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CCNA1 cDNA ORF clone, Homo sapiens (human)

Gene Symbol CCNA1
Entrez Gene ID 8900
Full Name cyclin A1
Synonyms CT146
General protein information
Preferred Names
cyclin-A1
Names
cyclin-A1
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

13

13q12.3-q13

Summary The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. The cyclin encoded by this gene was shown to be expressed in testis and brain, as well as in several leukemic cell lines, and is thought to primarily function in the control of the germline meiotic cell cycle. This cyclin binds both CDK2 and CDC2 kinases, which give two distinct kinase activities, one appearing in S phase, the other in G2, and thus regulate separate functions in cell cycle. This cyclin was found to bind to important cell cycle regulators, such as Rb family proteins, transcription factor E2F-1, and the p21 family proteins. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]. lac of sum
Disorder MIM:

604036

Disorder Html:





The following CCNA1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CCNA1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu25352 XM_011535294 PREDICTED: Homo sapiens cyclin A1 (CCNA1), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 5-7 $319.00
OHu25352 XM_011535295 PREDICTED: Homo sapiens cyclin A1 (CCNA1), transcript variant X2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 5-7 $319.00
OHu25352 XM_011535296 PREDICTED: Homo sapiens cyclin A1 (CCNA1), transcript variant X3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 5-7 $319.00
OHu25352 XM_011535297 PREDICTED: Homo sapiens cyclin A1 (CCNA1), transcript variant X4, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 5-7 $319.00
OHu25389 NM_003914 Homo sapiens cyclin A1 (CCNA1), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $379.00
OHu25558 NM_001111045 Homo sapiens cyclin A1 (CCNA1), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 5-7 $379.00
OHu25352 NM_001111046 Homo sapiens cyclin A1 (CCNA1), transcript variant 3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 5-7 $319.00
OHu25352 NM_001111047 Homo sapiens cyclin A1 (CCNA1), transcript variant 4, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $319.00

*Business Day
**You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.


CloneID OHu25352
Accession Version XM_011535294.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1266bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product cyclin-A1 isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_024524.15) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
ATGCACTGCA GCAACCCCAA GAGTGGAGTT GTGCTGGCTA CAGTGGCCCG AGGTCCCGAT 
GCTTGTCAGA TACTCACCAG AGCCCCGCTG GGCCAGGATC CCCCGCAGAG GACAGTGCTA
GGGCTGCTAA CTGCAAATGG GCAGTACAGG AGGACCTGTG GCCAGGGGAT CACAAGAATC
AGGTGTTATT CTGGATCAGA AAATGCCTTC CCTCCAGCTG GAAAGAAAGC ACTCCCTGAC
TGTGGGGTCC AAGAGCCCCC CAAGCAAGGG TTTGACATCT ACATGGATGA ACTAGAGCAG
GGGGACAGAG ACAGCTGCTC GGTCAGAGAG GGGATGGCAT TTGAGGATGT GTATGAAGTA
GACACCGGCA CACTCAAGTC AGACCTGCAC TTCCTGCTGG ATTTCAACAC AGTTTCCCCT
ATGCTGGTAG ATTCATCTCT CCTCTCCCAG TCTGAAGATA TATCCAGTCT TGGCACAGAT
GTGATAAATG TGACTGAATA TGCTGAAGAA ATTTATCAGT ACCTTAGGGA AGCTGAAATA
AGGCACAGAC CCAAAGCACA CTACATGAAG AAGCAGCCAG ACATCACGGA AGGCATGCGC
ACGATTCTGG TGGACTGGCT GGTGGAGGTT GGGGAAGAAT ATAAACTTCG AGCAGAGACC
CTGTATCTGG CTGTCAACTT CCTGGACAGG TTCCTTTCAT GTATGTCTGT TCTGAGAGGG
AAACTGCAGC TCGTAGGAAC AGCAGCTATG CTTTTGGCTT CGAAATATGA AGAGATATAT
CCTCCTGAAG TAGACGAGTT TGTCTATATC ACCGATGATA CATACACAAA ACGACAACTG
TTAAAAATGG AACACTTGCT TCTGAAAGTT CTAGCTTTTG ATCTGACAGT ACCAACCACC
AACCAGTTTC TCCTTCAGTA CTTGAGGCGA CAAGGAGTGT GCGTCAGGAC TGAGAACCTG
GCTAAGTACG TAGCAGAGCT GAGTCTACTT GAAGCAGATC CATTCTTGAA ATATCTTCCT
TCACTGATAG CTGCAGCAGC TTTTTGCCTG GCAAACTATA CTGTGAACAA GCACTTTTGG
CCAGAAACCC TTGCTGCATT TACAGGGTAT TCATTAAGTG AAATTGTGCC TTGCCTGAGT
GAGCTTCATA AAGCGTACCT TGATATACCC CATCGACCTC AGCAAGCAAT TAGGGAGAAG
TACAAGGCTT CAAAGTACCT GTGTGTGTCC CTCATGGAGC CACCTGCAGT TCTTCTTCTA
CAATAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeqXP_011533596.1
CDS772..2037
Misc Feature(1)1366..1635(+)
Misc Feature(2)1366..1500(+)
Misc Feature(3)1522..1623(+)
Misc Feature(4)1657..1920(+)
Misc Feature(5)1657..1794(+)
Misc Feature(6)1816..1908(+)
Translation
Position Chain Variation Link
14 14 c, g dbSNP:79637235
35 35 g, t dbSNP:545995822
44 44 a, c dbSNP:115732208
73 73 c, g dbSNP:563774417
77 77 a, c dbSNP:116168763
78 78 c, t dbSNP:549132723
105 105 a, g dbSNP:772739621
107 107 c, g dbSNP:149008909
124 124 g, t dbSNP:3829944
143 143 a, g dbSNP:776794197
149 149 c, t dbSNP:546916173
193 193 c, t dbSNP:571109466
202 202 a, t dbSNP:538451419
227 227 -, ta dbSNP:555180235
231 231 -, a dbSNP:760771229
243 243 a, g dbSNP:760014241
271 271 a, t dbSNP:112307354
272 272 a, t dbSNP:568624584
285 285 g, t dbSNP:548540595
319 319 c, t dbSNP:554242865
346 346 a, g dbSNP:572828672
363 363 a, c dbSNP:534996997
442 442 a, c dbSNP:115056545
469 469 a, c dbSNP:578182289
480 480 c, t dbSNP:545634068
488 488 a, g dbSNP:775833724
495 495 g, t dbSNP:760198443
535 535 g, t dbSNP:557464962
563 563 c, g dbSNP:575627370
573 573 c, g dbSNP:3829943
587 587 a, t dbSNP:561118523
590 590 c, g dbSNP:528536753
624 624 a, g dbSNP:753367685
639 639 c, g dbSNP:540091397
643 643 c, g dbSNP:541143574
659 659 -, a dbSNP:35326131
667 667 a, c dbSNP:376841838
683 683 a, c dbSNP:532138212
684 684 a, c dbSNP:373607677
703 703 a, g dbSNP:550380815
733 733 c, t dbSNP:569058337
753 753 c, g dbSNP:141476503
762 762 a, g dbSNP:755391943
771 771 a, g dbSNP:779524233
777 777 c, t dbSNP:147007878
780 780 -, cagcaa dbSNP:763106197
783 783 c, g, t dbSNP:377589059
788 788 c, t dbSNP:142133640
789 789 c, t dbSNP:151081377
792 792 a, g dbSNP:746609003
794 794 a, g dbSNP:145220476
800 800 c, t dbSNP:560118670
811 811 a, g dbSNP:370964964
813 813 a, g dbSNP:759393578
817 817 a, g dbSNP:769594081
828 828 c, t dbSNP:149125997
833 833 c, t dbSNP:761793251
837 837 c, t dbSNP:767691805
841 841 a, t dbSNP:368007173
850 850 a, g dbSNP:143296005
856 856 c, g dbSNP:370590641
857 857 c, g dbSNP:760912284
865 865 c, t dbSNP:766731424
866 866 a, g dbSNP:754232617
867 867 c, g dbSNP:540233147
871 871 c, g, t dbSNP:552343736
874 874 c, t dbSNP:753307734
875 875 a, c dbSNP:746200537
876 876 a, g dbSNP:758844418
882 882 a, g dbSNP:201226091
888 888 a, g dbSNP:148316727
910 910 a, g dbSNP:746557549
947 947 a, g dbSNP:751042420
949 949 a, g dbSNP:756797263
951 951 c, g dbSNP:780816141
952 952 a, t dbSNP:575517029
954 954 a, g dbSNP:772777206
957 957 c, t dbSNP:779831451
960 960 c, t dbSNP:61729896
985 985 c, t dbSNP:768692826
986 986 c, t dbSNP:774471192
989 989 c, g, t dbSNP:747082248
1002 1002 a, g dbSNP:145829125
1017 1017 a, g dbSNP:759740467
1018 1018 g, t dbSNP:765412925
1020 1020 a, c dbSNP:775879131
1021 1021 c, g dbSNP:763352839
1026 1026 -, c dbSNP:777748261
1026 1026 a, g dbSNP:764550152
1027 1027 c, g, t dbSNP:574280988
1028 1028 c, g dbSNP:367588569
1029 1029 a, c dbSNP:749904346
1031 1031 c, g dbSNP:755751093
1041 1041 a, g, t dbSNP:779594513
1054 1054 a, g dbSNP:754888442
1064 1064 a, t dbSNP:61733784
1072 1072 a, g dbSNP:371431411
1075 1075 g, t dbSNP:748042719
1083 1083 c, t dbSNP:772143355
1091 1091 c, t dbSNP:143100244
1092 1092 a, g, t dbSNP:368505689
1094 1094 c, t dbSNP:765937307
1096 1096 -, ag dbSNP:753784627
1097 1097 a, g dbSNP:540179877
1102 1102 a, g dbSNP:763296052
1103 1103 g, t dbSNP:769065045
1106 1106 c, t dbSNP:113260257
1114 1114 a, g dbSNP:199835821
1121 1121 a, t dbSNP:374907767
1122 1122 a, g dbSNP:767940034
1128 1128 a, g dbSNP:753412232
1131 1131 a, g dbSNP:760144028
1137 1137 c, t dbSNP:766051820
1138 1138 a, g dbSNP:753604464
1144 1144 c, t dbSNP:754694176
1147 1147 a, g dbSNP:368185225
1155 1155 c, t dbSNP:201364984
1158 1158 a, g dbSNP:758365529
1160 1160 a, g dbSNP:777624140
1178 1178 a, g dbSNP:200724447
1179 1179 c, t dbSNP:769827681
1180 1180 a, g dbSNP:780306675
1182 1182 a, g dbSNP:749452494
1187 1187 c, t dbSNP:778026294
1192 1192 a, g dbSNP:757229441
1196 1196 c, t dbSNP:780039232
1197 1197 a, g dbSNP:749399552
1200 1200 a, g dbSNP:755143850
1201 1201 g, t dbSNP:373472360
1211 1211 a, t dbSNP:779154163
1212 1212 c, t dbSNP:748507767
1215 1215 c, t dbSNP:373454867
1217 1217 c, g dbSNP:747163107
1218 1218 c, g dbSNP:773640359
1243 1243 g, t dbSNP:111296887
1247 1247 c, t dbSNP:139038414
1248 1248 a, g dbSNP:35404413
1253 1253 g, t dbSNP:776235924
1254 1254 c, g dbSNP:759169379
1263 1263 a, g dbSNP:764957102
1276 1276 a, g dbSNP:775344684
1281 1281 a, g dbSNP:762791797
1289 1289 a, g dbSNP:763735177
1290 1290 c, g dbSNP:751371810
1297 1297 a, t dbSNP:757101069
1313 1313 a, g dbSNP:143960265
1331 1331 a, g dbSNP:762449343
1335 1335 c, t dbSNP:763840829
1336 1336 a, c dbSNP:773970722
1348 1348 c, t dbSNP:376677628
1356 1356 c, t dbSNP:767412507
1358 1358 c, t dbSNP:750419153
1359 1359 a, g dbSNP:61755283
1368 1368 a, g dbSNP:769253231
1370 1370 a, g dbSNP:765233671
1373 1373 c, t dbSNP:752851752
1374 1374 a, g dbSNP:758497518
1382 1382 c, t dbSNP:778102032
1384 1384 a, g dbSNP:751836659
1391 1391 -, g dbSNP:140782401
1391 1391 a, t dbSNP:757758557
1394 1394 g, t dbSNP:78810484
1397 1397 -, aggtt dbSNP:758038956
1397 1397 a, g dbSNP:200577481
1400 1400 -, tt dbSNP:780538544
1400 1400 g, t dbSNP:770432581
1401 1401 g, t dbSNP:779393715
1403 1403 a, g dbSNP:748854682
1406 1406 a, g dbSNP:202149829
1411 1411 c, t dbSNP:774093184
1416 1416 a, c dbSNP:369651921
1417 1417 c, g dbSNP:761509086
1420 1420 c, t dbSNP:267603811
1421 1421 a, g, t dbSNP:772994512
1428 1428 a, g dbSNP:766132764
1443 1443 c, t dbSNP:144283302
1446 1446 c, g dbSNP:183736861
1448 1448 a, g dbSNP:763130840
1452 1452 a, c dbSNP:764214378
1464 1464 c, t dbSNP:751861130
1476 1476 a, g dbSNP:757570478
1487 1487 c, g dbSNP:550633524
1503 1503 c, t dbSNP:147834946
1515 1515 a, g dbSNP:750852987
1519 1519 a, g dbSNP:756642822
1526 1526 c, t dbSNP:780662270
1530 1530 a, t dbSNP:150705387
1532 1532 c, t dbSNP:145298804
1546 1546 a, t dbSNP:370143844
1553 1553 c, t dbSNP:755444964
1557 1557 c, t dbSNP:778445360
1560 1560 a, g dbSNP:747678084
1563 1563 a, c dbSNP:758021748
1566 1566 c, t dbSNP:777439738
1567 1567 a, g dbSNP:746799158
1575 1575 c, g, t dbSNP:770814251
1584 1584 c, t dbSNP:150999500
1587 1587 c, t dbSNP:769653656
1599 1599 a, c dbSNP:372575050
1603 1603 c, t dbSNP:373856311
1604 1604 a, g dbSNP:140946240
1608 1608 a, g dbSNP:767819747
1638 1638 a, g dbSNP:773637248
1649 1649 a, t dbSNP:761107193
1661 1661 -, ttc dbSNP:747447718
1662 1662 a, c, t dbSNP:566648386
1667 1667 c, g dbSNP:755462450
1672 1672 a, g dbSNP:61755282
1674 1674 a, c dbSNP:199981149
1700 1700 a, g, t dbSNP:267603812
1701 1701 a, t dbSNP:746602662
1704 1704 a, c, g dbSNP:756868331
1706 1706 a, g dbSNP:745675697
1710 1710 a, g dbSNP:769751473
1713 1713 c, t dbSNP:780183027
1714 1714 a, g dbSNP:748235047
1724 1724 a, g dbSNP:772337527
1733 1733 a, c dbSNP:35918374
1741 1741 a, g dbSNP:749179710
1754 1754 a, g dbSNP:767692772
1774 1774 -, ttc dbSNP:769275091
1783 1783 c, t dbSNP:145699331
1794 1794 a, g dbSNP:180874885
1796 1796 g, t dbSNP:369777099
1797 1797 a, g dbSNP:146743791
1873 1873 a, g dbSNP:770030222
1887 1887 a, c dbSNP:775786587
1889 1889 a, g dbSNP:768461226
1910 1910 c, g dbSNP:140628294
1919 1919 a, g dbSNP:774789693
1925 1925 c, t dbSNP:145685321
1926 1926 a, g dbSNP:565998602
1934 1934 a, t dbSNP:772784183
1937 1937 a, t dbSNP:760364496
1941 1941 c, t dbSNP:138448439
1944 1944 c, t dbSNP:753652601
1945 1945 c, g dbSNP:754886422
1946 1946 a, g dbSNP:765204259
1975 1975 a, g dbSNP:752516162
1978 1978 g, t dbSNP:758356325
1990 1990 c, t dbSNP:759272566
1992 1992 a, g dbSNP:767384520
1998 1998 g, t dbSNP:764871951
1999 1999 a, t dbSNP:374549136
2001 2001 c, t dbSNP:758216737
2002 2002 c, t dbSNP:572634475
2021 2021 -, ttc dbSNP:773213910
2021 2021 c, t dbSNP:750475986
2024 2024 c, t dbSNP:199986257
2031 2031 a, g dbSNP:780245698
2034 2034 a, g dbSNP:375639121
2042 2042 c, t dbSNP:755235455
2047 2047 -, g dbSNP:35916714
2047 2047 c, t dbSNP:750978297
2052 2052 a, g dbSNP:779107107
2059 2059 c, t dbSNP:370199906
2078 2078 c, t dbSNP:772426240
2086 2086 c, t dbSNP:183429673
2095 2095 a, g dbSNP:551830455
2111 2111 c, g dbSNP:576581168
2152 2152 g, t dbSNP:568563514
2228 2228 c, g dbSNP:753848729

Target ORF information:

RefSeq Version XM_011535294
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens cyclin A1 (CCNA1), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011535294

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
ATGCACTGCA GCAACCCCAA GAGTGGAGTT GTGCTGGCTA CAGTGGCCCG AGGTCCCGAT 
GCTTGTCAGA TACTCACCAG AGCCCCGCTG GGCCAGGATC CCCCGCAGAG GACAGTGCTA
GGGCTGCTAA CTGCAAATGG GCAGTACAGG AGGACCTGTG GCCAGGGGAT CACAAGAATC
AGGTGTTATT CTGGATCAGA AAATGCCTTC CCTCCAGCTG GAAAGAAAGC ACTCCCTGAC
TGTGGGGTCC AAGAGCCCCC CAAGCAAGGG TTTGACATCT ACATGGATGA ACTAGAGCAG
GGGGACAGAG ACAGCTGCTC GGTCAGAGAG GGGATGGCAT TTGAGGATGT GTATGAAGTA
GACACCGGCA CACTCAAGTC AGACCTGCAC TTCCTGCTGG ATTTCAACAC AGTTTCCCCT
ATGCTGGTAG ATTCATCTCT CCTCTCCCAG TCTGAAGATA TATCCAGTCT TGGCACAGAT
GTGATAAATG TGACTGAATA TGCTGAAGAA ATTTATCAGT ACCTTAGGGA AGCTGAAATA
AGGCACAGAC CCAAAGCACA CTACATGAAG AAGCAGCCAG ACATCACGGA AGGCATGCGC
ACGATTCTGG TGGACTGGCT GGTGGAGGTT GGGGAAGAAT ATAAACTTCG AGCAGAGACC
CTGTATCTGG CTGTCAACTT CCTGGACAGG TTCCTTTCAT GTATGTCTGT TCTGAGAGGG
AAACTGCAGC TCGTAGGAAC AGCAGCTATG CTTTTGGCTT CGAAATATGA AGAGATATAT
CCTCCTGAAG TAGACGAGTT TGTCTATATC ACCGATGATA CATACACAAA ACGACAACTG
TTAAAAATGG AACACTTGCT TCTGAAAGTT CTAGCTTTTG ATCTGACAGT ACCAACCACC
AACCAGTTTC TCCTTCAGTA CTTGAGGCGA CAAGGAGTGT GCGTCAGGAC TGAGAACCTG
GCTAAGTACG TAGCAGAGCT GAGTCTACTT GAAGCAGATC CATTCTTGAA ATATCTTCCT
TCACTGATAG CTGCAGCAGC TTTTTGCCTG GCAAACTATA CTGTGAACAA GCACTTTTGG
CCAGAAACCC TTGCTGCATT TACAGGGTAT TCATTAAGTG AAATTGTGCC TTGCCTGAGT
GAGCTTCATA AAGCGTACCT TGATATACCC CATCGACCTC AGCAAGCAAT TAGGGAGAAG
TACAAGGCTT CAAAGTACCT GTGTGTGTCC CTCATGGAGC CACCTGCAGT TCTTCTTCTA
CAATAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu25352
Accession Version XM_011535295.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1266bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product cyclin-A1 isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_024524.15) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
ATGCACTGCA GCAACCCCAA GAGTGGAGTT GTGCTGGCTA CAGTGGCCCG AGGTCCCGAT 
GCTTGTCAGA TACTCACCAG AGCCCCGCTG GGCCAGGATC CCCCGCAGAG GACAGTGCTA
GGGCTGCTAA CTGCAAATGG GCAGTACAGG AGGACCTGTG GCCAGGGGAT CACAAGAATC
AGGTGTTATT CTGGATCAGA AAATGCCTTC CCTCCAGCTG GAAAGAAAGC ACTCCCTGAC
TGTGGGGTCC AAGAGCCCCC CAAGCAAGGG TTTGACATCT ACATGGATGA ACTAGAGCAG
GGGGACAGAG ACAGCTGCTC GGTCAGAGAG GGGATGGCAT TTGAGGATGT GTATGAAGTA
GACACCGGCA CACTCAAGTC AGACCTGCAC TTCCTGCTGG ATTTCAACAC AGTTTCCCCT
ATGCTGGTAG ATTCATCTCT CCTCTCCCAG TCTGAAGATA TATCCAGTCT TGGCACAGAT
GTGATAAATG TGACTGAATA TGCTGAAGAA ATTTATCAGT ACCTTAGGGA AGCTGAAATA
AGGCACAGAC CCAAAGCACA CTACATGAAG AAGCAGCCAG ACATCACGGA AGGCATGCGC
ACGATTCTGG TGGACTGGCT GGTGGAGGTT GGGGAAGAAT ATAAACTTCG AGCAGAGACC
CTGTATCTGG CTGTCAACTT CCTGGACAGG TTCCTTTCAT GTATGTCTGT TCTGAGAGGG
AAACTGCAGC TCGTAGGAAC AGCAGCTATG CTTTTGGCTT CGAAATATGA AGAGATATAT
CCTCCTGAAG TAGACGAGTT TGTCTATATC ACCGATGATA CATACACAAA ACGACAACTG
TTAAAAATGG AACACTTGCT TCTGAAAGTT CTAGCTTTTG ATCTGACAGT ACCAACCACC
AACCAGTTTC TCCTTCAGTA CTTGAGGCGA CAAGGAGTGT GCGTCAGGAC TGAGAACCTG
GCTAAGTACG TAGCAGAGCT GAGTCTACTT GAAGCAGATC CATTCTTGAA ATATCTTCCT
TCACTGATAG CTGCAGCAGC TTTTTGCCTG GCAAACTATA CTGTGAACAA GCACTTTTGG
CCAGAAACCC TTGCTGCATT TACAGGGTAT TCATTAAGTG AAATTGTGCC TTGCCTGAGT
GAGCTTCATA AAGCGTACCT TGATATACCC CATCGACCTC AGCAAGCAAT TAGGGAGAAG
TACAAGGCTT CAAAGTACCT GTGTGTGTCC CTCATGGAGC CACCTGCAGT TCTTCTTCTA
CAATAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeqXP_011533597.1
CDS769..2034
Misc Feature(1)1363..1632(+)
Misc Feature(2)1363..1497(+)
Misc Feature(3)1519..1620(+)
Misc Feature(4)1654..1917(+)
Misc Feature(5)1654..1791(+)
Misc Feature(6)1813..1905(+)
Translation
Position Chain Variation Link
14 14 c, g dbSNP:79637235
35 35 g, t dbSNP:545995822
44 44 a, c dbSNP:115732208
73 73 c, g dbSNP:563774417
77 77 a, c dbSNP:116168763
78 78 c, t dbSNP:549132723
105 105 a, g dbSNP:772739621
107 107 c, g dbSNP:149008909
124 124 g, t dbSNP:3829944
143 143 a, g dbSNP:776794197
149 149 c, t dbSNP:546916173
193 193 c, t dbSNP:571109466
202 202 a, t dbSNP:538451419
227 227 -, ta dbSNP:555180235
231 231 -, a dbSNP:760771229
243 243 a, g dbSNP:760014241
271 271 a, t dbSNP:112307354
272 272 a, t dbSNP:568624584
285 285 g, t dbSNP:548540595
319 319 c, t dbSNP:554242865
346 346 a, g dbSNP:572828672
363 363 a, c dbSNP:534996997
442 442 a, c dbSNP:115056545
469 469 a, c dbSNP:578182289
480 480 c, t dbSNP:545634068
488 488 a, g dbSNP:775833724
495 495 g, t dbSNP:760198443
535 535 g, t dbSNP:557464962
563 563 c, g dbSNP:575627370
573 573 c, g dbSNP:3829943
587 587 a, t dbSNP:561118523
590 590 c, g dbSNP:528536753
624 624 a, g dbSNP:753367685
639 639 c, g dbSNP:540091397
643 643 c, g dbSNP:541143574
659 659 -, a dbSNP:35326131
667 667 a, c dbSNP:376841838
683 683 a, c dbSNP:532138212
684 684 a, c dbSNP:373607677
703 703 a, g dbSNP:550380815
733 733 c, t dbSNP:569058337
750 750 c, g dbSNP:141476503
759 759 a, g dbSNP:755391943
768 768 a, g dbSNP:779524233
774 774 c, t dbSNP:147007878
777 777 -, cagcaa dbSNP:763106197
780 780 c, g, t dbSNP:377589059
785 785 c, t dbSNP:142133640
786 786 c, t dbSNP:151081377
789 789 a, g dbSNP:746609003
791 791 a, g dbSNP:145220476
797 797 c, t dbSNP:560118670
808 808 a, g dbSNP:370964964
810 810 a, g dbSNP:759393578
814 814 a, g dbSNP:769594081
825 825 c, t dbSNP:149125997
830 830 c, t dbSNP:761793251
834 834 c, t dbSNP:767691805
838 838 a, t dbSNP:368007173
847 847 a, g dbSNP:143296005
853 853 c, g dbSNP:370590641
854 854 c, g dbSNP:760912284
862 862 c, t dbSNP:766731424
863 863 a, g dbSNP:754232617
864 864 c, g dbSNP:540233147
868 868 c, g, t dbSNP:552343736
871 871 c, t dbSNP:753307734
872 872 a, c dbSNP:746200537
873 873 a, g dbSNP:758844418
879 879 a, g dbSNP:201226091
885 885 a, g dbSNP:148316727
907 907 a, g dbSNP:746557549
944 944 a, g dbSNP:751042420
946 946 a, g dbSNP:756797263
948 948 c, g dbSNP:780816141
949 949 a, t dbSNP:575517029
951 951 a, g dbSNP:772777206
954 954 c, t dbSNP:779831451
957 957 c, t dbSNP:61729896
982 982 c, t dbSNP:768692826
983 983 c, t dbSNP:774471192
986 986 c, g, t dbSNP:747082248
999 999 a, g dbSNP:145829125
1014 1014 a, g dbSNP:759740467
1015 1015 g, t dbSNP:765412925
1017 1017 a, c dbSNP:775879131
1018 1018 c, g dbSNP:763352839
1023 1023 -, c dbSNP:777748261
1023 1023 a, g dbSNP:764550152
1024 1024 c, g, t dbSNP:574280988
1025 1025 c, g dbSNP:367588569
1026 1026 a, c dbSNP:749904346
1028 1028 c, g dbSNP:755751093
1038 1038 a, g, t dbSNP:779594513
1051 1051 a, g dbSNP:754888442
1061 1061 a, t dbSNP:61733784
1069 1069 a, g dbSNP:371431411
1072 1072 g, t dbSNP:748042719
1080 1080 c, t dbSNP:772143355
1088 1088 c, t dbSNP:143100244
1089 1089 a, g, t dbSNP:368505689
1091 1091 c, t dbSNP:765937307
1093 1093 -, ag dbSNP:753784627
1094 1094 a, g dbSNP:540179877
1099 1099 a, g dbSNP:763296052
1100 1100 g, t dbSNP:769065045
1103 1103 c, t dbSNP:113260257
1111 1111 a, g dbSNP:199835821
1118 1118 a, t dbSNP:374907767
1119 1119 a, g dbSNP:767940034
1125 1125 a, g dbSNP:753412232
1128 1128 a, g dbSNP:760144028
1134 1134 c, t dbSNP:766051820
1135 1135 a, g dbSNP:753604464
1141 1141 c, t dbSNP:754694176
1144 1144 a, g dbSNP:368185225
1152 1152 c, t dbSNP:201364984
1155 1155 a, g dbSNP:758365529
1157 1157 a, g dbSNP:777624140
1175 1175 a, g dbSNP:200724447
1176 1176 c, t dbSNP:769827681
1177 1177 a, g dbSNP:780306675
1179 1179 a, g dbSNP:749452494
1184 1184 c, t dbSNP:778026294
1189 1189 a, g dbSNP:757229441
1193 1193 c, t dbSNP:780039232
1194 1194 a, g dbSNP:749399552
1197 1197 a, g dbSNP:755143850
1198 1198 g, t dbSNP:373472360
1208 1208 a, t dbSNP:779154163
1209 1209 c, t dbSNP:748507767
1212 1212 c, t dbSNP:373454867
1214 1214 c, g dbSNP:747163107
1215 1215 c, g dbSNP:773640359
1240 1240 g, t dbSNP:111296887
1244 1244 c, t dbSNP:139038414
1245 1245 a, g dbSNP:35404413
1250 1250 g, t dbSNP:776235924
1251 1251 c, g dbSNP:759169379
1260 1260 a, g dbSNP:764957102
1273 1273 a, g dbSNP:775344684
1278 1278 a, g dbSNP:762791797
1286 1286 a, g dbSNP:763735177
1287 1287 c, g dbSNP:751371810
1294 1294 a, t dbSNP:757101069
1310 1310 a, g dbSNP:143960265
1328 1328 a, g dbSNP:762449343
1332 1332 c, t dbSNP:763840829
1333 1333 a, c dbSNP:773970722
1345 1345 c, t dbSNP:376677628
1353 1353 c, t dbSNP:767412507
1355 1355 c, t dbSNP:750419153
1356 1356 a, g dbSNP:61755283
1365 1365 a, g dbSNP:769253231
1367 1367 a, g dbSNP:765233671
1370 1370 c, t dbSNP:752851752
1371 1371 a, g dbSNP:758497518
1379 1379 c, t dbSNP:778102032
1381 1381 a, g dbSNP:751836659
1388 1388 -, g dbSNP:140782401
1388 1388 a, t dbSNP:757758557
1391 1391 g, t dbSNP:78810484
1394 1394 -, aggtt dbSNP:758038956
1394 1394 a, g dbSNP:200577481
1397 1397 -, tt dbSNP:780538544
1397 1397 g, t dbSNP:770432581
1398 1398 g, t dbSNP:779393715
1400 1400 a, g dbSNP:748854682
1403 1403 a, g dbSNP:202149829
1408 1408 c, t dbSNP:774093184
1413 1413 a, c dbSNP:369651921
1414 1414 c, g dbSNP:761509086
1417 1417 c, t dbSNP:267603811
1418 1418 a, g, t dbSNP:772994512
1425 1425 a, g dbSNP:766132764
1440 1440 c, t dbSNP:144283302
1443 1443 c, g dbSNP:183736861
1445 1445 a, g dbSNP:763130840
1449 1449 a, c dbSNP:764214378
1461 1461 c, t dbSNP:751861130
1473 1473 a, g dbSNP:757570478
1484 1484 c, g dbSNP:550633524
1500 1500 c, t dbSNP:147834946
1512 1512 a, g dbSNP:750852987
1516 1516 a, g dbSNP:756642822
1523 1523 c, t dbSNP:780662270
1527 1527 a, t dbSNP:150705387
1529 1529 c, t dbSNP:145298804
1543 1543 a, t dbSNP:370143844
1550 1550 c, t dbSNP:755444964
1554 1554 c, t dbSNP:778445360
1557 1557 a, g dbSNP:747678084
1560 1560 a, c dbSNP:758021748
1563 1563 c, t dbSNP:777439738
1564 1564 a, g dbSNP:746799158
1572 1572 c, g, t dbSNP:770814251
1581 1581 c, t dbSNP:150999500
1584 1584 c, t dbSNP:769653656
1596 1596 a, c dbSNP:372575050
1600 1600 c, t dbSNP:373856311
1601 1601 a, g dbSNP:140946240
1605 1605 a, g dbSNP:767819747
1635 1635 a, g dbSNP:773637248
1646 1646 a, t dbSNP:761107193
1658 1658 -, ttc dbSNP:747447718
1659 1659 a, c, t dbSNP:566648386
1664 1664 c, g dbSNP:755462450
1669 1669 a, g dbSNP:61755282
1671 1671 a, c dbSNP:199981149
1697 1697 a, g, t dbSNP:267603812
1698 1698 a, t dbSNP:746602662
1701 1701 a, c, g dbSNP:756868331
1703 1703 a, g dbSNP:745675697
1707 1707 a, g dbSNP:769751473
1710 1710 c, t dbSNP:780183027
1711 1711 a, g dbSNP:748235047
1721 1721 a, g dbSNP:772337527
1730 1730 a, c dbSNP:35918374
1738 1738 a, g dbSNP:749179710
1751 1751 a, g dbSNP:767692772
1771 1771 -, ttc dbSNP:769275091
1780 1780 c, t dbSNP:145699331
1791 1791 a, g dbSNP:180874885
1793 1793 g, t dbSNP:369777099
1794 1794 a, g dbSNP:146743791
1870 1870 a, g dbSNP:770030222
1884 1884 a, c dbSNP:775786587
1886 1886 a, g dbSNP:768461226
1907 1907 c, g dbSNP:140628294
1916 1916 a, g dbSNP:774789693
1922 1922 c, t dbSNP:145685321
1923 1923 a, g dbSNP:565998602
1931 1931 a, t dbSNP:772784183
1934 1934 a, t dbSNP:760364496
1938 1938 c, t dbSNP:138448439
1941 1941 c, t dbSNP:753652601
1942 1942 c, g dbSNP:754886422
1943 1943 a, g dbSNP:765204259
1972 1972 a, g dbSNP:752516162
1975 1975 g, t dbSNP:758356325
1987 1987 c, t dbSNP:759272566
1989 1989 a, g dbSNP:767384520
1995 1995 g, t dbSNP:764871951
1996 1996 a, t dbSNP:374549136
1998 1998 c, t dbSNP:758216737
1999 1999 c, t dbSNP:572634475
2018 2018 -, ttc dbSNP:773213910
2018 2018 c, t dbSNP:750475986
2021 2021 c, t dbSNP:199986257
2028 2028 a, g dbSNP:780245698
2031 2031 a, g dbSNP:375639121
2039 2039 c, t dbSNP:755235455
2044 2044 -, g dbSNP:35916714
2044 2044 c, t dbSNP:750978297
2049 2049 a, g dbSNP:779107107
2056 2056 c, t dbSNP:370199906
2075 2075 c, t dbSNP:772426240
2083 2083 c, t dbSNP:183429673
2092 2092 a, g dbSNP:551830455
2108 2108 c, g dbSNP:576581168
2149 2149 g, t dbSNP:568563514
2225 2225 c, g dbSNP:753848729

Target ORF information:

RefSeq Version XM_011535295
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens cyclin A1 (CCNA1), transcript variant X2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011535295

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
ATGCACTGCA GCAACCCCAA GAGTGGAGTT GTGCTGGCTA CAGTGGCCCG AGGTCCCGAT 
GCTTGTCAGA TACTCACCAG AGCCCCGCTG GGCCAGGATC CCCCGCAGAG GACAGTGCTA
GGGCTGCTAA CTGCAAATGG GCAGTACAGG AGGACCTGTG GCCAGGGGAT CACAAGAATC
AGGTGTTATT CTGGATCAGA AAATGCCTTC CCTCCAGCTG GAAAGAAAGC ACTCCCTGAC
TGTGGGGTCC AAGAGCCCCC CAAGCAAGGG TTTGACATCT ACATGGATGA ACTAGAGCAG
GGGGACAGAG ACAGCTGCTC GGTCAGAGAG GGGATGGCAT TTGAGGATGT GTATGAAGTA
GACACCGGCA CACTCAAGTC AGACCTGCAC TTCCTGCTGG ATTTCAACAC AGTTTCCCCT
ATGCTGGTAG ATTCATCTCT CCTCTCCCAG TCTGAAGATA TATCCAGTCT TGGCACAGAT
GTGATAAATG TGACTGAATA TGCTGAAGAA ATTTATCAGT ACCTTAGGGA AGCTGAAATA
AGGCACAGAC CCAAAGCACA CTACATGAAG AAGCAGCCAG ACATCACGGA AGGCATGCGC
ACGATTCTGG TGGACTGGCT GGTGGAGGTT GGGGAAGAAT ATAAACTTCG AGCAGAGACC
CTGTATCTGG CTGTCAACTT CCTGGACAGG TTCCTTTCAT GTATGTCTGT TCTGAGAGGG
AAACTGCAGC TCGTAGGAAC AGCAGCTATG CTTTTGGCTT CGAAATATGA AGAGATATAT
CCTCCTGAAG TAGACGAGTT TGTCTATATC ACCGATGATA CATACACAAA ACGACAACTG
TTAAAAATGG AACACTTGCT TCTGAAAGTT CTAGCTTTTG ATCTGACAGT ACCAACCACC
AACCAGTTTC TCCTTCAGTA CTTGAGGCGA CAAGGAGTGT GCGTCAGGAC TGAGAACCTG
GCTAAGTACG TAGCAGAGCT GAGTCTACTT GAAGCAGATC CATTCTTGAA ATATCTTCCT
TCACTGATAG CTGCAGCAGC TTTTTGCCTG GCAAACTATA CTGTGAACAA GCACTTTTGG
CCAGAAACCC TTGCTGCATT TACAGGGTAT TCATTAAGTG AAATTGTGCC TTGCCTGAGT
GAGCTTCATA AAGCGTACCT TGATATACCC CATCGACCTC AGCAAGCAAT TAGGGAGAAG
TACAAGGCTT CAAAGTACCT GTGTGTGTCC CTCATGGAGC CACCTGCAGT TCTTCTTCTA
CAATAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu25352
Accession Version XM_011535296.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1266bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product cyclin-A1 isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_024524.15) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
ATGCACTGCA GCAACCCCAA GAGTGGAGTT GTGCTGGCTA CAGTGGCCCG AGGTCCCGAT 
GCTTGTCAGA TACTCACCAG AGCCCCGCTG GGCCAGGATC CCCCGCAGAG GACAGTGCTA
GGGCTGCTAA CTGCAAATGG GCAGTACAGG AGGACCTGTG GCCAGGGGAT CACAAGAATC
AGGTGTTATT CTGGATCAGA AAATGCCTTC CCTCCAGCTG GAAAGAAAGC ACTCCCTGAC
TGTGGGGTCC AAGAGCCCCC CAAGCAAGGG TTTGACATCT ACATGGATGA ACTAGAGCAG
GGGGACAGAG ACAGCTGCTC GGTCAGAGAG GGGATGGCAT TTGAGGATGT GTATGAAGTA
GACACCGGCA CACTCAAGTC AGACCTGCAC TTCCTGCTGG ATTTCAACAC AGTTTCCCCT
ATGCTGGTAG ATTCATCTCT CCTCTCCCAG TCTGAAGATA TATCCAGTCT TGGCACAGAT
GTGATAAATG TGACTGAATA TGCTGAAGAA ATTTATCAGT ACCTTAGGGA AGCTGAAATA
AGGCACAGAC CCAAAGCACA CTACATGAAG AAGCAGCCAG ACATCACGGA AGGCATGCGC
ACGATTCTGG TGGACTGGCT GGTGGAGGTT GGGGAAGAAT ATAAACTTCG AGCAGAGACC
CTGTATCTGG CTGTCAACTT CCTGGACAGG TTCCTTTCAT GTATGTCTGT TCTGAGAGGG
AAACTGCAGC TCGTAGGAAC AGCAGCTATG CTTTTGGCTT CGAAATATGA AGAGATATAT
CCTCCTGAAG TAGACGAGTT TGTCTATATC ACCGATGATA CATACACAAA ACGACAACTG
TTAAAAATGG AACACTTGCT TCTGAAAGTT CTAGCTTTTG ATCTGACAGT ACCAACCACC
AACCAGTTTC TCCTTCAGTA CTTGAGGCGA CAAGGAGTGT GCGTCAGGAC TGAGAACCTG
GCTAAGTACG TAGCAGAGCT GAGTCTACTT GAAGCAGATC CATTCTTGAA ATATCTTCCT
TCACTGATAG CTGCAGCAGC TTTTTGCCTG GCAAACTATA CTGTGAACAA GCACTTTTGG
CCAGAAACCC TTGCTGCATT TACAGGGTAT TCATTAAGTG AAATTGTGCC TTGCCTGAGT
GAGCTTCATA AAGCGTACCT TGATATACCC CATCGACCTC AGCAAGCAAT TAGGGAGAAG
TACAAGGCTT CAAAGTACCT GTGTGTGTCC CTCATGGAGC CACCTGCAGT TCTTCTTCTA
CAATAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeqXP_011533598.1
CDS136..1401
Misc Feature(1)730..999(+)
Misc Feature(2)730..864(+)
Misc Feature(3)886..987(+)
Misc Feature(4)1021..1284(+)
Misc Feature(5)1021..1158(+)
Misc Feature(6)1180..1272(+)
Translation
Position Chain Variation Link
4 4 g, t dbSNP:11839265
34 34 g, t dbSNP:544131704
37 37 a, c dbSNP:562532073
44 44 g, t dbSNP:529946723
66 66 c, t dbSNP:547930716
117 117 c, g dbSNP:141476503
126 126 a, g dbSNP:755391943
135 135 a, g dbSNP:779524233
141 141 c, t dbSNP:147007878
144 144 -, cagcaa dbSNP:763106197
147 147 c, g, t dbSNP:377589059
152 152 c, t dbSNP:142133640
153 153 c, t dbSNP:151081377
156 156 a, g dbSNP:746609003
158 158 a, g dbSNP:145220476
164 164 c, t dbSNP:560118670
175 175 a, g dbSNP:370964964
177 177 a, g dbSNP:759393578
181 181 a, g dbSNP:769594081
192 192 c, t dbSNP:149125997
197 197 c, t dbSNP:761793251
201 201 c, t dbSNP:767691805
205 205 a, t dbSNP:368007173
214 214 a, g dbSNP:143296005
220 220 c, g dbSNP:370590641
221 221 c, g dbSNP:760912284
229 229 c, t dbSNP:766731424
230 230 a, g dbSNP:754232617
231 231 c, g dbSNP:540233147
235 235 c, g, t dbSNP:552343736
238 238 c, t dbSNP:753307734
239 239 a, c dbSNP:746200537
240 240 a, g dbSNP:758844418
246 246 a, g dbSNP:201226091
252 252 a, g dbSNP:148316727
274 274 a, g dbSNP:746557549
311 311 a, g dbSNP:751042420
313 313 a, g dbSNP:756797263
315 315 c, g dbSNP:780816141
316 316 a, t dbSNP:575517029
318 318 a, g dbSNP:772777206
321 321 c, t dbSNP:779831451
324 324 c, t dbSNP:61729896
349 349 c, t dbSNP:768692826
350 350 c, t dbSNP:774471192
353 353 c, g, t dbSNP:747082248
366 366 a, g dbSNP:145829125
381 381 a, g dbSNP:759740467
382 382 g, t dbSNP:765412925
384 384 a, c dbSNP:775879131
385 385 c, g dbSNP:763352839
390 390 -, c dbSNP:777748261
390 390 a, g dbSNP:764550152
391 391 c, g, t dbSNP:574280988
392 392 c, g dbSNP:367588569
393 393 a, c dbSNP:749904346
395 395 c, g dbSNP:755751093
405 405 a, g, t dbSNP:779594513
418 418 a, g dbSNP:754888442
428 428 a, t dbSNP:61733784
436 436 a, g dbSNP:371431411
439 439 g, t dbSNP:748042719
447 447 c, t dbSNP:772143355
455 455 c, t dbSNP:143100244
456 456 a, g, t dbSNP:368505689
458 458 c, t dbSNP:765937307
460 460 -, ag dbSNP:753784627
461 461 a, g dbSNP:540179877
466 466 a, g dbSNP:763296052
467 467 g, t dbSNP:769065045
470 470 c, t dbSNP:113260257
478 478 a, g dbSNP:199835821
485 485 a, t dbSNP:374907767
486 486 a, g dbSNP:767940034
492 492 a, g dbSNP:753412232
495 495 a, g dbSNP:760144028
501 501 c, t dbSNP:766051820
502 502 a, g dbSNP:753604464
508 508 c, t dbSNP:754694176
511 511 a, g dbSNP:368185225
519 519 c, t dbSNP:201364984
522 522 a, g dbSNP:758365529
524 524 a, g dbSNP:777624140
542 542 a, g dbSNP:200724447
543 543 c, t dbSNP:769827681
544 544 a, g dbSNP:780306675
546 546 a, g dbSNP:749452494
551 551 c, t dbSNP:778026294
556 556 a, g dbSNP:757229441
560 560 c, t dbSNP:780039232
561 561 a, g dbSNP:749399552
564 564 a, g dbSNP:755143850
565 565 g, t dbSNP:373472360
575 575 a, t dbSNP:779154163
576 576 c, t dbSNP:748507767
579 579 c, t dbSNP:373454867
581 581 c, g dbSNP:747163107
582 582 c, g dbSNP:773640359
607 607 g, t dbSNP:111296887
611 611 c, t dbSNP:139038414
612 612 a, g dbSNP:35404413
617 617 g, t dbSNP:776235924
618 618 c, g dbSNP:759169379
627 627 a, g dbSNP:764957102
640 640 a, g dbSNP:775344684
645 645 a, g dbSNP:762791797
653 653 a, g dbSNP:763735177
654 654 c, g dbSNP:751371810
661 661 a, t dbSNP:757101069
677 677 a, g dbSNP:143960265
695 695 a, g dbSNP:762449343
699 699 c, t dbSNP:763840829
700 700 a, c dbSNP:773970722
712 712 c, t dbSNP:376677628
720 720 c, t dbSNP:767412507
722 722 c, t dbSNP:750419153
723 723 a, g dbSNP:61755283
732 732 a, g dbSNP:769253231
734 734 a, g dbSNP:765233671
737 737 c, t dbSNP:752851752
738 738 a, g dbSNP:758497518
746 746 c, t dbSNP:778102032
748 748 a, g dbSNP:751836659
755 755 -, g dbSNP:140782401
755 755 a, t dbSNP:757758557
758 758 g, t dbSNP:78810484
761 761 -, aggtt dbSNP:758038956
761 761 a, g dbSNP:200577481
764 764 -, tt dbSNP:780538544
764 764 g, t dbSNP:770432581
765 765 g, t dbSNP:779393715
767 767 a, g dbSNP:748854682
770 770 a, g dbSNP:202149829
775 775 c, t dbSNP:774093184
780 780 a, c dbSNP:369651921
781 781 c, g dbSNP:761509086
784 784 c, t dbSNP:267603811
785 785 a, g, t dbSNP:772994512
792 792 a, g dbSNP:766132764
807 807 c, t dbSNP:144283302
810 810 c, g dbSNP:183736861
812 812 a, g dbSNP:763130840
816 816 a, c dbSNP:764214378
828 828 c, t dbSNP:751861130
840 840 a, g dbSNP:757570478
851 851 c, g dbSNP:550633524
867 867 c, t dbSNP:147834946
879 879 a, g dbSNP:750852987
883 883 a, g dbSNP:756642822
890 890 c, t dbSNP:780662270
894 894 a, t dbSNP:150705387
896 896 c, t dbSNP:145298804
910 910 a, t dbSNP:370143844
917 917 c, t dbSNP:755444964
921 921 c, t dbSNP:778445360
924 924 a, g dbSNP:747678084
927 927 a, c dbSNP:758021748
930 930 c, t dbSNP:777439738
931 931 a, g dbSNP:746799158
939 939 c, g, t dbSNP:770814251
948 948 c, t dbSNP:150999500
951 951 c, t dbSNP:769653656
963 963 a, c dbSNP:372575050
967 967 c, t dbSNP:373856311
968 968 a, g dbSNP:140946240
972 972 a, g dbSNP:767819747
1002 1002 a, g dbSNP:773637248
1013 1013 a, t dbSNP:761107193
1025 1025 -, ttc dbSNP:747447718
1026 1026 a, c, t dbSNP:566648386
1031 1031 c, g dbSNP:755462450
1036 1036 a, g dbSNP:61755282
1038 1038 a, c dbSNP:199981149
1064 1064 a, g, t dbSNP:267603812
1065 1065 a, t dbSNP:746602662
1068 1068 a, c, g dbSNP:756868331
1070 1070 a, g dbSNP:745675697
1074 1074 a, g dbSNP:769751473
1077 1077 c, t dbSNP:780183027
1078 1078 a, g dbSNP:748235047
1088 1088 a, g dbSNP:772337527
1097 1097 a, c dbSNP:35918374
1105 1105 a, g dbSNP:749179710
1118 1118 a, g dbSNP:767692772
1138 1138 -, ttc dbSNP:769275091
1147 1147 c, t dbSNP:145699331
1158 1158 a, g dbSNP:180874885
1160 1160 g, t dbSNP:369777099
1161 1161 a, g dbSNP:146743791
1237 1237 a, g dbSNP:770030222
1251 1251 a, c dbSNP:775786587
1253 1253 a, g dbSNP:768461226
1274 1274 c, g dbSNP:140628294
1283 1283 a, g dbSNP:774789693
1289 1289 c, t dbSNP:145685321
1290 1290 a, g dbSNP:565998602
1298 1298 a, t dbSNP:772784183
1301 1301 a, t dbSNP:760364496
1305 1305 c, t dbSNP:138448439
1308 1308 c, t dbSNP:753652601
1309 1309 c, g dbSNP:754886422
1310 1310 a, g dbSNP:765204259
1339 1339 a, g dbSNP:752516162
1342 1342 g, t dbSNP:758356325
1354 1354 c, t dbSNP:759272566
1356 1356 a, g dbSNP:767384520
1362 1362 g, t dbSNP:764871951
1363 1363 a, t dbSNP:374549136
1365 1365 c, t dbSNP:758216737
1366 1366 c, t dbSNP:572634475
1385 1385 -, ttc dbSNP:773213910
1385 1385 c, t dbSNP:750475986
1388 1388 c, t dbSNP:199986257
1395 1395 a, g dbSNP:780245698
1398 1398 a, g dbSNP:375639121
1406 1406 c, t dbSNP:755235455
1411 1411 -, g dbSNP:35916714
1411 1411 c, t dbSNP:750978297
1416 1416 a, g dbSNP:779107107
1423 1423 c, t dbSNP:370199906
1442 1442 c, t dbSNP:772426240
1450 1450 c, t dbSNP:183429673
1459 1459 a, g dbSNP:551830455
1475 1475 c, g dbSNP:576581168
1516 1516 g, t dbSNP:568563514
1592 1592 c, g dbSNP:753848729

Target ORF information:

RefSeq Version XM_011535296
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens cyclin A1 (CCNA1), transcript variant X3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011535296

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
ATGCACTGCA GCAACCCCAA GAGTGGAGTT GTGCTGGCTA CAGTGGCCCG AGGTCCCGAT 
GCTTGTCAGA TACTCACCAG AGCCCCGCTG GGCCAGGATC CCCCGCAGAG GACAGTGCTA
GGGCTGCTAA CTGCAAATGG GCAGTACAGG AGGACCTGTG GCCAGGGGAT CACAAGAATC
AGGTGTTATT CTGGATCAGA AAATGCCTTC CCTCCAGCTG GAAAGAAAGC ACTCCCTGAC
TGTGGGGTCC AAGAGCCCCC CAAGCAAGGG TTTGACATCT ACATGGATGA ACTAGAGCAG
GGGGACAGAG ACAGCTGCTC GGTCAGAGAG GGGATGGCAT TTGAGGATGT GTATGAAGTA
GACACCGGCA CACTCAAGTC AGACCTGCAC TTCCTGCTGG ATTTCAACAC AGTTTCCCCT
ATGCTGGTAG ATTCATCTCT CCTCTCCCAG TCTGAAGATA TATCCAGTCT TGGCACAGAT
GTGATAAATG TGACTGAATA TGCTGAAGAA ATTTATCAGT ACCTTAGGGA AGCTGAAATA
AGGCACAGAC CCAAAGCACA CTACATGAAG AAGCAGCCAG ACATCACGGA AGGCATGCGC
ACGATTCTGG TGGACTGGCT GGTGGAGGTT GGGGAAGAAT ATAAACTTCG AGCAGAGACC
CTGTATCTGG CTGTCAACTT CCTGGACAGG TTCCTTTCAT GTATGTCTGT TCTGAGAGGG
AAACTGCAGC TCGTAGGAAC AGCAGCTATG CTTTTGGCTT CGAAATATGA AGAGATATAT
CCTCCTGAAG TAGACGAGTT TGTCTATATC ACCGATGATA CATACACAAA ACGACAACTG
TTAAAAATGG AACACTTGCT TCTGAAAGTT CTAGCTTTTG ATCTGACAGT ACCAACCACC
AACCAGTTTC TCCTTCAGTA CTTGAGGCGA CAAGGAGTGT GCGTCAGGAC TGAGAACCTG
GCTAAGTACG TAGCAGAGCT GAGTCTACTT GAAGCAGATC CATTCTTGAA ATATCTTCCT
TCACTGATAG CTGCAGCAGC TTTTTGCCTG GCAAACTATA CTGTGAACAA GCACTTTTGG
CCAGAAACCC TTGCTGCATT TACAGGGTAT TCATTAAGTG AAATTGTGCC TTGCCTGAGT
GAGCTTCATA AAGCGTACCT TGATATACCC CATCGACCTC AGCAAGCAAT TAGGGAGAAG
TACAAGGCTT CAAAGTACCT GTGTGTGTCC CTCATGGAGC CACCTGCAGT TCTTCTTCTA
CAATAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu25352
Accession Version XM_011535297.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1266bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product cyclin-A1 isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_024524.15) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
ATGCACTGCA GCAACCCCAA GAGTGGAGTT GTGCTGGCTA CAGTGGCCCG AGGTCCCGAT 
GCTTGTCAGA TACTCACCAG AGCCCCGCTG GGCCAGGATC CCCCGCAGAG GACAGTGCTA
GGGCTGCTAA CTGCAAATGG GCAGTACAGG AGGACCTGTG GCCAGGGGAT CACAAGAATC
AGGTGTTATT CTGGATCAGA AAATGCCTTC CCTCCAGCTG GAAAGAAAGC ACTCCCTGAC
TGTGGGGTCC AAGAGCCCCC CAAGCAAGGG TTTGACATCT ACATGGATGA ACTAGAGCAG
GGGGACAGAG ACAGCTGCTC GGTCAGAGAG GGGATGGCAT TTGAGGATGT GTATGAAGTA
GACACCGGCA CACTCAAGTC AGACCTGCAC TTCCTGCTGG ATTTCAACAC AGTTTCCCCT
ATGCTGGTAG ATTCATCTCT CCTCTCCCAG TCTGAAGATA TATCCAGTCT TGGCACAGAT
GTGATAAATG TGACTGAATA TGCTGAAGAA ATTTATCAGT ACCTTAGGGA AGCTGAAATA
AGGCACAGAC CCAAAGCACA CTACATGAAG AAGCAGCCAG ACATCACGGA AGGCATGCGC
ACGATTCTGG TGGACTGGCT GGTGGAGGTT GGGGAAGAAT ATAAACTTCG AGCAGAGACC
CTGTATCTGG CTGTCAACTT CCTGGACAGG TTCCTTTCAT GTATGTCTGT TCTGAGAGGG
AAACTGCAGC TCGTAGGAAC AGCAGCTATG CTTTTGGCTT CGAAATATGA AGAGATATAT
CCTCCTGAAG TAGACGAGTT TGTCTATATC ACCGATGATA CATACACAAA ACGACAACTG
TTAAAAATGG AACACTTGCT TCTGAAAGTT CTAGCTTTTG ATCTGACAGT ACCAACCACC
AACCAGTTTC TCCTTCAGTA CTTGAGGCGA CAAGGAGTGT GCGTCAGGAC TGAGAACCTG
GCTAAGTACG TAGCAGAGCT GAGTCTACTT GAAGCAGATC CATTCTTGAA ATATCTTCCT
TCACTGATAG CTGCAGCAGC TTTTTGCCTG GCAAACTATA CTGTGAACAA GCACTTTTGG
CCAGAAACCC TTGCTGCATT TACAGGGTAT TCATTAAGTG AAATTGTGCC TTGCCTGAGT
GAGCTTCATA AAGCGTACCT TGATATACCC CATCGACCTC AGCAAGCAAT TAGGGAGAAG
TACAAGGCTT CAAAGTACCT GTGTGTGTCC CTCATGGAGC CACCTGCAGT TCTTCTTCTA
CAATAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeqXP_011533599.1
CDS139..1404
Misc Feature(1)733..1002(+)
Misc Feature(2)733..867(+)
Misc Feature(3)889..990(+)
Misc Feature(4)1024..1287(+)
Misc Feature(5)1024..1161(+)
Misc Feature(6)1183..1275(+)
Translation
Position Chain Variation Link
4 4 g, t dbSNP:11839265
34 34 g, t dbSNP:544131704
37 37 a, c dbSNP:562532073
44 44 g, t dbSNP:529946723
66 66 c, t dbSNP:547930716
120 120 c, g dbSNP:141476503
129 129 a, g dbSNP:755391943
138 138 a, g dbSNP:779524233
144 144 c, t dbSNP:147007878
147 147 -, cagcaa dbSNP:763106197
150 150 c, g, t dbSNP:377589059
155 155 c, t dbSNP:142133640
156 156 c, t dbSNP:151081377
159 159 a, g dbSNP:746609003
161 161 a, g dbSNP:145220476
167 167 c, t dbSNP:560118670
178 178 a, g dbSNP:370964964
180 180 a, g dbSNP:759393578
184 184 a, g dbSNP:769594081
195 195 c, t dbSNP:149125997
200 200 c, t dbSNP:761793251
204 204 c, t dbSNP:767691805
208 208 a, t dbSNP:368007173
217 217 a, g dbSNP:143296005
223 223 c, g dbSNP:370590641
224 224 c, g dbSNP:760912284
232 232 c, t dbSNP:766731424
233 233 a, g dbSNP:754232617
234 234 c, g dbSNP:540233147
238 238 c, g, t dbSNP:552343736
241 241 c, t dbSNP:753307734
242 242 a, c dbSNP:746200537
243 243 a, g dbSNP:758844418
249 249 a, g dbSNP:201226091
255 255 a, g dbSNP:148316727
277 277 a, g dbSNP:746557549
314 314 a, g dbSNP:751042420
316 316 a, g dbSNP:756797263
318 318 c, g dbSNP:780816141
319 319 a, t dbSNP:575517029
321 321 a, g dbSNP:772777206
324 324 c, t dbSNP:779831451
327 327 c, t dbSNP:61729896
352 352 c, t dbSNP:768692826
353 353 c, t dbSNP:774471192
356 356 c, g, t dbSNP:747082248
369 369 a, g dbSNP:145829125
384 384 a, g dbSNP:759740467
385 385 g, t dbSNP:765412925
387 387 a, c dbSNP:775879131
388 388 c, g dbSNP:763352839
393 393 -, c dbSNP:777748261
393 393 a, g dbSNP:764550152
394 394 c, g, t dbSNP:574280988
395 395 c, g dbSNP:367588569
396 396 a, c dbSNP:749904346
398 398 c, g dbSNP:755751093
408 408 a, g, t dbSNP:779594513
421 421 a, g dbSNP:754888442
431 431 a, t dbSNP:61733784
439 439 a, g dbSNP:371431411
442 442 g, t dbSNP:748042719
450 450 c, t dbSNP:772143355
458 458 c, t dbSNP:143100244
459 459 a, g, t dbSNP:368505689
461 461 c, t dbSNP:765937307
463 463 -, ag dbSNP:753784627
464 464 a, g dbSNP:540179877
469 469 a, g dbSNP:763296052
470 470 g, t dbSNP:769065045
473 473 c, t dbSNP:113260257
481 481 a, g dbSNP:199835821
488 488 a, t dbSNP:374907767
489 489 a, g dbSNP:767940034
495 495 a, g dbSNP:753412232
498 498 a, g dbSNP:760144028
504 504 c, t dbSNP:766051820
505 505 a, g dbSNP:753604464
511 511 c, t dbSNP:754694176
514 514 a, g dbSNP:368185225
522 522 c, t dbSNP:201364984
525 525 a, g dbSNP:758365529
527 527 a, g dbSNP:777624140
545 545 a, g dbSNP:200724447
546 546 c, t dbSNP:769827681
547 547 a, g dbSNP:780306675
549 549 a, g dbSNP:749452494
554 554 c, t dbSNP:778026294
559 559 a, g dbSNP:757229441
563 563 c, t dbSNP:780039232
564 564 a, g dbSNP:749399552
567 567 a, g dbSNP:755143850
568 568 g, t dbSNP:373472360
578 578 a, t dbSNP:779154163
579 579 c, t dbSNP:748507767
582 582 c, t dbSNP:373454867
584 584 c, g dbSNP:747163107
585 585 c, g dbSNP:773640359
610 610 g, t dbSNP:111296887
614 614 c, t dbSNP:139038414
615 615 a, g dbSNP:35404413
620 620 g, t dbSNP:776235924
621 621 c, g dbSNP:759169379
630 630 a, g dbSNP:764957102
643 643 a, g dbSNP:775344684
648 648 a, g dbSNP:762791797
656 656 a, g dbSNP:763735177
657 657 c, g dbSNP:751371810
664 664 a, t dbSNP:757101069
680 680 a, g dbSNP:143960265
698 698 a, g dbSNP:762449343
702 702 c, t dbSNP:763840829
703 703 a, c dbSNP:773970722
715 715 c, t dbSNP:376677628
723 723 c, t dbSNP:767412507
725 725 c, t dbSNP:750419153
726 726 a, g dbSNP:61755283
735 735 a, g dbSNP:769253231
737 737 a, g dbSNP:765233671
740 740 c, t dbSNP:752851752
741 741 a, g dbSNP:758497518
749 749 c, t dbSNP:778102032
751 751 a, g dbSNP:751836659
758 758 -, g dbSNP:140782401
758 758 a, t dbSNP:757758557
761 761 g, t dbSNP:78810484
764 764 -, aggtt dbSNP:758038956
764 764 a, g dbSNP:200577481
767 767 -, tt dbSNP:780538544
767 767 g, t dbSNP:770432581
768 768 g, t dbSNP:779393715
770 770 a, g dbSNP:748854682
773 773 a, g dbSNP:202149829
778 778 c, t dbSNP:774093184
783 783 a, c dbSNP:369651921
784 784 c, g dbSNP:761509086
787 787 c, t dbSNP:267603811
788 788 a, g, t dbSNP:772994512
795 795 a, g dbSNP:766132764
810 810 c, t dbSNP:144283302
813 813 c, g dbSNP:183736861
815 815 a, g dbSNP:763130840
819 819 a, c dbSNP:764214378
831 831 c, t dbSNP:751861130
843 843 a, g dbSNP:757570478
854 854 c, g dbSNP:550633524
870 870 c, t dbSNP:147834946
882 882 a, g dbSNP:750852987
886 886 a, g dbSNP:756642822
893 893 c, t dbSNP:780662270
897 897 a, t dbSNP:150705387
899 899 c, t dbSNP:145298804
913 913 a, t dbSNP:370143844
920 920 c, t dbSNP:755444964
924 924 c, t dbSNP:778445360
927 927 a, g dbSNP:747678084
930 930 a, c dbSNP:758021748
933 933 c, t dbSNP:777439738
934 934 a, g dbSNP:746799158
942 942 c, g, t dbSNP:770814251
951 951 c, t dbSNP:150999500
954 954 c, t dbSNP:769653656
966 966 a, c dbSNP:372575050
970 970 c, t dbSNP:373856311
971 971 a, g dbSNP:140946240
975 975 a, g dbSNP:767819747
1005 1005 a, g dbSNP:773637248
1016 1016 a, t dbSNP:761107193
1028 1028 -, ttc dbSNP:747447718
1029 1029 a, c, t dbSNP:566648386
1034 1034 c, g dbSNP:755462450
1039 1039 a, g dbSNP:61755282
1041 1041 a, c dbSNP:199981149
1067 1067 a, g, t dbSNP:267603812
1068 1068 a, t dbSNP:746602662
1071 1071 a, c, g dbSNP:756868331
1073 1073 a, g dbSNP:745675697
1077 1077 a, g dbSNP:769751473
1080 1080 c, t dbSNP:780183027
1081 1081 a, g dbSNP:748235047
1091 1091 a, g dbSNP:772337527
1100 1100 a, c dbSNP:35918374
1108 1108 a, g dbSNP:749179710
1121 1121 a, g dbSNP:767692772
1141 1141 -, ttc dbSNP:769275091
1150 1150 c, t dbSNP:145699331
1161 1161 a, g dbSNP:180874885
1163 1163 g, t dbSNP:369777099
1164 1164 a, g dbSNP:146743791
1240 1240 a, g dbSNP:770030222
1254 1254 a, c dbSNP:775786587
1256 1256 a, g dbSNP:768461226
1277 1277 c, g dbSNP:140628294
1286 1286 a, g dbSNP:774789693
1292 1292 c, t dbSNP:145685321
1293 1293 a, g dbSNP:565998602
1301 1301 a, t dbSNP:772784183
1304 1304 a, t dbSNP:760364496
1308 1308 c, t dbSNP:138448439
1311 1311 c, t dbSNP:753652601
1312 1312 c, g dbSNP:754886422
1313 1313 a, g dbSNP:765204259
1342 1342 a, g dbSNP:752516162
1345 1345 g, t dbSNP:758356325
1357 1357 c, t dbSNP:759272566
1359 1359 a, g dbSNP:767384520
1365 1365 g, t dbSNP:764871951
1366 1366 a, t dbSNP:374549136
1368 1368 c, t dbSNP:758216737
1369 1369 c, t dbSNP:572634475
1388 1388 -, ttc dbSNP:773213910
1388 1388 c, t dbSNP:750475986
1391 1391 c, t dbSNP:199986257
1398 1398 a, g dbSNP:780245698
1401 1401 a, g dbSNP:375639121
1409 1409 c, t dbSNP:755235455
1414 1414 -, g dbSNP:35916714
1414 1414 c, t dbSNP:750978297
1419 1419 a, g dbSNP:779107107
1426 1426 c, t dbSNP:370199906
1445 1445 c, t dbSNP:772426240
1453 1453 c, t dbSNP:183429673
1462 1462 a, g dbSNP:551830455
1478 1478 c, g dbSNP:576581168
1519 1519 g, t dbSNP:568563514
1595 1595 c, g dbSNP:753848729

Target ORF information:

RefSeq Version XM_011535297
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens cyclin A1 (CCNA1), transcript variant X4, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011535297

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
ATGCACTGCA GCAACCCCAA GAGTGGAGTT GTGCTGGCTA CAGTGGCCCG AGGTCCCGAT 
GCTTGTCAGA TACTCACCAG AGCCCCGCTG GGCCAGGATC CCCCGCAGAG GACAGTGCTA
GGGCTGCTAA CTGCAAATGG GCAGTACAGG AGGACCTGTG GCCAGGGGAT CACAAGAATC
AGGTGTTATT CTGGATCAGA AAATGCCTTC CCTCCAGCTG GAAAGAAAGC ACTCCCTGAC
TGTGGGGTCC AAGAGCCCCC CAAGCAAGGG TTTGACATCT ACATGGATGA ACTAGAGCAG
GGGGACAGAG ACAGCTGCTC GGTCAGAGAG GGGATGGCAT TTGAGGATGT GTATGAAGTA
GACACCGGCA CACTCAAGTC AGACCTGCAC TTCCTGCTGG ATTTCAACAC AGTTTCCCCT
ATGCTGGTAG ATTCATCTCT CCTCTCCCAG TCTGAAGATA TATCCAGTCT TGGCACAGAT
GTGATAAATG TGACTGAATA TGCTGAAGAA ATTTATCAGT ACCTTAGGGA AGCTGAAATA
AGGCACAGAC CCAAAGCACA CTACATGAAG AAGCAGCCAG ACATCACGGA AGGCATGCGC
ACGATTCTGG TGGACTGGCT GGTGGAGGTT GGGGAAGAAT ATAAACTTCG AGCAGAGACC
CTGTATCTGG CTGTCAACTT CCTGGACAGG TTCCTTTCAT GTATGTCTGT TCTGAGAGGG
AAACTGCAGC TCGTAGGAAC AGCAGCTATG CTTTTGGCTT CGAAATATGA AGAGATATAT
CCTCCTGAAG TAGACGAGTT TGTCTATATC ACCGATGATA CATACACAAA ACGACAACTG
TTAAAAATGG AACACTTGCT TCTGAAAGTT CTAGCTTTTG ATCTGACAGT ACCAACCACC
AACCAGTTTC TCCTTCAGTA CTTGAGGCGA CAAGGAGTGT GCGTCAGGAC TGAGAACCTG
GCTAAGTACG TAGCAGAGCT GAGTCTACTT GAAGCAGATC CATTCTTGAA ATATCTTCCT
TCACTGATAG CTGCAGCAGC TTTTTGCCTG GCAAACTATA CTGTGAACAA GCACTTTTGG
CCAGAAACCC TTGCTGCATT TACAGGGTAT TCATTAAGTG AAATTGTGCC TTGCCTGAGT
GAGCTTCATA AAGCGTACCT TGATATACCC CATCGACCTC AGCAAGCAAT TAGGGAGAAG
TACAAGGCTT CAAAGTACCT GTGTGTGTCC CTCATGGAGC CACCTGCAGT TCTTCTTCTA
CAATAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu25389
Accession Version NM_003914.3 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1398bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product cyclin-A1 isoform a
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC396283.1, DC411883.1, U66838.1 and AA553454.1. On Nov 30, 2007 this sequence version replaced gi:16306528. Summary: The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. The cyclin encoded by this gene was shown to be expressed in testis and brain, as well as in several leukemic cell lines, and is thought to primarily function in the control of the germline meiotic cell cycle. This cyclin binds both CDK2 and CDC2 kinases, which give two distinct kinase activities, one appearing in S phase, the other in G2, and thus regulate separate functions in cell cycle. This cyclin was found to bind to important cell cycle regulators, such as Rb family proteins, transcription factor E2F-1, and the p21 family proteins. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK314261.1, U66838.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2144333 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
ATGGAGACCG GCTTTCCCGC AATCATGTAC CCTGGATCTT TTATTGGGGG CTGGGGAGAA 
GAGTATCTCA GCTGGGAAGG ACCGGGGCTC CCAGATTTCG TCTTCCAGCA GCAGCCCGTG
GAGTCTGAAG CAATGCACTG CAGCAACCCC AAGAGTGGAG TTGTGCTGGC TACAGTGGCC
CGAGGTCCCG ATGCTTGTCA GATACTCACC AGAGCCCCGC TGGGCCAGGA TCCCCCGCAG
AGGACAGTGC TAGGGCTGCT AACTGCAAAT GGGCAGTACA GGAGGACCTG TGGCCAGGGG
ATCACAAGAA TCAGGTGTTA TTCTGGATCA GAAAATGCCT TCCCTCCAGC TGGAAAGAAA
GCACTCCCTG ACTGTGGGGT CCAAGAGCCC CCCAAGCAAG GGTTTGACAT CTACATGGAT
GAACTAGAGC AGGGGGACAG AGACAGCTGC TCGGTCAGAG AGGGGATGGC ATTTGAGGAT
GTGTATGAAG TAGACACCGG CACACTCAAG TCAGACCTGC ACTTCCTGCT GGATTTCAAC
ACAGTTTCCC CTATGCTGGT AGATTCATCT CTCCTCTCCC AGTCTGAAGA TATATCCAGT
CTTGGCACAG ATGTGATAAA TGTGACTGAA TATGCTGAAG AAATTTATCA GTACCTTAGG
GAAGCTGAAA TAAGGCACAG ACCCAAAGCA CACTACATGA AGAAGCAGCC AGACATCACG
GAAGGCATGC GCACGATTCT GGTGGACTGG CTGGTGGAGG TTGGGGAAGA ATATAAACTT
CGAGCAGAGA CCCTGTATCT GGCTGTCAAC TTCCTGGACA GGTTCCTTTC ATGTATGTCT
GTTCTGAGAG GGAAACTGCA GCTCGTAGGA ACAGCAGCTA TGCTTTTGGC TTCGAAATAT
GAAGAGATAT ATCCTCCTGA AGTAGACGAG TTTGTCTATA TCACCGATGA TACATACACA
AAACGACAAC TGTTAAAAAT GGAACACTTG CTTCTGAAAG TTCTAGCTTT TGATCTGACA
GTACCAACCA CCAACCAGTT TCTCCTTCAG TACTTGAGGC GACAAGGAGT GTGCGTCAGG
ACTGAGAACC TGGCTAAGTA CGTAGCAGAG CTGAGTCTAC TTGAAGCAGA TCCATTCTTG
AAATATCTTC CTTCACTGAT AGCTGCAGCA GCTTTTTGCC TGGCAAACTA TACTGTGAAC
AAGCACTTTT GGCCAGAAAC CCTTGCTGCA TTTACAGGGT ATTCATTAAG TGAAATTGTG
CCTTGCCTGA GTGAGCTTCA TAAAGCGTAC CTTGATATAC CCCATCGACC TCAGCAAGCA
ATTAGGGAGA AGTACAAGGC TTCAAAGTAC CTGTGTGTGT CCCTCATGGA GCCACCTGCA
GTTCTTCTTC TACAATAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeqNP_003905.1
CDS351..1748
Misc Feature(1)240..242(+)
Misc Feature(2)1077..1346(+)
Misc Feature(3)1077..1211(+)
Misc Feature(4)1233..1334(+)
Misc Feature(5)1368..1631(+)
Misc Feature(6)1368..1505(+)
Misc Feature(7)1527..1619(+)
Exon (1)1..458
Gene:CCNA1
Gene Synonym:
Exon (2)459..647
Gene:CCNA1
Gene Synonym:
Exon (3)648..894
Gene:CCNA1
Gene Synonym:
Exon (4)895..1019
Gene:CCNA1
Gene Synonym:
Exon (5)1020..1243
Gene:CCNA1
Gene Synonym:
Exon (6)1244..1448
Gene:CCNA1
Gene Synonym:
Exon (7)1449..1562
Gene:CCNA1
Gene Synonym:
Exon (8)1563..1696
Gene:CCNA1
Gene Synonym:
Exon (9)1697..1965
Gene:CCNA1
Gene Synonym:
Translation
Position Chain Variation Link
5 5 a, g dbSNP:764993851
38 38 c, t dbSNP:577770881
51 51 c, g dbSNP:765164080
55 55 c, g dbSNP:7985423
64 64 c, t dbSNP:551274389
66 66 c, t dbSNP:375639175
67 67 g, t dbSNP:573116595
129 129 g, t dbSNP:540249310
133 133 c, t dbSNP:564806927
174 174 g, t dbSNP:11839265
204 204 g, t dbSNP:544131704
207 207 a, c dbSNP:562532073
214 214 g, t dbSNP:529946723
236 236 c, t dbSNP:547930716
299 299 c, t dbSNP:566570190
308 308 a, g, t dbSNP:370767056
311 311 a, g dbSNP:761663997
313 313 g, t dbSNP:767273156
322 322 c, g dbSNP:750238392
327 327 a, c, g dbSNP:75259848
340 340 c, g dbSNP:373951116
341 341 g, t dbSNP:758177732
344 344 a, g dbSNP:778054783
359 359 a, c dbSNP:747257303
361 361 g, t dbSNP:757517822
373 373 a, t dbSNP:201966146
375 375 a, g dbSNP:746262330
380 380 a, c, t dbSNP:770373399
382 382 c, g dbSNP:748774557
392 392 c, t dbSNP:768345943
396 396 -, g dbSNP:776844268
398 398 a, g dbSNP:774039740
400 400 g, t dbSNP:761313033
408 408 a, g dbSNP:139574122
409 409 -, a dbSNP:762041001
413 413 -, gtatc dbSNP:765244642
419 419 c, t dbSNP:767231656
424 424 a, g dbSNP:772834378
425 425 a, g dbSNP:760514627
429 429 a, g dbSNP:113565588
430 430 a, g dbSNP:376028215
433 433 a, c, t dbSNP:758461650
435 435 a, g dbSNP:541845241
437 437 a, c, g dbSNP:140980274
440 440 c, t dbSNP:746209396
451 451 c, t dbSNP:778026191
458 458 -, g dbSNP:575052246
464 464 c, g dbSNP:141476503
473 473 a, g dbSNP:755391943
482 482 a, g dbSNP:779524233
488 488 c, t dbSNP:147007878
491 491 -, cagcaa dbSNP:763106197
494 494 c, g, t dbSNP:377589059
499 499 c, t dbSNP:142133640
500 500 c, t dbSNP:151081377
503 503 a, g dbSNP:746609003
505 505 a, g dbSNP:145220476
511 511 c, t dbSNP:560118670
522 522 a, g dbSNP:370964964
524 524 a, g dbSNP:759393578
528 528 a, g dbSNP:769594081
539 539 c, t dbSNP:149125997
544 544 c, t dbSNP:761793251
548 548 c, t dbSNP:767691805
552 552 a, t dbSNP:368007173
561 561 a, g dbSNP:143296005
567 567 c, g dbSNP:370590641
568 568 c, g dbSNP:760912284
576 576 c, t dbSNP:766731424
577 577 a, g dbSNP:754232617
578 578 c, g dbSNP:540233147
582 582 c, g, t dbSNP:552343736
585 585 c, t dbSNP:753307734
586 586 a, c dbSNP:746200537
587 587 a, g dbSNP:758844418
593 593 a, g dbSNP:201226091
599 599 a, g dbSNP:148316727
621 621 a, g dbSNP:746557549
658 658 a, g dbSNP:751042420
660 660 a, g dbSNP:756797263
662 662 c, g dbSNP:780816141
663 663 a, t dbSNP:575517029
665 665 a, g dbSNP:772777206
668 668 c, t dbSNP:779831451
671 671 c, t dbSNP:61729896
696 696 c, t dbSNP:768692826
697 697 c, t dbSNP:774471192
700 700 c, g, t dbSNP:747082248
713 713 a, g dbSNP:145829125
728 728 a, g dbSNP:759740467
729 729 g, t dbSNP:765412925
731 731 a, c dbSNP:775879131
732 732 c, g dbSNP:763352839
737 737 -, c dbSNP:777748261
737 737 a, g dbSNP:764550152
738 738 c, g, t dbSNP:574280988
739 739 c, g dbSNP:367588569
740 740 a, c dbSNP:749904346
742 742 c, g dbSNP:755751093
752 752 a, g, t dbSNP:779594513
765 765 a, g dbSNP:754888442
775 775 a, t dbSNP:61733784
783 783 a, g dbSNP:371431411
786 786 g, t dbSNP:748042719
794 794 c, t dbSNP:772143355
802 802 c, t dbSNP:143100244
803 803 a, g, t dbSNP:368505689
805 805 c, t dbSNP:765937307
807 807 -, ag dbSNP:753784627
808 808 a, g dbSNP:540179877
813 813 a, g dbSNP:763296052
814 814 g, t dbSNP:769065045
817 817 c, t dbSNP:113260257
825 825 a, g dbSNP:199835821
832 832 a, t dbSNP:374907767
833 833 a, g dbSNP:767940034
839 839 a, g dbSNP:753412232
842 842 a, g dbSNP:760144028
848 848 c, t dbSNP:766051820
849 849 a, g dbSNP:753604464
855 855 c, t dbSNP:754694176
858 858 a, g dbSNP:368185225
866 866 c, t dbSNP:201364984
869 869 a, g dbSNP:758365529
871 871 a, g dbSNP:777624140
889 889 a, g dbSNP:200724447
890 890 c, t dbSNP:769827681
891 891 a, g dbSNP:780306675
893 893 a, g dbSNP:749452494
898 898 c, t dbSNP:778026294
903 903 a, g dbSNP:757229441
907 907 c, t dbSNP:780039232
908 908 a, g dbSNP:749399552
911 911 a, g dbSNP:755143850
912 912 g, t dbSNP:373472360
922 922 a, t dbSNP:779154163
923 923 c, t dbSNP:748507767
926 926 c, t dbSNP:373454867
928 928 c, g dbSNP:747163107
929 929 c, g dbSNP:773640359
954 954 g, t dbSNP:111296887
958 958 c, t dbSNP:139038414
959 959 a, g dbSNP:35404413
964 964 g, t dbSNP:776235924
965 965 c, g dbSNP:759169379
974 974 a, g dbSNP:764957102
987 987 a, g dbSNP:775344684
992 992 a, g dbSNP:762791797
1000 1000 a, g dbSNP:763735177
1001 1001 c, g dbSNP:751371810
1008 1008 a, t dbSNP:757101069
1024 1024 a, g dbSNP:143960265
1042 1042 a, g dbSNP:762449343
1046 1046 c, t dbSNP:763840829
1047 1047 a, c dbSNP:773970722
1059 1059 c, t dbSNP:376677628
1067 1067 c, t dbSNP:767412507
1069 1069 c, t dbSNP:750419153
1070 1070 a, g dbSNP:61755283
1079 1079 a, g dbSNP:769253231
1081 1081 a, g dbSNP:765233671
1084 1084 c, t dbSNP:752851752
1085 1085 a, g dbSNP:758497518
1093 1093 c, t dbSNP:778102032
1095 1095 a, g dbSNP:751836659
1102 1102 -, g dbSNP:140782401
1102 1102 a, t dbSNP:757758557
1105 1105 g, t dbSNP:78810484
1108 1108 -, aggtt dbSNP:758038956
1108 1108 a, g dbSNP:200577481
1111 1111 -, tt dbSNP:780538544
1111 1111 g, t dbSNP:770432581
1112 1112 g, t dbSNP:779393715
1114 1114 a, g dbSNP:748854682
1117 1117 a, g dbSNP:202149829
1122 1122 c, t dbSNP:774093184
1127 1127 a, c dbSNP:369651921
1128 1128 c, g dbSNP:761509086
1131 1131 c, t dbSNP:267603811
1132 1132 a, g, t dbSNP:772994512
1139 1139 a, g dbSNP:766132764
1154 1154 c, t dbSNP:144283302
1157 1157 c, g dbSNP:183736861
1159 1159 a, g dbSNP:763130840
1163 1163 a, c dbSNP:764214378
1175 1175 c, t dbSNP:751861130
1187 1187 a, g dbSNP:757570478
1198 1198 c, g dbSNP:550633524
1214 1214 c, t dbSNP:147834946
1226 1226 a, g dbSNP:750852987
1230 1230 a, g dbSNP:756642822
1237 1237 c, t dbSNP:780662270
1241 1241 a, t dbSNP:150705387
1243 1243 c, t dbSNP:145298804
1257 1257 a, t dbSNP:370143844
1264 1264 c, t dbSNP:755444964
1268 1268 c, t dbSNP:778445360
1271 1271 a, g dbSNP:747678084
1274 1274 a, c dbSNP:758021748
1277 1277 c, t dbSNP:777439738
1278 1278 a, g dbSNP:746799158
1286 1286 c, g, t dbSNP:770814251
1295 1295 c, t dbSNP:150999500
1298 1298 c, t dbSNP:769653656
1310 1310 a, c dbSNP:372575050
1314 1314 c, t dbSNP:373856311
1315 1315 a, g dbSNP:140946240
1319 1319 a, g dbSNP:767819747
1349 1349 a, g dbSNP:773637248
1360 1360 a, t dbSNP:761107193
1372 1372 -, ttc dbSNP:747447718
1373 1373 a, c, t dbSNP:566648386
1378 1378 c, g dbSNP:755462450
1383 1383 a, g dbSNP:61755282
1385 1385 a, c dbSNP:199981149
1411 1411 a, g, t dbSNP:267603812
1412 1412 a, t dbSNP:746602662
1415 1415 a, c, g dbSNP:756868331
1417 1417 a, g dbSNP:745675697
1421 1421 a, g dbSNP:769751473
1424 1424 c, t dbSNP:780183027
1425 1425 a, g dbSNP:748235047
1435 1435 a, g dbSNP:772337527
1444 1444 a, c dbSNP:35918374
1452 1452 a, g dbSNP:749179710
1465 1465 a, g dbSNP:767692772
1485 1485 -, ttc dbSNP:769275091
1494 1494 c, t dbSNP:145699331
1505 1505 a, g dbSNP:180874885
1507 1507 g, t dbSNP:369777099
1508 1508 a, g dbSNP:146743791
1584 1584 a, g dbSNP:770030222
1598 1598 a, c dbSNP:775786587
1600 1600 a, g dbSNP:768461226
1621 1621 c, g dbSNP:140628294
1630 1630 a, g dbSNP:774789693
1636 1636 c, t dbSNP:145685321
1637 1637 a, g dbSNP:565998602
1645 1645 a, t dbSNP:772784183
1648 1648 a, t dbSNP:760364496
1652 1652 c, t dbSNP:138448439
1655 1655 c, t dbSNP:753652601
1656 1656 c, g dbSNP:754886422
1657 1657 a, g dbSNP:765204259
1686 1686 a, g dbSNP:752516162
1689 1689 g, t dbSNP:758356325
1701 1701 c, t dbSNP:759272566
1703 1703 a, g dbSNP:767384520
1709 1709 g, t dbSNP:764871951
1710 1710 a, t dbSNP:374549136
1712 1712 c, t dbSNP:758216737
1713 1713 c, t dbSNP:572634475
1732 1732 -, ttc dbSNP:773213910
1732 1732 c, t dbSNP:750475986
1735 1735 c, t dbSNP:199986257
1742 1742 a, g dbSNP:780245698
1745 1745 a, g dbSNP:375639121
1753 1753 c, t dbSNP:755235455
1758 1758 -, g dbSNP:35916714
1758 1758 c, t dbSNP:750978297
1763 1763 a, g dbSNP:779107107
1770 1770 c, t dbSNP:370199906
1789 1789 c, t dbSNP:772426240
1797 1797 c, t dbSNP:183429673
1806 1806 a, g dbSNP:551830455
1822 1822 c, g dbSNP:576581168
1863 1863 g, t dbSNP:568563514
1939 1939 c, g dbSNP:753848729

Target ORF information:

RefSeq Version NM_003914
Organism Homo sapiens (human)
Definition Homo sapiens cyclin A1 (CCNA1), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_003914

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
ATGGAGACCG GCTTTCCCGC AATCATGTAC CCTGGATCTT TTATTGGGGG CTGGGGAGAA 
GAGTATCTCA GCTGGGAAGG ACCGGGGCTC CCAGATTTCG TCTTCCAGCA GCAGCCCGTG
GAGTCTGAAG CAATGCACTG CAGCAACCCC AAGAGTGGAG TTGTGCTGGC TACAGTGGCC
CGAGGTCCCG ATGCTTGTCA GATACTCACC AGAGCCCCGC TGGGCCAGGA TCCCCCGCAG
AGGACAGTGC TAGGGCTGCT AACTGCAAAT GGGCAGTACA GGAGGACCTG TGGCCAGGGG
ATCACAAGAA TCAGGTGTTA TTCTGGATCA GAAAATGCCT TCCCTCCAGC TGGAAAGAAA
GCACTCCCTG ACTGTGGGGT CCAAGAGCCC CCCAAGCAAG GGTTTGACAT CTACATGGAT
GAACTAGAGC AGGGGGACAG AGACAGCTGC TCGGTCAGAG AGGGGATGGC ATTTGAGGAT
GTGTATGAAG TAGACACCGG CACACTCAAG TCAGACCTGC ACTTCCTGCT GGATTTCAAC
ACAGTTTCCC CTATGCTGGT AGATTCATCT CTCCTCTCCC AGTCTGAAGA TATATCCAGT
CTTGGCACAG ATGTGATAAA TGTGACTGAA TATGCTGAAG AAATTTATCA GTACCTTAGG
GAAGCTGAAA TAAGGCACAG ACCCAAAGCA CACTACATGA AGAAGCAGCC AGACATCACG
GAAGGCATGC GCACGATTCT GGTGGACTGG CTGGTGGAGG TTGGGGAAGA ATATAAACTT
CGAGCAGAGA CCCTGTATCT GGCTGTCAAC TTCCTGGACA GGTTCCTTTC ATGTATGTCT
GTTCTGAGAG GGAAACTGCA GCTCGTAGGA ACAGCAGCTA TGCTTTTGGC TTCGAAATAT
GAAGAGATAT ATCCTCCTGA AGTAGACGAG TTTGTCTATA TCACCGATGA TACATACACA
AAACGACAAC TGTTAAAAAT GGAACACTTG CTTCTGAAAG TTCTAGCTTT TGATCTGACA
GTACCAACCA CCAACCAGTT TCTCCTTCAG TACTTGAGGC GACAAGGAGT GTGCGTCAGG
ACTGAGAACC TGGCTAAGTA CGTAGCAGAG CTGAGTCTAC TTGAAGCAGA TCCATTCTTG
AAATATCTTC CTTCACTGAT AGCTGCAGCA GCTTTTTGCC TGGCAAACTA TACTGTGAAC
AAGCACTTTT GGCCAGAAAC CCTTGCTGCA TTTACAGGGT ATTCATTAAG TGAAATTGTG
CCTTGCCTGA GTGAGCTTCA TAAAGCGTAC CTTGATATAC CCCATCGACC TCAGCAAGCA
ATTAGGGAGA AGTACAAGGC TTCAAAGTAC CTGTGTGTGT CCCTCATGGA GCCACCTGCA
GTTCTTCTTC TACAATAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu25558
Accession Version NM_001111045.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1395bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product cyclin-A1 isoform b
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC396283.1, DC411883.1, BC036346.1 and AA553454.1. Summary: The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. The cyclin encoded by this gene was shown to be expressed in testis and brain, as well as in several leukemic cell lines, and is thought to primarily function in the control of the germline meiotic cell cycle. This cyclin binds both CDK2 and CDC2 kinases, which give two distinct kinase activities, one appearing in S phase, the other in G2, and thus regulate separate functions in cell cycle. This cyclin was found to bind to important cell cycle regulators, such as Rb family proteins, transcription factor E2F-1, and the p21 family proteins. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]. Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 5' coding region, compared to variant 1, resulting in a protein (isoform b) that is 1 amino acid shorter than isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC035479.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2144333 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
ATGGAGACCG GCTTTCCCGC AATCATGTAC CCTGGATCTT TTATTGGGGG CTGGGGAGAA 
GAGTATCTCA GCTGGGAAGG ACCGGGGCTC CCAGATTTCG TCTTCCAGCA GCCCGTGGAG
TCTGAAGCAA TGCACTGCAG CAACCCCAAG AGTGGAGTTG TGCTGGCTAC AGTGGCCCGA
GGTCCCGATG CTTGTCAGAT ACTCACCAGA GCCCCGCTGG GCCAGGATCC CCCGCAGAGG
ACAGTGCTAG GGCTGCTAAC TGCAAATGGG CAGTACAGGA GGACCTGTGG CCAGGGGATC
ACAAGAATCA GGTGTTATTC TGGATCAGAA AATGCCTTCC CTCCAGCTGG AAAGAAAGCA
CTCCCTGACT GTGGGGTCCA AGAGCCCCCC AAGCAAGGGT TTGACATCTA CATGGATGAA
CTAGAGCAGG GGGACAGAGA CAGCTGCTCG GTCAGAGAGG GGATGGCATT TGAGGATGTG
TATGAAGTAG ACACCGGCAC ACTCAAGTCA GACCTGCACT TCCTGCTGGA TTTCAACACA
GTTTCCCCTA TGCTGGTAGA TTCATCTCTC CTCTCCCAGT CTGAAGATAT ATCCAGTCTT
GGCACAGATG TGATAAATGT GACTGAATAT GCTGAAGAAA TTTATCAGTA CCTTAGGGAA
GCTGAAATAA GGCACAGACC CAAAGCACAC TACATGAAGA AGCAGCCAGA CATCACGGAA
GGCATGCGCA CGATTCTGGT GGACTGGCTG GTGGAGGTTG GGGAAGAATA TAAACTTCGA
GCAGAGACCC TGTATCTGGC TGTCAACTTC CTGGACAGGT TCCTTTCATG TATGTCTGTT
CTGAGAGGGA AACTGCAGCT CGTAGGAACA GCAGCTATGC TTTTGGCTTC GAAATATGAA
GAGATATATC CTCCTGAAGT AGACGAGTTT GTCTATATCA CCGATGATAC ATACACAAAA
CGACAACTGT TAAAAATGGA ACACTTGCTT CTGAAAGTTC TAGCTTTTGA TCTGACAGTA
CCAACCACCA ACCAGTTTCT CCTTCAGTAC TTGAGGCGAC AAGGAGTGTG CGTCAGGACT
GAGAACCTGG CTAAGTACGT AGCAGAGCTG AGTCTACTTG AAGCAGATCC ATTCTTGAAA
TATCTTCCTT CACTGATAGC TGCAGCAGCT TTTTGCCTGG CAAACTATAC TGTGAACAAG
CACTTTTGGC CAGAAACCCT TGCTGCATTT ACAGGGTATT CATTAAGTGA AATTGTGCCT
TGCCTGAGTG AGCTTCATAA AGCGTACCTT GATATACCCC ATCGACCTCA GCAAGCAATT
AGGGAGAAGT ACAAGGCTTC AAAGTACCTG TGTGTGTCCC TCATGGAGCC ACCTGCAGTT
CTTCTTCTAC AATAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeqNP_001104515.1
CDS351..1745
Misc Feature(1)240..242(+)
Misc Feature(2)1074..1343(+)
Misc Feature(3)1074..1208(+)
Misc Feature(4)1230..1331(+)
Misc Feature(5)1365..1628(+)
Misc Feature(6)1365..1502(+)
Misc Feature(7)1524..1616(+)
Exon (1)1..458
Gene:CCNA1
Gene Synonym:
Exon (2)459..644
Gene:CCNA1
Gene Synonym:
Exon (3)645..891
Gene:CCNA1
Gene Synonym:
Exon (4)892..1016
Gene:CCNA1
Gene Synonym:
Exon (5)1017..1240
Gene:CCNA1
Gene Synonym:
Exon (6)1241..1445
Gene:CCNA1
Gene Synonym:
Exon (7)1446..1559
Gene:CCNA1
Gene Synonym:
Exon (8)1560..1693
Gene:CCNA1
Gene Synonym:
Exon (9)1694..1962
Gene:CCNA1
Gene Synonym:
Translation
Position Chain Variation Link
5 5 a, g dbSNP:764993851
38 38 c, t dbSNP:577770881
51 51 c, g dbSNP:765164080
55 55 c, g dbSNP:7985423
64 64 c, t dbSNP:551274389
66 66 c, t dbSNP:375639175
67 67 g, t dbSNP:573116595
129 129 g, t dbSNP:540249310
133 133 c, t dbSNP:564806927
174 174 g, t dbSNP:11839265
204 204 g, t dbSNP:544131704
207 207 a, c dbSNP:562532073
214 214 g, t dbSNP:529946723
236 236 c, t dbSNP:547930716
299 299 c, t dbSNP:566570190
308 308 a, g, t dbSNP:370767056
311 311 a, g dbSNP:761663997
313 313 g, t dbSNP:767273156
322 322 c, g dbSNP:750238392
327 327 a, c, g dbSNP:75259848
340 340 c, g dbSNP:373951116
341 341 g, t dbSNP:758177732
344 344 a, g dbSNP:778054783
359 359 a, c dbSNP:747257303
361 361 g, t dbSNP:757517822
373 373 a, t dbSNP:201966146
375 375 a, g dbSNP:746262330
380 380 a, c, t dbSNP:770373399
382 382 c, g dbSNP:748774557
392 392 c, t dbSNP:768345943
396 396 -, g dbSNP:776844268
398 398 a, g dbSNP:774039740
400 400 g, t dbSNP:761313033
408 408 a, g dbSNP:139574122
409 409 -, a dbSNP:762041001
413 413 -, gtatc dbSNP:765244642
419 419 c, t dbSNP:767231656
424 424 a, g dbSNP:772834378
425 425 a, g dbSNP:760514627
429 429 a, g dbSNP:113565588
430 430 a, g dbSNP:376028215
433 433 a, c, t dbSNP:758461650
435 435 a, g dbSNP:541845241
437 437 a, c, g dbSNP:140980274
440 440 c, t dbSNP:746209396
451 451 c, t dbSNP:778026191
458 458 -, g dbSNP:575052246
461 461 c, g dbSNP:141476503
470 470 a, g dbSNP:755391943
479 479 a, g dbSNP:779524233
485 485 c, t dbSNP:147007878
488 488 -, cagcaa dbSNP:763106197
491 491 c, g, t dbSNP:377589059
496 496 c, t dbSNP:142133640
497 497 c, t dbSNP:151081377
500 500 a, g dbSNP:746609003
502 502 a, g dbSNP:145220476
508 508 c, t dbSNP:560118670
519 519 a, g dbSNP:370964964
521 521 a, g dbSNP:759393578
525 525 a, g dbSNP:769594081
536 536 c, t dbSNP:149125997
541 541 c, t dbSNP:761793251
545 545 c, t dbSNP:767691805
549 549 a, t dbSNP:368007173
558 558 a, g dbSNP:143296005
564 564 c, g dbSNP:370590641
565 565 c, g dbSNP:760912284
573 573 c, t dbSNP:766731424
574 574 a, g dbSNP:754232617
575 575 c, g dbSNP:540233147
579 579 c, g, t dbSNP:552343736
582 582 c, t dbSNP:753307734
583 583 a, c dbSNP:746200537
584 584 a, g dbSNP:758844418
590 590 a, g dbSNP:201226091
596 596 a, g dbSNP:148316727
618 618 a, g dbSNP:746557549
655 655 a, g dbSNP:751042420
657 657 a, g dbSNP:756797263
659 659 c, g dbSNP:780816141
660 660 a, t dbSNP:575517029
662 662 a, g dbSNP:772777206
665 665 c, t dbSNP:779831451
668 668 c, t dbSNP:61729896
693 693 c, t dbSNP:768692826
694 694 c, t dbSNP:774471192
697 697 c, g, t dbSNP:747082248
710 710 a, g dbSNP:145829125
725 725 a, g dbSNP:759740467
726 726 g, t dbSNP:765412925
728 728 a, c dbSNP:775879131
729 729 c, g dbSNP:763352839
734 734 -, c dbSNP:777748261
734 734 a, g dbSNP:764550152
735 735 c, g, t dbSNP:574280988
736 736 c, g dbSNP:367588569
737 737 a, c dbSNP:749904346
739 739 c, g dbSNP:755751093
749 749 a, g, t dbSNP:779594513
762 762 a, g dbSNP:754888442
772 772 a, t dbSNP:61733784
780 780 a, g dbSNP:371431411
783 783 g, t dbSNP:748042719
791 791 c, t dbSNP:772143355
799 799 c, t dbSNP:143100244
800 800 a, g, t dbSNP:368505689
802 802 c, t dbSNP:765937307
804 804 -, ag dbSNP:753784627
805 805 a, g dbSNP:540179877
810 810 a, g dbSNP:763296052
811 811 g, t dbSNP:769065045
814 814 c, t dbSNP:113260257
822 822 a, g dbSNP:199835821
829 829 a, t dbSNP:374907767
830 830 a, g dbSNP:767940034
836 836 a, g dbSNP:753412232
839 839 a, g dbSNP:760144028
845 845 c, t dbSNP:766051820
846 846 a, g dbSNP:753604464
852 852 c, t dbSNP:754694176
855 855 a, g dbSNP:368185225
863 863 c, t dbSNP:201364984
866 866 a, g dbSNP:758365529
868 868 a, g dbSNP:777624140
886 886 a, g dbSNP:200724447
887 887 c, t dbSNP:769827681
888 888 a, g dbSNP:780306675
890 890 a, g dbSNP:749452494
895 895 c, t dbSNP:778026294
900 900 a, g dbSNP:757229441
904 904 c, t dbSNP:780039232
905 905 a, g dbSNP:749399552
908 908 a, g dbSNP:755143850
909 909 g, t dbSNP:373472360
919 919 a, t dbSNP:779154163
920 920 c, t dbSNP:748507767
923 923 c, t dbSNP:373454867
925 925 c, g dbSNP:747163107
926 926 c, g dbSNP:773640359
951 951 g, t dbSNP:111296887
955 955 c, t dbSNP:139038414
956 956 a, g dbSNP:35404413
961 961 g, t dbSNP:776235924
962 962 c, g dbSNP:759169379
971 971 a, g dbSNP:764957102
984 984 a, g dbSNP:775344684
989 989 a, g dbSNP:762791797
997 997 a, g dbSNP:763735177
998 998 c, g dbSNP:751371810
1005 1005 a, t dbSNP:757101069
1021 1021 a, g dbSNP:143960265
1039 1039 a, g dbSNP:762449343
1043 1043 c, t dbSNP:763840829
1044 1044 a, c dbSNP:773970722
1056 1056 c, t dbSNP:376677628
1064 1064 c, t dbSNP:767412507
1066 1066 c, t dbSNP:750419153
1067 1067 a, g dbSNP:61755283
1076 1076 a, g dbSNP:769253231
1078 1078 a, g dbSNP:765233671
1081 1081 c, t dbSNP:752851752
1082 1082 a, g dbSNP:758497518
1090 1090 c, t dbSNP:778102032
1092 1092 a, g dbSNP:751836659
1099 1099 -, g dbSNP:140782401
1099 1099 a, t dbSNP:757758557
1102 1102 g, t dbSNP:78810484
1105 1105 -, aggtt dbSNP:758038956
1105 1105 a, g dbSNP:200577481
1108 1108 -, tt dbSNP:780538544
1108 1108 g, t dbSNP:770432581
1109 1109 g, t dbSNP:779393715
1111 1111 a, g dbSNP:748854682
1114 1114 a, g dbSNP:202149829
1119 1119 c, t dbSNP:774093184
1124 1124 a, c dbSNP:369651921
1125 1125 c, g dbSNP:761509086
1128 1128 c, t dbSNP:267603811
1129 1129 a, g, t dbSNP:772994512
1136 1136 a, g dbSNP:766132764
1151 1151 c, t dbSNP:144283302
1154 1154 c, g dbSNP:183736861
1156 1156 a, g dbSNP:763130840
1160 1160 a, c dbSNP:764214378
1172 1172 c, t dbSNP:751861130
1184 1184 a, g dbSNP:757570478
1195 1195 c, g dbSNP:550633524
1211 1211 c, t dbSNP:147834946
1223 1223 a, g dbSNP:750852987
1227 1227 a, g dbSNP:756642822
1234 1234 c, t dbSNP:780662270
1238 1238 a, t dbSNP:150705387
1240 1240 c, t dbSNP:145298804
1254 1254 a, t dbSNP:370143844
1261 1261 c, t dbSNP:755444964
1265 1265 c, t dbSNP:778445360
1268 1268 a, g dbSNP:747678084
1271 1271 a, c dbSNP:758021748
1274 1274 c, t dbSNP:777439738
1275 1275 a, g dbSNP:746799158
1283 1283 c, g, t dbSNP:770814251
1292 1292 c, t dbSNP:150999500
1295 1295 c, t dbSNP:769653656
1307 1307 a, c dbSNP:372575050
1311 1311 c, t dbSNP:373856311
1312 1312 a, g dbSNP:140946240
1316 1316 a, g dbSNP:767819747
1346 1346 a, g dbSNP:773637248
1357 1357 a, t dbSNP:761107193
1369 1369 -, ttc dbSNP:747447718
1370 1370 a, c, t dbSNP:566648386
1375 1375 c, g dbSNP:755462450
1380 1380 a, g dbSNP:61755282
1382 1382 a, c dbSNP:199981149
1408 1408 a, g, t dbSNP:267603812
1409 1409 a, t dbSNP:746602662
1412 1412 a, c, g dbSNP:756868331
1414 1414 a, g dbSNP:745675697
1418 1418 a, g dbSNP:769751473
1421 1421 c, t dbSNP:780183027
1422 1422 a, g dbSNP:748235047
1432 1432 a, g dbSNP:772337527
1441 1441 a, c dbSNP:35918374
1449 1449 a, g dbSNP:749179710
1462 1462 a, g dbSNP:767692772
1482 1482 -, ttc dbSNP:769275091
1491 1491 c, t dbSNP:145699331
1502 1502 a, g dbSNP:180874885
1504 1504 g, t dbSNP:369777099
1505 1505 a, g dbSNP:146743791
1581 1581 a, g dbSNP:770030222
1595 1595 a, c dbSNP:775786587
1597 1597 a, g dbSNP:768461226
1618 1618 c, g dbSNP:140628294
1627 1627 a, g dbSNP:774789693
1633 1633 c, t dbSNP:145685321
1634 1634 a, g dbSNP:565998602
1642 1642 a, t dbSNP:772784183
1645 1645 a, t dbSNP:760364496
1649 1649 c, t dbSNP:138448439
1652 1652 c, t dbSNP:753652601
1653 1653 c, g dbSNP:754886422
1654 1654 a, g dbSNP:765204259
1683 1683 a, g dbSNP:752516162
1686 1686 g, t dbSNP:758356325
1698 1698 c, t dbSNP:759272566
1700 1700 a, g dbSNP:767384520
1706 1706 g, t dbSNP:764871951
1707 1707 a, t dbSNP:374549136
1709 1709 c, t dbSNP:758216737
1710 1710 c, t dbSNP:572634475
1729 1729 -, ttc dbSNP:773213910
1729 1729 c, t dbSNP:750475986
1732 1732 c, t dbSNP:199986257
1739 1739 a, g dbSNP:780245698
1742 1742 a, g dbSNP:375639121
1750 1750 c, t dbSNP:755235455
1755 1755 -, g dbSNP:35916714
1755 1755 c, t dbSNP:750978297
1760 1760 a, g dbSNP:779107107
1767 1767 c, t dbSNP:370199906
1786 1786 c, t dbSNP:772426240
1794 1794 c, t dbSNP:183429673
1803 1803 a, g dbSNP:551830455
1819 1819 c, g dbSNP:576581168
1860 1860 g, t dbSNP:568563514
1936 1936 c, g dbSNP:753848729

Target ORF information:

RefSeq Version NM_001111045
Organism Homo sapiens (human)
Definition Homo sapiens cyclin A1 (CCNA1), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001111045

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
ATGGAGACCG GCTTTCCCGC AATCATGTAC CCTGGATCTT TTATTGGGGG CTGGGGAGAA 
GAGTATCTCA GCTGGGAAGG ACCGGGGCTC CCAGATTTCG TCTTCCAGCA GCCCGTGGAG
TCTGAAGCAA TGCACTGCAG CAACCCCAAG AGTGGAGTTG TGCTGGCTAC AGTGGCCCGA
GGTCCCGATG CTTGTCAGAT ACTCACCAGA GCCCCGCTGG GCCAGGATCC CCCGCAGAGG
ACAGTGCTAG GGCTGCTAAC TGCAAATGGG CAGTACAGGA GGACCTGTGG CCAGGGGATC
ACAAGAATCA GGTGTTATTC TGGATCAGAA AATGCCTTCC CTCCAGCTGG AAAGAAAGCA
CTCCCTGACT GTGGGGTCCA AGAGCCCCCC AAGCAAGGGT TTGACATCTA CATGGATGAA
CTAGAGCAGG GGGACAGAGA CAGCTGCTCG GTCAGAGAGG GGATGGCATT TGAGGATGTG
TATGAAGTAG ACACCGGCAC ACTCAAGTCA GACCTGCACT TCCTGCTGGA TTTCAACACA
GTTTCCCCTA TGCTGGTAGA TTCATCTCTC CTCTCCCAGT CTGAAGATAT ATCCAGTCTT
GGCACAGATG TGATAAATGT GACTGAATAT GCTGAAGAAA TTTATCAGTA CCTTAGGGAA
GCTGAAATAA GGCACAGACC CAAAGCACAC TACATGAAGA AGCAGCCAGA CATCACGGAA
GGCATGCGCA CGATTCTGGT GGACTGGCTG GTGGAGGTTG GGGAAGAATA TAAACTTCGA
GCAGAGACCC TGTATCTGGC TGTCAACTTC CTGGACAGGT TCCTTTCATG TATGTCTGTT
CTGAGAGGGA AACTGCAGCT CGTAGGAACA GCAGCTATGC TTTTGGCTTC GAAATATGAA
GAGATATATC CTCCTGAAGT AGACGAGTTT GTCTATATCA CCGATGATAC ATACACAAAA
CGACAACTGT TAAAAATGGA ACACTTGCTT CTGAAAGTTC TAGCTTTTGA TCTGACAGTA
CCAACCACCA ACCAGTTTCT CCTTCAGTAC TTGAGGCGAC AAGGAGTGTG CGTCAGGACT
GAGAACCTGG CTAAGTACGT AGCAGAGCTG AGTCTACTTG AAGCAGATCC ATTCTTGAAA
TATCTTCCTT CACTGATAGC TGCAGCAGCT TTTTGCCTGG CAAACTATAC TGTGAACAAG
CACTTTTGGC CAGAAACCCT TGCTGCATTT ACAGGGTATT CATTAAGTGA AATTGTGCCT
TGCCTGAGTG AGCTTCATAA AGCGTACCTT GATATACCCC ATCGACCTCA GCAAGCAATT
AGGGAGAAGT ACAAGGCTTC AAAGTACCTG TGTGTGTCCC TCATGGAGCC ACCTGCAGTT
CTTCTTCTAC AATAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu25352
Accession Version NM_001111046.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1266bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product cyclin-A1 isoform c
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BG723613.1, AL359767.13, CD171793.1, U66838.1 and AA553454.1. Summary: The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. The cyclin encoded by this gene was shown to be expressed in testis and brain, as well as in several leukemic cell lines, and is thought to primarily function in the control of the germline meiotic cell cycle. This cyclin binds both CDK2 and CDC2 kinases, which give two distinct kinase activities, one appearing in S phase, the other in G2, and thus regulate separate functions in cell cycle. This cyclin was found to bind to important cell cycle regulators, such as Rb family proteins, transcription factor E2F-1, and the p21 family proteins. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]. Transcript Variant: This variant (3) contains a distinct 5' UTR and lacks an in-frame portion of the 5' coding region, compared to variant 1. Transcript variants 3 and 4 encode isoform c, which has a shorter N-terminus when compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK301897.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2145313 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
ATGCACTGCA GCAACCCCAA GAGTGGAGTT GTGCTGGCTA CAGTGGCCCG AGGTCCCGAT 
GCTTGTCAGA TACTCACCAG AGCCCCGCTG GGCCAGGATC CCCCGCAGAG GACAGTGCTA
GGGCTGCTAA CTGCAAATGG GCAGTACAGG AGGACCTGTG GCCAGGGGAT CACAAGAATC
AGGTGTTATT CTGGATCAGA AAATGCCTTC CCTCCAGCTG GAAAGAAAGC ACTCCCTGAC
TGTGGGGTCC AAGAGCCCCC CAAGCAAGGG TTTGACATCT ACATGGATGA ACTAGAGCAG
GGGGACAGAG ACAGCTGCTC GGTCAGAGAG GGGATGGCAT TTGAGGATGT GTATGAAGTA
GACACCGGCA CACTCAAGTC AGACCTGCAC TTCCTGCTGG ATTTCAACAC AGTTTCCCCT
ATGCTGGTAG ATTCATCTCT CCTCTCCCAG TCTGAAGATA TATCCAGTCT TGGCACAGAT
GTGATAAATG TGACTGAATA TGCTGAAGAA ATTTATCAGT ACCTTAGGGA AGCTGAAATA
AGGCACAGAC CCAAAGCACA CTACATGAAG AAGCAGCCAG ACATCACGGA AGGCATGCGC
ACGATTCTGG TGGACTGGCT GGTGGAGGTT GGGGAAGAAT ATAAACTTCG AGCAGAGACC
CTGTATCTGG CTGTCAACTT CCTGGACAGG TTCCTTTCAT GTATGTCTGT TCTGAGAGGG
AAACTGCAGC TCGTAGGAAC AGCAGCTATG CTTTTGGCTT CGAAATATGA AGAGATATAT
CCTCCTGAAG TAGACGAGTT TGTCTATATC ACCGATGATA CATACACAAA ACGACAACTG
TTAAAAATGG AACACTTGCT TCTGAAAGTT CTAGCTTTTG ATCTGACAGT ACCAACCACC
AACCAGTTTC TCCTTCAGTA CTTGAGGCGA CAAGGAGTGT GCGTCAGGAC TGAGAACCTG
GCTAAGTACG TAGCAGAGCT GAGTCTACTT GAAGCAGATC CATTCTTGAA ATATCTTCCT
TCACTGATAG CTGCAGCAGC TTTTTGCCTG GCAAACTATA CTGTGAACAA GCACTTTTGG
CCAGAAACCC TTGCTGCATT TACAGGGTAT TCATTAAGTG AAATTGTGCC TTGCCTGAGT
GAGCTTCATA AAGCGTACCT TGATATACCC CATCGACCTC AGCAAGCAAT TAGGGAGAAG
TACAAGGCTT CAAAGTACCT GTGTGTGTCC CTCATGGAGC CACCTGCAGT TCTTCTTCTA
CAATAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeqNP_001104516.1
CDS362..1627
Misc Feature(1)956..1225(+)
Misc Feature(2)956..1090(+)
Misc Feature(3)1112..1213(+)
Misc Feature(4)1247..1510(+)
Misc Feature(5)1247..1384(+)
Misc Feature(6)1406..1498(+)
Exon (1)1..337
Gene:CCNA1
Gene Synonym:
Exon (2)338..526
Gene:CCNA1
Gene Synonym:
Exon (3)527..773
Gene:CCNA1
Gene Synonym:
Exon (4)774..898
Gene:CCNA1
Gene Synonym:
Exon (5)899..1122
Gene:CCNA1
Gene Synonym:
Exon (6)1123..1327
Gene:CCNA1
Gene Synonym:
Exon (7)1328..1441
Gene:CCNA1
Gene Synonym:
Exon (8)1442..1575
Gene:CCNA1
Gene Synonym:
Exon (9)1576..1844
Gene:CCNA1
Gene Synonym:
Translation
Position Chain Variation Link
101 101 -, gg dbSNP:139049981
240 240 c, g dbSNP:113328220
292 292 g, t dbSNP:553662173
301 301 c, t dbSNP:571993725
343 343 c, g dbSNP:141476503
352 352 a, g dbSNP:755391943
361 361 a, g dbSNP:779524233
367 367 c, t dbSNP:147007878
370 370 -, cagcaa dbSNP:763106197
373 373 c, g, t dbSNP:377589059
378 378 c, t dbSNP:142133640
379 379 c, t dbSNP:151081377
382 382 a, g dbSNP:746609003
384 384 a, g dbSNP:145220476
390 390 c, t dbSNP:560118670
401 401 a, g dbSNP:370964964
403 403 a, g dbSNP:759393578
407 407 a, g dbSNP:769594081
418 418 c, t dbSNP:149125997
423 423 c, t dbSNP:761793251
427 427 c, t dbSNP:767691805
431 431 a, t dbSNP:368007173
440 440 a, g dbSNP:143296005
446 446 c, g dbSNP:370590641
447 447 c, g dbSNP:760912284
455 455 c, t dbSNP:766731424
456 456 a, g dbSNP:754232617
457 457 c, g dbSNP:540233147
461 461 c, g, t dbSNP:552343736
464 464 c, t dbSNP:753307734
465 465 a, c dbSNP:746200537
466 466 a, g dbSNP:758844418
472 472 a, g dbSNP:201226091
478 478 a, g dbSNP:148316727
500 500 a, g dbSNP:746557549
537 537 a, g dbSNP:751042420
539 539 a, g dbSNP:756797263
541 541 c, g dbSNP:780816141
542 542 a, t dbSNP:575517029
544 544 a, g dbSNP:772777206
547 547 c, t dbSNP:779831451
550 550 c, t dbSNP:61729896
575 575 c, t dbSNP:768692826
576 576 c, t dbSNP:774471192
579 579 c, g, t dbSNP:747082248
592 592 a, g dbSNP:145829125
607 607 a, g dbSNP:759740467
608 608 g, t dbSNP:765412925
610 610 a, c dbSNP:775879131
611 611 c, g dbSNP:763352839
616 616 -, c dbSNP:777748261
616 616 a, g dbSNP:764550152
617 617 c, g, t dbSNP:574280988
618 618 c, g dbSNP:367588569
619 619 a, c dbSNP:749904346
621 621 c, g dbSNP:755751093
631 631 a, g, t dbSNP:779594513
644 644 a, g dbSNP:754888442
654 654 a, t dbSNP:61733784
662 662 a, g dbSNP:371431411
665 665 g, t dbSNP:748042719
673 673 c, t dbSNP:772143355
681 681 c, t dbSNP:143100244
682 682 a, g, t dbSNP:368505689
684 684 c, t dbSNP:765937307
686 686 -, ag dbSNP:753784627
687 687 a, g dbSNP:540179877
692 692 a, g dbSNP:763296052
693 693 g, t dbSNP:769065045
696 696 c, t dbSNP:113260257
704 704 a, g dbSNP:199835821
711 711 a, t dbSNP:374907767
712 712 a, g dbSNP:767940034
718 718 a, g dbSNP:753412232
721 721 a, g dbSNP:760144028
727 727 c, t dbSNP:766051820
728 728 a, g dbSNP:753604464
734 734 c, t dbSNP:754694176
737 737 a, g dbSNP:368185225
745 745 c, t dbSNP:201364984
748 748 a, g dbSNP:758365529
750 750 a, g dbSNP:777624140
768 768 a, g dbSNP:200724447
769 769 c, t dbSNP:769827681
770 770 a, g dbSNP:780306675
772 772 a, g dbSNP:749452494
777 777 c, t dbSNP:778026294
782 782 a, g dbSNP:757229441
786 786 c, t dbSNP:780039232
787 787 a, g dbSNP:749399552
790 790 a, g dbSNP:755143850
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1001 1001 c, t dbSNP:774093184
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1120 1120 a, t dbSNP:150705387
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1500 1500 c, g dbSNP:140628294
1509 1509 a, g dbSNP:774789693
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1524 1524 a, t dbSNP:772784183
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1611 1611 -, ttc dbSNP:773213910
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1621 1621 a, g