||ORF Nucleotide Sequence (Length: 3051bp)
||pcDNA3.1-C-(k)DYK or customized vector
|Tag on pcDNA3.1-C-(k)DYK
||C terminal DYKDDDDK tags
|ORF Insert Method
||CloneEZ® Seamless cloning technology
||Homo sapiens (human)
||mastermind-like protein 1
||REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from D83785.1, AF221759.1 and
On Oct 2, 2008 this sequence version replaced gi:41350321.
Summary: This protein is the human homolog of mastermind, a
Drosophila protein that plays a role in the Notch signaling pathway
involved in cell-fate determination. There is in vitro evidence
that the human homolog forms a complex with the intracellular
portion of human Notch receptors and can increase expression of a
Notch-induced gene. This evidence supports its proposed function as
a transcriptional co-activator in the Notch signaling pathway.
[provided by RefSeq, Jul 2008].
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
Transcript exon combination :: D83785.1 [ECO:0000332]
RNAseq introns :: single sample supports all introns
COMPLETENESS: complete on the 3' end.