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CCL4L2 cDNA ORF clone, Homo sapiens (human)

Gene Symbol CCL4L2
Entrez Gene ID 9560
Full Name chemokine (C-C motif) ligand 4-like 2
Synonyms AT744.2, CCL4L, SCYA4L, SCYQ4L2
General protein information
Preferred Names
C-C motif chemokine 4-like
Names
C-C motif chemokine 4-like
MIP-1-beta
macrophage inflammatory protein-1b2
lymphocyte activation gene 1 protein
macrophage inflammatory protein 1-beta
monocyte adherence-induced protein 5-alpha
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

17

17q12

Summary This gene is one of several cytokine genes that are clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins that function in inflammatory and immunoregulatory processes. The protein encoded by this family member is similar to the chemokine (C-C motif) ligand 4 product, which inhibits HIV entry by binding to the cellular receptor CCR5. The copy number of this gene varies among individuals, where most individuals have one to five copies. This gene copy contains a non-consensus splice acceptor site at the 3' terminal exon found in other highly similar gene copies, and it thus uses other alternative splice sites for the 3' terminal exon, resulting in multiple transcript variants. [provided by RefSeq, Apr 2014]. lac of sum
Disorder MIM:

610757


mRNA and Protein(s)

mRNA Protein Name
NM_001291473 NP_001278402 C-C motif chemokine 4-like isoform 5 precursor
NM_001291471 NP_001278400 C-C motif chemokine 4-like isoform 3 precursor
NM_001291474 NP_001278403 C-C motif chemokine 4-like isoform 6 precursor
NM_001291468 NP_001278397 C-C motif chemokine 4-like isoform 1 precursor
NM_001291469 NP_001278398 C-C motif chemokine 4-like isoform 2 precursor
NM_001291470 NP_001278399 C-C motif chemokine 4-like isoform 2 precursor
NM_001291472 NP_001278401 C-C motif chemokine 4-like isoform 4 precursor
NM_001291475 NP_001278404 C-C motif chemokine 4-like isoform 7 precursor



GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following CCL4L2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CCL4L2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu16103 NM_001291473 Homo sapiens chemokine (C-C motif) ligand 4-like 2 (CCL4L2), transcript variant CCL4L2e, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $69.30
$99.00
OHu16101 NM_001291471 Homo sapiens chemokine (C-C motif) ligand 4-like 2 (CCL4L2), transcript variant CCL4L2c, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $69.30
$99.00
OHu16104 NM_001291474 Homo sapiens chemokine (C-C motif) ligand 4-like 2 (CCL4L2), transcript variant CCL4L2bdelta2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $69.30
$99.00
OHu16068 NM_001291468 Homo sapiens chemokine (C-C motif) ligand 4-like 2 (CCL4L2), transcript variant CCL4L2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $69.30
$99.00
OHu16099 NM_001291469 Homo sapiens chemokine (C-C motif) ligand 4-like 2 (CCL4L2), transcript variant CCL4L2b1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $69.30
$99.00
OHu16100 NM_001291470 Homo sapiens chemokine (C-C motif) ligand 4-like 2 (CCL4L2), transcript variant CCL4L2b2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $69.30
$99.00
OHu16102 NM_001291472 Homo sapiens chemokine (C-C motif) ligand 4-like 2 (CCL4L2), transcript variant CCL4L2d, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $69.30
$99.00
OHu16105 NM_001291475 Homo sapiens chemokine (C-C motif) ligand 4-like 2 (CCL4L2), transcript variant CCL4L2f, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $69.30
$99.00
Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone 30% OFF
2-4 Clone 40% OFF
5 or more Clone 50% OFF
All Other ORF Clones
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*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu16103
Clone ID Related Accession (Same CDS sequence) NM_001291473
Accession Version NM_001291473.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 261bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 13-MAY-2015
Organism Homo sapiens (human)
Product C-C motif chemokine 4-like isoform 5 precursor
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AY766455.1. Transcript Variant: This variant (CCL4L2e) uses an alternate splice site in the 3' terminal exon, and it thus differs in the 3' coding region and 3' UTR, compared to variant CCL4L2. The encoded isoform (5) has a distinct C-terminus and is shorter than isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY766455.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
ATGAAGCTCT GCGTGACTGT CCTGTCTCTC CTCGTGCTAG TAGCTGCCTT CTGCTCTCTA 
GCACTCTCAG CACCAATGGG CTCAGACCCT CCCACCGCCT GCTGCTTTTC TTACACCGCG
AGGAAGCTTC CTCGCAACTT TGTGGTAGAT TACTATGAGA CCAGCAGCCT CTGCTCCCAG
CCAGCTGTGG TAGCTGCCCC ACATGGACCA TGGTCAGGCA GAGGAAGATG CCTACCACAG
GCAAGGGATA AAGCCAGATG A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001278402.1
CDS80..340
Misc Feature(1)53..55(+)
Misc Feature(2)170..>274(+)
Misc Feature(3)179..223(+)
Misc Feature(4)185..220(+)
Misc Feature(5)212..220(+)
Misc Feature(6)239..259(+)
Exon (1)1..155
Gene:CCL4L2
Gene Synonym:
Exon (2)156..270
Gene:CCL4L2
Gene Synonym:
Exon (3)271..785
Gene:CCL4L2
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_001291473
Organism Homo sapiens (human)
Definition Homo sapiens chemokine (C-C motif) ligand 4-like 2 (CCL4L2), transcript variant CCL4L2e, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001291473

ORF Insert Sequence:

1
61
121
181
241
ATGAAGCTCT GCGTGACTGT CCTGTCTCTC CTCGTGCTAG TAGCTGCCTT CTGCTCTCTA 
GCACTCTCAG CACCAATGGG CTCAGACCCT CCCACCGCCT GCTGCTTTTC TTACACCGCG
AGGAAGCTTC CTCGCAACTT TGTGGTAGAT TACTATGAGA CCAGCAGCCT CTGCTCCCAG
CCAGCTGTGG TAGCTGCCCC ACATGGACCA TGGTCAGGCA GAGGAAGATG CCTACCACAG
GCAAGGGATA AAGCCAGATG A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu16101
Clone ID Related Accession (Same CDS sequence) NM_001291471
Accession Version NM_001291471.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 312bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 13-MAY-2015
Organism Homo sapiens (human)
Product C-C motif chemokine 4-like isoform 3 precursor
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AY766453.1. Transcript Variant: This variant (CCL4L2c) uses an alternate splice site in the 3' terminal exon, and it thus differs in the 3' coding region and 3' UTR, compared to variant CCL4L2. The encoded isoform (3) has a distinct C-terminus and is longer than isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY766453.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
ATGAAGCTCT GCGTGACTGT CCTGTCTCTC CTCGTGCTAG TAGCTGCCTT CTGCTCTCTA 
GCACTCTCAG CACCAATGGG CTCAGACCCT CCCACCGCCT GCTGCTTTTC TTACACCGCG
AGGAAGCTTC CTCGCAACTT TGTGGTAGAT TACTATGAGA CCAGCAGCCT CTGCTCCCAG
CCAGCTGTGG TTTACAGGGA GTCTGCTTCC AGTGCTGCTC CGGGAAGGAT CCCATCCACC
AGAGCTGCCC CACATGGACC ATGGTCAGGC AGAGGAAGAT GCCTACCACA GGCAAGGGAT
AAAGCCAGAT GA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001278400.1
CDS80..391
Misc Feature(1)53..55(+)
Misc Feature(2)170..>271(+)
Misc Feature(3)179..223(+)
Misc Feature(4)185..220(+)
Misc Feature(5)212..220(+)
Misc Feature(6)239..259(+)
Exon (1)1..155
Gene:CCL4L2
Gene Synonym:
Exon (2)156..270
Gene:CCL4L2
Gene Synonym:
Exon (3)271..836
Gene:CCL4L2
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_001291471
Organism Homo sapiens (human)
Definition Homo sapiens chemokine (C-C motif) ligand 4-like 2 (CCL4L2), transcript variant CCL4L2c, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001291471

ORF Insert Sequence:

1
61
121
181
241
301
ATGAAGCTCT GCGTGACTGT CCTGTCTCTC CTCGTGCTAG TAGCTGCCTT CTGCTCTCTA 
GCACTCTCAG CACCAATGGG CTCAGACCCT CCCACCGCCT GCTGCTTTTC TTACACCGCG
AGGAAGCTTC CTCGCAACTT TGTGGTAGAT TACTATGAGA CCAGCAGCCT CTGCTCCCAG
CCAGCTGTGG TTTACAGGGA GTCTGCTTCC AGTGCTGCTC CGGGAAGGAT CCCATCCACC
AGAGCTGCCC CACATGGACC ATGGTCAGGC AGAGGAAGAT GCCTACCACA GGCAAGGGAT
AAAGCCAGAT GA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu16104
Clone ID Related Accession (Same CDS sequence) NM_001291474
Accession Version NM_001291474.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 207bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 13-MAY-2015
Organism Homo sapiens (human)
Product C-C motif chemokine 4-like isoform 6 precursor
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AY766457.1. Transcript Variant: This variant (CCL4L2bdelta2) lacks an alternate internal exon and uses an alternate splice site in the 3' terminal exon, and it thus differs in the 3' coding region and 3' UTR, compared to variant CCL4L2. The encoded isoform (6) has a distinct C-terminus and is shorter than isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY766457.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2159764, SAMEA2162895 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
ATGAAGCTCT GCGTGACTGT CCTGTCTCTC CTCGTGCTAG TAGCTGCCTT CTGCTCTCTA 
GCACTCTCAG CACCAACTAA ATCCAGTGAG TGGAAGTTAC AGGGAGTCTG CTTCCAGTGC
TGCTCCGGGA AGGATCCCAT CCACCAGAGC TGCCCCACAT GGACCATGGT CAGGCAGAGG
AAGATGCCTA CCACAGGCAA GGGATAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001278403.1
CDS80..286
Misc Feature(1)53..55(+)
Exon (1)1..155
Gene:CCL4L2
Gene Synonym:
Exon (2)156..741
Gene:CCL4L2
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_001291474
Organism Homo sapiens (human)
Definition Homo sapiens chemokine (C-C motif) ligand 4-like 2 (CCL4L2), transcript variant CCL4L2bdelta2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001291474

ORF Insert Sequence:

1
61
121
181
ATGAAGCTCT GCGTGACTGT CCTGTCTCTC CTCGTGCTAG TAGCTGCCTT CTGCTCTCTA 
GCACTCTCAG CACCAACTAA ATCCAGTGAG TGGAAGTTAC AGGGAGTCTG CTTCCAGTGC
TGCTCCGGGA AGGATCCCAT CCACCAGAGC TGCCCCACAT GGACCATGGT CAGGCAGAGG
AAGATGCCTA CCACAGGCAA GGGATAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu16068
Clone ID Related Accession (Same CDS sequence) NM_001291468
Accession Version NM_001291468.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 264bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 13-MAY-2015
Organism Homo sapiens (human)
Product C-C motif chemokine 4-like isoform 1 precursor
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AY766450.1. Transcript Variant: This variant (CCL4L2) encodes isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY766450.1, CD559275.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA2142348 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
ATGAAGCTCT GCGTGACTGT CCTGTCTCTC CTCGTGCTAG TAGCTGCCTT CTGCTCTCTA 
GCACTCTCAG CACCAATGGG CTCAGACCCT CCCACCGCCT GCTGCTTTTC TTACACCGCG
AGGAAGCTTC CTCGCAACTT TGTGGTAGAT TACTATGAGA CCAGCAGCCT CTGCTCCCAG
CCAGCTGTGG TAGGCAAGCA AGTCTGCGCT GACCCCAGTG AGTCCTGGGT CCAGGAGTAC
GTGTATGACC TGGAACTGAA CTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001278397.1
CDS80..343
Misc Feature(1)53..55(+)
Misc Feature(2)179..334(+)
Misc Feature(3)179..334(+)
Misc Feature(4)185..334(+)
Misc Feature(5)185..286(+)
Misc Feature(6)185..283(+)
Misc Feature(7)185..220(+)
Misc Feature(8)191..334(+)
Misc Feature(9)197..277(+)
Misc Feature(10)236..325(+)
Misc Feature(11)248..253(+)
Exon (1)1..155
Gene:CCL4L2
Gene Synonym:
Exon (2)156..270
Gene:CCL4L2
Gene Synonym:
Exon (3)271..652
Gene:CCL4L2
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_001291468
Organism Homo sapiens (human)
Definition Homo sapiens chemokine (C-C motif) ligand 4-like 2 (CCL4L2), transcript variant CCL4L2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001291468

ORF Insert Sequence:

1
61
121
181
241
ATGAAGCTCT GCGTGACTGT CCTGTCTCTC CTCGTGCTAG TAGCTGCCTT CTGCTCTCTA 
GCACTCTCAG CACCAATGGG CTCAGACCCT CCCACCGCCT GCTGCTTTTC TTACACCGCG
AGGAAGCTTC CTCGCAACTT TGTGGTAGAT TACTATGAGA CCAGCAGCCT CTGCTCCCAG
CCAGCTGTGG TAGGCAAGCA AGTCTGCGCT GACCCCAGTG AGTCCTGGGT CCAGGAGTAC
GTGTATGACC TGGAACTGAA CTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu16099
Clone ID Related Accession (Same CDS sequence) NM_001291469
Accession Version NM_001291469.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 195bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 13-MAY-2015
Organism Homo sapiens (human)
Product C-C motif chemokine 4-like isoform 2 precursor
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AY766451.1. Transcript Variant: This variant (CCL4L2b1) uses an alternate splice site in the 3' terminal exon, and it thus contains an early termination codon and differs in its 3' UTR, compared to variant CCL4L2. The encoded isoform (2) is shorter at the C-terminus, compared to isoform 1. Both variants CCL4L2b1 and CCL4L2b2 encode isoform 2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY766451.1, BC092445.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
ATGAAGCTCT GCGTGACTGT CCTGTCTCTC CTCGTGCTAG TAGCTGCCTT CTGCTCTCTA 
GCACTCTCAG CACCAATGGG CTCAGACCCT CCCACCGCCT GCTGCTTTTC TTACACCGCG
AGGAAGCTTC CTCGCAACTT TGTGGTAGAT TACTATGAGA CCAGCAGCCT CTGCTCCCAG
CCAGCTGTGG TCTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001278398.1
CDS80..274
Misc Feature(1)53..55(+)
Misc Feature(2)170..>271(+)
Misc Feature(3)179..223(+)
Misc Feature(4)185..220(+)
Misc Feature(5)212..220(+)
Misc Feature(6)239..259(+)
Exon (1)1..155
Gene:CCL4L2
Gene Synonym:
Exon (2)156..270
Gene:CCL4L2
Gene Synonym:
Exon (3)271..856
Gene:CCL4L2
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_001291469
Organism Homo sapiens (human)
Definition Homo sapiens chemokine (C-C motif) ligand 4-like 2 (CCL4L2), transcript variant CCL4L2b1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001291469

ORF Insert Sequence:

1
61
121
181
ATGAAGCTCT GCGTGACTGT CCTGTCTCTC CTCGTGCTAG TAGCTGCCTT CTGCTCTCTA 
GCACTCTCAG CACCAATGGG CTCAGACCCT CCCACCGCCT GCTGCTTTTC TTACACCGCG
AGGAAGCTTC CTCGCAACTT TGTGGTAGAT TACTATGAGA CCAGCAGCCT CTGCTCCCAG
CCAGCTGTGG TCTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu16100
Clone ID Related Accession (Same CDS sequence) NM_001291470
Accession Version NM_001291470.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 195bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 13-MAY-2015
Organism Homo sapiens (human)
Product C-C motif chemokine 4-like isoform 2 precursor
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AY766452.1. Transcript Variant: This variant (CCL4L2b2) fails to splice out the 3'-most intron, and it thus contains an early termination codon and differs in its 3' UTR, compared to variant CCL4L2. The encoded isoform (2) is shorter at the C-terminus, compared to isoform 1. Both variants CCL4L2b1 and CCL4L2b2 encode isoform 2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY766452.1, CD559248.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
ATGAAGCTCT GCGTGACTGT CCTGTCTCTC CTCGTGCTAG TAGCTGCCTT CTGCTCTCTA 
GCACTCTCAG CACCAATGGG CTCAGACCCT CCCACCGCCT GCTGCTTTTC TTACACCGCG
AGGAAGCTTC CTCGCAACTT TGTGGTAGAT TACTATGAGA CCAGCAGCCT CTGCTCCCAG
CCAGCTGTGG TGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001278399.1
CDS80..274
Misc Feature(1)53..55(+)
Misc Feature(2)170..>271(+)
Misc Feature(3)179..223(+)
Misc Feature(4)185..220(+)
Misc Feature(5)212..220(+)
Misc Feature(6)239..259(+)
Exon (1)1..155
Gene:CCL4L2
Gene Synonym:
Exon (2)156..1258
Gene:CCL4L2
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_001291470
Organism Homo sapiens (human)
Definition Homo sapiens chemokine (C-C motif) ligand 4-like 2 (CCL4L2), transcript variant CCL4L2b2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001291470

ORF Insert Sequence:

1
61
121
181
ATGAAGCTCT GCGTGACTGT CCTGTCTCTC CTCGTGCTAG TAGCTGCCTT CTGCTCTCTA 
GCACTCTCAG CACCAATGGG CTCAGACCCT CCCACCGCCT GCTGCTTTTC TTACACCGCG
AGGAAGCTTC CTCGCAACTT TGTGGTAGAT TACTATGAGA CCAGCAGCCT CTGCTCCCAG
CCAGCTGTGG TGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu16102
Clone ID Related Accession (Same CDS sequence) NM_001291472
Accession Version NM_001291472.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 291bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 13-MAY-2015
Organism Homo sapiens (human)
Product C-C motif chemokine 4-like isoform 4 precursor
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AY766454.1. Transcript Variant: This variant (CCL4L2d) uses an alternate splice site in the 3' terminal exon, and it thus differs in the 3' coding region and 3' UTR, compared to variant CCL4L2. The encoded isoform (4) has a distinct C-terminus and is longer than isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY766454.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
ATGAAGCTCT GCGTGACTGT CCTGTCTCTC CTCGTGCTAG TAGCTGCCTT CTGCTCTCTA 
GCACTCTCAG CACCAATGGG CTCAGACCCT CCCACCGCCT GCTGCTTTTC TTACACCGCG
AGGAAGCTTC CTCGCAACTT TGTGGTAGAT TACTATGAGA CCAGCAGCCT CTGCTCCCAG
CCAGCTGTGG TTGCTGCTCC GGGAAGGATC CCATCCACCA GAGCTGCCCC ACATGGACCA
TGGTCAGGCA GAGGAAGATG CCTACCACAG GCAAGGGATA AAGCCAGATG A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001278401.1
CDS80..370
Misc Feature(1)53..55(+)
Misc Feature(2)170..322(+)
Misc Feature(3)179..223(+)
Misc Feature(4)185..220(+)
Misc Feature(5)212..220(+)
Misc Feature(6)239..259(+)
Exon (1)1..155
Gene:CCL4L2
Gene Synonym:
Exon (2)156..270
Gene:CCL4L2
Gene Synonym:
Exon (3)271..815
Gene:CCL4L2
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_001291472
Organism Homo sapiens (human)
Definition Homo sapiens chemokine (C-C motif) ligand 4-like 2 (CCL4L2), transcript variant CCL4L2d, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001291472

ORF Insert Sequence:

1
61
121
181
241
ATGAAGCTCT GCGTGACTGT CCTGTCTCTC CTCGTGCTAG TAGCTGCCTT CTGCTCTCTA 
GCACTCTCAG CACCAATGGG CTCAGACCCT CCCACCGCCT GCTGCTTTTC TTACACCGCG
AGGAAGCTTC CTCGCAACTT TGTGGTAGAT TACTATGAGA CCAGCAGCCT CTGCTCCCAG
CCAGCTGTGG TTGCTGCTCC GGGAAGGATC CCATCCACCA GAGCTGCCCC ACATGGACCA
TGGTCAGGCA GAGGAAGATG CCTACCACAG GCAAGGGATA AAGCCAGATG A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu16105
Clone ID Related Accession (Same CDS sequence) NM_001291475
Accession Version NM_001291475.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 312bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 13-MAY-2015
Organism Homo sapiens (human)
Product C-C motif chemokine 4-like isoform 7 precursor
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AY766458.1. Transcript Variant: This variant (CCL4L2f) uses an alternate splice site in the 3' terminal exon, and it thus differs in the 3' coding region and 3' UTR, compared to variant CCL4L2. The encoded isoform (7) has a distinct C-terminus and is longer than isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY766458.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
ATGAAGCTCT GCGTGACTGT CCTGTCTCTC CTCGTGCTAG TAGCTGCCTT CTGCTCTCTA 
GCACTCTCAG CACCAATGGG CTCAGACCCT CCCACCGCCT GCTGCTTTTC TTACACCGCG
AGGAAGCTTC CTCGCAACTT TGTGGTAGAT TACTATGAGA CCAGCAGCCT CTGCTCCCAG
CCAGCTGTGG TTGAGTGGAA GTTACAGGGA GTCTGCTTCC AGTGCTGCTC CGGGAAGGAT
CCCATCCACC AGAGCTGCCC CACATGGACC ATGGTCAGGC AGAGGAAGAT GCCTACCACA
GGCAAGGGAT AA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001278404.1
CDS80..391
Misc Feature(1)53..55(+)
Misc Feature(2)170..>295(+)
Misc Feature(3)179..223(+)
Misc Feature(4)185..220(+)
Misc Feature(5)212..220(+)
Misc Feature(6)239..259(+)
Exon (1)1..155
Gene:CCL4L2
Gene Synonym:
Exon (2)156..270
Gene:CCL4L2
Gene Synonym:
Exon (3)271..846
Gene:CCL4L2
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_001291475
Organism Homo sapiens (human)
Definition Homo sapiens chemokine (C-C motif) ligand 4-like 2 (CCL4L2), transcript variant CCL4L2f, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001291475

ORF Insert Sequence:

1
61
121
181
241
301
ATGAAGCTCT GCGTGACTGT CCTGTCTCTC CTCGTGCTAG TAGCTGCCTT CTGCTCTCTA 
GCACTCTCAG CACCAATGGG CTCAGACCCT CCCACCGCCT GCTGCTTTTC TTACACCGCG
AGGAAGCTTC CTCGCAACTT TGTGGTAGAT TACTATGAGA CCAGCAGCCT CTGCTCCCAG
CCAGCTGTGG TTGAGTGGAA GTTACAGGGA GTCTGCTTCC AGTGCTGCTC CGGGAAGGAT
CCCATCCACC AGAGCTGCCC CACATGGACC ATGGTCAGGC AGAGGAAGAT GCCTACCACA
GGCAAGGGAT AA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

book

Comparison of a quantitative Real-Time PCR assay and droplet digital PCR for copy number analysis of the CCL4L genes
Infect. Genet. Evol. 25, 28-35 (2014)
Bharuthram A, Paximadis M, Picton AC and Tiemessen CT.


book

CCL4L polymorphisms and CCL4/CCL4L serum levels are associated with psoriasis severity
J. Invest. Dermatol. 131 (9), 1830-1837 (2011)
Pedrosa E, Carretero-Iglesia L, Boada A, Colobran R, Faner R, Pujol-Autonell I, Palou E, Esteve A, Pujol-Borrell R, Ferrandiz C, Juan M and Carrascosa JM.


book

Copy number variation in chemokine superfamily: the complex scene of CCL3L-CCL4L genes in health and disease
Clin. Exp. Immunol. 162 (1), 41-52 (2010)
Colobran R, Pedrosa E, Carretero-Iglesia L and Juan M.


book

Chemokine expression patterns in the systemic and genital tract compartments are associated with HIV-1 infection in women from Benin
J. Clin. Immunol. 30 (1), 90-98 (2010)
Lajoie J, Poudrier J, Massinga Loembe M, Guedou F, Leblond F, Labbe AC, Alary M and Roger M.


book

Combinatorial content of CCL3L and CCL4L gene copy numbers influence HIV-AIDS susceptibility in Ukrainian children
AIDS 23 (6), 679-688 (2009)
Shostakovich-Koretskaya L, Catano G, Chykarenko ZA, He W, Gornalusse G, Mummidi S, Sanchez R, Dolan MJ, Ahuja SS, Clark RA, Kulkarni H and Ahuja SK.


book

Multiple products derived from two CCL4 loci: high incidence of a new polymorphism in HIV+ patients
J. Immunol. 174 (9), 5655-5664 (2005)
Colobran R, Adreani P, Ashhab Y, Llano A, Este JA, Dominguez O, Pujol-Borrell R and Juan M.


book

The gene encoding the Act-2 cytokine. Genomic structure, HTLV-I/Tax responsiveness of 5' upstream sequences, and chromosomal localization
J. Biol. Chem. 266 (26), 17531-17536 (1991)
Napolitano M, Modi WS, Cevario SJ, Gnarra JR, Seuanez HN and Leonard WJ.


book

Two inflammatory mediator cytokine genes are closely linked and variably amplified on chromosome 17q
Nucleic Acids Res. 18 (11), 3261-3270 (1990)
Irving SG, Zipfel PF, Balke J, McBride OW, Morton CC, Burd PR, Siebenlist U and Kelly K.


book

A family of small inducible proteins secreted by leukocytes are members of a new superfamily that includes leukocyte and fibroblast-derived inflammatory agents, growth factors, and indicators of various activation processes
J. Immunol. 142 (2), 679-687 (1989)
Brown KD, Zurawski SM, Mosmann TR and Zurawski G.


book

Identification, cloning, and characterization of an immune activation gene
Proc. Natl. Acad. Sci. U.S.A. 85 (24), 9704-9708 (1988)
Lipes MA, Napolitano M, Jeang KT, Chang NT and Leonard WJ.


 
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