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NR1I3 nuclear receptor subfamily 1, group I, member 3 [Homo sapiens (human)]

Gene Symbol NR1I3
Entrez Gene ID 9970
Full Name nuclear receptor subfamily 1, group I, member 3
Synonyms CAR, CAR1, MB67
General protein information
Preferred Names
nuclear receptor subfamily 1 group I member 3
Names
nuclear receptor subfamily 1 group I member 3
constitutive active receptor
constitutive active response
orphan nuclear receptor MB67
orphan nuclear hormone receptor
constitutive androstane receptor
constitutive activator of retinoid response
constitutive androstane nuclear receptor variant 2
constitutive androstane nuclear receptor variant 3
constitutive androstane nuclear receptor variant 4
constitutive androstane nuclear receptor variant 5
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

1

1q23.3

Summary This gene encodes a member of the nuclear receptor superfamily, and is a key regulator of xenobiotic and endobiotic metabolism. The protein binds to DNA as a monomer or a heterodimer with the retinoid X receptor and regulates the transcription of target genes involved in drug metabolism and bilirubin clearance, such as cytochrome P450 family members. Unlike most nuclear receptors, this transcriptional regulator is constitutively active in the absence of ligand but is regulated by both agonists and inverse agonists. Ligand binding results in translocation of this protein to the nucleus, where it activates or represses target gene transcription. These ligands include bilirubin, a variety of foreign compounds, steroid hormones, and prescription drugs. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]. lac of sum
Disorder MIM:

603881

Disorder Html:





The following NR1I3 gene sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the NR1I3 gene which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu34912 XM_005245693 PREDICTED: Homo sapiens nuclear receptor subfamily 1, group I, member 3 (NR1I3), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $319
OHu34913 XM_005245694 PREDICTED: Homo sapiens nuclear receptor subfamily 1, group I, member 3 (NR1I3), transcript variant X2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $319
OHu63565 XM_011510237 PREDICTED: Homo sapiens nuclear receptor subfamily 1, group I, member 3 (NR1I3), transcript variant X3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $319
OHu34914 XM_005245697 PREDICTED: Homo sapiens nuclear receptor subfamily 1, group I, member 3 (NR1I3), transcript variant X4, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $319
OHu10438 NM_001077480 Homo sapiens nuclear receptor subfamily 1, group I, member 3 (NR1I3), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $379
OHu12022 NM_001077481 Homo sapiens nuclear receptor subfamily 1, group I, member 3 (NR1I3), transcript variant 4, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $309
OHu18640 NM_001077482 Homo sapiens nuclear receptor subfamily 1, group I, member 3 (NR1I3), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $299
OHu09461 NM_001077473 Homo sapiens nuclear receptor subfamily 1, group I, member 3 (NR1I3), transcript variant 12, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $309
OHu09511 NM_001077474 Homo sapiens nuclear receptor subfamily 1, group I, member 3 (NR1I3), transcript variant 8, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $309
OHu09441 NM_001077475 Homo sapiens nuclear receptor subfamily 1, group I, member 3 (NR1I3), transcript variant 15, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $199
OHu09388 NM_001077476 Homo sapiens nuclear receptor subfamily 1, group I, member 3 (NR1I3), transcript variant 13, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $309
OHu09464 NM_001077477 Homo sapiens nuclear receptor subfamily 1, group I, member 3 (NR1I3), transcript variant 14, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $309
OHu09477 NM_001077478 Homo sapiens nuclear receptor subfamily 1, group I, member 3 (NR1I3), transcript variant 7, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $289
OHu09520 NM_001077479 Homo sapiens nuclear receptor subfamily 1, group I, member 3 (NR1I3), transcript variant 10, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $309
OHu09517 NM_001077469 Homo sapiens nuclear receptor subfamily 1, group I, member 3 (NR1I3), transcript variant 6, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $289
OHu09315 NM_005122 Homo sapiens nuclear receptor subfamily 1, group I, member 3 (NR1I3), transcript variant 3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $289
OHu09474 NM_001077470 Homo sapiens nuclear receptor subfamily 1, group I, member 3 (NR1I3), transcript variant 11, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $309
OHu09332 NM_001077471 Homo sapiens nuclear receptor subfamily 1, group I, member 3 (NR1I3), transcript variant 5, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $309
OHu09423 NM_001077472 Homo sapiens nuclear receptor subfamily 1, group I, member 3 (NR1I3), transcript variant 9, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $309

*Business Day
**You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.


CloneID OHu34912
Accession Version XM_005245693.3 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1290bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector Document: User manual_GenEZ ORF Clone Products.pdf (pdf)
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags Document: MSDS_GenEZ ORF Clone Products.pdf (pdf)
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product nuclear receptor subfamily 1 group I member 3 isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_004487.20) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 12, 2015 this sequence version replaced gi:578801883. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
ATGAGTCACA AGGTTCCCAC CCACTGGAGT CCCTCCCCGT GTGCCACCAA CCAGCACTTT 
TGTCATGCTG GGAAAACCTC CCACCCAGGC CTTTGCCCTG AGTCCAGGGT CTGTGCCCTA
ACCCCACAGT CACTGAGAGC AACTGGAGGC CACATAAAAC AGACATCTCT TGTTTTCCAG
ATACTACGGG TCATAATCCC TAACTCCAAT CACTGGCAAC TCCTGAGATC AGAGGAAAAC
CAGCAACAGC GTGGGAGTTT GGGGAGAGGC ATTCCATACC AGATTCTGTG GCCTGCAGGT
GACATGCTGC CTAAGAGAAG CAGGAGAACA GTCAGCAAAA GCATTGGTCC CACCTGCCCC
TTTGCTGGAA GCTGTGAAGT CAGCAAGACT CAGAGGCGCC ACTGCCCAGC CTGCAGGTTG
CAGAAGTGCT TAGATGCTGG CATGAGGAAA GACATGATAC TGTCGGCAGA AGCCCTGGCA
TTGCGGCGAG CAAAGCAGGC CCAGCGGCGG GCACAGCAAA CACCTGTGCA ACTGAGTAAG
GAGCAAGAAG AGCTGATCCG GACACTCCTG GGGGCCCACA CCCGCCACAT GGGCACCATG
TTTGAACAGT TTGTGCAGTT TAGGCCTCCA GCTCATCTGT TCATCCATCA CCAGCCCTTG
CCCACCCTGG CCCCTGTGCT GCCTCTGGTC ACACACTTCG CAGACATCAA CACTTTCATG
GTACTGCAAG TCATCAAGTT TACTAAGGAC CTGCCCGTCT TCCGTTCCCT GCCCATTGAA
GACCAGATCT CCCTTCTCAA GGGAGCAGCT GTGGAAATCT GTCACATCGT ACTCAATACC
ACTTTCTGTC TCCAAACACA AAACTTCCTC TGCGGGCCTC TTCGCTACAC AATTGAAGAT
GGAGCCCGTG TATCTCCCAC AGTGGGGTTC CAGGTAGAGT TTTTGGAGTT GCTCTTTCAC
TTCCATGGAA CACTACGAAA ACTGCAGCTC CAAGAGCCTG AGTATGTGCT CTTGGCTGCC
ATGGCCCTCT TCTCTCCTGC TCCCTATCTT ACAGACCGAC CTGGAGTTAC CCAGAGAGAT
GAGATTGATC AGCTGCAAGA GGAGATGGCA CTGACTCTGC AAAGCTACAT CAAGGGCCAG
CAGCGAAGGC CCCGGGATCG GTTTCTGTAT GCGAAGTTGC TAGGCCTGCT GGCTGAGCTC
CGGAGCATTA ATGAGGCCTA CGGGTACCAA ATCCAGCACA TCCAGGGCCT GTCTGCCATG
ATGCCGCTGC TCCAGGAGAT CTGCAGCTGA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqXP_005245750.1
CDS236..1525
Misc Feature(1)557..697(+)
Misc Feature(2)560..694(+)
Misc Feature(3)590..649(+)
Misc Feature(4)767..1516(+)
Misc Feature(5)929..1456(+)
Misc Feature(6)968..1516(+)
Misc Feature(7)1184..1450(+)
Translation
Position Chain Variation Link
2 2 a, g dbSNP:190289526
51 51 c, t dbSNP:575353124
59 59 a, t dbSNP:774497785
82 82 a, g dbSNP:553372969
92 92 -, gcttgct dbSNP:773099338
96 96 g, t dbSNP:78525053
102 102 g, t dbSNP:112072259
106 106 a, t dbSNP:141726489
113 113 -, tctctc dbSNP:57652971
114 114 g, t dbSNP:34248246
131 131 -, ctct dbSNP:773872527
131 131 -, ct dbSNP:764569204
131 131 c, g dbSNP:77378469
134 134 -, ctct dbSNP:377140424
141 141 c, t dbSNP:564859038
170 170 g, t dbSNP:550108369
205 205 g, t dbSNP:545153199
214 214 a, g dbSNP:572996536
301 301 c, t dbSNP:553073071
313 313 c, t dbSNP:185863222
342 342 g, t dbSNP:35796551
426 426 c, t dbSNP:762782589
453 453 a, c dbSNP:555012220
454 454 a, g dbSNP:538519022
486 486 a, g dbSNP:568943207
498 498 c, g dbSNP:746849019
502 502 a, t dbSNP:780391609
510 510 c, t dbSNP:758722723
512 512 c, t dbSNP:750479350
526 526 a, g dbSNP:765416900
527 527 c, g dbSNP:757636106
528 528 c, t dbSNP:754360419
532 532 a, g dbSNP:764563799
536 536 a, g dbSNP:376555075
540 540 a, t dbSNP:372090555
547 547 c, t dbSNP:181499203
549 549 a, g dbSNP:188975149
555 555 a, g, t dbSNP:769343586
559 559 -, gag dbSNP:764025470
560 560 a, c dbSNP:755509541
564 564 -, c dbSNP:760565010
565 565 a, c dbSNP:777971759
579 579 c, t dbSNP:747349033
585 585 a, c dbSNP:780293934
586 586 -, c dbSNP:775526201
586 586 c, t dbSNP:756865381
587 587 a, c dbSNP:753425575
593 593 c, g dbSNP:763894632
595 595 -, cc dbSNP:767358929
595 595 c, g dbSNP:544741783
596 596 c, t dbSNP:201089859
599 599 a, g dbSNP:752292550
600 600 c, t dbSNP:767517431
607 607 c, g dbSNP:759410250
608 608 g, t dbSNP:774131812
622 622 a, g dbSNP:766084148
627 627 a, t dbSNP:762865830
630 630 a, g dbSNP:142842008
631 631 g, t dbSNP:138077816
632 632 c, t dbSNP:748184864
633 633 a, g dbSNP:148277311
639 639 a, g, t dbSNP:747474209
640 640 a, c, t dbSNP:758672635
647 647 a, t dbSNP:565978374
648 648 g, t dbSNP:777533188
652 652 c, g dbSNP:755856811
664 664 a, c dbSNP:200078573
669 669 a, g dbSNP:112022118
677 677 a, g dbSNP:752198862
679 679 a, g dbSNP:548963536
684 684 -, aa dbSNP:759027156
695 695 c, t dbSNP:779436154
699 699 c, t dbSNP:373897043
700 700 a, g dbSNP:2307425
703 703 a, g dbSNP:781053597
709 709 c, g dbSNP:35205211
713 713 a, g dbSNP:751122638
720 720 a, g dbSNP:376162036
723 723 a, g dbSNP:531442743
731 731 a, c dbSNP:750159568
734 734 a, g dbSNP:563503102
739 739 a, g dbSNP:141229326
739 739 -, g dbSNP:776959559
740 740 c, t dbSNP:34161743
741 741 a, g dbSNP:368339212
744 744 a, g dbSNP:375295397
750 750 a, g dbSNP:764422186
753 753 a, g dbSNP:760638672
755 755 a, t dbSNP:775668216
762 762 c, t dbSNP:568686293
769 769 -, gagt dbSNP:768961218
782 782 a, g dbSNP:772403818
784 784 -, aga dbSNP:747407591
794 794 c, t dbSNP:376834028
795 795 a, g dbSNP:545723392
802 802 c, t dbSNP:146059027
803 803 c, g dbSNP:139629845
805 805 a, g dbSNP:370461642
807 807 a, g dbSNP:377243932
809 809 c, g dbSNP:768389092
813 813 a, c dbSNP:746456274
815 815 a, c dbSNP:779628611
816 816 c, g, t dbSNP:372603248
818 818 c, t dbSNP:778879440
819 819 a, g dbSNP:139473535
823 823 c, t dbSNP:753669717
825 825 c, g, t dbSNP:756377863
833 833 a, g dbSNP:752656803
834 834 c, t dbSNP:767632630
848 848 a, g dbSNP:149303773
854 854 c, t dbSNP:774980216
870 870 a, g dbSNP:752954187
877 877 c, t dbSNP:150598676
880 880 c, g dbSNP:755079453
882 882 a, g dbSNP:751720819
891 891 c, g dbSNP:369446796
895 895 a, g dbSNP:138159825
903 903 c, t dbSNP:773380358
906 906 c, t dbSNP:202054823
910 910 a, t dbSNP:762142599
919 919 c, t dbSNP:775185492
928 928 a, g, t dbSNP:745338458
934 934 c, t dbSNP:773871551
935 935 a, g dbSNP:375116822
937 937 a, c, t dbSNP:777632204
940 940 c, t dbSNP:367668454
948 948 c, t dbSNP:747937878
950 950 g, t dbSNP:781436406
954 954 c, t dbSNP:41270857
965 965 a, g dbSNP:751634864
981 981 -, a dbSNP:751138627
983 983 a, g dbSNP:780283429
984 984 a, c dbSNP:758616441
988 988 a, g dbSNP:750927922
991 991 c, t dbSNP:2307424
992 992 a, g dbSNP:143067018
998 998 c, t dbSNP:754182730
999 999 a, g dbSNP:767105877
1006 1006 a, g, t dbSNP:754170136
1007 1007 c, t dbSNP:764443927
1009 1009 c, t dbSNP:761088863
1011 1011 c, t dbSNP:564859096
1028 1028 c, g dbSNP:766064438
1031 1031 c, t dbSNP:772286234
1062 1062 c, t dbSNP:762489220
1064 1064 a, g dbSNP:772619920
1065 1065 g, t dbSNP:769715201
1079 1079 c, t dbSNP:746125471
1086 1086 a, t dbSNP:761662278
1093 1093 a, c dbSNP:776774308
1108 1108 c, t dbSNP:544805520
1109 1109 a, g dbSNP:746849037
1111 1111 a, g dbSNP:780391681
1112 1112 c, t dbSNP:772210168
1118 1118 c, t dbSNP:745909079
1131 1131 a, c dbSNP:778869769
1141 1141 c, t dbSNP:149864108
1143 1143 a, g dbSNP:145025028
1144 1144 c, t dbSNP:559151462
1162 1162 a, g dbSNP:774699125
1164 1164 g, t dbSNP:770895742
1175 1175 c, t dbSNP:146624074
1176 1176 c, t dbSNP:778217125
1181 1181 a, g dbSNP:756640389
1185 1185 -, t dbSNP:751049065
1190 1190 -, tttcacttc dbSNP:765857067
1191 1191 c, t dbSNP:398122411
1199 1199 c, t dbSNP:748454600
1200 1200 a, g dbSNP:201406656
1205 1205 a, g dbSNP:781415233
1208 1208 c, t dbSNP:755439721
1211 1211 a, c, g, t dbSNP:144211465
1212 1212 a, g dbSNP:753430504
1239 1239 a, g dbSNP:764070169
1244 1244 c, g dbSNP:760698101
1256 1256 a, g dbSNP:113800307
1257 1257 a, t dbSNP:775354782
1258 1258 a, g dbSNP:767209723
1271 1271 a, c dbSNP:1140627
1272 1272 c, t dbSNP:759426392
1273 1273 a, t dbSNP:66915105
1274 1274 a, g dbSNP:774408356
1283 1283 c, t dbSNP:777631690
1286 1286 a, g dbSNP:754957464
1291 1291 c, g, t dbSNP:201028035
1292 1292 c, t dbSNP:762797428
1293 1293 a, g dbSNP:142330499
1298 1298 a, g dbSNP:765481537
1309 1309 a, g dbSNP:761756373
1312 1312 a, g dbSNP:776791009
1316 1316 g, t dbSNP:768982496
1318 1318 c, g dbSNP:761248912
1320 1320 c, t dbSNP:775926630
1327 1327 c, g dbSNP:772550648
1338 1338 -, a dbSNP:769443369
1344 1344 c, t dbSNP:746281035
1372 1372 a, c dbSNP:199534928
1379 1379 c, t dbSNP:769594436
1380 1380 a, g dbSNP:200523878
1388 1388 c, t dbSNP:148675838
1389 1389 a, g dbSNP:754515980
1394 1394 c, t dbSNP:143583938
1395 1395 a, g dbSNP:114879683
1396 1396 g, t dbSNP:760125469
1404 1404 a, t dbSNP:775065775
1407 1407 c, t dbSNP:200408085
1408 1408 a, g dbSNP:36017137
1411 1411 c, g dbSNP:776318584
1412 1412 c, t dbSNP:768226364
1414 1414 a, g dbSNP:373127924
1416 1416 c, t dbSNP:774991039
1417 1417 a, c dbSNP:150124500
1418 1418 a, c, g, t dbSNP:2307414
1432 1432 a, g dbSNP:745800174
1436 1436 c, t dbSNP:369817002
1437 1437 a, g dbSNP:376397342
1439 1439 a, g dbSNP:770736555
1446 1446 a, t dbSNP:139722132
1451 1451 a, g dbSNP:749076282
1456 1456 c, t dbSNP:79799851
1457 1457 a, g dbSNP:756304664
1470 1470 a, g dbSNP:752758736
1471 1471 c, g dbSNP:781417564
1472 1472 c, t dbSNP:373882046
1478 1478 -, cagggcc dbSNP:779493594
1481 1481 c, g dbSNP:752094371
1500 1500 c, t dbSNP:758748494
1501 1501 a, g dbSNP:200228217
1504 1504 g, t dbSNP:141332323
1510 1510 a, g dbSNP:141389397
1516 1516 a, c dbSNP:369311646
1521 1521 a, c, g, t dbSNP:771557332
1527 1527 a, g dbSNP:140549301
1530 1530 a, g dbSNP:774313084
1532 1532 g, t dbSNP:376510791
1533 1533 c, t dbSNP:147849659
1538 1538 g, t dbSNP:777436441
1545 1545 c, t dbSNP:769779489
1553 1553 a, t dbSNP:748367918
1565 1565 a, c dbSNP:781617937
1574 1574 -, c dbSNP:771091045
1576 1576 a, g dbSNP:755081784
1583 1583 a, g dbSNP:751722876
1588 1588 c, t dbSNP:780564353
1589 1589 a, g dbSNP:755279262
1591 1591 -, t dbSNP:749380602
1594 1594 a, g dbSNP:3813629
1596 1596 c, t dbSNP:537248708
1609 1609 a, c, t dbSNP:201243903
1610 1610 a, g dbSNP:34645321
1611 1611 a, c, g dbSNP:2307416
1617 1617 a, c dbSNP:752324753
1618 1618 -, a dbSNP:778081793
1625 1625 c, t dbSNP:767195966
1630 1630 g, t dbSNP:759006086
1632 1632 c, t dbSNP:773748252
1639 1639 a, g dbSNP:766275202
1648 1648 a, g dbSNP:368521829

Target ORF information:

RefSeq Version XM_005245693
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens nuclear receptor subfamily 1, group I, member 3 (NR1I3), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_005245693

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
ATGAGTCACA AGGTTCCCAC CCACTGGAGT CCCTCCCCGT GTGCCACCAA CCAGCACTTT 
TGTCATGCTG GGAAAACCTC CCACCCAGGC CTTTGCCCTG AGTCCAGGGT CTGTGCCCTA
ACCCCACAGT CACTGAGAGC AACTGGAGGC CACATAAAAC AGACATCTCT TGTTTTCCAG
ATACTACGGG TCATAATCCC TAACTCCAAT CACTGGCAAC TCCTGAGATC AGAGGAAAAC
CAGCAACAGC GTGGGAGTTT GGGGAGAGGC ATTCCATACC AGATTCTGTG GCCTGCAGGT
GACATGCTGC CTAAGAGAAG CAGGAGAACA GTCAGCAAAA GCATTGGTCC CACCTGCCCC
TTTGCTGGAA GCTGTGAAGT CAGCAAGACT CAGAGGCGCC ACTGCCCAGC CTGCAGGTTG
CAGAAGTGCT TAGATGCTGG CATGAGGAAA GACATGATAC TGTCGGCAGA AGCCCTGGCA
TTGCGGCGAG CAAAGCAGGC CCAGCGGCGG GCACAGCAAA CACCTGTGCA ACTGAGTAAG
GAGCAAGAAG AGCTGATCCG GACACTCCTG GGGGCCCACA CCCGCCACAT GGGCACCATG
TTTGAACAGT TTGTGCAGTT TAGGCCTCCA GCTCATCTGT TCATCCATCA CCAGCCCTTG
CCCACCCTGG CCCCTGTGCT GCCTCTGGTC ACACACTTCG CAGACATCAA CACTTTCATG
GTACTGCAAG TCATCAAGTT TACTAAGGAC CTGCCCGTCT TCCGTTCCCT GCCCATTGAA
GACCAGATCT CCCTTCTCAA GGGAGCAGCT GTGGAAATCT GTCACATCGT ACTCAATACC
ACTTTCTGTC TCCAAACACA AAACTTCCTC TGCGGGCCTC TTCGCTACAC AATTGAAGAT
GGAGCCCGTG TATCTCCCAC AGTGGGGTTC CAGGTAGAGT TTTTGGAGTT GCTCTTTCAC
TTCCATGGAA CACTACGAAA ACTGCAGCTC CAAGAGCCTG AGTATGTGCT CTTGGCTGCC
ATGGCCCTCT TCTCTCCTGC TCCCTATCTT ACAGACCGAC CTGGAGTTAC CCAGAGAGAT
GAGATTGATC AGCTGCAAGA GGAGATGGCA CTGACTCTGC AAAGCTACAT CAAGGGCCAG
CAGCGAAGGC CCCGGGATCG GTTTCTGTAT GCGAAGTTGC TAGGCCTGCT GGCTGAGCTC
CGGAGCATTA ATGAGGCCTA CGGGTACCAA ATCCAGCACA TCCAGGGCCT GTCTGCCATG
ATGCCGCTGC TCCAGGAGAT CTGCAGCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu34913
Accession Version XM_005245694.3 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1275bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector Document: User manual_GenEZ ORF Clone Products.pdf (pdf)
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags Document: MSDS_GenEZ ORF Clone Products.pdf (pdf)
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product nuclear receptor subfamily 1 group I member 3 isoform X2
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_004487.20) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 12, 2015 this sequence version replaced gi:578801884. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
ATGAGTCACA AGGTTCCCAC CCACTGGAGT CCCTCCCCGT GTGCCACCAA CCAGCACTTT 
TGTCATGCTG GGAAAACCTC CCACCCAGGC CTTTGCCCTG AGTCCAGGGT CTGTGCCCTA
ACCCCACAGT CACTGAGAGC AACTGGAGGC CACATAAAAC AGACATCTCT TGTTTTCCAG
ATACTACGGG TCATAATCCC TAACTCCAAT CACTGGCAAC TCCTGAGATC AGAGGAAAAC
CAGCAACAGC GTGGGAGTTT GGGGAGAGGC ATTCCATACC AGATTCTGTG GCCTGCAGGT
GACATGCTGC CTAAGAGAAG CAGGAGAACA GTCAGCAAAA GCATTGGTCC CACCTGCCCC
TTTGCTGGAA GCTGTGAAGT CAGCAAGACT CAGAGGCGCC ACTGCCCAGC CTGCAGGTTG
CAGAAGTGCT TAGATGCTGG CATGAGGAAA GACATGATAC TGTCGGCAGA AGCCCTGGCA
TTGCGGCGAG CAAAGCAGGC CCAGCGGCGG GCACAGCAAA CACCTGTGCA ACTGAGTAAG
GAGCAAGAAG AGCTGATCCG GACACTCCTG GGGGCCCACA CCCGCCACAT GGGCACCATG
TTTGAACAGT TTGTGCAGTT TAGGCCTCCA GCTCATCTGT TCATCCATCA CCAGCCCTTG
CCCACCCTGG CCCCTGTGCT GCCTCTGGTC ACACACTTCG CAGACATCAA CACTTTCATG
GTACTGCAAG TCATCAAGTT TACTAAGGAC CTGCCCGTCT TCCGTTCCCT GCCCATTGAA
GACCAGATCT CCCTTCTCAA GGGAGCAGCT GTGGAAATCT GTCACATCGT ACTCAATACC
ACTTTCTGTC TCCAAACACA AAACTTCCTC TGCGGGCCTC TTCGCTACAC AATTGAAGAT
GGAGCCCGTG TATCTCCCAC AGTGGGGTTC CAGGTAGAGT TTTTGGAGTT GCTCTTTCAC
TTCCATGGAA CACTACGAAA ACTGCAGCTC CAAGAGCCTG AGTATGTGCT CTTGGCTGCC
ATGGCCCTCT TCTCTCCTGA CCGACCTGGA GTTACCCAGA GAGATGAGAT TGATCAGCTG
CAAGAGGAGA TGGCACTGAC TCTGCAAAGC TACATCAAGG GCCAGCAGCG AAGGCCCCGG
GATCGGTTTC TGTATGCGAA GTTGCTAGGC CTGCTGGCTG AGCTCCGGAG CATTAATGAG
GCCTACGGGT ACCAAATCCA GCACATCCAG GGCCTGTCTG CCATGATGCC GCTGCTCCAG
GAGATCTGCA GCTGA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqXP_005245751.1
CDS235..1509
Misc Feature(1)556..696(+)
Misc Feature(2)559..693(+)
Misc Feature(3)589..648(+)
Misc Feature(4)766..1500(+)
Misc Feature(5)928..1440(+)
Misc Feature(6)967..1500(+)
Misc Feature(7)1183..1434(+)
Translation
Position Chain Variation Link
1 1 a, g dbSNP:190289526
50 50 c, t dbSNP:575353124
58 58 a, t dbSNP:774497785
81 81 a, g dbSNP:553372969
91 91 -, gcttgct dbSNP:773099338
95 95 g, t dbSNP:78525053
101 101 g, t dbSNP:112072259
105 105 a, t dbSNP:141726489
112 112 -, tctctc dbSNP:57652971
113 113 g, t dbSNP:34248246
130 130 -, ctct dbSNP:773872527
130 130 -, ct dbSNP:764569204
130 130 c, g dbSNP:77378469
133 133 -, ctct dbSNP:377140424
140 140 c, t dbSNP:564859038
169 169 g, t dbSNP:550108369
204 204 g, t dbSNP:545153199
213 213 a, g dbSNP:572996536
300 300 c, t dbSNP:553073071
312 312 c, t dbSNP:185863222
341 341 g, t dbSNP:35796551
425 425 c, t dbSNP:762782589
452 452 a, c dbSNP:555012220
453 453 a, g dbSNP:538519022
485 485 a, g dbSNP:568943207
497 497 c, g dbSNP:746849019
501 501 a, t dbSNP:780391609
509 509 c, t dbSNP:758722723
511 511 c, t dbSNP:750479350
525 525 a, g dbSNP:765416900
526 526 c, g dbSNP:757636106
527 527 c, t dbSNP:754360419
531 531 a, g dbSNP:764563799
535 535 a, g dbSNP:376555075
539 539 a, t dbSNP:372090555
546 546 c, t dbSNP:181499203
548 548 a, g dbSNP:188975149
554 554 a, g, t dbSNP:769343586
558 558 -, gag dbSNP:764025470
559 559 a, c dbSNP:755509541
563 563 -, c dbSNP:760565010
564 564 a, c dbSNP:777971759
578 578 c, t dbSNP:747349033
584 584 a, c dbSNP:780293934
585 585 -, c dbSNP:775526201
585 585 c, t dbSNP:756865381
586 586 a, c dbSNP:753425575
592 592 c, g dbSNP:763894632
594 594 -, cc dbSNP:767358929
594 594 c, g dbSNP:544741783
595 595 c, t dbSNP:201089859
598 598 a, g dbSNP:752292550
599 599 c, t dbSNP:767517431
606 606 c, g dbSNP:759410250
607 607 g, t dbSNP:774131812
621 621 a, g dbSNP:766084148
626 626 a, t dbSNP:762865830
629 629 a, g dbSNP:142842008
630 630 g, t dbSNP:138077816
631 631 c, t dbSNP:748184864
632 632 a, g dbSNP:148277311
638 638 a, g, t dbSNP:747474209
639 639 a, c, t dbSNP:758672635
646 646 a, t dbSNP:565978374
647 647 g, t dbSNP:777533188
651 651 c, g dbSNP:755856811
663 663 a, c dbSNP:200078573
668 668 a, g dbSNP:112022118
676 676 a, g dbSNP:752198862
678 678 a, g dbSNP:548963536
683 683 -, aa dbSNP:759027156
694 694 c, t dbSNP:779436154
698 698 c, t dbSNP:373897043
699 699 a, g dbSNP:2307425
702 702 a, g dbSNP:781053597
708 708 c, g dbSNP:35205211
712 712 a, g dbSNP:751122638
719 719 a, g dbSNP:376162036
722 722 a, g dbSNP:531442743
730 730 a, c dbSNP:750159568
733 733 a, g dbSNP:563503102
738 738 a, g dbSNP:141229326
738 738 -, g dbSNP:776959559
739 739 c, t dbSNP:34161743
740 740 a, g dbSNP:368339212
743 743 a, g dbSNP:375295397
749 749 a, g dbSNP:764422186
752 752 a, g dbSNP:760638672
754 754 a, t dbSNP:775668216
761 761 c, t dbSNP:568686293
768 768 -, gagt dbSNP:768961218
781 781 a, g dbSNP:772403818
783 783 -, aga dbSNP:747407591
793 793 c, t dbSNP:376834028
794 794 a, g dbSNP:545723392
801 801 c, t dbSNP:146059027
802 802 c, g dbSNP:139629845
804 804 a, g dbSNP:370461642
806 806 a, g dbSNP:377243932
808 808 c, g dbSNP:768389092
812 812 a, c dbSNP:746456274
814 814 a, c dbSNP:779628611
815 815 c, g, t dbSNP:372603248
817 817 c, t dbSNP:778879440
818 818 a, g dbSNP:139473535
822 822 c, t dbSNP:753669717
824 824 c, g, t dbSNP:756377863
832 832 a, g dbSNP:752656803
833 833 c, t dbSNP:767632630
847 847 a, g dbSNP:149303773
853 853 c, t dbSNP:774980216
869 869 a, g dbSNP:752954187
876 876 c, t dbSNP:150598676
879 879 c, g dbSNP:755079453
881 881 a, g dbSNP:751720819
890 890 c, g dbSNP:369446796
894 894 a, g dbSNP:138159825
902 902 c, t dbSNP:773380358
905 905 c, t dbSNP:202054823
909 909 a, t dbSNP:762142599
918 918 c, t dbSNP:775185492
927 927 a, g, t dbSNP:745338458
933 933 c, t dbSNP:773871551
934 934 a, g dbSNP:375116822
936 936 a, c, t dbSNP:777632204
939 939 c, t dbSNP:367668454
947 947 c, t dbSNP:747937878
949 949 g, t dbSNP:781436406
953 953 c, t dbSNP:41270857
964 964 a, g dbSNP:751634864
980 980 -, a dbSNP:751138627
982 982 a, g dbSNP:780283429
983 983 a, c dbSNP:758616441
987 987 a, g dbSNP:750927922
990 990 c, t dbSNP:2307424
991 991 a, g dbSNP:143067018
997 997 c, t dbSNP:754182730
998 998 a, g dbSNP:767105877
1005 1005 a, g, t dbSNP:754170136
1006 1006 c, t dbSNP:764443927
1008 1008 c, t dbSNP:761088863
1010 1010 c, t dbSNP:564859096
1027 1027 c, g dbSNP:766064438
1030 1030 c, t dbSNP:772286234
1061 1061 c, t dbSNP:762489220
1063 1063 a, g dbSNP:772619920
1064 1064 g, t dbSNP:769715201
1078 1078 c, t dbSNP:746125471
1085 1085 a, t dbSNP:761662278
1092 1092 a, c dbSNP:776774308
1107 1107 c, t dbSNP:544805520
1108 1108 a, g dbSNP:746849037
1110 1110 a, g dbSNP:780391681
1111 1111 c, t dbSNP:772210168
1117 1117 c, t dbSNP:745909079
1130 1130 a, c dbSNP:778869769
1140 1140 c, t dbSNP:149864108
1142 1142 a, g dbSNP:145025028
1143 1143 c, t dbSNP:559151462
1161 1161 a, g dbSNP:774699125
1163 1163 g, t dbSNP:770895742
1174 1174 c, t dbSNP:146624074
1175 1175 c, t dbSNP:778217125
1180 1180 a, g dbSNP:756640389
1184 1184 -, t dbSNP:751049065
1189 1189 -, tttcacttc dbSNP:765857067
1190 1190 c, t dbSNP:398122411
1198 1198 c, t dbSNP:748454600
1199 1199 a, g dbSNP:201406656
1204 1204 a, g dbSNP:781415233
1207 1207 c, t dbSNP:755439721
1210 1210 a, c, g, t dbSNP:144211465
1211 1211 a, g dbSNP:753430504
1238 1238 a, g dbSNP:764070169
1243 1243 c, g dbSNP:760698101
1255 1255 a, g dbSNP:113800307
1256 1256 a, t dbSNP:775354782
1257 1257 a, g dbSNP:767209723
1270 1270 a, c dbSNP:1140627
1271 1271 c, t dbSNP:759426392
1272 1272 a, t dbSNP:66915105
1273 1273 a, g dbSNP:774408356
1275 1275 c, g, t dbSNP:201028035
1276 1276 c, t dbSNP:762797428
1277 1277 a, g dbSNP:142330499
1282 1282 a, g dbSNP:765481537
1293 1293 a, g dbSNP:761756373
1296 1296 a, g dbSNP:776791009
1300 1300 g, t dbSNP:768982496
1302 1302 c, g dbSNP:761248912
1304 1304 c, t dbSNP:775926630
1311 1311 c, g dbSNP:772550648
1322 1322 -, a dbSNP:769443369
1328 1328 c, t dbSNP:746281035
1356 1356 a, c dbSNP:199534928
1363 1363 c, t dbSNP:769594436
1364 1364 a, g dbSNP:200523878
1372 1372 c, t dbSNP:148675838
1373 1373 a, g dbSNP:754515980
1378 1378 c, t dbSNP:143583938
1379 1379 a, g dbSNP:114879683
1380 1380 g, t dbSNP:760125469
1388 1388 a, t dbSNP:775065775
1391 1391 c, t dbSNP:200408085
1392 1392 a, g dbSNP:36017137
1395 1395 c, g dbSNP:776318584
1396 1396 c, t dbSNP:768226364
1398 1398 a, g dbSNP:373127924
1400 1400 c, t dbSNP:774991039
1401 1401 a, c dbSNP:150124500
1402 1402 a, c, g, t dbSNP:2307414
1416 1416 a, g dbSNP:745800174
1420 1420 c, t dbSNP:369817002
1421 1421 a, g dbSNP:376397342
1423 1423 a, g dbSNP:770736555
1430 1430 a, t dbSNP:139722132
1435 1435 a, g dbSNP:749076282
1440 1440 c, t dbSNP:79799851
1441 1441 a, g dbSNP:756304664
1454 1454 a, g dbSNP:752758736
1455 1455 c, g dbSNP:781417564
1456 1456 c, t dbSNP:373882046
1462 1462 -, cagggcc dbSNP:779493594
1465 1465 c, g dbSNP:752094371
1484 1484 c, t dbSNP:758748494
1485 1485 a, g dbSNP:200228217
1488 1488 g, t dbSNP:141332323
1494 1494 a, g dbSNP:141389397
1500 1500 a, c dbSNP:369311646
1505 1505 a, c, g, t dbSNP:771557332
1511 1511 a, g dbSNP:140549301
1514 1514 a, g dbSNP:774313084
1516 1516 g, t dbSNP:376510791
1517 1517 c, t dbSNP:147849659
1522 1522 g, t dbSNP:777436441
1529 1529 c, t dbSNP:769779489
1537 1537 a, t dbSNP:748367918
1549 1549 a, c dbSNP:781617937
1558 1558 -, c dbSNP:771091045
1560 1560 a, g dbSNP:755081784
1567 1567 a, g dbSNP:751722876
1572 1572 c, t dbSNP:780564353
1573 1573 a, g dbSNP:755279262
1575 1575 -, t dbSNP:749380602
1578 1578 a, g dbSNP:3813629
1580 1580 c, t dbSNP:537248708
1593 1593 a, c, t dbSNP:201243903
1594 1594 a, g dbSNP:34645321
1595 1595 a, c, g dbSNP:2307416
1601 1601 a, c dbSNP:752324753
1602 1602 -, a dbSNP:778081793
1609 1609 c, t dbSNP:767195966
1614 1614 g, t dbSNP:759006086
1616 1616 c, t dbSNP:773748252
1623 1623 a, g dbSNP:766275202
1632 1632 a, g dbSNP:368521829

Target ORF information:

RefSeq Version XM_005245694
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens nuclear receptor subfamily 1, group I, member 3 (NR1I3), transcript variant X2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_005245694

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
ATGAGTCACA AGGTTCCCAC CCACTGGAGT CCCTCCCCGT GTGCCACCAA CCAGCACTTT 
TGTCATGCTG GGAAAACCTC CCACCCAGGC CTTTGCCCTG AGTCCAGGGT CTGTGCCCTA
ACCCCACAGT CACTGAGAGC AACTGGAGGC CACATAAAAC AGACATCTCT TGTTTTCCAG
ATACTACGGG TCATAATCCC TAACTCCAAT CACTGGCAAC TCCTGAGATC AGAGGAAAAC
CAGCAACAGC GTGGGAGTTT GGGGAGAGGC ATTCCATACC AGATTCTGTG GCCTGCAGGT
GACATGCTGC CTAAGAGAAG CAGGAGAACA GTCAGCAAAA GCATTGGTCC CACCTGCCCC
TTTGCTGGAA GCTGTGAAGT CAGCAAGACT CAGAGGCGCC ACTGCCCAGC CTGCAGGTTG
CAGAAGTGCT TAGATGCTGG CATGAGGAAA GACATGATAC TGTCGGCAGA AGCCCTGGCA
TTGCGGCGAG CAAAGCAGGC CCAGCGGCGG GCACAGCAAA CACCTGTGCA ACTGAGTAAG
GAGCAAGAAG AGCTGATCCG GACACTCCTG GGGGCCCACA CCCGCCACAT GGGCACCATG
TTTGAACAGT TTGTGCAGTT TAGGCCTCCA GCTCATCTGT TCATCCATCA CCAGCCCTTG
CCCACCCTGG CCCCTGTGCT GCCTCTGGTC ACACACTTCG CAGACATCAA CACTTTCATG
GTACTGCAAG TCATCAAGTT TACTAAGGAC CTGCCCGTCT TCCGTTCCCT GCCCATTGAA
GACCAGATCT CCCTTCTCAA GGGAGCAGCT GTGGAAATCT GTCACATCGT ACTCAATACC
ACTTTCTGTC TCCAAACACA AAACTTCCTC TGCGGGCCTC TTCGCTACAC AATTGAAGAT
GGAGCCCGTG TATCTCCCAC AGTGGGGTTC CAGGTAGAGT TTTTGGAGTT GCTCTTTCAC
TTCCATGGAA CACTACGAAA ACTGCAGCTC CAAGAGCCTG AGTATGTGCT CTTGGCTGCC
ATGGCCCTCT TCTCTCCTGA CCGACCTGGA GTTACCCAGA GAGATGAGAT TGATCAGCTG
CAAGAGGAGA TGGCACTGAC TCTGCAAAGC TACATCAAGG GCCAGCAGCG AAGGCCCCGG
GATCGGTTTC TGTATGCGAA GTTGCTAGGC CTGCTGGCTG AGCTCCGGAG CATTAATGAG
GCCTACGGGT ACCAAATCCA GCACATCCAG GGCCTGTCTG CCATGATGCC GCTGCTCCAG
GAGATCTGCA GCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu63565
Accession Version XM_011510237.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1161bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector Document: User manual_GenEZ ORF Clone Products.pdf (pdf)
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags Document: MSDS_GenEZ ORF Clone Products.pdf (pdf)
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product nuclear receptor subfamily 1 group I member 3 isoform X3
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_004487.20) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
ATGAGTCACA AGGTTCCCAC CCACTGGAGT CCCTCCCCGT GTGCCACCAA CCAGCACTTT 
TGTCATGCTG GGAAAACCTC CCACCCAGGC CTTTGCCCTG AGTCCAGGGT CTGTGCCCTA
ACCCCACAGT CACTGAGAGC AACTGGAGGC CACATAAAAC AGACATCTCT TGTTTTCCAG
ATACTACGGG TCATAATCCC TAACTCCAAT CACTGGCAAC TCCTGAGATC AGAGGAAAAC
CAGCAACAGC GTGGGAGTTT GGGGAGAGGC ATTCCATACC AGATTCTGTG GCCTGCAGGT
GACATGCTGC CTAAGAGAAG CAGGAGAACA GTCAGCAAAA GCATTGGTCC CACCTGCCCC
TTTGCTGGAA GCTGTGAAGT CAGCAAGACT CAGAGGCGCC ACTGCCCAGC CTGCAGGTTG
CAGAAGTGCT TAGATGCTGG CATGAGGAAA GACATGATAC TGTCGGCAGA AGCCCTGGCA
TTGCGGCGAG CAAAGCAGGC CCAGCGGCGG GCACAGCAAA CACCTGTGCA ACTGAGTAAG
GAGCAAGAAG AGCTGATCCG GACACTCCTG GGGGCCCACA CCCGCCACAT GGGCACCATG
TTTGAACAGT TTGTGCAGTT TAGGCCTCCA GCTCATCTGT TCATCCATCA CCAGCCCTTG
CCCACCCTGG CCCCTGTGCT GCCTCTGGTC ACACACTTCG CAGACATCAA CACTTTCATG
GTACTGCAAG TCATCAAGTT TACTAAGGAC CTGCCCGTCT TCCGTTCCCT GCCCATTGAA
GACCAGATCT CCCTTCTCAA GGGAGCAGCT GTGGAAATCT GTCACATCGT ACTCAATACC
ACTTTCTGTC TCCAAACACA AAACTTCCTC TGCGGGCCTC TTCGCTACAC AATTGAAGAT
GGAGCCCGTG CTCCCTATCT TACAGACCGA CCTGGAGTTA CCCAGAGAGA TGAGATTGAT
CAGCTGCAAG AGGAGATGGC ACTGACTCTG CAAAGCTACA TCAAGGGCCA GCAGCGAAGG
CCCCGGGATC GGTTTCTGTA TGCGAAGTTG CTAGGCCTGC TGGCTGAGCT CCGGAGCATT
AATGAGGCCT ACGGGTACCA AATCCAGCAC ATCCAGGGCC TGTCTGCCAT GATGCCGCTG
CTCCAGGAGA TCTGCAGCTG A
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqXP_011508539.1
CDS234..1394
Misc Feature(1)555..695(+)
Misc Feature(2)558..692(+)
Misc Feature(3)588..647(+)
Misc Feature(4)765..1385(+)
Misc Feature(5)930..1151(+)
Misc Feature(6)957..1034(+)
Translation
Position Chain Variation Link
49 49 c, t dbSNP:575353124
57 57 a, t dbSNP:774497785
80 80 a, g dbSNP:553372969
90 90 -, gcttgct dbSNP:773099338
94 94 g, t dbSNP:78525053
100 100 g, t dbSNP:112072259
104 104 a, t dbSNP:141726489
111 111 -, tctctc dbSNP:57652971
112 112 g, t dbSNP:34248246
129 129 -, ctct dbSNP:773872527
129 129 -, ct dbSNP:764569204
129 129 c, g dbSNP:77378469
132 132 -, ctct dbSNP:377140424
139 139 c, t dbSNP:564859038
168 168 g, t dbSNP:550108369
203 203 g, t dbSNP:545153199
212 212 a, g dbSNP:572996536
299 299 c, t dbSNP:553073071
311 311 c, t dbSNP:185863222
340 340 g, t dbSNP:35796551
424 424 c, t dbSNP:762782589
451 451 a, c dbSNP:555012220
452 452 a, g dbSNP:538519022
484 484 a, g dbSNP:568943207
496 496 c, g dbSNP:746849019
500 500 a, t dbSNP:780391609
508 508 c, t dbSNP:758722723
510 510 c, t dbSNP:750479350
524 524 a, g dbSNP:765416900
525 525 c, g dbSNP:757636106
526 526 c, t dbSNP:754360419
530 530 a, g dbSNP:764563799
534 534 a, g dbSNP:376555075
538 538 a, t dbSNP:372090555
545 545 c, t dbSNP:181499203
547 547 a, g dbSNP:188975149
553 553 a, g, t dbSNP:769343586
557 557 -, gag dbSNP:764025470
558 558 a, c dbSNP:755509541
562 562 -, c dbSNP:760565010
563 563 a, c dbSNP:777971759
577 577 c, t dbSNP:747349033
583 583 a, c dbSNP:780293934
584 584 -, c dbSNP:775526201
584 584 c, t dbSNP:756865381
585 585 a, c dbSNP:753425575
591 591 c, g dbSNP:763894632
593 593 -, cc dbSNP:767358929
593 593 c, g dbSNP:544741783
594 594 c, t dbSNP:201089859
597 597 a, g dbSNP:752292550
598 598 c, t dbSNP:767517431
605 605 c, g dbSNP:759410250
606 606 g, t dbSNP:774131812
620 620 a, g dbSNP:766084148
625 625 a, t dbSNP:762865830
628 628 a, g dbSNP:142842008
629 629 g, t dbSNP:138077816
630 630 c, t dbSNP:748184864
631 631 a, g dbSNP:148277311
637 637 a, g, t dbSNP:747474209
638 638 a, c, t dbSNP:758672635
645 645 a, t dbSNP:565978374
646 646 g, t dbSNP:777533188
650 650 c, g dbSNP:755856811
662 662 a, c dbSNP:200078573
667 667 a, g dbSNP:112022118
675 675 a, g dbSNP:752198862
677 677 a, g dbSNP:548963536
682 682 -, aa dbSNP:759027156
693 693 c, t dbSNP:779436154
697 697 c, t dbSNP:373897043
698 698 a, g dbSNP:2307425
701 701 a, g dbSNP:781053597
707 707 c, g dbSNP:35205211
711 711 a, g dbSNP:751122638
718 718 a, g dbSNP:376162036
721 721 a, g dbSNP:531442743
729 729 a, c dbSNP:750159568
732 732 a, g dbSNP:563503102
737 737 a, g dbSNP:141229326
737 737 -, g dbSNP:776959559
738 738 c, t dbSNP:34161743
739 739 a, g dbSNP:368339212
742 742 a, g dbSNP:375295397
748 748 a, g dbSNP:764422186
751 751 a, g dbSNP:760638672
753 753 a, t dbSNP:775668216
760 760 c, t dbSNP:568686293
767 767 -, gagt dbSNP:768961218
780 780 a, g dbSNP:772403818
782 782 -, aga dbSNP:747407591
792 792 c, t dbSNP:376834028
793 793 a, g dbSNP:545723392
800 800 c, t dbSNP:146059027
801 801 c, g dbSNP:139629845
803 803 a, g dbSNP:370461642
805 805 a, g dbSNP:377243932
807 807 c, g dbSNP:768389092
811 811 a, c dbSNP:746456274
813 813 a, c dbSNP:779628611
814 814 c, g, t dbSNP:372603248
816 816 c, t dbSNP:778879440
817 817 a, g dbSNP:139473535
821 821 c, t dbSNP:753669717
823 823 c, g, t dbSNP:756377863
831 831 a, g dbSNP:752656803
832 832 c, t dbSNP:767632630
846 846 a, g dbSNP:149303773
852 852 c, t dbSNP:774980216
868 868 a, g dbSNP:752954187
875 875 c, t dbSNP:150598676
878 878 c, g dbSNP:755079453
880 880 a, g dbSNP:751720819
889 889 c, g dbSNP:369446796
893 893 a, g dbSNP:138159825
901 901 c, t dbSNP:773380358
904 904 c, t dbSNP:202054823
908 908 a, t dbSNP:762142599
917 917 c, t dbSNP:775185492
926 926 a, g, t dbSNP:745338458
932 932 c, t dbSNP:773871551
933 933 a, g dbSNP:375116822
935 935 a, c, t dbSNP:777632204
938 938 c, t dbSNP:367668454
946 946 c, t dbSNP:747937878
948 948 g, t dbSNP:781436406
952 952 c, t dbSNP:41270857
963 963 a, g dbSNP:751634864
979 979 -, a dbSNP:751138627
981 981 a, g dbSNP:780283429
982 982 a, c dbSNP:758616441
986 986 a, g dbSNP:750927922
989 989 c, t dbSNP:2307424
990 990 a, g dbSNP:143067018
996 996 c, t dbSNP:754182730
997 997 a, g dbSNP:767105877
1004 1004 a, g, t dbSNP:754170136
1005 1005 c, t dbSNP:764443927
1007 1007 c, t dbSNP:761088863
1009 1009 c, t dbSNP:564859096
1026 1026 c, g dbSNP:766064438
1029 1029 c, t dbSNP:772286234
1060 1060 c, t dbSNP:762489220
1062 1062 a, g dbSNP:772619920
1063 1063 g, t dbSNP:769715201
1077 1077 c, t dbSNP:746125471
1084 1084 a, t dbSNP:761662278
1091 1091 a, c dbSNP:776774308
1106 1106 c, t dbSNP:544805520
1107 1107 a, g dbSNP:746849037
1109 1109 a, g dbSNP:780391681
1110 1110 c, t dbSNP:772210168
1116 1116 c, t dbSNP:745909079
1129 1129 a, c dbSNP:778869769
1139 1139 c, t dbSNP:149864108
1141 1141 a, g dbSNP:145025028
1142 1142 c, t dbSNP:559151462
1152 1152 c, t dbSNP:777631690
1155 1155 a, g dbSNP:754957464
1160 1160 c, g, t dbSNP:201028035
1161 1161 c, t dbSNP:762797428
1162 1162 a, g dbSNP:142330499
1167 1167 a, g dbSNP:765481537
1178 1178 a, g dbSNP:761756373
1181 1181 a, g dbSNP:776791009
1185 1185 g, t dbSNP:768982496
1187 1187 c, g dbSNP:761248912
1189 1189 c, t dbSNP:775926630
1196 1196 c, g dbSNP:772550648
1207 1207 -, a dbSNP:769443369
1213 1213 c, t dbSNP:746281035
1241 1241 a, c dbSNP:199534928
1248 1248 c, t dbSNP:769594436
1249 1249 a, g dbSNP:200523878
1257 1257 c, t dbSNP:148675838
1258 1258 a, g dbSNP:754515980
1263 1263 c, t dbSNP:143583938
1264 1264 a, g dbSNP:114879683
1265 1265 g, t dbSNP:760125469
1273 1273 a, t dbSNP:775065775
1276 1276 c, t dbSNP:200408085
1277 1277 a, g dbSNP:36017137
1280 1280 c, g dbSNP:776318584
1281 1281 c, t dbSNP:768226364
1283 1283 a, g dbSNP:373127924
1285 1285 c, t dbSNP:774991039
1286 1286 a, c dbSNP:150124500
1287 1287 a, c, g, t dbSNP:2307414
1301 1301 a, g dbSNP:745800174
1305 1305 c, t dbSNP:369817002
1306 1306 a, g dbSNP:376397342
1308 1308 a, g dbSNP:770736555
1315 1315 a, t dbSNP:139722132
1320 1320 a, g dbSNP:749076282
1325 1325 c, t dbSNP:79799851
1326 1326 a, g dbSNP:756304664
1339 1339 a, g dbSNP:752758736
1340 1340 c, g dbSNP:781417564
1341 1341 c, t dbSNP:373882046
1347 1347 -, cagggcc dbSNP:779493594
1350 1350 c, g dbSNP:752094371
1369 1369 c, t dbSNP:758748494
1370 1370 a, g dbSNP:200228217
1373 1373 g, t dbSNP:141332323
1379 1379 a, g dbSNP:141389397
1385 1385 a, c dbSNP:369311646
1390 1390 a, c, g, t dbSNP:771557332
1396 1396 a, g dbSNP:140549301
1399 1399 a, g dbSNP:774313084
1401 1401 g, t dbSNP:376510791
1402 1402 c, t dbSNP:147849659
1407 1407 g, t dbSNP:777436441
1414 1414 c, t dbSNP:769779489
1422 1422 a, t dbSNP:748367918
1434 1434 a, c dbSNP:781617937
1443 1443 -, c dbSNP:771091045
1445 1445 a, g dbSNP:755081784
1452 1452 a, g dbSNP:751722876
1457 1457 c, t dbSNP:780564353
1458 1458 a, g dbSNP:755279262
1460 1460 -, t dbSNP:749380602
1463 1463 a, g dbSNP:3813629
1465 1465 c, t dbSNP:537248708
1478 1478 a, c, t dbSNP:201243903
1479 1479 a, g dbSNP:34645321
1480 1480 a, c, g dbSNP:2307416
1486 1486 a, c dbSNP:752324753
1487 1487 -, a dbSNP:778081793
1494 1494 c, t dbSNP:767195966
1499 1499 g, t dbSNP:759006086
1501 1501 c, t dbSNP:773748252
1508 1508 a, g dbSNP:766275202
1517 1517 a, g dbSNP:368521829

Target ORF information:

RefSeq Version XM_011510237
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens nuclear receptor subfamily 1, group I, member 3 (NR1I3), transcript variant X3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011510237

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
ATGAGTCACA AGGTTCCCAC CCACTGGAGT CCCTCCCCGT GTGCCACCAA CCAGCACTTT 
TGTCATGCTG GGAAAACCTC CCACCCAGGC CTTTGCCCTG AGTCCAGGGT CTGTGCCCTA
ACCCCACAGT CACTGAGAGC AACTGGAGGC CACATAAAAC AGACATCTCT TGTTTTCCAG
ATACTACGGG TCATAATCCC TAACTCCAAT CACTGGCAAC TCCTGAGATC AGAGGAAAAC
CAGCAACAGC GTGGGAGTTT GGGGAGAGGC ATTCCATACC AGATTCTGTG GCCTGCAGGT
GACATGCTGC CTAAGAGAAG CAGGAGAACA GTCAGCAAAA GCATTGGTCC CACCTGCCCC
TTTGCTGGAA GCTGTGAAGT CAGCAAGACT CAGAGGCGCC ACTGCCCAGC CTGCAGGTTG
CAGAAGTGCT TAGATGCTGG CATGAGGAAA GACATGATAC TGTCGGCAGA AGCCCTGGCA
TTGCGGCGAG CAAAGCAGGC CCAGCGGCGG GCACAGCAAA CACCTGTGCA ACTGAGTAAG
GAGCAAGAAG AGCTGATCCG GACACTCCTG GGGGCCCACA CCCGCCACAT GGGCACCATG
TTTGAACAGT TTGTGCAGTT TAGGCCTCCA GCTCATCTGT TCATCCATCA CCAGCCCTTG
CCCACCCTGG CCCCTGTGCT GCCTCTGGTC ACACACTTCG CAGACATCAA CACTTTCATG
GTACTGCAAG TCATCAAGTT TACTAAGGAC CTGCCCGTCT TCCGTTCCCT GCCCATTGAA
GACCAGATCT CCCTTCTCAA GGGAGCAGCT GTGGAAATCT GTCACATCGT ACTCAATACC
ACTTTCTGTC TCCAAACACA AAACTTCCTC TGCGGGCCTC TTCGCTACAC AATTGAAGAT
GGAGCCCGTG CTCCCTATCT TACAGACCGA CCTGGAGTTA CCCAGAGAGA TGAGATTGAT
CAGCTGCAAG AGGAGATGGC ACTGACTCTG CAAAGCTACA TCAAGGGCCA GCAGCGAAGG
CCCCGGGATC GGTTTCTGTA TGCGAAGTTG CTAGGCCTGC TGGCTGAGCT CCGGAGCATT
AATGAGGCCT ACGGGTACCA AATCCAGCAC ATCCAGGGCC TGTCTGCCAT GATGCCGCTG
CTCCAGGAGA TCTGCAGCTG A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu34914
Accession Version XM_005245697.3 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1062bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector Document: User manual_GenEZ ORF Clone Products.pdf (pdf)
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags Document: MSDS_GenEZ ORF Clone Products.pdf (pdf)
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product nuclear receptor subfamily 1 group I member 3 isoform X4
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_004487.20) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 12, 2015 this sequence version replaced gi:578801885. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
ATGGCCAGTA GGGAAGATGA GCTGAGGAAC TGTGTGGTAT GTGGGGACCA AGCCACAGGC 
TACCACTTTA ATGCGCTGAC TTGTGAGGGC TGCAAGGGTT TCTTCAGGAG AACAGTCAGC
AAAAGCATTG GTCCCACCTG CCCCTTTGCT GGAAGCTGTG AAGTCAGCAA GACTCAGAGG
CGCCACTGCC CAGCCTGCAG GTTGCAGAAG TGCTTAGATG CTGGCATGAG GAAAGACATG
ATACTGTCGG CAGAAGCCCT GGCATTGCGG CGAGCAAAGC AGGCCCAGCG GCGGGCACAG
CAAACACCTG TGCAACTGAG TAAGGAGCAA GAAGAGCTGA TCCGGACACT CCTGGGGGCC
CACACCCGCC ACATGGGCAC CATGTTTGAA CAGTTTGTGC AGTTTAGGCC TCCAGCTCAT
CTGTTCATCC ATCACCAGCC CTTGCCCACC CTGGCCCCTG TGCTGCCTCT GGTCACACAC
TTCGCAGACA TCAACACTTT CATGGTACTG CAAGTCATCA AGTTTACTAA GGACCTGCCC
GTCTTCCGTT CCCTGCCCAT TGAAGACCAG ATCTCCCTTC TCAAGGGAGC AGCTGTGGAA
ATCTGTCACA TCGTACTCAA TACCACTTTC TGTCTCCAAA CACAAAACTT CCTCTGCGGG
CCTCTTCGCT ACACAATTGA AGATGGAGCC CGTGTGGGGT TCCAGGTAGA GTTTTTGGAG
TTGCTCTTTC ACTTCCATGG AACACTACGA AAACTGCAGC TCCAAGAGCC TGAGTATGTG
CTCTTGGCTG CCATGGCCCT CTTCTCTCCT GCTCCCTATC TTACAGACCG ACCTGGAGTT
ACCCAGAGAG ATGAGATTGA TCAGCTGCAA GAGGAGATGG CACTGACTCT GCAAAGCTAC
ATCAAGGGCC AGCAGCGAAG GCCCCGGGAT CGGTTTCTGT ATGCGAAGTT GCTAGGCCTG
CTGGCTGAGC TCCGGAGCAT TAATGAGGCC TACGGGTACC AAATCCAGCA CATCCAGGGC
CTGTCTGCCA TGATGCCGCT GCTCCAGGAG ATCTGCAGCT GA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqXP_005245754.1
CDS87..1148
Misc Feature(1)117..332(+)
Misc Feature(2)117..284(+)
Misc Feature(3)147..332(+)
Misc Feature(4)228..326(+)
Misc Feature(5)402..1139(+)
Misc Feature(6)564..1079(+)
Misc Feature(7)603..1139(+)
Misc Feature(8)807..1073(+)
Translation
Position Chain Variation Link
5 5 c, t dbSNP:758722723
7 7 c, t dbSNP:750479350
21 21 a, g dbSNP:765416900
22 22 c, g dbSNP:757636106
23 23 c, t dbSNP:754360419
27 27 a, g dbSNP:764563799
31 31 a, g dbSNP:376555075
35 35 a, t dbSNP:372090555
42 42 c, t dbSNP:181499203
44 44 a, g dbSNP:188975149
50 50 a, g, t dbSNP:769343586
68 68 a, c dbSNP:759962703
72 72 c, g dbSNP:376099705
74 74 a, g dbSNP:764847585
78 78 c, g, t dbSNP:776036693
83 83 c, t dbSNP:768587526
84 84 a, g dbSNP:2307415
89 89 a, g dbSNP:373168365
94 94 a, g dbSNP:775354866
101 101 a, c dbSNP:771986174
110 110 a, g dbSNP:745711502
113 113 -, g dbSNP:754115870
115 115 a, t dbSNP:779169935
129 129 a, g dbSNP:200774078
135 135 a, c dbSNP:749342923
160 160 a, c, t dbSNP:756548242
161 161 a, g dbSNP:140012276
171 171 c, g dbSNP:781707733
174 174 g, t dbSNP:755313912
176 176 c, t dbSNP:751908933
180 180 a, c dbSNP:764903201
194 194 -, gag dbSNP:764025470
195 195 a, c dbSNP:755509541
199 199 -, c dbSNP:760565010
200 200 a, c dbSNP:777971759
214 214 c, t dbSNP:747349033
220 220 a, c dbSNP:780293934
221 221 -, c dbSNP:775526201
221 221 c, t dbSNP:756865381
222 222 a, c dbSNP:753425575
228 228 c, g dbSNP:763894632
230 230 -, cc dbSNP:767358929
230 230 c, g dbSNP:544741783
231 231 c, t dbSNP:201089859
234 234 a, g dbSNP:752292550
235 235 c, t dbSNP:767517431
242 242 c, g dbSNP:759410250
243 243 g, t dbSNP:774131812
257 257 a, g dbSNP:766084148
262 262 a, t dbSNP:762865830
265 265 a, g dbSNP:142842008
266 266 g, t dbSNP:138077816
267 267 c, t dbSNP:748184864
268 268 a, g dbSNP:148277311
274 274 a, g, t dbSNP:747474209
275 275 a, c, t dbSNP:758672635
282 282 a, t dbSNP:565978374
283 283 g, t dbSNP:777533188
287 287 c, g dbSNP:755856811
299 299 a, c dbSNP:200078573
304 304 a, g dbSNP:112022118
312 312 a, g dbSNP:752198862
314 314 a, g dbSNP:548963536
319 319 -, aa dbSNP:759027156
330 330 c, t dbSNP:779436154
334 334 c, t dbSNP:373897043
335 335 a, g dbSNP:2307425
338 338 a, g dbSNP:781053597
344 344 c, g dbSNP:35205211
348 348 a, g dbSNP:751122638
355 355 a, g dbSNP:376162036
358 358 a, g dbSNP:531442743
366 366 a, c dbSNP:750159568
369 369 a, g dbSNP:563503102
374 374 a, g dbSNP:141229326
374 374 -, g dbSNP:776959559
375 375 c, t dbSNP:34161743
376 376 a, g dbSNP:368339212
379 379 a, g dbSNP:375295397
385 385 a, g dbSNP:764422186
388 388 a, g dbSNP:760638672
390 390 a, t dbSNP:775668216
397 397 c, t dbSNP:568686293
404 404 -, gagt dbSNP:768961218
417 417 a, g dbSNP:772403818
419 419 -, aga dbSNP:747407591
429 429 c, t dbSNP:376834028
430 430 a, g dbSNP:545723392
437 437 c, t dbSNP:146059027
438 438 c, g dbSNP:139629845
440 440 a, g dbSNP:370461642
442 442 a, g dbSNP:377243932
444 444 c, g dbSNP:768389092
448 448 a, c dbSNP:746456274
450 450 a, c dbSNP:779628611
451 451 c, g, t dbSNP:372603248
453 453 c, t dbSNP:778879440
454 454 a, g dbSNP:139473535
458 458 c, t dbSNP:753669717
460 460 c, g, t dbSNP:756377863
468 468 a, g dbSNP:752656803
469 469 c, t dbSNP:767632630
483 483 a, g dbSNP:149303773
489 489 c, t dbSNP:774980216
505 505 a, g dbSNP:752954187
512 512 c, t dbSNP:150598676
515 515 c, g dbSNP:755079453
517 517 a, g dbSNP:751720819
526 526 c, g dbSNP:369446796
530 530 a, g dbSNP:138159825
538 538 c, t dbSNP:773380358
541 541 c, t dbSNP:202054823
545 545 a, t dbSNP:762142599
554 554 c, t dbSNP:775185492
563 563 a, g, t dbSNP:745338458
569 569 c, t dbSNP:773871551
570 570 a, g dbSNP:375116822
572 572 a, c, t dbSNP:777632204
575 575 c, t dbSNP:367668454
583 583 c, t dbSNP:747937878
585 585 g, t dbSNP:781436406
589 589 c, t dbSNP:41270857
600 600 a, g dbSNP:751634864
616 616 -, a dbSNP:751138627
618 618 a, g dbSNP:780283429
619 619 a, c dbSNP:758616441
623 623 a, g dbSNP:750927922
626 626 c, t dbSNP:2307424
627 627 a, g dbSNP:143067018
633 633 c, t dbSNP:754182730
634 634 a, g dbSNP:767105877
641 641 a, g, t dbSNP:754170136
642 642 c, t dbSNP:764443927
644 644 c, t dbSNP:761088863
646 646 c, t dbSNP:564859096
663 663 c, g dbSNP:766064438
666 666 c, t dbSNP:772286234
697 697 c, t dbSNP:762489220
699 699 a, g dbSNP:772619920
700 700 g, t dbSNP:769715201
714 714 c, t dbSNP:746125471
721 721 a, t dbSNP:761662278
728 728 a, c dbSNP:776774308
743 743 c, t dbSNP:544805520
744 744 a, g dbSNP:746849037
746 746 a, g dbSNP:780391681
747 747 c, t dbSNP:772210168
753 753 c, t dbSNP:745909079
766 766 a, c dbSNP:778869769
776 776 c, t dbSNP:149864108
778 778 a, g dbSNP:145025028
779 779 c, t dbSNP:559151462
785 785 a, g dbSNP:774699125
787 787 g, t dbSNP:770895742
798 798 c, t dbSNP:146624074
799 799 c, t dbSNP:778217125
804 804 a, g dbSNP:756640389
808 808 -, t dbSNP:751049065
813 813 -, tttcacttc dbSNP:765857067
814 814 c, t dbSNP:398122411
822 822 c, t dbSNP:748454600
823 823 a, g dbSNP:201406656
828 828 a, g dbSNP:781415233
831 831 c, t dbSNP:755439721
834 834 a, c, g, t dbSNP:144211465
835 835 a, g dbSNP:753430504
862 862 a, g dbSNP:764070169
867 867 c, g dbSNP:760698101
879 879 a, g dbSNP:113800307
880 880 a, t dbSNP:775354782
881 881 a, g dbSNP:767209723
894 894 a, c dbSNP:1140627
895 895 c, t dbSNP:759426392
896 896 a, t dbSNP:66915105
897 897 a, g dbSNP:774408356
906 906 c, t dbSNP:777631690
909 909 a, g dbSNP:754957464
914 914 c, g, t dbSNP:201028035
915 915 c, t dbSNP:762797428
916 916 a, g dbSNP:142330499
921 921 a, g dbSNP:765481537
932 932 a, g dbSNP:761756373
935 935 a, g dbSNP:776791009
939 939 g, t dbSNP:768982496
941 941 c, g dbSNP:761248912
943 943 c, t dbSNP:775926630
950 950 c, g dbSNP:772550648
961 961 -, a dbSNP:769443369
967 967 c, t dbSNP:746281035
995 995 a, c dbSNP:199534928
1002 1002 c, t dbSNP:769594436
1003 1003 a, g dbSNP:200523878
1011 1011 c, t dbSNP:148675838
1012 1012 a, g dbSNP:754515980
1017 1017 c, t dbSNP:143583938
1018 1018 a, g dbSNP:114879683
1019 1019 g, t dbSNP:760125469
1027 1027 a, t dbSNP:775065775
1030 1030 c, t dbSNP:200408085
1031 1031 a, g dbSNP:36017137
1034 1034 c, g dbSNP:776318584
1035 1035 c, t dbSNP:768226364
1037 1037 a, g dbSNP:373127924
1039 1039 c, t dbSNP:774991039
1040 1040 a, c dbSNP:150124500
1041 1041 a, c, g, t dbSNP:2307414
1055 1055 a, g dbSNP:745800174
1059 1059 c, t dbSNP:369817002
1060 1060 a, g dbSNP:376397342
1062 1062 a, g dbSNP:770736555
1069 1069 a, t dbSNP:139722132
1074 1074 a, g dbSNP:749076282
1079 1079 c, t dbSNP:79799851
1080 1080 a, g dbSNP:756304664
1093 1093 a, g dbSNP:752758736
1094 1094 c, g dbSNP:781417564
1095 1095 c, t dbSNP:373882046
1101 1101 -, cagggcc dbSNP:779493594
1104 1104 c, g dbSNP:752094371
1123 1123 c, t dbSNP:758748494
1124 1124 a, g dbSNP:200228217
1127 1127 g, t dbSNP:141332323
1133 1133 a, g dbSNP:141389397
1139 1139 a, c dbSNP:369311646
1144 1144 a, c, g, t dbSNP:771557332
1150 1150 a, g dbSNP:140549301
1153 1153 a, g dbSNP:774313084
1155 1155 g, t dbSNP:376510791
1156 1156 c, t dbSNP:147849659
1161 1161 g, t dbSNP:777436441
1168 1168 c, t dbSNP:769779489
1176 1176 a, t dbSNP:748367918
1188 1188 a, c dbSNP:781617937
1197 1197 -, c dbSNP:771091045
1199 1199 a, g dbSNP:755081784
1206 1206 a, g dbSNP:751722876
1211 1211 c, t dbSNP:780564353
1212 1212 a, g dbSNP:755279262
1214 1214 -, t dbSNP:749380602
1217 1217 a, g dbSNP:3813629
1219 1219 c, t dbSNP:537248708
1232 1232 a, c, t dbSNP:201243903
1233 1233 a, g dbSNP:34645321
1234 1234 a, c, g dbSNP:2307416
1240 1240 a, c dbSNP:752324753
1241 1241 -, a dbSNP:778081793
1248 1248 c, t dbSNP:767195966
1253 1253 g, t dbSNP:759006086
1255 1255 c, t dbSNP:773748252
1262 1262 a, g dbSNP:766275202
1271 1271 a, g dbSNP:368521829

Target ORF information:

RefSeq Version XM_005245697
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens nuclear receptor subfamily 1, group I, member 3 (NR1I3), transcript variant X4, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_005245697

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
ATGGCCAGTA GGGAAGATGA GCTGAGGAAC TGTGTGGTAT GTGGGGACCA AGCCACAGGC 
TACCACTTTA ATGCGCTGAC TTGTGAGGGC TGCAAGGGTT TCTTCAGGAG AACAGTCAGC
AAAAGCATTG GTCCCACCTG CCCCTTTGCT GGAAGCTGTG AAGTCAGCAA GACTCAGAGG
CGCCACTGCC CAGCCTGCAG GTTGCAGAAG TGCTTAGATG CTGGCATGAG GAAAGACATG
ATACTGTCGG CAGAAGCCCT GGCATTGCGG CGAGCAAAGC AGGCCCAGCG GCGGGCACAG
CAAACACCTG TGCAACTGAG TAAGGAGCAA GAAGAGCTGA TCCGGACACT CCTGGGGGCC
CACACCCGCC ACATGGGCAC CATGTTTGAA CAGTTTGTGC AGTTTAGGCC TCCAGCTCAT
CTGTTCATCC ATCACCAGCC CTTGCCCACC CTGGCCCCTG TGCTGCCTCT GGTCACACAC
TTCGCAGACA TCAACACTTT CATGGTACTG CAAGTCATCA AGTTTACTAA GGACCTGCCC
GTCTTCCGTT CCCTGCCCAT TGAAGACCAG ATCTCCCTTC TCAAGGGAGC AGCTGTGGAA
ATCTGTCACA TCGTACTCAA TACCACTTTC TGTCTCCAAA CACAAAACTT CCTCTGCGGG
CCTCTTCGCT ACACAATTGA AGATGGAGCC CGTGTGGGGT TCCAGGTAGA GTTTTTGGAG
TTGCTCTTTC ACTTCCATGG AACACTACGA AAACTGCAGC TCCAAGAGCC TGAGTATGTG
CTCTTGGCTG CCATGGCCCT CTTCTCTCCT GCTCCCTATC TTACAGACCG ACCTGGAGTT
ACCCAGAGAG ATGAGATTGA TCAGCTGCAA GAGGAGATGG CACTGACTCT GCAAAGCTAC
ATCAAGGGCC AGCAGCGAAG GCCCCGGGAT CGGTTTCTGT ATGCGAAGTT GCTAGGCCTG
CTGGCTGAGC TCCGGAGCAT TAATGAGGCC TACGGGTACC AAATCCAGCA CATCCAGGGC
CTGTCTGCCA TGATGCCGCT GCTCCAGGAG ATCTGCAGCT GA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu10438
Accession Version NM_001077480.2 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1059bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector Document: User manual_GenEZ ORF Clone Products.pdf (pdf)
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags Document: MSDS_GenEZ ORF Clone Products.pdf (pdf)
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product nuclear receptor subfamily 1 group I member 3 isoform 2
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from CB124867.1, BC069626.1, AL590714.27 and AA918394.1. On Jan 15, 2011 this sequence version replaced gi:117938751. Summary: This gene encodes a member of the nuclear receptor superfamily, and is a key regulator of xenobiotic and endobiotic metabolism. The protein binds to DNA as a monomer or a heterodimer with the retinoid X receptor and regulates the transcription of target genes involved in drug metabolism and bilirubin clearance, such as cytochrome P450 family members. Unlike most nuclear receptors, this transcriptional regulator is constitutively active in the absence of ligand but is regulated by both agonists and inverse agonists. Ligand binding results in translocation of this protein to the nucleus, where it activates or represses target gene transcription. These ligands include bilirubin, a variety of foreign compounds, steroid hormones, and prescription drugs. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]. Transcript Variant: This variant (2) uses an alternate splice site in the 3' coding region, compared to variant 1. The resulting protein (isoform 2) is shorter than isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC069626.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1968968, SAMEA1970526 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: full length.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
ATGGCCAGTA GGGAAGATGA GCTGAGGAAC TGTGTGGTAT GTGGGGACCA AGCCACAGGC 
TACCACTTTA ATGCGCTGAC TTGTGAGGGC TGCAAGGGTT TCTTCAGGAG AACAGTCAGC
AAAAGCATTG GTCCCACCTG CCCCTTTGCT GGAAGCTGTG AAGTCAGCAA GACTCAGAGG
CGCCACTGCC CAGCCTGCAG GTTGCAGAAG TGCTTAGATG CTGGCATGAG GAAAGACATG
ATACTGTCGG CAGAAGCCCT GGCATTGCGG CGAGCAAAGC AGGCCCAGCG GCGGGCACAG
CAAACACCTG TGCAACTGAG TAAGGAGCAA GAAGAGCTGA TCCGGACACT CCTGGGGGCC
CACACCCGCC ACATGGGCAC CATGTTTGAA CAGTTTGTGC AGTTTAGGCC TCCAGCTCAT
CTGTTCATCC ATCACCAGCC CTTGCCCACC CTGGCCCCTG TGCTGCCTCT GGTCACACAC
TTCGCAGACA TCAACACTTT CATGGTACTG CAAGTCATCA AGTTTACTAA GGACCTGCCC
GTCTTCCGTT CCCTGCCCAT TGAAGACCAG ATCTCCCTTC TCAAGGGAGC AGCTGTGGAA
ATCTGTCACA TCGTACTCAA TACCACTTTC TGTCTCCAAA CACAAAACTT CCTCTGCGGG
CCTCTTCGCT ACACAATTGA AGATGGAGCC CGTGTATCTC CCACAGTGGG GTTCCAGGTA
GAGTTTTTGG AGTTGCTCTT TCACTTCCAT GGAACACTAC GAAAACTGCA GCTCCAAGAG
CCTGAGTATG TGCTCTTGGC TGCCATGGCC CTCTTCTCTC CTGACCGACC TGGAGTTACC
CAGAGAGATG AGATTGATCA GCTGCAAGAG GAGATGGCAC TGACTCTGCA AAGCTACATC
AAGGGCCAGC AGCGAAGGCC CCGGGATCGG TTTCTGTATG CGAAGTTGCT AGGCCTGCTG
GCTGAGCTCC GGAGCATTAA TGAGGCCTAC GGGTACCAAA TCCAGCACAT CCAGGGCCTG
TCTGCCATGA TGCCGCTGCT CCAGGAGATC TGCAGCTGA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_001070948.1
CDS204..1262
Misc Feature(1)52..52(+)
Misc Feature(2)159..161(+)
Misc Feature(3)234..449(+)
Misc Feature(4)234..401(+)
Misc Feature(5)264..449(+)
Misc Feature(6)315..317(+)
Misc Feature(7)345..443(+)
Misc Feature(8)519..1253(+)
Misc Feature(9)681..1193(+)
Misc Feature(10)720..1253(+)
Misc Feature(11)936..1187(+)
Exon (1)1..170
Gene:NR1I3
Gene Synonym:
Exon (2)171..310
Gene:NR1I3
Gene Synonym:
Exon (3)311..441
Gene:NR1I3
Gene Synonym:
Exon (4)442..611
Gene:NR1I3
Gene Synonym:
Exon (5)612..751
Gene:NR1I3
Gene Synonym:
Exon (6)752..897
Gene:NR1I3
Gene Synonym:
Exon (7)898..1026
Gene:NR1I3
Gene Synonym:
Exon (8)1027..1132
Gene:NR1I3
Gene Synonym:
Exon (9)1133..1393
Gene:NR1I3
Gene Synonym:
Translation
Position Chain Variation Link
38 38 c, t dbSNP:762782589
65 65 a, c dbSNP:555012220
66 66 a, g dbSNP:538519022
98 98 a, g dbSNP:568943207
110 110 c, g dbSNP:746849019
114 114 a, t dbSNP:780391609
122 122 c, t dbSNP:758722723
124 124 c, t dbSNP:750479350
138 138 a, g dbSNP:765416900
139 139 c, g dbSNP:757636106
140 140 c, t dbSNP:754360419
144 144 a, g dbSNP:764563799
148 148 a, g dbSNP:376555075
152 152 a, t dbSNP:372090555
159 159 c, t dbSNP:181499203
161 161 a, g dbSNP:188975149
167 167 a, g, t dbSNP:769343586
185 185 a, c dbSNP:759962703
189 189 c, g dbSNP:376099705
191 191 a, g dbSNP:764847585
195 195 c, g, t dbSNP:776036693
200 200 c, t dbSNP:768587526
201 201 a, g dbSNP:2307415
206 206 a, g dbSNP:373168365
211 211 a, g dbSNP:775354866
218 218 a, c dbSNP:771986174
227 227 a, g dbSNP:745711502
230 230 -, g dbSNP:754115870
232 232 a, t dbSNP:779169935
246 246 a, g dbSNP:200774078
252 252 a, c dbSNP:749342923
277 277 a, c, t dbSNP:756548242
278 278 a, g dbSNP:140012276
288 288 c, g dbSNP:781707733
291 291 g, t dbSNP:755313912
293 293 c, t dbSNP:751908933
297 297 a, c dbSNP:764903201
311 311 -, gag dbSNP:764025470
312 312 a, c dbSNP:755509541
316 316 -, c dbSNP:760565010
317 317 a, c dbSNP:777971759
331 331 c, t dbSNP:747349033
337 337 a, c dbSNP:780293934
338 338 -, c dbSNP:775526201
338 338 c, t dbSNP:756865381
339 339 a, c dbSNP:753425575
345 345 c, g dbSNP:763894632
347 347 -, cc dbSNP:767358929
347 347 c, g dbSNP:544741783
348 348 c, t dbSNP:201089859
351 351 a, g dbSNP:752292550
352 352 c, t dbSNP:767517431
359 359 c, g dbSNP:759410250
360 360 g, t dbSNP:774131812
374 374 a, g dbSNP:766084148
379 379 a, t dbSNP:762865830
382 382 a, g dbSNP:142842008
383 383 g, t dbSNP:138077816
384 384 c, t dbSNP:748184864
385 385 a, g dbSNP:148277311
391 391 a, g, t dbSNP:747474209
392 392 a, c, t dbSNP:758672635
399 399 a, t dbSNP:565978374
400 400 g, t dbSNP:777533188
404 404 c, g dbSNP:755856811
416 416 a, c dbSNP:200078573
421 421 a, g dbSNP:112022118
429 429 a, g dbSNP:752198862
431 431 a, g dbSNP:548963536
436 436 -, aa dbSNP:759027156
447 447 c, t dbSNP:779436154
451 451 c, t dbSNP:373897043
452 452 a, g dbSNP:2307425
455 455 a, g dbSNP:781053597
461 461 c, g dbSNP:35205211
465 465 a, g dbSNP:751122638
472 472 a, g dbSNP:376162036
475 475 a, g dbSNP:531442743
483 483 a, c dbSNP:750159568
486 486 a, g dbSNP:563503102
491 491 a, g dbSNP:141229326
491 491 -, g dbSNP:776959559
492 492 c, t dbSNP:34161743
493 493 a, g dbSNP:368339212
496 496 a, g dbSNP:375295397
502 502 a, g dbSNP:764422186
505 505 a, g dbSNP:760638672
507 507 a, t dbSNP:775668216
514 514 c, t dbSNP:568686293
521 521 -, gagt dbSNP:768961218
534 534 a, g dbSNP:772403818
536 536 -, aga dbSNP:747407591
546 546 c, t dbSNP:376834028
547 547 a, g dbSNP:545723392
554 554 c, t dbSNP:146059027
555 555 c, g dbSNP:139629845
557 557 a, g dbSNP:370461642
559 559 a, g dbSNP:377243932
561 561 c, g dbSNP:768389092
565 565 a, c dbSNP:746456274
567 567 a, c dbSNP:779628611
568 568 c, g, t dbSNP:372603248
570 570 c, t dbSNP:778879440
571 571 a, g dbSNP:139473535
575 575 c, t dbSNP:753669717
577 577 c, g, t dbSNP:756377863
585 585 a, g dbSNP:752656803
586 586 c, t dbSNP:767632630
600 600 a, g dbSNP:149303773
606 606 c, t dbSNP:774980216
622 622 a, g dbSNP:752954187
629 629 c, t dbSNP:150598676
632 632 c, g dbSNP:755079453
634 634 a, g dbSNP:751720819
643 643 c, g dbSNP:369446796
647 647 a, g dbSNP:138159825
655 655 c, t dbSNP:773380358
658 658 c, t dbSNP:202054823
662 662 a, t dbSNP:762142599
671 671 c, t dbSNP:775185492
680 680 a, g, t dbSNP:745338458
686 686 c, t dbSNP:773871551
687 687 a, g dbSNP:375116822
689 689 a, c, t dbSNP:777632204
692 692 c, t dbSNP:367668454
700 700 c, t dbSNP:747937878
702 702 g, t dbSNP:781436406
706 706 c, t dbSNP:41270857
717 717 a, g dbSNP:751634864
733 733 -, a dbSNP:751138627
735 735 a, g dbSNP:780283429
736 736 a, c dbSNP:758616441
740 740 a, g dbSNP:750927922
743 743 c, t dbSNP:2307424
744 744 a, g dbSNP:143067018
750 750 c, t dbSNP:754182730
751 751 a, g dbSNP:767105877
758 758 a, g, t dbSNP:754170136
759 759 c, t dbSNP:764443927
761 761 c, t dbSNP:761088863
763 763 c, t dbSNP:564859096
780 780 c, g dbSNP:766064438
783 783 c, t dbSNP:772286234
814 814 c, t dbSNP:762489220
816 816 a, g dbSNP:772619920
817 817 g, t dbSNP:769715201
831 831 c, t dbSNP:746125471
838 838 a, t dbSNP:761662278
845 845 a, c dbSNP:776774308
860 860 c, t dbSNP:544805520
861 861 a, g dbSNP:746849037
863 863 a, g dbSNP:780391681
864 864 c, t dbSNP:772210168
870 870 c, t dbSNP:745909079
883 883 a, c dbSNP:778869769
893 893 c, t dbSNP:149864108
895 895 a, g dbSNP:145025028
896 896 c, t dbSNP:559151462
914 914 a, g dbSNP:774699125
916 916 g, t dbSNP:770895742
927 927 c, t dbSNP:146624074
928 928 c, t dbSNP:778217125
933 933 a, g dbSNP:756640389
937 937 -, t dbSNP:751049065
942 942 -, tttcacttc dbSNP:765857067
943 943 c, t dbSNP:398122411
951 951 c, t dbSNP:748454600
952 952 a, g dbSNP:201406656
957 957 a, g dbSNP:781415233
960 960 c, t dbSNP:755439721
963 963 a, c, g, t dbSNP:144211465
964 964 a, g dbSNP:753430504
991 991 a, g dbSNP:764070169
996 996 c, g dbSNP:760698101
1008 1008 a, g dbSNP:113800307
1009 1009 a, t dbSNP:775354782
1010 1010 a, g dbSNP:767209723
1023 1023 a, c dbSNP:1140627
1024 1024 c, t dbSNP:759426392
1025 1025 a, t dbSNP:66915105
1026 1026 a, g dbSNP:774408356
1028 1028 c, g, t dbSNP:201028035
1029 1029 c, t dbSNP:762797428
1030 1030 a, g dbSNP:142330499
1035 1035 a, g dbSNP:765481537
1046 1046 a, g dbSNP:761756373
1049 1049 a, g dbSNP:776791009
1053 1053 g, t dbSNP:768982496
1055 1055 c, g dbSNP:761248912
1057 1057 c, t dbSNP:775926630
1064 1064 c, g dbSNP:772550648
1075 1075 -, a dbSNP:769443369
1081 1081 c, t dbSNP:746281035
1109 1109 a, c dbSNP:199534928
1116 1116 c, t dbSNP:769594436
1117 1117 a, g dbSNP:200523878
1125 1125 c, t dbSNP:148675838
1126 1126 a, g dbSNP:754515980
1131 1131 c, t dbSNP:143583938
1132 1132 a, g dbSNP:114879683
1133 1133 g, t dbSNP:760125469
1141 1141 a, t dbSNP:775065775
1144 1144 c, t dbSNP:200408085
1145 1145 a, g dbSNP:36017137
1148 1148 c, g dbSNP:776318584
1149 1149 c, t dbSNP:768226364
1151 1151 a, g dbSNP:373127924
1153 1153 c, t dbSNP:774991039
1154 1154 a, c dbSNP:150124500
1155 1155 a, c, g, t dbSNP:2307414
1169 1169 a, g dbSNP:745800174
1173 1173 c, t dbSNP:369817002
1174 1174 a, g dbSNP:376397342
1176 1176 a, g dbSNP:770736555
1183 1183 a, t dbSNP:139722132
1188 1188 a, g dbSNP:749076282
1193 1193 c, t dbSNP:79799851
1194 1194 a, g dbSNP:756304664
1207 1207 a, g dbSNP:752758736
1208 1208 c, g dbSNP:781417564
1209 1209 c, t dbSNP:373882046
1215 1215 -, cagggcc dbSNP:779493594
1218 1218 c, g dbSNP:752094371
1237 1237 c, t dbSNP:758748494
1238 1238 a, g dbSNP:200228217
1241 1241 g, t dbSNP:141332323
1247 1247 a, g dbSNP:141389397
1253 1253 a, c dbSNP:369311646
1258 1258 a, c, g, t dbSNP:771557332
1264 1264 a, g dbSNP:140549301
1267 1267 a, g dbSNP:774313084
1269 1269 g, t dbSNP:376510791
1270 1270 c, t dbSNP:147849659
1275 1275 g, t dbSNP:777436441
1282 1282 c, t dbSNP:769779489
1290 1290 a, t dbSNP:748367918
1302 1302 a, c dbSNP:781617937
1311 1311 -, c dbSNP:771091045
1313 1313 a, g dbSNP:755081784
1320 1320 a, g dbSNP:751722876
1325 1325 c, t dbSNP:780564353
1326 1326 a, g dbSNP:755279262
1328 1328 -, t dbSNP:749380602
1331 1331 a, g dbSNP:3813629
1333 1333 c, t dbSNP:537248708
1346 1346 a, c, t dbSNP:201243903
1347 1347 a, g dbSNP:34645321
1348 1348 a, c, g dbSNP:2307416
1354 1354 a, c dbSNP:752324753
1355 1355 -, a dbSNP:778081793
1362 1362 c, t dbSNP:767195966
1367 1367 g, t dbSNP:759006086
1369 1369 c, t dbSNP:773748252
1376 1376 a, g dbSNP:766275202
1385 1385 a, g dbSNP:368521829

Target ORF information:

RefSeq Version NM_001077480
Organism Homo sapiens (human)
Definition Homo sapiens nuclear receptor subfamily 1, group I, member 3 (NR1I3), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001077480

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
ATGGCCAGTA GGGAAGATGA GCTGAGGAAC TGTGTGGTAT GTGGGGACCA AGCCACAGGC 
TACCACTTTA ATGCGCTGAC TTGTGAGGGC TGCAAGGGTT TCTTCAGGAG AACAGTCAGC
AAAAGCATTG GTCCCACCTG CCCCTTTGCT GGAAGCTGTG AAGTCAGCAA GACTCAGAGG
CGCCACTGCC CAGCCTGCAG GTTGCAGAAG TGCTTAGATG CTGGCATGAG GAAAGACATG
ATACTGTCGG CAGAAGCCCT GGCATTGCGG CGAGCAAAGC AGGCCCAGCG GCGGGCACAG
CAAACACCTG TGCAACTGAG TAAGGAGCAA GAAGAGCTGA TCCGGACACT CCTGGGGGCC
CACACCCGCC ACATGGGCAC CATGTTTGAA CAGTTTGTGC AGTTTAGGCC TCCAGCTCAT
CTGTTCATCC ATCACCAGCC CTTGCCCACC CTGGCCCCTG TGCTGCCTCT GGTCACACAC
TTCGCAGACA TCAACACTTT CATGGTACTG CAAGTCATCA AGTTTACTAA GGACCTGCCC
GTCTTCCGTT CCCTGCCCAT TGAAGACCAG ATCTCCCTTC TCAAGGGAGC AGCTGTGGAA
ATCTGTCACA TCGTACTCAA TACCACTTTC TGTCTCCAAA CACAAAACTT CCTCTGCGGG
CCTCTTCGCT ACACAATTGA AGATGGAGCC CGTGTATCTC CCACAGTGGG GTTCCAGGTA
GAGTTTTTGG AGTTGCTCTT TCACTTCCAT GGAACACTAC GAAAACTGCA GCTCCAAGAG
CCTGAGTATG TGCTCTTGGC TGCCATGGCC CTCTTCTCTC CTGACCGACC TGGAGTTACC
CAGAGAGATG AGATTGATCA GCTGCAAGAG GAGATGGCAC TGACTCTGCA AAGCTACATC
AAGGGCCAGC AGCGAAGGCC CCGGGATCGG TTTCTGTATG CGAAGTTGCT AGGCCTGCTG
GCTGAGCTCC GGAGCATTAA TGAGGCCTAC GGGTACCAAA TCCAGCACAT CCAGGGCCTG
TCTGCCATGA TGCCGCTGCT CCAGGAGATC TGCAGCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu12022
Accession Version NM_001077481.2 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 945bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector Document: User manual_GenEZ ORF Clone Products.pdf (pdf)
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags Document: MSDS_GenEZ ORF Clone Products.pdf (pdf)
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product nuclear receptor subfamily 1 group I member 3 isoform 4
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from CB124867.1, BC121120.1, AL590714.27 and AA918394.1. On Jan 15, 2011 this sequence version replaced gi:117938753. Summary: This gene encodes a member of the nuclear receptor superfamily, and is a key regulator of xenobiotic and endobiotic metabolism. The protein binds to DNA as a monomer or a heterodimer with the retinoid X receptor and regulates the transcription of target genes involved in drug metabolism and bilirubin clearance, such as cytochrome P450 family members. Unlike most nuclear receptors, this transcriptional regulator is constitutively active in the absence of ligand but is regulated by both agonists and inverse agonists. Ligand binding results in translocation of this protein to the nucleus, where it activates or represses target gene transcription. These ligands include bilirubin, a variety of foreign compounds, steroid hormones, and prescription drugs. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]. Transcript Variant: This variant (4) lacks an alternate in-frame exon in the 3' coding region, compared to variant 1. The resulting protein (isoform 4) is shorter than isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC121120.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1968968, SAMEA1970526 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: full length.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
ATGGCCAGTA GGGAAGATGA GCTGAGGAAC TGTGTGGTAT GTGGGGACCA AGCCACAGGC 
TACCACTTTA ATGCGCTGAC TTGTGAGGGC TGCAAGGGTT TCTTCAGGAG AACAGTCAGC
AAAAGCATTG GTCCCACCTG CCCCTTTGCT GGAAGCTGTG AAGTCAGCAA GACTCAGAGG
CGCCACTGCC CAGCCTGCAG GTTGCAGAAG TGCTTAGATG CTGGCATGAG GAAAGACATG
ATACTGTCGG CAGAAGCCCT GGCATTGCGG CGAGCAAAGC AGGCCCAGCG GCGGGCACAG
CAAACACCTG TGCAACTGAG TAAGGAGCAA GAAGAGCTGA TCCGGACACT CCTGGGGGCC
CACACCCGCC ACATGGGCAC CATGTTTGAA CAGTTTGTGC AGTTTAGGCC TCCAGCTCAT
CTGTTCATCC ATCACCAGCC CTTGCCCACC CTGGCCCCTG TGCTGCCTCT GGTCACACAC
TTCGCAGACA TCAACACTTT CATGGTACTG CAAGTCATCA AGTTTACTAA GGACCTGCCC
GTCTTCCGTT CCCTGCCCAT TGAAGACCAG ATCTCCCTTC TCAAGGGAGC AGCTGTGGAA
ATCTGTCACA TCGTACTCAA TACCACTTTC TGTCTCCAAA CACAAAACTT CCTCTGCGGG
CCTCTTCGCT ACACAATTGA AGATGGAGCC CGTGCTCCCT ATCTTACAGA CCGACCTGGA
GTTACCCAGA GAGATGAGAT TGATCAGCTG CAAGAGGAGA TGGCACTGAC TCTGCAAAGC
TACATCAAGG GCCAGCAGCG AAGGCCCCGG GATCGGTTTC TGTATGCGAA GTTGCTAGGC
CTGCTGGCTG AGCTCCGGAG CATTAATGAG GCCTACGGGT ACCAAATCCA GCACATCCAG
GGCCTGTCTG CCATGATGCC GCTGCTCCAG GAGATCTGCA GCTGA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_001070949.1
CDS204..1148
Misc Feature(1)52..52(+)
Misc Feature(2)159..161(+)
Misc Feature(3)234..449(+)
Misc Feature(4)234..401(+)
Misc Feature(5)264..449(+)
Misc Feature(6)345..443(+)
Misc Feature(7)519..1139(+)
Misc Feature(8)684..905(+)
Misc Feature(9)711..788(+)
Exon (1)1..170
Gene:NR1I3
Gene Synonym:
Exon (2)171..310
Gene:NR1I3
Gene Synonym:
Exon (3)311..441
Gene:NR1I3
Gene Synonym:
Exon (4)442..611
Gene:NR1I3
Gene Synonym:
Exon (5)612..751
Gene:NR1I3
Gene Synonym:
Exon (6)752..897
Gene:NR1I3
Gene Synonym:
Exon (7)898..1018
Gene:NR1I3
Gene Synonym:
Exon (8)1019..1279
Gene:NR1I3
Gene Synonym:
Translation
Position Chain Variation Link
38 38 c, t dbSNP:762782589
65 65 a, c dbSNP:555012220
66 66 a, g dbSNP:538519022
98 98 a, g dbSNP:568943207
110 110 c, g dbSNP:746849019
114 114 a, t dbSNP:780391609
122 122 c, t dbSNP:758722723
124 124 c, t dbSNP:750479350
138 138 a, g dbSNP:765416900
139 139 c, g dbSNP:757636106
140 140 c, t dbSNP:754360419
144 144 a, g dbSNP:764563799
148 148 a, g dbSNP:376555075
152 152 a, t dbSNP:372090555
159 159 c, t dbSNP:181499203
161 161 a, g dbSNP:188975149
167 167 a, g, t dbSNP:769343586
185 185 a, c dbSNP:759962703
189 189 c, g dbSNP:376099705
191 191 a, g dbSNP:764847585
195 195 c, g, t dbSNP:776036693
200 200 c, t dbSNP:768587526
201 201 a, g dbSNP:2307415
206 206 a, g dbSNP:373168365
211 211 a, g dbSNP:775354866
218 218 a, c dbSNP:771986174
227 227 a, g dbSNP:745711502
230 230 -, g dbSNP:754115870
232 232 a, t dbSNP:779169935
246 246 a, g dbSNP:200774078
252 252 a, c dbSNP:749342923
277 277 a, c, t dbSNP:756548242
278 278 a, g dbSNP:140012276
288 288 c, g dbSNP:781707733
291 291 g, t dbSNP:755313912
293 293 c, t dbSNP:751908933
297 297 a, c dbSNP:764903201
311 311 -, gag dbSNP:764025470
312 312 a, c dbSNP:755509541
316 316 -, c dbSNP:760565010
317 317 a, c dbSNP:777971759
331 331 c, t dbSNP:747349033
337 337 a, c dbSNP:780293934
338 338 -, c dbSNP:775526201
338 338 c, t dbSNP:756865381
339 339 a, c dbSNP:753425575
345 345 c, g dbSNP:763894632
347 347 -, cc dbSNP:767358929
347 347 c, g dbSNP:544741783
348 348 c, t dbSNP:201089859
351 351 a, g dbSNP:752292550
352 352 c, t dbSNP:767517431
359 359 c, g dbSNP:759410250
360 360 g, t dbSNP:774131812
374 374 a, g dbSNP:766084148
379 379 a, t dbSNP:762865830
382 382 a, g dbSNP:142842008
383 383 g, t dbSNP:138077816
384 384 c, t dbSNP:748184864
385 385 a, g dbSNP:148277311
391 391 a, g, t dbSNP:747474209
392 392 a, c, t dbSNP:758672635
399 399 a, t dbSNP:565978374
400 400 g, t dbSNP:777533188
404 404 c, g dbSNP:755856811
416 416 a, c dbSNP:200078573
421 421 a, g dbSNP:112022118
429 429 a, g dbSNP:752198862
431 431 a, g dbSNP:548963536
436 436 -, aa dbSNP:759027156
447 447 c, t dbSNP:779436154
451 451 c, t dbSNP:373897043
452 452 a, g dbSNP:2307425
455 455 a, g dbSNP:781053597
461 461 c, g dbSNP:35205211
465 465 a, g dbSNP:751122638
472 472 a, g dbSNP:376162036
475 475 a, g dbSNP:531442743
483 483 a, c dbSNP:750159568
486 486 a, g dbSNP:563503102
491 491 a, g dbSNP:141229326
491 491 -, g dbSNP:776959559
492 492 c, t dbSNP:34161743
493 493 a, g dbSNP:368339212
496 496 a, g dbSNP:375295397
502 502 a, g dbSNP:764422186
505 505 a, g dbSNP:760638672
507 507 a, t dbSNP:775668216
514 514 c, t dbSNP:568686293
521 521 -, gagt dbSNP:768961218
534 534 a, g dbSNP:772403818
536 536 -, aga dbSNP:747407591
546 546 c, t dbSNP:376834028
547 547 a, g dbSNP:545723392
554 554 c, t dbSNP:146059027
555 555 c, g dbSNP:139629845
557 557 a, g dbSNP:370461642
559 559 a, g dbSNP:377243932
561 561 c, g dbSNP:768389092
565 565 a, c dbSNP:746456274
567 567 a, c dbSNP:779628611
568 568 c, g, t dbSNP:372603248
570 570 c, t dbSNP:778879440
571 571 a, g dbSNP:139473535
575 575 c, t dbSNP:753669717
577 577 c, g, t dbSNP:756377863
585 585 a, g dbSNP:752656803
586 586 c, t dbSNP:767632630
600 600 a, g dbSNP:149303773
606 606 c, t dbSNP:774980216
622 622 a, g dbSNP:752954187
629 629 c, t dbSNP:150598676
632 632 c, g dbSNP:755079453
634 634 a, g dbSNP:751720819
643 643 c, g dbSNP:369446796
647 647 a, g dbSNP:138159825
655 655 c, t dbSNP:773380358
658 658 c, t dbSNP:202054823
662 662 a, t dbSNP:762142599
671 671 c, t dbSNP:775185492
680 680 a, g, t dbSNP:745338458
686 686 c, t dbSNP:773871551
687 687 a, g dbSNP:375116822
689 689 a, c, t dbSNP:777632204
692 692 c, t dbSNP:367668454
700 700 c, t dbSNP:747937878
702 702 g, t dbSNP:781436406
706 706 c, t dbSNP:41270857
717 717 a, g dbSNP:751634864
733 733 -, a dbSNP:751138627
735 735 a, g dbSNP:780283429
736 736 a, c dbSNP:758616441
740 740 a, g dbSNP:750927922
743 743 c, t dbSNP:2307424
744 744 a, g dbSNP:143067018
750 750 c, t dbSNP:754182730
751 751 a, g dbSNP:767105877
758 758 a, g, t dbSNP:754170136
759 759 c, t dbSNP:764443927
761 761 c, t dbSNP:761088863
763 763 c, t dbSNP:564859096
780 780 c, g dbSNP:766064438
783 783 c, t dbSNP:772286234
814 814 c, t dbSNP:762489220
816 816 a, g dbSNP:772619920
817 817 g, t dbSNP:769715201
831 831 c, t dbSNP:746125471
838 838 a, t dbSNP:761662278
845 845 a, c dbSNP:776774308
860 860 c, t dbSNP:544805520
861 861 a, g dbSNP:746849037
863 863 a, g dbSNP:780391681
864 864 c, t dbSNP:772210168
870 870 c, t dbSNP:745909079
883 883 a, c dbSNP:778869769
893 893 c, t dbSNP:149864108
895 895 a, g dbSNP:145025028
896 896 c, t dbSNP:559151462
906 906 c, t dbSNP:777631690
909 909 a, g dbSNP:754957464
914 914 c, g, t dbSNP:201028035
915 915 c, t dbSNP:762797428
916 916 a, g dbSNP:142330499
921 921 a, g dbSNP:765481537
932 932 a, g dbSNP:761756373
935 935 a, g dbSNP:776791009
939 939 g, t dbSNP:768982496
941 941 c, g dbSNP:761248912
943 943 c, t dbSNP:775926630
950 950 c, g dbSNP:772550648
961 961 -, a dbSNP:769443369
967 967 c, t dbSNP:746281035
995 995 a, c dbSNP:199534928
1002 1002 c, t dbSNP:769594436
1003 1003 a, g dbSNP:200523878
1011 1011 c, t dbSNP:148675838
1012 1012 a, g dbSNP:754515980
1017 1017 c, t dbSNP:143583938
1018 1018 a, g dbSNP:114879683
1019 1019 g, t dbSNP:760125469
1027 1027 a, t dbSNP:775065775
1030 1030 c, t dbSNP:200408085
1031 1031 a, g dbSNP:36017137
1034 1034 c, g dbSNP:776318584
1035 1035 c, t dbSNP:768226364
1037 1037 a, g dbSNP:373127924
1039 1039 c, t dbSNP:774991039
1040 1040 a, c dbSNP:150124500
1041 1041 a, c, g, t dbSNP:2307414
1055 1055 a, g dbSNP:745800174
1059 1059 c, t dbSNP:369817002
1060 1060 a, g dbSNP:376397342
1062 1062 a, g dbSNP:770736555
1069 1069 a, t dbSNP:139722132
1074 1074 a, g dbSNP:749076282
1079 1079 c, t dbSNP:79799851
1080 1080 a, g dbSNP:756304664
1093 1093 a, g dbSNP:752758736
1094 1094 c, g dbSNP:781417564
1095 1095 c, t dbSNP:373882046
1101 1101 -, cagggcc dbSNP:779493594
1104 1104 c, g dbSNP:752094371
1123 1123 c, t dbSNP:758748494
1124 1124 a, g dbSNP:200228217
1127 1127 g, t dbSNP:141332323
1133 1133 a, g dbSNP:141389397
1139 1139 a, c dbSNP:369311646
1144 1144 a, c, g, t dbSNP:771557332
1150 1150 a, g dbSNP:140549301
1153 1153 a, g dbSNP:774313084
1155 1155 g, t dbSNP:376510791
1156 1156 c, t dbSNP:147849659
1161 1161 g, t dbSNP:777436441
1168 1168 c, t dbSNP:769779489
1176 1176 a, t dbSNP:748367918
1188 1188 a, c dbSNP:781617937
1197 1197 -, c dbSNP:771091045
1199 1199 a, g dbSNP:755081784
1206 1206 a, g dbSNP:751722876
1211 1211 c, t dbSNP:780564353
1212 1212 a, g dbSNP:755279262
1214 1214 -, t dbSNP:749380602
1217 1217 a, g dbSNP:3813629
1219 1219 c, t dbSNP:537248708
1232 1232 a, c, t dbSNP:201243903
1233 1233 a, g dbSNP:34645321
1234 1234 a, c, g dbSNP:2307416
1240 1240 a, c dbSNP:752324753
1241 1241 -, a dbSNP:778081793
1248 1248 c, t dbSNP:767195966
1253 1253 g, t dbSNP:759006086
1255 1255 c, t dbSNP:773748252
1262 1262 a, g dbSNP:766275202
1271 1271 a, g dbSNP:368521829

Target ORF information:

RefSeq Version NM_001077481
Organism Homo sapiens (human)
Definition Homo sapiens nuclear receptor subfamily 1, group I, member 3 (NR1I3), transcript variant 4, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001077481

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
ATGGCCAGTA GGGAAGATGA GCTGAGGAAC TGTGTGGTAT GTGGGGACCA AGCCACAGGC 
TACCACTTTA ATGCGCTGAC TTGTGAGGGC TGCAAGGGTT TCTTCAGGAG AACAGTCAGC
AAAAGCATTG GTCCCACCTG CCCCTTTGCT GGAAGCTGTG AAGTCAGCAA GACTCAGAGG
CGCCACTGCC CAGCCTGCAG GTTGCAGAAG TGCTTAGATG CTGGCATGAG GAAAGACATG
ATACTGTCGG CAGAAGCCCT GGCATTGCGG CGAGCAAAGC AGGCCCAGCG GCGGGCACAG
CAAACACCTG TGCAACTGAG TAAGGAGCAA GAAGAGCTGA TCCGGACACT CCTGGGGGCC
CACACCCGCC ACATGGGCAC CATGTTTGAA CAGTTTGTGC AGTTTAGGCC TCCAGCTCAT
CTGTTCATCC ATCACCAGCC CTTGCCCACC CTGGCCCCTG TGCTGCCTCT GGTCACACAC
TTCGCAGACA TCAACACTTT CATGGTACTG CAAGTCATCA AGTTTACTAA GGACCTGCCC
GTCTTCCGTT CCCTGCCCAT TGAAGACCAG ATCTCCCTTC TCAAGGGAGC AGCTGTGGAA
ATCTGTCACA TCGTACTCAA TACCACTTTC TGTCTCCAAA CACAAAACTT CCTCTGCGGG
CCTCTTCGCT ACACAATTGA AGATGGAGCC CGTGCTCCCT ATCTTACAGA CCGACCTGGA
GTTACCCAGA GAGATGAGAT TGATCAGCTG CAAGAGGAGA TGGCACTGAC TCTGCAAAGC
TACATCAAGG GCCAGCAGCG AAGGCCCCGG GATCGGTTTC TGTATGCGAA GTTGCTAGGC
CTGCTGGCTG AGCTCCGGAG CATTAATGAG GCCTACGGGT ACCAAATCCA GCACATCCAG
GGCCTGTCTG CCATGATGCC GCTGCTCCAG GAGATCTGCA GCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu18640
Accession Version NM_001077482.2 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1074bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector Document: User manual_GenEZ ORF Clone Products.pdf (pdf)
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags Document: MSDS_GenEZ ORF Clone Products.pdf (pdf)
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product nuclear receptor subfamily 1 group I member 3 isoform 1
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from CB124867.1, DQ022681.1, BC121120.1 and AA918394.1. This sequence is a reference standard in the RefSeqGene project. On Jan 15, 2011 this sequence version replaced gi:117938755. Summary: This gene encodes a member of the nuclear receptor superfamily, and is a key regulator of xenobiotic and endobiotic metabolism. The protein binds to DNA as a monomer or a heterodimer with the retinoid X receptor and regulates the transcription of target genes involved in drug metabolism and bilirubin clearance, such as cytochrome P450 family members. Unlike most nuclear receptors, this transcriptional regulator is constitutively active in the absence of ligand but is regulated by both agonists and inverse agonists. Ligand binding results in translocation of this protein to the nucleus, where it activates or represses target gene transcription. These ligands include bilirubin, a variety of foreign compounds, steroid hormones, and prescription drugs. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]. Transcript Variant: This variant (1), also known as SV-25 or CAR2, represents the longest transcript and encodes the longest isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## CDS exon combination :: DQ022681.1 [ECO:0000331] RNAseq introns :: mixed/partial sample support SAMEA1968968, SAMEA1970526 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: full length.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
ATGGCCAGTA GGGAAGATGA GCTGAGGAAC TGTGTGGTAT GTGGGGACCA AGCCACAGGC 
TACCACTTTA ATGCGCTGAC TTGTGAGGGC TGCAAGGGTT TCTTCAGGAG AACAGTCAGC
AAAAGCATTG GTCCCACCTG CCCCTTTGCT GGAAGCTGTG AAGTCAGCAA GACTCAGAGG
CGCCACTGCC CAGCCTGCAG GTTGCAGAAG TGCTTAGATG CTGGCATGAG GAAAGACATG
ATACTGTCGG CAGAAGCCCT GGCATTGCGG CGAGCAAAGC AGGCCCAGCG GCGGGCACAG
CAAACACCTG TGCAACTGAG TAAGGAGCAA GAAGAGCTGA TCCGGACACT CCTGGGGGCC
CACACCCGCC ACATGGGCAC CATGTTTGAA CAGTTTGTGC AGTTTAGGCC TCCAGCTCAT
CTGTTCATCC ATCACCAGCC CTTGCCCACC CTGGCCCCTG TGCTGCCTCT GGTCACACAC
TTCGCAGACA TCAACACTTT CATGGTACTG CAAGTCATCA AGTTTACTAA GGACCTGCCC
GTCTTCCGTT CCCTGCCCAT TGAAGACCAG ATCTCCCTTC TCAAGGGAGC AGCTGTGGAA
ATCTGTCACA TCGTACTCAA TACCACTTTC TGTCTCCAAA CACAAAACTT CCTCTGCGGG
CCTCTTCGCT ACACAATTGA AGATGGAGCC CGTGTATCTC CCACAGTGGG GTTCCAGGTA
GAGTTTTTGG AGTTGCTCTT TCACTTCCAT GGAACACTAC GAAAACTGCA GCTCCAAGAG
CCTGAGTATG TGCTCTTGGC TGCCATGGCC CTCTTCTCTC CTGCTCCCTA TCTTACAGAC
CGACCTGGAG TTACCCAGAG AGATGAGATT GATCAGCTGC AAGAGGAGAT GGCACTGACT
CTGCAAAGCT ACATCAAGGG CCAGCAGCGA AGGCCCCGGG ATCGGTTTCT GTATGCGAAG
TTGCTAGGCC TGCTGGCTGA GCTCCGGAGC ATTAATGAGG CCTACGGGTA CCAAATCCAG
CACATCCAGG GCCTGTCTGC CATGATGCCG CTGCTCCAGG AGATCTGCAG CTGA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_001070950.1
CDS204..1277
Misc Feature(1)52..52(+)
Misc Feature(2)159..161(+)
Misc Feature(3)234..449(+)
Misc Feature(4)234..401(+)
Misc Feature(5)264..449(+)
Misc Feature(6)315..317(+)
Misc Feature(7)345..443(+)
Misc Feature(8)519..1268(+)
Misc Feature(9)681..1208(+)
Misc Feature(10)720..1268(+)
Misc Feature(11)936..1202(+)
Exon (1)1..170
Gene:NR1I3
Gene Synonym:
Exon (2)171..310
Gene:NR1I3
Gene Synonym:
Exon (3)311..441
Gene:NR1I3
Gene Synonym:
Exon (4)442..611
Gene:NR1I3
Gene Synonym:
Exon (5)612..751
Gene:NR1I3
Gene Synonym:
Exon (6)752..897
Gene:NR1I3
Gene Synonym:
Exon (7)898..1026
Gene:NR1I3
Gene Synonym:
Exon (8)1027..1147
Gene:NR1I3
Gene Synonym:
Exon (9)1148..1408
Gene:NR1I3
Gene Synonym:
Translation
Position Chain Variation Link
38 38 c, t dbSNP:762782589
65 65 a, c dbSNP:555012220
66 66 a, g dbSNP:538519022
98 98 a, g dbSNP:568943207
110 110 c, g dbSNP:746849019
114 114 a, t dbSNP:780391609
122 122 c, t dbSNP:758722723
124 124 c, t dbSNP:750479350
138 138 a, g dbSNP:765416900
139 139 c, g dbSNP:757636106
140 140 c, t dbSNP:754360419
144 144 a, g dbSNP:764563799
148 148 a, g dbSNP:376555075
152 152 a, t dbSNP:372090555
159 159 c, t dbSNP:181499203
161 161 a, g dbSNP:188975149
167 167 a, g, t dbSNP:769343586
185 185 a, c dbSNP:759962703
189 189 c, g dbSNP:376099705
191 191 a, g dbSNP:764847585
195 195 c, g, t dbSNP:776036693
200 200 c, t dbSNP:768587526
201 201 a, g dbSNP:2307415
206 206 a, g dbSNP:373168365
211 211 a, g dbSNP:775354866
218 218 a, c dbSNP:771986174
227 227 a, g dbSNP:745711502
230 230 -, g dbSNP:754115870
232 232 a, t dbSNP:779169935
246 246 a, g dbSNP:200774078
252 252 a, c dbSNP:749342923
277 277 a, c, t dbSNP:756548242
278 278 a, g dbSNP:140012276
288 288 c, g dbSNP:781707733
291 291 g, t dbSNP:755313912
293 293 c, t dbSNP:751908933
297 297 a, c dbSNP:764903201
311 311 -, gag dbSNP:764025470
312 312 a, c dbSNP:755509541
316 316 -, c dbSNP:760565010
317 317 a, c dbSNP:777971759
331 331 c, t dbSNP:747349033
337 337 a, c dbSNP:780293934
338 338 -, c dbSNP:775526201
338 338 c, t dbSNP:756865381
339 339 a, c dbSNP:753425575
345 345 c, g dbSNP:763894632
347 347 -, cc dbSNP:767358929
347 347 c, g dbSNP:544741783
348 348 c, t dbSNP:201089859
351 351 a, g dbSNP:752292550
352 352 c, t dbSNP:767517431
359 359 c, g dbSNP:759410250
360 360 g, t dbSNP:774131812
374 374 a, g dbSNP:766084148
379 379 a, t dbSNP:762865830
382 382 a, g dbSNP:142842008
383 383 g, t dbSNP:138077816
384 384 c, t dbSNP:748184864
385 385 a, g dbSNP:148277311
391 391 a, g, t dbSNP:747474209
392 392 a, c, t dbSNP:758672635
399 399 a, t dbSNP:565978374
400 400 g, t dbSNP:777533188
404 404 c, g dbSNP:755856811
416 416 a, c dbSNP:200078573
421 421 a, g dbSNP:112022118
429 429 a, g dbSNP:752198862
431 431 a, g dbSNP:548963536
436 436 -, aa dbSNP:759027156
447 447 c, t dbSNP:779436154
451 451 c, t dbSNP:373897043
452 452 a, g dbSNP:2307425
455 455 a, g dbSNP:781053597
461 461 c, g dbSNP:35205211
465 465 a, g dbSNP:751122638
472 472 a, g dbSNP:376162036
475 475 a, g dbSNP:531442743
483 483 a, c dbSNP:750159568
486 486 a, g dbSNP:563503102
491 491 a, g dbSNP:141229326
491 491 -, g dbSNP:776959559
492 492 c, t dbSNP:34161743
493 493 a, g dbSNP:368339212
496 496 a, g dbSNP:375295397
502 502 a, g dbSNP:764422186
505 505 a, g dbSNP:760638672
507 507 a, t dbSNP:775668216
514 514 c, t dbSNP:568686293
521 521 -, gagt dbSNP:768961218
534 534 a, g dbSNP:772403818
536 536 -, aga dbSNP:747407591
546 546 c, t dbSNP:376834028
547 547 a, g dbSNP:545723392
554 554 c, t dbSNP:146059027
555 555 c, g dbSNP:139629845
557 557 a, g dbSNP:370461642
559 559 a, g dbSNP:377243932
561 561 c, g dbSNP:768389092
565 565 a, c dbSNP:746456274
567 567 a, c dbSNP:779628611
568 568 c, g, t dbSNP:372603248
570 570 c, t dbSNP:778879440
571 571 a, g dbSNP:139473535
575 575 c, t dbSNP:753669717
577 577 c, g, t dbSNP:756377863
585 585 a, g dbSNP:752656803
586 586 c, t dbSNP:767632630
600 600 a, g dbSNP:149303773
606 606 c, t dbSNP:774980216
622 622 a, g dbSNP:752954187
629 629 c, t dbSNP:150598676
632 632 c, g dbSNP:755079453
634 634 a, g dbSNP:751720819
643 643 c, g dbSNP:369446796
647 647 a, g dbSNP:138159825
655 655 c, t dbSNP:773380358
658 658 c, t dbSNP:202054823
662 662 a, t dbSNP:762142599
671 671 c, t dbSNP:775185492
680 680 a, g, t dbSNP:745338458
686 686 c, t dbSNP:773871551
687 687 a, g dbSNP:375116822
689 689 a, c, t dbSNP:777632204
692 692 c, t dbSNP:367668454
700 700 c, t dbSNP:747937878
702 702 g, t dbSNP:781436406
706 706 c, t dbSNP:41270857
717 717 a, g dbSNP:751634864
733 733 -, a dbSNP:751138627
735 735 a, g dbSNP:780283429
736 736 a, c dbSNP:758616441
740 740 a, g dbSNP:750927922
743 743 c, t dbSNP:2307424
744 744 a, g dbSNP:143067018
750 750 c, t dbSNP:754182730
751 751 a, g dbSNP:767105877
758 758 a, g, t dbSNP:754170136
759 759 c, t dbSNP:764443927
761 761 c, t dbSNP:761088863
763 763 c, t dbSNP:564859096
780 780 c, g dbSNP:766064438
783 783 c, t dbSNP:772286234
814 814 c, t dbSNP:762489220
816 816 a, g dbSNP:772619920
817 817 g, t dbSNP:769715201
831 831 c, t dbSNP:746125471
838 838 a, t dbSNP:761662278
845 845 a, c dbSNP:776774308
860 860 c, t dbSNP:544805520
861 861 a, g dbSNP:746849037
863 863 a, g dbSNP:780391681
864 864 c, t dbSNP:772210168
870 870 c, t dbSNP:745909079
883 883 a, c dbSNP:778869769
893 893 c, t dbSNP:149864108
895 895 a, g dbSNP:145025028
896 896 c, t dbSNP:559151462
914 914 a, g dbSNP:774699125
916 916 g, t dbSNP:770895742
927 927 c, t dbSNP:146624074
928 928 c, t dbSNP:778217125
933 933 a, g dbSNP:756640389
937 937 -, t dbSNP:751049065
942 942 -, tttcacttc dbSNP:765857067
943 943 c, t dbSNP:398122411
951 951 c, t dbSNP:748454600
952 952 a, g dbSNP:201406656
957 957 a, g dbSNP:781415233
960 960 c, t dbSNP:755439721
963 963 a, c, g, t dbSNP:144211465
964 964 a, g dbSNP:753430504
991 991 a, g dbSNP:764070169
996 996 c, g dbSNP:760698101
1008 1008 a, g dbSNP:113800307
1009 1009 a, t dbSNP:775354782
1010 1010 a, g dbSNP:767209723
1023 1023 a, c dbSNP:1140627
1024 1024 c, t dbSNP:759426392
1025 1025 a, t dbSNP:66915105
1026 1026 a, g dbSNP:774408356
1035 1035 c, t dbSNP:777631690
1038 1038 a, g dbSNP:754957464
1043 1043 c, g, t dbSNP:201028035
1044 1044 c, t dbSNP:762797428
1045 1045 a, g dbSNP:142330499
1050 1050 a, g dbSNP:765481537
1061 1061 a, g dbSNP:761756373
1064 1064 a, g dbSNP:776791009
1068 1068 g, t dbSNP:768982496
1070 1070 c, g dbSNP:761248912
1072 1072 c, t dbSNP:775926630
1079 1079 c, g dbSNP:772550648
1090 1090 -, a dbSNP:769443369
1096 1096 c, t dbSNP:746281035
1124 1124 a, c dbSNP:199534928
1131 1131 c, t dbSNP:769594436
1132 1132 a, g dbSNP:200523878
1140 1140 c, t dbSNP:148675838
1141 1141 a, g dbSNP:754515980
1146 1146 c, t dbSNP:143583938
1147 1147 a, g dbSNP:114879683
1148 1148 g, t dbSNP:760125469
1156 1156 a, t dbSNP:775065775
1159 1159 c, t dbSNP:200408085
1160 1160 a, g dbSNP:36017137
1163 1163 c, g dbSNP:776318584
1164 1164 c, t dbSNP:768226364
1166 1166 a, g dbSNP:373127924
1168 1168 c, t dbSNP:774991039
1169 1169 a, c dbSNP:150124500
1170 1170 a, c, g, t dbSNP:2307414
1184 1184 a, g dbSNP:745800174
1188 1188 c, t dbSNP:369817002
1189 1189 a, g dbSNP:376397342
1191 1191 a, g dbSNP:770736555
1198 1198 a, t dbSNP:139722132
1203 1203 a, g dbSNP:749076282
1208 1208 c, t dbSNP:79799851
1209 1209 a, g dbSNP:756304664
1222 1222 a, g dbSNP:752758736
1223 1223 c, g dbSNP:781417564
1224 1224 c, t dbSNP:373882046
1230 1230 -, cagggcc dbSNP:779493594
1233 1233 c, g dbSNP:752094371
1252 1252 c, t dbSNP:758748494
1253 1253 a, g dbSNP:200228217
1256 1256 g, t dbSNP:141332323
1262 1262 a, g dbSNP:141389397
1268 1268 a, c dbSNP:369311646
1273 1273 a, c, g, t dbSNP:771557332
1279 1279 a, g dbSNP:140549301
1282 1282 a, g dbSNP:774313084
1284 1284 g, t dbSNP:376510791
1285 1285 c, t dbSNP:147849659
1290 1290 g, t dbSNP:777436441
1297 1297 c, t dbSNP:769779489
1305 1305 a, t dbSNP:748367918
1317 1317 a, c dbSNP:781617937
1326 1326 -, c dbSNP:771091045
1328 1328 a, g dbSNP:755081784
1335 1335 a, g dbSNP:751722876
1340 1340 c, t dbSNP:780564353
1341 1341 a, g dbSNP:755279262
1343 1343 -, t dbSNP:749380602
1346 1346 a, g dbSNP:3813629
1348 1348 c, t dbSNP:537248708
1361 1361 a, c, t dbSNP:201243903
1362 1362 a, g dbSNP:34645321
1363 1363 a, c, g dbSNP:2307416
1369 1369 a, c dbSNP:752324753
1370 1370 -, a dbSNP:778081793
1377 1377 c, t dbSNP:767195966
1382 1382 g, t dbSNP:759006086
1384 1384 c, t dbSNP:773748252
1391 1391 a, g dbSNP:766275202
1400 1400 a, g dbSNP:368521829

Target ORF information:

RefSeq Version NM_001077482
Organism Homo sapiens (human)
Definition Homo sapiens nuclear receptor subfamily 1, group I, member 3 (NR1I3), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001077482

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
ATGGCCAGTA GGGAAGATGA GCTGAGGAAC TGTGTGGTAT GTGGGGACCA AGCCACAGGC 
TACCACTTTA ATGCGCTGAC TTGTGAGGGC TGCAAGGGTT TCTTCAGGAG AACAGTCAGC
AAAAGCATTG GTCCCACCTG CCCCTTTGCT GGAAGCTGTG AAGTCAGCAA GACTCAGAGG
CGCCACTGCC CAGCCTGCAG GTTGCAGAAG TGCTTAGATG CTGGCATGAG GAAAGACATG
ATACTGTCGG CAGAAGCCCT GGCATTGCGG CGAGCAAAGC AGGCCCAGCG GCGGGCACAG
CAAACACCTG TGCAACTGAG TAAGGAGCAA GAAGAGCTGA TCCGGACACT CCTGGGGGCC
CACACCCGCC ACATGGGCAC CATGTTTGAA CAGTTTGTGC AGTTTAGGCC TCCAGCTCAT
CTGTTCATCC ATCACCAGCC CTTGCCCACC CTGGCCCCTG TGCTGCCTCT GGTCACACAC
TTCGCAGACA TCAACACTTT CATGGTACTG CAAGTCATCA AGTTTACTAA GGACCTGCCC
GTCTTCCGTT CCCTGCCCAT TGAAGACCAG ATCTCCCTTC TCAAGGGAGC AGCTGTGGAA
ATCTGTCACA TCGTACTCAA TACCACTTTC TGTCTCCAAA CACAAAACTT CCTCTGCGGG
CCTCTTCGCT ACACAATTGA AGATGGAGCC CGTGTATCTC CCACAGTGGG GTTCCAGGTA
GAGTTTTTGG AGTTGCTCTT TCACTTCCAT GGAACACTAC GAAAACTGCA GCTCCAAGAG
CCTGAGTATG TGCTCTTGGC TGCCATGGCC CTCTTCTCTC CTGCTCCCTA TCTTACAGAC
CGACCTGGAG TTACCCAGAG AGATGAGATT GATCAGCTGC AAGAGGAGAT GGCACTGACT
CTGCAAAGCT ACATCAAGGG CCAGCAGCGA AGGCCCCGGG ATCGGTTTCT GTATGCGAAG
TTGCTAGGCC TGCTGGCTGA GCTCCGGAGC ATTAATGAGG CCTACGGGTA CCAAATCCAG
CACATCCAGG GCCTGTCTGC CATGATGCCG CTGCTCCAGG AGATCTGCAG CTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu09461
Accession Version NM_001077473.2 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 948bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector Document: User manual_GenEZ ORF Clone Products.pdf (pdf)
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags Document: MSDS_GenEZ ORF Clone Products.pdf (pdf)
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product nuclear receptor subfamily 1 group I member 3 isoform 12
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from CB124867.1, AY572812.1 and AA918394.1. On Jan 15, 2011 this sequence version replaced gi:117938737. Summary: This gene encodes a member of the nuclear receptor superfamily, and is a key regulator of xenobiotic and endobiotic metabolism. The protein binds to DNA as a monomer or a heterodimer with the retinoid X receptor and regulates the transcription of target genes involved in drug metabolism and bilirubin clearance, such as cytochrome P450 family members. Unlike most nuclear receptors, this transcriptional regulator is constitutively active in the absence of ligand but is regulated by both agonists and inverse agonists. Ligand binding results in translocation of this protein to the nucleus, where it activates or represses target gene transcription. These ligands include bilirubin, a variety of foreign compounds, steroid hormones, and prescription drugs. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]. Transcript Variant: This variant (12), also known as SV-7, lacks an alternate in-frame exon in the 5' coding region and uses an alternate splice site in the 3' coding region, compared to variant 1. The resulting protein (isoform 12) is shorter, uses an upstream start codon, and has distinct N- and C-termini, compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY572812.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1968968, SAMEA1970526 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: full length.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
ATGCTGCCTA AGAGAAGCAG GAGAACAGTC AGCAAAAGCA TTGGTCCCAC CTGCCCCTTT 
GCTGGAAGCT GTGAAGTCAG CAAGACTCAG AGGCGCCACT GCCCAGCCTG CAGGTTGCAG
AAGTGCTTAG ATGCTGGCAT GAGGAAAGAC ATGATACTGT CGGCAGAAGC CCTGGCATTG
CGGCGAGCAA AGCAGGCCCA GCGGCGGGCA CAGCAAACAC CTGTGCAACT GAGTAAGGAG
CAAGAAGAGC TGATCCGGAC ACTCCTGGGG GCCCACACCC GCCACATGGG CACCATGTTT
GAACAGTTTG TGCAGTTTAG GCCTCCAGCT CATCTGTTCA TCCATCACCA GCCCTTGCCC
ACCCTGGCCC CTGTGCTGCC TCTGGTCACA CACTTCGCAG ACATCAACAC TTTCATGGTA
CTGCAAGTCA TCAAGTTTAC TAAGGACCTG CCCGTCTTCC GTTCCCTGCC CATTGAAGAC
CAGATCTCCC TTCTCAAGGG AGCAGCTGTG GAAATCTGTC ACATCGTACT CAATACCACT
TTCTGTCTCC AAACACAAAA CTTCCTCTGC GGGCCTCTTC GCTACACAAT TGAAGATGGA
GCCCGTGTAT CTCCCACAGT GGGGTTCCAG GTAGAGTTTT TGGAGTTGCT CTTTCACTTC
CATGGAACAC TACGAAAACT GCAGCTCCAA GAGCCTGAGT ATGTGCTCTT GGCTGCCATG
GCCCTCTTCT CTCCTGCTCC CTATCTTACA GACCGACCTG GAGTTACCCA GAGAGATGAG
ATTGATCAGC TGCAAGAGGA GATGGCACTG ACTCTGCAAA GCTACATCAA GGGCCAGCAG
CGAAGGCCCC GGGATCGCTC ACCTGGAACA CCCTGGATAC ACTGGAGTGG GAAAATGCTG
GGACCAAAGA TTGGGCCGGG TTCAAAGGGA GCCCAGTGGT TGCAATGA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_001070941.1
CDS151..1098
Misc Feature(1)52..52(+)
Misc Feature(2)169..309(+)
Misc Feature(3)172..306(+)
Misc Feature(4)202..261(+)
Misc Feature(5)379..1008(+)
Misc Feature(6)544..801(+)
Misc Feature(7)571..648(+)
Exon (1)1..170
Gene:NR1I3
Gene Synonym:
Exon (2)171..301
Gene:NR1I3
Gene Synonym:
Exon (3)302..471
Gene:NR1I3
Gene Synonym:
Exon (4)472..611
Gene:NR1I3
Gene Synonym:
Exon (5)612..757
Gene:NR1I3
Gene Synonym:
Exon (6)758..886
Gene:NR1I3
Gene Synonym:
Exon (7)887..1007
Gene:NR1I3
Gene Synonym:
Exon (8)1008..1114
Gene:NR1I3
Gene Synonym:
Translation
Position Chain Variation Link
38 38 c, t dbSNP:762782589
65 65 a, c dbSNP:555012220
66 66 a, g dbSNP:538519022
98 98 a, g dbSNP:568943207
110 110 c, g dbSNP:746849019
114 114 a, t dbSNP:780391609
122 122 c, t dbSNP:758722723
124 124 c, t dbSNP:750479350
138 138 a, g dbSNP:765416900
139 139 c, g dbSNP:757636106
140 140 c, t dbSNP:754360419
144 144 a, g dbSNP:764563799
148 148 a, g dbSNP:376555075
152 152 a, t dbSNP:372090555
159 159 c, t dbSNP:181499203
161 161 a, g dbSNP:188975149
167 167 a, g, t dbSNP:769343586
171 171 -, gag dbSNP:764025470
172 172 a, c dbSNP:755509541
176 176 -, c dbSNP:760565010
177 177 a, c dbSNP:777971759
191 191 c, t dbSNP:747349033
197 197 a, c dbSNP:780293934
198 198 -, c dbSNP:775526201
198 198 c, t dbSNP:756865381
199 199 a, c dbSNP:753425575
205 205 c, g dbSNP:763894632
207 207 -, cc dbSNP:767358929
207 207 c, g dbSNP:544741783
208 208 c, t dbSNP:201089859
211 211 a, g dbSNP:752292550
212 212 c, t dbSNP:767517431
219 219 c, g dbSNP:759410250
220 220 g, t dbSNP:774131812
234 234 a, g dbSNP:766084148
239 239 a, t dbSNP:762865830
242 242 a, g dbSNP:142842008
243 243 g, t dbSNP:138077816
244 244 c, t dbSNP:748184864
245 245 a, g dbSNP:148277311
251 251 a, g, t dbSNP:747474209
252 252 a, c, t dbSNP:758672635
259 259 a, t dbSNP:565978374
260 260 g, t dbSNP:777533188
264 264 c, g dbSNP:755856811
276 276 a, c dbSNP:200078573
281 281 a, g dbSNP:112022118
289 289 a, g dbSNP:752198862
291 291 a, g dbSNP:548963536
296 296 -, aa dbSNP:759027156
307 307 c, t dbSNP:779436154
311 311 c, t dbSNP:373897043
312 312 a, g dbSNP:2307425
315 315 a, g dbSN