG TCCCAAGTGC
CAGTATCAGG CCCCTGATAT GGACACCCTG CAGATACATG TCATGGAGTG CATTGAGTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu27490
Accession Version NM_001145255.2 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 963bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product NF-kappa-B essential modulator isoform c
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK308366.1, AK000593.1, BC000299.2 and AF062089.1. On Sep 17, 2013 this sequence version replaced gi:223671871. Summary: This gene encodes the regulatory subunit of the inhibitor of kappaB kinase (IKK) complex, which activates NF-kappaB resulting in activation of genes involved in inflammation, immunity, cell survival, and other pathways. Mutations in this gene result in incontinentia pigmenti, hypohidrotic ectodermal dysplasia, and several other types of immunodeficiencies. Multiple transcript variants encoding different isoforms have been found for this gene. A pseudogene highly similar to this locus is located in an adjacent region of the X chromosome. [provided by RefSeq, Aug 2011]. Transcript Variant: This variant (4) lacks two in-frame exons in the central coding region compared to variant 1. The resulting isoform (c) lacks two internal protein segments compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK000593.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2154529 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
ATGAATAGGC ACCTCTGGAA GAGCCAACTG TGTGAGATGG TGCAGCCCAG TGGTGGCCCG 
GCAGCAGATC AGGACGTACT GGGCGAAGAG TCTCCTCTGG GGAAGCCAGC CATGCTGCAC
CTGCCTTCAG AACAGGGCGC TCCTGAGACC CTCCAGCGCT GCCTGGAGGA GAATCAAGAG
CTCCGAGATG CCATCCGGCA GAGCAACCAG ATTCTGCGGG AGCGCTGCGA GGAGCTTCTG
CATTTCCAAG CCAGCCAGAG GGAGGAGAAG GAGTTCCTCA TGTGCAAGTT CCAGGAGGCC
AGGAAACTGG TGGAGAGACT CGGCCTGGAG AAGCTCGATC TGAAGAGGCA GAAGGAGCAG
GCTCTGCGGG AGGTGGAGCA CCTGAAGAGA TGCCAGCAGC AGATGGCTGA GGACAAGGCC
TCTGTGAAAG CCCAGGTGAC GTCCTTGCTC GGGGAGCTGC AGGAGAGCCA GAGTCGCTTG
GAGGCTGCCA CTAAGGAATG CCAGGCTCTG GAGGGTCGGA GGAAGCTGGC CCAGTTGCAG
GTGGCCTATC ACCAGCTCTT CCAAGAATAC GACAACCACA TCAAGAGCAG CGTGGTGGGC
AGTGAGCGGA AGCGAGCGGA TATCTACAAG GCGGACTTCC AGGCTGAGAG GCAGGCCCGG
GAGAAGCTGG CCGAGAAGAA GGAGCTCCTG CAGGAGCAGC TGGAGCAGCT GCAGAGGGAG
TACAGCAAAC TGAAGGCCAG CTGTCAGGAG TCGGCCAGGA TCGAGGACAT GAGGAAGCGG
CATGTCGAGG TCTCCCAGGC CCCCTTGCCC CCCGCCCCTG CCTACCTCTC CTCTCCCCTG
GCCCTGCCCA GCCAGAGGAG GAGCCCCCCC GAGGAGCCAC CTGACTTCTG CTGTCCCAAG
TGCCAGTATC AGGCCCCTGA TATGGACACC CTGCAGATAC ATGTCATGGA GTGCATTGAG
TAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeqNP_001138727.1
CDS415..1377
Misc Feature(1)394..396(+)
Misc Feature(2)544..747(+)
Misc Feature(3)1021..1149(+)
Misc Feature(4)1024..1098(+)
Exon (1)1..399
Gene:IKBKG
Gene Synonym:
Exon (2)400..601
Gene:IKBKG
Gene Synonym:
Exon (3)602..813
Gene:IKBKG
Gene Synonym:
Exon (4)814..932
Gene:IKBKG
Gene Synonym:
Exon (5)933..1029
Gene:IKBKG
Gene Synonym:
Exon (6)1030..1172
Gene:IKBKG
Gene Synonym:
Exon (7)1173..1234
Gene:IKBKG
Gene Synonym:
Exon (8)1235..1962
Gene:IKBKG
Gene Synonym:
Translation
Position Chain Variation Link
224 224 c, t dbSNP:111827785
421 421 a, c dbSNP:57174646
583 583 a, g dbSNP:148695964
598 598 c, t dbSNP:137853323
679 679 -, gag dbSNP:386134238
751 751 a, g dbSNP:179363896
781 781 c, t dbSNP:179363895
872 872 g, t dbSNP:137853328
884 884 a, c dbSNP:386134240
931 931 c, g dbSNP:179363866
941 941 c, t dbSNP:179363869
1048 1048 a, g dbSNP:179363867
1061 1061 a, c dbSNP:137853331
1073 1073 a, g dbSNP:137853332
1084 1084 c, g dbSNP:179363865
1288 1288 g, t dbSNP:137853324
1324 1324 c, t dbSNP:137853329
1334 1334 a, t dbSNP:137853327
1336 1336 a, g dbSNP:137853322
1366 1366 c, t dbSNP:137853325
1367 1367 a, g, t dbSNP:137853326
1376 1376 a, g dbSNP:137853321

Target ORF information:

RefSeq Version NM_001145255
Organism Homo sapiens (human)
Definition Homo sapiens inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma (IKBKG), transcript variant 4, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001145255

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
ATGAATAGGC ACCTCTGGAA GAGCCAACTG TGTGAGATGG TGCAGCCCAG TGGTGGCCCG 
GCAGCAGATC AGGACGTACT GGGCGAAGAG TCTCCTCTGG GGAAGCCAGC CATGCTGCAC
CTGCCTTCAG AACAGGGCGC TCCTGAGACC CTCCAGCGCT GCCTGGAGGA GAATCAAGAG
CTCCGAGATG CCATCCGGCA GAGCAACCAG ATTCTGCGGG AGCGCTGCGA GGAGCTTCTG
CATTTCCAAG CCAGCCAGAG GGAGGAGAAG GAGTTCCTCA TGTGCAAGTT CCAGGAGGCC
AGGAAACTGG TGGAGAGACT CGGCCTGGAG AAGCTCGATC TGAAGAGGCA GAAGGAGCAG
GCTCTGCGGG AGGTGGAGCA CCTGAAGAGA TGCCAGCAGC AGATGGCTGA GGACAAGGCC
TCTGTGAAAG CCCAGGTGAC GTCCTTGCTC GGGGAGCTGC AGGAGAGCCA GAGTCGCTTG
GAGGCTGCCA CTAAGGAATG CCAGGCTCTG GAGGGTCGGA GGAAGCTGGC CCAGTTGCAG
GTGGCCTATC ACCAGCTCTT CCAAGAATAC GACAACCACA TCAAGAGCAG CGTGGTGGGC
AGTGAGCGGA AGCGAGCGGA TATCTACAAG GCGGACTTCC AGGCTGAGAG GCAGGCCCGG
GAGAAGCTGG CCGAGAAGAA GGAGCTCCTG CAGGAGCAGC TGGAGCAGCT GCAGAGGGAG
TACAGCAAAC TGAAGGCCAG CTGTCAGGAG TCGGCCAGGA TCGAGGACAT GAGGAAGCGG
CATGTCGAGG TCTCCCAGGC CCCCTTGCCC CCCGCCCCTG CCTACCTCTC CTCTCCCCTG
GCCCTGCCCA GCCAGAGGAG GAGCCCCCCC GAGGAGCCAC CTGACTTCTG CTGTCCCAAG
TGCCAGTATC AGGCCCCTGA TATGGACACC CTGCAGATAC ATGTCATGGA GTGCATTGAG
TAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

 
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