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VAMP3 cDNA ORF clone, Homo sapiens (human)

Gene Symbol VAMP3
Entrez Gene ID 9341
Full Name vesicle-associated membrane protein 3
Synonyms CEB
General protein information
Preferred Names
vesicle-associated membrane protein 3
Names
vesicle-associated membrane protein 3
VAMP-3
cellubrevin
synaptobrevin-3
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

1

1p36.23

Summary Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. This gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Because of its high homology to other known VAMPs, its broad tissue distribution, and its subcellular localization, the protein encoded by this gene was shown to be the human equivalent of the rodent cellubrevin. In platelets the protein resides on a compartment that is not mobilized to the plasma membrane on calcium or thrombin stimulation. [provided by RefSeq, Jul 2008]. lac of sum
Disorder MIM:

603657

Disorder Html:





The following VAMP3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the VAMP3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu15733 NM_004781 Homo sapiens vesicle-associated membrane protein 3 (VAMP3), mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$69.30
$99.00

*Business Day
**You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.


CloneID OHu15733
Accession Version NM_004781.3 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 303bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product vesicle-associated membrane protein 3
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC005941.1 and BC003570.1. On Feb 13, 2004 this sequence version replaced gi:9257252. Summary: Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. This gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Because of its high homology to other known VAMPs, its broad tissue distribution, and its subcellular localization, the protein encoded by this gene was shown to be the human equivalent of the rodent cellubrevin. In platelets the protein resides on a compartment that is not mobilized to the plasma membrane on calcium or thrombin stimulation. [provided by RefSeq, Jul 2008]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC003570.1, BC007050.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
ATGTCTACAG GTCCAACTGC TGCCACTGGC AGTAATCGAA GACTTCAGCA GACACAAAAT 
CAAGTAGATG AGGTGGTGGA CATAATGCGA GTTAACGTGG ACAAGGTTCT GGAAAGAGAC
CAGAAGCTCT CTGAGTTAGA CGACCGTGCA GACGCACTGC AGGCAGGCGC TTCTCAATTT
GAAACGAGCG CAGCCAAGTT GAAGAGGAAA TATTGGTGGA AGAATTGCAA GATGTGGGCA
ATCGGGATTA CTGTTCTGGT TATCTTCATC ATCATCATCA TCGTGTGGGT TGTCTCTTCA
TGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeqNP_004772.1
CDS116..418
Misc Feature(1)74..76(+)
Misc Feature(2)119..121(+)
Misc Feature(3)146..>358(+)
Misc Feature(4)152..340(+)
Misc Feature(5)155..340(+)
Misc Feature(6)230..232(+)
Misc Feature(7)347..409(+)
Exon (1)1..117
Gene:VAMP3
Gene Synonym:
Exon (2)118..187
Gene:VAMP3
Gene Synonym:
Exon (3)188..346
Gene:VAMP3
Gene Synonym:
Exon (4)347..398
Gene:VAMP3
Gene Synonym:
Exon (5)399..2205
Gene:VAMP3
Gene Synonym:
Translation
Position Chain Variation Link
14 14 a, c dbSNP:536160753
21 21 c, t dbSNP:376930466
24 24 a, c, t dbSNP:72853889
42 42 c, t dbSNP:536689757
65 65 c, t dbSNP:772114634
67 67 c, t dbSNP:371387536
68 68 c, t dbSNP:760597584
69 69 c, t dbSNP:770111635
70 70 c, t dbSNP:373739555
73 73 c, t dbSNP:763280032
76 76 a, g dbSNP:764013502
79 79 -, ct dbSNP:746802918
80 80 c, t dbSNP:375639351
81 81 c, t dbSNP:762210082
83 83 c, t dbSNP:768115099
84 84 -, tcg dbSNP:770671231
85 85 c, t dbSNP:576867392
86 86 c, g dbSNP:756427638
91 91 c, t dbSNP:780421766
92 92 a, g dbSNP:753433372
97 97 c, t dbSNP:754666562
101 101 a, g, t dbSNP:541088448
106 106 a, c dbSNP:758247633
110 110 a, g dbSNP:777808323
117 117 c, t dbSNP:746963670
122 122 a, g dbSNP:757330685
123 123 c, t dbSNP:781121112
124 124 a, g, t dbSNP:745721225
127 127 c, t dbSNP:774590605
130 130 a, g dbSNP:748338371
140 140 a, c dbSNP:772136702
142 142 g, t dbSNP:773286763
146 146 a, g dbSNP:540062245
152 152 c, t dbSNP:549256170
156 156 a, g dbSNP:766930306
169 169 a, g dbSNP:558063108
174 174 a, g dbSNP:759987707
178 178 a, g dbSNP:765553952
182 182 a, g dbSNP:752334689
190 190 -, g dbSNP:775094523
190 190 g, t dbSNP:114491660
193 193 a, g dbSNP:190930592
211 211 c, t dbSNP:762652944
212 212 a, g dbSNP:763888128
213 213 c, t dbSNP:138476443
219 219 a, g dbSNP:761362677
221 221 c, g dbSNP:767155660
227 227 a, g dbSNP:750314246
242 242 -, ctct dbSNP:762427378
254 254 a, c, g dbSNP:756011875
256 256 c, t dbSNP:199685566
258 258 a, g dbSNP:758601418
260 260 c, t dbSNP:778011351
264 264 c, t dbSNP:747264524
268 268 c, t dbSNP:770952194
278 278 g, t dbSNP:781134285
283 283 c, t dbSNP:746381296
284 284 a, g dbSNP:770261916
285 285 c, t dbSNP:541622542
286 286 g, t dbSNP:560129906
300 300 c, t dbSNP:145085517
301 301 a, c, g dbSNP:114336504
304 304 c, t dbSNP:141188464
305 305 a, g dbSNP:749971635
314 314 a, t dbSNP:760652046
339 339 -, t dbSNP:768074089
339 339 a, t dbSNP:766280350
343 343 a, g dbSNP:17856157
346 346 a, g dbSNP:753637786
348 348 c, t dbSNP:553625650
350 350 c, t dbSNP:765945268
353 353 a, g dbSNP:374984144
356 356 a, g dbSNP:747982809
358 358 c, t dbSNP:149457052
361 361 g, t dbSNP:752545513
365 365 a, g dbSNP:116416205
367 367 a, t dbSNP:57351330
368 368 a, g dbSNP:767672011
370 370 c, t dbSNP:750684812
372 372 c, t dbSNP:756094232
373 373 a, g dbSNP:780192464
380 380 -, tca, tcatca dbSNP:755176457
381 381 -, tcatca dbSNP:758396306
381 381 -, tca dbSNP:752706951
387 387 c, t dbSNP:749743327
397 397 c, t dbSNP:140568149
398 398 a, c, g dbSNP:369968090
407 407 a, g dbSNP:770673246
411 411 a, c dbSNP:144427684
414 414 a, c, t dbSNP:374611913
423 423 a, c dbSNP:199871347
428 428 a, g dbSNP:775353122
437 437 a, g dbSNP:762957738
439 439 c, t dbSNP:768265177
441 441 g, t dbSNP:200029799
447 447 c, g dbSNP:368251108
448 448 a, c dbSNP:766760090
452 452 a, c dbSNP:753941292
456 456 a, t dbSNP:759652735
457 457 c, t dbSNP:561087372
465 465 c, g dbSNP:765430811
470 470 a, g dbSNP:768115846
476 476 c, g dbSNP:148779340
488 488 c, t dbSNP:1804680
491 491 c, t dbSNP:115611376
495 495 c, g dbSNP:200346978
510 510 c, t dbSNP:560925997
516 516 a, t dbSNP:529009417
527 527 c, g dbSNP:181353020
558 558 a, g dbSNP:562590445
577 577 c, t dbSNP:533402224
578 578 a, g dbSNP:762275467
580 580 a, c dbSNP:774727571
589 589 c, t dbSNP:551557461
590 590 -, aga dbSNP:760544505
591 591 c, g dbSNP:759409433
604 604 a, g dbSNP:566827706
606 606 a, c dbSNP:534182855
607 607 c, t dbSNP:112086928
632 632 a, g dbSNP:773593767
657 657 a, c dbSNP:697678
739 739 c, t dbSNP:142391561
756 756 c, g dbSNP:759864189
761 761 -, c dbSNP:552674247
795 795 a, g dbSNP:532323545
828 828 a, g dbSNP:763093107
851 851 c, g dbSNP:184288726
883 883 c, t dbSNP:766605151
953 953 a, c dbSNP:556421707
988 988 -, ttg dbSNP:767558108
988 988 c, t dbSNP:751789764
1016 1016 a, g dbSNP:759661312
1022 1022 -, tt dbSNP:756949265
1022 1022 a, g dbSNP:146891009
1023 1023 -, tt dbSNP:574411485
1055 1055 a, t dbSNP:139737794
1096 1096 a, c dbSNP:143990798
1109 1109 c, t dbSNP:573187619
1132 1132 c, t dbSNP:41307000
1186 1186 c, t dbSNP:78902591
1231 1231 g, t dbSNP:757282353
1234 1234 g, t dbSNP:78955069
1300 1300 a, g dbSNP:544187532
1311 1311 a, g dbSNP:562492358
1312 1312 c, t dbSNP:114023518
1321 1321 a, g dbSNP:778813460
1330 1330 c, t dbSNP:545207608
1331 1331 a, g dbSNP:560279323
1338 1338 a, t dbSNP:527857752
1387 1387 a, g dbSNP:549300047
1407 1407 a, g dbSNP:540470285
1411 1411 a, g dbSNP:35024711
1422 1422 c, g dbSNP:531654007
1437 1437 a, g dbSNP:550099370
1464 1464 c, g dbSNP:112537943
1482 1482 a, g dbSNP:66781032
1519 1519 c, t dbSNP:539097478
1634 1634 a, g dbSNP:113567174
1639 1639 c, g dbSNP:697679
1641 1641 a, g dbSNP:566703647
1673 1673 a, t dbSNP:371280303
1703 1703 a, g dbSNP:764885331
1710 1710 c, t dbSNP:555417161
1753 1753 a, c dbSNP:181057810
1779 1779 c, g dbSNP:746680752
1802 1802 a, g dbSNP:187177904
1826 1826 a, g dbSNP:768189024
1862 1862 c, t dbSNP:556085307
1864 1864 c, t dbSNP:191994422
1907 1907 g, t dbSNP:181652596
1936 1936 a, g dbSNP:780586207
2003 2003 c, g, t dbSNP:1048773
2042 2042 c, t dbSNP:755389564
2043 2043 a, g dbSNP:1048785
2045 2045 g, t dbSNP:773503968
2110 2110 c, t dbSNP:542808958
2116 2116 c, g dbSNP:771269703
2124 2124 c, t dbSNP:186852082
2126 2126 -, t dbSNP:34886825
2135 2135 c, t dbSNP:150123963
2170 2170 a, c dbSNP:1048806
2175 2175 a, t dbSNP:570243843

Target ORF information:

RefSeq Version NM_004781
Organism Homo sapiens (human)
Definition Homo sapiens vesicle-associated membrane protein 3 (VAMP3), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_004781

ORF Insert Sequence:

1
61
121
181
241
301
ATGTCTACAG GTCCAACTGC TGCCACTGGC AGTAATCGAA GACTTCAGCA GACACAAAAT 
CAAGTAGATG AGGTGGTGGA CATAATGCGA GTTAACGTGG ACAAGGTTCT GGAAAGAGAC
CAGAAGCTCT CTGAGTTAGA CGACCGTGCA GACGCACTGC AGGCAGGCGC TTCTCAATTT
GAAACGAGCG CAGCCAAGTT GAAGAGGAAA TATTGGTGGA AGAATTGCAA GATGTGGGCA
ATCGGGATTA CTGTTCTGGT TATCTTCATC ATCATCATCA TCGTGTGGGT TGTCTCTTCA
TGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

 
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