||ORF Nucleotide Sequence (Length: 1380bp)
||pcDNA3.1-C-(k)DYK or customized vector
|Tag on pcDNA3.1-C-(k)DYK
||C terminal DYKDDDDK tags
|ORF Insert Method
||CloneEZ® Seamless cloning technology
||Mus musculus (house mouse)
||interleukin-7 receptor subunit alpha precursor
||VALIDATED REFSEQ: This record has undergone validation or
preliminary review. The reference sequence was derived from
BY776757.1, AK040364.1, AK042264.1 and BC089571.1.
On Feb 22, 2008 this sequence version replaced gi:45269151.
Summary: Interleukin-7 is a glycoptorein involved in the regulation
of lymphopoiesis. Response of cells to IL7 is dependent on the
presence of the interleukin 7 receptor (IL7R); the active receptor
is a alpha/gamma chain heterodimer. The gamma(c) chain, which also
associates with the interleukin-2 receptor, serves primarily to
activate signal transduction by the IL7R complex, while the alpha
chain of IL7R determines specific signaling events through its
association with cytoplasmic signaling molecules. [provided by
RefSeq, Jul 2008].
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
Transcript exon combination :: M29697.1, AK042264.1 [ECO:0000332]
RNAseq introns :: single sample supports all introns