The following Il7r gene sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Il7r gene which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
||ORF Nucleotide Sequence (Length: 1380bp)
||pcDNA3.1+/C-(K)DYK or customized vector
|Tag on pcDNA3.1+/C-(K)DYK
||C terminal DYKDDDDK tags
|ORF Insert Method
||CloneEZ® Seamless cloning technology
||Mus musculus (house mouse)
||interleukin-7 receptor subunit alpha precursor
||VALIDATED REFSEQ: This record has undergone validation or
preliminary review. The reference sequence was derived from
BY776757.1, AK040364.1, AK042264.1 and BC089571.1.
On Feb 22, 2008 this sequence version replaced gi:45269151.
Summary: Interleukin-7 is a glycoptorein involved in the regulation
of lymphopoiesis. Response of cells to IL7 is dependent on the
presence of the interleukin 7 receptor (IL7R); the active receptor
is a alpha/gamma chain heterodimer. The gamma(c) chain, which also
associates with the interleukin-2 receptor, serves primarily to
activate signal transduction by the IL7R complex, while the alpha
chain of IL7R determines specific signaling events through its
association with cytoplasmic signaling molecules. [provided by
RefSeq, Jul 2008].
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
Transcript exon combination :: M29697.1, AK042264.1 [ECO:0000332]
RNAseq introns :: single sample supports all introns