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EIF3G cDNA ORF clone, Homo sapiens (human)

Gene Symbol EIF3G
Entrez Gene ID 8666
Full Name eukaryotic translation initiation factor 3, subunit G
Synonyms EIF3-P42, EIF3S4, eIF3-delta, eIF3-p44
General protein information
Preferred Names
eukaryotic translation initiation factor 3 subunit G
Names
eukaryotic translation initiation factor 3 subunit G
eIF3 p42
eIF3 p44
eIF-3-delta
eIF-3 RNA-binding subunit
eukaryotic translation initiation factor 3 subunit 4
eukaryotic translation initiation factor 3 subunit p42
eukaryotic translation initiation factor 3 RNA-binding subunit
eukaryotic translation initiation factor 3, subunit 4 delta, 44kDa
eukaryotic translation initiation factor 3, subunit 4 (delta, 44kD)
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

19

19p13.2

Summary lac of sum
Disorder MIM:

603913


mRNA and Protein(s)

mRNA Protein Name
NM_003755 NP_003746 eukaryotic translation initiation factor 3 subunit G



Homo sapiens (human) EIF3G NP_003746.2
Pan troglodytes (chimpanzee) EIF3G XP_001162705.1
Macaca mulatta (Rhesus monkey) EIF3G XP_001104633.2
Canis lupus familiaris (dog) EIF3G XP_854113.1
Bos taurus (cattle) EIF3G NP_001073091.1
Mus musculus (house mouse) Eif3g NP_058572.2
Rattus norvegicus (Norway rat) Eif3g NP_001013113.1
Gallus gallus (chicken) EIF3G XP_004950534.1
Danio rerio (zebrafish) eif3g NP_957293.1
Drosophila melanogaster (fruit fly) CG8636 NP_570011.1
Drosophila melanogaster (fruit fly) CG10881 NP_650887.1
Caenorhabditis elegans eif-3.G NP_495778.1
Xenopus (Silurana) tropicalis (western clawed frog) eif3s4 NP_001016749.1


GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following EIF3G gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the EIF3G cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu03521
NM_003755 Homo sapiens eukaryotic translation initiation factor 3, subunit G (EIF3G), mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$99.50-$139.30
$199.00
Next-day Shipping ORF Clones ( in default vector with tag)
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*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu03521
Clone ID Related Accession (Same CDS sequence) NM_003755
Accession Version NM_003755.3 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 963bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product eukaryotic translation initiation factor 3 subunit G
Comment VALIDATED REFSEQ: This record has undergone validation or preliminary review. This record has been curated by NCBI staff in collaboration with Francesco Amaldi. The reference sequence was derived from AC020931.6, BC000733.2 and BE017996.1. On Dec 6, 2005 this sequence version replaced gi:49472821. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC008469.1, AF094850.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: full length.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
ATGCCTACTG GAGACTTTGA TTCGAAGCCC AGTTGGGCCG ACCAGGTGGA GGAGGAGGGG 
GAGGACGACA AATGTGTCAC CAGCGAGCTC CTCAAGGGGA TCCCTCTGGC CACAGGTGAC
ACCAGCCCAG AGCCAGAGCT ACTGCCGGGA GCTCCACTGC CGCCTCCCAA GGAGGTCATC
AACGGAAACA TAAAGACAGT GACAGAGTAC AAGATAGATG AGGATGGCAA GAAGTTCAAG
ATTGTCCGCA CCTTCAGGAT TGAGACCCGG AAGGCTTCAA AGGCTGTCGC AAGGAGGAAG
AACTGGAAGA AGTTCGGGAA CTCAGAGTTT GACCCCCCCG GACCCAATGT GGCCACCACC
ACTGTCAGTG ACGATGTCTC TATGACGTTC ATCACCAGCA AAGAGGACCT GAACTGCCAG
GAGGAGGAGG ACCCTATGAA CAAACTCAAG GGCCAGAAGA TCGTGTCCTG CCGCATCTGC
AAGGGCGACC ACTGGACCAC CCGCTGCCCC TACAAGGATA CGCTGGGGCC CATGCAGAAG
GAGCTGGCCG AGCAGCTGGG CCTGTCTACT GGCGAGAAGG AGAAGCTGCC GGGAGAGCTA
GAGCCGGTGC AGGCCACGCA GAACAAGACA GGGAAGTATG TGCCGCCGAG CCTGCGCGAC
GGGGCCAGCC GCCGCGGGGA GTCCATGCAG CCCAACCGCA GAGCCGACGA CAACGCCACC
ATCCGTGTCA CCAACTTGTC AGAGGACACG CGTGAGACCG ACCTGCAGGA GCTCTTCCGG
CCTTTCGGCT CCATCTCCCG CATCTACCTG GCTAAGGACA AGACCACTGG CCAATCCAAG
GGCTTTGCCT TCATCAGCTT CCACCGCCGC GAGGATGCTG CGCGTGCCAT TGCCGGGGTG
TCCGGCTTTG GCTACGACCA CCTCATCCTC AACGTCGAGT GGGCCAAGCC GTCCACCAAC
TAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_003746.2
CDS65..1027
Misc Feature(1)1..1(+)
Misc Feature(2)21..21(+)
Misc Feature(3)176..178(+)
Misc Feature(4)185..187(+)
Misc Feature(5)185..187(+)
Misc Feature(6)185..187(+)
Misc Feature(7)188..190(+)
Misc Feature(8)188..190(+)
Misc Feature(9)248..583(+)
Misc Feature(10)782..1012(+)
Misc Feature(11)782..1000(+)
Exon (1)1..84
Gene:EIF3G
Gene Synonym:
Exon (2)85..131
Gene:EIF3G
Gene Synonym:
Exon (3)132..215
Gene:EIF3G
Gene Synonym:
Exon (4)216..304
Gene:EIF3G
Gene Synonym:
Exon (5)305..364
Gene:EIF3G
Gene Synonym:
Exon (6)365..469
Gene:EIF3G
Gene Synonym:
Exon (7)470..659
Gene:EIF3G
Gene Synonym:
Exon (8)660..767
Gene:EIF3G
Gene Synonym:
Exon (9)768..904
Gene:EIF3G
Gene Synonym:
Exon (10)905..1011
Gene:EIF3G
Gene Synonym:
Exon (11)1012..1127
Gene:EIF3G
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_003755
Organism Homo sapiens (human)
Definition Homo sapiens eukaryotic translation initiation factor 3, subunit G (EIF3G), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_003755

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
ATGCCTACTG GAGACTTTGA TTCGAAGCCC AGTTGGGCCG ACCAGGTGGA GGAGGAGGGG 
GAGGACGACA AATGTGTCAC CAGCGAGCTC CTCAAGGGGA TCCCTCTGGC CACAGGTGAC
ACCAGCCCAG AGCCAGAGCT ACTGCCGGGA GCTCCACTGC CGCCTCCCAA GGAGGTCATC
AACGGAAACA TAAAGACAGT GACAGAGTAC AAGATAGATG AGGATGGCAA GAAGTTCAAG
ATTGTCCGCA CCTTCAGGAT TGAGACCCGG AAGGCTTCAA AGGCTGTCGC AAGGAGGAAG
AACTGGAAGA AGTTCGGGAA CTCAGAGTTT GACCCCCCCG GACCCAATGT GGCCACCACC
ACTGTCAGTG ACGATGTCTC TATGACGTTC ATCACCAGCA AAGAGGACCT GAACTGCCAG
GAGGAGGAGG ACCCTATGAA CAAACTCAAG GGCCAGAAGA TCGTGTCCTG CCGCATCTGC
AAGGGCGACC ACTGGACCAC CCGCTGCCCC TACAAGGATA CGCTGGGGCC CATGCAGAAG
GAGCTGGCCG AGCAGCTGGG CCTGTCTACT GGCGAGAAGG AGAAGCTGCC GGGAGAGCTA
GAGCCGGTGC AGGCCACGCA GAACAAGACA GGGAAGTATG TGCCGCCGAG CCTGCGCGAC
GGGGCCAGCC GCCGCGGGGA GTCCATGCAG CCCAACCGCA GAGCCGACGA CAACGCCACC
ATCCGTGTCA CCAACTTGTC AGAGGACACG CGTGAGACCG ACCTGCAGGA GCTCTTCCGG
CCTTTCGGCT CCATCTCCCG CATCTACCTG GCTAAGGACA AGACCACTGG CCAATCCAAG
GGCTTTGCCT TCATCAGCTT CCACCGCCGC GAGGATGCTG CGCGTGCCAT TGCCGGGGTG
TCCGGCTTTG GCTACGACCA CCTCATCCTC AACGTCGAGT GGGCCAAGCC GTCCACCAAC
TAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

book

Caspase-mediated cleavage and DNase activity of the translation initiation factor 3, subunit G (eIF3g)
FEBS Lett. 587 (22), 3668-3674 (2013)
Kim JT, Lee SJ, Kim BY, Lee CH, Yeom YI, Choe YK, Yoon DY, Chae SK, Kim JW, Yang Y, Lim JS and Lee HG.


book

Translation initiation on mRNAs bound by nuclear cap-binding protein complex CBP80/20 requires interaction between CBP80/20-dependent translation initiation factor and eukaryotic translation initiation factor 3g
J. Biol. Chem. 287 (22), 18500-18509 (2012)
Choe J, Oh N, Park S, Lee YK, Song OK, Locker N, Chi SG and Kim YK.


book

Pelota interacts with HAX1, EIF3G and SRPX and the resulting protein complexes are associated with the actin cytoskeleton
BMC Cell Biol. 11, 28 (2010)
Burnicka-Turek O, Kata A, Buyandelger B, Ebermann L, Kramann N, Burfeind P, Hoyer-Fender S, Engel W and Adham IM.


book

Mass spectrometry reveals modularity and a complete subunit interaction map of the eukaryotic translation factor eIF3
Proc. Natl. Acad. Sci. U.S.A. 105 (47), 18139-18144 (2008)
Zhou M, Sandercock AM, Fraser CS, Ridlova G, Stephens E, Schenauer MR, Yokoi-Fong T, Barsky D, Leary JA, Hershey JW, Doudna JA and Robinson CV.


book

Human DDX3 functions in translation and interacts with the translation initiation factor eIF3
Nucleic Acids Res. 36 (14), 4708-4718 (2008)
Lee CS, Dias AP, Jedrychowski M, Patel AH, Hsu JL and Reed R.


book

Protein 4.1R binding to eIF3-p44 suggests an interaction between the cytoskeletal network and the translation apparatus
Blood 96 (2), 747-753 (2000)
Hou CL, Tang Cj, Roffler SR and Tang TK.


book

Cloning and characterization of the p42 subunit of mammalian translation initiation factor 3 (eIF3): demonstration that eIF3 interacts with eIF5 in mammalian cells
Nucleic Acids Res. 27 (5), 1331-1337 (1999)
Bandyopadhyay A and Maitra U.


book

Characterization of cDNAs encoding the p44 and p35 subunits of human translation initiation factor eIF3
J. Biol. Chem. 273 (48), 31901-31908 (1998)
Block KL, Vornlocher HP and Hershey JW.


book

The human homologue of the yeast Prt1 protein is an integral part of the eukaryotic initiation factor 3 complex and interacts with p170
J. Biol. Chem. 272 (2), 1110-1116 (1997)
Methot N, Rom E, Olsen H and Sonenberg N.


book

Conservation and diversity of eukaryotic translation initiation factor eIF3
J. Biol. Chem. 272 (2), 1101-1109 (1997)
Asano K, Kinzy TG, Merrick WC and Hershey JW.


 
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