| Full Name |
β-Amyloid (1-28) |
| Alias |
Abeta 1-28 |
|
Sequence (one-letter code) |
DAEFRHDSGYEVHHQKLVFFAEDVGSNK |
Sequence (three-letter code) |
{ASP}{ALA}{GLU}{PHE}{ARG}{HIS}{ASP}{SER}{GLY}{TYR}{GLU}{VAL}{HIS}{HIS}{GLN}{LYS}{LEU}{VAL}{PHE}{PHE}{ALA}{GLU}{ASP}{VAL}{GLY}{SER}{ASN}{LYS} |
| Description |
Beta amyloid is an extracellular filamentous protein deposit found in the brain. It is the major protein component of amyloid cores and neuritic plaques and is also found as a deposit in neurofibrillary tangles. Beta-amyloid peptide (Abeta), the major constituent of amyloid plaques in the brains of Alzheimerâs patients, is thought to be the cause of Alzheimerâs Disease (AD). Beta-amyloid peptide is generated from the beta-amyloid precursor protein (beta APP) in a two-step process. |
| Solubility |
Soluble in water. The contents of this vial have been accurately determined. Both the stopper and the vial have been siliconized. Do not attempt to weight out a smaller portion of the contents. |
| Purity |
> 95% |
| Storage |
Store at -20°C. |
| Notes |
Forms fibrils that have the same antigenic and structural features as the native Alzheimer Disease Amyloid filaments. |