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GDF3 cDNA ORF clone, Homo sapiens (human)

Gene Symbol GDF3
Entrez Gene ID 9573
Full Name growth differentiation factor 3
Synonyms KFS3, MCOP7, MCOPCB6
General protein information
Preferred Names
growth/differentiation factor 3
Names
growth/differentiation factor 3
GDF-3
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

12

12p13.1

Summary The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. [provided by RefSeq, Jul 2008]. lac of sum
Disorder MIM:

606522

Disorder Html: Klippel-Feil syndrome 3, autosomal dominant, 613702 (3);





The following GDF3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the GDF3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu18012 NM_020634 Homo sapiens growth differentiation factor 3 (GDF3), mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$265.30
$379.00

*Business Day
**You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.


CloneID OHu18012
Accession Version NM_020634.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1095bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product growth/differentiation factor 3 precursor
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF263538.1. This sequence is a reference standard in the RefSeqGene project. Summary: The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. [provided by RefSeq, Jul 2008]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF263538.1, AY358875.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
ATGCTTCGTT TCTTGCCAGA TTTGGCTTTC AGCTTCCTGT TAATTCTGGC TTTGGGCCAG 
GCAGTCCAAT TTCAAGAATA TGTCTTTCTC CAATTTCTGG GCTTAGATAA GGCGCCTTCA
CCCCAGAAGT TCCAACCTGT GCCTTATATC TTGAAGAAAA TTTTCCAGGA TCGCGAGGCA
GCAGCGACCA CTGGGGTCTC CCGAGACTTA TGCTACGTAA AGGAGCTGGG CGTCCGCGGG
AATGTACTTC GCTTTCTCCC AGACCAAGGT TTCTTTCTTT ACCCAAAGAA AATTTCCCAA
GCTTCCTCCT GCCTGCAGAA GCTCCTCTAC TTTAACCTGT CTGCCATCAA AGAAAGGGAA
CAGTTGACAT TGGCCCAGCT GGGCCTGGAC TTGGGGCCCA ATTCTTACTA TAACCTGGGA
CCAGAGCTGG AACTGGCTCT GTTCCTGGTT CAGGAGCCTC ATGTGTGGGG CCAGACCACC
CCTAAGCCAG GTAAAATGTT TGTGTTGCGG TCAGTCCCAT GGCCACAAGG TGCTGTTCAC
TTCAACCTGC TGGATGTAGC TAAGGATTGG AATGACAACC CCCGGAAAAA TTTCGGGTTA
TTCCTGGAGA TACTGGTCAA AGAAGATAGA GACTCAGGGG TGAATTTTCA GCCTGAAGAC
ACCTGTGCCA GACTAAGATG CTCCCTTCAT GCTTCCCTGC TGGTGGTGAC TCTCAACCCT
GATCAGTGCC ACCCTTCTCG GAAAAGGAGA GCAGCCATCC CTGTCCCCAA GCTTTCTTGT
AAGAACCTCT GCCACCGTCA CCAGCTATTC ATTAACTTCC GGGACCTGGG TTGGCACAAG
TGGATCATTG CCCCCAAGGG GTTCATGGCA AATTACTGCC ATGGAGAGTG TCCCTTCTCA
CTGACCATCT CTCTCAACAG CTCCAATTAT GCTTTCATGC AAGCCCTGAT GCATGCCGTT
GACCCAGAGA TCCCCCAGGC TGTGTGTATC CCCACCAAGC TGTCTCCCAT TTCCATGCTC
TACCAGGACA ATAATGACAA TGTCATTCTA CGACATTATG AAGACATGGT AGTCGATGAA
TGTGGGTGTG GGTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeqNP_065685.1
CDS37..1131
Misc Feature(1)103..747(+)
Misc Feature(2)826..1128(+)
Exon (1)1..304
Gene:GDF3
Gene Synonym:
Exon (2)305..1224
Gene:GDF3
Gene Synonym:
Translation
Position Chain Variation Link
1 1 a, g dbSNP:753133941
5 5 c, g dbSNP:767808565
11 11 c, g dbSNP:747977252
12 12 c, t dbSNP:774336055
13 13 c, g dbSNP:201794479
15 15 g, t dbSNP:761412168
17 17 c, t dbSNP:201617669
19 19 a, c dbSNP:202105265
28 28 a, c dbSNP:749302382
30 30 a, g dbSNP:768378840
44 44 a, g dbSNP:760348396
51 51 g, t dbSNP:775326966
52 52 a, c dbSNP:771904963
53 53 c, t dbSNP:745795680
60 60 c, g dbSNP:778891651
73 73 c, t dbSNP:772608870
82 82 c, t dbSNP:375965543
84 84 a, g dbSNP:749403801
89 89 c, t dbSNP:777814239
93 93 c, t dbSNP:144267553
96 96 a, g dbSNP:752908581
103 103 a, c dbSNP:755588787
115 115 c, t dbSNP:372677651
119 119 c, t dbSNP:752043502
131 131 a, t dbSNP:767006467
139 139 c, t dbSNP:756777733
141 141 a, g dbSNP:753420067
142 142 a, g dbSNP:745461299
143 143 a, g dbSNP:760355594
147 147 a, g dbSNP:376751766
149 149 c, t dbSNP:767298278
150 150 a, g, t dbSNP:144330834
156 156 a, g dbSNP:770882875
159 159 c, g dbSNP:17727707
165 165 a, g dbSNP:773317311
185 185 c, t dbSNP:769819487
186 186 c, t dbSNP:748396785
188 188 c, t dbSNP:146378324
198 198 g, t dbSNP:375720989
208 208 c, t dbSNP:755337048
209 209 a, g dbSNP:747399055
210 210 c, t dbSNP:780667706
217 217 g, t dbSNP:142236459
221 221 c, g, t dbSNP:763647791
222 222 a, c, g dbSNP:752330502
230 230 c, g dbSNP:767175414
237 237 c, g dbSNP:368170617
238 238 c, g, t dbSNP:373943760
239 239 a, c, g dbSNP:372020374
241 241 a, g dbSNP:769843759
244 244 a, t dbSNP:748189142
245 245 a, t dbSNP:776944353
247 247 a, c, t dbSNP:747276140
251 251 a, g dbSNP:780544740
253 253 a, c, g dbSNP:746383540
257 257 a, g dbSNP:779295521
262 262 c, t dbSNP:755595648
268 268 a, c, g dbSNP:780787386
272 272 g, t dbSNP:376010944
277 277 a, g dbSNP:751268973
287 287 a, g dbSNP:766154682
300 300 a, c dbSNP:762659293
305 305 a, g dbSNP:753885780
306 306 c, t dbSNP:764266672
311 311 c, t dbSNP:760842902
324 324 a, g dbSNP:775800295
330 330 g, t dbSNP:772208133
336 336 a, g dbSNP:759910014
342 342 c, t dbSNP:574345420
353 353 a, c dbSNP:771380810
357 357 g, t dbSNP:769740914
358 358 c, t dbSNP:778254290
363 363 -, c dbSNP:763257668
365 365 a, t dbSNP:768095773
373 373 c, t dbSNP:148657137
374 374 c, t dbSNP:779716896
382 382 a, g dbSNP:150698698
383 383 c, t dbSNP:755559313
391 391 a, g dbSNP:781103234
392 392 g, t dbSNP:757186246
393 393 a, g dbSNP:753764679
394 394 a, g dbSNP:745444458
398 398 a, g dbSNP:766549202
400 400 c, t dbSNP:756217564
402 402 c, g dbSNP:752755070
406 406 a, t dbSNP:767679623
410 410 c, g, t dbSNP:774698812
415 415 c, g, t dbSNP:367760258
419 419 c, g dbSNP:763318155
431 431 a, g dbSNP:374666455
437 437 a, g dbSNP:773659015
454 454 a, g dbSNP:376200767
462 462 c, g dbSNP:748693630
470 470 c, t dbSNP:751673182
475 475 c, t dbSNP:771670847
484 484 a, g dbSNP:745503994
489 489 a, g dbSNP:370033213
490 490 a, g dbSNP:778633328
494 494 c, t dbSNP:375002535
499 499 a, g dbSNP:749120756
515 515 a, c dbSNP:199585440
516 516 c, t dbSNP:141133108
517 517 c, t dbSNP:148203165
524 524 c, t dbSNP:767485915
526 526 c, g dbSNP:553234393
534 534 a, g dbSNP:370123047
541 541 c, t dbSNP:755086344
543 543 a, g dbSNP:751671561
544 544 c, t dbSNP:752562423
545 545 a, c, g, t dbSNP:145849916
547 547 c, t dbSNP:762214167
570 570 c, t dbSNP:200893461
575 575 a, g dbSNP:771418785
576 576 c, g dbSNP:745398811
592 592 a, g dbSNP:773829666
596 596 c, t dbSNP:774332305
597 597 c, t dbSNP:748993038
603 603 c, t dbSNP:185665015
615 615 a, c, t dbSNP:144017935
619 619 c, t dbSNP:112895783
620 620 a, g dbSNP:146973734
630 630 c, t dbSNP:754962446
631 631 a, g dbSNP:778768975
632 632 g, t dbSNP:780146775
633 633 a, g dbSNP:758597222
639 639 c, t dbSNP:750702346
642 642 a, g dbSNP:374679722
646 646 a, t dbSNP:765581872
649 649 c, t dbSNP:762243949
652 652 c, g dbSNP:754242314
663 663 c, t dbSNP:764686808
665 665 a, g dbSNP:758931622
669 669 c, t dbSNP:773970500
671 671 c, t dbSNP:372790667
673 673 a, g dbSNP:12819884
676 676 a, g dbSNP:772999113
678 678 a, g, t dbSNP:149033500
682 682 a, t dbSNP:780949985
687 687 g, t dbSNP:768605823
697 697 a, c dbSNP:748834598
699 699 c, t dbSNP:145601141
717 717 c, t dbSNP:777121834
719 719 c, t dbSNP:780093783
720 720 c, g dbSNP:758541074
724 724 c, t dbSNP:750578270
725 725 a, g dbSNP:779122666
735 735 c, g dbSNP:757517038
748 748 c, g dbSNP:754263899
752 752 a, g dbSNP:764408748
754 754 a, c dbSNP:761226379
759 759 g, t dbSNP:753318345
775 775 c, t dbSNP:765916852
776 776 a, g dbSNP:150170520
785 785 a, g dbSNP:772947792
787 787 a, g dbSNP:764970795
796 796 a, c dbSNP:761410871
799 799 a, g dbSNP:776464295
805 805 a, g dbSNP:373667885
822 822 c, t dbSNP:746944156
828 828 c, t dbSNP:775410550
832 832 a, c, t dbSNP:140926412
833 833 a, g dbSNP:188391724
837 837 c, t dbSNP:375877721
838 838 c, t dbSNP:200736960
842 842 a, t dbSNP:755438714
854 854 c, t dbSNP:749525121
856 856 c, t dbSNP:387906946
866 866 a, g, t dbSNP:770848532
879 879 -, g dbSNP:773639222
881 881 a, t dbSNP:753193988
885 885 g, t dbSNP:768190600
889 889 c, g dbSNP:757954351
901 901 a, g dbSNP:749915057
909 909 c, t dbSNP:764677731
912 912 c, t dbSNP:146197089
918 918 c, t dbSNP:776153306
919 919 g, t dbSNP:763945162
922 922 c, g dbSNP:760520873
923 923 a, g dbSNP:775383579
926 926 g, t dbSNP:772035749
930 930 c, t dbSNP:745834613
946 946 c, t dbSNP:774437736
949 949 c, t dbSNP:770926140
950 950 c, t dbSNP:387906945
962 962 a, g dbSNP:777919038
966 966 c, t dbSNP:762094481
968 968 a, c dbSNP:369640821
976 976 a, c dbSNP:748566172
993 993 c, t dbSNP:781716089
994 994 a, g dbSNP:755496462
1010 1010 c, t dbSNP:566697767
1018 1018 c, g dbSNP:2302516
1020 1020 a, g dbSNP:778565308
1035 1035 a, g dbSNP:764004567
1056 1056 c, t dbSNP:377296873
1061 1061 -, a dbSNP:769932792
1073 1073 a, g dbSNP:753515885
1088 1088 a, g dbSNP:373439841
1099 1099 a, g dbSNP:760430648
1103 1103 c, t dbSNP:752447455
1110 1110 c, t dbSNP:753664039
1111 1111 a, g dbSNP:768472899
1119 1119 c, t dbSNP:774156825
1127 1127 c, g dbSNP:758777639
1128 1128 a, g dbSNP:750988910
1131 1131 a, g dbSNP:184349554
1133 1133 a, g dbSNP:762995770
1135 1135 g, t dbSNP:773456270
1156 1156 a, c dbSNP:770103702
1163 1163 c, t dbSNP:748406454
1167 1167 a, g dbSNP:368157243
1168 1168 g, t dbSNP:769148436
1170 1170 a, g dbSNP:372341342
1198 1198 c, t dbSNP:749962907
1220 1220 c, t dbSNP:776168538

Target ORF information:

RefSeq Version NM_020634
Organism Homo sapiens (human)
Definition Homo sapiens growth differentiation factor 3 (GDF3), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_020634

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
ATGCTTCGTT TCTTGCCAGA TTTGGCTTTC AGCTTCCTGT TAATTCTGGC TTTGGGCCAG 
GCAGTCCAAT TTCAAGAATA TGTCTTTCTC CAATTTCTGG GCTTAGATAA GGCGCCTTCA
CCCCAGAAGT TCCAACCTGT GCCTTATATC TTGAAGAAAA TTTTCCAGGA TCGCGAGGCA
GCAGCGACCA CTGGGGTCTC CCGAGACTTA TGCTACGTAA AGGAGCTGGG CGTCCGCGGG
AATGTACTTC GCTTTCTCCC AGACCAAGGT TTCTTTCTTT ACCCAAAGAA AATTTCCCAA
GCTTCCTCCT GCCTGCAGAA GCTCCTCTAC TTTAACCTGT CTGCCATCAA AGAAAGGGAA
CAGTTGACAT TGGCCCAGCT GGGCCTGGAC TTGGGGCCCA ATTCTTACTA TAACCTGGGA
CCAGAGCTGG AACTGGCTCT GTTCCTGGTT CAGGAGCCTC ATGTGTGGGG CCAGACCACC
CCTAAGCCAG GTAAAATGTT TGTGTTGCGG TCAGTCCCAT GGCCACAAGG TGCTGTTCAC
TTCAACCTGC TGGATGTAGC TAAGGATTGG AATGACAACC CCCGGAAAAA TTTCGGGTTA
TTCCTGGAGA TACTGGTCAA AGAAGATAGA GACTCAGGGG TGAATTTTCA GCCTGAAGAC
ACCTGTGCCA GACTAAGATG CTCCCTTCAT GCTTCCCTGC TGGTGGTGAC TCTCAACCCT
GATCAGTGCC ACCCTTCTCG GAAAAGGAGA GCAGCCATCC CTGTCCCCAA GCTTTCTTGT
AAGAACCTCT GCCACCGTCA CCAGCTATTC ATTAACTTCC GGGACCTGGG TTGGCACAAG
TGGATCATTG CCCCCAAGGG GTTCATGGCA AATTACTGCC ATGGAGAGTG TCCCTTCTCA
CTGACCATCT CTCTCAACAG CTCCAATTAT GCTTTCATGC AAGCCCTGAT GCATGCCGTT
GACCCAGAGA TCCCCCAGGC TGTGTGTATC CCCACCAAGC TGTCTCCCAT TTCCATGCTC
TACCAGGACA ATAATGACAA TGTCATTCTA CGACATTATG AAGACATGGT AGTCGATGAA
TGTGGGTGTG GGTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

 
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