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Six3 cDNA ORF clone, Mus musculus (house mouse)

Gene Symbol Six3
Entrez Gene ID 20473
Full Name sine oculis-related homeobox 3
Synonyms E130112M24Rik, Six3a, Six3alpha, Six3b, Six3beta
General protein information
Preferred Names
homeobox protein SIX3
Names
homeobox protein SIX3
sine oculis homeobox homolog 3
sine oculis-related homeobox 3 homolog
Gene Type protein-coding
Organism Mus musculus (house mouse)
Genome

17

17 E4|17 55.42 cM

Summary lac of sum

mRNA and Protein(s)

mRNA Protein Name
NM_011381 NP_035511 homeobox protein SIX3


Homo sapiens (human) SIX3 NP_005404.1
Pan troglodytes (chimpanzee) SIX3 XP_525749.4
Canis lupus familiaris (dog) SIX3 XP_538477.4
Bos taurus (cattle) SIX3 NP_001180053.1
Mus musculus (house mouse) Six3 NP_035511.2
Rattus norvegicus (Norway rat) Six3 NP_076480.1
Gallus gallus (chicken) SIX3 NP_989695.1
Danio rerio (zebrafish) six3a NP_571437.1
Xenopus (Silurana) tropicalis (western clawed frog) six3 XP_002944388.2


GeneRIFs: Gene References Into Functions What's a GeneRIF?

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

The following Six3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Six3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OMu19606 NM_011381 Mus musculus sine oculis-related homeobox 3 (Six3), mRNA. pcDNA3.1+/C-(K)DYK or customized vector TBD $223.30
$319.00
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OMu19606
Clone ID Related Accession (Same CDS sequence) NM_011381
Accession Version NM_011381.4 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1002bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-FEB-2015
Organism Mus musculus (house mouse)
Product homeobox protein SIX3
Comment VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CD351258.1, BC098096.1 and AC166821.2. On Sep 17, 2009 this sequence version replaced gi:118130181. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC098096.1, D83145.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849388, SAMN00849390 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
ATGGTATTCC GCTCCCCCCT AGATCTCTAT TCCTCCCACT TCTTGTTGCC AAACTTCGCC 
GATTCTCACC ACTGCTCCCT ACTTCTGGCG AGTAGCGGCG GCGGGAGCGG TGCGAGCGGC
GGCGGCGGCG GCGCGGGAGG AGGCGGCGGC GGGAACCGTG CGGGAGGCGG CGGTGCTGGC
GGAGCAGGCG GCGGCAGCGG CGGCGGCGGC TCCAGGGCCC CCCCGGAAGA GTTGTCCATG
TTCCAGTTGC CCACCCTCAA CTTCTCGCCG GAGCAGGTGG CCAGCGTCTG CGAGACGCTG
GAGGAGACGG GCGACATCGA GCGGCTGGGC CGCTTCCTCT GGTCGCTGCC CGTGGCCCCC
GGGGCGTGCG AGGCCATCAA CAAACACGAG TCGATCCTGC GCGCGCGCGC TGTCGTCGCC
TTCCACACCG GCAACTTCCG CGACCTGTAC CACATCCTGG AGAACCACAA GTTCACTAAG
GAGTCTCACG GCAAGCTGCA AGCCATGTGG CTCGAGGCGC ACTACCAGGA GGCCGAGAAG
CTGCGCGGCC GCCCGCTCGG CCCGGTGGAC AAGTACCGCG TGCGCAAGAA GTTCCCTCTG
CCGCGCACCA TCTGGGATGG CGAGCAGAAG ACCCATTGCT TCAAGGAGCG GACTCGGAGC
CTGCTGCGGG AGTGGTACCT GCAGGATCCC TACCCCAACC CCAGCAAGAA ACGCGAACTG
GCGCAGGCCA CCGGCCTCAC CCCCACACAA GTAGGCAACT GGTTTAAGAA CCGGCGACAG
CGCGACCGCG CAGCGGCGGC CAAGAACAGG CTCCAGCATC AGGCCATCGG GCCGAGCGGG
ATGCGCTCGC TGGCCGAGCC CGGCTGCCCC ACGCACGGCT CAGCAGAGTC ACCGTCCACG
GCGGCCAGCC CGACCACCAG TGTGTCCAGC CTGACGGAGC GCGCGGACAC CGGCACTTCG
ATCCTCTCGG TAACCTCCAG CGACTCGGAA TGTGATGTAT GA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_035511.2
CDS407..1408
Misc Feature(1)17..19(+)
Misc Feature(2)1031..1177(+)
Misc Feature(3)1031..1177(+)
Misc Feature(4)1034..1177(+)
Exon (1)1..1215
Gene:Six3
Gene Synonym:
Exon (2)1216..3680
Gene:Six3
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_011381
Organism Mus musculus (house mouse)
Definition Mus musculus sine oculis-related homeobox 3 (Six3), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_011381

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
ATGGTATTCC GCTCCCCCCT AGATCTCTAT TCCTCCCACT TCTTGTTGCC AAACTTCGCC 
GATTCTCACC ACTGCTCCCT ACTTCTGGCG AGTAGCGGCG GCGGGAGCGG TGCGAGCGGC
GGCGGCGGCG GCGCGGGAGG AGGCGGCGGC GGGAACCGTG CGGGAGGCGG CGGTGCTGGC
GGAGCAGGCG GCGGCAGCGG CGGCGGCGGC TCCAGGGCCC CCCCGGAAGA GTTGTCCATG
TTCCAGTTGC CCACCCTCAA CTTCTCGCCG GAGCAGGTGG CCAGCGTCTG CGAGACGCTG
GAGGAGACGG GCGACATCGA GCGGCTGGGC CGCTTCCTCT GGTCGCTGCC CGTGGCCCCC
GGGGCGTGCG AGGCCATCAA CAAACACGAG TCGATCCTGC GCGCGCGCGC TGTCGTCGCC
TTCCACACCG GCAACTTCCG CGACCTGTAC CACATCCTGG AGAACCACAA GTTCACTAAG
GAGTCTCACG GCAAGCTGCA AGCCATGTGG CTCGAGGCGC ACTACCAGGA GGCCGAGAAG
CTGCGCGGCC GCCCGCTCGG CCCGGTGGAC AAGTACCGCG TGCGCAAGAA GTTCCCTCTG
CCGCGCACCA TCTGGGATGG CGAGCAGAAG ACCCATTGCT TCAAGGAGCG GACTCGGAGC
CTGCTGCGGG AGTGGTACCT GCAGGATCCC TACCCCAACC CCAGCAAGAA ACGCGAACTG
GCGCAGGCCA CCGGCCTCAC CCCCACACAA GTAGGCAACT GGTTTAAGAA CCGGCGACAG
CGCGACCGCG CAGCGGCGGC CAAGAACAGG CTCCAGCATC AGGCCATCGG GCCGAGCGGG
ATGCGCTCGC TGGCCGAGCC CGGCTGCCCC ACGCACGGCT CAGCAGAGTC ACCGTCCACG
GCGGCCAGCC CGACCACCAG TGTGTCCAGC CTGACGGAGC GCGCGGACAC CGGCACTTCG
ATCCTCTCGG TAACCTCCAG CGACTCGGAA TGTGATGTAT GA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

book

Location of transient ectodermal progenitor potential in mouse development
Development 140 (22), 4533-4543 (2013)
Li L, Liu C, Biechele S, Zhu Q, Song L, Lanner F, Jing N and Rossant J.


book

Genomic code for Sox2 binding uncovers its regulatory role in Six3 activation in the forebrain
Dev. Biol. 381 (2), 491-501 (2013)
Lee B, Song H, Rizzoti K, Son Y, Yoon J, Baek K and Jeong Y.


book

Forebrain deletion of the vesicular acetylcholine transporter results in deficits in executive function, metabolic, and RNA splicing abnormalities in the prefrontal cortex
J. Neurosci. 33 (37), 14908-14920 (2013)
Kolisnyk B, Al-Onaizi MA, Hirata PH, Guzman MS, Nikolova S, Barbash S, Soreq H, Bartha R, Prado MA and Prado VF.


book

Deficient FGF signaling causes optic nerve dysgenesis and ocular coloboma
Development 140 (13), 2711-2723 (2013)
Cai Z, Tao C, Li H, Ladher R, Gotoh N, Feng GS, Wang F and Zhang X.


book

Inhibition of Sox2-dependent activation of Shh in the ventral diencephalon by Tbx3 is required for formation of the neurohypophysis
Development 140 (11), 2299-2309 (2013)
Trowe MO, Zhao L, Weiss AC, Christoffels V, Epstein DJ and Kispert A.


book

rax, a novel paired-type homeobox gene, shows expression in the anterior neural fold and developing retina
Proc. Natl. Acad. Sci. U.S.A. 94 (7), 3088-3093 (1997)
Furukawa T, Kozak CA and Cepko CL.


book

Pituitary lineage determination by the Prophet of Pit-1 homeodomain factor defective in Ames dwarfism
Nature 384 (6607), 327-333 (1996)
Sornson MW, Wu W, Dasen JS, Flynn SE, Norman DJ, O'Connell SM, Gukovsky I, Carriere C, Ryan AK, Miller AP, Zuo L, Gleiberman AS, Andersen B, Beamer WG and Rosenfeld MG.


book

Identification and expression of six family genes in mouse retina
FEBS Lett. 393 (2-3), 259-263 (1996)
Kawakami K, Ohto H, Takizawa T and Saito T.


book

Six3, a murine homologue of the sine oculis gene, demarcates the most anterior border of the developing neural plate and is expressed during eye development
Development 121 (12), 4045-4055 (1995)
Oliver G, Mailhos A, Wehr R, Copeland NG, Jenkins NA and Gruss P.


book

Homeobox genes and connective tissue patterning
Development 121 (3), 693-705 (1995)
Oliver G, Wehr R, Jenkins NA, Copeland NG, Cheyette BN, Hartenstein V, Zipursky SL and Gruss P.


 
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