||ORF Nucleotide Sequence (Length: 372bp)
||pcDNA3.1-C-(k)DYK or customized vector
|Tag on pcDNA3.1-C-(k)DYK
||C terminal DYKDDDDK tags
|ORF Insert Method
||CloneEZ® Seamless cloning technology
||Homo sapiens (human)
||potassium voltage-gated channel subfamily E member 2
||REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from AF302095.1.
This sequence is a reference standard in the RefSeqGene project.
Summary: Voltage-gated potassium (Kv) channels represent the most
complex class of voltage-gated ion channels from both functional
and structural standpoints. Their diverse functions include
regulating neurotransmitter release, heart rate, insulin secretion,
neuronal excitability, epithelial electrolyte transport, smooth
muscle contraction, and cell volume. This gene encodes a member of
the potassium channel, voltage-gated, isk-related subfamily. This
member is a small integral membrane subunit that assembles with the
KCNH2 gene product, a pore-forming protein, to alter its function.
This gene is expressed in heart and muscle and the gene mutations
are associated with cardiac arrhythmia. [provided by RefSeq, Jul
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
Transcript exon combination :: AF302095.1, BC112087.1 [ECO:0000332]
RNAseq introns :: single sample supports all introns
COMPLETENESS: complete on the 3' end.