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GGACT cDNA ORF clone, Homo sapiens (human)

Gene Symbol GGACT
Entrez Gene ID 87769
Full Name gamma-glutamylamine cyclotransferase
Synonyms A2LD1
General protein information
Preferred Names
gamma-glutamylaminecyclotransferase
Names
gamma-glutamylaminecyclotransferase
AIG2-like domain 1
AIG2-like domain-containing protein 1
NP_001182016.1
NP_149101.1
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

13

13q32.3

Summary The protein encoded by this gene aids in the proteolytic degradation of crosslinked fibrin by breaking down isodipeptide L-gamma-glutamyl-L-epsilon-lysine, a byproduct of fibrin degradation. The reaction catalyzed by the encoded gamma-glutamylaminecyclotransferase produces 5-oxo-L-proline and a free alkylamine. Two transcript variants encoding the same protein have been found for this gene.[provided by RefSeq, Aug 2010]. lac of sum
Disorder MIM:

613378


mRNA and Protein(s)

mRNA Protein Name
XM_011521129 XP_011519431 gamma-glutamylaminecyclotransferase isoform X1
XM_005254083 XP_005254140 gamma-glutamylaminecyclotransferase isoform X1
NM_033110 NP_149101 gamma-glutamylaminecyclotransferase
NM_001195087 NP_001182016 gamma-glutamylaminecyclotransferase


Homo sapiens (human) GGACT NP_149101.1
Pan troglodytes (chimpanzee) GGACT XP_003314249.1
Macaca mulatta (Rhesus monkey) GGACT XP_002800863.1
Canis lupus familiaris (dog) GGACT XP_005634110.1
Bos taurus (cattle) GGACT NP_001069039.1
Mus musculus (house mouse) Ggact NP_663441.1
Rattus norvegicus (Norway rat) Ggact NP_001020805.1
Gallus gallus (chicken) A2LD1 XP_004938623.1
Danio rerio (zebrafish) ggact.2 NP_001004544.1
Danio rerio (zebrafish) ggact.3 NP_001083029.1
Danio rerio (zebrafish) ggact.1 NP_001071185.1
Drosophila melanogaster (fruit fly) CG2811 NP_001246514.1
Caenorhabditis elegans F42A10.9 NP_001022574.1
Xenopus (Silurana) tropicalis (western clawed frog) ggact XP_002937126.1


GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following GGACT gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the GGACT cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu10920
XM_011521129 PREDICTED: Homo sapiens gamma-glutamylamine cyclotransferase (GGACT), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$49.50-$69.30
$99.00
OHu10920
XM_005254083 PREDICTED: Homo sapiens gamma-glutamylamine cyclotransferase (GGACT), transcript variant X2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$49.50-$69.30
$99.00
OHu10920
NM_033110 Homo sapiens gamma-glutamylamine cyclotransferase (GGACT), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$49.50-$69.30
$99.00
OHu10920
NM_001195087 Homo sapiens gamma-glutamylamine cyclotransferase (GGACT), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$49.50-$69.30
$99.00
Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone 30% OFF
2-4 Clone 40% OFF
5 or more Clone 50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu10920
Clone ID Related Accession (Same CDS sequence) NM_001195087 , NM_033110 , XM_005254083 , XM_011521129
Accession Version XM_011521129.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 462bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product gamma-glutamylaminecyclotransferase isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_009952.15) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
ATGGCCCTAG TCTTCGTGTA CGGCACCCTG AAGCGGGGTC AGCCCAACCA CAGGGTCCTG 
CGGGACGGCG CCCACGGCTC CGCAGCCTTT CGGGCGCGCG GCCGCACGCT GGAGCCCTAC
CCGTTGGTGA TCGCGGGGGA GCACAACATC CCGTGGCTGC TGCACCTGCC CGGCTCGGGG
CGCCTCGTGG AGGGCGAGGT CTACGCGGTA GACGAGCGGA TGCTGCGCTT TCTGGATGAC
TTCGAGAGTT GCCCGGCCCT GTACCAGCGC ACGGTGCTGC GGGTACAGCT GCTGGAGGAC
CGGGCCCCGG GCGCAGAGGA GCCGCCAGCG CCCACCGCGG TGCAGTGCTT CGTGTACAGC
AGGGCCACCT TCCCGCCGGA GTGGGCCCAG CTCCCGCACC ATGACAGCTA CGACTCCGAG
GGGCCGCACG GGCTGCGCTA CAACCCCCGG GAGAACAGAT AA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011519431.1
CDS3208..3669
Misc Feature(1)3217..3564(+)
Misc Feature(2)3217..3471(+)
Misc Feature(3)3367..3558(+)
Misc Feature(4)3451..3453(+)
Translation

Target ORF information:

RefSeq Version XM_011521129
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens gamma-glutamylamine cyclotransferase (GGACT), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011521129

ORF Insert Sequence:

1
61
121
181
241
301
361
421
ATGGCCCTAG TCTTCGTGTA CGGCACCCTG AAGCGGGGTC AGCCCAACCA CAGGGTCCTG 
CGGGACGGCG CCCACGGCTC CGCAGCCTTT CGGGCGCGCG GCCGCACGCT GGAGCCCTAC
CCGTTGGTGA TCGCGGGGGA GCACAACATC CCGTGGCTGC TGCACCTGCC CGGCTCGGGG
CGCCTCGTGG AGGGCGAGGT CTACGCGGTA GACGAGCGGA TGCTGCGCTT TCTGGATGAC
TTCGAGAGTT GCCCGGCCCT GTACCAGCGC ACGGTGCTGC GGGTACAGCT GCTGGAGGAC
CGGGCCCCGG GCGCAGAGGA GCCGCCAGCG CCCACCGCGG TGCAGTGCTT CGTGTACAGC
AGGGCCACCT TCCCGCCGGA GTGGGCCCAG CTCCCGCACC ATGACAGCTA CGACTCCGAG
GGGCCGCACG GGCTGCGCTA CAACCCCCGG GAGAACAGAT AA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu10920
Clone ID Related Accession (Same CDS sequence) NM_001195087 , NM_033110 , XM_005254083 , XM_011521129
Accession Version XM_005254083.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 462bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product gamma-glutamylaminecyclotransferase isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_009952.15) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
ATGGCCCTAG TCTTCGTGTA CGGCACCCTG AAGCGGGGTC AGCCCAACCA CAGGGTCCTG 
CGGGACGGCG CCCACGGCTC CGCAGCCTTT CGGGCGCGCG GCCGCACGCT GGAGCCCTAC
CCGTTGGTGA TCGCGGGGGA GCACAACATC CCGTGGCTGC TGCACCTGCC CGGCTCGGGG
CGCCTCGTGG AGGGCGAGGT CTACGCGGTA GACGAGCGGA TGCTGCGCTT TCTGGATGAC
TTCGAGAGTT GCCCGGCCCT GTACCAGCGC ACGGTGCTGC GGGTACAGCT GCTGGAGGAC
CGGGCCCCGG GCGCAGAGGA GCCGCCAGCG CCCACCGCGG TGCAGTGCTT CGTGTACAGC
AGGGCCACCT TCCCGCCGGA GTGGGCCCAG CTCCCGCACC ATGACAGCTA CGACTCCGAG
GGGCCGCACG GGCTGCGCTA CAACCCCCGG GAGAACAGAT AA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_005254140.1
CDS378..839
Misc Feature(1)387..734(+)
Misc Feature(2)387..641(+)
Misc Feature(3)537..728(+)
Misc Feature(4)621..623(+)
Translation

Target ORF information:

RefSeq Version XM_005254083
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens gamma-glutamylamine cyclotransferase (GGACT), transcript variant X2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_005254083

ORF Insert Sequence:

1
61
121
181
241
301
361
421
ATGGCCCTAG TCTTCGTGTA CGGCACCCTG AAGCGGGGTC AGCCCAACCA CAGGGTCCTG 
CGGGACGGCG CCCACGGCTC CGCAGCCTTT CGGGCGCGCG GCCGCACGCT GGAGCCCTAC
CCGTTGGTGA TCGCGGGGGA GCACAACATC CCGTGGCTGC TGCACCTGCC CGGCTCGGGG
CGCCTCGTGG AGGGCGAGGT CTACGCGGTA GACGAGCGGA TGCTGCGCTT TCTGGATGAC
TTCGAGAGTT GCCCGGCCCT GTACCAGCGC ACGGTGCTGC GGGTACAGCT GCTGGAGGAC
CGGGCCCCGG GCGCAGAGGA GCCGCCAGCG CCCACCGCGG TGCAGTGCTT CGTGTACAGC
AGGGCCACCT TCCCGCCGGA GTGGGCCCAG CTCCCGCACC ATGACAGCTA CGACTCCGAG
GGGCCGCACG GGCTGCGCTA CAACCCCCGG GAGAACAGAT AA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu10920
Clone ID Related Accession (Same CDS sequence) NM_001195087 , NM_033110 , XM_005254083 , XM_011521129
Accession Version NM_033110.2 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 462bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product gamma-glutamylaminecyclotransferase
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA628207.1 and AL136526.27. On Aug 19, 2010 this sequence version replaced gi:34147452. Transcript Variant: This variant (1) represents the longer transcript. Both variants encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: DA628207.1, BC001077.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
ATGGCCCTAG TCTTCGTGTA CGGCACCCTG AAGCGGGGTC AGCCCAACCA CAGGGTCCTG 
CGGGACGGCG CCCACGGCTC CGCAGCCTTT CGGGCGCGCG GCCGCACGCT GGAGCCCTAC
CCGTTGGTGA TCGCGGGGGA GCACAACATC CCGTGGCTGC TGCACCTGCC CGGCTCGGGG
CGCCTCGTGG AGGGCGAGGT CTACGCGGTA GACGAGCGGA TGCTGCGCTT TCTGGATGAC
TTCGAGAGTT GCCCGGCCCT GTACCAGCGC ACGGTGCTGC GGGTACAGCT GCTGGAGGAC
CGGGCCCCGG GCGCAGAGGA GCCGCCAGCG CCCACCGCGG TGCAGTGCTT CGTGTACAGC
AGGGCCACCT TCCCGCCGGA GTGGGCCCAG CTCCCGCACC ATGACAGCTA CGACTCCGAG
GGGCCGCACG GGCTGCGCTA CAACCCCCGG GAGAACAGAT AA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_149101.1
CDS251..712
Misc Feature(1)23..25(+)
Misc Feature(2)260..607(+)
Misc Feature(3)260..514(+)
Misc Feature(4)269..280(+)
Misc Feature(5)410..601(+)
Misc Feature(6)494..496(+)
Exon (1)1..240
Gene:GGACT
Gene Synonym:
Exon (2)241..2678
Gene:GGACT
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_033110
Organism Homo sapiens (human)
Definition Homo sapiens gamma-glutamylamine cyclotransferase (GGACT), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_033110

ORF Insert Sequence:

1
61
121
181
241
301
361
421
ATGGCCCTAG TCTTCGTGTA CGGCACCCTG AAGCGGGGTC AGCCCAACCA CAGGGTCCTG 
CGGGACGGCG CCCACGGCTC CGCAGCCTTT CGGGCGCGCG GCCGCACGCT GGAGCCCTAC
CCGTTGGTGA TCGCGGGGGA GCACAACATC CCGTGGCTGC TGCACCTGCC CGGCTCGGGG
CGCCTCGTGG AGGGCGAGGT CTACGCGGTA GACGAGCGGA TGCTGCGCTT TCTGGATGAC
TTCGAGAGTT GCCCGGCCCT GTACCAGCGC ACGGTGCTGC GGGTACAGCT GCTGGAGGAC
CGGGCCCCGG GCGCAGAGGA GCCGCCAGCG CCCACCGCGG TGCAGTGCTT CGTGTACAGC
AGGGCCACCT TCCCGCCGGA GTGGGCCCAG CTCCCGCACC ATGACAGCTA CGACTCCGAG
GGGCCGCACG GGCTGCGCTA CAACCCCCGG GAGAACAGAT AA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu10920
Clone ID Related Accession (Same CDS sequence) NM_001195087 , NM_033110 , XM_005254083 , XM_011521129
Accession Version NM_001195087.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 462bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product gamma-glutamylaminecyclotransferase
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK095850.1 and AL136526.27. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: AK095850.1, DA636234.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA962337 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
ATGGCCCTAG TCTTCGTGTA CGGCACCCTG AAGCGGGGTC AGCCCAACCA CAGGGTCCTG 
CGGGACGGCG CCCACGGCTC CGCAGCCTTT CGGGCGCGCG GCCGCACGCT GGAGCCCTAC
CCGTTGGTGA TCGCGGGGGA GCACAACATC CCGTGGCTGC TGCACCTGCC CGGCTCGGGG
CGCCTCGTGG AGGGCGAGGT CTACGCGGTA GACGAGCGGA TGCTGCGCTT TCTGGATGAC
TTCGAGAGTT GCCCGGCCCT GTACCAGCGC ACGGTGCTGC GGGTACAGCT GCTGGAGGAC
CGGGCCCCGG GCGCAGAGGA GCCGCCAGCG CCCACCGCGG TGCAGTGCTT CGTGTACAGC
AGGGCCACCT TCCCGCCGGA GTGGGCCCAG CTCCCGCACC ATGACAGCTA CGACTCCGAG
GGGCCGCACG GGCTGCGCTA CAACCCCCGG GAGAACAGAT AA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001182016.1
CDS236..697
Misc Feature(1)191..193(+)
Misc Feature(2)245..592(+)
Misc Feature(3)245..499(+)
Misc Feature(4)254..265(+)
Misc Feature(5)395..586(+)
Misc Feature(6)479..481(+)
Exon (1)1..52
Gene:GGACT
Gene Synonym:
Exon (2)53..225
Gene:GGACT
Gene Synonym:
Exon (3)226..2663
Gene:GGACT
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_001195087
Organism Homo sapiens (human)
Definition Homo sapiens gamma-glutamylamine cyclotransferase (GGACT), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001195087

ORF Insert Sequence:

1
61
121
181
241
301
361
421
ATGGCCCTAG TCTTCGTGTA CGGCACCCTG AAGCGGGGTC AGCCCAACCA CAGGGTCCTG 
CGGGACGGCG CCCACGGCTC CGCAGCCTTT CGGGCGCGCG GCCGCACGCT GGAGCCCTAC
CCGTTGGTGA TCGCGGGGGA GCACAACATC CCGTGGCTGC TGCACCTGCC CGGCTCGGGG
CGCCTCGTGG AGGGCGAGGT CTACGCGGTA GACGAGCGGA TGCTGCGCTT TCTGGATGAC
TTCGAGAGTT GCCCGGCCCT GTACCAGCGC ACGGTGCTGC GGGTACAGCT GCTGGAGGAC
CGGGCCCCGG GCGCAGAGGA GCCGCCAGCG CCCACCGCGG TGCAGTGCTT CGTGTACAGC
AGGGCCACCT TCCCGCCGGA GTGGGCCCAG CTCCCGCACC ATGACAGCTA CGACTCCGAG
GGGCCGCACG GGCTGCGCTA CAACCCCCGG GAGAACAGAT AA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

 
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