Recombinant stable cell lines are one of the widely used tools in drug discovery, toxicity testing, and basic research. Long-term stable expression of a gene of interest (GOI) is usually achieved by transfection or viral transduction of a vector containing the expression cassette of the GOI together with a selection marker (antibiotics or fluorescent proteins). In contrast to transient expression, stable cell line offers reproducible results for assay studies. Read More »
Stable Cell Line Services: Advantages working with GenScript CellPower™
Stable Cell Line Development services by CellPower™
Over-expression of GOI
Figure 1. PD1 expression by FACS analysis (left) and binding assay (right) in CHO-K1/PD1 cells.
Knock-down Expression of GOI
Figure 2. Validation of knockdown efficiency via western blotting (left) and functional assay (right).
Inducible expression of GOI
Figure 3. Q‐PCR (left) and western blotting (right) validation of Target A expression in HepG2 cells.
Figure 4. Knockout of Target B in HepG2 cells validated by sequencing (above) and western blotting analysis (below).
Workflow of Our CellPower™ Stable Cell Line Development Process
Engineered Stable Cell Line Products
GenScript offers a wide selection of Immune Checkpoint Stable Cell Lines and GPCR Stable Cell Lines to accelerate your drug discovery. See more product introduction.
Also available are stable cell lines for protein production. See our Production Grade Stable Cell Line webpage for more details.