The following SYNGAP1 gene sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SYNGAP1 gene which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
||Documents for ORF clone product in dufault vector
||ORF Nucleotide Sequence (Length: 4032bp)
||pcDNA3.1+/C-(K)DYK or customized vector
|Tag on pcDNA3.1+/C-(K)DYK
||C terminal DYKDDDDK tags
|ORF Insert Method
||CloneEZ® Seamless cloning technology
||Homo sapiens (human)
||ras/Rap GTPase-activating protein SynGAP
||REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from DA057307.1, AK307888.1,
AK094225.1, AL713634.1, BX282051.1 and BM354009.1.
This sequence is a reference standard in the RefSeqGene project.
On Jul 15, 2008 this sequence version replaced gi:54607095.
Summary: The protein encoded by this gene is a major component of
the postsynaptic density (PSD), a group of proteins found
associated with NMDA receptors at synapses. The encoded protein is
phosphorylated by calmodulin-dependent protein kinase II and
dephosphorylated by NMDA receptor activation. Defects in this gene
are a cause of mental retardation autosomal dominant type 5 (MRD5).
[provided by RefSeq, Dec 2009].
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
RNAseq introns :: single sample supports all introns SAMEA1966682,
COMPLETENESS: complete on the 3' end.