| Full Name |
Neuroserpin Antibody, pAb, Rabbit
|
Abbreviated name-1 |
Serpin I1 antibody |
|
Description |
Neuroserpin is a member of the serpin superfamily. It is secreted from axonal growth cones of the CNS and PNS where it inhibits the enzyme tissue plasminogen activator. Neuroserpin participates in regulating axonal growth, reducing seizure activity, controlling damage in cerebral infarction, and regulating emotional behavior and memory. This protein is expressed in brain.
GenScript Rabbit Anti-Neuroserpin Polyclonal Antibody is developed in rabbit using a KLH-coupled synthetic peptide from C-terminal of human Neuroserpin (Swiss Prot: Q99574). |
Ig Subclass |
Rabbit IgG |
Storage |
GenScript Rabbit Anti-Neuroserpin Polyclonal Antibody should be stored lyophilized until use. It remains stable in lyophilized form for at least two years if stored at -20°C or below. The reconstituted antibody can be stored for two to three weeks at 2-8°C or for up to 12 months at -20°C or below. Avoid repeated freeze and thaw cycles. |
Specificity |
GenScript Rabbit Anti-Neuroserpin Polyclonal Antibody detects endogenous levels of mouse and rat Neuroserpin. It is predicted to react with human Neuroserpin according to sequence homology.
Positive control:mouse brain and rat brain. |
Concentration |
0.5 mg/ml, lyophilized with PBS, pH 7.4, containing 0.02% sodium azide |
Immunogen |
KLH-coupled synthetic peptide from C-terminal of human Neuroserpin (Swiss Prot: Q99574). |
Purification Method |
Immunoaffinity chromatography |
Reconstitution |
Reconstitute the lyophilized powder with 80 µl of deionized water (or equivalent) to an antibody concentration of 0.5 mg/ml. |
Applications |
Working concentrations for specific applications should be determined by the investigator. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.
Western blot: 1-2 µg/ml
Other Applications: user -optimized |
Conjugation |
Unconjugated |
Species Reactivity |
Mouse and rat. This product has not been tested with other species yet. |
Host Species |
Rabbit |
Note |
Small volumes of antibody will occasionally become entrapped in the seal of the product vial during shipment and storage. Before use, briefly centrifuge the vial to dislodge any liquid in the container's cap. |
MSDS: 20090827084838 (PDF)
