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Whrn whirlin [Mus musculus (house mouse)]

Gene Symbol Whrn
Entrez Gene ID 73750
Full Name whirlin
Synonyms 1110035G07Rik, AW122018, AW742671, C430046P22Rik, Dfnb31, wi
General protein information
Gene Type protein-coding
Organism Mus musculus (house mouse)
Genome

4

4 33.97 cM|4 C1

Summary This gene encodes a protein required for elongation and actin polymerization in the hair cell stereocilia. The encoded protein is localized to the cytoplasm and co-localizes with the growing end of actin filaments. Mutations in this gene have been linked to deafness. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2013]. lac of sum
Disorder MIM:

Disorder Html:
Alleles of this type are documented at Mouse Genome Informatics  (MGI)
CloneID RefSeq Accession Definition **Vector *Turnaround time Price
OMu33174 XM_006538309 PREDICTED: Mus musculus whirlin (Whrn), transcript variant X1, mRNA. pcDNA3.1-C-(k)DYK Not in stock -1 Starting from $99.00
OMu71056 XM_011250121 PREDICTED: Mus musculus whirlin (Whrn), transcript variant X3, mRNA. pcDNA3.1-C-(k)DYK Not in stock -1 Starting from $99.00
OMu71057 XM_011250122 PREDICTED: Mus musculus whirlin (Whrn), transcript variant X5, mRNA. pcDNA3.1-C-(k)DYK Not in stock -1 Starting from $99.00
OMu17750 NM_028640 Mus musculus whirlin (Whrn), transcript variant 1, mRNA. pcDNA3.1-C-(k)DYK Not in stock -1 Starting from $99.00
OMu17685 NM_001008791 Mus musculus whirlin (Whrn), transcript variant 2, mRNA. pcDNA3.1-C-(k)DYK Not in stock -1 Starting from $99.00
OMu17862 NM_001008792 Mus musculus whirlin (Whrn), transcript variant 3, mRNA. pcDNA3.1-C-(k)DYK Not in stock -1 Starting from $99.00
OMu17807 NM_001008793 Mus musculus whirlin (Whrn), transcript variant 4, mRNA. pcDNA3.1-C-(k)DYK Not in stock -1 Starting from $99.00
OMu17779 NM_001276371 Mus musculus whirlin (Whrn), transcript variant 10, mRNA. pcDNA3.1-C-(k)DYK Not in stock -1 Starting from $99.00

*Business Day
**You may select a custom vector to replace pcDNA3.1-C-(k)DYK after clone is added to cart.



CloneID OMu33174D
Sequence Information ORF Nucleotide Sequence (Length: 2754bp)
Protein sequence
SNP
Vector pcDNA3.1-C-(k)DYK or customized vector
Clone information Clone Map
Tag on pcDNA3.1-C-(k)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 09-FEB-2015
Organism Mus musculus (house mouse)
Product whirlin isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_187032.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Feb 9, 2015 this sequence version replaced gi:568927492. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
ATGAACGCAC AGCTGGACGG CCTGTCGGTG AGCTCGTCCT CCACCGGCTC GCTGGGCTCG 
GCGGCGGCGG CGGCGGGCGG CGGCGGGGGC GCGGGGTTGC GGCTGCTGTC TGCCAACGTG
CGCCAGCTGC ACCAAGCGCT CACGGCGCTG CTGAGCGAGC CCGAGCGGGA GCAGTTCACT
CACTGCCTCA ACGCGTACCA CGCGCGCCGC AACGTCTTCG ACCTGGTGCG CACCCTGCGC
GTCCTGCTGG ACAGCCCGGT CAAGCGGCGT CTGCTGCCCA TGCTGCGTCT GGTCATCCCG
CGCTCCGACC AGCTGCTCTT CGACCAGTAC ACGGCCGAGG GCCTCTACCT GCCAGCCACC
ACCCCCTACA GGCAGCCCGC CTGGGCCGCT CCCGACGGCG CGGGGCCCGG GGAGGTGCGA
CTCGTGAGCC TGCGGCGCGC CAAGGCCCAC GAGGGCTTGG GCTTCAGCAT CCGCGGGGGC
TCGGAACACG GCGTGGGCAT CTACGTGTCT CTAGTGGAGC CGGGCTCCCT GGCAGAGAAG
GAAGGGTTGC GGGTCGGGGA CCAGATTCTG CGCGTCAACG ATAAATCTCT AGCCCGGGTG
ACCCACGCGG AGGCTGTCAA GGCTCTCAAA GGCTCCAAGA AGCTGGTGCT GTCTGTATAC
TCAGCTGGGC GTATCCCAGG GGGCTATGTG ACCAACCACA TCTACACCTG GGTGGACCCA
CAGGGTCGAA GCACATCCCC TCCCTCCAGC CTGCCCCAGC CCCATGGCAG CACCCTGAGA
CAGCGTGAAG ATGACCGAAG GAGTACCCTC CACCTCCTGC AGAGTGGAGA TGAGAAAAAG
GTGAACCTGG TGTTGGGGGA CGGCCGGTCC TTGGGCCTCA CGATCCGAGG TGGAGCAGAG
TACGGCCTTG GCATTTACAT CACTGGTGTG GACCCAGGCT CTGAAGCAGA GAGCAGCGGC
CTCAAGGTTG GAGACCAGAT TCTGGAGGTG AATGGGCGGA GCTTTCTCAA CATCCTGCAT
GATGAGGCAG TGAAGCTGCT CAAGTCATCC CGGCACCTCA TCCTGACGGT GAAGGACGTC
GGAAGGCTGC CCCACGCACG TACCACCGTG GACCAGACCA AGTGGATCGC CAGTTCCCGG
ATCGGGGAAA GCGTCGCCAA CTCAGCAGGG TTTCCAGGGG ACCACACAGA AGAAGGGACA
AGCAAGCCAG GATTTTACAA GGGCCCAGCC GGCTCCCAGG TGACCCTGAG CAGCCTGGGG
AATCAGACTC GTGCACTGCT GGACGACCAA GCCAGGCACC TGCTGACAGA GCAGGAGCGC
GCCACCATGA TGTACTACCT GGCCCAGTAC CGTGGTGGCA CCATCTCTGT GGAGGCCATG
GTCATGGCAC TGTTTGAGTT GCTCAACACA CACGCCAAGT TCTCACTCCT GTCTGAGGTG
AGAAGCATCA TCTCACCCCA AGACCTGGAC CGCTTTGACC ACCTGGTGCT GAGGCGCGAG
ATCGAGTCTA TGAAGGCGAG GCAGCCCCCC GGCCCCGGGG TTGGAGACAC GTATTCCATG
GTTTCCTACA GCGACACAGG CTCATCCACA GGCAGCCACG GCACCTCTAC AACCGTCAGC
TCGGCCAGGG AGCGGCTGCT GTGGCTTATA GACCTGATGG AGAATACATT AGACCTGGAA
GGAACCGGTG AGACCACCCA GGGCAGCACC AACGCTCTCC CGGATGTGTC TGTGGATGAT
GTCAAATCCC CCTCAGAAGA TCTGCCTGGT ATCAAGCCAC CTCCTCCCCC ACCACCCCTG
GCTCAAGGTC ATGACCGCTT GCTTGGCCAG CCACGGAAGC CAGGGAGGGA GGACCCCGCA
CCTCTGTCTT CTGCTGCCCA CTCAGGCATT GTCTTCTCAG CACCACGGAA CCGCAGCCCG
CCGCCAGGGA CTGCTCCCAC TCCGGGACCT TCCTCAGCAC AGGACTCTCC CTCCTCCCCC
ATTTATGCCT CCATCTCCCA TGCCAACCCC AGTTCCAGAA AGCCGCTGGA CACCCACCTG
GCCCTGGTTA ACCAGCACCC CATCGGCCCC TTCCCTCGAG TCCAGTCCCC ACCTCACCTG
AAGAGCCCTC CTGCAGAGAC CCCAGGAGCT GGGGCCTGCC TTCCACCACC ATCACCCTCT
GAACACCCTG ACGCCGTGGG TGCAAACCAG CACTTTGTTC TGGTGGAGGT GCACCGTCCG
GACAGTGAGC CTGATGTGAA TGAAGTGCGG GCTCTGCCCC AGACTCGCAC CTCCACACTC
TCTCAGCTCT CAGACAGTGG GCAGACCCTG AGCGAGGACA GTGGCGTGGA TGCCGGGGAG
ACGGAGGCCA GCACCTCAGG CCGAGGCAGA CAGACAGCAT CCGCTAAGAA CAAGAATGGC
AAGGAGCAGC CCCGGACGGA GAGGACCGCG GAGGGTGCCA ACAAACCTCC CGGCCTGCTG
GAGCCAACGT CCACCCTGGT CCGTGTGAGG AAAAGTGCAG CCACACTGGG CATCGCCATT
GAGGGCGGTG CCAACACACG CCAGCCTCTG CCCAGGATCG TCACAATTCA GCGAGGAGGT
TCTGCCCATA ACTGTGGACA GCTCAAGGTG GGCCACGTAA TTCTGGAAGT GAATGGGCAG
ACACTTCGGG GTAAGGAGCA CAAGGAGGCC GCCCGAATCA TCGCTGAGGC CTTCAAGACC
AAGGAGAGAG ACTACATCGA CTTTCTGGTC ACTGAGTTCA ACGTGATGCT CTAG
The stop codons will be deleted if pcDNA3.1-C-(k)DYK vector is selected.
RefSeqXP_006538372.1
CDS845..3598
Misc Feature(1)956..1183(+)
Misc Feature(2)962..1045(+)
Misc Feature(3)1259..1492(+)
Misc Feature(4)1298..1474(+)
Misc Feature(5)1676..1918(+)
Misc Feature(6)1712..1888(+)
Misc Feature(7)2102..2344(+)
Misc Feature(8)2105..2197(+)
Misc Feature(9)3320..3535(+)
Misc Feature(10)3350..3529(+)
Translation
Position Chain Variation Link

Target ORF information:

RefSeq Version XM_006538309
Organism Mus musculus (house mouse)
Definition PREDICTED: Mus musculus whirlin (Whrn), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1-C-(k)DYK
XM_006538309

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
ATGAACGCAC AGCTGGACGG CCTGTCGGTG AGCTCGTCCT CCACCGGCTC GCTGGGCTCG 
GCGGCGGCGG CGGCGGGCGG CGGCGGGGGC GCGGGGTTGC GGCTGCTGTC TGCCAACGTG
CGCCAGCTGC ACCAAGCGCT CACGGCGCTG CTGAGCGAGC CCGAGCGGGA GCAGTTCACT
CACTGCCTCA ACGCGTACCA CGCGCGCCGC AACGTCTTCG ACCTGGTGCG CACCCTGCGC
GTCCTGCTGG ACAGCCCGGT CAAGCGGCGT CTGCTGCCCA TGCTGCGTCT GGTCATCCCG
CGCTCCGACC AGCTGCTCTT CGACCAGTAC ACGGCCGAGG GCCTCTACCT GCCAGCCACC
ACCCCCTACA GGCAGCCCGC CTGGGCCGCT CCCGACGGCG CGGGGCCCGG GGAGGTGCGA
CTCGTGAGCC TGCGGCGCGC CAAGGCCCAC GAGGGCTTGG GCTTCAGCAT CCGCGGGGGC
TCGGAACACG GCGTGGGCAT CTACGTGTCT CTAGTGGAGC CGGGCTCCCT GGCAGAGAAG
GAAGGGTTGC GGGTCGGGGA CCAGATTCTG CGCGTCAACG ATAAATCTCT AGCCCGGGTG
ACCCACGCGG AGGCTGTCAA GGCTCTCAAA GGCTCCAAGA AGCTGGTGCT GTCTGTATAC
TCAGCTGGGC GTATCCCAGG GGGCTATGTG ACCAACCACA TCTACACCTG GGTGGACCCA
CAGGGTCGAA GCACATCCCC TCCCTCCAGC CTGCCCCAGC CCCATGGCAG CACCCTGAGA
CAGCGTGAAG ATGACCGAAG GAGTACCCTC CACCTCCTGC AGAGTGGAGA TGAGAAAAAG
GTGAACCTGG TGTTGGGGGA CGGCCGGTCC TTGGGCCTCA CGATCCGAGG TGGAGCAGAG
TACGGCCTTG GCATTTACAT CACTGGTGTG GACCCAGGCT CTGAAGCAGA GAGCAGCGGC
CTCAAGGTTG GAGACCAGAT TCTGGAGGTG AATGGGCGGA GCTTTCTCAA CATCCTGCAT
GATGAGGCAG TGAAGCTGCT CAAGTCATCC CGGCACCTCA TCCTGACGGT GAAGGACGTC
GGAAGGCTGC CCCACGCACG TACCACCGTG GACCAGACCA AGTGGATCGC CAGTTCCCGG
ATCGGGGAAA GCGTCGCCAA CTCAGCAGGG TTTCCAGGGG ACCACACAGA AGAAGGGACA
AGCAAGCCAG GATTTTACAA GGGCCCAGCC GGCTCCCAGG TGACCCTGAG CAGCCTGGGG
AATCAGACTC GTGCACTGCT GGACGACCAA GCCAGGCACC TGCTGACAGA GCAGGAGCGC
GCCACCATGA TGTACTACCT GGCCCAGTAC CGTGGTGGCA CCATCTCTGT GGAGGCCATG
GTCATGGCAC TGTTTGAGTT GCTCAACACA CACGCCAAGT TCTCACTCCT GTCTGAGGTG
AGAAGCATCA TCTCACCCCA AGACCTGGAC CGCTTTGACC ACCTGGTGCT GAGGCGCGAG
ATCGAGTCTA TGAAGGCGAG GCAGCCCCCC GGCCCCGGGG TTGGAGACAC GTATTCCATG
GTTTCCTACA GCGACACAGG CTCATCCACA GGCAGCCACG GCACCTCTAC AACCGTCAGC
TCGGCCAGGG AGCGGCTGCT GTGGCTTATA GACCTGATGG AGAATACATT AGACCTGGAA
GGAACCGGTG AGACCACCCA GGGCAGCACC AACGCTCTCC CGGATGTGTC TGTGGATGAT
GTCAAATCCC CCTCAGAAGA TCTGCCTGGT ATCAAGCCAC CTCCTCCCCC ACCACCCCTG
GCTCAAGGTC ATGACCGCTT GCTTGGCCAG CCACGGAAGC CAGGGAGGGA GGACCCCGCA
CCTCTGTCTT CTGCTGCCCA CTCAGGCATT GTCTTCTCAG CACCACGGAA CCGCAGCCCG
CCGCCAGGGA CTGCTCCCAC TCCGGGACCT TCCTCAGCAC AGGACTCTCC CTCCTCCCCC
ATTTATGCCT CCATCTCCCA TGCCAACCCC AGTTCCAGAA AGCCGCTGGA CACCCACCTG
GCCCTGGTTA ACCAGCACCC CATCGGCCCC TTCCCTCGAG TCCAGTCCCC ACCTCACCTG
AAGAGCCCTC CTGCAGAGAC CCCAGGAGCT GGGGCCTGCC TTCCACCACC ATCACCCTCT
GAACACCCTG ACGCCGTGGG TGCAAACCAG CACTTTGTTC TGGTGGAGGT GCACCGTCCG
GACAGTGAGC CTGATGTGAA TGAAGTGCGG GCTCTGCCCC AGACTCGCAC CTCCACACTC
TCTCAGCTCT CAGACAGTGG GCAGACCCTG AGCGAGGACA GTGGCGTGGA TGCCGGGGAG
ACGGAGGCCA GCACCTCAGG CCGAGGCAGA CAGACAGCAT CCGCTAAGAA CAAGAATGGC
AAGGAGCAGC CCCGGACGGA GAGGACCGCG GAGGGTGCCA ACAAACCTCC CGGCCTGCTG
GAGCCAACGT CCACCCTGGT CCGTGTGAGG AAAAGTGCAG CCACACTGGG CATCGCCATT
GAGGGCGGTG CCAACACACG CCAGCCTCTG CCCAGGATCG TCACAATTCA GCGAGGAGGT
TCTGCCCATA ACTGTGGACA GCTCAAGGTG GGCCACGTAA TTCTGGAAGT GAATGGGCAG
ACACTTCGGG GTAAGGAGCA CAAGGAGGCC GCCCGAATCA TCGCTGAGGC CTTCAAGACC
AAGGAGAGAG ACTACATCGA CTTTCTGGTC ACTGAGTTCA ACGTGATGCT CTAG

The stop codons will be deleted if pcDNA3.1-C-(k)DYK vector is selected.


CloneID OMu71056D
Sequence Information ORF Nucleotide Sequence (Length: 1683bp)
Protein sequence
SNP
Vector pcDNA3.1-C-(k)DYK or customized vector
Clone information Clone Map
Tag on pcDNA3.1-C-(k)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 09-FEB-2015
Organism Mus musculus (house mouse)
Product whirlin isoform X2
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_187032.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
ATGAACGCAC AGCTGGACGG CCTGTCGGTG AGCTCGTCCT CCACCGGCTC GCTGGGCTCG 
GCGGCGGCGG CGGCGGGCGG CGGCGGGGGC GCGGGGTTGC GGCTGCTGTC TGCCAACGTG
CGCCAGCTGC ACCAAGCGCT CACGGCGCTG CTGAGCGAGC CCGAGCGGGA GCAGTTCACT
CACTGCCTCA ACGCGTACCA CGCGCGCCGC AACGTCTTCG ACCTGGTGCG CACCCTGCGC
GTCCTGCTGG ACAGCCCGGT CAAGCGGCGT CTGCTGCCCA TGCTGCGTCT GGTCATCCCG
CGCTCCGACC AGCTGCTCTT CGACCAGTAC ACGGCCGAGG GCCTCTACCT GCCAGCCACC
ACCCCCTACA GGCAGCCCGC CTGGGCCGCT CCCGACGGCG CGGGGCCCGG GGAGGTGCGA
CTCGTGAGCC TGCGGCGCGC CAAGGCCCAC GAGGGCTTGG GCTTCAGCAT CCGCGGGGGC
TCGGAACACG GCGTGGGCAT CTACGTGTCT CTAGTGGAGC CGGGCTCCCT GGCAGAGAAG
GAAGGGTTGC GGGTCGGGGA CCAGATTCTG CGCGTCAACG ATAAATCTCT AGCCCGGGTG
ACCCACGCGG AGGCTGTCAA GGCTCTCAAA GGCTCCAAGA AGCTGGTGCT GTCTGTATAC
TCAGCTGGGC GTATCCCAGG GGGCTATGTG ACCAACCACA TCTACACCTG GGTGGACCCA
CAGGGTCGAA GCACATCCCC TCCCTCCAGC CTGCCCCAGC CCCATGGCAG CACCCTGAGA
CAGCGTGAAG ATGACCGAAG GAGTACCCTC CACCTCCTGC AGAGTGGAGA TGAGAAAAAG
GTGAACCTGG TGTTGGGGGA CGGCCGGTCC TTGGGCCTCA CGATCCGAGG TGGAGCAGAG
TACGGCCTTG GCATTTACAT CACTGGTGTG GACCCAGGCT CTGAAGCAGA GAGCAGCGGC
CTCAAGGTTG GAGACCAGAT TCTGGAGGTG AATGGGCGGA GCTTTCTCAA CATCCTGCAT
GATGAGGCAG TGAAGCTGCT CAAGTCATCC CGGCACCTCA TCCTGACGGT GAAGGACGTC
GGAAGGCTGC CCCACGCACG TACCACCGTG GACCAGACCA AGTGGATCGC CAGTTCCCGG
ATCGGGGAAA GCGTCGCCAA CTCAGCAGGG TTTCCAGGGG ACCACACAGA AGAAGGGACA
AGCAAGCCAG GATTTTACAA GGGCCCAGCC GGCTCCCAGG TGACCCTGAG CAGCCTGGGG
AATCAGACTC GTGCACTGCT GGACGACCAA GCCAGGCACC TGCTGACAGA GCAGGAGCGC
GCCACCATGA TGTACTACCT GGCCCAGTAC CGTGGTGGCA CCATCTCTGT GGAGGCCATG
GTCATGGCAC TGTTTGAGTT GCTCAACACA CACGCCAAGT TCTCACTCCT GTCTGAGGTG
AGAAGCATCA TCTCACCCCA AGACCTGGAC CGCTTTGACC ACCTGGTGCT GAGGCGCGAG
ATCGAGTCTA TGAAGGCGAG GCAGCCCCCC GGCCCCGGGG TTGGAGACAC GTATTCCATG
GTTTCCTACA GCGACACAGG CTCATCCACA GGCAGCCACG GCACCTCTAC AACCGTCAGC
TCGGCCAGGG TGAGCCACCC CTGCCCTATC CTTGAATACA TTAGACCTGG AAGGAACCGG
TGA
The stop codons will be deleted if pcDNA3.1-C-(k)DYK vector is selected.
RefSeqXP_011248423.1
CDS846..2528
Misc Feature(1)957..1184(+)
Misc Feature(2)963..1046(+)
Misc Feature(3)1260..1493(+)
Misc Feature(4)1299..1475(+)
Misc Feature(5)1677..1919(+)
Misc Feature(6)1713..1889(+)
Misc Feature(7)2103..2345(+)
Misc Feature(8)2106..2198(+)
Translation
Position Chain Variation Link

Target ORF information:

RefSeq Version XM_011250121
Organism Mus musculus (house mouse)
Definition PREDICTED: Mus musculus whirlin (Whrn), transcript variant X3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1-C-(k)DYK
XM_011250121

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
ATGAACGCAC AGCTGGACGG CCTGTCGGTG AGCTCGTCCT CCACCGGCTC GCTGGGCTCG 
GCGGCGGCGG CGGCGGGCGG CGGCGGGGGC GCGGGGTTGC GGCTGCTGTC TGCCAACGTG
CGCCAGCTGC ACCAAGCGCT CACGGCGCTG CTGAGCGAGC CCGAGCGGGA GCAGTTCACT
CACTGCCTCA ACGCGTACCA CGCGCGCCGC AACGTCTTCG ACCTGGTGCG CACCCTGCGC
GTCCTGCTGG ACAGCCCGGT CAAGCGGCGT CTGCTGCCCA TGCTGCGTCT GGTCATCCCG
CGCTCCGACC AGCTGCTCTT CGACCAGTAC ACGGCCGAGG GCCTCTACCT GCCAGCCACC
ACCCCCTACA GGCAGCCCGC CTGGGCCGCT CCCGACGGCG CGGGGCCCGG GGAGGTGCGA
CTCGTGAGCC TGCGGCGCGC CAAGGCCCAC GAGGGCTTGG GCTTCAGCAT CCGCGGGGGC
TCGGAACACG GCGTGGGCAT CTACGTGTCT CTAGTGGAGC CGGGCTCCCT GGCAGAGAAG
GAAGGGTTGC GGGTCGGGGA CCAGATTCTG CGCGTCAACG ATAAATCTCT AGCCCGGGTG
ACCCACGCGG AGGCTGTCAA GGCTCTCAAA GGCTCCAAGA AGCTGGTGCT GTCTGTATAC
TCAGCTGGGC GTATCCCAGG GGGCTATGTG ACCAACCACA TCTACACCTG GGTGGACCCA
CAGGGTCGAA GCACATCCCC TCCCTCCAGC CTGCCCCAGC CCCATGGCAG CACCCTGAGA
CAGCGTGAAG ATGACCGAAG GAGTACCCTC CACCTCCTGC AGAGTGGAGA TGAGAAAAAG
GTGAACCTGG TGTTGGGGGA CGGCCGGTCC TTGGGCCTCA CGATCCGAGG TGGAGCAGAG
TACGGCCTTG GCATTTACAT CACTGGTGTG GACCCAGGCT CTGAAGCAGA GAGCAGCGGC
CTCAAGGTTG GAGACCAGAT TCTGGAGGTG AATGGGCGGA GCTTTCTCAA CATCCTGCAT
GATGAGGCAG TGAAGCTGCT CAAGTCATCC CGGCACCTCA TCCTGACGGT GAAGGACGTC
GGAAGGCTGC CCCACGCACG TACCACCGTG GACCAGACCA AGTGGATCGC CAGTTCCCGG
ATCGGGGAAA GCGTCGCCAA CTCAGCAGGG TTTCCAGGGG ACCACACAGA AGAAGGGACA
AGCAAGCCAG GATTTTACAA GGGCCCAGCC GGCTCCCAGG TGACCCTGAG CAGCCTGGGG
AATCAGACTC GTGCACTGCT GGACGACCAA GCCAGGCACC TGCTGACAGA GCAGGAGCGC
GCCACCATGA TGTACTACCT GGCCCAGTAC CGTGGTGGCA CCATCTCTGT GGAGGCCATG
GTCATGGCAC TGTTTGAGTT GCTCAACACA CACGCCAAGT TCTCACTCCT GTCTGAGGTG
AGAAGCATCA TCTCACCCCA AGACCTGGAC CGCTTTGACC ACCTGGTGCT GAGGCGCGAG
ATCGAGTCTA TGAAGGCGAG GCAGCCCCCC GGCCCCGGGG TTGGAGACAC GTATTCCATG
GTTTCCTACA GCGACACAGG CTCATCCACA GGCAGCCACG GCACCTCTAC AACCGTCAGC
TCGGCCAGGG TGAGCCACCC CTGCCCTATC CTTGAATACA TTAGACCTGG AAGGAACCGG
TGA

The stop codons will be deleted if pcDNA3.1-C-(k)DYK vector is selected.


CloneID OMu71057D
Sequence Information ORF Nucleotide Sequence (Length: 1635bp)
Protein sequence
SNP
Vector pcDNA3.1-C-(k)DYK or customized vector
Clone information Clone Map
Tag on pcDNA3.1-C-(k)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 09-FEB-2015
Organism Mus musculus (house mouse)
Product whirlin isoform X3
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_187032.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
ATGAACGCAC AGCTGGACGG CCTGTCGGTG AGCTCGTCCT CCACCGGCTC GCTGGGCTCG 
GCGGCGGCGG CGGCGGGCGG CGGCGGGGGC GCGGGGTTGC GGCTGCTGTC TGCCAACGTG
CGCCAGCTGC ACCAAGCGCT CACGGCGCTG CTGAGCGAGC CCGAGCGGGA GCAGTTCACT
CACTGCCTCA ACGCGTACCA CGCGCGCCGC AACGTCTTCG ACCTGGTGCG CACCCTGCGC
GTCCTGCTGG ACAGCCCGGT CAAGCGGCGT CTGCTGCCCA TGCTGCGTCT GGTCATCCCG
CGCTCCGACC AGCTGCTCTT CGACCAGTAC ACGGCCGAGG GCCTCTACCT GCCAGCCACC
ACCCCCTACA GGCAGCCCGC CTGGGCCGCT CCCGACGGCG CGGGGCCCGG GGAGGTGCGA
CTCGTGAGCC TGCGGCGCGC CAAGGCCCAC GAGGGCTTGG GCTTCAGCAT CCGCGGGGGC
TCGGAACACG GCGTGGGCAT CTACGTGTCT CTAGTGGAGC CGGGCTCCCT GGCAGAGAAG
GAAGGGTTGC GGGTCGGGGA CCAGATTCTG CGCGTCAACG ATAAATCTCT AGCCCGGGTG
ACCCACGCGG AGGCTGTCAA GGCTCTCAAA GGCTCCAAGA AGCTGGTGCT GTCTGTATAC
TCAGCTGGGC GTATCCCAGG GGGCTATGTG ACCAACCACA TCTACACCTG GGTGGACCCA
CAGGGTCGAA GCACATCCCC TCCCTCCAGC CTGCCCCAGC CCCATGGCAG CACCCTGAGA
CAGCGTGAAG ATGACCGAAG GAGTACCCTC CACCTCCTGC AGAGTGGAGA TGAGAAAAAG
GTGAACCTGG TGTTGGGGGA CGGCCGGTCC TTGGGCCTCA CGATCCGAGG TGGAGCAGAG
TACGGCCTTG GCATTTACAT CACTGGTGTG GACCCAGGCT CTGAAGCAGA GAGCAGCGGC
CTCAAGGTTG GAGACCAGAT TCTGGAGGTG AATGGGCGGA GCTTTCTCAA CATCCTGCAT
GATGAGGCAG TGAAGCTGCT CAAGTCATCC CGGCACCTCA TCCTGACGGT GAAGGACGTC
GGAAGGCTGC CCCACGCACG TACCACCGTG GACCAGACCA AGTGGATCGC CAGTTCCCGG
ATCGGGGAAA GCGTCGCCAA CTCAGCAGGG TTTCCAGGGG ACCACACAGA AGAAGGGACA
AGCAAGCCAG GATTTTACAA GGGCCCAGCC GGCTCCCAGG TGACCCTGAG CAGCCTGGGG
AATCAGACTC GTGCACTGCT GGACGACCAA GCCAGGCACC TGCTGACAGA GCAGGAGCGC
GCCACCATGA TGTACTACCT GGCCCAGTAC CGTGGTGGCA CCATCTCTGT GGAGGCCATG
GTCATGGCAC TGTTTGAGTT GCTCAACACA CACGCCAAGT TCTCACTCCT GTCTGAGGTG
AGAAGCATCA TCTCACCCCA AGACCTGGAC CGCTTTGACC ACCTGGTGCT GAGGCGCGAG
ATCGAGTCTA TGAAGGCGAG GCAGCCCCCC GGCCCCGGGG TTGGAGACAC GTATTCCATG
GTTTCCTACA GCGACACAGG CTCATCCACA GGCAGCCACG GCACCTCTAC AACCGTCAGC
TCGGCCAGGG TGTGA
The stop codons will be deleted if pcDNA3.1-C-(k)DYK vector is selected.
RefSeqXP_011248424.1
CDS846..2480
Misc Feature(1)957..1184(+)
Misc Feature(2)963..1046(+)
Misc Feature(3)1260..1493(+)
Misc Feature(4)1299..1475(+)
Misc Feature(5)1677..1919(+)
Misc Feature(6)1713..1889(+)
Misc Feature(7)2103..2345(+)
Misc Feature(8)2106..2198(+)
Translation
Position Chain Variation Link

Target ORF information:

RefSeq Version XM_011250122
Organism Mus musculus (house mouse)
Definition PREDICTED: Mus musculus whirlin (Whrn), transcript variant X5, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1-C-(k)DYK
XM_011250122

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
ATGAACGCAC AGCTGGACGG CCTGTCGGTG AGCTCGTCCT CCACCGGCTC GCTGGGCTCG 
GCGGCGGCGG CGGCGGGCGG CGGCGGGGGC GCGGGGTTGC GGCTGCTGTC TGCCAACGTG
CGCCAGCTGC ACCAAGCGCT CACGGCGCTG CTGAGCGAGC CCGAGCGGGA GCAGTTCACT
CACTGCCTCA ACGCGTACCA CGCGCGCCGC AACGTCTTCG ACCTGGTGCG CACCCTGCGC
GTCCTGCTGG ACAGCCCGGT CAAGCGGCGT CTGCTGCCCA TGCTGCGTCT GGTCATCCCG
CGCTCCGACC AGCTGCTCTT CGACCAGTAC ACGGCCGAGG GCCTCTACCT GCCAGCCACC
ACCCCCTACA GGCAGCCCGC CTGGGCCGCT CCCGACGGCG CGGGGCCCGG GGAGGTGCGA
CTCGTGAGCC TGCGGCGCGC CAAGGCCCAC GAGGGCTTGG GCTTCAGCAT CCGCGGGGGC
TCGGAACACG GCGTGGGCAT CTACGTGTCT CTAGTGGAGC CGGGCTCCCT GGCAGAGAAG
GAAGGGTTGC GGGTCGGGGA CCAGATTCTG CGCGTCAACG ATAAATCTCT AGCCCGGGTG
ACCCACGCGG AGGCTGTCAA GGCTCTCAAA GGCTCCAAGA AGCTGGTGCT GTCTGTATAC
TCAGCTGGGC GTATCCCAGG GGGCTATGTG ACCAACCACA TCTACACCTG GGTGGACCCA
CAGGGTCGAA GCACATCCCC TCCCTCCAGC CTGCCCCAGC CCCATGGCAG CACCCTGAGA
CAGCGTGAAG ATGACCGAAG GAGTACCCTC CACCTCCTGC AGAGTGGAGA TGAGAAAAAG
GTGAACCTGG TGTTGGGGGA CGGCCGGTCC TTGGGCCTCA CGATCCGAGG TGGAGCAGAG
TACGGCCTTG GCATTTACAT CACTGGTGTG GACCCAGGCT CTGAAGCAGA GAGCAGCGGC
CTCAAGGTTG GAGACCAGAT TCTGGAGGTG AATGGGCGGA GCTTTCTCAA CATCCTGCAT
GATGAGGCAG TGAAGCTGCT CAAGTCATCC CGGCACCTCA TCCTGACGGT GAAGGACGTC
GGAAGGCTGC CCCACGCACG TACCACCGTG GACCAGACCA AGTGGATCGC CAGTTCCCGG
ATCGGGGAAA GCGTCGCCAA CTCAGCAGGG TTTCCAGGGG ACCACACAGA AGAAGGGACA
AGCAAGCCAG GATTTTACAA GGGCCCAGCC GGCTCCCAGG TGACCCTGAG CAGCCTGGGG
AATCAGACTC GTGCACTGCT GGACGACCAA GCCAGGCACC TGCTGACAGA GCAGGAGCGC
GCCACCATGA TGTACTACCT GGCCCAGTAC CGTGGTGGCA CCATCTCTGT GGAGGCCATG
GTCATGGCAC TGTTTGAGTT GCTCAACACA CACGCCAAGT TCTCACTCCT GTCTGAGGTG
AGAAGCATCA TCTCACCCCA AGACCTGGAC CGCTTTGACC ACCTGGTGCT GAGGCGCGAG
ATCGAGTCTA TGAAGGCGAG GCAGCCCCCC GGCCCCGGGG TTGGAGACAC GTATTCCATG
GTTTCCTACA GCGACACAGG CTCATCCACA GGCAGCCACG GCACCTCTAC AACCGTCAGC
TCGGCCAGGG TGTGA

The stop codons will be deleted if pcDNA3.1-C-(k)DYK vector is selected.


CloneID OMu17750D
Sequence Information ORF Nucleotide Sequence (Length: 2724bp)
Protein sequence
SNP
Vector pcDNA3.1-C-(k)DYK or customized vector
Clone information Clone Map
Tag on pcDNA3.1-C-(k)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-FEB-2015
Organism Mus musculus (house mouse)
Product whirlin isoform 1
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK157955.1 and AY739114.1. On Feb 9, 2013 this sequence version replaced gi:57012339. Summary: This gene encodes a protein required for elongation and actin polymerization in the hair cell stereocilia. The encoded protein is localized to the cytoplasm and co-localizes with the growing end of actin filaments. Mutations in this gene have been linked to deafness. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2013]. Transcript Variant: This variant (1) lacks an in-frame exon in the 3' coding region, compared to variant 2. The encoded isoform (1) is shorter than isoform 2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY739114.1, BC150757.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
ATGAACGCAC AGCTGGACGG CCTGTCGGTG AGCTCGTCCT CCACCGGCTC GCTGGGCTCG 
GCGGCGGCGG CGGCGGGCGG CGGCGGGGGC GCGGGGTTGC GGCTGCTGTC TGCCAACGTG
CGCCAGCTGC ACCAAGCGCT CACGGCGCTG CTGAGCGAGC CCGAGCGGGA GCAGTTCACT
CACTGCCTCA ACGCGTACCA CGCGCGCCGC AACGTCTTCG ACCTGGTGCG CACCCTGCGC
GTCCTGCTGG ACAGCCCGGT CAAGCGGCGT CTGCTGCCCA TGCTGCGTCT GGTCATCCCG
CGCTCCGACC AGCTGCTCTT CGACCAGTAC ACGGCCGAGG GCCTCTACCT GCCAGCCACC
ACCCCCTACA GGCAGCCCGC CTGGGCCGCT CCCGACGGCG CGGGGCCCGG GGAGGTGCGA
CTCGTGAGCC TGCGGCGCGC CAAGGCCCAC GAGGGCTTGG GCTTCAGCAT CCGCGGGGGC
TCGGAACACG GCGTGGGCAT CTACGTGTCT CTAGTGGAGC CGGGCTCCCT GGCAGAGAAG
GAAGGGTTGC GGGTCGGGGA CCAGATTCTG CGCGTCAACG ATAAATCTCT AGCCCGGGTG
ACCCACGCGG AGGCTGTCAA GGCTCTCAAA GGCTCCAAGA AGCTGGTGCT GTCTGTATAC
TCAGCTGGGC GTATCCCAGG GGGCTATGTG ACCAACCACA TCTACACCTG GGTGGACCCA
CAGGGTCGAA GCACATCCCC TCCCTCCAGC CTGCCCCAGC CCCATGGCAG CACCCTGAGA
CAGCGTGAAG ATGACCGAAG GAGTACCCTC CACCTCCTGC AGAGTGGAGA TGAGAAAAAG
GTGAACCTGG TGTTGGGGGA CGGCCGGTCC TTGGGCCTCA CGATCCGAGG TGGAGCAGAG
TACGGCCTTG GCATTTACAT CACTGGTGTG GACCCAGGCT CTGAAGCAGA GAGCAGCGGC
CTCAAGGTTG GAGACCAGAT TCTGGAGGTG AATGGGCGGA GCTTTCTCAA CATCCTGCAT
GATGAGGCAG TGAAGCTGCT CAAGTCATCC CGGCACCTCA TCCTGACGGT GAAGGACGTC
GGAAGGCTGC CCCACGCACG TACCACCGTG GACCAGACCA AGTGGATCGC CAGTTCCCGG
ATCGGGGAAA GCGTCGCCAA CTCAGCAGGG TTTCCAGGGG ACCACACAGA AGAAGGGACA
AGCAAGCCAG GATTTTACAA GGGCCCAGCC GGCTCCCAGG TGACCCTGAG CAGCCTGGGG
AATCAGACTC GTGCACTGCT GGACGACCAA GCCAGGCACC TGCTGACAGA GCAGGAGCGC
GCCACCATGA TGTACTACCT GGCCCAGTAC CGTGGTGGCA CCATCTCTGT GGAGGCCATG
GTCATGGCAC TGTTTGAGTT GCTCAACACA CACGCCAAGT TCTCACTCCT GTCTGAGGTG
AGAAGCATCA TCTCACCCCA AGACCTGGAC CGCTTTGACC ACCTGGTGCT GAGGCGCGAG
ATCGAGTCTA TGAAGGCGAG GCAGCCCCCC GGCCCCGGGG TTGGAGACAC GTATTCCATG
GTTTCCTACA GCGACACAGG CTCATCCACA GGCAGCCACG GCACCTCTAC AACCGTCAGC
TCGGCCAGGA ATACATTAGA CCTGGAAGGA ACCGGTGAGA CCACCCAGGG CAGCACCAAC
GCTCTCCCGG ATGTGTCTGT GGATGATGTC AAATCCCCCT CAGAAGATCT GCCTGGTATC
AAGCCACCTC CTCCCCCACC ACCCCTGGCT CAAGGTCATG ACCGCTTGCT TGGCCAGCCA
CGGAAGCCAG GGAGGGAGGA CCCCGCACCT CTGTCTTCTG CTGCCCACTC AGGCATTGTC
TTCTCAGCAC CACGGAACCG CAGCCCGCCG CCAGGGACTG CTCCCACTCC GGGACCTTCC
TCAGCACAGG ACTCTCCCTC CTCCCCCATT TATGCCTCCA TCTCCCATGC CAACCCCAGT
TCCAGAAAGC CGCTGGACAC CCACCTGGCC CTGGTTAACC AGCACCCCAT CGGCCCCTTC
CCTCGAGTCC AGTCCCCACC TCACCTGAAG AGCCCTCCTG CAGAGACCCC AGGAGCTGGG
GCCTGCCTTC CACCACCATC ACCCTCTGAA CACCCTGACG CCGTGGGTGC AAACCAGCAC
TTTGTTCTGG TGGAGGTGCA CCGTCCGGAC AGTGAGCCTG ATGTGAATGA AGTGCGGGCT
CTGCCCCAGA CTCGCACAGC CTCCACACTC TCTCAGCTCT CAGACAGTGG GCAGACCCTG
AGCGAGGACA GTGGCGTGGA TGCCGGGGAG ACGGAGGCCA GCACCTCAGG CCGAGGCAGA
CAGACAGCAT CCGCTAAGAA CAAGAATGGC AAGGAGCAGC CCCGGACGGA GAGGACCGCG
GAGGGTGCCA ACAAACCTCC CGGCCTGCTG GAGCCAACGT CCACCCTGGT CCGTGTGAGG
AAAAGTGCAG CCACACTGGG CATCGCCATT GAGGGCGGTG CCAACACACG CCAGCCTCTG
CCCAGGATCG TCACAATTCA GCGAGGAGGT TCTGCCCATA ACTGTGGACA GCTCAAGGTG
GGCCACGTAA TTCTGGAAGT GAATGGGCAG ACACTTCGGG GTAAGGAGCA CAAGGAGGCC
GCCCGAATCA TCGCTGAGGC CTTCAAGACC AAGGAGAGAG ACTACATCGA CTTTCTGGTC
ACTGAGTTCA ACGTGATGCT CTAG
The stop codons will be deleted if pcDNA3.1-C-(k)DYK vector is selected.
RefSeqNP_082916.1
CDS759..3482
Misc Feature(1)606..608(+)
Misc Feature(2)870..1097(+)
Misc Feature(3)876..959(+)
Misc Feature(4)1173..1406(+)
Misc Feature(5)1212..1388(+)
Misc Feature(6)1590..1832(+)
Misc Feature(7)1626..1802(+)
Misc Feature(8)2016..2258(+)
Misc Feature(9)2019..2111(+)
Misc Feature(10)3204..3419(+)
Misc Feature(11)3234..3413(+)
Exon (1)1..1379
Gene:Whrn
Gene Synonym:
Exon (2)1380..1598
Gene:Whrn
Gene Synonym:
Exon (3)1599..1724
Gene:Whrn
Gene Synonym:
Exon (4)1725..1927
Gene:Whrn
Gene Synonym:
Exon (5)1928..1964
Gene:Whrn
Gene Synonym:
Exon (6)1965..2177
Gene:Whrn
Gene Synonym:
Exon (7)2178..2387
Gene:Whrn
Gene Synonym:
Exon (8)2388..2459
Gene:Whrn
Gene Synonym:
Exon (9)2460..2994
Gene:Whrn
Gene Synonym:
Exon (10)2995..3176
Gene:Whrn
Gene Synonym:
Exon (11)3177..3299
Gene:Whrn
Gene Synonym:
Exon (12)3300..4056
Gene:Whrn
Gene Synonym:
Translation
Position Chain Variation Link
413 413 -, cc dbSNP:235470811
893 893 a, g dbSNP:258826663
926 926 a, g dbSNP:221632230
993 993 c, t dbSNP:222841310
1061 1061 c, t dbSNP:253973828
1146 1146 a, g dbSNP:242225030
1162 1162 a, g dbSNP:258949563
1436 1436 a, t dbSNP:229464781
1448 1448 c, g dbSNP:248885091
1543 1543 a, g dbSNP:231349128
1655 1655 a, c dbSNP:237155388
1793 1793 a, g dbSNP:247019404
1934 1934 a, g dbSNP:265066394
2117 2117 c, t dbSNP:229444216
2118 2118 a, g dbSNP:257642857
2159 2159 a, g dbSNP:239773439
2198 2198 a, g dbSNP:27920291
2229 2229 c, t dbSNP:27920292
2255 2255 a, c dbSNP:232567681
2267 2267 c, t dbSNP:215654097
2277 2277 a, c dbSNP:263626317
2288 2288 c, g dbSNP:240313724
2330 2330 c, t dbSNP:212181156
2336 2336 a, g dbSNP:27920293
2411 2411 c, t dbSNP:27920358
2439 2439 a, g dbSNP:27920359
2447 2447 a, g dbSNP:213669003
2581 2581 a, c dbSNP:27920368
2582 2582 c, t dbSNP:224589614
2585 2585 a, t dbSNP:263759692
2669 2669 a, g dbSNP:240663587
2885 2885 c, t dbSNP:222457121
2898 2898 a, g dbSNP:247882268
2924 2924 c, t dbSNP:230379038
3027 3027 g, t dbSNP:264208410
3156 3156 c, g, t dbSNP:27920380
3185 3185 a, g dbSNP:256865838
3398 3398 c, t dbSNP:232997001
3403 3403 a, g dbSNP:27920395
3452 3452 c, t dbSNP:27920396
3496 3496 g, t dbSNP:235537939
3530 3530 c, t dbSNP:212416980
3555 3555 c, t dbSNP:254567383
3562 3562 a, g dbSNP:236434904
3568 3568 c, t dbSNP:215479081
3716 3716 a, g dbSNP:252080788
3758 3758 a, c dbSNP:227907253
3792 3792 a, g dbSNP:260402776
3849 3849 a, c dbSNP:248430395
3854 3854 c, t dbSNP:224190694
3897 3897 -, attt dbSNP:251337007
3919 3919 -, c dbSNP:386975477
3928 3928 -, cc dbSNP:233005657
3929 3929 -, ccc dbSNP:244841204
3930 3930 a, c dbSNP:47785708
3954 3954 c, t dbSNP:261916909

Target ORF information:

RefSeq Version NM_028640
Organism Mus musculus (house mouse)
Definition Mus musculus whirlin (Whrn), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1-C-(k)DYK
NM_028640

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
ATGAACGCAC AGCTGGACGG CCTGTCGGTG AGCTCGTCCT CCACCGGCTC GCTGGGCTCG 
GCGGCGGCGG CGGCGGGCGG CGGCGGGGGC GCGGGGTTGC GGCTGCTGTC TGCCAACGTG
CGCCAGCTGC ACCAAGCGCT CACGGCGCTG CTGAGCGAGC CCGAGCGGGA GCAGTTCACT
CACTGCCTCA ACGCGTACCA CGCGCGCCGC AACGTCTTCG ACCTGGTGCG CACCCTGCGC
GTCCTGCTGG ACAGCCCGGT CAAGCGGCGT CTGCTGCCCA TGCTGCGTCT GGTCATCCCG
CGCTCCGACC AGCTGCTCTT CGACCAGTAC ACGGCCGAGG GCCTCTACCT GCCAGCCACC
ACCCCCTACA GGCAGCCCGC CTGGGCCGCT CCCGACGGCG CGGGGCCCGG GGAGGTGCGA
CTCGTGAGCC TGCGGCGCGC CAAGGCCCAC GAGGGCTTGG GCTTCAGCAT CCGCGGGGGC
TCGGAACACG GCGTGGGCAT CTACGTGTCT CTAGTGGAGC CGGGCTCCCT GGCAGAGAAG
GAAGGGTTGC GGGTCGGGGA CCAGATTCTG CGCGTCAACG ATAAATCTCT AGCCCGGGTG
ACCCACGCGG AGGCTGTCAA GGCTCTCAAA GGCTCCAAGA AGCTGGTGCT GTCTGTATAC
TCAGCTGGGC GTATCCCAGG GGGCTATGTG ACCAACCACA TCTACACCTG GGTGGACCCA
CAGGGTCGAA GCACATCCCC TCCCTCCAGC CTGCCCCAGC CCCATGGCAG CACCCTGAGA
CAGCGTGAAG ATGACCGAAG GAGTACCCTC CACCTCCTGC AGAGTGGAGA TGAGAAAAAG
GTGAACCTGG TGTTGGGGGA CGGCCGGTCC TTGGGCCTCA CGATCCGAGG TGGAGCAGAG
TACGGCCTTG GCATTTACAT CACTGGTGTG GACCCAGGCT CTGAAGCAGA GAGCAGCGGC
CTCAAGGTTG GAGACCAGAT TCTGGAGGTG AATGGGCGGA GCTTTCTCAA CATCCTGCAT
GATGAGGCAG TGAAGCTGCT CAAGTCATCC CGGCACCTCA TCCTGACGGT GAAGGACGTC
GGAAGGCTGC CCCACGCACG TACCACCGTG GACCAGACCA AGTGGATCGC CAGTTCCCGG
ATCGGGGAAA GCGTCGCCAA CTCAGCAGGG TTTCCAGGGG ACCACACAGA AGAAGGGACA
AGCAAGCCAG GATTTTACAA GGGCCCAGCC GGCTCCCAGG TGACCCTGAG CAGCCTGGGG
AATCAGACTC GTGCACTGCT GGACGACCAA GCCAGGCACC TGCTGACAGA GCAGGAGCGC
GCCACCATGA TGTACTACCT GGCCCAGTAC CGTGGTGGCA CCATCTCTGT GGAGGCCATG
GTCATGGCAC TGTTTGAGTT GCTCAACACA CACGCCAAGT TCTCACTCCT GTCTGAGGTG
AGAAGCATCA TCTCACCCCA AGACCTGGAC CGCTTTGACC ACCTGGTGCT GAGGCGCGAG
ATCGAGTCTA TGAAGGCGAG GCAGCCCCCC GGCCCCGGGG TTGGAGACAC GTATTCCATG
GTTTCCTACA GCGACACAGG CTCATCCACA GGCAGCCACG GCACCTCTAC AACCGTCAGC
TCGGCCAGGA ATACATTAGA CCTGGAAGGA ACCGGTGAGA CCACCCAGGG CAGCACCAAC
GCTCTCCCGG ATGTGTCTGT GGATGATGTC AAATCCCCCT CAGAAGATCT GCCTGGTATC
AAGCCACCTC CTCCCCCACC ACCCCTGGCT CAAGGTCATG ACCGCTTGCT TGGCCAGCCA
CGGAAGCCAG GGAGGGAGGA CCCCGCACCT CTGTCTTCTG CTGCCCACTC AGGCATTGTC
TTCTCAGCAC CACGGAACCG CAGCCCGCCG CCAGGGACTG CTCCCACTCC GGGACCTTCC
TCAGCACAGG ACTCTCCCTC CTCCCCCATT TATGCCTCCA TCTCCCATGC CAACCCCAGT
TCCAGAAAGC CGCTGGACAC CCACCTGGCC CTGGTTAACC AGCACCCCAT CGGCCCCTTC
CCTCGAGTCC AGTCCCCACC TCACCTGAAG AGCCCTCCTG CAGAGACCCC AGGAGCTGGG
GCCTGCCTTC CACCACCATC ACCCTCTGAA CACCCTGACG CCGTGGGTGC AAACCAGCAC
TTTGTTCTGG TGGAGGTGCA CCGTCCGGAC AGTGAGCCTG ATGTGAATGA AGTGCGGGCT
CTGCCCCAGA CTCGCACAGC CTCCACACTC TCTCAGCTCT CAGACAGTGG GCAGACCCTG
AGCGAGGACA GTGGCGTGGA TGCCGGGGAG ACGGAGGCCA GCACCTCAGG CCGAGGCAGA
CAGACAGCAT CCGCTAAGAA CAAGAATGGC AAGGAGCAGC CCCGGACGGA GAGGACCGCG
GAGGGTGCCA ACAAACCTCC CGGCCTGCTG GAGCCAACGT CCACCCTGGT CCGTGTGAGG
AAAAGTGCAG CCACACTGGG CATCGCCATT GAGGGCGGTG CCAACACACG CCAGCCTCTG
CCCAGGATCG TCACAATTCA GCGAGGAGGT TCTGCCCATA ACTGTGGACA GCTCAAGGTG
GGCCACGTAA TTCTGGAAGT GAATGGGCAG ACACTTCGGG GTAAGGAGCA CAAGGAGGCC
GCCCGAATCA TCGCTGAGGC CTTCAAGACC AAGGAGAGAG ACTACATCGA CTTTCTGGTC
ACTGAGTTCA ACGTGATGCT CTAG

The stop codons will be deleted if pcDNA3.1-C-(k)DYK vector is selected.


CloneID OMu17685D
Sequence Information ORF Nucleotide Sequence (Length: 2757bp)
Protein sequence
SNP
Vector pcDNA3.1-C-(k)DYK or customized vector
Clone information Clone Map
Tag on pcDNA3.1-C-(k)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-FEB-2015
Organism Mus musculus (house mouse)
Product whirlin isoform 2
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK157955.1 and AY739115.1. On Feb 9, 2013 this sequence version replaced gi:57012337. Summary: This gene encodes a protein required for elongation and actin polymerization in the hair cell stereocilia. The encoded protein is localized to the cytoplasm and co-localizes with the growing end of actin filaments. Mutations in this gene have been linked to deafness. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2013]. Transcript Variant: This variant (2) represents the longest transcript and encodes the longest isoform (2). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY739115.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
ATGAACGCAC AGCTGGACGG CCTGTCGGTG AGCTCGTCCT CCACCGGCTC GCTGGGCTCG 
GCGGCGGCGG CGGCGGGCGG CGGCGGGGGC GCGGGGTTGC GGCTGCTGTC TGCCAACGTG
CGCCAGCTGC ACCAAGCGCT CACGGCGCTG CTGAGCGAGC CCGAGCGGGA GCAGTTCACT
CACTGCCTCA ACGCGTACCA CGCGCGCCGC AACGTCTTCG ACCTGGTGCG CACCCTGCGC
GTCCTGCTGG ACAGCCCGGT CAAGCGGCGT CTGCTGCCCA TGCTGCGTCT GGTCATCCCG
CGCTCCGACC AGCTGCTCTT CGACCAGTAC ACGGCCGAGG GCCTCTACCT GCCAGCCACC
ACCCCCTACA GGCAGCCCGC CTGGGCCGCT CCCGACGGCG CGGGGCCCGG GGAGGTGCGA
CTCGTGAGCC TGCGGCGCGC CAAGGCCCAC GAGGGCTTGG GCTTCAGCAT CCGCGGGGGC
TCGGAACACG GCGTGGGCAT CTACGTGTCT CTAGTGGAGC CGGGCTCCCT GGCAGAGAAG
GAAGGGTTGC GGGTCGGGGA CCAGATTCTG CGCGTCAACG ATAAATCTCT AGCCCGGGTG
ACCCACGCGG AGGCTGTCAA GGCTCTCAAA GGCTCCAAGA AGCTGGTGCT GTCTGTATAC
TCAGCTGGGC GTATCCCAGG GGGCTATGTG ACCAACCACA TCTACACCTG GGTGGACCCA
CAGGGTCGAA GCACATCCCC TCCCTCCAGC CTGCCCCAGC CCCATGGCAG CACCCTGAGA
CAGCGTGAAG ATGACCGAAG GAGTACCCTC CACCTCCTGC AGAGTGGAGA TGAGAAAAAG
GTGAACCTGG TGTTGGGGGA CGGCCGGTCC TTGGGCCTCA CGATCCGAGG TGGAGCAGAG
TACGGCCTTG GCATTTACAT CACTGGTGTG GACCCAGGCT CTGAAGCAGA GAGCAGCGGC
CTCAAGGTTG GAGACCAGAT TCTGGAGGTG AATGGGCGGA GCTTTCTCAA CATCCTGCAT
GATGAGGCAG TGAAGCTGCT CAAGTCATCC CGGCACCTCA TCCTGACGGT GAAGGACGTC
GGAAGGCTGC CCCACGCACG TACCACCGTG GACCAGACCA AGTGGATCGC CAGTTCCCGG
ATCGGGGAAA GCGTCGCCAA CTCAGCAGGG TTTCCAGGGG ACCACACAGA AGAAGGGACA
AGCAAGCCAG GATTTTACAA GGGCCCAGCC GGCTCCCAGG TGACCCTGAG CAGCCTGGGG
AATCAGACTC GTGCACTGCT GGACGACCAA GCCAGGCACC TGCTGACAGA GCAGGAGCGC
GCCACCATGA TGTACTACCT GGCCCAGTAC CGTGGTGGCA CCATCTCTGT GGAGGCCATG
GTCATGGCAC TGTTTGAGTT GCTCAACACA CACGCCAAGT TCTCACTCCT GTCTGAGGTG
AGAAGCATCA TCTCACCCCA AGACCTGGAC CGCTTTGACC ACCTGGTGCT GAGGCGCGAG
ATCGAGTCTA TGAAGGCGAG GCAGCCCCCC GGCCCCGGGG TTGGAGACAC GTATTCCATG
GTTTCCTACA GCGACACAGG CTCATCCACA GGCAGCCACG GCACCTCTAC AACCGTCAGC
TCGGCCAGGG AGCGGCTGCT GTGGCTTATA GACCTGATGG AGAATACATT AGACCTGGAA
GGAACCGGTG AGACCACCCA GGGCAGCACC AACGCTCTCC CGGATGTGTC TGTGGATGAT
GTCAAATCCC CCTCAGAAGA TCTGCCTGGT ATCAAGCCAC CTCCTCCCCC ACCACCCCTG
GCTCAAGGTC ATGACCGCTT GCTTGGCCAG CCACGGAAGC CAGGGAGGGA GGACCCCGCA
CCTCTGTCTT CTGCTGCCCA CTCAGGCATT GTCTTCTCAG CACCACGGAA CCGCAGCCCG
CCGCCAGGGA CTGCTCCCAC TCCGGGACCT TCCTCAGCAC AGGACTCTCC CTCCTCCCCC
ATTTATGCCT CCATCTCCCA TGCCAACCCC AGTTCCAGAA AGCCGCTGGA CACCCACCTG
GCCCTGGTTA ACCAGCACCC CATCGGCCCC TTCCCTCGAG TCCAGTCCCC ACCTCACCTG
AAGAGCCCTC CTGCAGAGAC CCCAGGAGCT GGGGCCTGCC TTCCACCACC ATCACCCTCT
GAACACCCTG ACGCCGTGGG TGCAAACCAG CACTTTGTTC TGGTGGAGGT GCACCGTCCG
GACAGTGAGC CTGATGTGAA TGAAGTGCGG GCTCTGCCCC AGACTCGCAC AGCCTCCACA
CTCTCTCAGC TCTCAGACAG TGGGCAGACC CTGAGCGAGG ACAGTGGCGT GGATGCCGGG
GAGACGGAGG CCAGCACCTC AGGCCGAGGC AGACAGACAG CATCCGCTAA GAACAAGAAT
GGCAAGGAGC AGCCCCGGAC GGAGAGGACC GCGGAGGGTG CCAACAAACC TCCCGGCCTG
CTGGAGCCAA CGTCCACCCT GGTCCGTGTG AGGAAAAGTG CAGCCACACT GGGCATCGCC
ATTGAGGGCG GTGCCAACAC ACGCCAGCCT CTGCCCAGGA TCGTCACAAT TCAGCGAGGA
GGTTCTGCCC ATAACTGTGG ACAGCTCAAG GTGGGCCACG TAATTCTGGA AGTGAATGGG
CAGACACTTC GGGGTAAGGA GCACAAGGAG GCCGCCCGAA TCATCGCTGA GGCCTTCAAG
ACCAAGGAGA GAGACTACAT CGACTTTCTG GTCACTGAGT TCAACGTGAT GCTCTAG
The stop codons will be deleted if pcDNA3.1-C-(k)DYK vector is selected.
RefSeqNP_001008791.1
CDS759..3515
Misc Feature(1)606..608(+)
Misc Feature(2)870..1097(+)
Misc Feature(3)876..959(+)
Misc Feature(4)1173..1406(+)
Misc Feature(5)1212..1388(+)
Misc Feature(6)1590..1832(+)
Misc Feature(7)1626..1802(+)
Misc Feature(8)2016..2258(+)
Misc Feature(9)2019..2111(+)
Misc Feature(10)3237..3452(+)
Misc Feature(11)3267..3446(+)
Exon (1)1..1379
Gene:Whrn
Gene Synonym:
Exon (2)1380..1598
Gene:Whrn
Gene Synonym:
Exon (3)1599..1724
Gene:Whrn
Gene Synonym:
Exon (4)1725..1927
Gene:Whrn
Gene Synonym:
Exon (5)1928..1964
Gene:Whrn
Gene Synonym:
Exon (6)1965..2177
Gene:Whrn
Gene Synonym:
Exon (7)2178..2387
Gene:Whrn
Gene Synonym:
Exon (8)2388..2420
Gene:Whrn
Gene Synonym:
Exon (9)2421..2492
Gene:Whrn
Gene Synonym:
Exon (10)2493..3027
Gene:Whrn
Gene Synonym:
Exon (11)3028..3209
Gene:Whrn
Gene Synonym:
Exon (12)3210..3332
Gene:Whrn
Gene Synonym:
Exon (13)3333..4089
Gene:Whrn
Gene Synonym:
Translation
Position Chain Variation Link
413 413 -, cc dbSNP:235470811
893 893 a, g dbSNP:258826663
926 926 a, g dbSNP:221632230
993 993 c, t dbSNP:222841310
1061 1061 c, t dbSNP:253973828
1146 1146 a, g dbSNP:242225030
1162 1162 a, g dbSNP:258949563
1436 1436 a, t dbSNP:229464781
1448 1448 c, g dbSNP:248885091
1543 1543 a, g dbSNP:231349128
1655 1655 a, c dbSNP:237155388
1793 1793 a, g dbSNP:247019404
1934 1934 a, g dbSNP:265066394
2117 2117 c, t dbSNP:229444216
2118 2118 a, g dbSNP:257642857
2159 2159 a, g dbSNP:239773439
2198 2198 a, g dbSNP:27920291
2229 2229 c, t dbSNP:27920292
2255 2255 a, c dbSNP:232567681
2267 2267 c, t dbSNP:215654097
2277 2277 a, c dbSNP:263626317
2288 2288 c, g dbSNP:240313724
2330 2330 c, t dbSNP:212181156
2336 2336 a, g dbSNP:27920293
2444 2444 c, t dbSNP:27920358
2472 2472 a, g dbSNP:27920359
2480 2480 a, g dbSNP:213669003
2614 2614 a, c dbSNP:27920368
2615 2615 c, t dbSNP:224589614
2618 2618 a, t dbSNP:263759692
2702 2702 a, g dbSNP:240663587
2918 2918 c, t dbSNP:222457121
2931 2931 a, g dbSNP:247882268
2957 2957 c, t dbSNP:230379038
3060 3060 g, t dbSNP:264208410
3189 3189 c, g, t dbSNP:27920380
3218 3218 a, g dbSNP:256865838
3431 3431 c, t dbSNP:232997001
3436 3436 a, g dbSNP:27920395
3485 3485 c, t dbSNP:27920396
3529 3529 g, t dbSNP:235537939
3563 3563 c, t dbSNP:212416980
3588 3588 c, t dbSNP:254567383
3595 3595 a, g dbSNP:236434904
3601 3601 c, t dbSNP:215479081
3749 3749 a, g dbSNP:252080788
3791 3791 a, c dbSNP:227907253
3825 3825 a, g dbSNP:260402776
3882 3882 a, c dbSNP:248430395
3887 3887 c, t dbSNP:224190694
3930 3930 -, attt dbSNP:251337007
3952 3952 -, c dbSNP:386975477
3961 3961 -, cc dbSNP:233005657
3962 3962 -, ccc dbSNP:244841204
3963 3963 a, c dbSNP:47785708
3987 3987 c, t dbSNP:261916909

Target ORF information:

RefSeq Version NM_001008791
Organism Mus musculus (house mouse)
Definition Mus musculus whirlin (Whrn), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1-C-(k)DYK
NM_001008791

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
ATGAACGCAC AGCTGGACGG CCTGTCGGTG AGCTCGTCCT CCACCGGCTC GCTGGGCTCG 
GCGGCGGCGG CGGCGGGCGG CGGCGGGGGC GCGGGGTTGC GGCTGCTGTC TGCCAACGTG
CGCCAGCTGC ACCAAGCGCT CACGGCGCTG CTGAGCGAGC CCGAGCGGGA GCAGTTCACT
CACTGCCTCA ACGCGTACCA CGCGCGCCGC AACGTCTTCG ACCTGGTGCG CACCCTGCGC
GTCCTGCTGG ACAGCCCGGT CAAGCGGCGT CTGCTGCCCA TGCTGCGTCT GGTCATCCCG
CGCTCCGACC AGCTGCTCTT CGACCAGTAC ACGGCCGAGG GCCTCTACCT GCCAGCCACC
ACCCCCTACA GGCAGCCCGC CTGGGCCGCT CCCGACGGCG CGGGGCCCGG GGAGGTGCGA
CTCGTGAGCC TGCGGCGCGC CAAGGCCCAC GAGGGCTTGG GCTTCAGCAT CCGCGGGGGC
TCGGAACACG GCGTGGGCAT CTACGTGTCT CTAGTGGAGC CGGGCTCCCT GGCAGAGAAG
GAAGGGTTGC GGGTCGGGGA CCAGATTCTG CGCGTCAACG ATAAATCTCT AGCCCGGGTG
ACCCACGCGG AGGCTGTCAA GGCTCTCAAA GGCTCCAAGA AGCTGGTGCT GTCTGTATAC
TCAGCTGGGC GTATCCCAGG GGGCTATGTG ACCAACCACA TCTACACCTG GGTGGACCCA
CAGGGTCGAA GCACATCCCC TCCCTCCAGC CTGCCCCAGC CCCATGGCAG CACCCTGAGA
CAGCGTGAAG ATGACCGAAG GAGTACCCTC CACCTCCTGC AGAGTGGAGA TGAGAAAAAG
GTGAACCTGG TGTTGGGGGA CGGCCGGTCC TTGGGCCTCA CGATCCGAGG TGGAGCAGAG
TACGGCCTTG GCATTTACAT CACTGGTGTG GACCCAGGCT CTGAAGCAGA GAGCAGCGGC
CTCAAGGTTG GAGACCAGAT TCTGGAGGTG AATGGGCGGA GCTTTCTCAA CATCCTGCAT
GATGAGGCAG TGAAGCTGCT CAAGTCATCC CGGCACCTCA TCCTGACGGT GAAGGACGTC
GGAAGGCTGC CCCACGCACG TACCACCGTG GACCAGACCA AGTGGATCGC CAGTTCCCGG
ATCGGGGAAA GCGTCGCCAA CTCAGCAGGG TTTCCAGGGG ACCACACAGA AGAAGGGACA
AGCAAGCCAG GATTTTACAA GGGCCCAGCC GGCTCCCAGG TGACCCTGAG CAGCCTGGGG
AATCAGACTC GTGCACTGCT GGACGACCAA GCCAGGCACC TGCTGACAGA GCAGGAGCGC
GCCACCATGA TGTACTACCT GGCCCAGTAC CGTGGTGGCA CCATCTCTGT GGAGGCCATG
GTCATGGCAC TGTTTGAGTT GCTCAACACA CACGCCAAGT TCTCACTCCT GTCTGAGGTG
AGAAGCATCA TCTCACCCCA AGACCTGGAC CGCTTTGACC ACCTGGTGCT GAGGCGCGAG
ATCGAGTCTA TGAAGGCGAG GCAGCCCCCC GGCCCCGGGG TTGGAGACAC GTATTCCATG
GTTTCCTACA GCGACACAGG CTCATCCACA GGCAGCCACG GCACCTCTAC AACCGTCAGC
TCGGCCAGGG AGCGGCTGCT GTGGCTTATA GACCTGATGG AGAATACATT AGACCTGGAA
GGAACCGGTG AGACCACCCA GGGCAGCACC AACGCTCTCC CGGATGTGTC TGTGGATGAT
GTCAAATCCC CCTCAGAAGA TCTGCCTGGT ATCAAGCCAC CTCCTCCCCC ACCACCCCTG
GCTCAAGGTC ATGACCGCTT GCTTGGCCAG CCACGGAAGC CAGGGAGGGA GGACCCCGCA
CCTCTGTCTT CTGCTGCCCA CTCAGGCATT GTCTTCTCAG CACCACGGAA CCGCAGCCCG
CCGCCAGGGA CTGCTCCCAC TCCGGGACCT TCCTCAGCAC AGGACTCTCC CTCCTCCCCC
ATTTATGCCT CCATCTCCCA TGCCAACCCC AGTTCCAGAA AGCCGCTGGA CACCCACCTG
GCCCTGGTTA ACCAGCACCC CATCGGCCCC TTCCCTCGAG TCCAGTCCCC ACCTCACCTG
AAGAGCCCTC CTGCAGAGAC CCCAGGAGCT GGGGCCTGCC TTCCACCACC ATCACCCTCT
GAACACCCTG ACGCCGTGGG TGCAAACCAG CACTTTGTTC TGGTGGAGGT GCACCGTCCG
GACAGTGAGC CTGATGTGAA TGAAGTGCGG GCTCTGCCCC AGACTCGCAC AGCCTCCACA
CTCTCTCAGC TCTCAGACAG TGGGCAGACC CTGAGCGAGG ACAGTGGCGT GGATGCCGGG
GAGACGGAGG CCAGCACCTC AGGCCGAGGC AGACAGACAG CATCCGCTAA GAACAAGAAT
GGCAAGGAGC AGCCCCGGAC GGAGAGGACC GCGGAGGGTG CCAACAAACC TCCCGGCCTG
CTGGAGCCAA CGTCCACCCT GGTCCGTGTG AGGAAAAGTG CAGCCACACT GGGCATCGCC
ATTGAGGGCG GTGCCAACAC ACGCCAGCCT CTGCCCAGGA TCGTCACAAT TCAGCGAGGA
GGTTCTGCCC ATAACTGTGG ACAGCTCAAG GTGGGCCACG TAATTCTGGA AGTGAATGGG
CAGACACTTC GGGGTAAGGA GCACAAGGAG GCCGCCCGAA TCATCGCTGA GGCCTTCAAG
ACCAAGGAGA GAGACTACAT CGACTTTCTG GTCACTGAGT TCAACGTGAT GCTCTAG

The stop codons will be deleted if pcDNA3.1-C-(k)DYK vector is selected.


CloneID OMu17862D
Sequence Information ORF Nucleotide Sequence (Length: 2736bp)
Protein sequence
SNP
Vector pcDNA3.1-C-(k)DYK or customized vector
Clone information Clone Map
Tag on pcDNA3.1-C-(k)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-FEB-2015
Organism Mus musculus (house mouse)
Product whirlin isoform 3
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK157955.1 and AY739116.1. On Feb 9, 2013 this sequence version replaced gi:57862815. Summary: This gene encodes a protein required for elongation and actin polymerization in the hair cell stereocilia. The encoded protein is localized to the cytoplasm and co-localizes with the growing end of actin filaments. Mutations in this gene have been linked to deafness. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2013]. Transcript Variant: This variant (3) uses an alternate in-frame splice site and lacks an in-frame exon in the coding region, compared to variant 2. The encoded isoform (3) is shorter than isoform 2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY739116.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
ATGAACGCAC AGCTGGACGG CCTGTCGGTG AGCTCGTCCT CCACCGGCTC GCTGGGCTCG 
GCGGCGGCGG CGGCGGGCGG CGGCGGGGGC GCGGGGTTGC GGCTGCTGTC TGCCAACGTG
CGCCAGCTGC ACCAAGCGCT CACGGCGCTG CTGAGCGAGC CCGAGCGGGA GCAGTTCACT
CACTGCCTCA ACGCGTACCA CGCGCGCCGC AACGTCTTCG ACCTGGTGCG CACCCTGCGC
GTCCTGCTGG ACAGCCCGGT CAAGCGGCGT CTGCTGCCCA TGCTGCGTCT GGTCATCCCG
CGCTCCGACC AGCTGCTCTT CGACCAGTAC ACGGCCGAGG GCCTCTACCT GCCAGCCACC
ACCCCCTACA GGCAGCCCGC CTGGGCCGCT CCCGACGGCG CGGGGCCCGG GGAGGTGCGA
CTCGTGAGCC TGCGGCGCGC CAAGGCCCAC GAGGGCTTGG GCTTCAGCAT CCGCGGGGGC
TCGGAACACG GCGTGGGCAT CTACGTGTCT CTAGTGGAGC CGGGCTCCCT GGCAGAGAAG
GAAGGGTTGC GGGTCGGGGA CCAGATTCTG CGCGTCAACG ATAAATCTCT AGCCCGGGTG
ACCCACGCGG AGGCTGTCAA GGCTCTCAAA GGCTCCAAGA AGCTGGTGCT GTCTGTATAC
TCAGCTGGGC GTATCCCAGG GGGCTATGTG ACCAACCACA TCTACACCTG GGTGGACCCA
CAGGGTCGAA GCACATCCCC TCCCTCCAGC CTGCCCCAGC CCCATGGCAG CACCCTGAGA
CAGCGTGAAG ATGACCGAAG GAGTACCCTC CACCTCCTGC AGAGTGGAGA TGAGAAAAAG
GTGAACCTGG TGTTGGGGGA CGGCCGGTCC TTGGGCCTCA CGATCCGAGG TGGAGCAGAG
TACGGCCTTG GCATTTACAT CACTGGTGTG GACCCAGGCT CTGAAGCAGA GAGCAGCGGC
CTCAAGGTTG GAGACCAGAT TCTGGAGGTG AATGGGCGGA GCTTTCTCAA CATCCTGCAT
GATGAGGCAG TGAAGCTGCT CAAGTCATCC CGGCACCTCA TCCTGACGGT GAAGGACGTC
GGAAGGCTGC CCCACGCACG TACCACCGTG GACCAGACCA AGTGGATCGC CAGTTCCCGG
ATCGGGGAAA GCGTCGCCAA CTCAGCAGGG TCTGGTCTCA GGTTTCCAGG GGACCACACA
GAAGAAGGGA CAAGCAAGCC AGGATTTTAC AAGGGCCCAG CCGGCTCCCA GGTGACCCTG
AGCAGCCTGG GGAATCAGAC TCGTGCACTG CTGGACGACC AAGCCAGGCA CCTGCTGACA
GAGCAGGAGC GCGCCACCAT GATGTACTAC CTGGCCCAGT ACCGTGGTGG CACCATCTCT
GTGGAGGCCA TGGTCATGGC ACTGTTTGAG TTGCTCAACA CACACGCCAA GTTCTCACTC
CTGTCTGAGG TGAGAAGCAT CATCTCACCC CAAGACCTGG ACCGCTTTGA CCACCTGGTG
CTGAGGCGCG AGATCGAGTC TATGAAGGCG AGGCAGCCCC CCGGCCCCGG GGTTGGAGAC
ACGTATTCCA TGGTTTCCTA CAGCGACACA GGCTCATCCA CAGGCAGCCA CGGCACCTCT
ACAACCGTCA GCTCGGCCAG GAATACATTA GACCTGGAAG GAACCGGTGA GACCACCCAG
GGCAGCACCA ACGCTCTCCC GGATGTGTCT GTGGATGATG TCAAATCCCC CTCAGAAGAT
CTGCCTGGTA TCAAGCCACC TCCTCCCCCA CCACCCCTGG CTCAAGGTCA TGACCGCTTG
CTTGGCCAGC CACGGAAGCC AGGGAGGGAG GACCCCGCAC CTCTGTCTTC TGCTGCCCAC
TCAGGCATTG TCTTCTCAGC ACCACGGAAC CGCAGCCCGC CGCCAGGGAC TGCTCCCACT
CCGGGACCTT CCTCAGCACA GGACTCTCCC TCCTCCCCCA TTTATGCCTC CATCTCCCAT
GCCAACCCCA GTTCCAGAAA GCCGCTGGAC ACCCACCTGG CCCTGGTTAA CCAGCACCCC
ATCGGCCCCT TCCCTCGAGT CCAGTCCCCA CCTCACCTGA AGAGCCCTCC TGCAGAGACC
CCAGGAGCTG GGGCCTGCCT TCCACCACCA TCACCCTCTG AACACCCTGA CGCCGTGGGT
GCAAACCAGC ACTTTGTTCT GGTGGAGGTG CACCGTCCGG ACAGTGAGCC TGATGTGAAT
GAAGTGCGGG CTCTGCCCCA GACTCGCACA GCCTCCACAC TCTCTCAGCT CTCAGACAGT
GGGCAGACCC TGAGCGAGGA CAGTGGCGTG GATGCCGGGG AGACGGAGGC CAGCACCTCA
GGCCGAGGCA GACAGACAGC ATCCGCTAAG AACAAGAATG GCAAGGAGCA GCCCCGGACG
GAGAGGACCG CGGAGGGTGC CAACAAACCT CCCGGCCTGC TGGAGCCAAC GTCCACCCTG
GTCCGTGTGA GGAAAAGTGC AGCCACACTG GGCATCGCCA TTGAGGGCGG TGCCAACACA
CGCCAGCCTC TGCCCAGGAT CGTCACAATT CAGCGAGGAG GTTCTGCCCA TAACTGTGGA
CAGCTCAAGG TGGGCCACGT AATTCTGGAA GTGAATGGGC AGACACTTCG GGGTAAGGAG
CACAAGGAGG CCGCCCGAAT CATCGCTGAG GCCTTCAAGA CCAAGGAGAG AGACTACATC
GACTTTCTGG TCACTGAGTT CAACGTGATG CTCTAG
The stop codons will be deleted if pcDNA3.1-C-(k)DYK vector is selected.
RefSeqNP_001008792.1
CDS759..3494
Misc Feature(1)606..608(+)
Misc Feature(2)870..1097(+)
Misc Feature(3)876..959(+)
Misc Feature(4)1173..1406(+)
Misc Feature(5)1212..1388(+)
Misc Feature(6)1590..1832(+)
Misc Feature(7)1626..1802(+)
Misc Feature(8)2028..2270(+)
Misc Feature(9)2031..2123(+)
Misc Feature(10)3216..3431(+)
Misc Feature(11)3246..3425(+)
Exon (1)1..1379
Gene:Whrn
Gene Synonym:
Exon (2)1380..1598
Gene:Whrn
Gene Synonym:
Exon (3)1599..1724
Gene:Whrn
Gene Synonym:
Exon (4)1725..1939
Gene:Whrn
Gene Synonym:
Exon (5)1940..1976
Gene:Whrn
Gene Synonym:
Exon (6)1977..2189
Gene:Whrn
Gene Synonym:
Exon (7)2190..2399
Gene:Whrn
Gene Synonym:
Exon (8)2400..2471
Gene:Whrn
Gene Synonym:
Exon (9)2472..3006
Gene:Whrn
Gene Synonym:
Exon (10)3007..3188
Gene:Whrn
Gene Synonym:
Exon (11)3189..3311
Gene:Whrn
Gene Synonym:
Exon (12)3312..4068
Gene:Whrn
Gene Synonym:
Translation
Position Chain Variation Link
413 413 -, cc dbSNP:235470811
893 893 a, g dbSNP:258826663
926 926 a, g dbSNP:221632230
993 993 c, t dbSNP:222841310
1061 1061 c, t dbSNP:253973828
1146 1146 a, g dbSNP:242225030
1162 1162 a, g dbSNP:258949563
1436 1436 a, t dbSNP:229464781
1448 1448 c, g dbSNP:248885091
1543 1543 a, g dbSNP:231349128
1655 1655 a, c dbSNP:237155388
1793 1793 a, g dbSNP:247019404
1946 1946 a, g dbSNP:265066394
2129 2129 c, t dbSNP:229444216
2130 2130 a, g dbSNP:257642857
2171 2171 a, g dbSNP:239773439
2210 2210 a, g dbSNP:27920291
2241 2241 c, t dbSNP:27920292
2267 2267 a, c dbSNP:232567681
2279 2279 c, t dbSNP:215654097
2289 2289 a, c dbSNP:263626317
2300 2300 c, g dbSNP:240313724
2342 2342 c, t dbSNP:212181156
2348 2348 a, g dbSNP:27920293
2423 2423 c, t dbSNP:27920358
2451 2451 a, g dbSNP:27920359
2459 2459 a, g dbSNP:213669003
2593 2593 a, c dbSNP:27920368
2594 2594 c, t dbSNP:224589614
2597 2597 a, t dbSNP:263759692
2681 2681 a, g dbSNP:240663587
2897 2897 c, t dbSNP:222457121
2910 2910 a, g dbSNP:247882268
2936 2936 c, t dbSNP:230379038
3039 3039 g, t dbSNP:264208410
3168 3168 c, g, t dbSNP:27920380
3197 3197 a, g dbSNP:256865838
3410 3410 c, t dbSNP:232997001
3415 3415 a, g dbSNP:27920395
3464 3464 c, t dbSNP:27920396
3508 3508 g, t dbSNP:235537939
3542 3542 c, t dbSNP:212416980
3567 3567 c, t dbSNP:254567383
3574 3574 a, g dbSNP:236434904
3580 3580 c, t dbSNP:215479081
3728 3728 a, g dbSNP:252080788
3770 3770 a, c dbSNP:227907253
3804 3804 a, g dbSNP:260402776
3861 3861 a, c dbSNP:248430395
3866 3866 c, t dbSNP:224190694
3909 3909 -, attt dbSNP:251337007
3931 3931 -, c dbSNP:386975477
3940 3940 -, cc dbSNP:233005657
3941 3941 -, ccc dbSNP:244841204
3942 3942 a, c dbSNP:47785708
3966 3966 c, t dbSNP:261916909

Target ORF information:

RefSeq Version NM_001008792
Organism Mus musculus (house mouse)
Definition Mus musculus whirlin (Whrn), transcript variant 3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1-C-(k)DYK
NM_001008792

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
ATGAACGCAC AGCTGGACGG CCTGTCGGTG AGCTCGTCCT CCACCGGCTC GCTGGGCTCG 
GCGGCGGCGG CGGCGGGCGG CGGCGGGGGC GCGGGGTTGC GGCTGCTGTC TGCCAACGTG
CGCCAGCTGC ACCAAGCGCT CACGGCGCTG CTGAGCGAGC CCGAGCGGGA GCAGTTCACT
CACTGCCTCA ACGCGTACCA CGCGCGCCGC AACGTCTTCG ACCTGGTGCG CACCCTGCGC
GTCCTGCTGG ACAGCCCGGT CAAGCGGCGT CTGCTGCCCA TGCTGCGTCT GGTCATCCCG
CGCTCCGACC AGCTGCTCTT CGACCAGTAC ACGGCCGAGG GCCTCTACCT GCCAGCCACC
ACCCCCTACA GGCAGCCCGC CTGGGCCGCT CCCGACGGCG CGGGGCCCGG GGAGGTGCGA
CTCGTGAGCC TGCGGCGCGC CAAGGCCCAC GAGGGCTTGG GCTTCAGCAT CCGCGGGGGC
TCGGAACACG GCGTGGGCAT CTACGTGTCT CTAGTGGAGC CGGGCTCCCT GGCAGAGAAG
GAAGGGTTGC GGGTCGGGGA CCAGATTCTG CGCGTCAACG ATAAATCTCT AGCCCGGGTG
ACCCACGCGG AGGCTGTCAA GGCTCTCAAA GGCTCCAAGA AGCTGGTGCT GTCTGTATAC
TCAGCTGGGC GTATCCCAGG GGGCTATGTG ACCAACCACA TCTACACCTG GGTGGACCCA
CAGGGTCGAA GCACATCCCC TCCCTCCAGC CTGCCCCAGC CCCATGGCAG CACCCTGAGA
CAGCGTGAAG ATGACCGAAG GAGTACCCTC CACCTCCTGC AGAGTGGAGA TGAGAAAAAG
GTGAACCTGG TGTTGGGGGA CGGCCGGTCC TTGGGCCTCA CGATCCGAGG TGGAGCAGAG
TACGGCCTTG GCATTTACAT CACTGGTGTG GACCCAGGCT CTGAAGCAGA GAGCAGCGGC
CTCAAGGTTG GAGACCAGAT TCTGGAGGTG AATGGGCGGA GCTTTCTCAA CATCCTGCAT
GATGAGGCAG TGAAGCTGCT CAAGTCATCC CGGCACCTCA TCCTGACGGT GAAGGACGTC
GGAAGGCTGC CCCACGCACG TACCACCGTG GACCAGACCA AGTGGATCGC CAGTTCCCGG
ATCGGGGAAA GCGTCGCCAA CTCAGCAGGG TCTGGTCTCA GGTTTCCAGG GGACCACACA
GAAGAAGGGA CAAGCAAGCC AGGATTTTAC AAGGGCCCAG CCGGCTCCCA GGTGACCCTG
AGCAGCCTGG GGAATCAGAC TCGTGCACTG CTGGACGACC AAGCCAGGCA CCTGCTGACA
GAGCAGGAGC GCGCCACCAT GATGTACTAC CTGGCCCAGT ACCGTGGTGG CACCATCTCT
GTGGAGGCCA TGGTCATGGC ACTGTTTGAG TTGCTCAACA CACACGCCAA GTTCTCACTC
CTGTCTGAGG TGAGAAGCAT CATCTCACCC CAAGACCTGG ACCGCTTTGA CCACCTGGTG
CTGAGGCGCG AGATCGAGTC TATGAAGGCG AGGCAGCCCC CCGGCCCCGG GGTTGGAGAC
ACGTATTCCA TGGTTTCCTA CAGCGACACA GGCTCATCCA CAGGCAGCCA CGGCACCTCT
ACAACCGTCA GCTCGGCCAG GAATACATTA GACCTGGAAG GAACCGGTGA GACCACCCAG
GGCAGCACCA ACGCTCTCCC GGATGTGTCT GTGGATGATG TCAAATCCCC CTCAGAAGAT
CTGCCTGGTA TCAAGCCACC TCCTCCCCCA CCACCCCTGG CTCAAGGTCA TGACCGCTTG
CTTGGCCAGC CACGGAAGCC AGGGAGGGAG GACCCCGCAC CTCTGTCTTC TGCTGCCCAC
TCAGGCATTG TCTTCTCAGC ACCACGGAAC CGCAGCCCGC CGCCAGGGAC TGCTCCCACT
CCGGGACCTT CCTCAGCACA GGACTCTCCC TCCTCCCCCA TTTATGCCTC CATCTCCCAT
GCCAACCCCA GTTCCAGAAA GCCGCTGGAC ACCCACCTGG CCCTGGTTAA CCAGCACCCC
ATCGGCCCCT TCCCTCGAGT CCAGTCCCCA CCTCACCTGA AGAGCCCTCC TGCAGAGACC
CCAGGAGCTG GGGCCTGCCT TCCACCACCA TCACCCTCTG AACACCCTGA CGCCGTGGGT
GCAAACCAGC ACTTTGTTCT GGTGGAGGTG CACCGTCCGG ACAGTGAGCC TGATGTGAAT
GAAGTGCGGG CTCTGCCCCA GACTCGCACA GCCTCCACAC TCTCTCAGCT CTCAGACAGT
GGGCAGACCC TGAGCGAGGA CAGTGGCGTG GATGCCGGGG AGACGGAGGC CAGCACCTCA
GGCCGAGGCA GACAGACAGC ATCCGCTAAG AACAAGAATG GCAAGGAGCA GCCCCGGACG
GAGAGGACCG CGGAGGGTGC CAACAAACCT CCCGGCCTGC TGGAGCCAAC GTCCACCCTG
GTCCGTGTGA GGAAAAGTGC AGCCACACTG GGCATCGCCA TTGAGGGCGG TGCCAACACA
CGCCAGCCTC TGCCCAGGAT CGTCACAATT CAGCGAGGAG GTTCTGCCCA TAACTGTGGA
CAGCTCAAGG TGGGCCACGT AATTCTGGAA GTGAATGGGC AGACACTTCG GGGTAAGGAG
CACAAGGAGG CCGCCCGAAT CATCGCTGAG GCCTTCAAGA CCAAGGAGAG AGACTACATC
GACTTTCTGG TCACTGAGTT CAACGTGATG CTCTAG

The stop codons will be deleted if pcDNA3.1-C-(k)DYK vector is selected.


CloneID OMu17807D
Sequence Information ORF Nucleotide Sequence (Length: 2721bp)
Protein sequence
SNP
Vector pcDNA3.1-C-(k)DYK or customized vector
Clone information Clone Map
Tag on pcDNA3.1-C-(k)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-FEB-2015
Organism Mus musculus (house mouse)
Product whirlin isoform 4
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK157955.1 and AY739117.1. On Feb 9, 2013 this sequence version replaced gi:57526157. Summary: This gene encodes a protein required for elongation and actin polymerization in the hair cell stereocilia. The encoded protein is localized to the cytoplasm and co-localizes with the growing end of actin filaments. Mutations in this gene have been linked to deafness. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2013]. Transcript Variant: This variant (4) lacks an in-frame exon and uses an alternate in-frame splice site in the coding region, compared to variant 2. The encoded isoform (4) is shorter than isoform 2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY739117.1, AK122523.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
ATGAACGCAC AGCTGGACGG CCTGTCGGTG AGCTCGTCCT CCACCGGCTC GCTGGGCTCG 
GCGGCGGCGG CGGCGGGCGG CGGCGGGGGC GCGGGGTTGC GGCTGCTGTC TGCCAACGTG
CGCCAGCTGC ACCAAGCGCT CACGGCGCTG CTGAGCGAGC CCGAGCGGGA GCAGTTCACT
CACTGCCTCA ACGCGTACCA CGCGCGCCGC AACGTCTTCG ACCTGGTGCG CACCCTGCGC
GTCCTGCTGG ACAGCCCGGT CAAGCGGCGT CTGCTGCCCA TGCTGCGTCT GGTCATCCCG
CGCTCCGACC AGCTGCTCTT CGACCAGTAC ACGGCCGAGG GCCTCTACCT GCCAGCCACC
ACCCCCTACA GGCAGCCCGC CTGGGCCGCT CCCGACGGCG CGGGGCCCGG GGAGGTGCGA
CTCGTGAGCC TGCGGCGCGC CAAGGCCCAC GAGGGCTTGG GCTTCAGCAT CCGCGGGGGC
TCGGAACACG GCGTGGGCAT CTACGTGTCT CTAGTGGAGC CGGGCTCCCT GGCAGAGAAG
GAAGGGTTGC GGGTCGGGGA CCAGATTCTG CGCGTCAACG ATAAATCTCT AGCCCGGGTG
ACCCACGCGG AGGCTGTCAA GGCTCTCAAA GGCTCCAAGA AGCTGGTGCT GTCTGTATAC
TCAGCTGGGC GTATCCCAGG GGGCTATGTG ACCAACCACA TCTACACCTG GGTGGACCCA
CAGGGTCGAA GCACATCCCC TCCCTCCAGC CTGCCCCAGC CCCATGGCAG CACCCTGAGA
CAGCGTGAAG ATGACCGAAG GAGTACCCTC CACCTCCTGC AGAGTGGAGA TGAGAAAAAG
GTGAACCTGG TGTTGGGGGA CGGCCGGTCC TTGGGCCTCA CGATCCGAGG TGGAGCAGAG
TACGGCCTTG GCATTTACAT CACTGGTGTG GACCCAGGCT CTGAAGCAGA GAGCAGCGGC
CTCAAGGTTG GAGACCAGAT TCTGGAGGTG AATGGGCGGA GCTTTCTCAA CATCCTGCAT
GATGAGGCAG TGAAGCTGCT CAAGTCATCC CGGCACCTCA TCCTGACGGT GAAGGACGTC
GGAAGGCTGC CCCACGCACG TACCACCGTG GACCAGACCA AGTGGATCGC CAGTTCCCGG
ATCGGGGAAA GCGTCGCCAA CTCAGCAGGG TTTCCAGGGG ACCACACAGA AGAAGGGACA
AGCAAGCCAG GATTTTACAA GGGCCCAGCC GGCTCCCAGG TGACCCTGAG CAGCCTGGGG
AATCAGACTC GTGCACTGCT GGACGACCAA GCCAGGCACC TGCTGACAGA GCAGGAGCGC
GCCACCATGA TGTACTACCT GGCCCAGTAC CGTGGTGGCA CCATCTCTGT GGAGGCCATG
GTCATGGCAC TGTTTGAGTT GCTCAACACA CACGCCAAGT TCTCACTCCT GTCTGAGGTG
AGAAGCATCA TCTCACCCCA AGACCTGGAC CGCTTTGACC ACCTGGTGCT GAGGCGCGAG
ATCGAGTCTA TGAAGGCGAG GCAGCCCCCC GGCCCCGGGG TTGGAGACAC GTATTCCATG
GTTTCCTACA GCGACACAGG CTCATCCACA GGCAGCCACG GCACCTCTAC AACCGTCAGC
TCGGCCAGGA ATACATTAGA CCTGGAAGGA ACCGGTGAGA CCACCCAGGG CAGCACCAAC
GCTCTCCCGG ATGTGTCTGT GGATGATGTC AAATCCCCCT CAGAAGATCT GCCTGGTATC
AAGCCACCTC CTCCCCCACC ACCCCTGGCT CAAGGTCATG ACCGCTTGCT TGGCCAGCCA
CGGAAGCCAG GGAGGGAGGA CCCCGCACCT CTGTCTTCTG CTGCCCACTC AGGCATTGTC
TTCTCAGCAC CACGGAACCG CAGCCCGCCG CCAGGGACTG CTCCCACTCC GGGACCTTCC
TCAGCACAGG ACTCTCCCTC CTCCCCCATT TATGCCTCCA TCTCCCATGC CAACCCCAGT
TCCAGAAAGC CGCTGGACAC CCACCTGGCC CTGGTTAACC AGCACCCCAT CGGCCCCTTC
CCTCGAGTCC AGTCCCCACC TCACCTGAAG AGCCCTCCTG CAGAGACCCC AGGAGCTGGG
GCCTGCCTTC CACCACCATC ACCCTCTGAA CACCCTGACG CCGTGGGTGC AAACCAGCAC
TTTGTTCTGG TGGAGGTGCA CCGTCCGGAC AGTGAGCCTG ATGTGAATGA AGTGCGGGCT
CTGCCCCAGA CTCGCACCTC CACACTCTCT CAGCTCTCAG ACAGTGGGCA GACCCTGAGC
GAGGACAGTG GCGTGGATGC CGGGGAGACG GAGGCCAGCA CCTCAGGCCG AGGCAGACAG
ACAGCATCCG CTAAGAACAA GAATGGCAAG GAGCAGCCCC GGACGGAGAG GACCGCGGAG
GGTGCCAACA AACCTCCCGG CCTGCTGGAG CCAACGTCCA CCCTGGTCCG TGTGAGGAAA
AGTGCAGCCA CACTGGGCAT CGCCATTGAG GGCGGTGCCA ACACACGCCA GCCTCTGCCC
AGGATCGTCA CAATTCAGCG AGGAGGTTCT GCCCATAACT GTGGACAGCT CAAGGTGGGC
CACGTAATTC TGGAAGTGAA TGGGCAGACA CTTCGGGGTA AGGAGCACAA GGAGGCCGCC
CGAATCATCG CTGAGGCCTT CAAGACCAAG GAGAGAGACT ACATCGACTT TCTGGTCACT
GAGTTCAACG TGATGCTCTTA G
The stop codons will be deleted if pcDNA3.1-C-(k)DYK vector is selected.
RefSeqNP_001008793.1
CDS759..3479
Misc Feature(1)606..608(+)
Misc Feature(2)870..1097(+)
Misc Feature(3)876..959(+)
Misc Feature(4)1173..1406(+)
Misc Feature(5)1212..1388(+)
Misc Feature(6)1590..1832(+)
Misc Feature(7)1626..1802(+)
Misc Feature(8)2016..2258(+)
Misc Feature(9)2019..2111(+)
Misc Feature(10)3201..3416(+)
Misc Feature(11)3231..3410(+)
Exon (1)1..1379
Gene:Whrn
Gene Synonym:
Exon (2)1380..1598
Gene:Whrn
Gene Synonym:
Exon (3)1599..1724
Gene:Whrn
Gene Synonym:
Exon (4)1725..1927
Gene:Whrn
Gene Synonym:
Exon (5)1928..1964
Gene:Whrn
Gene Synonym:
Exon (6)1965..2177
Gene:Whrn
Gene Synonym:
Exon (7)2178..2387
Gene:Whrn
Gene Synonym:
Exon (8)2388..2459
Gene:Whrn
Gene Synonym:
Exon (9)2460..2994
Gene:Whrn
Gene Synonym:
Exon (10)2995..3173
Gene:Whrn
Gene Synonym:
Exon (11)3174..3296
Gene:Whrn
Gene Synonym:
Exon (12)3297..4053
Gene:Whrn
Gene Synonym:
Translation
Position Chain Variation Link
413 413 -, cc dbSNP:235470811
893 893 a, g dbSNP:258826663
926 926 a, g dbSNP:221632230
993 993 c, t dbSNP:222841310
1061 1061 c, t dbSNP:253973828
1146 1146 a, g dbSNP:242225030
1162 1162 a, g dbSNP:258949563
1436 1436 a, t dbSNP:229464781
1448 1448 c, g dbSNP:248885091
1543 1543 a, g dbSNP:231349128
1655 1655 a, c dbSNP:237155388
1793 1793 a, g dbSNP:247019404
1934 1934 a, g dbSNP:265066394
2117 2117 c, t dbSNP:229444216
2118 2118 a, g dbSNP:257642857
2159 2159 a, g dbSNP:239773439
2198 2198 a, g dbSNP:27920291
2229 2229 c, t dbSNP:27920292
2255 2255 a, c dbSNP:232567681
2267 2267 c, t dbSNP:215654097
2277 2277 a, c dbSNP:263626317
2288 2288 c, g dbSNP:240313724
2330 2330 c, t dbSNP:212181156
2336 2336 a, g dbSNP:27920293
2411 2411 c, t dbSNP:27920358
2439 2439 a, g dbSNP:27920359
2447 2447 a, g dbSNP:213669003
2581 2581 a, c dbSNP:27920368
2582 2582 c, t dbSNP:224589614
2585 2585 a, t dbSNP:263759692
2669 2669 a, g dbSNP:240663587
2885 2885 c, t dbSNP:222457121
2898 2898 a, g dbSNP:247882268
2924 2924 c, t dbSNP:230379038
3024 3024 g, t dbSNP:264208410
3153 3153 c, g, t dbSNP:27920380
3182 3182 a, g dbSNP:256865838
3395 3395 c, t dbSNP:232997001
3400 3400 a, g dbSNP:27920395
3449 3449 c, t dbSNP:27920396
3493 3493 g, t dbSNP:235537939
3527 3527 c, t dbSNP:212416980
3552 3552 c, t dbSNP:254567383
3559 3559 a, g dbSNP:236434904
3565 3565 c, t dbSNP:215479081
3713 3713 a, g dbSNP:252080788
3755 3755 a, c dbSNP:227907253
3789 3789 a, g dbSNP:260402776
3846 3846 a, c dbSNP:248430395
3851 3851 c, t dbSNP:224190694
3894 3894 -, attt dbSNP:251337007
3916 3916 -, c dbSNP:386975477
3925 3925 -, cc dbSNP:233005657
3926 3926 -, ccc dbSNP:244841204
3927 3927 a, c dbSNP:47785708
3951 3951 c, t dbSNP:261916909

Target ORF information:

RefSeq Version NM_001008793
Organism Mus musculus (house mouse)
Definition Mus musculus whirlin (Whrn), transcript variant 4, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1-C-(k)DYK
NM_001008793

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
ATGAACGCAC AGCTGGACGG CCTGTCGGTG AGCTCGTCCT CCACCGGCTC GCTGGGCTCG 
GCGGCGGCGG CGGCGGGCGG CGGCGGGGGC GCGGGGTTGC GGCTGCTGTC TGCCAACGTG
CGCCAGCTGC ACCAAGCGCT CACGGCGCTG CTGAGCGAGC CCGAGCGGGA GCAGTTCACT
CACTGCCTCA ACGCGTACCA CGCGCGCCGC AACGTCTTCG ACCTGGTGCG CACCCTGCGC
GTCCTGCTGG ACAGCCCGGT CAAGCGGCGT CTGCTGCCCA TGCTGCGTCT GGTCATCCCG
CGCTCCGACC AGCTGCTCTT CGACCAGTAC ACGGCCGAGG GCCTCTACCT GCCAGCCACC
ACCCCCTACA GGCAGCCCGC CTGGGCCGCT CCCGACGGCG CGGGGCCCGG GGAGGTGCGA
CTCGTGAGCC TGCGGCGCGC CAAGGCCCAC GAGGGCTTGG GCTTCAGCAT CCGCGGGGGC
TCGGAACACG GCGTGGGCAT CTACGTGTCT CTAGTGGAGC CGGGCTCCCT GGCAGAGAAG
GAAGGGTTGC GGGTCGGGGA CCAGATTCTG CGCGTCAACG ATAAATCTCT AGCCCGGGTG
ACCCACGCGG AGGCTGTCAA GGCTCTCAAA GGCTCCAAGA AGCTGGTGCT GTCTGTATAC
TCAGCTGGGC GTATCCCAGG GGGCTATGTG ACCAACCACA TCTACACCTG GGTGGACCCA
CAGGGTCGAA GCACATCCCC TCCCTCCAGC CTGCCCCAGC CCCATGGCAG CACCCTGAGA
CAGCGTGAAG ATGACCGAAG GAGTACCCTC CACCTCCTGC AGAGTGGAGA TGAGAAAAAG
GTGAACCTGG TGTTGGGGGA CGGCCGGTCC TTGGGCCTCA CGATCCGAGG TGGAGCAGAG
TACGGCCTTG GCATTTACAT CACTGGTGTG GACCCAGGCT CTGAAGCAGA GAGCAGCGGC
CTCAAGGTTG GAGACCAGAT TCTGGAGGTG AATGGGCGGA GCTTTCTCAA CATCCTGCAT
GATGAGGCAG TGAAGCTGCT CAAGTCATCC CGGCACCTCA TCCTGACGGT GAAGGACGTC
GGAAGGCTGC CCCACGCACG TACCACCGTG GACCAGACCA AGTGGATCGC CAGTTCCCGG
ATCGGGGAAA GCGTCGCCAA CTCAGCAGGG TTTCCAGGGG ACCACACAGA AGAAGGGACA
AGCAAGCCAG GATTTTACAA GGGCCCAGCC GGCTCCCAGG TGACCCTGAG CAGCCTGGGG
AATCAGACTC GTGCACTGCT GGACGACCAA GCCAGGCACC TGCTGACAGA GCAGGAGCGC
GCCACCATGA TGTACTACCT GGCCCAGTAC CGTGGTGGCA CCATCTCTGT GGAGGCCATG
GTCATGGCAC TGTTTGAGTT GCTCAACACA CACGCCAAGT TCTCACTCCT GTCTGAGGTG
AGAAGCATCA TCTCACCCCA AGACCTGGAC CGCTTTGACC ACCTGGTGCT GAGGCGCGAG
ATCGAGTCTA TGAAGGCGAG GCAGCCCCCC GGCCCCGGGG TTGGAGACAC GTATTCCATG
GTTTCCTACA GCGACACAGG CTCATCCACA GGCAGCCACG GCACCTCTAC AACCGTCAGC
TCGGCCAGGA ATACATTAGA CCTGGAAGGA ACCGGTGAGA CCACCCAGGG CAGCACCAAC
GCTCTCCCGG ATGTGTCTGT GGATGATGTC AAATCCCCCT CAGAAGATCT GCCTGGTATC
AAGCCACCTC CTCCCCCACC ACCCCTGGCT CAAGGTCATG ACCGCTTGCT TGGCCAGCCA
CGGAAGCCAG GGAGGGAGGA CCCCGCACCT CTGTCTTCTG CTGCCCACTC AGGCATTGTC
TTCTCAGCAC CACGGAACCG CAGCCCGCCG CCAGGGACTG CTCCCACTCC GGGACCTTCC
TCAGCACAGG ACTCTCCCTC CTCCCCCATT TATGCCTCCA TCTCCCATGC CAACCCCAGT
TCCAGAAAGC CGCTGGACAC CCACCTGGCC CTGGTTAACC AGCACCCCAT CGGCCCCTTC
CCTCGAGTCC AGTCCCCACC TCACCTGAAG AGCCCTCCTG CAGAGACCCC AGGAGCTGGG
GCCTGCCTTC CACCACCATC ACCCTCTGAA CACCCTGACG CCGTGGGTGC AAACCAGCAC
TTTGTTCTGG TGGAGGTGCA CCGTCCGGAC AGTGAGCCTG ATGTGAATGA AGTGCGGGCT
CTGCCCCAGA CTCGCACCTC CACACTCTCT CAGCTCTCAG ACAGTGGGCA GACCCTGAGC
GAGGACAGTG GCGTGGATGC CGGGGAGACG GAGGCCAGCA CCTCAGGCCG AGGCAGACAG
ACAGCATCCG CTAAGAACAA GAATGGCAAG GAGCAGCCCC GGACGGAGAG GACCGCGGAG
GGTGCCAACA AACCTCCCGG CCTGCTGGAG CCAACGTCCA CCCTGGTCCG TGTGAGGAAA
AGTGCAGCCA CACTGGGCAT CGCCATTGAG GGCGGTGCCA ACACACGCCA GCCTCTGCCC
AGGATCGTCA CAATTCAGCG AGGAGGTTCT GCCCATAACT GTGGACAGCT CAAGGTGGGC
CACGTAATTC TGGAAGTGAA TGGGCAGACA CTTCGGGGTA AGGAGCACAA GGAGGCCGCC
CGAATCATCG CTGAGGCCTT CAAGACCAAG GAGAGAGACT ACATCGACTT TCTGGTCACT
GAGTTCAACG TGATGCTCTTA G

The stop codons will be deleted if pcDNA3.1-C-(k)DYK vector is selected.


CloneID OMu17779D
Sequence Information ORF Nucleotide Sequence (Length: 969bp)
Protein sequence
SNP
Vector pcDNA3.1-C-(k)DYK or customized vector
Clone information Clone Map
Tag on pcDNA3.1-C-(k)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-FEB-2015
Organism Mus musculus (house mouse)
Product whirlin isoform 10
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK157955.1 and HQ148553.1. Summary: This gene encodes a protein required for elongation and actin polymerization in the hair cell stereocilia. The encoded protein is localized to the cytoplasm and co-localizes with the growing end of actin filaments. Mutations in this gene have been linked to deafness. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2013]. Transcript Variant: This variant (10) uses an alternate 3' terminal exon, compared to variant 2. It encodes isoform 10 which is shorter and has a distinct C-terminus, compared to isoform 2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: HQ148553.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849377, SAMN00849379 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
ATGAACGCAC AGCTGGACGG CCTGTCGGTG AGCTCGTCCT CCACCGGCTC GCTGGGCTCG 
GCGGCGGCGG CGGCGGGCGG CGGCGGGGGC GCGGGGTTGC GGCTGCTGTC TGCCAACGTG
CGCCAGCTGC ACCAAGCGCT CACGGCGCTG CTGAGCGAGC CCGAGCGGGA GCAGTTCACT
CACTGCCTCA ACGCGTACCA CGCGCGCCGC AACGTCTTCG ACCTGGTGCG CACCCTGCGC
GTCCTGCTGG ACAGCCCGGT CAAGCGGCGT CTGCTGCCCA TGCTGCGTCT GGTCATCCCG
CGCTCCGACC AGCTGCTCTT CGACCAGTAC ACGGCCGAGG GCCTCTACCT GCCAGCCACC
ACCCCCTACA GGCAGCCCGC CTGGGCCGCT CCCGACGGCG CGGGGCCCGG GGAGGTGCGA
CTCGTGAGCC TGCGGCGCGC CAAGGCCCAC GAGGGCTTGG GCTTCAGCAT CCGCGGGGGC
TCGGAACACG GCGTGGGCAT CTACGTGTCT CTAGTGGAGC CGGGCTCCCT GGCAGAGAAG
GAAGGGTTGC GGGTCGGGGA CCAGATTCTG CGCGTCAACG ATAAATCTCT AGCCCGGGTG
ACCCACGCGG AGGCTGTCAA GGCTCTCAAA GGCTCCAAGA AGCTGGTGCT GTCTGTATAC
TCAGCTGGGC GTATCCCAGG GGGCTATGTG ACCAACCACA TCTACACCTG GGTGGACCCA
CAGGGTCGAA GCACATCCCC TCCCTCCAGC CTGCCCCAGC CCCATGGCAG CACCCTGAGA
CAGCGTGAAG ATGACCGAAG GAGTACCCTC CACCTCCTGC AGAGTGGAGA TGAGAAAAAG
GTGAACCTGG TGTTGGGGGA CGGCCGGTCC TTGGGCCTCA CGATCCGAGG TGGAGCAGAG
TACGGCCTTG GCATTTACAT CACTGGTGTG GACCCAGGCT CTGAAGCAGA GAGCAGCGGC
CTCAAGTGA
The stop codons will be deleted if pcDNA3.1-C-(k)DYK vector is selected.
RefSeqNP_001263300.1
CDS759..1727
Misc Feature(1)606..608(+)
Misc Feature(2)870..1097(+)
Misc Feature(3)876..959(+)
Misc Feature(4)1173..1406(+)
Misc Feature(5)1212..1388(+)
Misc Feature(6)1590..>1724(+)
Misc Feature(7)1626..1643(+)
Exon (1)1..1379
Gene:Whrn
Gene Synonym:
Exon (2)1380..1598
Gene:Whrn
Gene Synonym:
Exon (3)1599..1724
Gene:Whrn
Gene Synonym:
Exon (4)1725..2029
Gene:Whrn
Gene Synonym:
Translation
Position Chain Variation Link
413 413 -, cc dbSNP:235470811
893 893 a, g dbSNP:258826663
926 926 a, g dbSNP:221632230
993 993 c, t dbSNP:222841310
1061 1061 c, t dbSNP:253973828
1146 1146 a, g dbSNP:242225030
1162 1162 a, g dbSNP:258949563
1436 1436 a, t dbSNP:229464781
1448 1448 c, g dbSNP:248885091
1543 1543 a, g dbSNP:231349128
1655 1655 a, c dbSNP:237155388
1733 1733 c, t dbSNP:232744290
1766 1766 -, cacaac dbSNP:256009310
1800 1800 c, g dbSNP:215386701
1838 1838 a, g dbSNP:246129858
1891 1891 a, g dbSNP:242051034
2007 2007 a, g dbSNP:228927875

Target ORF information:

RefSeq Version NM_001276371
Organism Mus musculus (house mouse)
Definition Mus musculus whirlin (Whrn), transcript variant 10, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1-C-(k)DYK
NM_001276371

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
ATGAACGCAC AGCTGGACGG CCTGTCGGTG AGCTCGTCCT CCACCGGCTC GCTGGGCTCG 
GCGGCGGCGG CGGCGGGCGG CGGCGGGGGC GCGGGGTTGC GGCTGCTGTC TGCCAACGTG
CGCCAGCTGC ACCAAGCGCT CACGGCGCTG CTGAGCGAGC CCGAGCGGGA GCAGTTCACT
CACTGCCTCA ACGCGTACCA CGCGCGCCGC AACGTCTTCG ACCTGGTGCG CACCCTGCGC
GTCCTGCTGG ACAGCCCGGT CAAGCGGCGT CTGCTGCCCA TGCTGCGTCT GGTCATCCCG
CGCTCCGACC AGCTGCTCTT CGACCAGTAC ACGGCCGAGG GCCTCTACCT GCCAGCCACC
ACCCCCTACA GGCAGCCCGC CTGGGCCGCT CCCGACGGCG CGGGGCCCGG GGAGGTGCGA
CTCGTGAGCC TGCGGCGCGC CAAGGCCCAC GAGGGCTTGG GCTTCAGCAT CCGCGGGGGC
TCGGAACACG GCGTGGGCAT CTACGTGTCT CTAGTGGAGC CGGGCTCCCT GGCAGAGAAG
GAAGGGTTGC GGGTCGGGGA CCAGATTCTG CGCGTCAACG ATAAATCTCT AGCCCGGGTG
ACCCACGCGG AGGCTGTCAA GGCTCTCAAA GGCTCCAAGA AGCTGGTGCT GTCTGTATAC
TCAGCTGGGC GTATCCCAGG GGGCTATGTG ACCAACCACA TCTACACCTG GGTGGACCCA
CAGGGTCGAA GCACATCCCC TCCCTCCAGC CTGCCCCAGC CCCATGGCAG CACCCTGAGA
CAGCGTGAAG ATGACCGAAG GAGTACCCTC CACCTCCTGC AGAGTGGAGA TGAGAAAAAG
GTGAACCTGG TGTTGGGGGA CGGCCGGTCC TTGGGCCTCA CGATCCGAGG TGGAGCAGAG
TACGGCCTTG GCATTTACAT CACTGGTGTG GACCCAGGCT CTGAAGCAGA GAGCAGCGGC
CTCAAGTGA

The stop codons will be deleted if pcDNA3.1-C-(k)DYK vector is selected.