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HIST1H2AG cDNA ORF clone, Homo sapiens (human)

Gene Symbol HIST1H2AG
Entrez Gene ID 8969
Full Name histone cluster 1, H2ag
Synonyms H2A.1b, H2A/p, H2AFP, H2AG, pH2A/f
General protein information
Preferred Names
histone H2A type 1
Names
histone H2A type 1
H2A.1
histone H2A/p
histone 1, H2ag
H2A histone family, member P
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

6

6p22.1

Summary Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2A family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the histone microcluster on chromosome 6p21.33. [provided by RefSeq, Aug 2015]. lac of sum
Disorder MIM:

615012


mRNA and Protein(s)

mRNA Protein Name
NM_021064 NP_066408 histone H2A type 1



Homo sapiens (human) HIST1H2AG NP_066408.1
Pan troglodytes (chimpanzee) LOC736529 XP_003311177.1
Macaca mulatta (Rhesus monkey) HIST1H2AK XP_001095673.1
Canis lupus familiaris (dog) LOC488297 XP_545419.1
Bos taurus (cattle) LOC529277 XP_005223785.1
Mus musculus (house mouse) Hist1h2an NP_835491.1
Rattus norvegicus (Norway rat) Hist1h2ai XP_577577.1


The following HIST1H2AG gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the HIST1H2AG cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu16513
NM_021064 Homo sapiens histone cluster 1, H2ag (HIST1H2AG), mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$49.50-$69.30
$99.00
Next-day Shipping ORF Clones ( in default vector with tag)
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*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu16513
Clone ID Related Accession (Same CDS sequence) NM_021064
Accession Version NM_021064.4 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 393bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 18-AUG-2015
Organism Homo sapiens (human)
Product histone H2A type 1
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK312124.1 and BC016677.1. On Apr 25, 2009 this sequence version replaced gi:38570130. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##RefSeq-Attributes-START## replication-dependent histone :: PMID: 12408966 ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
ATGTCTGGAC GTGGCAAGCA GGGAGGCAAA GCCCGCGCTA AGGCCAAGAC TCGCTCTTCT 
AGGGCCGGTC TCCAGTTCCC CGTGGGCCGA GTGCACCGCC TGCTCCGCAA AGGCAACTAT
GCCGAGCGGG TCGGGGCCGG CGCGCCGGTG TATCTGGCAG CGGTGCTGGA GTACCTGACC
GCCGAGATCC TGGAACTGGC GGGCAACGCG GCCCGCGACA ACAAGAAGAC CCGCATCATC
CCGCGTCATC TCCAACTGGC CATCCGCAAC GACGAGGAGC TCAACAAGCT GCTGGGCAAA
GTCACCATCG CACAGGGCGG TGTCCTGCCC AACATTCAGG CCGTGCTACT GCCCAAAAAG
ACTGAGAGCC ACCACAAGGC GAAGGGCAAG TAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_066408.1
CDS35..427
Misc Feature(1)20..22(+)
Misc Feature(2)35..424(+)
Misc Feature(3)38..40(+)
Misc Feature(4)38..40(+)
Misc Feature(5)44..46(+)
Misc Feature(6)44..46(+)
Misc Feature(7)50..394(+)
Misc Feature(8)50..64(+)
Misc Feature(9)50..52(+)
Misc Feature(10)122..268(+)
Misc Feature(11)143..145(+)
Misc Feature(12)149..160(+)
Misc Feature(13)188..226(+)
Misc Feature(14)347..349(+)
Misc Feature(15)389..391(+)
Misc Feature(16)392..394(+)
Misc Feature(17)392..394(+)
Misc Feature(18)395..397(+)
Misc Feature(19)401..403(+)
Misc Feature(20)410..412(+)
Exon (1)1..498
Gene:HIST1H2AG
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_021064
Organism Homo sapiens (human)
Definition Homo sapiens histone cluster 1, H2ag (HIST1H2AG), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_021064

ORF Insert Sequence:

1
61
121
181
241
301
361
ATGTCTGGAC GTGGCAAGCA GGGAGGCAAA GCCCGCGCTA AGGCCAAGAC TCGCTCTTCT 
AGGGCCGGTC TCCAGTTCCC CGTGGGCCGA GTGCACCGCC TGCTCCGCAA AGGCAACTAT
GCCGAGCGGG TCGGGGCCGG CGCGCCGGTG TATCTGGCAG CGGTGCTGGA GTACCTGACC
GCCGAGATCC TGGAACTGGC GGGCAACGCG GCCCGCGACA ACAAGAAGAC CCGCATCATC
CCGCGTCATC TCCAACTGGC CATCCGCAAC GACGAGGAGC TCAACAAGCT GCTGGGCAAA
GTCACCATCG CACAGGGCGG TGTCCTGCCC AACATTCAGG CCGTGCTACT GCCCAAAAAG
ACTGAGAGCC ACCACAAGGC GAAGGGCAAG TAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

book

Structural insights into recognition of acetylated histone ligands by the BRPF1 bromodomain
FEBS Lett. 588 (21), 3844-3854 (2014)
Lubula MY, Eckenroth BE, Carlson S, Poplawski A, Chruszcz M and Glass KC.


book

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine
Proteomics 13 (10-11), 1667-1671 (2013)
Principe S, Jones EE, Kim Y, Sinha A, Nyalwidhe JO, Brooks J, Semmes OJ, Troyer DA, Lance RS, Kislinger T and Drake RR.


book

Macro histone H2A1.2 (macroH2A1) protein suppresses mitotic kinase VRK1 during interphase
J. Biol. Chem. 287 (8), 5278-5289 (2012)
Kim W, Chakraborty G, Kim S, Shin J, Park CH, Jeong MW, Bharatham N, Yoon HS and Kim KT.


book

Proteomic characterization of the human sperm nucleus
Proteomics 11 (13), 2714-2726 (2011)
de Mateo S, Castillo J, Estanyol JM, Ballesca JL and Oliva R.


book

Proteomic and biochemical analysis of 14-3-3-binding proteins during C2-ceramide-induced apoptosis
FEBS J. 277 (16), 3321-3342 (2010)
Pozuelo-Rubio M.


book

The human and mouse replication-dependent histone genes
Genomics 80 (5), 487-498 (2002)
Marzluff WF, Gongidi P, Woods KR, Jin J and Maltais LJ.


book

The human H2A and H2B histone gene complement
Biol. Chem. 380 (1), 7-18 (1999)
Albig W, Trappe R, Kardalinou E, Eick S and Doenecke D.


book

Transcriptional activation of the integrated chromatin-associated human immunodeficiency virus type 1 promoter
Mol. Cell. Biol. 18 (5), 2535-2544 (1998)
El Kharroubi A, Piras G, Zensen R and Martin MA.


book

The human histone gene cluster at the D6S105 locus
Hum. Genet. 101 (3), 284-294 (1997)
Albig W and Doenecke D.


book

The relative expression of human histone H2A genes is similar in different types of proliferating cells
DNA Cell Biol. 13 (2), 161-170 (1994)
Mannironi C, Orr A, Hatch C, Pilch D, Ivanova V and Bonner W.


 
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