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EIF2B2 cDNA ORF clone, Homo sapiens (human)

Gene Symbol EIF2B2
Entrez Gene ID 8892
Full Name eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa
Synonyms EIF-2Bbeta, EIF2B
General protein information
Preferred Names
translation initiation factor eIF-2B subunit beta
Names
translation initiation factor eIF-2B subunit beta
S20I15
S20III15
eIF-2B GDP-GTP exchange factor subunit beta
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

14

14q24.3

Summary This gene encodes the beta subunit of eukaryotic initiation factor-2B (EIF2B). EIF2B is involved in protein synthesis and exchanges GDP and GTP for its activation and deactivation. [provided by RefSeq, Aug 2011]. lac of sum
Disorder MIM:

606454

Disorder Html: Leukoencephalopathy with vanishing white matter, 603896 (3);





The following EIF2B2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the EIF2B2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu22319 NM_014239 Homo sapiens eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa (EIF2B2), mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$265.30
$379.00

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**You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.


CloneID OHu22319
Accession Version NM_014239.3 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1056bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product translation initiation factor eIF-2B subunit beta
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff in collaboration with Francesco Amaldi. The reference sequence was derived from AL049780.4, BC011750.2 and AI265790.1. This sequence is a reference standard in the RefSeqGene project. On Oct 10, 2009 this sequence version replaced gi:77404352. Summary: This gene encodes the beta subunit of eukaryotic initiation factor-2B (EIF2B). EIF2B is involved in protein synthesis and exchanges GDP and GTP for its activation and deactivation. [provided by RefSeq, Aug 2011]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC000494.2, AF035280.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
ATGCCGGGAT CCGCAGCGAA GGGCTCGGAG TTGTCAGAGA GGATCGAGAG CTTCGTGGAG 
ACCCTGAAGC GGGGTGGTGG GCCGCGCAGC TCCGAGGAAA TGGCTCGGGA GACCCTAGGG
TTGCTGCGCC AGATCATCAC GGACCACCGC TGGAGCAACG CGGGGGAGCT GATGGAGCTG
ATCCGCAGAG AGGGCAGGAG GATGACGGCC GCTCAGCCCT CCGAGACCAC CGTGGGCAAC
ATGGTGCGGA GAGTGCTCAA GATTATCCGG GAGGAGTATG GCAGACTCCA TGGACGCAGC
GACGAGAGTG ATCAGCAGGA GTCCCTGCAC AAACTGTTGA CATCCGGAGG CCTAAACGAG
GATTTCAGCT TCCATTATGC CCAACTCCAG TCCAACATCA TTGAGGCGAT TAATGAGCTG
CTAGTGGAGC TGGAAGGGAC AATGGAGAAC ATTGCAGCCC AGGCTCTGGA GCACATTCAC
TCCAATGAGG TGATCATGAC CATTGGCTTC TCCCGAACAG TAGAGGCCTT CCTCAAAGAG
GCTGCCCGAA AGAGGAAATT CCATGTCATT GTAGCAGAGT GTGCTCCTTT CTGCCAGGGT
CATGAAATGG CTGTGAATTT GTCCAAAGCA GGTATTGAGA CAACTGTCAT GACTGATGCT
GCCATTTTTG CCGTTATGTC AAGAGTCAAC AAGGTGATCA TTGGCACGAA GACCATCCTG
GCCAATGGGG CCCTGAGAGC TGTGACAGGA ACTCACACTC TGGCACTGGC AGCAAAACAC
CATTCCACCC CACTCATCGT CTGTGCACCT ATGTTCAAAC TTTCTCCACA GTTCCCCAAT
GAAGAAGACT CATTTCATAA GTTTGTGGCT CCTGAAGAAG TCCTGCCATT CACAGAAGGG
GACATTCTGG AGAAGGTCAG CGTGCATTGC CCTGTGTTTG ACTACGTTCC CCCAGAGCTC
ATTACCCTCT TTATCTCCAA CATTGGTGGG AATGCACCTT CCTACATCTA CCGCCTGATG
AGTGAACTCT ACCATCCTGA TGATCATGTT TTATGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeqNP_055054.1
CDS83..1138
Misc Feature(1)56..58(+)
Misc Feature(2)167..1114(+)
Misc Feature(3)167..1081(+)
Exon (1)1..245
Gene:EIF2B2
Gene Synonym:
Exon (2)246..366
Gene:EIF2B2
Gene Synonym:
Exon (3)367..515
Gene:EIF2B2
Gene Synonym:
Exon (4)516..679
Gene:EIF2B2
Gene Synonym:
Exon (5)680..775
Gene:EIF2B2
Gene Synonym:
Exon (6)776..913
Gene:EIF2B2
Gene Synonym:
Exon (7)914..980
Gene:EIF2B2
Gene Synonym:
Exon (8)981..1541
Gene:EIF2B2
Gene Synonym:
Translation
Position Chain Variation Link
8 8 c, g dbSNP:753978497
23 23 a, g dbSNP:200557826
27 27 c, t dbSNP:201368910
33 33 c, g, t dbSNP:555674467
39 39 -, ggtgt dbSNP:534085536
49 49 c, g, t dbSNP:752293505
50 50 c, t dbSNP:777639623
53 53 c, g, t dbSNP:746984359
61 61 g, t dbSNP:781057047
62 62 c, t dbSNP:746067582
63 63 c, t dbSNP:770117655
67 67 a, g dbSNP:775398859
71 71 g, t dbSNP:199626686
72 72 -, ct dbSNP:758891991
72 72 c, g dbSNP:374771844
78 78 c, t dbSNP:768878879
81 81 a, c, t dbSNP:774957796
83 83 a, g dbSNP:199671360
85 85 g, t dbSNP:767933078
87 87 c, t dbSNP:773695426
89 89 a, g dbSNP:759080911
94 94 a, c dbSNP:764989690
97 97 a, c dbSNP:752315506
98 98 c, g dbSNP:757868212
99 99 c, g dbSNP:763602964
112 112 a, g dbSNP:751443080
114 114 c, t dbSNP:757245015
120 120 a, g dbSNP:780841869
128 128 c, g dbSNP:776788187
130 130 a, g dbSNP:745712923
131 131 a, g dbSNP:756263862
132 132 a, g dbSNP:780269972
133 133 c, t dbSNP:749552337
134 134 c, t dbSNP:768788808
145 145 c, t dbSNP:774585521
146 146 c, t dbSNP:143091762
149 149 a, c dbSNP:772748876
150 150 a, g dbSNP:773429046
158 158 a, c, g dbSNP:141355163
159 159 a, g dbSNP:369180674
163 163 a, g dbSNP:762611298
165 165 c, t dbSNP:763584691
166 166 c, g dbSNP:144753546
167 167 c, t dbSNP:761706101
169 169 c, t dbSNP:767536443
171 171 a, g dbSNP:529670879
178 178 a, g dbSNP:146228503
199 199 a, g dbSNP:755897515
201 201 c, g dbSNP:139325888
202 202 a, g dbSNP:754054549
209 209 c, t dbSNP:372838502
214 214 c, g dbSNP:779106104
218 218 a, g dbSNP:748288181
220 220 c, t dbSNP:772067107
222 222 c, g dbSNP:778303902
225 225 -, acc dbSNP:780480791
226 226 c, g dbSNP:747480025
230 230 c, t dbSNP:771272417
233 233 c, t dbSNP:777041434
234 234 g, t dbSNP:553824476
237 237 a, g dbSNP:768335115
241 241 c, g dbSNP:773826562
244 244 a, c, g dbSNP:761260701
245 245 a, g dbSNP:750307992
254 254 a, t dbSNP:752913982
264 264 c, t dbSNP:758611010
265 265 c, t dbSNP:764232354
268 268 c, t dbSNP:751634475
278 278 a, g dbSNP:757757428
288 288 c, g dbSNP:781626544
295 295 a, t dbSNP:369511014
302 302 c, t dbSNP:756401063
304 304 c, t dbSNP:780409528
308 308 a, g dbSNP:747822193
313 313 c, t dbSNP:771686725
314 314 a, g dbSNP:772745651
316 316 c, g dbSNP:142827960
320 320 a, c dbSNP:775188722
321 321 a, g dbSNP:746456163
323 323 a, g dbSNP:770598243
324 324 a, t dbSNP:377659896
336 336 a, t dbSNP:397514648
343 343 c, g dbSNP:538163666
373 373 g, t dbSNP:750568077
380 380 a, t dbSNP:368133564
381 381 c, g dbSNP:17849324
393 393 a, g dbSNP:766843755
407 407 c, t dbSNP:370483997
415 415 a, c, g dbSNP:759621968
424 424 a, t dbSNP:755232669
427 427 c, t dbSNP:779349624
428 428 a, g dbSNP:751159755
436 436 a, g dbSNP:374195020
437 437 a, c dbSNP:368343040
449 449 a, g dbSNP:745423619
454 454 c, t dbSNP:769455036
462 462 c, g, t dbSNP:150617429
464 464 a, c dbSNP:200642949
466 466 a, g dbSNP:372174903
482 482 -, att dbSNP:777077732
483 483 c, t dbSNP:201622896
487 487 g, t dbSNP:201912801
489 489 c, t dbSNP:762017222
490 490 a, g dbSNP:772320060
491 491 -, t dbSNP:748297529
505 505 a, g dbSNP:773252033
523 523 a, g dbSNP:764538257
529 529 a, g dbSNP:35602124
534 534 c, t dbSNP:774920663
537 537 c, t dbSNP:760213491
544 544 a, g dbSNP:766102981
566 566 a, g dbSNP:753454455
567 567 a, g dbSNP:754470588
573 573 c, g, t dbSNP:11628782
575 575 -, t dbSNP:765855445
580 580 a, g dbSNP:139680549
584 584 a, g dbSNP:779627622
594 594 c, t dbSNP:104894428
596 596 c, t dbSNP:758398310
603 603 c, t dbSNP:777514938
610 610 c, t dbSNP:751422883
618 618 a, g dbSNP:757027574
622 622 c, g dbSNP:781440489
623 623 g, t dbSNP:746086054
629 629 c, t dbSNP:104894427
630 630 a, g dbSNP:369078986
630 630 -, g dbSNP:113994010
651 651 -, t dbSNP:755436800
652 652 c, g, t dbSNP:749806505
664 664 a, t dbSNP:774832957
665 665 g, t dbSNP:547439570
668 668 c, t dbSNP:113994011
680 680 a, g dbSNP:149784396
681 681 c, g, t dbSNP:113994012
687 687 -, a dbSNP:771315757
689 689 atggct, tg dbSNP:113994014
692 692 -, gct dbSNP:778851276
703 703 g, t dbSNP:75302306
712 712 a, g dbSNP:111702244
716 716 a, g dbSNP:761711297
720 720 a, g dbSNP:104894425
735 735 c, g dbSNP:750222755
746 746 a, g dbSNP:142977089
754 754 c, t dbSNP:528714025
755 755 a, g dbSNP:754142566
759 759 c, t dbSNP:369821050
759 759 -, t dbSNP:746013265
760 760 a, g dbSNP:778871859
764 764 a, c, g dbSNP:748685143
771 771 a, g dbSNP:778179219
782 782 a, g dbSNP:758530283
789 789 c, t dbSNP:778105211
790 790 a, g dbSNP:747522516
796 796 c, t dbSNP:748270202
800 800 c, t dbSNP:781598625
807 807 a, g dbSNP:200594436
815 815 c, t dbSNP:769747721
816 816 c, t dbSNP:527818198
817 817 a, g, t dbSNP:748930802
839 839 a, c dbSNP:773887336
840 840 a, c, t dbSNP:778122213
844 844 c, g dbSNP:771642041
867 867 -, ccacc dbSNP:776563872
868 868 c, t dbSNP:773215545
877 877 c, t dbSNP:760700392
878 878 -, at dbSNP:748113480
880 880 c, t dbSNP:766262644
881 881 a, g dbSNP:776608965
883 883 -, c dbSNP:769527374
893 893 a, g dbSNP:759810972
897 897 c, t dbSNP:373405948
900 900 a, g dbSNP:113994016
905 905 c, t dbSNP:762878400
906 906 a, c dbSNP:764250744
911 911 c, t dbSNP:374037958
912 912 a, g dbSNP:752052897
916 916 c, t dbSNP:758137309
917 917 c, t dbSNP:142553958
921 921 a, g dbSNP:746469083
926 926 c, g dbSNP:770598173
928 928 a, c dbSNP:781211698
940 940 c, t dbSNP:745833840
945 945 c, t dbSNP:376944725
947 947 g, t dbSNP:775427018
953 953 c, t dbSNP:113994017
954 954 c, t dbSNP:763050699
957 957 a, c dbSNP:768911925
966 966 c, t dbSNP:774575817
968 968 c, t dbSNP:761839092
971 971 -, t dbSNP:773041356
983 983 a, g dbSNP:749059127
992 992 g, t dbSNP:113994018
993 993 -, aga dbSNP:762563184
1003 1003 c, t dbSNP:768467979
1004 1004 a, c, g dbSNP:372548739
1009 1009 c, t dbSNP:138817058
1012 1012 c, t dbSNP:767183422
1024 1024 c, t dbSNP:772125418
1027 1027 c, t dbSNP:773407374
1028 1028 a, g dbSNP:761055346
1029 1029 a, t dbSNP:104894426
1036 1036 a, c dbSNP:777036076
1042 1042 c, t dbSNP:759914845
1046 1046 -, acc dbSNP:766123244
1055 1055 a, g dbSNP:765712931
1061 1061 a, t dbSNP:577844198
1062 1062 a, g dbSNP:200849948
1064 1064 a, g dbSNP:145117455
1066 1066 c, t dbSNP:375585987
1068 1068 g, t dbSNP:113994020
1074 1074 a, g dbSNP:749995021
1081 1081 a, t dbSNP:147596765
1087 1087 c, t dbSNP:779998988
1090 1090 c, t dbSNP:140707986
1093 1093 c, t dbSNP:754711911
1123 1123 -, g dbSNP:773725419
1125 1125 -, atc dbSNP:759031496
1134 1134 c, t dbSNP:778740286
1140 1140 c, t dbSNP:373439468
1141 1141 c, g dbSNP:112087431
1143 1143 a, c dbSNP:773328951
1144 1144 c, t dbSNP:747070752
1148 1148 c, g, t dbSNP:770918340
1149 1149 a, g dbSNP:370756093
1151 1151 a, g dbSNP:770275347
1163 1163 c, t dbSNP:776033447
1164 1164 g, t dbSNP:761530281
1171 1171 a, g dbSNP:375056192
1176 1176 -, tgcttaggcagat dbSNP:372474383
1176 1176 c, t dbSNP:750077642
1178 1178 a, c dbSNP:760167860
1183 1183 g, t dbSNP:765822635
1186 1186 a, c dbSNP:199523469
1187 1187 -, gag dbSNP:766944047
1194 1194 c, t dbSNP:116393177
1204 1204 g, t dbSNP:560892827
1248 1248 a, c dbSNP:3208685
1275 1275 -, tgcc dbSNP:760892259
1296 1296 c, t dbSNP:530228507
1297 1297 a, g dbSNP:187228528
1307 1307 c, t dbSNP:566966733
1312 1312 a, g dbSNP:542050883
1318 1318 c, g dbSNP:4556
1319 1319 a, g dbSNP:552563342
1364 1364 -, ttg dbSNP:763277044
1380 1380 -, ct dbSNP:541027518
1398 1398 c, t dbSNP:569575124
1425 1425 g, t dbSNP:746045033
1506 1506 c, t dbSNP:1058367
1526 1526 c, t dbSNP:141381011
1539 1539 a, c dbSNP:3180290

Target ORF information:

RefSeq Version NM_014239
Organism Homo sapiens (human)
Definition Homo sapiens eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa (EIF2B2), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_014239

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
ATGCCGGGAT CCGCAGCGAA GGGCTCGGAG TTGTCAGAGA GGATCGAGAG CTTCGTGGAG 
ACCCTGAAGC GGGGTGGTGG GCCGCGCAGC TCCGAGGAAA TGGCTCGGGA GACCCTAGGG
TTGCTGCGCC AGATCATCAC GGACCACCGC TGGAGCAACG CGGGGGAGCT GATGGAGCTG
ATCCGCAGAG AGGGCAGGAG GATGACGGCC GCTCAGCCCT CCGAGACCAC CGTGGGCAAC
ATGGTGCGGA GAGTGCTCAA GATTATCCGG GAGGAGTATG GCAGACTCCA TGGACGCAGC
GACGAGAGTG ATCAGCAGGA GTCCCTGCAC AAACTGTTGA CATCCGGAGG CCTAAACGAG
GATTTCAGCT TCCATTATGC CCAACTCCAG TCCAACATCA TTGAGGCGAT TAATGAGCTG
CTAGTGGAGC TGGAAGGGAC AATGGAGAAC ATTGCAGCCC AGGCTCTGGA GCACATTCAC
TCCAATGAGG TGATCATGAC CATTGGCTTC TCCCGAACAG TAGAGGCCTT CCTCAAAGAG
GCTGCCCGAA AGAGGAAATT CCATGTCATT GTAGCAGAGT GTGCTCCTTT CTGCCAGGGT
CATGAAATGG CTGTGAATTT GTCCAAAGCA GGTATTGAGA CAACTGTCAT GACTGATGCT
GCCATTTTTG CCGTTATGTC AAGAGTCAAC AAGGTGATCA TTGGCACGAA GACCATCCTG
GCCAATGGGG CCCTGAGAGC TGTGACAGGA ACTCACACTC TGGCACTGGC AGCAAAACAC
CATTCCACCC CACTCATCGT CTGTGCACCT ATGTTCAAAC TTTCTCCACA GTTCCCCAAT
GAAGAAGACT CATTTCATAA GTTTGTGGCT CCTGAAGAAG TCCTGCCATT CACAGAAGGG
GACATTCTGG AGAAGGTCAG CGTGCATTGC CCTGTGTTTG ACTACGTTCC CCCAGAGCTC
ATTACCCTCT TTATCTCCAA CATTGGTGGG AATGCACCTT CCTACATCTA CCGCCTGATG
AGTGAACTCT ACCATCCTGA TGATCATGTT TTATGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

 
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