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EXOC3L2 cDNA ORF clone, Homo sapiens (human)

Gene Symbol EXOC3L2
Entrez Gene ID 90332
Full Name exocyst complex component 3-like 2
Synonyms XTP7
General protein information
Preferred Names
exocyst complex component 3-like protein 2
Names
exocyst complex component 3-like protein 2
HBV XAg-transactivated protein 7
HBV X-transactivated gene 7 protein
protein 7 transactivated by hepatitis B virus X antigen (HBxAg)
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

19

19q13.32

Summary lac of sum

mRNA and Protein(s)

mRNA Protein Name
NM_138568 NP_612635 exocyst complex component 3-like protein 2


Homo sapiens (human) EXOC3L2 NP_612635.3
Pan troglodytes (chimpanzee) EXOC3L2 XP_512744.4
Canis lupus familiaris (dog) EXOC3L2 XP_541565.2
Bos taurus (cattle) EXOC3L2 XP_002695139.2
Mus musculus (house mouse) Exoc3l2 XP_006540538.1
Rattus norvegicus (Norway rat) Exoc3l2 XP_006228560.1
Danio rerio (zebrafish) LOC565839 XP_694193.4
Danio rerio (zebrafish) exoc3l2a XP_683981.5
Xenopus (Silurana) tropicalis (western clawed frog) LOC100486119 XP_002932652.2


GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following EXOC3L2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the EXOC3L2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu24148
NM_138568 Homo sapiens exocyst complex component 3-like 2 (EXOC3L2), mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
Starting from $189.50
$379.00

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu24148
Clone ID Related Accession (Same CDS sequence) NM_138568
Accession Version NM_138568.3 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1230bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product exocyst complex component 3-like protein 2
Comment VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK093466.1, BC104947.1 and AA069926.1. On Apr 4, 2009 this sequence version replaced gi:29788775. ##Evidence-Data-START## Transcript exon combination :: AK093466.1, AK225791.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
ATGGCCGCCC TGGAGAATGG GGAGCTGGGG CCCCTTCTCT CCCCTGGCAC CCTGCGGGGT 
TTGGAGGATG AATGCGTCAC AGATGTTAAG GCTCAGACCC GGGCTGCCCT TCTCCGTGTG
CTGCAGGAGG ACGAAGAGCA CTGGGGGAGC CTGGAGGACC AGCCCAGCAG CCTGGCCCAG
GATGTGTGTG AGCTGCTGGA AGAGCACACA GAGCGAGCAC CCCGCATCAG CCAGGAGTTT
GGGGAGCGGA TGGCCCACTG CTGCCTAGGC GGGCTGGCAG AGTTCCTGCA GAGCTTCCAG
CAGCGTGTGG AGCGATTCCA TGAGAACCCA GCAGTCCGGG AGATGCTACC TGACACCTAT
ATCAGCAAGA CCATCGCCCT GGTCAACTGC GGCCCCCCAC TGAGAGCTCT GGCCGAGCGC
CTGGCCCGGG TGGGGCCCCC AGAAAGCGAG CCGGCCCGGG AAGCATCTGC TAGTGCTCTG
GACCATGTGA CCCGGCTCTG CCACCGTGTC GTGGCCAACC TGCTGTTCCA GGAGCTGCAG
CCACACTTCA ACAAGCTGAT GCGCCGGAAG TGGCTGAGCA GCCCGGAGGC CCTGGATGGC
ATCGTGGGCA CGCTGGGTGC CCAGGCCCTG GCCCTGCGCA GAATGCAGGA CGAGCCTTAC
CAGGCGCTGG TAGCCGAGCT ACACCGGCGG GCGCTGGTCG AGTACGTGCG GCCCCTGCTC
CGTGGGCGCC TGCGCTGCAG CTCGGCGCGG ACCCGCAGCC GCGTGGCCGG CAGGCTCCGG
GAGGACGCGG CGCAACTGCA GAGGCTGTTC CGGCGGCTGG AGTCCCAGGC CTCGTGGCTG
GATGCCGTGG TGCCCCATTT GGCTGAAGTC ATGCAGCTGG AAGACACGCC CAGCATCCAG
GTGGAGGTGG GAGTGTTGGT GCGCGACTAC CCAGACATCA GGCAGAAGCA CGTGGCAGCC
CTCCTCGACA TCCGTGGCCT GCGCAACACA GCCGCCCGCC AGGAGATCCT GGCCGTGGCC
CGGGACCTGG AACTCTCTGA GGAGGGAGCC CTGTCACCCC CTCGGGACCG TGCCTTCTTT
GCAGACATCC CTGTGCCCCG CCCATCTTTC TGTCTCAGCC TCCCTCTCTT CCTGGGCCGC
CTCCCCCTCT CCCGGCTGGC CAGGCCCAGT TTGGCCTGTC TGCCTCGGCC CCGGCCTCCG
TCTCTAGCGC GACCTCGGGC CCAGCGCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_612635.3
CDS42..1271
Misc Feature(1)63..1106(+)
Exon (1)1..19
Gene:EXOC3L2
Gene Synonym:
Exon (2)20..131
Gene:EXOC3L2
Gene Synonym:
Exon (3)132..233
Gene:EXOC3L2
Gene Synonym:
Exon (4)234..334
Gene:EXOC3L2
Gene Synonym:
Exon (5)335..445
Gene:EXOC3L2
Gene Synonym:
Exon (6)446..581
Gene:EXOC3L2
Gene Synonym:
Exon (7)582..704
Gene:EXOC3L2
Gene Synonym:
Exon (8)705..860
Gene:EXOC3L2
Gene Synonym:
Exon (9)861..982
Gene:EXOC3L2
Gene Synonym:
Exon (10)983..1719
Gene:EXOC3L2
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_138568
Organism Homo sapiens (human)
Definition Homo sapiens exocyst complex component 3-like 2 (EXOC3L2), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_138568

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
ATGGCCGCCC TGGAGAATGG GGAGCTGGGG CCCCTTCTCT CCCCTGGCAC CCTGCGGGGT 
TTGGAGGATG AATGCGTCAC AGATGTTAAG GCTCAGACCC GGGCTGCCCT TCTCCGTGTG
CTGCAGGAGG ACGAAGAGCA CTGGGGGAGC CTGGAGGACC AGCCCAGCAG CCTGGCCCAG
GATGTGTGTG AGCTGCTGGA AGAGCACACA GAGCGAGCAC CCCGCATCAG CCAGGAGTTT
GGGGAGCGGA TGGCCCACTG CTGCCTAGGC GGGCTGGCAG AGTTCCTGCA GAGCTTCCAG
CAGCGTGTGG AGCGATTCCA TGAGAACCCA GCAGTCCGGG AGATGCTACC TGACACCTAT
ATCAGCAAGA CCATCGCCCT GGTCAACTGC GGCCCCCCAC TGAGAGCTCT GGCCGAGCGC
CTGGCCCGGG TGGGGCCCCC AGAAAGCGAG CCGGCCCGGG AAGCATCTGC TAGTGCTCTG
GACCATGTGA CCCGGCTCTG CCACCGTGTC GTGGCCAACC TGCTGTTCCA GGAGCTGCAG
CCACACTTCA ACAAGCTGAT GCGCCGGAAG TGGCTGAGCA GCCCGGAGGC CCTGGATGGC
ATCGTGGGCA CGCTGGGTGC CCAGGCCCTG GCCCTGCGCA GAATGCAGGA CGAGCCTTAC
CAGGCGCTGG TAGCCGAGCT ACACCGGCGG GCGCTGGTCG AGTACGTGCG GCCCCTGCTC
CGTGGGCGCC TGCGCTGCAG CTCGGCGCGG ACCCGCAGCC GCGTGGCCGG CAGGCTCCGG
GAGGACGCGG CGCAACTGCA GAGGCTGTTC CGGCGGCTGG AGTCCCAGGC CTCGTGGCTG
GATGCCGTGG TGCCCCATTT GGCTGAAGTC ATGCAGCTGG AAGACACGCC CAGCATCCAG
GTGGAGGTGG GAGTGTTGGT GCGCGACTAC CCAGACATCA GGCAGAAGCA CGTGGCAGCC
CTCCTCGACA TCCGTGGCCT GCGCAACACA GCCGCCCGCC AGGAGATCCT GGCCGTGGCC
CGGGACCTGG AACTCTCTGA GGAGGGAGCC CTGTCACCCC CTCGGGACCG TGCCTTCTTT
GCAGACATCC CTGTGCCCCG CCCATCTTTC TGTCTCAGCC TCCCTCTCTT CCTGGGCCGC
CTCCCCCTCT CCCGGCTGGC CAGGCCCAGT TTGGCCTGTC TGCCTCGGCC CCGGCCTCCG
TCTCTAGCGC GACCTCGGGC CCAGCGCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

book

Association between EXOC3L2 rs597668 polymorphism and Alzheimer's disease
CNS Neurosci Ther 19 (10), 834-839 (2013)
Shang H, Fu J, Zhang XM, Song RR and Wang WZ.


book

Lack of association between rs597668 polymorphism near EXOC3L2 and late-onset Alzheimer's disease in Han Chinese
Neurosci. Lett. 513 (2), 174-177 (2012)
Liu QY, Miao D, Yu JT, Xing YY, Zhong XL, Wu ZC, Zhang Q and Tan L.


book

New gene functions in megakaryopoiesis and platelet formation
Nature 480 (7376), 201-208 (2011)
Gieger C, Radhakrishnan A, Cvejic A, Tang W, Porcu E, Pistis G, Serbanovic-Canic J, Elling U, Goodall AH, Labrune Y, Lopez LM, Magi R, Meacham S, Okada Y, Pirastu N, Sorice R, Teumer A, Voss K, Zhang W, Ramirez-Solis R, Bis JC, Ellinghaus D, Gogele M, Hottenga JJ, Langenberg C, Kovacs P, O'Reilly PF, Shin SY, Esko T, Hartiala J, Kanoni S, Murgia F, Parsa A, Stephens J, van der Harst P, Ellen van der Schoot C, Allayee H, Attwood A, Balkau B, Bastardot F, Basu S, Baumeister SE, Biino G, Bomba L, Bonnefond A, Cambien F, Chambers JC, Cucca F, D'Adamo P, Davies G, de Boer RA, de Geus EJ, Doring A, Elliott P, Erdmann J, Evans DM, Falchi M, Feng W, Folsom AR, Frazer IH, Gibson QD, Glazer NL, Hammond C, Hartikainen AL, Heckbert SR, Hengstenberg C, Hersch M, Illig T, Loos RJ, Jolley J, Khaw KT, Kuhnel B, Kyrtsonis MC, Lagou V, Lloyd-Jones H, Lumley T, Mangino M, Maschio A, Mateo Leach I, McKnight B, Memari Y, Mitchell BD, Montgomery GW, Nakamura Y, Nauck M, Navis G, Nothlings U, Nolte IM, Porteous DJ, Pouta A, Pramstaller PP, Pullat J, Ring SM, Rotter JI, Ruggiero D, Ruokonen A, Sala C, Samani NJ, Sambrook J, Schlessinger D, Schreiber S, Schunkert H, Scott J, Smith NL, Snieder H, Starr JM, Stumvoll M, Takahashi A, Tang WH, Taylor K, Tenesa A, Lay Thein S, Tonjes A, Uda M, Ulivi S, van Veldhuisen DJ, Visscher PM, Volker U, Wichmann HE, Wiggins KL, Willemsen G, Yang TP, Hua Zhao J, Zitting P, Bradley JR, Dedoussis GV, Gasparini P, Hazen SL, Metspalu A, Pirastu M, Shuldiner AR, Joost van Pelt L, Zwaginga JJ, Boomsma DI, Deary IJ, Franke A, Froguel P, Ganesh SK, Jarvelin MR, Martin NG, Meisinger C, Psaty BM, Spector TD, Wareham NJ, Akkerman JW, Ciullo M, Deloukas P, Greinacher A, Jupe S, Kamatani N, Khadake J, Kooner JS, Penninger J, Prokopenko I, Stemple D, Toniolo D, Wernisch L, Sanna S, Hicks AA, Rendon A, Ferreira MA, Ouwehand WH and Soranzo N.


book

Exocyst complex component 3-like 2 (EXOC3L2) associates with the exocyst complex and mediates directional migration of endothelial cells
J. Biol. Chem. 286 (27), 24189-24199 (2011)
Barkefors I, Fuchs PF, Heldin J, Bergstrom T, Forsberg-Nilsson K and Kreuger J.


book

Genome-wide analysis of genetic loci associated with Alzheimer disease
JAMA 303 (18), 1832-1840 (2010)
Seshadri S, Fitzpatrick AL, Ikram MA, DeStefano AL, Gudnason V, Boada M, Bis JC, Smith AV, Carassquillo MM, Lambert JC, Harold D, Schrijvers EM, Ramirez-Lorca R, Debette S, Longstreth WT Jr, Janssens AC, Pankratz VS, Dartigues JF, Hollingworth P, Aspelund T, Hernandez I, Beiser A, Kuller LH, Koudstaal PJ, Dickson DW, Tzourio C, Abraham R, Antunez C, Du Y, Rotter JI, Aulchenko YS, Harris TB, Petersen RC, Berr C, Owen MJ, Lopez-Arrieta J, Varadarajan BN, Becker JT, Rivadeneira F, Nalls MA, Graff-Radford NR, Campion D, Auerbach S, Rice K, Hofman A, Jonsson PV, Schmidt H, Lathrop M, Mosley TH, Au R, Psaty BM, Uitterlinden AG, Farrer LA, Lumley T, Ruiz A, Williams J, Amouyel P, Younkin SG, Wolf PA, Launer LJ, Lopez OL, van Duijn CM and Breteler MM.


book

Genome-wide association studies in an isolated founder population from the Pacific Island of Kosrae
PLoS Genet. 5 (2), E1000365 (2009)
Lowe JK, Maller JB, Pe'er I, Neale BM, Salit J, Kenny EE, Shea JL, Burkhardt R, Smith JG, Ji W, Noel M, Foo JN, Blundell ML, Skilling V, Garcia L, Sullivan ML, Lee HE, Labek A, Ferdowsian H, Auerbach SB, Lifton RP, Newton-Cheh C, Breslow JL, Stoffel M, Daly MJ, Altshuler DM and Friedman JM.


 
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