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ISX intestine-specific homeobox [Homo sapiens (human)]

Gene Symbol ISX
Entrez Gene ID 91464
Full Name intestine-specific homeobox
Synonyms Pix-1, RAXLX
General protein information
Preferred Names
intestine-specific homeobox
Names
intestine-specific homeobox
RAX-like homeobox
pancreas-intestine homeodomain transcription factor
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

22

22q12.3

Summary Homeobox genes encode DNA-binding proteins, many of which are thought to be involved in early embryonic development. Homeobox genes encode a DNA-binding domain of 60 to 63 amino acids referred to as the homeodomain. This gene is a member of the RAXLX homeobox gene family. [provided by RefSeq, Jul 2008]. lac of sum
Disorder MIM:

612019

Disorder Html:





The following ISX gene sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ISX gene which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu30776 NM_001303508 Homo sapiens intestine-specific homeobox (ISX), mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $199

*Business Day
**You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.


CloneID OHu30776
Accession Version NM_001303508.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 738bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector Document: User manual_GenEZ ORF Clone Products.pdf (pdf)
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags Document: MSDS_GenEZ ORF Clone Products.pdf (pdf)
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product intestine-specific homeobox
Comment VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CR749372.1, Z83853.2, AL024494.1 and AK025181.1. Summary: Homeobox genes encode DNA-binding proteins, many of which are thought to be involved in early embryonic development. Homeobox genes encode a DNA-binding domain of 60 to 63 amino acids referred to as the homeodomain. This gene is a member of the RAXLX homeobox gene family. [provided by RefSeq, Jul 2008]. ##Evidence-Data-START## Transcript exon combination :: CR749372.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA2142348 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
ATGTGTGCTG AGGTGGGCCC TGCTCTCTGC AGGGGTATGG AGAGAAATAG CTTGGGGTGC 
TGTGAGGCCC CGAAGAAGCT GAGCCTGTCC TTCTCCATTG AGGCGATCCT AAAGAGGCCT
GCCAGGAGGA GTGATATGGA CAGACCAGAA GGGCCAGGTG AAGAGGGCCC CGGAGAAGCT
GCGGCCTCAG GCTCTGGGCT AGAAAAGCCT CCAAAGGACC AGCCCCAGGA AGGAAGGAAG
AGCAAGCGGA GGGTTCGTAC CACCTTCACC ACTGAGCAGC TGCATGAGCT GGAGAAGATC
TTCCACTTTA CCCACTACCC AGACGTTCAC ATCCGCAGCC AGCTGGCAGC CAGGATCAAC
CTCCCAGAAG CTCGGGTGCA GATCTGGTTC CAGAATCAGC GAGCCAAGTG GCGGAAGCAG
GAGAAGATTG GCAACCTGGG GGCTCCACAG CAGCTGAGTG AAGCCAGTGT GGCCCTGCCC
ACAAATCTGG ATGTGGCTGG GCCCACGTGG ACATCCACTG CTCTGCGCAG GCTGGCTCCT
CCCACGAGCT GTTGTCCATC GGCTCAAGAT CAGCTGGCCT CTGCCTGGTT CCCTGCCTGG
ATCACCCTCC TCCCAGCGCA CCCATGGGAA ACACAGCCTG TCCCAGGTCT TCCCATCCAT
CAAACTTGCA TCCCTGTGCT ATGCATCCTT CCACCTCCAC ACCCCAAATG GGGCAGCATC
TGTGCTACTT CAACATAG
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_001290437.1
CDS664..1401
Misc Feature(1)538..540(+)
Misc Feature(2)910..1086(+)
Misc Feature(3)910..1080(+)
Misc Feature(4)916..1068(+)
Exon (1)1..327
Gene:ISX
Gene Synonym:
Exon (2)328..892
Gene:ISX
Gene Synonym:
Exon (3)893..1044
Gene:ISX
Gene Synonym:
Exon (4)1045..1161
Gene:ISX
Gene Synonym:
Exon (5)1162..3095
Gene:ISX
Gene Synonym:
Translation
Position Chain Variation Link
3 3 a, t dbSNP:572323533
8 8 a, c dbSNP:150978788
78 78 a, t dbSNP:374090932
107 107 c, t dbSNP:560825718
121 121 c, t dbSNP:362150
132 132 c, g dbSNP:542734366
138 138 c, t dbSNP:113980101
147 147 a, t dbSNP:549543256
152 152 c, t dbSNP:184523171
237 237 a, g dbSNP:189089225
261 261 c, t dbSNP:140849535
267 267 c, t dbSNP:529412858
272 272 a, g dbSNP:565939426
288 288 a, c dbSNP:534519272
318 318 a, t dbSNP:548362264
329 329 g, t dbSNP:112660672
347 347 c, t dbSNP:370674512
358 358 g, t dbSNP:374102389
369 369 c, t dbSNP:111427997
392 392 c, t dbSNP:574473775
447 447 a, g dbSNP:371845504
450 450 a, g, t dbSNP:563337377
517 517 c, t dbSNP:759847681
547 547 g, t dbSNP:551527296
568 568 c, t dbSNP:77984721
569 569 a, g dbSNP:537154207
570 570 c, t dbSNP:559730650
587 587 c, g dbSNP:769577544
623 623 c, t dbSNP:528377839
630 630 c, t dbSNP:751158163
631 631 g, t dbSNP:761210775
635 635 a, c, g dbSNP:200664733
638 638 -, ac dbSNP:751871829
640 640 a, g dbSNP:755726408
642 642 -, ag dbSNP:757504378
645 645 a, g dbSNP:779160679
649 649 a, c dbSNP:753011847
651 651 a, c dbSNP:758934453
653 653 c, t dbSNP:778219505
657 657 -, c dbSNP:781433854
657 657 c, t dbSNP:747139986
662 662 c, t dbSNP:375532143
664 664 a, g dbSNP:568223951
665 665 -, t dbSNP:750460998
669 669 -, t dbSNP:756143161
682 682 a, c dbSNP:138420595
685 685 a, g, t dbSNP:771088674
686 686 c, t dbSNP:142905734
690 690 -, t dbSNP:778964293
697 697 g, t dbSNP:749062891
698 698 g, t dbSNP:768766123
699 699 c, t dbSNP:774421891
701 701 c, t dbSNP:761457289
702 702 a, g dbSNP:766941980
715 715 c, t dbSNP:772720937
720 720 a, g dbSNP:760268946
721 721 c, t dbSNP:765974800
727 727 a, g dbSNP:753099390
728 728 a, g dbSNP:758740418
731 731 c, t dbSNP:530592366
734 734 c, t dbSNP:752002753
735 735 a, c, g dbSNP:147323979
741 741 c, g dbSNP:745909237
745 745 a, g dbSNP:361863
747 747 c, t dbSNP:780403861
749 749 a, t dbSNP:749157766
750 750 a, g dbSNP:181803035
753 753 -, ctt dbSNP:748009757
762 762 c, t dbSNP:361668
763 763 a, g dbSNP:748050213
767 767 a, c, t dbSNP:199562176
768 768 a, g dbSNP:760200279
770 770 c, t dbSNP:766066792
779 779 a, g dbSNP:201193476
782 782 a, c dbSNP:776251599
794 794 a, g dbSNP:763375063
798 798 c, t dbSNP:61739191
799 799 a, g dbSNP:751889584
801 801 a, g dbSNP:535302186
808 808 c, t dbSNP:61739193
814 814 a, g dbSNP:572764817
821 821 a, g dbSNP:768025436
832 832 c, t dbSNP:362090
835 835 a, g dbSNP:377644750
840 840 a, g dbSNP:780495578
844 844 a, g dbSNP:749529646
845 845 c, t dbSNP:755194255
846 846 a, g, t dbSNP:142318080
847 847 c, g dbSNP:771942217
849 849 c, g dbSNP:777742842
853 853 g, t dbSNP:746558269
856 856 c, t dbSNP:145306030
871 871 a, c dbSNP:776049872
874 874 c, t dbSNP:759196265
892 892 c, g, t dbSNP:769385966
898 898 a, t dbSNP:201102724
900 900 a, g dbSNP:201559969
910 910 a, c, t dbSNP:745340391
911 911 a, g dbSNP:8140287
915 915 g, t dbSNP:374101977
919 919 c, t dbSNP:372031013
920 920 a, g dbSNP:202000999
923 923 c, t dbSNP:773394623
926 926 c, t dbSNP:761287074
932 932 c, t dbSNP:200321013
937 937 a, c, g dbSNP:754013706
948 948 c, t dbSNP:188488954
952 952 c, g dbSNP:549935545
962 962 c, t dbSNP:146866945
963 963 c, t dbSNP:777634496
968 968 a, t dbSNP:751303700
972 972 c, t dbSNP:757214192
974 974 c, t dbSNP:192929768
978 978 a, c dbSNP:368929942
981 981 c, t dbSNP:755648880
987 987 c, t dbSNP:779368908
988 988 a, g, t dbSNP:373068000
996 996 c, t dbSNP:200644238
997 997 c, g, t dbSNP:144398029
998 998 a, g dbSNP:147806898
1003 1003 c, g dbSNP:531161163
1007 1007 g, t dbSNP:765363354
1013 1013 a, c dbSNP:775374435
1014 1014 c, t dbSNP:763254282
1017 1017 a, g dbSNP:764179371
1018 1018 a, t dbSNP:751393633
1019 1019 c, t dbSNP:757021851
1022 1022 a, c, g dbSNP:767512747
1026 1026 c, t dbSNP:140599630
1027 1027 c, g dbSNP:200067062
1028 1028 a, c dbSNP:748706716
1030 1030 a, g dbSNP:754700932
1033 1033 c, g dbSNP:778687097
1037 1037 a, g dbSNP:570030565
1039 1039 a, g dbSNP:771415858
1063 1063 c, g, t dbSNP:370332592
1064 1064 a, g dbSNP:144899858
1065 1065 a, g dbSNP:374160195
1066 1066 a, g dbSNP:764851237
1069 1069 a, t dbSNP:191515527
1075 1075 a, c, t dbSNP:758150909
1076 1076 a, g dbSNP:184840753
1077 1077 a, g dbSNP:372007711
1082 1082 -, agg dbSNP:777506998
1082 1082 a, g dbSNP:780401029
1091 1091 c, t dbSNP:201106092
1097 1097 a, g dbSNP:574347766
1105 1105 a, g dbSNP:779000065
1106 1106 c, t dbSNP:748195184
1111 1111 c, t dbSNP:772330123
1134 1134 c, g dbSNP:773294360
1136 1136 a, c, t dbSNP:7291048
1141 1141 c, t dbSNP:145896632
1145 1145 a, c dbSNP:776427823
1150 1150 a, c dbSNP:557180558
1152 1152 c, g dbSNP:375729047
1159 1159 a, g dbSNP:368370719
1160 1160 c, t dbSNP:376354873
1164 1164 a, g dbSNP:773864886
1169 1169 c, t dbSNP:377316654
1170 1170 a, g, t dbSNP:199896807
1175 1175 a, c, t dbSNP:754255223
1176 1176 a, c dbSNP:151122186
1177 1177 c, t dbSNP:780042858
1189 1189 a, c, t dbSNP:536678640
1190 1190 a, g dbSNP:777734463
1194 1194 g, t dbSNP:557242882
1197 1197 c, g dbSNP:757456107
1202 1202 a, c dbSNP:781453107
1204 1204 c, t dbSNP:745715406
1206 1206 a, c dbSNP:769706935
1208 1208 a, c, t dbSNP:61735502
1209 1209 a, g dbSNP:749261613
1219 1219 c, t dbSNP:768599663
1220 1220 c, t dbSNP:182078320
1223 1223 c, t dbSNP:200292559
1224 1224 a, g, t dbSNP:202084562
1226 1226 c, g dbSNP:552799717
1255 1255 c, t dbSNP:141032770
1259 1259 a, c dbSNP:781703150
1261 1261 c, t dbSNP:763398623
1272 1272 c, t dbSNP:764626933
1275 1275 c, t dbSNP:376456588
1279 1279 a, g dbSNP:141371935
1280 1280 c, t dbSNP:781335236
1281 1281 a, g, t dbSNP:750677233
1282 1282 c, t dbSNP:780027391
1286 1286 c, t dbSNP:749060872
1288 1288 a, t dbSNP:572709197
1305 1305 c, t dbSNP:778900982
1306 1306 c, g dbSNP:371371714
1315 1315 c, t dbSNP:771619655
1316 1316 a, c dbSNP:748517303
1317 1317 c, t dbSNP:772654042
1320 1320 c, t dbSNP:760339174
1326 1326 a, c dbSNP:770527363
1333 1333 a, g dbSNP:775868404
1345 1345 c, t dbSNP:763349400
1351 1351 c, t dbSNP:267606235
1357 1357 c, t dbSNP:764566112
1360 1360 c, g dbSNP:752101649
1368 1368 a, c dbSNP:762159101
1374 1374 c, g dbSNP:767717609
1375 1375 a, g, t dbSNP:200613012
1376 1376 g, t dbSNP:61735036
1377 1377 a, c dbSNP:753634653
1382 1382 c, t dbSNP:754803028
1390 1390 a, g dbSNP:778509922
1391 1391 c, g dbSNP:748133240
1393 1393 a, t dbSNP:771858332
1396 1396 a, g dbSNP:777293072
1398 1398 a, g dbSNP:372290979
1402 1402 a, g, t dbSNP:770615281
1404 1404 a, t dbSNP:371093171
1408 1408 c, g dbSNP:375463996
1414 1414 c, t dbSNP:773636127
1419 1419 c, t dbSNP:370209016
1421 1421 c, t dbSNP:768108484
1426 1426 a, g dbSNP:185116560
1444 1444 c, g dbSNP:760824365
1445 1445 g, t dbSNP:766778483
1467 1467 a, c dbSNP:543486282
1468 1468 c, t dbSNP:745441264
1491 1491 c, t dbSNP:3810619
1497 1497 a, g dbSNP:372266660
1511 1511 c, g dbSNP:553212559
1535 1535 c, t dbSNP:189872702
1568 1568 c, g dbSNP:546529767
1620 1620 c, t dbSNP:560080417
1624 1624 a, g dbSNP:141018696
1646 1646 a, g dbSNP:775088457
1656 1656 c, t dbSNP:760309316
1661 1661 g, t dbSNP:548741976
1708 1708 g, t dbSNP:144831614
1723 1723 a, g dbSNP:530648826
1725 1725 a, c, t dbSNP:147940646
1726 1726 a, g dbSNP:183126236
1767 1767 a, g dbSNP:546527320
1791 1791 c, t dbSNP:761655546
1792 1792 a, g dbSNP:764884203
1812 1812 c, g dbSNP:750236687
1823 1823 a, g dbSNP:545006027
1829 1829 a, g dbSNP:141223769
1832 1832 c, g dbSNP:574998226
1835 1835 a, g dbSNP:535317957
1837 1837 a, t dbSNP:751619363
1850 1850 a, g dbSNP:555522044
1862 1862 a, g dbSNP:112374826
1871 1871 a, g dbSNP:543900145
1900 1900 a, g dbSNP:186450254
2012 2012 g, t dbSNP:137886754
2026 2026 c, t dbSNP:781722633
2033 2033 a, g dbSNP:766730700
2047 2047 a, g dbSNP:577352020
2049 2049 a, g dbSNP:754384585
2057 2057 c, t dbSNP:753205062
2059 2059 c, t dbSNP:563580730
2104 2104 a, t dbSNP:756645904
2139 2139 g, t dbSNP:113248574
2153 2153 c, t dbSNP:777955726
2158 2158 c, t dbSNP:546216974
2159 2159 a, g dbSNP:553731755
2192 2192 a, g dbSNP:777262469
2213 2213 c, t dbSNP:573469318
2220 2220 c, t dbSNP:542126570
2226 2226 c, t dbSNP:374866722
2232 2232 a, t dbSNP:771824817
2239 2239 a, g dbSNP:562331737
2245 2245 c, g dbSNP:779892165
2298 2298 c, t dbSNP:73410194
2326 2326 a, c dbSNP:149036576
2347 2347 g, t dbSNP:563827547
2399 2399 c, g, t dbSNP:532808353
2459 2459 a, g dbSNP:8142871
2466 2466 c, g dbSNP:566687515
2473 2473 c, t dbSNP:529204130
2484 2484 a, g dbSNP:143172492
2516 2516 c, t dbSNP:569035827
2523 2523 a, c, t dbSNP:776218187
2527 2527 a, c dbSNP:769802491
2554 2554 a, g dbSNP:375077652
2562 2562 a, g dbSNP:537636279
2570 2570 a, g dbSNP:557538715
2579 2579 g, t dbSNP:570936635
2609 2609 c, t dbSNP:539876966
2622 2622 c, g dbSNP:762787081
2636 2636 -, a dbSNP:374687136
2725 2725 c, g dbSNP:542978011
2737 2737 g, t dbSNP:74597006
2741 2741 a, g dbSNP:540716813
2755 2755 a, c dbSNP:751848310
2781 2781 a, t dbSNP:573130731
2784 2784 c, t dbSNP:369440536
2788 2788 c, t dbSNP:759603103
2806 2806 g, t dbSNP:148274521
2825 2825 c, t dbSNP:555745710
2871 2871 a, g dbSNP:78515170
2918 2918 a, t dbSNP:544395022
2950 2950 a, g dbSNP:745606210
3023 3023 g, t dbSNP:752849558
3039 3039 a, c dbSNP:372954879
3055 3055 a, g dbSNP:563864405
3056 3056 c, t dbSNP:532846969

Target ORF information:

RefSeq Version NM_001303508
Organism Homo sapiens (human)
Definition Homo sapiens intestine-specific homeobox (ISX), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001303508

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
ATGTGTGCTG AGGTGGGCCC TGCTCTCTGC AGGGGTATGG AGAGAAATAG CTTGGGGTGC 
TGTGAGGCCC CGAAGAAGCT GAGCCTGTCC TTCTCCATTG AGGCGATCCT AAAGAGGCCT
GCCAGGAGGA GTGATATGGA CAGACCAGAA GGGCCAGGTG AAGAGGGCCC CGGAGAAGCT
GCGGCCTCAG GCTCTGGGCT AGAAAAGCCT CCAAAGGACC AGCCCCAGGA AGGAAGGAAG
AGCAAGCGGA GGGTTCGTAC CACCTTCACC ACTGAGCAGC TGCATGAGCT GGAGAAGATC
TTCCACTTTA CCCACTACCC AGACGTTCAC ATCCGCAGCC AGCTGGCAGC CAGGATCAAC
CTCCCAGAAG CTCGGGTGCA GATCTGGTTC CAGAATCAGC GAGCCAAGTG GCGGAAGCAG
GAGAAGATTG GCAACCTGGG GGCTCCACAG CAGCTGAGTG AAGCCAGTGT GGCCCTGCCC
ACAAATCTGG ATGTGGCTGG GCCCACGTGG ACATCCACTG CTCTGCGCAG GCTGGCTCCT
CCCACGAGCT GTTGTCCATC GGCTCAAGAT CAGCTGGCCT CTGCCTGGTT CCCTGCCTGG
ATCACCCTCC TCCCAGCGCA CCCATGGGAA ACACAGCCTG TCCCAGGTCT TCCCATCCAT
CAAACTTGCA TCCCTGTGCT ATGCATCCTT CCACCTCCAC ACCCCAAATG GGGCAGCATC
TGTGCTACTT CAACATAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.